drTarget proposed protein targets for CoViD participating in pathways involved in SARS coronavirus disease by Reactome

All the interactions of these  proteins linked to SARS pathways annotated in Reactome DB with actual or predicted SARS active compounds. 

All proteins linked to SARS pathways annotated in Reactome DB interaction map. Protein colors by organism.

Note how SARS pathways from reactome contain proteins identified by drTarget algorithms as relevant for coronavirus infections.
geneName protName avgSARSScore kindOfValue organismType Degree protein_class_name
rep Replicase polyprotein 1ab 5.23983187 actual virus 147 Enzyme
1a Replicase polyprotein 1a 5.146501741 actual virus 101 Enzyme
VHL von Hippel-Lindau disease tumor suppressor 4.412667156 actualAndPredicted mammals 43 Unclassified protein
FURIN Furin 3.804257957 predicted mammals 169 Serine protease S8B subfamily
CRBN Protein cereblon 4.397967462 actualAndPredicted mammals 19 Unclassified protein
Sigmar1 Sigma non-opioid intracellular receptor 1 2.816706135 actualAndPredicted mammals 692 Membrane receptor, Other membrane protein
NR3C1 Glucocorticoid receptor 2.841753598 actualAndPredicted mammals 348 Nuclear hormone receptor subfamily 3 group C member 1
CYSLTR1 Cysteinyl leukotriene receptor 1 3.065313119 actualAndPredicted mammals 182 Leukotriene receptor
BRD4 Bromodomain-containing protein 4 2.729343003 actualAndPredicted mammals 218 Bromodomain
IL6R Interleukin-6 receptor subunit alpha 4.640871157 actual mammals 1 Membrane receptor, Secreted protein
JAK2 Tyrosine-protein kinase JAK2 2.364319566 actualAndPredicted mammals 328 Tyrosine protein kinase JakA family, Tyrosine protein kinase JakB family
TUBB Tubulin beta chain 2.879798395 actualAndPredicted mammals 92 Structural protein
JAK1 Tyrosine-protein kinase JAK1 2.409715954 actualAndPredicted mammals 195 Tyrosine protein kinase JakA family, Tyrosine protein kinase JakB family
JAK3 Tyrosine-protein kinase JAK3 2.312167295 actualAndPredicted mammals 197 Tyrosine protein kinase JakA family, Tyrosine protein kinase JakB family
Hdac2 Histone deacetylase 2 2.364636615 actualAndPredicted mammals 173 HDAC class I
FKBP1A Peptidyl-prolyl cis-trans isomerase FKBP1A 2.811545153 actualAndPredicted mammals 57 Isomerase
TBK1 Serine/threonine-protein kinase TBK1 2.492399882 actualAndPredicted mammals 113 Other protein kinase IKK family
ATP1A1 Sodium/potassium-transporting ATPase subunit alpha-1 3.00165687 actualAndPredicted mammals 25 Hydrolase, Sodium potassium ATPase

Predicted activities have been aggregated at the protein level into different scores attending to their potency, frequency of protein-molecule interactions, and specificity based on positive records vs total number of active records. Network graphs show all ChEMBL  interactions of predicted active molecules. Barcharts and scatter plots show the aggregated potency against SARS-CoV (SARS_Score) vs the number of distinct molecular interactions for each protein (expressed as logged degree). Most interesting proteins attending to any of these values have been flagged in the scatter plots. Additional details as described in respective captions.

And how are these  proteins linked to SARS pathways annotated in Reactome DB ranked by their combination of scores.

Log10(degree): logged number of interactions for each protein. SARS_Score: Aggregated score against coronavirus infection per protein. Size by Degree/CountOfScores represents the number of SARS active interactions vs total records per protein in ChEMBL.

Scatter plot flagging all ChEMBL proteins linked to SARS pathways annotated in Reactome DB. Note significant scores for SigmaR1, Jak & ROCK kinases, FURIN protease, viral replicases, FKBPs, histone deacetylase HDAC2, glucocorticoid receptor NR3C1, bromodomain protein BRD4, Ub-transference subunits like CRBN and VHL, leukotriene receptor CYSLTR1 and Interleukin-6 receptor.

Aggregated SARS scores at the protein level: Log10(degree): logged number of interactions for each protein. SARS_Score: Aggregated score against coronavirus infection per protein. Size by Degree/CountOfScores represents the number of SARS actiove interactions vs total records per protein in ChEMBL. Color by condition of elements involved in score aggregation; they can be built from actual, predicted values or a combination of both. Shape indicates the organism type as described in the legend.