P53 Target Identification

Selection of targets potentially involved in regulation of P53 expression.

By Jawahar Swaminathan and MSD staff at the European Bioinformatics Institute [Public domain], via Wikimedia CommonsIn this section, we will make 2 different approaches. 1st one is a simple correlation analysis between the actual and predicted P53 score and the  experimental activity of the molecule at each specific target. The P53 score is calculated aggregating data by molecule-target pairs in a variable called Avg(combinedP53PotencyValue) composed of existing experimental values and predicted values when there is  no experimental record. The potency of each molecule at the specific targets is represented by Avg(chemblActivityScoreC). The corresponding correlation coefficient between the two variables and the slope are calculated and used to select what activities at specific targets are more related to P53 activity. Then, a second selection based on potency at P53 (potency at target could be used as well) is applied to highlight most interesting targets (see dashboard below).

 

Correlation coefficient vs slope plot (left). Average potency at P53 vs number of events (right). Dots marked in the left chart appear in the right chart to produce correlation plots coming next.

 

Once selected best correlating targets with higher average potency at P53 expression assay, the correlation plots by target can be visualized. Next three charts show the P53 to target correlation plots for all sort of assays, protein based assays, and cell-based assays.

P53-target correlation plot. All sort of targets.

 

P53-target correlation plot. Protein targets.

 

P53-target correlation plot. Cellular targets.

 

Table containing 40 best correlating assays.

prefNameCountOfEventscountOfUniqueMoleculessloper2target_typeorganismCchemblActivityScoreCabsoluteSlope
Neuronal acetylcholine receptor; alpha2/beta2283-1.99194627116590.68093664758539PROTEIN COMPLEXHomo sapiens, Rattus norvegicus8.08714285714281.9919462711659
Yersinia pestis225-0.970460454495150.65723874046743ORGANISMYersinia pestis5.63106133214010.97046045449515
GABA-A receptor; alpha-6/beta-3/gamma-21851.1801575944380.73561690979704PROTEIN COMPLEXHomo sapiens6.71047979088011.180157594438
Cholecystokinin receptor1641.60326795356290.57841168386489PROTEIN FAMILYHomo sapiens, Rattus norvegicus4.958751.6032679535629
BHK-2117120.67915908194060.72798970384539CELL-LINECricetulus griseus5.09277735294120.6791590819406
Cytochrome P450 2A574-0.529602678773750.77395217932381SINGLE PROTEINMus musculus5.23340286085940.52960267877375
Col219150.52024540510210.73623941631513CELL-LINEHomo sapiens5.40597956503490.5202454051021
WI-38 VA131340.463879376360180.63214138240056CELL-LINEHomo sapiens7.23477484615380.46387937636018
Plasmodium falciparum D6881.28977882811720.62294955990161ORGANISMPlasmodium falciparum D66.00345551.2897788281172
NCI-H166615150.67093042803680.6247410134345CELL-LINEHomo sapiens5.0372334839320.6709304280368
Sigma 2 receptor308-1.55277705238330.76671924587314UNKNOWNNotRecorded7.4181.5527770523833
CHO-AA81591.40645248209890.64661057001673CELL-LINECricetulus griseus5.10615806666671.4064524820989
Leukotriene B4 receptor 1940.69193351244270.73956478016104SINGLE PROTEINHomo sapiens, Mus musculus, Rattus norvegicus6.98527866666670.6919335124427
20081590.827934731979930.71656774107575CELL-LINEHomo sapiens5.17354260.82793473197993
J774.21260.620111082922390.62748284405509CELL-LINENotRecorded6.62364066288830.62011108292239
Arginase64-0.49715041788840.86181720580406SINGLE PROTEINLeishmania amazonensis5.54166666666670.4971504178884
CV-1770.637617326956510.62690491683738CELL-LINEChlorocebus aethiops5.1538250.63761732695651
YOSHIDA440.601509734201290.60574764230379CELL-LINERattus norvegicus6.4445120.60150973420129
1A9/ptx-10740.435089774389930.89147812599399CELL-LINEHomo sapiens5.63347257142860.43508977438993
Aspergillus oryzae1540.709737716307820.80624536987171ORGANISMAspergillus oryzae5.00229840.70973771630782
Trametes versicolor440.880260131062660.55792481431984ORGANISMTrametes versicolor5.1360470.88026013106266
Epoxide hydrolase 124140.818464762517240.6797777122813SINGLE PROTEINHomo sapiens, Mus musculus, Rattus norvegicus6.2003836250.81846476251724
Herpes simplex virus (type 1 / strain F)85-1.44495586222480.8023231333661ORGANISMHerpes simplex virus (type 1 / strain F)5.456050751.4449558622248
Fatty acid binding protein intestinal550.514842026293180.81576521587584SINGLE PROTEINHomo sapiens4.9180.51484202629318
Monoclonal antibody (mAb)1461.36197902835120.72244766258702UNKNOWNNotRecorded5.27785714285711.3619790283512
Brain adenylate cyclase 1750.633884647010990.62676353182922SINGLE PROTEINHomo sapiens5.27009428571430.63388464701099
Cell line1552.21940763493270.60893063445684CELL-LINEHomo sapiens6.62671922.2194076349327
Capnocytophaga ochracea44-1.5295232990090.94300960988513ORGANISMCapnocytophaga ochracea5.77995351.529523299009
Lactobacillus plantarum137-1.15207932707790.64886052947487ORGANISMLactobacillus plantarum5.06260984615391.1520793270779
Metabotropic glutamate receptor 1540.696126343236960.83512692337511SINGLE PROTEINHomo sapiens, Rattus norvegicus5.0180.69612634323696
Phosphodiesterase 4D1150.813365012848520.93512399568661SINGLE PROTEINHomo sapiens6.02513490909090.81336501284852
SCC-71260.711828202714740.65182834073058CELL-LINEMus musculus5.43938991666670.71182820271474
CCRF-HSB-2940.667438991422950.94897260054745CELL-LINEHomo sapiens6.09749955555560.66743899142295
C-C chemokine receptor type 8851.22507752986140.88405013972394SINGLE PROTEINHomo sapiens5.0251.2250775298614
Solute carrier organic anion transporter family member 1C1650.99275604525220.75197767620267SINGLE PROTEINHomo sapiens, Mus musculus5.63346216666670.9927560452522
CpG DNA methylase770.735709056379850.72620334667934SINGLE PROTEINSpiroplasma monobiae6.81857142857140.73570905637985
Bipolaris maydis540.564267127481580.804923180736ORGANISMCochliobolus heterostrophus5.71471640.56426712748158
Anopheles stephensi541.66070789676190.87572195360614ORGANISMAnopheles stephensi5.72759321.6607078967619
UDP-galactose 4-epimerase44-1.0315872000660.57251908396947SINGLE PROTEINTrypanosoma brucei5.3751.031587200066
Baculoviral IAP repeat-containing protein 2332.89382579699680.98409674480245SINGLE PROTEINHomo sapiens8.02666666666672.8938257969968
The table is composed of targets selected as depicted in the dual selection chart. Slope>0.4 and R2>0.57 in more than 3 or 4 distinct molecules having a potency score greater than 5.

 

Second approach joines P53-active molecule-target pairs into single molecular targets, calculating different P53 scores based on the results obtained with different predictive algorithms, and a target score, which is the result of the average potency at target of the P53 active compounds (actual and predicted).

When the P53 active molecule-target pairs are aggregated by target, a plot of the best scored targets can also be obtained to select protein targets with higher probability of inducing P53 expression:

Target score vs number of records per target.

 

Charts below shows the target selection by target score (bottom-right) with the values aggregated by target for the decision trees rate of predicted activity (countRatioRPart), random forests binomial (countRatioRF) and random forests regression (combinedPredictionScore).

 

Targets predicted to be involved in P53 expression

targetNameCountActualCountPredictedp53ScorePredictedActualp53ScorePredictedtargetScorecountRatioRpartcountRatioRFcountRatioAvgRpartRFcombinedPredictionScoreAvg(avgPredIndexcountTotalcountMoleculesMostCommon(uniprot)MostCommon(proteinName)MostCommon(Protein names)MostCommon(Gene names)MostCommon(targetName)UniqueConcatenate(kindOfValue) fororganism(s)kindOfValue
ANPRC0225.7223301055.7223301058.3775110.95454545512.426087398.2710797323322P17342Atrial natriuretic peptide receptorAtrial natriuretic peptide receptor 3 (Atrial natriuretic peptide clearance receptor) (Atrial natriuretic peptide receptor type C) (ANP-C) (ANPR-C) (NPR-C)NPR3 ANPRC C5orf23 NPRCANPRCpredictedHomo sapiens (Human)predicted
CATC16872.6439325342.6440810617.56434432410.0813953490.5406976742.3556330994.485962007744688P53634Dipeptidyl peptidase IDipeptidyl peptidase 1 (EC 3.4.14.1) (Cathepsin C) (Cathepsin J) (Dipeptidyl peptidase I) (DPP-I) (DPPI) (Dipeptidyl transferase) [Cleaved into: Dipeptidyl peptidase 1 exclusion domain chain (Dipeptidyl peptidase I exclusion domain chain); Dipeptidyl peptidase 1 heavy chain (Dipeptidyl peptidase I heavy chain); Dipeptidyl peptidase 1 light chain (Dipeptidyl peptidase I light chain)]CTSC CPPICATCactual, predictedBos taurus (Bovine), Homo sapiens (Human)actual and predicted
CRFR20795.2787212585.2787212587.638239823010.53.9590409435.0929070868979Q13324Corticotropin releasing factor receptor 2Corticotropin-releasing factor receptor 2 (CRF-R-2) (CRF-R2) (CRFR-2) (Corticotropin-releasing hormone receptor 2) (CRH-R-2) (CRH-R2)CRHR2 CRF2R CRH2RCRFR2predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)predicted
DHSO7852.9390929762.9320295396.36344836310.0851449280.5425724642.6709208444.59684741710592Q00796Sorbitol dehydrogenaseSorbitol dehydrogenase (EC 1.1.1.14) (L-iditol 2-dehydrogenase)SORDDHSOactual, predicted, predictedHomo sapiens (Human), Ovis aries (Sheep), Rattus norvegicus (Rat)actual and predicted
CDK41519594.2137663654.2137663656.6128083940.99949057610.5904440483.1603247744.92917964122341963P11802CDK4/Cyclin D3Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) (PSK-J3)CDK4CDK4actual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse)actual and predicted
EDNRA44719893.6835577183.6835577186.71975316610.6428571430.8214285716.6505992726.70404304936192436P25101Endothelin receptor ET-AEndothelin-1 receptor (Endothelin receptor type A) (ET-A) (ETA-R) (hET-AR)EDNRA ETA ETRAEDNRAactual, predicted, predictedBos taurus (Bovine), Homo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat), Sus scrofa (Pig)actual and predicted
PD2R232463.241995533.2423902357.9286176840.0120481930.9745649260.493306562.4287580684.369375574279249Q9Y5Y4G protein-coupled receptor 44Prostaglandin D2 receptor 2 (Chemoattractant receptor-homologous molecule expressed on Th2 cells) (G-protein coupled receptor 44) (CD antigen CD294)PTGDR2 CRTH2 DL1R GPR44PD2R2actual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
GBRA5174573.0577656633.0592880787.94428424310.4392284290.7041274894.298831885.7134384818592459P31644GABA receptor alpha-5 subunitGamma-aminobutyric acid receptor subunit alpha-5 (GABA(A) receptor subunit alpha-5)GABRA5GBRA5actual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
GRAB1222.9334409892.8901714686.66608695710.1304347830.5652173913.0152187144.7459296052523P10144Granzyme BGranzyme B (EC 3.4.21.79) (C11) (CTLA-1) (Cathepsin G-like 1) (CTSGL1) (Cytotoxic T-lymphocyte proteinase 2) (Lymphocyte protease) (Fragmentin-2) (Granzyme-2) (Human lymphocyte protein) (HLP) (SECT) (T-cell serine protease 1-3E)GZMB CGL1 CSPB CTLA1 GRBGRABactual, predictedHomo sapiens (Human)actual and predicted
RENI07763.864964813.864964817.24020306800.855884880.427942442.509961414.1412712031051776P00797ReninRenin (EC 3.4.23.15) (Angiotensinogenase)RENRENIpredictedCallithrix jacchus (White-tufted-ear marmoset), Homo sapiens (Human), Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), Rattus norvegicus (Rat)predicted
ADA1B1314003.685125223.6772753196.6578805570.9912553270.5813492060.7091078865.1623866545.94398353916761408P35368Adrenergic receptor alphaAlpha-1B adrenergic receptor (Alpha-1B adrenoreceptor) (Alpha-1B adrenoceptor)ADRA1BADA1Bactual, predicted, predictedHomo sapiens (Human), Mesocricetus auratus (Golden hamster), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
PCP0953.2745131013.2745131016.9323321830.3578947370.7157894740.5368421052.8007940684.67045173510895P42785Lysosomal Pro-X carboxypeptidaseLysosomal Pro-X carboxypeptidase (EC 3.4.16.2) (Angiotensinase C) (Lysosomal carboxypeptidase C) (Proline carboxypeptidase) (Prolylcarboxypeptidase) (PRCP)PRCP PCPPCPpredictedHomo sapiens (Human), Mus musculus (Mouse)predicted
PHKG22610172.9398638872.9398638876.7700392160.98705656810.5327021412.2533977894.40513479214241043P15735Phosphorylase kinasePhosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT) (PHK-gamma-T) (EC 2.7.11.19) (PSK-C3) (Phosphorylase kinase subunit gamma-2)PHKG2PHKG2actual, predicted, predictedHomo sapiens (Human)actual and predicted
SC6A245238783.0573890963.0558863628.680.99270867710.662595324.0889421785.43643183562614330P23975Monoamine transporters; Norepinephrine & dopamineSodium-dependent noradrenaline transporter (Norepinephrine transporter) (NET) (Solute carrier family 6 member 2)SLC6A2 NAT1 NET1 SLC6A5SC6A2actual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse)actual and predicted
CDK12413572.9033298122.9033298127.110903316110.5956130822.9910980144.89842288632981381P06493CDK1/Cyclin ACyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)CDK1 CDC2 CDC28A CDKN1 P34CDC2CDK1actual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)actual and predicted
CDK23130153.1870020433.1670245718.323560627110.5981550582.9143281054.88653015742863046P24941CDK2/Cyclin ACyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)CDK2 CDKN2CDK2actual, predicted, predictedHomo sapiens (Human)actual and predicted
DHI174893.0593623483.0578631716.6967707860.200589330.8397177420.5201535362.551499294.487477689634496P2884511-beta-hydroxysteroid dehydrogenase 1Corticosteroid 11-beta-dehydrogenase isozyme 1 (EC 1.1.1.146) (11-beta-hydroxysteroid dehydrogenase 1) (11-DH) (11-beta-HSD1) (Short chain dehydrogenase/reductase family 26C member 1)HSD11B1 HSD11 HSD11L SDR26C1DHI1actual, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
HYES112613.2411352133.244953597.1585077930.1479779410.8750.5114889712.6761968414.490304875342272P34913Epoxide hydrataseBifunctional epoxide hydrolase 2 [Includes: Cytosolic epoxide hydrolase 2 (CEH) (EC 3.3.2.10) (Epoxide hydratase) (Soluble epoxide hydrolase) (SEH); Lipid-phosphate phosphatase (EC 3.1.3.76)]EPHX2HYESactual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
CRFR1011083.5773161483.5773161487.31209255600.9954873650.4977436822.6714803334.51072993111661108P34998Corticotropin releasing factor receptor 1Corticotropin-releasing factor receptor 1 (CRF-R-1) (CRF-R1) (CRFR-1) (Corticotropin-releasing hormone receptor 1) (CRH-R-1) (CRH-R1)CRHR1 CRFR CRFR1 CRHRCRFR1predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)predicted
PPARG41645856.9751895886.9751895889.668651813110.6970720725.2313921915.65839652985385001P37231PPAR alpha/gammaPeroxisome proliferator-activated receptor gamma (PPAR-gamma) (Nuclear receptor subfamily 1 group C member 3)PPARG NR1C3PPARGactual, actual, predicted, predictedCanis lupus familiaris (Dog) (Canis familiaris), Homo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
IL24153.5500710033.2791106177.31789473710.2105263160.6052631584.1488015795.218444722019P60568Interleukin-2Interleukin-2 (IL-2) (T-cell growth factor) (TCGF) (Aldesleukin)IL2IL2actual, predictedHomo sapiens (Human), Mus musculus (Mouse)actual and predicted
CNR2919483.5677685713.5648839327.9853846150.6968504710.7692307690.6923076924.7690734555.80464080623291957P34972Cannabinoid CB2 receptorCannabinoid receptor 2 (CB-2) (CB2) (hCB2) (CX5)CNR2 CB2A CB2BCNR2actual, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
GBRA4174354.2531505494.2531505496.940514998110.7041274894.298831885.7134384818592452P48169GABA receptor alpha-4 subunitGamma-aminobutyric acid receptor subunit alpha-4 (GABA(A) receptor subunit alpha-4)GABRA4GBRA4actual, predicted, predictedBos taurus (Bovine), Homo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
PSN11545933.5375764993.5375764996.51310707110.3948087430.6974043724.8819048445.828554644148504608P49768Gamma-secretasePresenilin-1 (PS-1) (EC 3.4.23.-) (Protein S182) [Cleaved into: Presenilin-1 NTF subunit; Presenilin-1 CTF subunit; Presenilin-1 CTF12 (PS1-CTF12)]PSEN1 AD3 PS1 PSNL1PSN1actual, predictedHomo sapiens (Human)actual and predicted
PE2R435992.9961047582.9940607726.4779958590.998338870.24637320.6223560353.4591264665.147741822983602P35408Prostanoid EP4 receptorProstaglandin E2 receptor EP4 subtype (PGE receptor EP4 subtype) (PGE2 receptor EP4 subtype) (Prostanoid EP4 receptor)PTGER4 PTGER2PE2R4actual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Oryctolagus cuniculus (Rabbit), Rattus norvegicus (Rat)actual and predicted
P2RX722683.0047201282.998679857.133094060.0148148150.9925925930.5037037042.2953137464.359598067315270Q99572P2X purinoceptor 7P2X purinoceptor 7 (P2X7) (ATP receptor) (P2Z receptor) (Purinergic receptor)P2RX7P2RX7actual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
P2RY11813.6989640013.6969499156.8108333330.373983740.686991870.5304878053.2712877384.76957336610682P47900Purinergic receptor P2Y1P2Y purinoceptor 1 (P2Y1) (ATP receptor) (Purinergic receptor)P2RY1P2RY1actual, predictedHomo sapiens (Human), Meleagris gallopavo (Wild turkey), Rattus norvegicus (Rat)actual and predicted
PK3CA2651473.1680029133.1680029137.12974820.99632708310.5387173172.318865894.46863605468335173P42336PI3-kinase class IPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase subunit alpha) (PI3K-alpha) (PI3Kalpha) (PtdIns-3-kinase subunit alpha) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha) (PtdIns-3-kinase subunit p110-alpha) (p110alpha) (Phosphoinositide-3-kinase catalytic alpha polypeptide) (Serine/threonine protein kinase PIK3CA) (EC 2.7.11.1)PIK3CAPK3CAactual, predicted, predictedBos taurus (Bovine), Homo sapiens (Human), Mus musculus (Mouse)actual and predicted
P85A12053.1680029133.1680029137.1297482110.5454545452.4224085714.456202928636205P27986PI3-kinase class IPhosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha)PIK3R1 GRB1P85Aactual, predicted, predictedHomo sapiens (Human)actual and predicted
CASR210782.7449224972.7437244836.53750386910.1018132720.5509066362.5190873674.58768507112381080P41180Calcium sensing receptorExtracellular calcium-sensing receptor (CaR) (CaSR) (hCasR) (Parathyroid cell calcium-sensing receptor 1) (PCaR1)CASR GPRC2A PCAR1CASRactual, predicted, predictedBos taurus (Bovine), Homo sapiens (Human), Rattus norvegicus (Rat)actual and predicted
BACE201294.2489892284.2489892287.032800.840.422.7616926834.216329743130129Q9Y5Z0Beta secretase 2Beta-secretase 2 (EC 3.4.23.45) (Aspartic-like protease 56 kDa) (Aspartyl protease 1) (ASP1) (Asp 1) (Beta-site amyloid precursor protein cleaving enzyme 2) (Beta-site APP cleaving enzyme 2) (Down region aspartic protease) (DRAP) (Memapsin-1) (Membrane-associated aspartic protease 1) (Theta-secretase)BACE2 AEPLC ALP56 ASP21 CDA13 UNQ418/PRO852BACE2predictedHomo sapiens (Human), Rattus norvegicus (Rat)predicted
NPY5R32833.5305114253.5305114256.6790214420.1048951050.8986013990.5017482522.7049256664.521825487301286Q15761Neuropeptide Y receptor type 5Neuropeptide Y receptor type 5 (NPY5-R) (NPY-Y5 receptor) (NPYY5-R) (Y5 receptor)NPY5R NPYR5NPY5Ractual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
MTP01033.6398586483.6398586487.7533382910.6990291260.8495145630.7742718455.7941131886.375098514113103P55157Microsomal triglyceride transfer protein large subunitMicrosomal triglyceride transfer protein large subunitMTTP MTPMTPpredictedHomo sapiens (Human)predicted
CCNA2228015.2518585625.2518585627.51110.5981550583.9388939225.0839528541305823P20248CDK1/Cyclin ACyclin-A2 (Cyclin-A) (Cyclin A)CCNA2 CCN1 CCNACCNA2actual, predicted, predictedHomo sapiens (Human)actual and predicted
ACHA90285.7649020115.7649020116.7010.54.3236765085.2549673376428Q9UGM1Neuronal acetylcholine receptor protein alpha-9 subunitNeuronal acetylcholine receptor subunit alpha-9 (Nicotinic acetylcholine receptor subunit alpha-9) (NACHR alpha-9)CHRNA9 NACHRA9ACHA9predictedHomo sapiens (Human), Rattus norvegicus (Rat)predicted
ACM344925103.4950296953.4931493026.7610.6894586890.6844729344.637910245.72816279543272959P20309Muscarinic acetylcholine receptorMuscarinic acetylcholine receptor M3CHRM3ACM3actual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
VEGFA0354.844343264.844343266.7376061500.9142857140.4571428573.3648254824.6624001343535P15692Vascular endothelial growth factor AVascular endothelial growth factor A (VEGF-A) (Vascular permeability factor) (VPF)VEGFA VEGFVEGFApredictedHomo sapiens (Human)predicted
EDNRB11903.6835577183.6835577186.71975316610.9581151830.8214285716.6505992726.704043049207191P24530Endothelin receptor ET-BEndothelin receptor type B (ET-B) (ET-BR) (Endothelin receptor non-selective type)EDNRB ETRBEDNRBactual, predicted, predictedBos taurus (Bovine), Homo sapiens (Human), Mus musculus (Mouse), Oryctolagus cuniculus (Rabbit), Rattus norvegicus (Rat), Sus scrofa (Pig)actual and predicted
S5A101023.7477173493.7477173497.212038151110.8333333336.5585053616.804794672115102P18405Steroid 5-alpha-reductase3-oxo-5-alpha-steroid 4-dehydrogenase 1 (EC 1.3.1.22) (SR type 1) (Steroid 5-alpha-reductase 1) (S5AR 1)SRD5A1S5A1actual, predicted, predictedHomo sapiens (Human), Rattus norvegicus (Rat)actual and predicted
SCNNA2413.7045422953.479129087.40071428610.9444444440.9722222228.1245172117.7163289134242P37088Amiloride-sensitive sodium channel alpha-subunitAmiloride-sensitive sodium channel subunit alpha (Alpha-NaCH) (Epithelial Na(+) channel subunit alpha) (Alpha-ENaC) (ENaCA) (Nonvoltage-gated sodium channel 1 subunit alpha) (SCNEA)SCNN1A SCNN1SCNNAactual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse)actual and predicted
SSR519665.2839476275.2839476278.013951641110.792485357.0142094426.5812330231096967P35346Somatostatin receptorSomatostatin receptor type 5 (SS-5-R) (SS5-R) (SS5R)SSTR5SSR5actual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
TRY133613.736069773.736069776.6086613960.077609890.9358108110.475847072.6989315984.4109776531137364P07477TrypsinTrypsin-1 (EC 3.4.21.4) (Beta-trypsin) (Cationic trypsinogen) (Serine protease 1) (Trypsin I) [Cleaved into: Alpha-trypsin chain 1; Alpha-trypsin chain 2]PRSS1 TRP1 TRY1 TRYP1TRY1actual, predicted, predictedBos taurus (Bovine), Homo sapiens (Human), Rattus norvegicus (Rat)actual and predicted
ITAL43184.677160164.677160166.906965128110.5970496893.507870125.003433388456322P20701Integrin alpha-L/beta-2 (LFA-1)Integrin alpha-L (CD11 antigen-like family member A) (Leukocyte adhesion glycoprotein LFA-1 alpha chain) (LFA-1A) (Leukocyte function-associated molecule 1 alpha chain) (CD antigen CD11a)ITGAL CD11AITALactual, predicted, predictedHomo sapiens (Human)actual and predicted
SSR219035.2839476275.2839476278.013951641110.8171367997.666115886.8294872351112904P30874Somatostatin receptorSomatostatin receptor type 2 (SS-2-R) (SS2-R) (SS2R) (SRIF-1)SSTR2SSR2actual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
ACE43553.4921044113.4921044116.6650.9173630450.4479166670.5402971223.0850075414.740423693428359P12821Angiotensin-converting enzymeAngiotensin-converting enzyme (ACE) (EC 3.2.1.-) (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (CD antigen CD143) [Cleaved into: Angiotensin-converting enzyme, soluble form]ACE DCP DCP1ACEactual, predicted, predictedHomo sapiens (Human), Oryctolagus cuniculus (Rabbit), Rattus norvegicus (Rat)actual and predicted
HDAC15287003.6016063563.6016063566.91579671210.5606936420.7803468215.7992955646.402847591369348752Q13547Histone deacetylaseHistone deacetylase 1 (HD1) (EC 3.5.1.98)HDAC1 RPD3L1HDAC1actual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
HDAC35287003.5605612213.5605612216.86245284910.5326086960.7663043485.7497414486.295549393369348752O15379Histone deacetylaseHistone deacetylase 3 (HD3) (EC 3.5.1.98) (RPD3-2) (SMAP45)HDAC3HDAC3actual, predictedHomo sapiens (Human), Rattus norvegicus (Rat)actual and predicted
CALCR4474423.6284251423.6276455229.19110.7716535436.4202149936.3538320031811889P30988Amylin receptor AMY1, CALCR/RAMP1Calcitonin receptor (CT-R)CALCRCALCRactual, predicted, predictedHomo sapiens (Human), Rattus norvegicus (Rat)actual and predicted
AGTR1686553.8926333693.8926333697.50157841210.80.8576220227.2252541327.0150246011416655P30556Angiotensin II receptorType-1 angiotensin II receptor (AT1AR) (AT1BR) (Angiotensin II type-1 receptor) (AT1)AGTR1 AGTR1A AGTR1B AT2R1 AT2R1BAGTR1actual, predicted, predictedBos taurus (Bovine), Cavia porcellus (Guinea pig), Homo sapiens (Human), Oryctolagus cuniculus (Rabbit), Sus scrofa (Pig)actual and predicted
5HT2B46119623.6335858423.6335858426.20610288810.4792746110.7163212445.1693593765.98667023840222423P41595Serotonin (5-HT) receptor5-hydroxytryptamine receptor 2B (5-HT-2B) (5-HT2B) (Serotonin receptor 2B)HTR2B5HT2Bactual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
ITA2B02823.8318363473.8318363476.1994999360.24468085110.5041371162.8738772614.610612116626282P08514Integrin alpha-IIbIntegrin alpha-IIb (GPalpha IIb) (GPIIb) (Platelet membrane glycoprotein IIb) (CD antigen CD41) [Cleaved into: Integrin alpha-IIb heavy chain; Integrin alpha-IIb light chain, form 1; Integrin alpha-IIb light chain, form 2]ITGA2B GP2B ITGABITA2BpredictedHomo sapiens (Human)predicted
ADA1A1515583.685125223.6772753197.2408722350.9920231280.5813492060.7091078865.1623866545.94398353921091573P35348Adrenergic receptor alphaAlpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) (Alpha-adrenergic receptor 1c)ADRA1A ADRA1CADA1Aactual, predicted, predictedBos taurus (Bovine), Cavia porcellus (Guinea pig), Homo sapiens (Human), Mus musculus (Mouse), Oryctolagus cuniculus (Rabbit), Rattus norvegicus (Rat)actual and predicted
GBRB3174354.9788523594.9694796637.41243651710.7471264370.71255.2446941145.988348168592452P28472GABA receptor beta-3 subunitGamma-aminobutyric acid receptor subunit beta-3 (GABA(A) receptor subunit beta-3)GABRB3GBRB3actual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
SSR415525.2839476275.2839476278.0139516410.10307414110.5036166373.962960725.094649209615553P31391Somatostatin receptorSomatostatin receptor type 4 (SS-4-R) (SS4-R) (SS4R)SSTR4SSR4actual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
GNRHR03344.1129562874.1129562877.6770569640.0014970060.9940119760.4977544913.0755230524.689348702625334P30968Gonadotropin-releasing hormone receptorGonadotropin-releasing hormone receptor (GnRH receptor) (GnRH-R)GNRHR GRHRGNRHRpredictedHomo sapiens (Human), Macaca mulatta (Rhesus macaque), Rattus norvegicus (Rat)predicted
S5A211563.7477173493.7477173497.685644796110.8333333336.5585053616.804794672189157P31213Steroid 5-alpha-reductase3-oxo-5-alpha-steroid 4-dehydrogenase 2 (EC 1.3.1.22) (5 alpha-SR2) (SR type 2) (Steroid 5-alpha-reductase 2) (S5AR 2) (Type II 5-alpha reductase)SRD5A2S5A2actual, predicted, predictedHomo sapiens (Human), Rattus norvegicus (Rat)actual and predicted
THA55033.617583963.617583967.9960685880.95078740210.5840048242.9717546474.83560047717508P10827Thyroid hormone receptorThyroid hormone receptor alpha (Nuclear receptor subfamily 1 group A member 1) (V-erbA-related protein 7) (EAR-7) (c-erbA-1) (c-erbA-alpha)THRA EAR7 ERBA1 NR1A1 THRA1 THRA2THAactual, predicted, predictedHomo sapiens (Human)actual and predicted
ACM145626903.4950296953.4931493029.3610.6894586890.754.637910245.89873892349113146P11229Muscarinic acetylcholine receptorMuscarinic acetylcholine receptor M1CHRM1ACM1actual, predicted, predictedDrosophila melanogaster (Fruit fly), Homo sapiens (Human), Macaca mulatta (Rhesus macaque), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
VGFR147328553.8299964363.8316440846.3699924460.9987730370.5699845680.7340663585.740741466.17044119948623328P17948Vascular endothelial growth factor receptorVascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase FRT) (Tyrosine-protein kinase receptor FLT) (FLT) (Vascular permeability factor receptor)FLT1 FLT FRT VEGFR1VGFR1actual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse)actual and predicted
ITA422423.4227096483.4227096487.5761457370.0555555560.9722222220.5119047622.5312688444.45404852668242P13612Integrin alpha-4Integrin alpha-4 (CD49 antigen-like family member D) (Integrin alpha-IV) (VLA-4 subunit alpha) (CD antigen CD49d)ITGA4 CD49DITA4actual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse)actual and predicted
KCJ1131504.0398516334.0398516336.707126250.38095238110.559523813.1274945864.762611919422150Q14654Potassium channel, inwardly rectifying, subfamily J, member 11ATP-sensitive inward rectifier potassium channel 11 (IKATP) (Inward rectifier K(+) channel Kir6.2) (Potassium channel, inwardly rectifying subfamily J member 11)KCNJ11KCJ11actual, predicted, predictedHomo sapiens (Human), Rattus norvegicus (Rat)actual and predicted
V1AR45314014.0093161684.0093161686.4247074370.99352750810.7026199935.1113242365.79452406431141854P37288Vasopressin V1 receptorVasopressin V1a receptor (V1aR) (AVPR V1a) (Antidiuretic hormone receptor 1a) (Vascular/hepatic-type arginine vasopressin receptor)AVPR1A AVPR1V1ARactual, predicted, predictedHomo sapiens (Human), Microtus ochrogaster (Prairie vole), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
FOLH10534.3696414394.3696414396.700234765010.53.2772310794.789880489353Q04609Glutamate carboxypeptidase IIGlutamate carboxypeptidase 2 (EC 3.4.17.21) (Cell growth-inhibiting gene 27 protein) (Folate hydrolase 1) (Folylpoly-gamma-glutamate carboxypeptidase) (FGCP) (Glutamate carboxypeptidase II) (GCPII) (Membrane glutamate carboxypeptidase) (mGCP) (N-acetylated-alpha-linked acidic dipeptidase I) (NAALADase I) (Prostate-specific membrane antigen) (PSM) (PSMA) (Pteroylpoly-gamma-glutamate carboxypeptidase)FOLH1 FOLH NAALAD1 PSM PSMA GIG27FOLH1predictedHomo sapiens (Human)predicted
5HT3A157703.6186427313.6186427318.710.50.755.6927206486.2062142441490785P46098Serotonin 3 (5-HT3) receptor5-hydroxytryptamine receptor 3A (5-HT3-A) (5-HT3A) (5-hydroxytryptamine receptor 3) (5-HT-3) (5-HT3R) (Serotonin receptor 3A) (Serotonin-gated ion channel receptor)HTR3A 5HT3R HTR35HT3Aactual, predicted, predictedCavia porcellus (Guinea pig), Homo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
FKB1A162713.135295383.1269562356.9854074080.9773519160.6431718060.5932055753.2169057114.95181827342287P62942FK506-binding protein 1APeptidyl-prolyl cis-trans isomerase FKBP1A (PPIase FKBP1A) (EC 5.2.1.8) (12 kDa FK506-binding protein) (12 kDa FKBP) (FKBP-12) (Calstabin-1) (FK506-binding protein 1A) (FKBP-1A) (Immunophilin FKBP12) (Rotamase)FKBP1A FKBP1 FKBP12FKB1Aactual, predictedHomo sapiens (Human)actual and predicted
NMDE243483.000277613.000277616.81260180310.3881899350.6884131494.048698485.5895135323360352Q13224Glutamate NMDA receptor; GRIN1/GRIN2BGlutamate receptor ionotropic, NMDA 2B (GluN2B) (Glutamate [NMDA] receptor subunit epsilon-2) (N-methyl D-aspartate receptor subtype 2B) (NMDAR2B) (NR2B) (N-methyl-D-aspartate receptor subunit 3) (NR3) (hNR3)GRIN2B NMDAR2BNMDE2actual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
ITB102425.8523091775.8523091777.5761457370.02995867810.5005165293.6019411284.537834402668242P05556Fibronectin receptor (Integrin alpha-5/beta-1 and alpha-V/beta-3)Integrin beta-1 (Fibronectin receptor subunit beta) (Glycoprotein IIa) (GPIIA) (VLA-4 subunit beta) (CD antigen CD29)ITGB1 FNRB MDF2 MSK12ITB1predictedHomo sapiens (Human)predicted
RAF12712933.4103431313.4103431316.16690480.98497474710.5560311452.5875178654.61456164616301320P04049Serine/threonine-protein kinase RAFRAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)RAF1 RAFRAF1actual, predicted, predictedHomo sapiens (Human)actual and predicted
ADA084.1709988034.1709988036.7912500.9166666670.4583333332.87855954.44588849138P00813Adenosine deaminaseAdenosine deaminase (EC 3.5.4.4) (Adenosine aminohydrolase)ADA ADA1ADAactual, predicted, predictedBos taurus (Bovine), Homo sapiens (Human), Mus musculus (Mouse)actual and predicted
SC6A445552533.1004346413.0991284218.14250.98623851210.6605701194.0574086365.43727900479225708P31645Serotonin and norepinephrine transporters (SERT/NET)Sodium-dependent serotonin transporter (SERT) (5HT transporter) (5HTT) (Solute carrier family 6 member 4)SLC6A4 HTT SERTSC6A4actual, predicted, predictedHomo sapiens (Human), Macaca mulatta (Rhesus macaque), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
SSR105085.2839476275.2839476278.013951641010.53.962960725.094649209583508P30872Somatostatin receptorSomatostatin receptor type 1 (SS-1-R) (SS1-R) (SS1R) (SRIF-2)SSTR1SSR1predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)predicted
ADA1D44514483.685125223.6772753196.6578805570.9928373890.5813492060.7091078865.1623866545.94398353930131893P25100Adrenergic receptor alphaAlpha-1D adrenergic receptor (Alpha-1A adrenergic receptor) (Alpha-1D adrenoreceptor) (Alpha-1D adrenoceptor) (Alpha-adrenergic receptor 1a)ADRA1D ADRA1AADA1Dactual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
CA2D10482.5984513882.5984513886.643333333010.51.9488385414.1994837964848P54289Voltage-gated calcium channel alpha2/delta subunit 1Voltage-dependent calcium channel subunit alpha-2/delta-1 (Voltage-gated calcium channel subunit alpha-2/delta-1) [Cleaved into: Voltage-dependent calcium channel subunit alpha-2-1; Voltage-dependent calcium channel subunit delta-1]CACNA2D1 CACNL2A CCHL2A MHS3CA2D1predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)predicted
V1BR61644.3051309334.3039299526.424707437010.53.22884824.768376978284170P47901Vasopressin V1 receptorVasopressin V1b receptor (V1bR) (AVPR V1b) (AVPR V3) (Antidiuretic hormone receptor 1b) (Vasopressin V3 receptor)AVPR1B AVPR3 VPR3V1BRactual, predicted, predictedHomo sapiens (Human), Rattus norvegicus (Rat)actual and predicted
OPRD48549574.1441194913.9991560779.1624034380.99142472110.7247474755.3535286796.00533268287905442P41143Delta opioid receptorDelta-type opioid receptor (D-OR-1) (DOR-1)OPRD1 OPRDOPRDactual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
PPARA6728313.5402724133.5402724139.6686518130.98210853910.5980541573.008119324.91180199145262898Q07869PPAR alpha/gammaPeroxisome proliferator-activated receptor alpha (PPAR-alpha) (Nuclear receptor subfamily 1 group C member 1)PPARA NR1C1 PPARPPARAactual, predicted, predictedCanis lupus familiaris (Dog) (Canis familiaris), Homo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
2B110134.0121457254.0121457256.88982282010.53.0091092944.6707152422613P04229HLA class II histocompatibility antigen DRB1-1HLA class II histocompatibility antigen, DRB1-1 beta chain (MHC class II antigen DRB1*1) (DR-1) (DR1)HLA-DRB12B11predictedHomo sapiens (Human)predicted
DPP4810263.1022742873.1012234216.5971211390.6108094030.4360958190.5234526112.5702970064.52377550411771034P27487Dipeptidyl peptidase IVDipeptidyl peptidase 4 (EC 3.4.14.5) (ADABP) (Adenosine deaminase complexing protein 2) (ADCP-2) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (TP103) (CD antigen CD26) [Cleaved into: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form); Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)]DPP4 ADCP2 CD26DPP4actual, predicted, predictedBos taurus (Bovine), Homo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat), Sus scrofa (Pig)actual and predicted
5HT1A3440193.405787923.405787926.75256261310.2677777780.6338888894.0384906115.36118856657104053P08908Serotonin (5-HT) receptor5-hydroxytryptamine receptor 1A (5-HT-1A) (5-HT1A) (G-21) (Serotonin receptor 1A)HTR1A ADRB2RL1 ADRBRL15HT1Aactual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
NEP1473.1149096283.1011993486.82007850.04166666710.5208333332.7582440884.5105254325148P08473NeprilysinNeprilysin (EC 3.4.24.11) (Atriopeptidase) (Common acute lymphocytic leukemia antigen) (CALLA) (Enkephalinase) (Neutral endopeptidase 24.11) (NEP) (Neutral endopeptidase) (Skin fibroblast elastase) (SFE) (CD antigen CD10)MME EPNNEPactual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Oryctolagus cuniculus (Rabbit), Rattus norvegicus (Rat), Sus scrofa (Pig)actual and predicted
MTR1A28632.9842050472.9830904957.2017435810.9865969270.2041516840.5953743053.1299407594.9638970511181865P48039Melatonin receptorMelatonin receptor type 1A (Mel-1A-R) (Mel1a receptor)MTNR1AMTR1Aactual, predictedGallus gallus (Chicken), Homo sapiens (Human)actual and predicted
THB6056493.88241093.7415930677.9960685880.53480861210.6489832544.9440924325.62069199117041254P10828Thyroid hormone receptorThyroid hormone receptor beta (Nuclear receptor subfamily 1 group A member 2) (c-erbA-2) (c-erbA-beta)THRB ERBA2 NR1A2 THR1THBactual, predicted, predictedHomo sapiens (Human)actual and predicted
VGFR33015123.8299964363.8316440846.3699924460.9907047120.5699845680.7340663585.740741466.17044119919951542P35916Vascular endothelial growth factor receptorVascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like tyrosine kinase 4) (FLT-4) (Tyrosine-protein kinase receptor FLT4)FLT4 VEGFR3VGFR3actual, predictedHomo sapiens (Human)actual and predicted
GBRA1174353.5886587873.5886587877.464712143110.7420634925.3404596216.0754218598592452P14867GABA A receptor alpha-1/beta-1/gamma-2Gamma-aminobutyric acid receptor subunit alpha-1 (GABA(A) receptor subunit alpha-1)GABRA1GBRA1actual, predicted, predictedBos taurus (Bovine), Homo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
PDE4A3337653.5333146613.5325565927.2447172270.4616019820.890.5710461653.4766389974.98474598547313798P27815Phosphodiesterase 4cAMP-specific 3',5'-cyclic phosphodiesterase 4A (EC 3.1.4.53) (DPDE2) (PDE46)PDE4A DPDE2PDE4Aactual, predicted, predictedCavia porcellus (Guinea pig), Homo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
5HT1D42903.405787923.405787927.44763642110.812925170.6338888894.0384906115.361188566510294P28221Serotonin (5-HT) receptor5-hydroxytryptamine receptor 1D (5-HT-1D) (5-HT1D) (Serotonin 1D alpha receptor) (5-HT-1D-alpha) (Serotonin receptor 1D)HTR1D HTR1DA HTRL5HT1Dactual, predicted, predictedCavia porcellus (Guinea pig), Homo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat), Sus scrofa (Pig)actual and predicted
5HT2C46436713.6335858423.6335858426.20610288810.4792746110.7163212445.1693593765.98667023862274135P28335Serotonin (5-HT) receptor5-hydroxytryptamine receptor 2C (5-HT-2C) (5-HT2C) (5-HTR2C) (5-hydroxytryptamine receptor 1C) (5-HT-1C) (5-HT1C) (Serotonin receptor 2C)HTR2C HTR1C5HT2Cactual, predicted, predictedCanis lupus familiaris (Dog) (Canis familiaris), Homo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
GLR12523.5891750643.5891750647.01912271600.9762845850.4881422922.6309095544.450673638333253P47871Glucagon receptorGlucagon receptor (GL-R)GCGRGLRactual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
ANPRA0635.7223301055.7223301057.83110.95454545512.426087398.2710797326363P16066Atrial natriuretic peptide receptorAtrial natriuretic peptide receptor 1 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type A) (ANP-A) (ANPR-A) (NPR-A) (Guanylate cyclase A) (GC-A)NPR1 ANPRAANPRApredictedHomo sapiens (Human)predicted
AA2AR46051683.1311921483.1179372246.9355420110.97757048110.5817695113.1148084.84238029873565628P29274Adenosine A2 receptorAdenosine receptor A2aADORA2A ADORA2AA2ARactual, predicted, predictedCavia porcellus (Guinea pig), Homo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
SC6A345139063.0483015483.0470801978.680.99449162310.6580332944.0092531345.4029891463884357Q01959Dopamine transporterSodium-dependent dopamine transporter (DA transporter) (DAT) (Solute carrier family 6 member 3)SLC6A3 DAT1SC6A3actual, predicted, predictedHomo sapiens (Human), Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
OPRM49548124.1441194913.9589436588.030517826110.7247474755.3535286796.00533268283615307P35372CCR5/mu opioid receptor complexMu-type opioid receptor (M-OR-1) (MOR-1) (Mu opiate receptor) (Mu opioid receptor) (MOP) (hMOP)OPRM1 MOR1OPRMactual, actual, predicted, predictedBos taurus (Bovine), Cavia porcellus (Guinea pig), Homo sapiens (Human), Macaca mulatta (Rhesus macaque), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
SSR319125.2839476275.2839476278.013951641110.8019045887.151616866.6514432431268913P32745Somatostatin receptorSomatostatin receptor type 3 (SS-3-R) (SS3-R) (SS3R) (SSR-28)SSTR3SSR3actual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
OXYR62204.4143459774.3985098457.73869460300.9749262540.4874631273.2425637694.721202838285226P30559Oxytocin receptorOxytocin receptor (OT-R)OXTROXYRactual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
RXRA3467983.6472199183.6271498016.87046446710.4455827830.7223543285.5897500626.03143549522301144P19793RXR alpha/PPAR gammaRetinoic acid receptor RXR-alpha (Nuclear receptor subfamily 2 group B member 1) (Retinoid X receptor alpha)RXRA NR2B1RXRAactual, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
TA2R01312.9760989792.9760989796.41636249700.9923664120.4961832062.2123144194.299921034152131P21731Thromboxane A2 receptorThromboxane A2 receptor (TXA2-R) (Prostanoid TP receptor)TBXA2RTA2RpredictedHomo sapiens (Human), Rattus norvegicus (Rat)predicted
ABCC831504.0249154114.0249154117.8075010.53.0186865584.674971804422150Q09428Sulfonylurea receptor 1ATP-binding cassette sub-family C member 8 (Sulfonylurea receptor 1)ABCC8 HRINS SUR SUR1ABCC8actual, predicted, predictedHomo sapiens (Human), Rattus norvegicus (Rat)actual and predicted
PPIB1344.3484794964.3501338746.80114285710.6857142860.8428571438.5670587397.0685407843735P23284Cyclophilin BPeptidyl-prolyl cis-trans isomerase B (PPIase B) (EC 5.2.1.8) (CYP-S1) (Cyclophilin B) (Rotamase B) (S-cyclophilin) (SCYLP)PPIB CYPBPPIBactual, predictedHomo sapiens (Human)actual and predicted
KLK30314.4733680674.4733680676.777636348010.53.355026054.8244560224031P07288Prostate specific antigenProstate-specific antigen (PSA) (EC 3.4.21.77) (Gamma-seminoprotein) (Seminin) (Kallikrein-3) (P-30 antigen) (Semenogelase)KLK3 APSKLK3predictedHomo sapiens (Human)predicted
CXCR411364.4684476014.4684476016.6711132640.007299270.963503650.485401463.3023003534.725492266154137P61073C-X-C chemokine receptor type 4C-X-C chemokine receptor type 4 (CXC-R4) (CXCR-4) (FB22) (Fusin) (HM89) (LCR1) (Leukocyte-derived seven transmembrane domain receptor) (LESTR) (Lipopolysaccharide-associated protein 3) (LAP-3) (LPS-associated protein 3) (NPYRL) (Stromal cell-derived factor 1 receptor) (SDF-1 receptor) (CD antigen CD184)CXCR4CXCR4actual, predictedHomo sapiens (Human)actual and predicted
CCNT1141243.3442645443.34426454410.555110750.08695652210.5072463772.5081984084.448088181168138O60563CDK9/cyclin T1Cyclin-T1 (CycT1) (Cyclin-T)CCNT1CCNT1actual, predicted, predictedHomo sapiens (Human)actual and predicted
AA1R45645522.8951264962.8940279676.9355420110.96657015410.5849661063.1522011864.86481620274235008P30542Adenosine A1 receptorAdenosine receptor A1ADORA1AA1Ractual, predicted, predictedBos taurus (Bovine), Cavia porcellus (Guinea pig), Gallus gallus (Chicken), Homo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
VACHT01703.0810401383.0810401387.2115850290.9294117650.3803921570.6549019613.7827451415.393026451186170Q16572Vesicular acetylcholine transporterVesicular acetylcholine transporter (VAChT) (Solute carrier family 18 member 3)SLC18A3 VACHTVACHTactual, predicted, predictedHomo sapiens (Human), Rattus norvegicus (Rat), Tetronarce californica (Pacific electric ray) (Torpedo californica)actual and predicted
LIPC0184.1740228164.1740228166.86500.6666666670.3333333332.2238064593.6135631611818P11150Hepatic lipaseHepatic triacylglycerol lipase (HL) (Hepatic lipase) (EC 3.1.1.3) (Lipase member C)LIPC HTGLLIPCpredictedHomo sapiens (Human)predicted
PEPC093.7234023653.7234023656.292728344010.52.7925517744.57446745599P20142Pepsinogen CGastricsin (EC 3.4.23.3) (Pepsinogen C)PGCPEPCpredictedHomo sapiens (Human)predicted
KMO053.0851336073.0851336076.63700.80.41.777062583.69504453695O15229Kynurenine 3-monooxygenaseKynurenine 3-monooxygenase (EC 1.14.13.9) (Kynurenine 3-hydroxylase)KMOKMOpredictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)predicted
5HT4R45343.405787923.405787926.68553626210.2677777780.6338888894.0384906115.361188566962538Q13639Serotonin (5-HT) receptor5-hydroxytryptamine receptor 4 (5-HT-4) (5-HT4) (Serotonin receptor 4)HTR45HT4Ractual, predictedCavia porcellus (Guinea pig), Homo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
P2Y12311712.7475856522.7456402596.7290755540.9987223170.1051571940.5519397552.544701314.59546025317381174Q9H244Purinergic receptor P2Y12P2Y purinoceptor 12 (P2Y12) (ADP-glucose receptor) (ADPG-R) (P2T(AC)) (P2Y(AC)) (P2Y(cyc)) (P2Y12 platelet ADP receptor) (P2Y(ADP)) (SP1999)P2RY12 HORK3P2Y12actual, predictedHomo sapiens (Human), Rattus norvegicus (Rat)actual and predicted
HNMT263.472337863.4628978516.227510.50.756.0833991196.157445953128P50135Histamine N-methyltransferaseHistamine N-methyltransferase (HMT) (EC 2.1.1.8)HNMTHNMTactual, predicted, predictedCavia porcellus (Guinea pig), Homo sapiens (Human)actual and predicted
MTLR0244.0618696964.0618696967.17715277800.745370370.3726851852.2846439743.8385244673924O43193Motilin receptorMotilin receptor (G-protein coupled receptor 38)MLNR GPR38 MTLR MTLR1MTLRpredictedHomo sapiens (Human)predicted
CPNS10332.5415416882.5415416886.100940303010.51.9061562664.1805138963333P04632Calpain 1Calpain small subunit 1 (CSS1) (Calcium-activated neutral proteinase small subunit) (CANP small subunit) (Calcium-dependent protease small subunit) (CDPS) (Calcium-dependent protease small subunit 1) (Calpain regulatory subunit)CAPNS1 CAPN4 CAPNSCPNS1predictedHomo sapiens (Human), Sus scrofa (Pig)predicted
SUIS0133.4450313433.4450313436.79692307700.9230769230.4615384622.3658438164.2252668581613P14410Sucrase-isomaltaseSucrase-isomaltase, intestinal [Cleaved into: Sucrase (EC 3.2.1.48); Isomaltase (EC 3.2.1.10)]SISUISactual, predicted, predictedHomo sapiens (Human), Rattus norvegicus (Rat)actual and predicted
PRKDC52822.8326769672.8285176036.4088663630.7630662020.310104530.5365853662.5286198034.521461428290287P78527DNA-dependent protein kinaseDNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) (DNPK1) (p460)PRKDC HYRC HYRC1PRKDCactual, predictedHomo sapiens (Human)actual and predicted
PK3CB1714792.9779415752.9779415756.970.99298128310.5406082892.3747676994.48737934518001496P42338PI3-kinase class IPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (PI3-kinase subunit beta) (PI3K-beta) (PI3Kbeta) (PtdIns-3-kinase subunit beta) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta) (PtdIns-3-kinase subunit p110-beta) (p110beta)PIK3CB PIK3C1PK3CBactual, predicted, predictedHomo sapiens (Human), Rattus norvegicus (Rat)actual and predicted
NK3R01503.9929338853.9929338857.56568113700.9866666670.4933333332.9603884424.619866851208150P29371Neurokinin 3 receptorNeuromedin-K receptor (NKR) (NK-3 receptor) (NK-3R) (Neurokinin B receptor) (Tachykinin receptor 3)TACR3 NK3R TAC3RNK3RpredictedCavia porcellus (Guinea pig), Homo sapiens (Human), Rattus norvegicus (Rat)predicted
5HT7R2018173.405787923.405787926.5119948210.2677777780.6338888894.0384906115.36118856623771837P34969Serotonin (5-HT) receptor5-hydroxytryptamine receptor 7 (5-HT-7) (5-HT7) (5-HT-X) (Serotonin receptor 7)HTR75HT7Ractual, actual, predicted, predictedCavia porcellus (Guinea pig), Homo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
GALR215475.1164456345.0267736916.467984844010.53.8373342255.0388152119362O43603Galanin receptor 2Galanin receptor type 2 (GAL2-R) (GALR-2)GALR2 GALNR2GALR2actual, predictedHomo sapiens (Human)actual and predicted
ADCY50374.1559347094.1559347096.9893928110.8750.8333333337.5501833436.94086712535137O95622Adenylate cyclaseAdenylate cyclase type 5 (EC 4.6.1.1) (ATP pyrophosphate-lyase 5) (Adenylate cyclase type V) (Adenylyl cyclase 5) (AC5)ADCY5ADCY5actual, predicted, predictedHomo sapiens (Human), Rattus norvegicus (Rat)actual and predicted
ACM245024883.4950296953.4931493029.3610.6894586890.754.637910245.89873892342282938P08172Muscarinic acetylcholine receptorMuscarinic acetylcholine receptor M2CHRM2ACM2actual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat), Sus scrofa (Pig)actual and predicted
ROCK13218812.5844098072.5844098076.42107280.98719289110.5359383172.2460620654.41899012723881913Q13464Rho-associated protein kinaseRho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) (Rho-associated, coiled-coil-containing protein kinase 1) (Rho-associated, coiled-coil-containing protein kinase I) (ROCK-I) (p160 ROCK-1) (p160ROCK)ROCK1ROCK1actual, predicted, predictedHomo sapiens (Human), Rattus norvegicus (Rat)actual and predicted
C11B211313.015684053.0165363196.3472940080.1666666670.8333333330.52.3260679544.33856135168132P19099Cytochrome P450 11B2Cytochrome P450 11B2, mitochondrial (Aldosterone synthase) (ALDOS) (EC 1.14.15.4) (EC 1.14.15.5) (Aldosterone-synthesizing enzyme) (CYPXIB2) (Cytochrome P-450Aldo) (Cytochrome P-450C18) (Steroid 18-hydroxylase)CYP11B2C11B2actual, predicted, predictedHomo sapiens (Human), Rattus norvegicus (Rat)actual and predicted
CAH12273763.0498730423.0446340496.9133564180.9629629630.6501240690.5972222223.1314387794.937789545452403O43570Carbonic anhydraseCarbonic anhydrase 12 (EC 4.2.1.1) (Carbonate dehydratase XII) (Carbonic anhydrase XII) (CA-XII) (Tumor antigen HOM-RCC-3.1.3)CA12CAH12actual, predictedHomo sapiens (Human)actual and predicted
LPAR30282.9365824522.9365824526.635659198010.52.2024368394.3121941514128Q9UBY5Lysophosphatidic acid receptor Edg-7Lysophosphatidic acid receptor 3 (LPA receptor 3) (LPA-3) (Lysophosphatidic acid receptor Edg-7)LPAR3 EDG7 LPA3LPAR3predictedHomo sapiens (Human), Rattus norvegicus (Rat)predicted
HRH355273.2893909713.2908431597.681019530.0999373430.9407894740.5203634092.7421843084.565553047624532Q9Y5N1Histamine H3 receptorHistamine H3 receptor (H3R) (HH3R) (G-protein coupled receptor 97)HRH3 GPCR97HRH3actual, predicted, predictedCavia porcellus (Guinea pig), Homo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
GHSR01213.8207460463.8207460467.46498299500.9917355370.4958677692.844614014.579367139206121Q92847Ghrelin receptorGrowth hormone secretagogue receptor type 1 (GHS-R) (GH-releasing peptide receptor) (GHRP) (Ghrelin receptor)GHSRGHSRpredictedHomo sapiens (Human), Oryctolagus cuniculus (Rabbit), Rattus norvegicus (Rat)predicted
TBB31311464.1318635344.1318635347.82642857110.5518786950.7750688315.7770131566.366551546282451159Q13509TubulinTubulin beta-3 chain (Tubulin beta-4 chain) (Tubulin beta-III)TUBB3 TUBB4TBB3actual, predictedHomo sapiens (Human)actual and predicted
FURIN03085.6478487325.6478487326.916471933010.54.2358865495.215949577317308P09958FurinFurin (EC 3.4.21.75) (Dibasic-processing enzyme) (Paired basic amino acid residue-cleaving enzyme) (PACE)FURIN FUR PACE PCSK3FURINpredictedHomo sapiens (Human)predicted
TRYB10594.0791936494.0791936497.06921347900.9705882350.4852941182.5978444834.42546750518959Q15661TryptaseTryptase alpha/beta-1 (Tryptase-1) (EC 3.4.21.59) (Tryptase I) (Tryptase alpha-1)TPSAB1 TPS1 TPS2 TPSB1TRYB1predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)predicted
HLA class I histocompatibility antigen A-30984.1273519314.1273519317.158673469010.53.0955139484.709117319898P04439HLA class I histocompatibility antigen A-3HLA class I histocompatibility antigen A-3predictedpredicted
FNTB418794.2704757834.2704757836.6964618050.9978757310.5899152073.2028568374.87066573852621883P49356Protein farnesyl/geranylgeranyl transferaseProtein farnesyltransferase subunit beta (FTase-beta) (EC 2.5.1.58) (CAAX farnesyltransferase subunit beta) (Ras proteins prenyltransferase subunit beta)FNTBFNTBactual, predicted, predictedBos taurus (Bovine), Homo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat), Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)actual and predicted
PDE1B81683.4588171833.4588171836.830257499110.7571022735.4178927236.200287546204176Q01064Phosphodiesterase 1BCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B (Cam-PDE 1B) (EC 3.1.4.17) (63 kDa Cam-PDE)PDE1B PDE1B1 PDES1BPDE1Bactual, predicted, predictedBos taurus (Bovine), Homo sapiens (Human), Rattus norvegicus (Rat)actual and predicted
ADCY90374.1559347094.1559347096.98939281110.8333333337.5501833436.94086712535137O60503Adenylate cyclaseAdenylate cyclase type 9 (EC 4.6.1.1) (ATP pyrophosphate-lyase 9) (Adenylate cyclase type IX) (ACIX) (Adenylyl cyclase 9) (AC9)ADCY9 KIAA0520ADCY9predictedHomo sapiens (Human)predicted
MC4R47533365.0556919295.05569192910.620.98889180410.6787431524.8517003945.64902424771463811P32245Melanocortin receptor (M1 and M4)Melanocortin receptor 4 (MC4-R)MC4RMC4Ractual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
SCN8A974.2703237744.2703237746.4670235110.6750.83756.802943966.74690451616016Q9UQD0Sodium channel alpha subunitSodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6)SCN8A MEDSCN8Aactual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
SL9A12282.9306422762.7942323296.58909269010.52.1979817074.3102140923630P19634Sodium/hydrogen exchanger 1Sodium/hydrogen exchanger 1 (APNH) (Na(+)/H(+) antiporter, amiloride-sensitive) (Na(+)/H(+) exchanger 1) (NHE-1) (Solute carrier family 9 member 1)SLC9A1 APNH1 NHE1SL9A1actual, predicted, predictedHomo sapiens (Human), Oryctolagus cuniculus (Rabbit), Rattus norvegicus (Rat)actual and predicted
GBRG1174353.0577656633.0592880786.3046059780.9690265490.4392284290.7041274894.298831885.7134384818592452Q8N1C3GABA-A receptor; anion channelGamma-aminobutyric acid receptor subunit gamma-1 (GABA(A) receptor subunit gamma-1)GABRG1GBRG1actual, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
JAK14241412.8062667972.8062667977.460.9886046710.546617262.4354132124.5345894654974183P23458JAK1/TYK2Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)JAK1 JAK1A JAK1BJAK1actual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse)actual and predicted
ADCY11374.1568606614.1559347096.9893928110.6666666670.8333333337.5501833436.94086712535137Q08828Adenylate cyclaseAdenylate cyclase type 1 (EC 4.6.1.1) (ATP pyrophosphate-lyase 1) (Adenylate cyclase type I) (Adenylyl cyclase 1) (Ca(2+)/calmodulin-activated adenylyl cyclase)ADCY1ADCY1actual, predicted, predictedBos taurus (Bovine), Homo sapiens (Human)actual and predicted
PCSK60274.7004691264.7004691266.96010.53.5253518444.9001563752827P29122Subtilisin/kexin type 6Proprotein convertase subtilisin/kexin type 6 (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin-like proprotein convertase 4) (SPC4) (Subtilisin/kexin-like protease PACE4)PCSK6 PACE4PCSK6predictedHomo sapiens (Human), Rattus norvegicus (Rat)predicted
CATS21803.4389555923.4229538677.1116858710.0109890110.9120879120.4615384622.4605859544.223241608196182P25774Cathepsin SCathepsin S (EC 3.4.22.27)CTSSCATSactual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse)actual and predicted
ADCY20374.1559347094.1559347096.9893928110.6666666670.8333333337.5501833436.94086712535137Q08462Adenylate cyclaseAdenylate cyclase type 2 (EC 4.6.1.1) (ATP pyrophosphate-lyase 2) (Adenylate cyclase type II) (Adenylyl cyclase 2)ADCY2 KIAA1060ADCY2actual, predicted, predictedHomo sapiens (Human), Rattus norvegicus (Rat)actual and predicted
ADK1503.4811687773.4811687776.5468157450.0098039220.9509803920.4803921572.549382714.3630039716451P55263Adenosine kinaseAdenosine kinase (AK) (EC 2.7.1.20) (Adenosine 5'-phosphotransferase)ADKADKactual, predicted, predictedHomo sapiens (Human), Toxoplasma gondiiactual and predicted
PDE7A2853.2594128993.2594128996.996175775010.52.4445596744.41980439185Q13946Phosphodiesterase 7High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (EC 3.1.4.53) (HCP1) (TM22)PDE7APDE7Aactual, predicted, predictedHomo sapiens (Human)actual and predicted
GBRA3174353.846024793.846024797.119352233110.7041274894.298831885.7134384818592452P34903GABA A receptor alpha-3/beta-2/gamma-2Gamma-aminobutyric acid receptor subunit alpha-3 (GABA(A) receptor subunit alpha-3)GABRA3GBRA3actual, predicted, predictedBos taurus (Bovine), Homo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
NTR121574.8953530734.7963129476.7601852650.510.755.5541637996.18881751312078P30989Neurotensin receptorNeurotensin receptor type 1 (NT-R-1) (NTR1) (High-affinity levocabastine-insensitive neurotensin receptor) (NTRH)NTSR1 NTRRNTR1actual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
EGLN2093.1206262893.1206262897.755760972010.52.3404697174.37354209699Q96KS0Hypoxia-inducible factor prolyl hydroxylase 1Egl nine homolog 2 (EC 1.14.11.29) (Estrogen-induced tag 6) (HPH-3) (Hypoxia-inducible factor prolyl hydroxylase 1) (HIF-PH1) (HIF-prolyl hydroxylase 1) (HPH-1) (Prolyl hydroxylase domain-containing protein 1) (PHD1)EGLN2 EIT6EGLN2predictedHomo sapiens (Human)predicted
CNR145354164.2653328024.2644647497.98538461510.7692307690.7638888896.6386203476.51437019391765869P21554Cannabinoid CB1 receptorCannabinoid receptor 1 (CB-R) (CB1) (CANN6)CNR1 CNRCNR1actual, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
NOS1210704.3370891674.3370891676.8136767050.96296641810.553894593.2528168764.77902972212181072P29475Nitric oxide sythases; iNOS & nNOSNitric oxide synthase, brain (EC 1.14.13.39) (Constitutive NOS) (NC-NOS) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Peptidyl-cysteine S-nitrosylase NOS1) (bNOS)NOS1NOS1actual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
CATK02043.2818474683.2818474687.21228046500.9313725490.4656862752.2814364574.198524319227204P43235Cathepsin KCathepsin K (EC 3.4.22.38) (Cathepsin O) (Cathepsin O2) (Cathepsin X)CTSK CTSO CTSO2CATKpredictedHomo sapiens (Human), Oryctolagus cuniculus (Rabbit)predicted
ACHA341095.8507732775.8507732778.780.13636363610.5454545454.3880799585.297021963148113P32297Neuronal acetylcholine receptor subunit alpha-3Neuronal acetylcholine receptor subunit alpha-3CHRNA3 NACHRA3ACHA3actual, predicted, predictedBos taurus (Bovine), Homo sapiens (Human), Rattus norvegicus (Rat)actual and predicted
ICAM132023.0570629123.0547199966.7056881410.8763779530.9926470590.6578740163.6217777135.362910492456204P05362Intercellular adhesion molecule (ICAM-1), Integrin alpha-L/beta-2Intercellular adhesion molecule 1 (ICAM-1) (Major group rhinovirus receptor) (CD antigen CD54)ICAM1ICAM1actual, predictedHomo sapiens (Human)actual and predicted
CATE1293.7510361053.7524995657.1192121750.0333333330.9666666670.52.9529886364.5836787023530P14091Cathepsin ECathepsin E (EC 3.4.23.34) [Cleaved into: Cathepsin E form I; Cathepsin E form II]CTSECATEactual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse)actual and predicted
MMP25311873.0747002873.0747002877.10841726610.3350806450.6028776983.3129462795.04408474813081240P08253Collagenase72 kDa type IV collagenase (EC 3.4.24.24) (72 kDa gelatinase) (Gelatinase A) (Matrix metalloproteinase-2) (MMP-2) (TBE-1) [Cleaved into: PEX]MMP2 CLG4AMMP2actual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
PARP142202.8752171692.8725402636.6278489690.2924107140.7433035710.5178571432.3799040714.410786675269224P09874Poly [ADP-ribose] polymerase-1Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 1) (ARTD1) (NAD(+) ADP-ribosyltransferase 1) (ADPRT 1) (Poly[ADP-ribose] synthase 1)PARP1 ADPRT PPOLPARP1actual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
MSHR12925.0556919295.05569192910.62010.53.7917689465.018563976510293Q01726Melanocortin receptor (M1 and M4)Melanocyte-stimulating hormone receptor (MSH-R) (Melanocortin receptor 1) (MC1-R)MC1R MSHRMSHRactual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse)actual and predicted
CALRL01584.7505543034.7505543038.3239818610.0727848110.5268987343.6773488954.896088637186158Q16602Adrenomedullin receptor AM1; CALCRL/RAMP2Calcitonin gene-related peptide type 1 receptor (CGRP type 1 receptor) (Calcitonin receptor-like receptor)CALCRL CGRPRCALRLpredictedHomo sapiens (Human), Rattus norvegicus (Rat)predicted
FDFT12502.9303219772.9303468776.57856970110.2636122180.6318061093.3078275875.188814718260251P37268Squalene synthetaseSqualene synthase (SQS) (SS) (EC 2.5.1.21) (FPP:FPP farnesyltransferase) (Farnesyl-diphosphate farnesyltransferase)FDFT1FDFTactual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
LPAR10193.1217432143.1217432146.6115480700.8947368420.4473684212.0753323034.0230372123119Q92633Lysophosphatidic acid receptor Edg-2Lysophosphatidic acid receptor 1 (LPA receptor 1) (LPA-1) (Lysophosphatidic acid receptor Edg-2)LPAR1 EDG2 LPA1LPAR1predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)predicted
CPT1A34932.4409540172.4408400626.88108228210.0443548390.5221774192.0412171884.294834135501496P50416Carnitine O-palmitoyltransferase 1, liver isoformCarnitine O-palmitoyltransferase 1, liver isoform (CPT1-L) (EC 2.3.1.21) (Carnitine O-palmitoyltransferase I, liver isoform) (CPT I) (CPTI-L) (Carnitine palmitoyltransferase 1A)CPT1A CPT1CPT1Aactual, predicted, predictedHomo sapiens (Human), Rattus norvegicus (Rat)actual and predicted
PDE4B3337653.5333146613.5325565927.1104070050.56065960.890.5710461653.4766389974.98474598547313798Q07343Phosphodiesterase 4cAMP-specific 3',5'-cyclic phosphodiesterase 4B (EC 3.1.4.53) (DPDE4) (PDE32)PDE4B DPDE4PDE4Bactual, predictedHomo sapiens (Human), Rattus norvegicus (Rat)actual and predicted
PDE6D123313.8081776563.8081776566.8883333330.05247813410.5087463562.936066224.602725885345343O43924Phosphodiesterase 6Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (GMP-PDE delta) (Protein p17)PDE6D PDEDPDE6Dactual, predicted, predictedBos taurus (Bovine), Homo sapiens (Human)actual and predicted
PDK221252.9552017352.9544746946.45375110.6272965883.3754779385.167044498552127Q15119Pyruvate dehydrogenase kinase[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 2) (PDH kinase 2) (PDKII)PDK2 PDHK2PDK2actual, predicted, predictedHomo sapiens (Human), Rattus norvegicus (Rat)actual and predicted
SC5A2111973.2339962183.2334360437.13036713610.127931130.5639655653.0829695924.83776917414541198P31639Sodium/glucose cotransporter 2Sodium/glucose cotransporter 2 (Na(+)/glucose cotransporter 2) (Low affinity sodium-glucose cotransporter) (Solute carrier family 5 member 2)SLC5A2 SGLT2SC5A2actual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
BMP10382.7199820132.7199820136.848442599010.52.039986514.2399940043838P13497Bone morphogenetic protein 1Bone morphogenetic protein 1 (BMP-1) (EC 3.4.24.19) (Mammalian tolloid protein) (mTld) (Procollagen C-proteinase) (PCP)BMP1 PCOLCBMP1predictedHomo sapiens (Human)predicted
LT4R125223.8958529963.8948334596.46480575710.6068031330.8034015676.5969912726.6546281091486524Q15722Leukotriene B4 receptorLeukotriene B4 receptor 1 (LTB4-R 1) (LTB4-R1) (Chemoattractant receptor-like 1) (G-protein coupled receptor 16) (P2Y purinoceptor 7) (P2Y7)LTB4R BLT BLT1 BLTR CMKRL1 GPR16 P2RY7LT4R1actual, predictedHomo sapiens (Human)actual and predicted
NISCH81632.8531212342.8409058646.81112156210.1476608190.5738304092.8649315824.776576474259171Q9Y2I1NischarinNischarin (Imidazoline receptor 1) (I-1) (IR1) (Imidazoline receptor antisera-selected protein) (hIRAS) (Imidazoline-1 receptor) (I1R) (Imidazoline-1 receptor candidate protein) (I-1 receptor candidate protein) (I1R candidate protein)NISCH IRAS KIAA0975NISCHactual, predictedHomo sapiens (Human), Rattus norvegicus (Rat)actual and predicted
CCR302613.6691760263.6691760266.83230710500.9367816090.4683908052.5884090454.345664039272261P51677C-C chemokine receptor type 3C-C chemokine receptor type 3 (C-C CKR-3) (CC-CKR-3) (CCR-3) (CCR3) (CKR3) (Eosinophil eotaxin receptor) (CD antigen CD193)CCR3 CMKBR3CCR3predictedHomo sapiens (Human), Macaca mulatta (Rhesus macaque), Mus musculus (Mouse), Rattus norvegicus (Rat)predicted
SHBG31733.4381113373.4334016357.1448713010.9807692310.4711538460.7259615385.2411805665.985780702118104P04278Testis-specific androgen-binding proteinSex hormone-binding globulin (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP) (Testosterone-estradiol-binding globulin) (TeBG) (Testosterone-estrogen-binding globulin)SHBGSHBGactual, predicted, predictedHomo sapiens (Human), Oryctolagus cuniculus (Rabbit), Rattus norvegicus (Rat)actual and predicted
SCN9A96893.4907135493.4907135496.70113894710.9949201740.83756.802943966.746904516777689Q15858Sodium channel alpha subunitSodium channel protein type 9 subunit alpha (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1) (PN1) (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7)SCN9A NENASCN9Aactual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
TRPM811973.3394434053.3373291467.1764386670.2508417510.7727272730.5117845122.6145795014.525044547228198Q7Z2W7Transient receptor potential cation channel subfamily M member 8Transient receptor potential cation channel subfamily M member 8 (Long transient receptor potential channel 6) (LTrpC-6) (LTrpC6) (Transient receptor potential p8) (Trp-p8)TRPM8 LTRPC6 TRPP8TRPM8actual, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
PDE1A81683.9737637733.9737637737.25428571410.8571428570.7571022735.4178927236.200287546204176P54750Phosphodiesterase 1ACalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Cam-PDE 1A) (EC 3.1.4.17) (61 kDa Cam-PDE) (hCam-1)PDE1APDE1Aactual, predicted, predictedBos taurus (Bovine), Homo sapiens (Human)actual and predicted
NOS2310894.3370891674.3370891676.8136767050.98580586110.5684142253.2528168764.77902972212961092P35228Nitric oxide synthase, inducibleNitric oxide synthase, inducible (EC 1.14.13.39) (Hepatocyte NOS) (HEP-NOS) (Inducible NO synthase) (Inducible NOS) (iNOS) (NOS type II) (Peptidyl-cysteine S-nitrosylase NOS2)NOS2 NOS2ANOS2actual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
CAH14181273.0514904533.0538824776.5318697780.9629629630.4862068970.5972222223.1314387794.937789545324145Q9ULX7Carbonic anhydraseCarbonic anhydrase 14 (EC 4.2.1.1) (Carbonate dehydratase XIV) (Carbonic anhydrase XIV) (CA-XIV)CA14 UNQ690/PRO1335CAH14actual, predictedHomo sapiens (Human)actual and predicted
PDE9A1272.8186289062.8186289066.849053903010.52.113971684.2728763022828O76083Phosphodiesterase 9AHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (EC 3.1.4.35)PDE9APDE9Aactual, predictedHomo sapiens (Human)actual and predicted
TYK25228342.6312664622.6312664627.460.99237699210.5449641952.3612144074.49171630935762886P29597JAK1/TYK2Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)TYK2TYK2actual, predicted, predictedHomo sapiens (Human)actual and predicted
CAH9234602.9379454372.9394966996.7944694590.9629629630.6832298140.5972222223.1314387794.937789545558483Q16790Carbonic anhydraseCarbonic anhydrase 9 (EC 4.2.1.1) (Carbonate dehydratase IX) (Carbonic anhydrase IX) (CA-IX) (CAIX) (Membrane antigen MN) (P54/58N) (Renal cell carcinoma-associated antigen G250) (RCC-associated antigen G250) (pMW1)CA9 G250 MNCAH9actual, predictedHomo sapiens (Human)actual and predicted
OPRK50848263.9991560773.9991560779.162403438110.7247474755.3535286796.00533268285615334P41145Kappa opioid receptorKappa-type opioid receptor (K-OR-1) (KOR-1)OPRK1 OPRKOPRKactual, predicted, predictedCavia porcellus (Guinea pig), Homo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
OPRX216723.1589350683.1580522346.86858181110.2609516610.6304758313.7845946325.2561505627051674P41146Nociceptin receptorNociceptin receptor (Kappa-type 3 opioid receptor) (KOR-3) (Orphanin FQ receptor)OPRL1 OOR ORL1OPRXactual, predicted, predictedCavia porcellus (Guinea pig), Homo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
CSK213018263.13148813.1229257738110.6583759953.9275655275.4330026724261856P68400Casein kinase IICasein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)CSNK2A1 CK2A1CSK21actual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse)actual and predicted
GRP31553.0725967153.0725967157.19804761910.2523809520.6261904763.6375606145.198802088156Q8IV61RAS guanyl releasing protein 3Ras guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1)RASGRP3 GRP3 KIAA0846GRP3actual, predictedHomo sapiens (Human)actual and predicted
FA10561715.5937176165.5937176166.744490742110.5616836682.6546768264.66578966272536176P00742Coagulation factor XCoagulation factor X (EC 3.4.21.6) (Stuart factor) (Stuart-Prower factor) [Cleaved into: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain]F10FA10actual, predicted, predictedBos taurus (Bovine), Homo sapiens (Human), Oryctolagus cuniculus (Rabbit), Rattus norvegicus (Rat)actual and predicted
ITAV22445.6313850855.6313850857.5133333330.01219512210.53.7316213624.991831716558246P06756Fibronectin receptor (Integrin alpha-5/beta-1 and alpha-V/beta-3)Integrin alpha-V (Vitronectin receptor) (Vitronectin receptor subunit alpha) (CD antigen CD51) [Cleaved into: Integrin alpha-V heavy chain; Integrin alpha-V light chain]ITGAV MSK8 VNRA VTNRITAVactual, predicted, predictedHomo sapiens (Human)actual and predicted
GSK3B4916603.2433973083.2387734686.1381522670.9713024280.5068984550.7391004424.8181995176.00846871318651709P49841Glycogen synthase kinase-3Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)GSK3BGSK3Bactual, actual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
PSN21545934.7192535884.7192535888.1110.5847009233.5394401914.925294736148504608P49810Gamma-secretasePresenilin-2 (PS-2) (EC 3.4.23.-) (AD3LP) (AD5) (E5-1) (STM-2) [Cleaved into: Presenilin-2 NTF subunit; Presenilin-2 CTF subunit]PSEN2 AD4 PS2 PSNL2 STM2PSN2actual, predicted, predictedHomo sapiens (Human)actual and predicted
PE2R326862.8624764432.8624860196.6904717320.9985465120.1923934110.5954699613.0986710934.923958556961688P43115Prostanoid EP3 receptorProstaglandin E2 receptor EP3 subtype (PGE receptor EP3 subtype) (PGE2 receptor EP3 subtype) (PGE2-R) (Prostanoid EP3 receptor)PTGER3PE2R3actual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
NMDZ143483.0009788123.0009788126.915833333110.6884131494.048698485.5895135323360352Q05586Glutamate (NMDA) receptor subunit zeta 1Glutamate receptor ionotropic, NMDA 1 (GluN1) (Glutamate [NMDA] receptor subunit zeta-1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1)GRIN1 NMDAR1NMDZ1actual, predicted, predictedHomo sapiens (Human), Rattus norvegicus (Rat)actual and predicted
ACE20483.4921044113.4921044118.2791666670.62510.5364583333.0850075414.74042369310248Q9BYF1Angiotensin-converting enzymeAngiotensin-converting enzyme 2 (EC 3.4.17.23) (ACE-related carboxypeptidase) (Angiotensin-converting enzyme homolog) (ACEH) (Metalloprotease MPROT15) [Cleaved into: Processed angiotensin-converting enzyme 2]ACE2 UNQ868/PRO1885ACE2predictedHomo sapiens (Human)predicted
GBA20222.6996059652.6996059656.573185888010.52.0247044744.2332019882722Q9HCG7Beta-glucosidaseNon-lysosomal glucosylceramidase (NLGase) (EC 3.2.1.45) (Beta-glucocerebrosidase 2) (Beta-glucosidase 2) (Glucosylceramidase 2)GBA2 KIAA1605 AD035GBA2predictedHomo sapiens (Human), Mus musculus (Mouse)predicted
PDE4D3337653.5333146613.5325565926.8702825970.704119850.890.5710461653.4766389974.98474598547313798Q08499Phosphodiesterase 4cAMP-specific 3',5'-cyclic phosphodiesterase 4D (EC 3.1.4.53) (DPDE3) (PDE43)PDE4D DPDE3PDE4Dactual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
UR2R01713.9301809973.9301809977.43048547300.9795321640.4897660822.8950143614.575167545209171Q9UKP6Urotensin II receptorUrotensin-2 receptor (UR-2-R) (G-protein coupled receptor 14) (Urotensin II receptor) (UR-II-R)UTS2R GPR14UR2RpredictedHomo sapiens (Human), Macaca mulatta (Rhesus macaque), Rattus norvegicus (Rat)predicted
GBRA2174353.4085894043.4085894046.748261856110.7041274894.298831885.7134384818592452P47869GABA A receptor alpha-2/beta-2/gamma-2Gamma-aminobutyric acid receptor subunit alpha-2 (GABA(A) receptor subunit alpha-2)GABRA2GBRA2actual, predicted, predictedBos taurus (Bovine), Homo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
5HT3B92503.6186427313.6186427318.710.50.755.6927206486.2062142441490259O95264Serotonin 3 (5-HT3) receptor5-hydroxytryptamine receptor 3B (5-HT3-B) (5-HT3B) (Serotonin receptor 3B)HTR3B5HT3Bactual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
MK11208203.8671568143.8657040036.2306389610.9903061220.9489299610.5503117913.0543254394.6175217911432840Q15759MAP kinase p38Mitogen-activated protein kinase 11 (MAP kinase 11) (MAPK 11) (EC 2.7.11.24) (Mitogen-activated protein kinase p38 beta) (MAP kinase p38 beta) (p38b) (Stress-activated protein kinase 2b) (SAPK2b) (p38-2)MAPK11 PRKM11 SAPK2 SAPK2BMK11actual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse)actual and predicted
CAH5B19584.7492294714.7492294718.0709090910.9629629630.6363636360.7954545458.3235736826.88610679432477Q9Y2D0Carbonic anhydraseCarbonic anhydrase 5B, mitochondrial (EC 4.2.1.1) (Carbonate dehydratase VB) (Carbonic anhydrase VB) (CA-VB)CA5BCAH5Bactual, predictedHomo sapiens (Human)actual and predicted
PAR103773.6176609973.6176609976.60425087700.9734748010.4867374012.6428585714.450803003398377P25116Proteinase-activated receptor 1Proteinase-activated receptor 1 (PAR-1) (Coagulation factor II receptor) (Thrombin receptor)F2R CF2R PAR1 TRPAR1predictedHomo sapiens (Human), Rattus norvegicus (Rat)predicted
PDE6C123313.5711257253.5711257258.6650.05247813410.5087463562.936066224.582017613345343P51160Phosphodiesterase 6Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' (EC 3.1.4.35) (cGMP phosphodiesterase 6C)PDE6C PDEA2PDE6Cactual, predicted, predictedBos taurus (Bovine), Homo sapiens (Human)actual and predicted
FA713993.7055787553.6940477396.8765435970.02325581410.5006265662.638282814.427814339416399P08709Coagulation factor VIICoagulation factor VII (EC 3.4.21.21) (Proconvertin) (Serum prothrombin conversion accelerator) (SPCA) (Eptacog alfa) [Cleaved into: Factor VII light chain; Factor VII heavy chain]F7FA7actual, predicted, predictedHomo sapiens (Human), Oryctolagus cuniculus (Rabbit)actual and predicted
Insulin-like growth factor binding protein 3082.9087359662.9087359667.61625010.52.1815519754.30291198988P17936Insulin-like growth factor binding protein 3Insulin-like growth factor binding protein 3predictedpredicted
PHKG1164782.9398638872.9398638876.770039216110.5494264512.6307609274.58049657871494Q16816Phosphorylase kinasePhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform (PHK-gamma-M) (EC 2.7.11.19) (Phosphorylase kinase subunit gamma-1) (Serine/threonine-protein kinase PHKG1) (EC 2.7.11.1) (EC 2.7.11.26)PHKG1 PHKGPHKG1actual, predicted, predictedHomo sapiens (Human)actual and predicted
SCNAA9303.4907135493.4907135496.512429086110.83756.802943966.74690451616030Q9Y5Y9Sodium channel alpha subunitSodium channel protein type 10 subunit alpha (Peripheral nerve sodium channel 3) (PN3) (hPN3) (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8)SCN10ASCNAAactual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
CMA12703.1744809713.1367733617.0660678850.2361111110.7708333330.5034722222.6906955184.4146418057872P23946ChymaseChymase (EC 3.4.21.39) (Alpha-chymase) (Mast cell protease I)CMA1 CYH CYMCMA1actual, predictedHomo sapiens (Human)actual and predicted
BRS31463.1418671673.1080522416.1426402760.4787234040.5638297870.5212765962.5932714674.5224663617047P32247Bombesin receptor subtype-3Bombesin receptor subtype-3 (BRS-3)BRS3BRS3actual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
MMP945435623.0747002873.0747002877.10841726610.2057553960.6028776983.3129462795.04408474854384016P14780CollagenaseMatrix metalloproteinase-9 (MMP-9) (EC 3.4.24.35) (92 kDa gelatinase) (92 kDa type IV collagenase) (Gelatinase B) (GELB) [Cleaved into: 67 kDa matrix metalloproteinase-9; 82 kDa matrix metalloproteinase-9]MMP9 CLG4BMMP9actual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse)actual and predicted
PA24B0133.210478663.210478666.746923077010.52.4078589954.4034928871513P0C869Phospholipase A2 group 1VBCytosolic phospholipase A2 beta (cPLA2-beta) (EC 3.1.1.4) (Phospholipase A2 group IVB)PLA2G4BPA24BpredictedHomo sapiens (Human)predicted
CAN20233.3514077483.3514077486.44043478300.9565217390.478260872.3994797924.3055417132323P17655Calpain 2Calpain-2 catalytic subunit (EC 3.4.22.53) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M-type) (Calpain large polypeptide L2) (Calpain-2 large subunit) (Millimolar-calpain) (M-calpain)CAPN2 CANPL2CAN2actual, predicted, predictedHomo sapiens (Human), Sus scrofa (Pig)actual and predicted
ALK3020922.7024365022.7024365026.9469230770.99183160510.5523693582.4947440984.57105294629172122Q9UM73ALK tyrosine kinase receptorALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)ALKALKactual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse)actual and predicted
KCNA322083.8406511233.8405259098.2581862100.9952380950.4976190482.8682857934.597677359474210P22001Voltage-gated potassium channel subunit Kv1.3Potassium voltage-gated channel subfamily A member 3 (HGK5) (HLK3) (HPCN3) (Voltage-gated K(+) channel HuKIII) (Voltage-gated potassium channel subunit Kv1.3)KCNA3 HGK5KCNA3actual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
DCMC0353.3045019243.3045019247.412727291010.52.4783764434.4348339754335O95822Malonyl-CoA decarboxylaseMalonyl-CoA decarboxylase, mitochondrial (MCD) (EC 4.1.1.9)MLYCDDCMCpredictedHomo sapiens (Human), Mus musculus (Mouse)predicted
DNA excision repair protein ERCC-50123.356337083.356337086.402500.9166666670.4583333332.3038168654.1743345821212P28715DNA excision repair protein ERCC-5DNA excision repair protein ERCC-5predictedpredicted
ACHA6065.8507732775.8507732778.78010.54.3880799585.283591092126Q15825Neuronal acetylcholine receptor; alpha3/alpha6/beta2/beta3Neuronal acetylcholine receptor subunit alpha-6CHRNA6ACHA6predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)predicted
CLTR256324.0142930284.0120848366.98586207110.6354937580.8122523736.8224788426.7531134991544637Q9NS75Cysteinyl leukotriene receptorCysteinyl leukotriene receptor 2 (CysLTR2) (G-protein coupled receptor GPCR21) (hGPCR21) (G-protein coupled receptor HG57) (HPN321)CYSLTR2 CYSLT2 CYSLT2R PSEC0146CLTR2actual, predictedHomo sapiens (Human)actual and predicted
AGTR24498633.8926333693.8926333697.50157841210.7152440430.8576220227.2252541327.01502460122661312P50052Angiotensin II receptorType-2 angiotensin II receptor (Angiotensin II type-2 receptor) (AT2)AGTR2AGTR2actual, predicted, predictedHomo sapiens (Human), Rattus norvegicus (Rat)actual and predicted
S1PR1211643.4301930133.4003444767.1219705160.0342342340.9729729730.5036036042.6341518254.500755028202185P21453Sphingosine 1-phosphate receptor Edg-1Sphingosine 1-phosphate receptor 1 (S1P receptor 1) (S1P1) (Endothelial differentiation G-protein coupled receptor 1) (Sphingosine 1-phosphate receptor Edg-1) (S1P receptor Edg-1) (CD antigen CD363)S1PR1 CHEDG1 EDG1S1PR1actual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
MOT10552.7445939172.7445939178.08944478710.0951515150.5475757582.413738294.565369699755P53985Monocarboxylate transporter 1Monocarboxylate transporter 1 (MCT 1) (Solute carrier family 16 member 1)SLC16A1 MCT1MOT1actual, predicted, predictedHomo sapiens (Human), Rattus norvegicus (Rat)actual and predicted
MMP122693.5471699333.5471699336.3739356060.0140845070.9295774650.4718309862.555484324.3279298848171P39900Matrix metalloproteinase 12Macrophage metalloelastase (MME) (EC 3.4.24.65) (Macrophage elastase) (ME) (hME) (Matrix metalloproteinase-12) (MMP-12)MMP12 HMEMMP12actual, predicted, predictedHomo sapiens (Human), Oryctolagus cuniculus (Rabbit), Rattus norvegicus (Rat)actual and predicted
PDE8B0173.2613992313.2613992317.37010.52.4460494234.420466411717O95263Phosphodiesterase 8High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B (HsPDE8B) (EC 3.1.4.53) (Cell proliferation-inducing gene 22 protein)PDE8B PIG22PDE8BpredictedHomo sapiens (Human)predicted
PDE1033423.182152723.17226117.8935662880.0057971010.8768115940.4413043482.1116209154.002746559356345Q9Y233Phosphodiesterase 10AcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (EC 3.1.4.17) (EC 3.1.4.35)PDE10APDE10actual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
FFAR13722.6834919972.6734260326.6475956950.3766666670.720.5483333332.520160084.55005288810875O14842Free fatty acid receptor 1Free fatty acid receptor 1 (G-protein coupled receptor 40)FFAR1 GPR40FFAR1actual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
PP1G0134.4289005424.4289005427.641962601010.53.3216754064.8096335143213P36873Serine/threonine protein phosphatase PP1-gamma catalytic subunitSerine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)PPP1CCPP1GpredictedHomo sapiens (Human)predicted
CXCR30943.2226054063.2226054066.6836721500.9787234040.4893617022.3600052144.33661314911094P49682C-X-C chemokine receptor type 3C-X-C chemokine receptor type 3 (CXC-R3) (CXCR-3) (CKR-L2) (G protein-coupled receptor 9) (Interferon-inducible protein 10 receptor) (IP-10 receptor) (CD antigen CD183)CXCR3 GPR9CXCR3predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)predicted
MTR1B18012.9842050472.9830904957.7179970020.9979218620.2041516840.5953743053.1299407594.9638970511104802P49286Melatonin receptorMelatonin receptor type 1B (Mel-1B-R) (Mel1b receptor)MTNR1BMTR1Bactual, predictedGallus gallus (Chicken), Homo sapiens (Human)actual and predicted
PDE4C3337653.5333146613.5325565926.7070940170.6410256410.890.5710461653.4766389974.98474598547313798Q08493Phosphodiesterase 4cAMP-specific 3',5'-cyclic phosphodiesterase 4C (EC 3.1.4.53) (DPDE1) (PDE21)PDE4C DPDE1PDE4Cactual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
NU4M254.5507865394.5471039086.68454982111110.239269718.18359551377P03905NADH-ubiquinone oxidoreductase chain 4NADH-ubiquinone oxidoreductase chain 4 (EC 1.6.5.3) (NADH dehydrogenase subunit 4)MT-ND4 MTND4 NADH4 ND4NU4Mactual, predictedHomo sapiens (Human)actual and predicted
VIPR20395.3772683385.3772683388.995128205010.54.0329512545.1257561134339P41587Vasoactive intestinal polypeptide receptor 2Vasoactive intestinal polypeptide receptor 2 (VIP-R-2) (Helodermin-preferring VIP receptor) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) (PACAP-R3) (VPAC2)VIPR2 VIP2RVIPR2predictedHomo sapiens (Human)predicted
Apolipoprotein B-1000153.7095578073.7095578078.274666667010.52.7821683564.5698526021515P04114Apolipoprotein B-100Apolipoprotein B-100predictedpredicted
AL5AP04393.3099557713.3099557717.62522507010.52.4661175834.429385592504439P202925-lipoxygenase activating proteinArachidonate 5-lipoxygenase-activating protein (FLAP) (MK-886-binding protein)ALOX5AP FLAPAL5APpredictedHomo sapiens (Human), Rattus norvegicus (Rat)predicted
TSPO0103.1138810513.1138810517.424558303010.52.3354107884.3712936841010P30536Translocator proteinTranslocator protein (Mitochondrial benzodiazepine receptor) (PKBS) (Peripheral-type benzodiazepine receptor) (PBR)TSPO BZRP MBRTSPOactual, predicted, predictedHomo sapiens (Human), Rattus norvegicus (Rat)actual and predicted
MMP861443.2595573923.2490705147.10841726610.9266666670.6028776983.3129462795.044084748710150P22894CollagenaseNeutrophil collagenase (EC 3.4.24.34) (Matrix metalloproteinase-8) (MMP-8) (PMNL collagenase) (PMNL-CL)MMP8 CLG1MMP8actual, predicted, predictedHomo sapiens (Human)actual and predicted
MMP1362053.0969944923.0747002877.2382196310.9146919430.6028776983.3129462795.044084748710211P45452CollagenaseCollagenase 3 (EC 3.4.24.-) (Matrix metalloproteinase-13) (MMP-13)MMP13MMP13actual, predicted, predictedBos taurus (Bovine), Homo sapiens (Human), Mus musculus (Mouse)actual and predicted
GSTM2092.7025880822.7025880827.185020242010.52.0269410614.23419602799P28161Glutathione S-transferase Mu 2Glutathione S-transferase Mu 2 (EC 2.5.1.18) (GST class-mu 2) (GSTM2-2)GSTM2 GST4GSTM2predictedHomo sapiens (Human)predicted
BACE11110574.2489892284.2489892287.03280.1389111820.840.4729356162.8086279944.40884997514301068P56817Beta-secretase (BACE)Beta-secretase 1 (EC 3.4.23.46) (Aspartyl protease 2) (ASP2) (Asp 2) (Beta-site amyloid precursor protein cleaving enzyme 1) (Beta-site APP cleaving enzyme 1) (Memapsin-2) (Membrane-associated aspartic protease 2)BACE1 BACE KIAA1149BACE1actual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse)actual and predicted
CCR841972.5668308962.5651828866.73589870110.1044776120.5522388062.4488797194.537202339241201P51685C-C chemokine receptor type 8C-C chemokine receptor type 8 (C-C CKR-8) (CC-CKR-8) (CCR-8) (CC chemokine receptor CHEMR1) (CMKBRL2) (Chemokine receptor-like 1) (CKR-L1) (GPR-CY6) (GPRCY6) (TER1) (CD antigen CDw198)CCR8 CKRL1 CMKBR8 CMKBRL2CCR8actual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse)actual and predicted
TRPV1773643.4143659843.3210249396.3575262570.1335600910.91383220.5236961452.9157653434.629429629605441Q8NER1Vanilloid receptorTransient receptor potential cation channel subfamily V member 1 (TrpV1) (Capsaicin receptor) (Osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1)TRPV1 VR1TRPV1actual, predicted, predictedCavia porcellus (Guinea pig), Homo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
HDA105287003.4835569833.4835192746.3155710430.9974160210.4295990850.7127779884.9004524285.913038917369348752Q969S8Histone deacetylaseHistone deacetylase 10 (HD10) (EC 3.5.1.98)HDAC10HDA10actual, predictedHomo sapiens (Human)actual and predicted
PLCB0132.7113350752.7113350756.814140002010.52.0335013064.2371116921313O151201-acylglycerol-3-phosphate O-acyltransferase beta1-acyl-sn-glycerol-3-phosphate acyltransferase beta (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 2) (1-AGP acyltransferase 2) (1-AGPAT 2) (Lysophosphatidic acid acyltransferase beta) (LPAAT-beta)AGPAT2PLCBpredictedHomo sapiens (Human)predicted
CAH5A22784.7492294714.7492294718.0709090910.9629629630.6363636360.7954545458.3235736826.886106794324100P35218Carbonic anhydraseCarbonic anhydrase 5A, mitochondrial (EC 4.2.1.1) (Carbonate dehydratase VA) (Carbonic anhydrase VA) (CA-VA)CA5A CA5CAH5Aactual, predictedHomo sapiens (Human)actual and predicted
P2RX312953.1301818993.1301818997.0161266890.0304054050.9679054050.4991554052.3477001144.371096669298296P56373P2X purinoceptor 3P2X purinoceptor 3 (P2X3) (ATP receptor) (Purinergic receptor)P2RX3P2RX3actual, predicted, predictedHomo sapiens (Human), Rattus norvegicus (Rat)actual and predicted
BCL2513162.7094040542.7094343297.4666906490.9984859950.3694171080.6839515523.6418667445.46281169716291321P10415Apoptosis regulator Bcl-2Apoptosis regulator Bcl-2BCL2BCL2actual, predictedHomo sapiens (Human)actual and predicted
NPY4R0654.9240009484.9240009486.63643686800.9846153850.4923076923.652635354.92338493111865P50391Neuropeptide Y receptor type 4Neuropeptide Y receptor type 4 (NPY4-R) (Pancreatic polypeptide receptor 1) (PP1)NPY4R PPYR1NPY4RpredictedHomo sapiens (Human)predicted
CP1B1151432.958818892.9336512336.48075112810.3251054850.6625527433.8772707255.403291247193158Q16678Cytochrome P450 1B1Cytochrome P450 1B1 (EC 1.14.14.1) (CYPIB1)CYP1B1CP1B1actual, predictedHomo sapiens (Human)actual and predicted
GALR10455.3159877115.3159877117.893381834010.53.9869907835.1053292376145P47211Galanin receptor 1Galanin receptor type 1 (GAL1-R) (GALR-1)GALR1 GALNR GALNR1GALR1predictedHomo sapiens (Human), Rattus norvegicus (Rat)predicted
GRPR0344.7310984834.7310984837.122337545010.53.5483238624.9103661614834P30550Gastrin releasing peptide receptorGastrin-releasing peptide receptor (GRP-R) (GRP-preferring bombesin receptor)GRPRGRPRpredictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)predicted
SCN3A611264.4208311864.4208311866.654333757110.83756.802943966.7469045161017187Q9NY46Sodium channel alpha subunitSodium channel protein type 3 subunit alpha (Sodium channel protein brain III subunit alpha) (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subtype III) (Voltage-gated sodium channel subunit alpha Nav1.3)SCN3A KIAA1356 NAC3SCN3Aactual, predicted, predictedHomo sapiens (Human), Rattus norvegicus (Rat)actual and predicted
MMP145342653.0747002873.0747002877.10841726610.2057553960.6028776983.3129462795.04408474861324718P03956CollagenaseInterstitial collagenase (EC 3.4.24.7) (Fibroblast collagenase) (Matrix metalloproteinase-1) (MMP-1) [Cleaved into: 22 kDa interstitial collagenase; 27 kDa interstitial collagenase]MMP1 CLGMMP1actual, predicted, predictedHomo sapiens (Human)actual and predicted
MDM2195853.4748591393.4485825657.21009195300.9814814810.4907407412.5448189744.411597638794604Q00987Tumour suppressor p53/oncoprotein Mdm2E3 ubiquitin-protein ligase Mdm2 (EC 2.3.2.27) (Double minute 2 protein) (Hdm2) (Oncoprotein Mdm2) (RING-type E3 ubiquitin transferase Mdm2) (p53-binding protein Mdm2)MDM2MDM2actual, predicted, predictedCanis lupus familiaris (Dog) (Canis familiaris), Homo sapiens (Human)actual and predicted
LIPE0913.7735022883.7735022886.9638744900.9890109890.4945054952.8008776384.55453739311791Q9Y5X9Endothelial lipaseEndothelial lipase (EC 3.1.1.3) (Endothelial cell-derived lipase) (EDL) (EL)LIPG UNQ387/PRO719LIPEpredictedHomo sapiens (Human), Mus musculus (Mouse)predicted
MCHR145864.1277919654.1277919657.2440163910.03225806510.5161290323.271853634.81679087645590Q99705Melanin-concentrating hormone receptorMelanin-concentrating hormone receptor 1 (MCH receptor 1) (MCH-R1) (MCHR-1) (G-protein coupled receptor 24) (MCH-1R) (MCH1R) (MCHR) (SLC-1) (Somatostatin receptor-like protein)MCHR1 GPR24 SLC1MCHR1actual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
OX1R292414.2653328024.2644647496.77027662210.9388888890.7638888896.6386203476.514370193318270O43613Cannabinoid CB1 receptor/orexin receptor 1 complexOrexin receptor type 1 (Ox-1-R) (Ox1-R) (Ox1R) (Hypocretin receptor type 1)HCRTR1OX1Ractual, predicted, predictedHomo sapiens (Human), Rattus norvegicus (Rat)actual and predicted
CP26A0192.9218502252.9218502256.943684211010.52.1913876694.3072834082019O43174Cytochrome P450 26A1Cytochrome P450 26A1 (EC 1.14.13.-) (Cytochrome P450 retinoic acid-inactivating 1) (Cytochrome P450RAI) (hP450RAI) (Retinoic acid 4-hydroxylase) (Retinoic acid-metabolizing cytochrome)CYP26A1 CYP26 P450RAI1CP26ApredictedHomo sapiens (Human)predicted
BRAF2224282.8483384932.8479373786.6658136650.9995918370.1863707480.5929812933.0318881034.90265478139992450P15056Serine/threonine-protein kinase B-rafSerine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (p94) (v-Raf murine sarcoma viral oncogene homolog B1)BRAF BRAF1 RAFB1BRAFactual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse)actual and predicted
KCNA10604.1501971564.1501971569.514906765010.53.1126478674.7167323856960Q09470Voltage-gated potassium channel subunit Kv1.1Potassium voltage-gated channel subfamily A member 1 (Voltage-gated K(+) channel HuKI) (Voltage-gated potassium channel HBK1) (Voltage-gated potassium channel subunit Kv1.1)KCNA1KCNA1predictedHomo sapiens (Human), Rattus norvegicus (Rat)predicted
GP1190212.5161416352.5161416356.940372195010.51.8871062264.1720472123021Q8TDV5Glucose-dependent insulinotropic receptorGlucose-dependent insulinotropic receptor (G-protein coupled receptor 119)GPR119GP119predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)predicted
BIRC301054.6581510994.6581510997.08210372500.990476190.4952380953.4697147694.854304335154105Q13489Baculoviral IAP repeat-containing protein 3Baculoviral IAP repeat-containing protein 3 (EC 2.3.2.27) (Apoptosis inhibitor 2) (API2) (Cellular inhibitor of apoptosis 2) (C-IAP2) (IAP homolog C) (Inhibitor of apoptosis protein 1) (hIAP-1) (hIAP1) (RING finger protein 49) (RING-type E3 ubiquitin transferase BIRC3) (TNFR2-TRAF-signaling complex protein 1)BIRC3 API2 MIHC RNF49BIRC3predictedHomo sapiens (Human)predicted
ERG70693.5337933333.5337933336.332282411010.52.6503454.51126444410169P48449Lanosterol synthaseLanosterol synthase (EC 5.4.99.7) (2,3-epoxysqualene--lanosterol cyclase) (Oxidosqualene--lanosterol cyclase) (OSC) (hOSC)LSS OSCERG7predictedHomo sapiens (Human), Pneumocystis carinii, Rattus norvegicus (Rat), Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)predicted
PACR0464.8710592334.8710592336.83485640400.5471014490.2735507252.4074277223.44735790910946P41586Pituitary adenylate cyclase-activating polypeptide type I receptorPituitary adenylate cyclase-activating polypeptide type I receptor (PACAP type I receptor) (PACAP-R-1) (PACAP-R1)ADCYAP1R1PACRpredictedHomo sapiens (Human), Rattus norvegicus (Rat)predicted
KISSR12543.7792724183.7775113957.94684355910.5696078430.7848039226.9660947156.491783616406255Q969F8Metastin receptorKiSS-1 receptor (KiSS-1R) (G-protein coupled receptor 54) (G-protein coupled receptor OT7T175) (hOT7T175) (Hypogonadotropin-1) (Kisspeptins receptor) (Metastin receptor)KISS1R AXOR12 GPR54KISSRactual, predicted, predictedHomo sapiens (Human), Rattus norvegicus (Rat)actual and predicted
ACOD0402.940063292.940063297.25312500.950.4752.0762042744.1466877634440O00767Acyl-CoA desaturaseAcyl-CoA desaturase (EC 1.14.19.1) (Delta(9)-desaturase) (Delta-9 desaturase) (Fatty acid desaturase) (Stearoyl-CoA desaturase) (hSCD1)SCDACODpredictedHomo sapiens (Human)predicted
CAC1I11033.0136622783.0136622786.6074425510.3605769230.6802884623.9830376215.539810503133104Q9P0X4Voltage-gated T-type calcium channel alpha-1I subunitVoltage-dependent T-type calcium channel subunit alpha-1I (Voltage-gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3)CACNA1I KIAA1120CAC1Iactual, predictedHomo sapiens (Human)actual and predicted
BIRC201934.5560733374.5560733377.548830948010.53.3770959454.800210974276193Q13490Baculoviral IAP repeat-containing protein 2Baculoviral IAP repeat-containing protein 2 (EC 2.3.2.27) (Cellular inhibitor of apoptosis 1) (C-IAP1) (IAP homolog B) (Inhibitor of apoptosis protein 2) (hIAP-2) (hIAP2) (RING finger protein 48) (RING-type E3 ubiquitin transferase BIRC2) (TNFR2-TRAF-signaling complex protein 2)BIRC2 API1 MIHB RNF48BIRC2predictedHomo sapiens (Human)predicted
M3K7222162.9727250082.9727250086.6121428570.96323529410.5828081233.2142305254.87121934269238O43318Mitogen-activated protein kinase kinase kinase 7Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1)MAP3K7 TAK1M3K7actual, predicted, predictedHomo sapiens (Human)actual and predicted
LIPS0223.0062098563.0062098566.77784548010.52.2546573924.3354032852322Q05469Hormone sensitive lipaseHormone-sensitive lipase (HSL) (EC 3.1.1.79)LIPELIPSactual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
WDR50154.5305282514.5305282516.30222222200.8444444440.4222222222.9770407894.3249908992815P61964WD repeat-containing protein 5WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein)WDR5 BIG3WDR5predictedHomo sapiens (Human)predicted
PSB861684.1473160554.1470173366.77770903810.4306476570.7153238286.967348916.1512642082109174P2806226S proteosomeProteasome subunit beta type-8 (EC 3.4.25.1) (Low molecular mass protein 7) (Macropain subunit C13) (Multicatalytic endopeptidase complex subunit C13) (Proteasome component C13) (Proteasome subunit beta-5i) (Really interesting new gene 10 protein)PSMB8 LMP7 PSMB5i RING10 Y2PSB8actual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse)actual and predicted
LPAR5083.4973605613.4973605618.144048988010.52.6230204214.499120187158Q9H1C0Lysophosphatidic acid receptor 5Lysophosphatidic acid receptor 5 (LPA receptor 5) (LPA-5) (G-protein coupled receptor 92) (G-protein coupled receptor 93)LPAR5 GPR92 GPR93LPAR5predictedHomo sapiens (Human)predicted
APJ0504.3601530944.3601530947.647017044010.53.2701148214.78671769812750P35414Apelin receptorApelin receptor (Angiotensin receptor-like 1) (G-protein coupled receptor APJ) (G-protein coupled receptor HG11)APLNR AGTRL1 APJAPJpredictedHomo sapiens (Human)predicted
GBRA6174354.9788523594.9694796637.0225110.7041274894.9615764625.7134384818592452Q16445GABA A receptor alpha-6/beta-2/gamma-2Gamma-aminobutyric acid receptor subunit alpha-6 (GABA(A) receptor subunit alpha-6)GABRA6GBRA6actual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
QRFPR0174.2928117384.2928117386.969411765010.53.2196088034.7642705792017Q96P65Pyroglutamylated RFamide peptide receptorPyroglutamylated RFamide peptide receptor (AQ27) (G-protein coupled receptor 103) (Orexigenic neuropeptide QRFP receptor) (SP9155)QRFPR GPR103QRFPRpredictedHomo sapiens (Human)predicted
LPAR4093.0590657673.0590657677.811111111010.52.2942993254.353021922159Q99677Lysophosphatidic acid receptor 4Lysophosphatidic acid receptor 4 (LPA receptor 4) (LPA-4) (G-protein coupled receptor 23) (P2Y purinoceptor 9) (P2Y9) (P2Y5-like receptor) (Purinergic receptor 9)LPAR4 GPR23 LPA4 P2RY9LPAR4predictedHomo sapiens (Human), Mus musculus (Mouse)predicted
DGAT10923.0295428683.0295428687.0221906800.9891304350.4945652172.2427274944.30694907210292O75907Diacylglycerol O-acyltransferase 1Diacylglycerol O-acyltransferase 1 (EC 2.3.1.20) (ACAT-related gene product 1) (Acyl-CoA retinol O-fatty-acyltransferase) (ARAT) (Retinol O-fatty-acyltransferase) (EC 2.3.1.76) (Diglyceride acyltransferase)DGAT1 AGRP1 DGATDGAT1predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)predicted
E2AK35243.541126243.3901995167.243833731010.52.655844684.5137087474329Q9NZJ5Eukaryotic translation initiation factor 2-alpha kinase 3Eukaryotic translation initiation factor 2-alpha kinase 3 (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase) (HsPEK)EIF2AK3 PEK PERKE2AK3actual, predictedHomo sapiens (Human)actual and predicted
S22AC13572.9224367752.9224367756.324741410.9995344510.2555865920.6275605213.3859423055.157882401392358Q96S37Solute carrier family 22 member 12Solute carrier family 22 member 12 (Organic anion transporter 4-like protein) (Renal-specific transporter) (RST) (Urate anion exchanger 1)SLC22A12 OATL4 URAT1 UNQ6453/PRO34004S22ACactual, predictedHomo sapiens (Human)actual and predicted
TNKS25394.2049205824.2049205826.880.36363636410.6079545453.813231245.1221868596044Q9H2K2Tankyrase 1/2Tankyrase-2 (TANK2) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 6) (ARTD6) (Poly [ADP-ribose] polymerase 5B) (TNKS-2) (TRF1-interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase II) (Tankyrase-like protein) (Tankyrase-related protein)TNKS2 PARP5B TANK2 TNKLTNKS2actual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse)actual and predicted
TNKS14334.2049205824.2049205826.880.20270270310.5472972973.1536904364.7349735275237O95271Tankyrase 1/2Tankyrase-1 (TANK1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 5) (ARTD5) (Poly [ADP-ribose] polymerase 5A) (TNKS-1) (TRF1-interacting ankyrin-related ADP-ribose polymerase) (Tankyrase I)TNKS PARP5A PARPL TIN1 TINF1 TNKS1TNKS1actual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse)actual and predicted
NAMPT0323.0314422693.0314422697.184284088010.52.2735817024.343814093732P43490Nicotinamide phosphoribosyltransferaseNicotinamide phosphoribosyltransferase (NAmPRTase) (Nampt) (EC 2.4.2.12) (Pre-B-cell colony-enhancing factor 1) (Pre-B cell-enhancing factor) (Visfatin)NAMPT PBEF PBEF1NAMPTpredictedHomo sapiens (Human)predicted
CDK9199692.9478603282.9393139047.89110.5556680162.5893579844.6062147011103988P50750CDK9/Cyclin KCyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division cycle 2-like protein kinase 4) (Cell division protein kinase 9) (Serine/threonine-protein kinase PITALRE) (Tat-associated kinase complex catalytic subunit)CDK9 CDC2L4 TAKCDK9actual, predicted, predictedHomo sapiens (Human)actual and predicted
PK3CD2020022.9779415752.9779415756.6146362470.99455984210.5415871842.3647903394.4898536425482022O00329PI3-kinase class IPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (PI3-kinase subunit delta) (PI3K-delta) (PI3Kdelta) (PtdIns-3-kinase subunit delta) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta) (PtdIns-3-kinase subunit p110-delta) (p110delta)PIK3CDPK3CDactual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse)actual and predicted
ST1A1214.6258300564.6258300566.26688017210.6666666670.8333333338.4708860887.097498907133P50225Sulfotransferase 1A1Sulfotransferase 1A1 (ST1A1) (EC 2.8.2.1) (Aryl sulfotransferase 1) (HAST1/HAST2) (Phenol sulfotransferase 1) (Phenol-sulfating phenol sulfotransferase 1) (P-PST 1) (ST1A3) (Thermostable phenol sulfotransferase) (Ts-PST)SULT1A1 STP STP1 OK/SW-cl.88ST1A1actual, predictedHomo sapiens (Human)actual and predicted
ENTK24463.9403740083.9148918637.31371443700.9857142860.4928571432.9185096954.5991722887170P98073EnteropeptidaseEnteropeptidase (EC 3.4.21.9) (Enterokinase) (Serine protease 7) (Transmembrane protease serine 15) [Cleaved into: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain]TMPRSS15 ENTK PRSS7ENTKactual, predictedHomo sapiens (Human)actual and predicted
SCRB10113.3368748943.3368748948.327272727010.52.502656174.4456249651111Q8WTV0Scavenger receptor class B member 1Scavenger receptor class B member 1 (SRB1) (CD36 and LIMPII analogous 1) (CLA-1) (CD36 antigen-like 1) (Collagen type I receptor, thrombospondin receptor-like 1) (SR-BI) (CD antigen CD36)SCARB1 CD36L1 CLA1SCRB1actual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse)actual and predicted
KCNJ10243.1178969673.1178969676.754375010.52.3384227264.3726323222624P48048ATP-sensitive inward rectifier potassium channel 1ATP-sensitive inward rectifier potassium channel 1 (ATP-regulated potassium channel ROM-K) (Inward rectifier K(+) channel Kir1.1) (Potassium channel, inwardly rectifying subfamily J member 1)KCNJ1 ROMK1KCNJ1predictedHomo sapiens (Human), Rattus norvegicus (Rat)predicted
OX2R292853.7680377273.7333528126.87933660600.9649681530.4824840762.7356496424.472573085368314O43614Orexin receptor 2Orexin receptor type 2 (Ox-2-R) (Ox2-R) (Ox2R) (Hypocretin receptor type 2)HCRTR2OX2Ractual, predicted, predictedCanis lupus familiaris (Dog) (Canis familiaris), Homo sapiens (Human), Rattus norvegicus (Rat)actual and predicted
ACHB242565.0505799475.0505799478.780.13636363610.5454545454.3842175225.297021963319260P17787Neuronal acetylcholine receptor; alpha2/beta2Neuronal acetylcholine receptor subunit beta-2CHRNB2ACHB2actual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
ACHB441095.8507732775.8507732777.520.05309734510.5154867264.3880799585.283591092148113P30926Neuronal acetylcholine receptor; alpha3/beta4Neuronal acetylcholine receptor subunit beta-4CHRNB4ACHB4actual, predicted, predictedBos taurus (Bovine), Homo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
HDAC25287003.6016063563.6016063566.91579671210.5606936420.7803468215.7992955646.402847591369348752Q92769Histone deacetylaseHistone deacetylase 2 (HD2) (EC 3.5.1.98)HDAC2HDAC2actual, predictedHomo sapiens (Human)actual and predicted
ITB322824.1718196554.1718196557.9620.24468085110.5041371162.8738772614.610612116626282P05106Fibronectin receptor (Integrin alpha-5/beta-1 and alpha-V/beta-3)Integrin beta-3 (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD antigen CD61)ITGB3 GP3AITB3actual, predicted, predictedHomo sapiens (Human)actual and predicted
S27A10162.5575404122.5575404126.298125010.51.9181553094.1858468041716Q6PCB7Long-chain fatty acid transport protein 1Long-chain fatty acid transport protein 1 (FATP-1) (Fatty acid transport protein 1) (EC 6.2.1.-) (Solute carrier family 27 member 1)SLC27A1 ACSVL5 FATP1S27A1predictedHomo sapiens (Human), Mus musculus (Mouse)predicted
LT4R213433.8958529963.8948334596.46480575710.6068031330.8034015676.5969912726.6546281091486344Q9NPC1Leukotriene B4 receptorLeukotriene B4 receptor 2 (LTB4-R 2) (LTB4-R2) (LTB4 receptor JULF2) (Leukotriene B4 receptor BLT2) (Seven transmembrane receptor BLTR2)LTB4R2 BLT2R BLTR2LT4R2actual, predictedHomo sapiens (Human)actual and predicted
FNTA418794.2704757834.2704757836.696461805110.5899152073.2028568374.87066573852621883P49354Geranylgeranyl transferase type IProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (EC 2.5.1.58) (EC 2.5.1.59) (CAAX farnesyltransferase subunit alpha) (FTase-alpha) (Ras proteins prenyltransferase subunit alpha) (Type I protein geranyl-geranyltransferase subunit alpha) (GGTase-I-alpha)FNTAFNTAactual, predicted, predictedBos taurus (Bovine), Homo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat), Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)actual and predicted
GBRB2174353.846024793.846024797.119352233110.7041274894.9615764625.7134384818592452P47870GABA A receptor alpha-2/beta-2/gamma-2Gamma-aminobutyric acid receptor subunit beta-2 (GABA(A) receptor subunit beta-2)GABRB2GBRB2actual, predicted, predictedHomo sapiens (Human), Rattus norvegicus (Rat)actual and predicted
GBRG2174354.9788523594.9694796637.11935223310.7471264370.7420634925.3404596216.0754218598592452P18507GABA A receptor alpha-1/beta-1/gamma-2Gamma-aminobutyric acid receptor subunit gamma-2 (GABA(A) receptor subunit gamma-2)GABRG2GBRG2actual, predicted, predictedBos taurus (Bovine), Homo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
ADCY60374.1559347094.1559347096.9893928110.6666666670.8333333337.5501833436.94086712535137O43306Adenylate cyclaseAdenylate cyclase type 6 (EC 4.6.1.1) (ATP pyrophosphate-lyase 6) (Adenylate cyclase type VI) (Adenylyl cyclase 6) (Ca(2+)-inhibitable adenylyl cyclase)ADCY6 KIAA0422ADCY6actual, predicted, predictedHomo sapiens (Human), Rattus norvegicus (Rat)actual and predicted
ADCY30374.1559347094.1559347096.9893928110.6666666670.8333333337.5501833436.94086712535137O60266Adenylate cyclaseAdenylate cyclase type 3 (EC 4.6.1.1) (ATP pyrophosphate-lyase 3) (Adenylate cyclase type III) (AC-III) (Adenylate cyclase, olfactive type) (Adenylyl cyclase 3) (AC3)ADCY3 KIAA0511ADCY3actual, predicted, predictedHomo sapiens (Human), Rattus norvegicus (Rat)actual and predicted
ADCY40374.1559347094.1559347096.9893928110.6666666670.8333333337.5501833436.94086712535137Q8NFM4Adenylate cyclaseAdenylate cyclase type 4 (EC 4.6.1.1) (ATP pyrophosphate-lyase 4) (Adenylate cyclase type IV) (Adenylyl cyclase 4)ADCY4ADCY4actual, predicted, predictedHomo sapiens (Human), Rattus norvegicus (Rat)actual and predicted
ADCY80374.1559347094.1559347096.9893928110.6666666670.8333333337.5501833436.94086712535137P40145Adenylate cyclaseAdenylate cyclase type 8 (EC 4.6.1.1) (ATP pyrophosphate-lyase 8) (Adenylate cyclase type VIII) (Adenylyl cyclase 8) (AC8) (Ca(2+)/calmodulin-activated adenylyl cyclase)ADCY8ADCY8actual, predicted, predictedHomo sapiens (Human), Rattus norvegicus (Rat)actual and predicted
ITB701263.1240503213.1240503217.0305994680.0555555560.9682539680.5119047622.4739179584.45404852256126P26010Integrin alpha-4/beta-7Integrin beta-7 (Gut homing receptor beta subunit)ITGB7ITB7predictedHomo sapiens (Human), Mus musculus (Mouse)predicted
CSK2B265603.13148813.12292577380.89178043210.6583759953.9275655275.433002671099586P67870Casein kinase IICasein kinase II subunit beta (CK II beta) (Phosvitin) (Protein G5a)CSNK2B CK2N G5ACSK2Bactual, predicted, predictedHomo sapiens (Human)actual and predicted
CCND310473.1367320833.1370828716.6128083940.15789473710.5263157892.4146397394.5117697098857P30281CDK4/Cyclin D3G1/S-specific cyclin-D3CCND3CCND3actual, predicted, predictedHomo sapiens (Human)actual and predicted
CCND1419594.0149550844.0149550846.6128083940.99949057610.5904440483.1297092864.92917964122091963P24385CDK6/cyclin D1G1/S-specific cyclin-D1 (B-cell lymphoma 1 protein) (BCL-1) (BCL-1 oncogene) (PRAD1 oncogene)CCND1 BCL1 PRAD1CCND1actual, predicted, predictedHomo sapiens (Human)actual and predicted
CCND20384.2137663654.2137663656.6128083940.15789473710.5263157893.1603247744.7379221227938P30279CDK6/cyclin D2G1/S-specific cyclin-D2CCND2CCND2predictedHomo sapiens (Human)predicted
GBRB1174353.3849957373.3538919286.30460597810.4841269840.7420634925.3404596216.0754218598592452P18505GABA A receptor alpha-1/beta-1/gamma-2Gamma-aminobutyric acid receptor subunit beta-1 (GABA(A) receptor subunit beta-1)GABRB1GBRB1actual, predictedBos taurus (Bovine), Homo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
ACHB30274.7474204634.7474204638.78010.53.5605653474.9158068215427Q05901Neuronal acetylcholine receptor; alpha3/alpha6/beta2/beta3Neuronal acetylcholine receptor subunit beta-3CHRNB3ACHB3predictedHomo sapiens (Human), Rattus norvegicus (Rat)predicted
PDE3A1812753.2614328913.2574727416.19471370.6311111110.890.5897430933.323750735.01876491813641291Q14432Phosphodiesterase 3cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A)PDE3APDE3Aactual, predictedHomo sapiens (Human)actual and predicted
CCNE2165523.3099354963.3052703216.5066878360.4401408450.8973214290.6227678573.7885228045.255097546916568O96020CDK3/cyclin EG1/S-specific cyclin-E2CCNE2CCNE2actual, predictedHomo sapiens (Human)actual and predicted
CCNE1165523.3099354963.3052703216.5066878360.45817490510.6227678573.7885228045.255097546916568P24864CDK1/Cyclin EG1/S-specific cyclin-E1CCNE1 CCNECCNE1actual, predicted, predictedHomo sapiens (Human)actual and predicted
TRPV40123.4622389713.4622389717.446666667010.52.5966792284.487412991212Q9HBA0Transient receptor potential cation channel subfamily V member 4Transient receptor potential cation channel subfamily V member 4 (TrpV4) (Osm-9-like TRP channel 4) (OTRPC4) (Transient receptor potential protein 12) (TRP12) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC)TRPV4 VRL2 VROACTRPV4actual, predicted, predictedHomo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)actual and predicted
5HT3E92503.405787923.405787926.52083414310.4113256110.6957957964.1544331785.6392155731490259A5X5Y0Serotonin (5-HT) receptor5-hydroxytryptamine receptor 3E (5-HT3-E) (5-HT3E) (Serotonin receptor 3E)HTR3E5HT3Eactual, predictedHomo sapiens (Human)actual and predicted
5HT3D92503.405787923.405787926.52083414310.4113256110.6957957964.1544331785.6392155731490259Q70Z44Serotonin (5-HT) receptor5-hydroxytryptamine receptor 3D (5-HT3-D) (5-HT3D) (Serotonin receptor 3D)HTR3D5HT3Dactual, predictedHomo sapiens (Human)actual and predicted
5HT3C92503.405787923.405787926.52083414310.4113256110.6957957964.1544331785.6392155731490259Q8WXA8Serotonin (5-HT) receptor5-hydroxytryptamine receptor 3C (5-HT3-C) (5-HT3C) (Serotonin receptor 3C)HTR3C5HT3Cactual, predictedHomo sapiens (Human)actual and predicted
ADCY70374.1559347094.1559347096.9893928110.6666666670.8333333337.5501833436.94086712535137P51828Adenylate cyclaseAdenylate cyclase type 7 (EC 4.6.1.1) (ATP pyrophosphate-lyase 7) (Adenylate cyclase type VII) (Adenylyl cyclase 7)ADCY7 KIAA0037ADCY7predictedHomo sapiens (Human)predicted
RAMP10624.7505543034.7505543039.19010.53.2224418714.5942707897862O60894Amylin receptor AMY1, CALCR/RAMP1Receptor activity-modifying protein 1 (Calcitonin-receptor-like receptor activity-modifying protein 1) (CRLR activity-modifying protein 1)RAMP1RAMP1predictedHomo sapiens (Human), Rattus norvegicus (Rat)predicted
CCNA1228013.1272245473.1260448038.3235606270.39813689810.5190866752.6173000014.5029860141305823P78396CDK2/Cyclin A1Cyclin-A1CCNA1CCNA1actual, predicted, predictedHomo sapiens (Human)actual and predicted
PEN21545933.9000269583.9000269586.513107071110.5847009233.3006855994.925294736148504608Q9NZ42Gamma-secretaseGamma-secretase subunit PEN-2 (Presenilin enhancer protein 2)PSENEN PEN2 MDS033PEN2actual, predicted, predictedHomo sapiens (Human)actual and predicted
NICA1545933.0818657533.0800353146.51310707110.1694018450.5847009233.3006855994.925294736148504608Q92542Gamma-secretaseNicastrinNCSTN KIAA0253 UNQ1874/PRO4317NICAactual, predictedHomo sapiens (Human)actual and predicted
APH1A1545933.0818657533.0800353146.51310707110.1694018450.5847009233.3006855994.925294736148504608Q96BI3Gamma-secretaseGamma-secretase subunit APH-1A (APH-1a) (Aph-1alpha) (Presenilin-stabilization factor)APH1A PSF CGI-78 UNQ579/PRO1141APH1Aactual, predictedHomo sapiens (Human)actual and predicted
APH1B1545933.0818657533.0800353146.51310707110.1694018450.5847009233.3006855994.925294736148504608Q8WW43Gamma-secretaseGamma-secretase subunit APH-1B (APH-1b) (Aph-1beta) (Presenilin-stabilization factor-like)APH1B PSFL UNQ688/PRO1328APH1Bactual, predictedHomo sapiens (Human)actual and predicted
KPB2052.9398638872.9398638876.770039216010.52.2048979154.313287962125P46019Phosphorylase kinasePhosphorylase b kinase regulatory subunit alpha, liver isoform (Phosphorylase kinase alpha L subunit)PHKA2 PHKLA PYKKPB2predictedHomo sapiens (Human)predicted
KPB1052.9398638872.9398638876.770039216010.52.2048979154.313287962125P46020Phosphorylase kinasePhosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform (Phosphorylase kinase alpha M subunit)PHKA1 PHKAKPB1predictedHomo sapiens (Human)predicted
KPBB052.9398638872.9398638876.770039216010.52.2048979154.313287962125Q93100Phosphorylase kinasePhosphorylase b kinase regulatory subunit beta (Phosphorylase kinase subunit beta)PHKBKPBBpredictedHomo sapiens (Human)predicted
ANPRB0225.7223301055.7223301057.8310.9090909090.95454545512.426087398.2710797323322P20594Atrial natriuretic peptide receptorAtrial natriuretic peptide receptor 2 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type B) (ANP-B) (ANPR-B) (NPR-B) (Guanylate cyclase B) (GC-B)NPR2 ANPRBANPRBpredictedHomo sapiens (Human)predicted
NCOR2401924.4932333393.8845596376.862452849110.6764455783.6673553275.442711869258196Q9Y618Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)Nuclear receptor corepressor 2 (N-CoR2) (CTG repeat protein 26) (SMAP270) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (T3 receptor-associating factor) (TRAC) (Thyroid-, retinoic-acid-receptor-associated corepressor)NCOR2 CTG26NCOR2actual, actual, predictedHomo sapiens (Human)actual and predicted
DBF4A0252.8956348012.8956348016.716164799010.52.17172614.2985449342525Q9UBU7CDC7/DBF4 (Cell division cycle 7-related protein kinase/Activator of S phase kinase)Protein DBF4 homolog A (Activator of S phase kinase) (Chiffon homolog A) (DBF4-type zinc finger-containing protein 1)DBF4 ASK DBF4A ZDBF1DBF4ApredictedHomo sapiens (Human)predicted
CDC799882.8956348012.8956348016.716164799110.5384036732.2255695634.4241713291103997O00311CDC7/DBF4 (Cell division cycle 7-related protein kinase/Activator of S phase kinase)Cell division cycle 7-related protein kinase (CDC7-related kinase) (HsCdc7) (huCdc7) (EC 2.7.11.1)CDC7 CDC7L1CDC7actual, predicted, predictedHomo sapiens (Human)actual and predicted
NPM0262.7024365022.7024365026.946923077010.52.0268273774.2341455012826P06748NPM/ALK (Nucleophosmin/ALK tyrosine kinase receptor)Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Nucleolar protein NO38) (Numatrin)NPM1 NPMNPMpredictedHomo sapiens (Human)predicted
MCHR20324.1277919654.1277919656.1509677420.03225806510.5161290323.271853634.816790876232Q969V1Melanin-concentrating hormone receptorMelanin-concentrating hormone receptor 2 (MCH receptor 2) (MCH-R2) (MCHR-2) (G-protein coupled receptor 145) (GPRv17) (MCH-2R) (MCH2) (MCH2R)MCHR2 GPR145 SLTMCHR2predictedHomo sapiens (Human)predicted
TF163992.7886054332.7886054336.8765435970.9687510.6041666672.8623270884.885678494437399P13726Coagulation factor IIITissue factor (TF) (Coagulation factor III) (Thromboplastin) (CD antigen CD142)F3TFactual, predicted, predictedHomo sapiens (Human)actual and predicted
IL61123.6371316963.5857862767.90913379310.4615384620.7307692315.2569247116.0841721041313P05231Interleukin-6Interleukin-6 (IL-6) (B-cell stimulatory factor 2) (BSF-2) (CTL differentiation factor) (CDF) (Hybridoma growth factor) (Interferon beta-2) (IFN-beta-2)IL6 IFNB2IL6actual, predictedHomo sapiens (Human)actual and predicted
ROCK22925482.6238920422.623885176.42107280.9788707810.5460904152.4011023654.51523344933132577O75116Rho-associated protein kinaseRho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, coiled-coil-containing protein kinase 2) (Rho-associated, coiled-coil-containing protein kinase II) (ROCK-II) (p164 ROCK-2)ROCK2 KIAA0619ROCK2actual, predicted, predictedHomo sapiens (Human), Rattus norvegicus (Rat)actual and predicted
AURKB3633932.7134657082.7134657088.310.9972052110.5489006762.4208566564.53484836743273429Q96GD4Aurora kinase B/Inner centromere proteinAurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (ARK-2) (Aurora-related kinase 2) (STK-1) (Serine/threonine-protein kinase 12) (Serine/threonine-protein kinase 5) (Serine/threonine-protein kinase aurora-B)AURKB AIK2 AIM1 AIRK2 ARK2 STK1 STK12 STK5AURKBactual, predicted, predictedHomo sapiens (Human)actual and predicted
S40A10395.2394745735.2394745736.794785609010.53.929605935.0798248583939Q9NP59Solute carrier family 40 member 1Solute carrier family 40 member 1 (Ferroportin-1) (Iron-regulated transporter 1)SLC40A1 FPN1 IREG1 SLC11A3 MSTP079S40A1predictedHomo sapiens (Human)predicted
MOGT20393.4926926273.4926926277.06517094010.52.619519474.4975642094739Q3SYC22-acylglycerol O-acyltransferase 22-acylglycerol O-acyltransferase 2 (EC 2.3.1.22) (Acyl-CoA:monoacylglycerol acyltransferase 2) (MGAT2) (hMGAT2) (Diacylglycerol O-acyltransferase candidate 5) (hDC5) (Diacylglycerol acyltransferase 2-like protein 5) (Monoacylglycerol O-acyltransferase 2)MOGAT2 DC5 DGAT2L5MOGT2predictedHomo sapiens (Human), Mus musculus (Mouse)predicted
ITA21182.6756875412.6845241297.962110.5263157892.3409421124.4006677772119P17301Integrin alpha-2Integrin alpha-2 (CD49 antigen-like family member B) (Collagen receptor) (Platelet membrane glycoprotein Ia) (GPIa) (VLA-2 subunit alpha) (CD antigen CD49b)ITGA2 CD49BITA2actual, predicted, predictedHomo sapiens (Human)actual and predicted
NCOR12742.7299546672.7299546676.5728907910.1578947370.5789473682.8825767994.7696340128076O75376Histone deacetylase 3/NCoR1Nuclear receptor corepressor 1 (N-CoR) (N-CoR1)NCOR1 KIAA1047NCOR1actual, predictedHomo sapiens (Human)actual and predicted
CFAD0182.6331425652.6331425657.157222222010.51.9748569234.2110475221818P00746Complement factor DComplement factor D (EC 3.4.21.46) (Adipsin) (C3 convertase activator) (Properdin factor D)CFD DF PFDCFADpredictedHomo sapiens (Human)predicted
CBPB20224.0631704284.0631704286.697495544010.53.0473778214.6877234762722Q96IY4Carboxypeptidase B2 isoform ACarboxypeptidase B2 (EC 3.4.17.20) (Carboxypeptidase U) (CPU) (Plasma carboxypeptidase B) (pCPB) (Thrombin-activable fibrinolysis inhibitor) (TAFI)CPB2CBPB2predictedHomo sapiens (Human)predicted
M3K140362.9237254362.9237254367.821235567010.52.1927940774.3079084793736Q99558Mitogen-activated protein kinase kinase kinase 14Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF-kappa-beta-inducing kinase) (HsNIK) (Serine/threonine-protein kinase NIK)MAP3K14 NIKM3K14predictedHomo sapiens (Human)predicted
KHK0163.1304056413.1304056416.40806062500.8750.43752.0255012753.9601352141716P50053KetohexokinaseKetohexokinase (EC 2.7.1.3) (Hepatic fructokinase)KHKKHKpredictedHomo sapiens (Human)predicted
LPAR6083.7734964053.7734964057.005625010.52.8301223044.591165468168P43657Lysophosphatidic acid receptor 6Lysophosphatidic acid receptor 6 (LPA receptor 6) (LPA-6) (Oleoyl-L-alpha-lysophosphatidic acid receptor) (P2Y purinoceptor 5) (P2Y5) (Purinergic receptor 5) (RB intron encoded G-protein coupled receptor)LPAR6 P2RY5LPAR6predictedHomo sapiens (Human)predicted
SC6A71143.1990025713.0456692246.976666667010.52.3992519284.3996675241515Q99884Sodium-dependent proline transporterSodium-dependent proline transporter (Solute carrier family 6 member 7)SLC6A7 PROTSC6A7actual, predictedHomo sapiens (Human)actual and predicted
GPR880423.5980565693.5980565696.928685412010.52.6985424274.5326855234242Q9GZN0Probable G-protein coupled receptor 88Probable G-protein coupled receptor 88 (Striatum-specific G-protein coupled receptor)GPR88 STRGGPR88predictedHomo sapiens (Human)predicted
P2Y100113.2485902913.2485902916.69181818200.9090909090.4545454552.1968580564.1131664612111O00398Putative P2Y purinoceptor 10Putative P2Y purinoceptor 10 (P2Y10) (P2Y-like receptor)P2RY10P2Y10predictedHomo sapiens (Human), Mus musculus (Mouse)predicted
OGRL10133.6594459223.6594459227.67307692300.8461538460.4230769232.3409373534.0403281281313Q5TC84Opioid growth factor receptor-like protein 1Opioid growth factor receptor-like protein 1OGFRL1OGRL1predictedHomo sapiens (Human)predicted
ACATN0663.5003017463.5003017468.706919192010.52.625226314.5001005826866O00400Acetyl-coenzyme A transporter 1Acetyl-coenzyme A transporter 1 (AT-1) (Acetyl-CoA transporter 1) (Solute carrier family 33 member 1)SLC33A1 ACATN AT1ACATNpredictedHomo sapiens (Human)predicted
Table contains the actual and predicted P53 scores for each target calculated by decision trees and random forest classification and regression algorithms, so as combined indexes based in all the methods predicting P53 activity. It also contains the average potency value for each target of all considered P53 active molecules.

 

 

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