| 1a | Replicase polyprotein 1a | 5.146502 | 101 | actual | Human coronavirus NL63 (HCoV-NL63) - Human SARS coronavirus (SARS-CoV) (Severe acute respiratory syndrome coronavirus) | virus | Enzyme |
| 1MB.92 | Histone deacetylase | 4.430808 | 16 | actual&Predicted | Cryptosporidium parvum | protozoan | HDAC class I |
| 56k.08 | Histone deacetylase | 4.546984 | 18 | actual&Predicted | Cryptosporidium parvum | protozoan | HDAC class I |
| Abca1 | Phospholipid-transporting ATPase ABCA1 | 5.349389 | 19 | predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | ABCA subfamily |
| ABCB1 | ATP-dependent translocase ABCB1 - Multidrug resistance protein 1 | 3.132702 | 284 | actual&Predicted | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) - Homo sapiens (Human) - Rattus norvegicus (Rat) | widespread | ABCB subfamily |
| Abcb11 | Bile salt export pump | 3.236667 | 57 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | ABCB subfamily |
| Abcc2 | Canalicular multispecific organic anion transporter 1 | 2.843115 | 50 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | ABCC subfamily |
| ABCC4 | Multidrug resistance-associated protein 4 | 2.810116 | 21 | actual&Predicted | Homo sapiens (Human) | mammals | ABCC subfamily |
| ABL1 | Tyrosine-protein kinase ABL1 | 2.683549 | 221 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Tyrosine protein kinase Abl family |
| Ace | Angiotensin-converting enzyme | 2.357864 | 30 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Oryctolagus cuniculus (Rabbit) - Rattus norvegicus (Rat) | mammals | Metallo protease M2 family |
| ACKR3 | Atypical chemokine receptor 3 | 2.689827 | 18 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | CXC chemokine receptor |
| ADAM17 | Disintegrin and metalloproteinase domain-containing protein 17 | 2.305197 | 26 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) - Sus scrofa (Pig) | mammals | Metallo protease M12B subfamily |
| ADCY1 | Adenylate cyclase type 1 | 3.151987 | 11 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) | mammals | Enzyme |
| Adcy2 | Adenylate cyclase type 2 | 3.34193 | 12 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Lyase |
| ADCY3 | Adenylate cyclase type 3 | 3.359353 | 11 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Enzyme |
| Adcy4 | Adenylate cyclase type 4 | 3.359353 | 11 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Lyase |
| ADCY5 | Adenylate cyclase type 5 | 3.257928 | 12 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Lyase |
| ADCY6 | Adenylate cyclase type 6 | 3.359353 | 11 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Lyase |
| ADCY7 | Adenylate cyclase type 7 | 3.595316 | 9 | predicted | Homo sapiens (Human) | mammals | Lyase |
| ADCY8 | Adenylate cyclase type 8 | 3.359353 | 11 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Lyase |
| ADCY9 | Adenylate cyclase type 9 | 3.594628 | 9 | predicted | Homo sapiens (Human) | mammals | Enzyme |
| Adcyap1r1 | Pituitary adenylate cyclase-activating polypeptide type I receptor | 3.748485 | 3 | predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Unclassified protein |
| agrA | Accessory gene regulator protein A | 2.752429 | 2 | actual&Predicted | Staphylococcus aureus | bacteria | Unclassified protein |
| Agtr1 | Type-1A angiotensin II receptor | 3.140119 | 164 | actual&Predicted | Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Angiotensin receptor |
| AGTR1 | Type-1 angiotensin II receptor | 3.046763 | 214 | actual&Predicted | Bos taurus (Bovine) - Cavia porcellus (Guinea pig) - Homo sapiens (Human) - Oryctolagus cuniculus (Rabbit) - Sus scrofa (Pig) | mammals | Angiotensin receptor |
| Agtr1b | Type-1B angiotensin II receptor | 3.126434 | 168 | actual&Predicted | Rattus norvegicus (Rat) | mammals | Angiotensin receptor |
| Agtr2 | Type-2 angiotensin II receptor | 3.136367 | 202 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Angiotensin receptor |
| AHR | Aryl hydrocarbon receptor | 2.190074 | 12 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Oryctolagus cuniculus (Rabbit) - Rattus norvegicus (Rat) | mammals | Transcription factor |
| AKT1 | RAC-alpha serine/threonine-protein kinase | 2.622901 | 263 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | AGC protein kinase AKT family |
| AKT2 | RAC-beta serine/threonine-protein kinase | 2.651303 | 113 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | AGC protein kinase AKT family |
| ALB | Serum albumin | 2.651308 | 53 | actual&Predicted | Bos taurus (Bovine) - Equus caballus (Horse) - Homo sapiens (Human) - Mus musculus (Mouse) - Oryctolagus cuniculus (Rabbit) - Rattus norvegicus (Rat) | mammals | Secreted protein |
| ampC | Beta-lactamase | 2.164329 | 98 | actual&Predicted | Citrobacter freundii - Enterobacter cloacae - Escherichia coli (strain K12) - Morganella morganii (Proteus morganii) - Providencia stuartii - Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) - Serratia marcescens | bacteria | Hydrolase |
| amyS | Alpha-amylase | 3.64929 | 1 | predicted | Bacillus licheniformis - Bacillus subtilis (strain 168) - Geobacillus stearothermophilus (Bacillus stearothermophilus) - Tenebrio molitor (Yellow mealworm beetle) | widespread | Hydrolase |
| ANXA2 | Annexin A2 | 2.119144 | 1 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) | mammals | Annexin |
| APC | Adenomatous polyposis coli protein | 3.966674 | 5 | predicted | Homo sapiens (Human) | mammals | Other cytosolic protein |
| APEX1 | DNA-(apurinic or apyrimidinic site) lyase | 2.294566 | 174 | actual&Predicted | Homo sapiens (Human) | mammals | Enzyme |
| APH1A | Gamma-secretase subunit APH-1A | 2.904375 | 218 | actual&Predicted | Homo sapiens (Human) | mammals | Enzyme |
| APH1B | Gamma-secretase subunit APH-1B | 2.904375 | 218 | actual&Predicted | Homo sapiens (Human) | mammals | Enzyme |
| APLNR | Apelin receptor | 3.507265 | 25 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Neuropeptide receptor |
| AR | Androgen receptor | 2.336664 | 140 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Nuclear hormone receptor subfamily 3 group C member 4 |
| ATAD5 | ATPase family AAA domain-containing protein 5 | 2.348577 | 323 | actual&Predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| ATXN2 | Ataxin-2 | 2.123454 | 211 | actual&Predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| AURKA | Aurora kinase A | 2.299265 | 186 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Other protein kinase AUR family |
| Avpr1a | Vasopressin V1a receptor | 2.821359 | 117 | actual&Predicted | Homo sapiens (Human) - Microtus ochrogaster (Prairie vole) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Vasopressin and oxytocin receptor |
| AVPR1B | Vasopressin V1b receptor | 2.82317 | 58 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Vasopressin and oxytocin receptor |
| AVPR2 | Vasopressin V2 receptor | 2.924896 | 106 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Rattus norvegicus (Rat) - Sus scrofa (Pig) | mammals | Vasopressin and oxytocin receptor |
| BACE1 | Beta-secretase 1 | 2.557365 | 226 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Aspartic protease A1A subfamily |
| Bace2 | Beta-secretase 2 | 2.467508 | 22 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Aspartic protease A1A subfamily, Hydrolase |
| BCL2 | Apoptosis regulator Bcl-2 | 4.553418 | 1397 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Bcl-2 family |
| Bcl2l1 | Bcl-2-like protein 1 | 4.384114 | 840 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Bcl-2 family |
| BCL6 | B-cell lymphoma 6 protein | 3.001738 | 2 | actual&Predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| BDKRB1 | B1 bradykinin receptor | 2.627016 | 29 | actual&Predicted | Canis lupus familiaris (Dog) (Canis familiaris) - Homo sapiens (Human) - Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) - Macaca mulatta (Rhesus macaque) - Mus musculus (Mouse) - Oryctolagus cuniculus (Rabbit) - Rattus norvegicus (Rat) | mammals | Bradykinin receptor |
| BDKRB2 | B2 bradykinin receptor | 2.934671 | 41 | actual&Predicted | Cavia porcellus (Guinea pig) - Homo sapiens (Human) - Oryctolagus cuniculus (Rabbit) - Rattus norvegicus (Rat) | mammals | Bradykinin receptor |
| BIRC2 | Baculoviral IAP repeat-containing protein 2 | 2.921917 | 91 | actual&Predicted | Homo sapiens (Human) | mammals | Enzyme |
| BIRC3 | Baculoviral IAP repeat-containing protein 3 | 3.383159 | 55 | actual&Predicted | Homo sapiens (Human) | mammals | Enzyme |
| bla; | Beta-lactamase TEM | 2.208715 | 3 | actual&Predicted | Escherichia coli | bacteria | Hydrolase |
| botA | Botulinum neurotoxin type A | 2.553972 | 16 | actual&Predicted | Clostridium botulinum - Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A) | bacteria | Metallo protease M27 family |
| BRCA1 | Breast cancer type 1 susceptibility protein | 2.275611 | 43 | actual&Predicted | Homo sapiens (Human) | mammals | Enzyme |
| C3 | Complement C3 | 4.142536 | 14 | predicted | Homo sapiens (Human) | mammals | Secreted protein |
| C3AR1 | C3a anaphylatoxin chemotactic receptor | 2.406052 | 7 | predicted | Homo sapiens (Human) | mammals | Anaphylatoxin receptor |
| C5AR1 | C5a anaphylatoxin chemotactic receptor 1 | 2.82586 | 29 | actual&Predicted | Canis lupus familiaris (Dog) (Canis familiaris) - Cavia porcellus (Guinea pig) - Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Anaphylatoxin receptor |
| CACNA1B | Voltage-dependent N-type calcium channel subunit alpha-1B | 3.353746 | 111 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Voltage-gated calcium channel |
| CaFKS1 | 1,3-beta-D-glucan synthase catalytic subunit | 2.339996 | 11 | actual&Predicted | Candida albicans (Yeast) | fungi | Enzyme |
| Calca | Calcitonin gene-related peptide 1 | 3.094506 | 6 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Secreted protein |
| CALCRL | Calcitonin gene-related peptide type 1 receptor | 2.663307 | 36 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Calcitonin gene-related peptide receptor |
| CAPN1 | Calpain-1 catalytic subunit | 2.527879 | 32 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) - Sus scrofa (Pig) | mammals | Cysteine protease C2 family |
| Casp1 | Caspase-1 | 2.071319 | 22 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Cysteine protease C14 family |
| CAV1 | Caveolin-1 | 3.880453 | 1 | predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| CBX6 | Chromobox protein homolog 6 | 5.232632 | 5 | predicted | Homo sapiens (Human) | mammals | Chromodomain |
| CBX7 | Chromobox protein homolog 7 | 2.920815 | 7 | predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Chromodomain |
| Cckar | Cholecystokinin receptor type A | 3.014005 | 195 | actual&Predicted | Cavia porcellus (Guinea pig) - Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Cholecystokinin receptor |
| CCKBR | Gastrin/cholecystokinin type B receptor | 3.016465 | 210 | actual&Predicted | Bos taurus (Bovine) - Canis lupus familiaris (Dog) (Canis familiaris) - Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Cholecystokinin receptor |
| CCL5 | C-C motif chemokine 5 | 2.315725 | 5 | predicted | Homo sapiens (Human) | mammals | CC chemokine receptor |
| CCNB1 | G2/mitotic-specific cyclin-B1 | 2.286669 | 65 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Other cytosolic protein |
| CD2 | T-cell surface antigen CD2 | 5.298228 | 6 | predicted | Homo sapiens (Human) | mammals | Surface antigen |
| CD274 | Programmed cell death 1 ligand 1 | 2.574561 | 2 | actual&Predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| CD47 | Leukocyte surface antigen CD47 | 4.36385 | 3 | predicted | Homo sapiens (Human) | mammals | Adhesion, Membrane receptor |
| CD58 | Lymphocyte function-associated antigen 3 | 5.056392 | 3 | predicted | Homo sapiens (Human) | mammals | Other membrane protein |
| CELA1 | Chymotrypsin-like elastase family member 1 | 2.63328 | 6 | actual&Predicted | Homo sapiens (Human) - Sus scrofa (Pig) | mammals | Serine protease S1A subfamily |
| Cela2a | Chymotrypsin-like elastase family member 2A | 2.61896 | 6 | actual&Predicted | Rattus norvegicus (Rat) - Sus scrofa (Pig) | mammals | Serine protease S1A subfamily |
| CHRNA10 | Neuronal acetylcholine receptor subunit alpha-10 | 1.777076 | 21 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Nicotinic acetylcholine receptor alpha subunit |
| Chrna2 | Neuronal acetylcholine receptor subunit alpha-2 | 1.770033 | 11 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Nicotinic acetylcholine receptor alpha subunit |
| Chrna3 | Neuronal acetylcholine receptor subunit alpha-3 | 1.98913 | 112 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Nicotinic acetylcholine receptor alpha subunit |
| Chrna4 | Neuronal acetylcholine receptor subunit alpha-4 | 1.898547 | 53 | actual&Predicted | Gallus gallus (Chicken) - Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Nicotinic acetylcholine receptor alpha subunit |
| Chrna6 | Neuronal acetylcholine receptor subunit alpha-6 | 1.802724 | 41 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Nicotinic acetylcholine receptor alpha subunit |
| CHRNA7 | Neuronal acetylcholine receptor subunit alpha-7 | 1.840311 | 50 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Macaca mulatta (Rhesus macaque) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Nicotinic acetylcholine receptor alpha subunit |
| Chrna9 | Neuronal acetylcholine receptor subunit alpha-9 | 1.779226 | 21 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Nicotinic acetylcholine receptor alpha subunit |
| Chrnb2 | Neuronal acetylcholine receptor subunit beta-2 | 1.923394 | 73 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Nicotinic acetylcholine receptor beta subunit |
| Chrnb3 | Neuronal acetylcholine receptor subunit beta-3 | 1.736891 | 6 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Nicotinic acetylcholine receptor beta subunit |
| Chrnb4 | Neuronal acetylcholine receptor subunit beta-4 | 1.97129 | 96 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Nicotinic acetylcholine receptor beta subunit |
| Chrne | Acetylcholine receptor subunit epsilon | 2.341397 | 1 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Nicotinic acetylcholine receptor epsilon subunit |
| CMA1 | Chymase | 2.311382 | 20 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Serine protease S1A subfamily |
| CPA1 | Carboxypeptidase A1 | 2.391605 | 1 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) | mammals | Metallo protease M14A subfamily |
| CRHR1 | Corticotropin-releasing factor receptor 1 | 3.322265 | 383 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Corticotropin releasing factor receptor |
| Crhr2 | Corticotropin-releasing factor receptor 2 | 2.702141 | 88 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Corticotropin releasing factor receptor |
| CRK | Adapter molecule crk | 5.364694 | 3 | actual&Predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| CTRA | Chymotrypsinogen A | 2.672555 | 16 | actual&Predicted | Bos taurus (Bovine) | mammals | Serine protease S1A subfamily |
| CTRC | Chymotrypsin-C | 2.801132 | 20 | actual&Predicted | Homo sapiens (Human) | mammals | Serine protease S1A subfamily |
| CTRL | Chymotrypsin-like protease CTRL-1 | 3.737325 | 4 | actual&Predicted | Homo sapiens (Human) | mammals | Serine protease S1A subfamily |
| Ctsb | Cathepsin B | 2.483321 | 47 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Cysteine protease C1A family |
| CTSD | Cathepsin D | 2.735303 | 60 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) | mammals | Aspartic protease A1A subfamily |
| CTSE | Cathepsin E | 3.609458 | 5 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Aspartic protease A1A subfamily |
| CTSG | Cathepsin G | 2.388686 | 10 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Serine protease S1A subfamily |
| Ctsh | Pro-cathepsin H - Pro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H | 2.651933 | 5 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Cysteine protease C1A family, Enzyme, Hydrolase |
| Ctsk | Cathepsin K | 2.375897 | 32 | actual&Predicted | Canis lupus familiaris (Dog) (Canis familiaris) - Homo sapiens (Human) - Mus musculus (Mouse) - Oryctolagus cuniculus (Rabbit) - Rattus norvegicus (Rat) | mammals | Cysteine protease C1A family |
| Ctsl | Cathepsin L1 | 2.427165 | 49 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Cysteine protease C1A family |
| Ctss | Cathepsin S | 2.374385 | 38 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Cysteine protease C1A family |
| Cxcr4 | C-X-C chemokine receptor type 4 | 2.605522 | 38 | actual&Predicted | Homo sapiens (Human) - Macaca mulatta (Rhesus macaque) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | CXC chemokine receptor |
| Cyp1a2 | Cytochrome P450 1A2 | 2.108485 | 194 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Cytochrome P450 1A1, Cytochrome P450 1A2 |
| CYP2C19 | Cytochrome P450 2C19 | 2.172638 | 199 | actual&Predicted | Homo sapiens (Human) | mammals | Cytochrome P450 2C19 |
| CYP2C9 | Cytochrome P450 2C9 | 2.239767 | 228 | actual&Predicted | Homo sapiens (Human) | mammals | Cytochrome P450 2C9 |
| CYP2D6 | Cytochrome P450 2D6 | 2.197044 | 290 | actual&Predicted | Homo sapiens (Human) | mammals | Cytochrome P450 2D6 |
| CYP3A4 | Cytochrome P450 3A4 | 2.11263 | 423 | actual&Predicted | Homo sapiens (Human) | mammals | Cytochrome P450 3A4 |
| CYSP | Cruzipain - Trophozoite cysteine proteinase | 2.17436 | 107 | actual&Predicted | Plasmodium falciparum - Trypanosoma cruzi | protozoan | Cysteine protease C1 family, Cysteine protease C1A family |
| D0E0C1 | Sodium channel protein | 3.744687 | 1 | predicted | Periplaneta americana (American cockroach) (Blatta americana) | arthropoda | Voltage-gated sodium channel |
| DCUN1D1 | DCN1-like protein 1 | 3.524911 | 32 | predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| DEFA1 | Neutrophil defensin 1 | 4.911698 | 5 | predicted | Homo sapiens (Human) | mammals | Secreted protein |
| Dpp4 | Dipeptidyl peptidase 4 | 2.097853 | 46 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) - Sus scrofa (Pig) | mammals | Serine protease S9B subfamily |
| DRD2 | D(2) dopamine receptor | 2.641715 | 992 | actual&Predicted | Bos taurus (Bovine) - Canis lupus familiaris (Dog) (Canis familiaris) - Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops) - Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Dopamine receptor |
| dsbA | Thiol:disulfide interchange protein DsbA | 3.116421 | 6 | predicted | Escherichia coli (strain K12) | bacteria | Unclassified protein |
| DVL2 | Segment polarity protein dishevelled homolog DVL-2 | 4.893322 | 4 | predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| ECE1 | Endothelin-converting enzyme 1 | 2.30123 | 20 | predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Metallo protease M13 family |
| EDNRA | Endothelin-1 receptor | 2.422985 | 101 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) - Sus scrofa (Pig) | mammals | Endothelin receptor |
| Ednrb | Endothelin receptor type B | 2.502461 | 62 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Mus musculus (Mouse) - Oryctolagus cuniculus (Rabbit) - Rattus norvegicus (Rat) - Sus scrofa (Pig) | mammals | Endothelin receptor |
| EED | Polycomb protein EED | 2.678052 | 12 | actual&Predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| EGFR | Epidermal growth factor receptor | 2.835479 | 582 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Tyrosine protein kinase EGFR family |
| EIF4A1 | Eukaryotic initiation factor 4A-I | 2.558012 | 1 | predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Oryctolagus cuniculus (Rabbit) | mammals | Hydrolase |
| Eif4a2 | Eukaryotic initiation factor 4A-II | 3.401106 | 1 | predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Enzyme, Hydrolase |
| ELANE | Neutrophil elastase | 2.405196 | 82 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Serine protease S1A subfamily |
| env | Envelope glycoprotein gp160 | 4.87554 | 6 | actual&Predicted | Human immunodeficiency virus 1 | virus | Surface antigen |
| env | Envelope glycoprotein gp160 [Cleaved into: Surface protein gp120 | 3.245049 | 12 | actual&Predicted | Human immunodeficiency virus 1 | virus | Surface antigen |
| env | Envelope glycoprotein - Envelope glycoprotein gp160 - Envelope glycoprotein gp70 | 2.736121 | 26 | actual&Predicted | Bovine leukemia virus (isolate Japanese BLV-1) (BLV) - Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1) - Human immunodeficiency virus type 1 group M subtype B (isolate BRU/LAI) (HIV-1) - Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) (HIV-1) - Human immunodeficiency virus type 1 group M subtype B (isolate SF162) (HIV-1) - Human immunodeficiency virus type 1 group M subtype B (isolate YU-2) (HIV-1) - Maedi visna virus (strain 1514) (MVV) (Visna lentivirus) - Mouse mammary tumor virus (strain GR) (MMTV) | virus | Surface antigen |
| EPHA2 | Ephrin type-A receptor 2 | 2.366329 | 95 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Transferase, Tyrosine protein kinase Eph family |
| EPHA4 | Ephrin type-A receptor 4 | 2.515344 | 45 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Tyrosine protein kinase Eph family |
| EPHB2 | Ephrin type-B receptor 2 | 2.574164 | 46 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Tyrosine protein kinase Eph family |
| EPHB4 | Ephrin type-B receptor 4 | 2.54199 | 79 | actual&Predicted | Homo sapiens (Human) | mammals | Tyrosine protein kinase Eph family |
| EPOR | Erythropoietin receptor | 3.440077 | 11 | predicted | Homo sapiens (Human) | mammals | Membrane receptor |
| ERBB2 | Receptor tyrosine-protein kinase erbB-2 | 2.849024 | 317 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Tyrosine protein kinase EGFR family |
| ESR1 | Estrogen receptor | 3.060952 | 350 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Mus musculus (Mouse) - Ovis aries (Sheep) - Rattus norvegicus (Rat) | mammals | Nuclear hormone receptor subfamily 3 group A member 1 |
| Esr2 | Estrogen receptor beta | 3.020173 | 238 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Mus musculus (Mouse) - Ovis aries (Sheep) - Rattus norvegicus (Rat) | mammals | Nuclear hormone receptor subfamily 3 group A member 2, Unclassified protein |
| F10 | Coagulation factor X | 2.492246 | 200 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Oryctolagus cuniculus (Rabbit) - Rattus norvegicus (Rat) | mammals | Serine protease S1A subfamily |
| F11 | Coagulation factor XI | 2.8001 | 68 | predicted | Homo sapiens (Human) | mammals | Serine protease S1A subfamily |
| F12 | Coagulation factor XII | 2.693239 | 45 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) | mammals | Serine protease S1A subfamily |
| F13A1 | Coagulation factor XIII A chain | 1.844286 | 3 | actual&Predicted | Homo sapiens (Human) | mammals | Protein-glutamine glutamyl-transferase |
| F2 | Prothrombin | 2.468271 | 192 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Serine protease S1A subfamily |
| F2R | Proteinase-activated receptor 1 | 2.984497 | 78 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Protease-activated receptor |
| FCGRT | IgG receptor FcRn large subunit p51 | 3.59549 | 13 | predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| FLT1 | Vascular endothelial growth factor receptor 1 | 2.514531 | 134 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Tyrosine protein kinase VEGFR family |
| FPR1 | fMet-Leu-Phe receptor | 2.666619 | 64 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | N-formyl methionyl peptide receptor |
| FURIN | Furin | 3.804258 | 118 | predicted | Homo sapiens (Human) | mammals | Serine protease S8B subfamily |
| GABBR1 | Gamma-aminobutyric acid type B receptor subunit 1 | 3.190783 | 24 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | GABA-B receptor |
| GABBR2 | Gamma-aminobutyric acid type B receptor subunit 2 | 3.290889 | 22 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | GABA-B receptor |
| gag | Structural capsid protein | 2.71198 | 1 | predicted | Human immunodeficiency virus 1 | virus | Structural protein |
| gag-pro | Gag-Pro polyprotein | 3.742918 | 8 | actual&Predicted | Human T-cell leukemia virus 1 (strain Japan ATK-1 subtype A) (HTLV-1) | virus | Aspartic protease A2A subfamily |
| GALR1 | Galanin receptor type 1 | 2.370964 | 1 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Galanin receptor |
| Galr2 | Galanin receptor type 2 | 2.536271 | 1 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Galanin receptor |
| GBA | Lysosomal acid glucosylceramidase | 2.301891 | 102 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Enzyme |
| Gcgr | Glucagon receptor | 3.006677 | 90 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Glucagon receptor |
| GCLC | Glutamate--cysteine ligase - Glutamate--cysteine ligase catalytic subunit | 2.595802 | 1 | predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Onchocerca volvulus - Rattus norvegicus (Rat) | mammals | Ligase |
| Gipr | Gastric inhibitory polypeptide receptor | 2.779333 | 11 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Gastric inhibitory polypeptide receptor |
| Glp1r | Glucagon-like peptide 1 receptor | 2.213005 | 545 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Glucagon-like peptide receptor |
| GLP2R | Glucagon-like peptide 2 receptor | 3.478573 | 27 | predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Glucagon-like peptide receptor |
| GLS | Glutaminase kidney isoform, mitochondrial | 2.195217 | 92 | actual&Predicted | Homo sapiens (Human) | mammals | Hydrolase |
| GMNN | Geminin | 2.299658 | 517 | actual&Predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| GNAS | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | 2.239863 | 122 | actual&Predicted | Homo sapiens (Human) | mammals | Other membrane protein |
| GNRHR | Gonadotropin-releasing hormone receptor | 3.415856 | 313 | actual&Predicted | Homo sapiens (Human) - Macaca mulatta (Rhesus macaque) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | GnRH receptor |
| GP | Envelope glycoprotein | 4.720024 | 6 | actual&Predicted | Zaire ebolavirus (strain Mayinga-76) (ZEBOV) (Zaire Ebola virus) | virus | Unclassified protein |
| GRB2 | Growth factor receptor-bound protein 2 | 2.715816 | 15 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Other cytosolic protein |
| GRB7 | Growth factor receptor-bound protein 7 | 3.503726 | 5 | predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| Grin1 | Glutamate receptor ionotropic, NMDA 1 | 2.453926 | 231 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | NMDA receptor |
| Grin2a | Glutamate receptor ionotropic, NMDA 2A | 2.386677 | 145 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | NMDA receptor |
| Grin2b | Glutamate receptor ionotropic, NMDA 2B | 2.423851 | 224 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | NMDA receptor |
| Grin2c | Glutamate receptor ionotropic, NMDA 2C | 2.420398 | 189 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | NMDA receptor |
| GRIN2D | Glutamate receptor ionotropic, NMDA 2D | 2.418803 | 186 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | NMDA receptor |
| GRIN3A | Glutamate receptor ionotropic, NMDA 3A | 2.390685 | 129 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | NMDA receptor |
| GRIN3B | Glutamate receptor ionotropic, NMDA 3B | 2.390838 | 126 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | NMDA receptor |
| GRK2 | Beta-adrenergic receptor kinase 1 | 2.395665 | 9 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | AGC protein kinase BARK subfamily, Transferase |
| GRK3 | Beta-adrenergic receptor kinase 2 | 2.79405 | 8 | predicted | Bos taurus (Bovine) - Homo sapiens (Human) | mammals | AGC protein kinase BARK subfamily |
| GRK5 | G protein-coupled receptor kinase 5 | 2.226685 | 47 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Mus musculus (Mouse) | mammals | AGC protein kinase GRK subfamily |
| Grpr | Gastrin-releasing peptide receptor | 2.956734 | 3 | predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | GRP-related receptor |
| GSC1 | Beta-1,3-glucan synthase catalytic subunit 1 | 4.178128 | 49 | actual&Predicted | Candida albicans (Yeast) | fungi | Transferase |
| GSC2 | 1,3-beta-glucan synthase component GSC2 | 5.158092 | 21 | predicted | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | fungi | Transferase |
| Gsk3b | Glycogen synthase kinase-3 beta | 2.03489 | 109 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | CMGC protein kinase GSK family |
| HA | Hemagglutinin [Cleaved into: Hemagglutinin HA1 chain; Hemagglutinin HA2 chain] | 3.794101 | 5 | actual&Predicted | Influenza A virus (strain A/Aichi/2/1968 H3N2) - Influenza A virus (strain A/Puerto Rico/8/1934 H1N1) - Influenza A virus (strain A/X-31 H3N2) | virus | Surface antigen |
| HCRTR1 | Orexin receptor type 1 | 2.430458 | 77 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Orexin receptor |
| hda106 | HD2 type histone deacetylase HDA106 | 2.160829 | 3 | actual&Predicted | Zea mays (Maize) | plants | Enzyme |
| Hdac1 | Histone deacetylase 1 | 2.348416 | 184 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | HDAC class I |
| Hdac10 | Polyamine deacetylase HDAC10 | 2.368357 | 94 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | HDAC class IIb |
| Hdac11 | Histone deacetylase 11 | 2.366831 | 91 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | HDAC class IV |
| Hdac2 | Histone deacetylase 2 | 2.364637 | 116 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | HDAC class I |
| HDAC3 | Histone deacetylase 3 | 2.345275 | 112 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | HDAC class I |
| HDAC4 | Histone deacetylase 4 | 2.348844 | 102 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Enzyme, HDAC class IIa |
| HDAC5 | Histone deacetylase 5 | 2.368846 | 92 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | HDAC class IIa |
| HDAC6 | Histone deacetylase 6 | 2.35819 | 162 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | HDAC class IIb |
| Hdac7 | Histone deacetylase 7 | 2.351183 | 94 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | HDAC class IIa |
| Hdac8 | Histone deacetylase 8 | 2.365042 | 137 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | HDAC class I, HDAC class IIa |
| Hdac9 | Histone deacetylase 9 | 2.367801 | 93 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | HDAC class IIa |
| HIV-1 | HIV-1 protease | 4.366996 | 22 | actual&Predicted | Human immunodeficiency virus | virus | Enzyme |
| HIV1 | GP41 | 4.376899 | 7 | predicted | Human immunodeficiency virus 1 | virus | Unclassified protein |
| HLA-DRB1 | HLA class II histocompatibility antigen, DRB1-1 beta chain | 3.059127 | 7 | predicted | Homo sapiens (Human) | mammals | Surface antigen |
| Hsf1 | Heat shock factor protein 1 | 2.487968 | 25 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Other cytosolic protein |
| HSP90 | Heat shock protein 90 homolog - Heat shock protein HSP 90 | 3.752621 | 13 | actual&Predicted | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) - Oryctolagus cuniculus (Rabbit) | mammals | Other cytosolic protein |
| HSP90AA1 | Heat shock protein HSP 90-alpha | 2.998097 | 330 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Other cytosolic protein |
| HSP90AB1 | Heat shock protein HSP 90-beta | 3.073674 | 146 | actual&Predicted | Homo sapiens (Human) - Oryctolagus cuniculus (Rabbit) | mammals | Other cytosolic protein |
| HSPA5 | Endoplasmic reticulum chaperone BiP | 2.351109 | 37 | actual&Predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| HTR1B | 5-hydroxytryptamine receptor 1B | 2.323802 | 119 | actual&Predicted | Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) - Gorilla gorilla gorilla (Western lowland gorilla) - Homo sapiens (Human) - Mus musculus (Mouse) - Oryctolagus cuniculus (Rabbit) - Rattus norvegicus (Rat) - Sus scrofa (Pig) | mammals | Serotonin receptor |
| humanLeukemiaVirusProtease | humanLeukemiaVirusProtease | 3.466427 | 162 | actual&Predicted | Human immunodeficiency virus 1 | virus | Cysteine protease C3A subfamily |
| humanRhinovirusProtease | humanRhinovirusProtease | 3.507633 | 134 | actual&Predicted | Human rhinovirus sp. | virus | Cysteine protease C3A subfamily |
| ICAM1 | Intercellular adhesion molecule 1 | 2.988026 | 71 | actual&Predicted | Homo sapiens (Human) | mammals | Adhesion |
| IDE | Insulin-degrading enzyme | 2.594863 | 19 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Enzyme |
| IDH1 | Isocitrate dehydrogenase [NADP] cytoplasmic | 2.269525 | 285 | actual&Predicted | Homo sapiens (Human) | mammals | Oxidoreductase |
| INSR | Insulin receptor | 2.853611 | 172 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Tyrosine protein kinase InsR family |
| IRAK4 | Interleukin-1 receptor-associated kinase 4 | 2.303697 | 91 | actual&Predicted | Homo sapiens (Human) | mammals | TKL protein kinase IRAK family |
| ITGA2B | Integrin alpha-IIb | 2.093 | 8 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Membrane receptor |
| ITGA4 | Integrin alpha-4 | 2.148948 | 30 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Membrane receptor |
| ITGAL | Integrin alpha-L | 3.020499 | 69 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Adhesion, Membrane receptor |
| ITGAV | Integrin alpha-V | 2.120923 | 21 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Membrane receptor |
| ITGB2 | Integrin beta-2 | 3.062896 | 70 | actual&Predicted | Homo sapiens (Human) | mammals | Membrane receptor |
| Itgb3 | Integrin beta-3 | 2.115165 | 27 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Membrane receptor |
| ITGB5 | Integrin beta-5 | 2.335448 | 9 | actual&Predicted | Homo sapiens (Human) | mammals | Membrane receptor |
| ITGB7 | Integrin beta-7 | 2.284493 | 22 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Membrane receptor |
| Kcna1 | Potassium voltage-gated channel subfamily A member 1 | 4.040555 | 138 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Voltage-gated potassium channel |
| Kcna3 | Potassium voltage-gated channel subfamily A member 3 | 3.843733 | 164 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Voltage-gated potassium channel |
| KCNK2 | Potassium channel subfamily K member 2 | 2.70399 | 5 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Two-pore domain potassium channel |
| KDM1A | Lysine-specific histone demethylase 1A | 2.412277 | 65 | actual&Predicted | Homo sapiens (Human) | mammals | Lysine-specific demethylase |
| KDM1B | Lysine-specific histone demethylase 1B | 2.924996 | 3 | predicted | Homo sapiens (Human) | mammals | Lysine-specific demethylase |
| KDM4A | Lysine-specific demethylase 4A | 2.225149 | 77 | actual&Predicted | Homo sapiens (Human) | mammals | Jumonji domain-containing, Plant homeodomain, Tudor domain |
| KDM4C | Lysine-specific demethylase 4C | 2.113017 | 21 | actual&Predicted | Homo sapiens (Human) | mammals | Jumonji domain-containing, Plant homeodomain, Tudor domain |
| KDM5A | Lysine-specific demethylase 5A | 2.011141 | 7 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Jumonji domain-containing, Plant homeodomain |
| KEAP1 | Kelch-like ECH-associated protein 1 | 2.498885 | 33 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Unclassified protein |
| kgp | Lys-gingipain | 4.725865 | 1 | predicted | Porphyromonas gingivalis (strain ATCC 33277 / DSM 20709 / CIP 103683 / JCM 12257 / NCTC 11834 / 2561) | bacteria | Hydrolase |
| Kiss1r | KiSS-1 receptor | 3.300047 | 41 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | RF amide receptor |
| KLK1 | Kallikrein-1 | 2.802994 | 9 | actual&Predicted | Homo sapiens (Human) | mammals | Serine protease S1A subfamily |
| KLK14 | Kallikrein-14 | 2.814874 | 8 | actual&Predicted | Homo sapiens (Human) | mammals | Serine protease S1A subfamily |
| KLK2 | Kallikrein-2 | 3.38213 | 1 | predicted | Homo sapiens (Human) | mammals | Serine protease S1A subfamily |
| KLK3 | Prostate-specific antigen | 3.992522 | 22 | predicted | Homo sapiens (Human) | mammals | Serine protease S1A subfamily |
| KLK4 | Kallikrein-4 | 3.698501 | 8 | actual&Predicted | Homo sapiens (Human) | mammals | Serine protease S1A subfamily |
| KLK5 | Kallikrein-5 | 2.450898 | 7 | actual&Predicted | Homo sapiens (Human) | mammals | Serine protease S1A subfamily |
| KLK7 | Kallikrein-7 | 2.280994 | 9 | actual&Predicted | Homo sapiens (Human) | mammals | Serine protease S1A subfamily |
| KLKB1 | Plasma kallikrein | 2.629747 | 86 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Hydrolase, Serine protease, Serine protease S1A subfamily |
| Kmt2a | Histone-lysine N-methyltransferase 2A | 2.389978 | 290 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Bromodomain, Plant homeodomain, Protein methyltransferase |
| KMT5A | Histone-lysine N-methyltransferase PR-Set7 - N-lysine methyltransferase KMT5A | 3.087624 | 11 | actual&Predicted | Drosophila melanogaster (Fruit fly) - Homo sapiens (Human) | mammals | Enzyme, SET domain |
| KRAS | GTPase KRas | 3.156652 | 8 | actual&Predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| lacZ | Beta-galactosidase | 1.880763 | 5 | actual&Predicted | Aspergillus niger - Bos taurus (Bovine) - Escherichia coli - Escherichia coli (strain K12) - Felis catus (Cat) (Felis silvestris catus) - Homo sapiens (Human) - Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica) - Mus musculus (Mouse) - Rhizobium meliloti (Ensifer meliloti) (Sinorhizobium meliloti) | widespread | Enzyme, Hydrolase |
| LCK | Proto-oncogene tyrosine-protein kinase LCK - Tyrosine-protein kinase Lck | 2.482083 | 193 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Tyrosine protein kinase Src family |
| lef | Lethal factor | 2.129759 | 126 | actual&Predicted | Bacillus anthracis | bacteria | Metallo protease M34 family |
| lepB | Signal peptidase I - Signal peptidase IB | 3.986266 | 8 | predicted | Escherichia coli (strain K12) - Staphylococcus aureus | bacteria | Serine protease S26A subfamily |
| Lgals3 | Galectin-3 | 2.78462 | 6 | predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Other cytosolic protein |
| Lhcgr | Lutropin-choriogonadotropic hormone receptor | 2.753814 | 7 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Glycohormone receptor |
| lptD | LPS-assembly protein LptD | 4.97179 | 8 | predicted | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) | bacteria | Unclassified protein |
| LUCI | Coelenterazine h 2-monooxygenase - Luciferin 4-monooxygenase | 2.263174 | 117 | actual&Predicted | Aquatica lateralis (Heike firefly) (Luciola lateralis) - Photinus pyralis (Common eastern firefly) (Lampyris pyralis) - Photuris pensylvanica (Pennsylania firefly) - Renilla reniformis (Sea pansy) | arthropoda | Enzyme, Oxidoreductase |
| Mapk10 | Mitogen-activated protein kinase 10 | 2.325827 | 90 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | CMGC protein kinase JNK subfamily |
| Mapk14 | Mitogen-activated protein kinase 14 | 2.73706 | 338 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | CMGC protein kinase p38 subfamily |
| MAPK8 | Mitogen-activated protein kinase 8 | 2.20459 | 105 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | CMGC protein kinase JNK subfamily |
| MAPK9 | Mitogen-activated protein kinase 9 | 2.130102 | 99 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | CMGC protein kinase JNK subfamily |
| MAPKAPK2 | MAP kinase-activated protein kinase 2 | 2.275153 | 77 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | CAMK protein kinase MAPKAPK subfamily |
| MAPT | Microtubule-associated protein tau | 2.167214 | 304 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Other cytosolic protein |
| MC1R | Melanocyte-stimulating hormone receptor | 2.641583 | 75 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Melanocortin receptor |
| Mc3r | Melanocortin receptor 3 | 2.726922 | 67 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Melanocortin receptor |
| MC4R | Melanocortin receptor 4 | 2.853646 | 253 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Melanocortin receptor |
| MC5R | Melanocortin receptor 5 | 2.777617 | 103 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Melanocortin receptor |
| Mcl1 | Induced myeloid leukemia cell differentiation protein Mcl-1 - Induced myeloid leukemia cell differentiation protein Mcl-1 homolog | 2.744413 | 122 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Other cytosolic protein, Unclassified protein |
| Mdm2 | E3 ubiquitin-protein ligase Mdm2 | 2.871961 | 277 | actual&Predicted | Canis lupus familiaris (Dog) (Canis familiaris) - Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Ligase, Other nuclear protein |
| MDM4 | Protein Mdm4 | 2.939913 | 40 | actual&Predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| MEN1 | Menin | 2.394322 | 272 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Unclassified protein |
| Mme | Neprilysin | 2.320582 | 23 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Oryctolagus cuniculus (Rabbit) - Rattus norvegicus (Rat) - Sus scrofa (Pig) | mammals | Metallo protease M13 family |
| MMP1 | Interstitial collagenase | 2.345255 | 31 | actual&Predicted | Homo sapiens (Human) | mammals | Metallo protease M10A subfamily |
| MMP11 | Stromelysin-3 | 3.945798 | 11 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Metallo protease M10A subfamily |
| MMP13 | Collagenase 3 | 2.269832 | 28 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Hydrolase, Metallo protease M10A subfamily |
| MMP14 | Matrix metalloproteinase-14 | 2.181833 | 30 | actual&Predicted | Homo sapiens (Human) | mammals | Metallo protease M10A subfamily |
| MMP2 | 72 kDa type IV collagenase | 2.260986 | 64 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Metallo protease M10A subfamily |
| MMP7 | Matrilysin | 2.385156 | 15 | actual&Predicted | Homo sapiens (Human) | mammals | Metallo protease M10A subfamily |
| Mmp8 | Neutrophil collagenase | 2.238 | 19 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Metallo protease M10A subfamily |
| MMP9 | Matrix metalloproteinase-9 | 2.258819 | 58 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Metallo protease M10A subfamily |
| MPO | Myeloperoxidase | 1.839431 | 3 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Oxidoreductase |
| MSTN | Growth/differentiation factor 8 | 3.36937 | 5 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Secreted protein |
| mth | G-protein coupled receptor Mth | 4.496864 | 5 | predicted | Drosophila melanogaster (Fruit fly) | arthropoda | Peptide receptor (family B GPCR) |
| Mylk | Myosin light chain kinase, smooth muscle | 2.62771 | 71 | actual&Predicted | Gallus gallus (Chicken) - Homo sapiens (Human) | mammals | CAMK protein kinase MLCK family |
| NCSTN | Nicastrin | 2.904375 | 218 | actual&Predicted | Homo sapiens (Human) | mammals | Aspartic protease A22A regulatory subfamily |
| Nfe2l2 | Nuclear factor erythroid 2-related factor 2 | 2.210433 | 331 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Unclassified protein |
| Nmur1 | Neuromedin-U receptor 1 | 3.800616 | 35 | predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Neuromedin U receptor |
| Nmur2 | Neuromedin-U receptor 2 | 3.803346 | 36 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Neuromedin U receptor |
| Npffr2 | Neuropeptide FF receptor 2 | 2.236623 | 1 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | RF amide receptor |
| NPFR | Neuropeptide F receptor | 5.279989 | 1 | predicted | Drosophila melanogaster (Fruit fly) | arthropoda | Unclassified protein |
| NPR1 | Atrial natriuretic peptide receptor 1 | 3.703017 | 27 | predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Membrane receptor, Receptor guanylate cyclase |
| NPR2 | Atrial natriuretic peptide receptor 2 | 3.825625 | 1 | predicted | Bos taurus (Bovine) - Homo sapiens (Human) | mammals | Membrane receptor, Receptor guanylate cyclase |
| NPR3 | Atrial natriuretic peptide receptor 3 | 3.777601 | 6 | predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Membrane receptor |
| Npy1r | Neuropeptide Y receptor type 1 | 3.019858 | 86 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Neuropeptide Y receptor, Unclassified protein |
| Npy2r | Neuropeptide Y receptor Y2 | 3.401346 | 3 | actual&Predicted | Rattus norvegicus (Rat) | mammals | Neuropeptide Y receptor |
| NPY2R | Neuropeptide Y receptor type 2 | 3.139498 | 48 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Neuropeptide Y receptor, Unclassified protein |
| NPY4R | Neuropeptide Y receptor type 4 | 3.577024 | 30 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Neuropeptide Y receptor, Unclassified protein |
| Npy5r | Neuropeptide Y receptor type 5 | 2.530461 | 63 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Neuropeptide Y receptor |
| Nr1h4 | Bile acid receptor | 2.58515 | 50 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Nuclear hormone receptor subfamily 1 group H member 4, Unclassified protein |
| NR1I2 | Nuclear receptor subfamily 1 group I member 2 | 2.528286 | 31 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Nuclear hormone receptor subfamily 1 group I member 2 |
| NS3 | Genome polyprotein | 3.184704 | 303 | actual&Predicted | Hepacivirus C | virus | Serine protease S29 family |
| NS4A | Non-structural protein 4A | 3.050281 | 100 | actual&Predicted | Hepacivirus C | virus | Serine protease S29 regulatory subfamily |
| Ntsr1 | Neurotensin receptor type 1 | 2.612409 | 16 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Neurotensin receptor |
| NTSR2 | Neurotensin receptor type 2 | 2.558591 | 4 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Neurotensin receptor |
| O18323 | Voltage-dependent calcium channel alpha-1 subunit | 5.437578 | 3 | predicted | Blattella germanica (German cockroach) (Blatta germanica) | arthropoda | Voltage-gated calcium channel |
| OAT | Ornithine aminotransferase, mitochondrial | 2.198351 | 1 | predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Transferase |
| Oprd1 | Delta-type opioid receptor | 2.569792 | 426 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) - Sus scrofa (Pig) | mammals | Opioid receptor |
| Oprk1 | Kappa-type opioid receptor | 2.545269 | 405 | actual&Predicted | Cavia porcellus (Guinea pig) - Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Opioid receptor |
| Oprl1 | Nociceptin receptor | 3.109646 | 205 | actual&Predicted | Cavia porcellus (Guinea pig) - Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Opioid receptor |
| Oprm1 | Mu-type opioid receptor | 2.530672 | 629 | actual&Predicted | Bos taurus (Bovine) - Cavia porcellus (Guinea pig) - Homo sapiens (Human) - Macaca mulatta (Rhesus macaque) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Opioid receptor |
| OXTR | Oxytocin receptor | 2.548514 | 30 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Vasopressin and oxytocin receptor |
| PA | Polymerase acidic protein | 2.564255 | 10 | actual&Predicted | Influenza A virus (strain A/Hong Kong/1/1968 H3N2) - Influenza A virus (strain A/Puerto Rico/8/1934 H1N1) - Influenza A virus (strain A/Wilson-Smith/1933 H1N1) (Influenza A virus (strain A/WS/1933 H1N1)) - Influenza A virus (strain A/X-31 H3N2) - Influenza B virus (strain B/Lee/1940) | virus | Unclassified protein |
| Pam | Peptidyl-glycine alpha-amidating monooxygenase - Peptidylglycine alpha-amidating monooxygenase | 2.222633 | 1 | predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Enzyme |
| PAX8 | Paired box protein Pax-8 | 1.835305 | 25 | actual&Predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| PB1 | RNA-directed RNA polymerase catalytic subunit | 4.469373 | 10 | actual&Predicted | Influenza A virus (strain A/Puerto Rico/8/1934 H1N1) - Influenza A virus (strain A/Wilson-Smith/1933 H1N1) (Influenza A virus (strain A/WS/1933 H1N1)) | virus | Transferase, Unclassified protein |
| PCSK6 | Proprotein convertase subtilisin/kexin type 6 | 4.31783 | 61 | predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Serine protease S8B subfamily |
| PCSK9 | Proprotein convertase subtilisin/kexin type 9 | 2.832994 | 8 | actual&Predicted | Homo sapiens (Human) | mammals | Serine protease S8A subfamily |
| PDK1 | [Pyruvate dehydrogenase | 2.168547 | 38 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Atypical protein kinase PDHK subfamily |
| PDPK1 | 3-phosphoinositide-dependent protein kinase 1 | 2.161876 | 70 | actual&Predicted | Homo sapiens (Human) | mammals | AGC protein kinase PDK1 subfamily |
| PF3D7_1133400 | Apical membrane antigen 1 | 2.238344 | 1 | actual&Predicted | Plasmodium falciparum (isolate 3D7) | protozoan | Unclassified protein |
| PGA | Pepsin A | 3.190349 | 18 | actual&Predicted | Sus scrofa (Pig) | mammals | Aspartic protease A1A subfamily |
| PIN1 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | 2.23377 | 90 | actual&Predicted | Homo sapiens (Human) | mammals | Isomerase |
| PKMYT1 | Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase | 2.897481 | 13 | actual&Predicted | Homo sapiens (Human) | mammals | Other protein kinase WEE family |
| PLAT | Tissue-type plasminogen activator | 2.394642 | 8 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Serine protease S1A subfamily |
| PLAU | Urokinase-type plasminogen activator | 2.421193 | 28 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) - Sus scrofa (Pig) | mammals | Serine protease S1A subfamily |
| PLG | Plasminogen | 2.534024 | 43 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Serine protease S1A subfamily |
| PLK1 | Serine/threonine-protein kinase PLK1 | 2.361027 | 205 | actual&Predicted | Homo sapiens (Human) - Xenopus laevis (African clawed frog) | mammals | Other protein kinase PLK family |
| PLK2 | Serine/threonine-protein kinase PLK2 | 2.669875 | 44 | actual&Predicted | Homo sapiens (Human) | mammals | Other protein kinase PLK2 |
| PLM2 | Plasmepsin-2 | 2.956212 | 42 | actual&Predicted | Plasmodium falciparum | protozoan | Aspartic protease A1A subfamily |
| Pmp22 | Peripheral myelin protein 22 | 2.610618 | 136 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Unclassified protein |
| pol | Pol polyprotein | 3.1264 | 316 | actual&Predicted | Human immunodeficiency virus 1 | virus | Aspartic protease A2A subfamily |
| pol | Integrase | 2.321646 | 66 | actual&Predicted | Human immunodeficiency virus 1 | virus | Hydrolase |
| POLG | Genome polyprotein [Cleaved into: Capsid protein C - Genome polyprotein [Cleaved into: Core protein p21 - Genome polyprotein [Cleaved into: Core protein; Envelope glycoprotein E1; Envelope glycoprotein E2 - Genome polyprotein [Cleaved into: N-terminal protease - Genome polyprotein [Cleaved into: P1; Capsid protein VP0 - Genome polyprotein [Cleaved into: P3; Protein 3AB; P2; P1; Capsid protein VP0 - Genome polyprotein [Cleaved into: Peptide 2k; Capsid protein C | 3.309322 | 185 | actual&Predicted | Bovine viral diarrhea virus (strain CP7) (BVDV) (Mucosal disease virus) - Coxsackievirus B3 (strain Nancy) - Dengue virus type 2 (strain Puerto Rico/PR159-S1/1969) (DENV-2) - Dengue virus type 2 (strain Thailand/16681/1984) (DENV-2) - Hepatitis C virus genotype 1a (isolate 1) (HCV) - Hepatitis C virus genotype 1a (isolate H) (HCV) - Hepatitis C virus genotype 1b (isolate BK) (HCV) - Hepatitis C virus genotype 1b (isolate Con1) (HCV) - Hepatitis C virus genotype 1b (isolate Japanese) (HCV) - Hepatitis C virus genotype 1b (strain HC-J4) (HCV) - Hepatitis C virus genotype 3a (isolate NZL1) (HCV) - Hepatitis GB virus B (GBV-B) (GB virus B) - Human rhinovirus 16 (HRV-16) - Poliovirus type 1 (strain Mahoney) - West Nile virus (WNV) | virus | Cysteine protease C18 family, Cysteine protease C3A subfamily, Enzyme, Serine protease S29 family, Transferase |
| POLK | DNA polymerase kappa | 2.190928 | 95 | actual&Predicted | Homo sapiens (Human) | mammals | Enzyme |
| Ppia | Peptidyl-prolyl cis-trans isomerase A | 3.72193 | 76 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Isomerase |
| PRE7 | Proteasome subunit beta type-6 | 3.284624 | 18 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | widespread | Threonine protease T1A subfamily |
| Prep | Prolyl endopeptidase | 1.880098 | 6 | actual&Predicted | Bos taurus (Bovine) - Elizabethkingia meningoseptica (Chryseobacterium meningosepticum) - Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) - Sus scrofa (Pig) | widespread | Serine protease S9A subfamily |
| PRKAR2A | cAMP-dependent protein kinase type II-alpha regulatory subunit | 3.318954 | 13 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) | mammals | Protein kinase regulatory subunit |
| Prkcd | Protein kinase C delta type | 2.749074 | 123 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | AGC protein kinase PKC delta subfamily |
| Prss2 | Anionic trypsin - Anionic trypsin-2 - Trypsin-2 | 2.449594 | 39 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Serine protease S1A subfamily |
| PRSS3 | Trypsin-3 | 2.476699 | 42 | actual&Predicted | Homo sapiens (Human) | mammals | Serine protease S1A subfamily |
| PSEN1 | Presenilin-1 | 2.903684 | 228 | actual&Predicted | Homo sapiens (Human) | mammals | Presenilin ER Ca2+ leak channel family |
| PSEN2 | Presenilin-2 | 2.903985 | 218 | actual&Predicted | Homo sapiens (Human) | mammals | Presenilin ER Ca2+ leak channel family |
| PSENEN | Gamma-secretase subunit PEN-2 | 2.904093 | 218 | actual&Predicted | Homo sapiens (Human) | mammals | Enzyme |
| pslo | Large conductance calcium activated potassium channel pSlo spliceform 1-5A | 5.405428 | 3 | predicted | Periplaneta americana (American cockroach) (Blatta americana) | arthropoda | Unclassified protein |
| Psmb5 | Proteasome subunit beta type-5 | 3.228685 | 75 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | widespread | Threonine protease T1A subfamily |
| Pth1r | Parathyroid hormone/parathyroid hormone-related peptide receptor | 2.15591 | 60 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Parathyroid hormone receptor |
| PTPN1 | Tyrosine-protein phosphatase non-receptor type 1 | 2.461789 | 152 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Tyrosine protein phosphatase |
| Ptpn11 | Tyrosine-protein phosphatase non-receptor type 11 | 2.49952 | 25 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Tyrosine protein phosphatase |
| Q51816 | Arg-gingipain-1 proteinase | 4.725865 | 1 | predicted | Porphyromonas gingivalis | bacteria | Enzyme |
| Q76353 | Integrase | 2.187015 | 80 | actual&Predicted | Human immunodeficiency virus 1 | virus | Enzyme, Hydrolase |
| Q82323 | Protease | 4.491637 | 10 | predicted | Human T-cell leukemia virus type I | virus | Cysteine protease C3A subfamily |
| Q8WSF8 | Soluble acetylcholine receptor | 2.442141 | 3 | actual&Predicted | Aplysia californica (California sea hare) | mollusca | Nicotinic acetylcholine receptor |
| Q91H74 | Genome polyprotein | 2.468386 | 1 | predicted | Dengue virus 2 | virus | Cysteine protease C18 family, Cysteine protease C3A subfamily, Enzyme, Serine protease S29 family, Transferase |
| Q9N6S8 | Cysteine proteinase falcipain 2a | 2.63911 | 4 | actual&Predicted | Plasmodium falciparum | protozoan | Cysteine protease C1A family |
| RAMP1 | Receptor activity-modifying protein 1 | 3.215145 | 7 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Other membrane protein |
| RECQL | ATP-dependent DNA helicase Q1 | 2.411766 | 58 | actual&Predicted | Homo sapiens (Human) | mammals | Enzyme |
| REN | Renin | 2.923023 | 256 | actual&Predicted | Callithrix jacchus (White-tufted-ear marmoset) - Homo sapiens (Human) - Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) - Macaca mulatta (Rhesus macaque) - Rattus norvegicus (Rat) | mammals | Aspartic protease A1A subfamily |
| reverse | Reverse transcriptase | 2.768169 | 139 | actual&Predicted | Human immunodeficiency virus 1 | virus | Enzyme |
| RGS4 | Regulator of G-protein signaling 4 | 2.279574 | 77 | actual&Predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| rhodesain | Cysteine protease | 2.777698 | 12 | actual&Predicted | Trypanosoma brucei rhodesiense | protozoan | Cysteine protease C1A family |
| ROCK1 | Rho-associated protein kinase 1 | 2.092779 | 63 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | AGC protein kinase ROCK subfamily |
| RORC | Nuclear receptor ROR-gamma | 2.430667 | 486 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Nuclear hormone receptor subfamily 1 group F member 3 |
| RPA1 | Replication protein A 70 kDa DNA-binding subunit | 2.71542 | 12 | actual&Predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| Rrm1 | Ribonucleoside-diphosphate reductase large subunit - Ribonucleoside-diphosphate reductase subunit alpha | 2.691655 | 13 | actual&Predicted | Homo sapiens (Human) - Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1) - Mus musculus (Mouse) - Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | widespread | Enzyme, Oxidoreductase |
| Rrm2 | Ribonucleoside-diphosphate reductase subunit M2 | 2.730031 | 9 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Oxidoreductase |
| RRM2B | Ribonucleoside-diphosphate reductase subunit M2 B | 2.677102 | 8 | predicted | Homo sapiens (Human) | mammals | Enzyme |
| S100A10 | Protein S100-A10 | 2.101293 | 1 | actual&Predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| Scn10a | Sodium channel protein type 10 subunit alpha | 2.503088 | 15 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Voltage-gated sodium channel |
| Scn2a | Sodium channel protein type 2 subunit alpha | 2.83494 | 78 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Voltage-gated sodium channel |
| Scn3a | Sodium channel protein type 3 subunit alpha | 2.787236 | 42 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Voltage-gated sodium channel |
| Scn4a | Sodium channel protein type 4 subunit alpha | 3.665772 | 131 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Voltage-gated sodium channel |
| Scn5a | Sodium channel protein type 5 subunit alpha | 2.608624 | 46 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Voltage-gated sodium channel |
| Scn8a | Sodium channel protein type 8 subunit alpha | 2.924122 | 13 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Voltage-gated sodium channel |
| Scn9a | Sodium channel protein type 9 subunit alpha | 2.45491 | 235 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Voltage-gated sodium channel |
| Sdc4 | Syndecan-4 | 4.843163 | 6 | predicted | Mus musculus (Mouse) | mammals | Unclassified protein |
| SIRT4 | NAD-dependent protein lipoamidase sirtuin-4, mitochondrial | 4.090657 | 1 | predicted | Homo sapiens (Human) | mammals | HDAC class III |
| SIRT5 | NAD-dependent protein deacylase sirtuin-5, mitochondrial | 3.310304 | 60 | actual&Predicted | Homo sapiens (Human) | mammals | HDAC class III |
| Slc22a1 | Solute carrier family 22 member 1 | 2.798511 | 34 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | SLC22 family of organic cation and anion transporters |
| SLC40A1 | Solute carrier family 40 member 1 | 2.746804 | 36 | actual&Predicted | Homo sapiens (Human) | mammals | SLC40 iron transporter |
| Slc47a1 | Multidrug and toxin extrusion protein 1 | 3.20394 | 13 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | SLC47 family of multidrug and toxin extrusion transporters |
| SLC47A2 | Multidrug and toxin extrusion protein 2 | 3.946571 | 9 | actual&Predicted | Homo sapiens (Human) | mammals | SLC47 family of multidrug and toxin extrusion transporters |
| Slc6a2 | Sodium-dependent noradrenaline transporter | 2.893414 | 319 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | SLC06 neurotransmitter transporter family |
| SLCO1A2 | Solute carrier organic anion transporter family member 1A2 | 2.891157 | 9 | actual&Predicted | Homo sapiens (Human) | mammals | SLC21/SLCO family of organic anion transporting polypeptides |
| SLCO1B1 | Solute carrier organic anion transporter family member 1B1 | 2.63446 | 212 | actual&Predicted | Homo sapiens (Human) | mammals | SLC21/SLCO family of organic anion transporting polypeptides |
| SLCO1B3 | Solute carrier organic anion transporter family member 1B3 | 2.592582 | 198 | actual&Predicted | Homo sapiens (Human) | mammals | SLC21/SLCO family of organic anion transporting polypeptides |
| SMAD3 | Mothers against decapentaplegic homolog 3 | 2.070766 | 237 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Unclassified protein |
| SRC | Neuronal proto-oncogene tyrosine-protein kinase Src - Proto-oncogene tyrosine-protein kinase Src | 2.624883 | 329 | actual&Predicted | Gallus gallus (Chicken) - Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Tyrosine protein kinase Src family |
| srtA | Class A sortase SrtA | 2.321665 | 8 | actual&Predicted | Staphylococcus aureus | bacteria | Cysteine protease |
| Sstr1 | Somatostatin receptor type 1 | 3.283043 | 36 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Somatostatin receptor |
| Sstr2 | Somatostatin receptor type 2 | 3.252076 | 47 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Somatostatin receptor |
| Sstr3 | Somatostatin receptor type 3 | 3.163586 | 29 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Somatostatin receptor |
| Sstr4 | Somatostatin receptor type 4 | 3.318165 | 33 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Somatostatin receptor |
| Sstr5 | Somatostatin receptor type 5 | 3.081178 | 39 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Somatostatin receptor |
| St14 | Suppressor of tumorigenicity 14 protein - Suppressor of tumorigenicity 14 protein homolog | 2.316456 | 14 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Serine protease S1A subfamily |
| SYK | Tyrosine-protein kinase SYK | 2.403357 | 170 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Tyrosine protein kinase Syk family |
| Tacr1 | Substance-P receptor | 3.447987 | 650 | actual&Predicted | Cavia porcellus (Guinea pig) - Homo sapiens (Human) - Meriones unguiculatus (Mongolian jird) (Mongolian gerbil) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Neurokinin receptor |
| TACR2 | Substance-K receptor | 3.076857 | 208 | actual&Predicted | Bos taurus (Bovine) - Cavia porcellus (Guinea pig) - Homo sapiens (Human) - Mesocricetus auratus (Golden hamster) - Mus musculus (Mouse) - Oryctolagus cuniculus (Rabbit) - Rattus norvegicus (Rat) | mammals | Neurokinin receptor, Unclassified protein |
| Tacr3 | Neuromedin-K receptor | 2.82526 | 74 | actual&Predicted | Cavia porcellus (Guinea pig) - Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Neurokinin receptor |
| TBXAS1 | Thromboxane-A synthase | 2.272156 | 36 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Cytochrome P450 5A1 |
| TDP1 | Tyrosyl-DNA phosphodiesterase 1 | 2.0542 | 803 | actual&Predicted | Homo sapiens (Human) | mammals | Phosphodiesterase |
| TEAD1 | Transcriptional enhancer factor TEF-1 | 4.587975 | 10 | predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| TERF2IP | Telomeric repeat-binding factor 2-interacting protein 1 | 5.030347 | 21 | predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| TFPI | Tissue factor pathway inhibitor | 4.720938 | 607 | predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| thyA | Thymidylate synthase - Thymidylate synthase ThyA | 2.170417 | 11 | actual&Predicted | Bos taurus (Bovine) - Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) - Cryptococcus neoformans var. neoformans serotype D (strain B-3501A) (Filobasidiella neoformans) - Enterococcus faecalis (strain ATCC 700802 / V583) - Escherichia coli (strain K12) - Homo sapiens (Human) - Lactobacillus casei - Mus musculus (Mouse) - Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) - Pneumocystis carinii - Rattus norvegicus (Rat) | widespread | Transferase |
| TLR1 | Toll-like receptor 1 | 3.698684 | 10 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Unclassified protein |
| TLR2 | Toll-like receptor 2 | 3.070977 | 44 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Toll-like and Il-1 receptors |
| TMPRSS6 | Transmembrane protease serine 6 | 2.799659 | 10 | predicted | Homo sapiens (Human) | mammals | Serine protease |
| TNF | Tumor necrosis factor | 2.258399 | 22 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Secreted protein |
| TNFSF11 | Tumor necrosis factor ligand superfamily member 11 | 2.378815 | 1 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Secreted protein |
| Tp53 | Cellular tumor antigen p53 | 1.983193 | 243 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Transcription factor |
| TRPA1 | Transient receptor potential cation channel subfamily A member 1 | 2.134334 | 18 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Transient receptor potential channel |
| TRPM8 | Transient receptor potential cation channel subfamily M member 8 | 2.543315 | 18 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Transient receptor potential channel |
| trxr-2 | Probable glutathione reductase 2 - Thioredoxin reductase 2 - Thioredoxin reductase 2, mitochondrial | 3.17019 | 5 | actual&Predicted | Caenorhabditis elegans - Homo sapiens (Human) - Plasmodium falciparum (isolate 3D7) - Rattus norvegicus (Rat) | mammals | Enzyme, Oxidoreductase |
| TRY1 | Anionic trypsin-1 - Cationic trypsin - Trypsin-1 | 2.465278 | 100 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Hydrolase, Serine protease S1A subfamily |
| Tyr | Tyrosinase | 2.101828 | 9 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Oxidoreductase |
| Uts2r | Urotensin-2 receptor | 3.086523 | 78 | actual&Predicted | Homo sapiens (Human) - Macaca mulatta (Rhesus macaque) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Neuropeptide receptor |
| VDR | Vitamin D3 receptor | 2.480289 | 115 | actual&Predicted | Bos taurus (Bovine) - Gallus gallus (Chicken) - Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) - Sus scrofa (Pig) | mammals | Nuclear hormone receptor subfamily 1 group I member 1 |
| Vipr1 | Vasoactive intestinal polypeptide receptor 1 | 2.709173 | 4 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Vasoactive intestinal peptide receptor |
| VIPR2 | Vasoactive intestinal polypeptide receptor 2 | 3.286707 | 9 | actual&Predicted | Homo sapiens (Human) | mammals | Vasoactive intestinal peptide receptor |
| VWF | von Willebrand factor | 5.648729 | 6 | predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| WDR5 | WD repeat-containing protein 5 | 2.459145 | 21 | actual&Predicted | Homo sapiens (Human) | mammals | Other nuclear protein |
| WEE1 | Wee1-like protein kinase | 2.129928 | 25 | actual&Predicted | Homo sapiens (Human) | mammals | Other protein kinase WEE family |
| XIAP | E3 ubiquitin-protein ligase XIAP | 2.604257 | 131 | actual&Predicted | Homo sapiens (Human) | mammals | Other cytosolic protein |
| YAP1 | Transcriptional coactivator YAP1 | 4.593816 | 9 | predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| YWHAB | 14-3-3 protein beta/alpha | 4.521477 | 1 | predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| YWHAH | 14-3-3 protein eta | 4.232089 | 1 | predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| YWHAQ | 14-3-3 protein theta | 4.232089 | 1 | predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| ZAP70 | Tyrosine-protein kinase ZAP-70 | 2.526223 | 42 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Tyrosine protein kinase Syk family |
