We can review here where the TRP channels molecules predicted as SARS active hit attending to their clusterID. Graphs summarize molecule-protein interactions for the TRP channels module obtained by interactions-based segmentation. ChEMBL molecule registry number (molregnos) labels have been removed in the networks to facilitate visualization of interactions. Only known drugs and protein names remain.
It can be appreciated how main molecular clusters interact specifically with different TRP channel proteins.
In this tab, we show interactions of most TRP specific clusters. Lack of specificity is restricted to few compounds. TRPV1 gathers most of the molecular clusters, while TRPV4 and TRPM8 interact specifically with ClID_2342 and ClID_7049 respectively.
See compound structures of most TRP specific clusters
In this tab, we can review where the TRP channel molecules hit attending to their clusterID. Graphs summarize molecule-protein interactions for the Na channels module obtained by interactions-based segmentation. ChEMBL molecule registry number (molregnos) labels have been removed in the networks to facilitate visualization of interactions. Only known drugs and protein names remain.
Let’s examine the structures of the rest of TRP channel clusters.
