| ABCB1 | ATP-dependent translocase ABCB1 - Multidrug resistance protein 1 | 3.132702 | 284 | actual&Predicted | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) - Homo sapiens (Human) - Rattus norvegicus (Rat) | widespread | ABCB subfamily |
| Abcb11 | Bile salt export pump | 3.236667 | 57 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | ABCB subfamily |
| Abcb1a | ATP-dependent translocase ABCB1 | 3.118092 | 13 | actual&Predicted | Mus musculus (Mouse) | mammals | ABCB subfamily |
| Abcb1b | ATP-dependent translocase ABCB1 | 3.388412 | 15 | actual&Predicted | Mus musculus (Mouse) | mammals | ABCB subfamily |
| Abcc2 | Canalicular multispecific organic anion transporter 1 | 2.843115 | 50 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | ABCC subfamily |
| ADRA1A | Alpha-1A adrenergic receptor | 2.560372 | 418 | actual&Predicted | Bos taurus (Bovine) - Cavia porcellus (Guinea pig) - Homo sapiens (Human) - Mus musculus (Mouse) - Oryctolagus cuniculus (Rabbit) - Rattus norvegicus (Rat) | mammals | Adrenergic receptor |
| Adra1b | Alpha-1B adrenergic receptor | 2.578805 | 380 | actual&Predicted | Homo sapiens (Human) - Mesocricetus auratus (Golden hamster) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Adrenergic receptor |
| ADRA2A | Alpha-2A adrenergic receptor | 2.377715 | 160 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) - Sus scrofa (Pig) | mammals | Adrenergic receptor |
| ADRA2B | Alpha-2B adrenergic receptor | 2.377486 | 140 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Adrenergic receptor |
| ALOX15 | Arachidonate 15-lipoxygenase - Probable linoleate 9S-lipoxygenase 5 | 2.217103 | 111 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Oryctolagus cuniculus (Rabbit) - Rattus norvegicus (Rat) - Solanum tuberosum (Potato) - Sus scrofa (Pig) | widespread | Oxidoreductase |
| ALOX15B | Arachidonate 15-lipoxygenase B | 2.376985 | 141 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Oxidoreductase |
| APP | Amyloid-beta A4 protein - Amyloid-beta precursor protein | 2.485581 | 104 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Membrane receptor |
| ATAD5 | ATPase family AAA domain-containing protein 5 | 2.348577 | 323 | actual&Predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| ATXN2 | Ataxin-2 | 2.123454 | 211 | actual&Predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| BAZ2B | Bromodomain adjacent to zinc finger domain protein 2B | 2.209027 | 71 | actual&Predicted | Homo sapiens (Human) | mammals | Bromodomain, Plant homeodomain |
| BLM | Bloom syndrome protein | 2.358842 | 97 | actual&Predicted | Homo sapiens (Human) | mammals | Enzyme |
| CACNA1C | Voltage-dependent L-type calcium channel subunit alpha-1C | 3.191334 | 135 | actual&Predicted | Cavia porcellus (Guinea pig) - Homo sapiens (Human) - Mus musculus (Mouse) - Oryctolagus cuniculus (Rabbit) - Rattus norvegicus (Rat) | mammals | Voltage-gated calcium channel |
| camC | Camphor 5-monooxygenase | 2.140222 | 1 | actual&Predicted | Pseudomonas putida (Arthrobacter siderocapsulatus) | bacteria | Cytochrome P450 CAM family |
| CBFB | Core-binding factor subunit beta | 2.366161 | 66 | actual&Predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| Chrm1 | Muscarinic acetylcholine receptor DM1 - Muscarinic acetylcholine receptor M1 | 2.026578 | 302 | actual&Predicted | Drosophila melanogaster (Fruit fly) - Homo sapiens (Human) - Macaca mulatta (Rhesus macaque) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Acetylcholine receptor |
| CHRM2 | Muscarinic acetylcholine receptor M2 | 2.040694 | 174 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) - Sus scrofa (Pig) | mammals | Acetylcholine receptor |
| CYP11A1 | Cholesterol side-chain cleavage enzyme, mitochondrial | 2.870501 | 5 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Cytochrome P450 11A1 |
| CYP11B1 | Cytochrome P450 11B1, mitochondrial | 1.878708 | 22 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Cytochrome P450 11B1 |
| Cyp11b2 | Cytochrome P450 11B2, mitochondrial | 1.80175 | 11 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Cytochrome P450 11B2 |
| CYP17A1 | Steroid 17-alpha-hydroxylase/17,20 lyase | 2.37146 | 41 | actual&Predicted | Homo sapiens (Human) - Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) - Rattus norvegicus (Rat) | mammals | Cytochrome P450 17A1, Cytochrome P450 family 26 |
| CYP19A1 | Aromatase | 2.055777 | 53 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Cytochrome P450 19A1 |
| Cyp1a2 | Cytochrome P450 1A2 | 2.108485 | 194 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Cytochrome P450 1A1, Cytochrome P450 1A2 |
| CYP21A2 | Steroid 21-hydroxylase | 2.953778 | 20 | actual&Predicted | Homo sapiens (Human) | mammals | Cytochrome P450 21A2 |
| CYP24A1 | 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial | 3.577649 | 10 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Cytochrome P450 24A1 |
| CYP27B1 | 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial | 3.877469 | 4 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Cytochrome P450 27B1 |
| Cyp2a2 | Cytochrome P450 2A2 | 4.615632 | 1 | actual&Predicted | Rattus norvegicus (Rat) | mammals | Cytochrome P450 2A2 |
| CYP2B6 | Cytochrome P450 2B6 | 2.531639 | 16 | actual&Predicted | Homo sapiens (Human) | mammals | Cytochrome P450 2B6 |
| CYP2C19 | Cytochrome P450 2C19 | 2.172638 | 199 | actual&Predicted | Homo sapiens (Human) | mammals | Cytochrome P450 2C19 |
| CYP2C8 | Cytochrome P450 2C8 | 2.616667 | 21 | actual&Predicted | Homo sapiens (Human) | mammals | Cytochrome P450 2C8 |
| CYP2C9 | Cytochrome P450 2C9 | 2.239767 | 228 | actual&Predicted | Homo sapiens (Human) | mammals | Cytochrome P450 2C9 |
| CYP2D6 | Cytochrome P450 2D6 | 2.197044 | 290 | actual&Predicted | Homo sapiens (Human) | mammals | Cytochrome P450 2D6 |
| CYP3A4 | Cytochrome P450 3A4 | 2.11263 | 423 | actual&Predicted | Homo sapiens (Human) | mammals | Cytochrome P450 3A4 |
| CYP3A5 | Cytochrome P450 3A5 | 2.731379 | 11 | actual&Predicted | Homo sapiens (Human) | mammals | Cytochrome P450 3A5 |
| CYP4F2 | Cytochrome P450 4F2 | 3.329077 | 1 | actual&Predicted | Homo sapiens (Human) | mammals | Cytochrome P450 4F2 |
| CYP51A1 | Lanosterol 14-alpha demethylase | 3.46786 | 5 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Cytochrome P450 51A1 |
| Cyp7a1 | Cytochrome P450 7A1 | 3.671108 | 1 | actual&Predicted | Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Cytochrome P450 7A1 |
| Drd1 | D(1) dopamine receptor - D(1A) dopamine receptor | 2.513053 | 256 | actual&Predicted | Bos taurus (Bovine) - Carassius auratus (Goldfish) - Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) - Sus scrofa (Pig) | mammals | Dopamine receptor |
| EHMT2 | Histone-lysine N-methyltransferase EHMT2 | 2.21372 | 321 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Protein methyltransferase |
| ERG6 | Sterol 24-C-methyltransferase | 3.437967 | 1 | actual&Predicted | Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica) | fungi | Transferase |
| FEN1 | Flap endonuclease 1 | 2.181775 | 62 | actual&Predicted | Homo sapiens (Human) | mammals | Hydrolase |
| Fshr | Follicle-stimulating hormone receptor | 3.141737 | 12 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Glycohormone receptor |
| Glp1r | Glucagon-like peptide 1 receptor | 2.213005 | 545 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Glucagon-like peptide receptor |
| GMNN | Geminin | 2.299658 | 517 | actual&Predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| GNRHR | Gonadotropin-releasing hormone receptor | 3.415856 | 313 | actual&Predicted | Homo sapiens (Human) - Macaca mulatta (Rhesus macaque) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | GnRH receptor |
| HIF1A | Hypoxia-inducible factor 1-alpha | 2.199057 | 125 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Transcription factor |
| HRH2 | Histamine H2 receptor | 2.283425 | 38 | actual&Predicted | Cavia porcellus (Guinea pig) - Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Histamine receptor |
| HSP90AA1 | Heat shock protein HSP 90-alpha | 2.998097 | 330 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Other cytosolic protein |
| HTR1B | 5-hydroxytryptamine receptor 1B | 2.323802 | 119 | actual&Predicted | Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) - Gorilla gorilla gorilla (Western lowland gorilla) - Homo sapiens (Human) - Mus musculus (Mouse) - Oryctolagus cuniculus (Rabbit) - Rattus norvegicus (Rat) - Sus scrofa (Pig) | mammals | Serotonin receptor |
| Htr2b | 5-hydroxytryptamine receptor 2B | 2.498956 | 238 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Serotonin receptor |
| IDO1 | Indoleamine 2,3-dioxygenase 1 | 1.906322 | 18 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Oxidoreductase |
| KCNH2 | Potassium voltage-gated channel subfamily H member 2 | 2.621166 | 505 | actual&Predicted | Canis lupus familiaris (Dog) (Canis familiaris) - Cavia porcellus (Guinea pig) - Homo sapiens (Human) - Oryctolagus cuniculus (Rabbit) | mammals | Voltage-gated potassium channel |
| Kcnma1 | Calcium-activated potassium channel subunit alpha-1 | 2.3864 | 7 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Calcium-activated potassium channel |
| KCNMB1 | Calcium-activated potassium channel subunit beta-1 | 3.085782 | 2 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) | mammals | Calcium-activated potassium channel auxiliary subunit slowpoke-beta family |
| Kmt2a | Histone-lysine N-methyltransferase 2A | 2.389978 | 290 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Bromodomain, Plant homeodomain, Protein methyltransferase |
| Lhcgr | Lutropin-choriogonadotropic hormone receptor | 2.753814 | 7 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Glycohormone receptor |
| LMNA | Prelamin-A/C [Cleaved into: Lamin-A/C | 2.299744 | 286 | actual&Predicted | Homo sapiens (Human) | mammals | Other nuclear protein, Structural protein |
| MAPK1 | Mitogen-activated protein kinase 1 | 2.347294 | 291 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | CMGC protein kinase ERK subfamily, CMGC protein kinase ERK1 |
| MAPT | Microtubule-associated protein tau | 2.167214 | 304 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Other cytosolic protein |
| MEN1 | Menin | 2.394322 | 272 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Unclassified protein |
| Nfe2l2 | Nuclear factor erythroid 2-related factor 2 | 2.210433 | 331 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Unclassified protein |
| NFKB1 | Nuclear factor NF-kappa-B p105 subunit | 2.314825 | 68 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Other cytosolic protein, Transcription factor |
| Npsr1 | Neuropeptide S receptor | 2.431556 | 108 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Neuropeptide receptor |
| NR1I2 | Nuclear receptor subfamily 1 group I member 2 | 2.528286 | 31 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Nuclear hormone receptor subfamily 1 group I member 2 |
| NS1 | Non-structural protein 1 | 2.403943 | 164 | actual&Predicted | Influenza A virus (A/WSN/1933(H1N1)) | virus | Unclassified protein |
| Oprd1 | Delta-type opioid receptor | 2.569792 | 426 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) - Sus scrofa (Pig) | mammals | Opioid receptor |
| Oprk1 | Kappa-type opioid receptor | 2.545269 | 405 | actual&Predicted | Cavia porcellus (Guinea pig) - Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Opioid receptor |
| Oprm1 | Mu-type opioid receptor | 2.530672 | 629 | actual&Predicted | Bos taurus (Bovine) - Cavia porcellus (Guinea pig) - Homo sapiens (Human) - Macaca mulatta (Rhesus macaque) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Opioid receptor |
| PF3D7_1443900 | Heat shock protein 90, putative | 2.390273 | 29 | actual&Predicted | Plasmodium falciparum (isolate 3D7) | protozoan | Unclassified protein |
| RORC | Nuclear receptor ROR-gamma | 2.430667 | 486 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Nuclear hormone receptor subfamily 1 group F member 3 |
| RUNX1 | Runt-related transcription factor 1 | 2.370204 | 66 | actual&Predicted | Homo sapiens (Human) | mammals | Transcription factor |
| RXRA | Retinoic acid receptor RXR-alpha | 2.483413 | 67 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Nuclear hormone receptor subfamily 2 group B member 1 |
| Slc22a1 | Solute carrier family 22 member 1 | 2.798511 | 34 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | SLC22 family of organic cation and anion transporters |
| Slc6a2 | Sodium-dependent noradrenaline transporter | 2.893414 | 319 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | SLC06 neurotransmitter transporter family |
| Slc6a3 | Sodium-dependent dopamine transporter | 3.088051 | 754 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | SLC06 neurotransmitter transporter family |
| SLC6A4 | Sodium-dependent serotonin transporter | 3.162982 | 1182 | actual&Predicted | Homo sapiens (Human) - Macaca mulatta (Rhesus macaque) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | SLC06 neurotransmitter transporter family |
| SLCO1A2 | Solute carrier organic anion transporter family member 1A2 | 2.891157 | 9 | actual&Predicted | Homo sapiens (Human) | mammals | SLC21/SLCO family of organic anion transporting polypeptides |
| SLCO1B1 | Solute carrier organic anion transporter family member 1B1 | 2.63446 | 212 | actual&Predicted | Homo sapiens (Human) | mammals | SLC21/SLCO family of organic anion transporting polypeptides |
| SLCO1B3 | Solute carrier organic anion transporter family member 1B3 | 2.592582 | 198 | actual&Predicted | Homo sapiens (Human) | mammals | SLC21/SLCO family of organic anion transporting polypeptides |
| SLCO2B1 | Solute carrier organic anion transporter family member 2B1 | 2.957937 | 24 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | SLC21/SLCO family of organic anion transporting polypeptides |
| SMAD3 | Mothers against decapentaplegic homolog 3 | 2.070766 | 237 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Unclassified protein |
| SMN1 | Survival motor neuron protein | 2.345972 | 219 | actual&Predicted | Homo sapiens (Human) | mammals | Tudor domain |
| SNCA | Alpha-synuclein | 2.192041 | 86 | actual&Predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| TACR2 | Substance-K receptor | 3.076857 | 208 | actual&Predicted | Bos taurus (Bovine) - Cavia porcellus (Guinea pig) - Homo sapiens (Human) - Mesocricetus auratus (Golden hamster) - Mus musculus (Mouse) - Oryctolagus cuniculus (Rabbit) - Rattus norvegicus (Rat) | mammals | Neurokinin receptor, Unclassified protein |
| TARDBP | TAR DNA-binding protein 43 | 2.15341 | 136 | actual&Predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| TBXAS1 | Thromboxane-A synthase | 2.272156 | 36 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Cytochrome P450 5A1 |
| TDP1 | Tyrosyl-DNA phosphodiesterase 1 | 2.0542 | 803 | actual&Predicted | Homo sapiens (Human) | mammals | Phosphodiesterase |
| THPO | Thrombopoietin | 2.323573 | 53 | actual&Predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| TSHR | Thyrotropin receptor | 2.179486 | 114 | actual&Predicted | Homo sapiens (Human) | mammals | Glycohormone receptor |
| Txnrd1 | Thioredoxin reductase 1, cytoplasmic | 2.267945 | 155 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Oxidoreductase |
| UGT1A1 | UDP-glucuronosyltransferase 1-1 | 3.44996 | 6 | actual&Predicted | Homo sapiens (Human) | mammals | Transferase |
| USP2 | Ubiquitin carboxyl-terminal hydrolase 2 | 2.165701 | 113 | actual&Predicted | Homo sapiens (Human) | mammals | Cysteine protease C19 family |
