ABC-family proteins mediated transport | 5.415877231 | 5.104896941 | 0.466020424 | 94664 | 31 | pathways | 11 | 0.212247515 | 0.243326554 | 2188.260824 | 37 | 0.001511109 |
Activation of BIM and translocation to mitochondria | 5.23872694 | 4.44851573 | 0.468111101 | 3896 | 3 | pathways | 13 | 0.143819248 | 0.155561349 | 0 | 33 | 6.14E-04 |
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon | 4.495833641 | 4.429748946 | 0.400343387 | 6260 | 8 | pathways | 13 | 0.154420341 | 0.173032238 | 5232 | 38 | 0.001119043 |
Activation of NF-kappaB in B cells | 5.477461049 | 5.12198341 | 0.471300296 | 126468 | 26 | pathways | 11 | 0.214447684 | 0.246041991 | 624.6671105 | 37 | 9.59E-04 |
Activation of PPARGC1A (PGC-1alpha) by phosphorylation | 5.141204125 | 4.650460623 | 0.469517218 | 46805 | 16 | pathways | 11 | 0.181121751 | 0.20383943 | 1718.67761 | 21 | 0.001512611 |
Acyl chain remodeling of DAG and TAG | 5.365328833 | 4.757996686 | 0.447879075 | 2437 | 3 | pathways | 13 | 0.163577959 | 0.178314452 | 330 | 1 | 0.001058903 |
Acyl chain remodelling of PS | 5.757429024 | 4.668415983 | 0.403429239 | 2810 | 10 | pathways | 15 | 0.129880322 | 0.141290905 | 0.5 | 13 | 9.86E-04 |
alpha-linolenic acid (ALA) metabolism | 4.501740148 | 4.816240841 | 0.511675748 | 624 | 8 | pathways | 15 | 0.094937617 | 0.104656534 | 662 | 8 | 0.001828398 |
AMPK inhibits chREBP transcriptional activation activity | 5.117184488 | 4.710858141 | 0.545685347 | 18809 | 10 | pathways | 11 | 0.166373461 | 0.184884124 | 0.75 | 21 | 9.78E-04 |
Anchoring of the basal body to the plasma membrane | 4.886944287 | 4.738234298 | 0.435878203 | 221566 | 22 | pathways | 9 | 0.223422207 | 0.258344723 | 1467.388961 | 24 | 0.001131882 |
Antigen processing: Ubiquitination & Proteasome degradation | 5.365368423 | 5.200492755 | 0.49242015 | 82659 | 27 | pathways | 11 | 0.211704509 | 0.241186574 | 662.487438 | 37 | 0.001087151 |
APC/C:Cdc20 mediated degradation of Cyclin B | 5.390304905 | 4.63353775 | 0.402248115 | 13697 | 6 | pathways | 11 | 0.20152207 | 0.230692281 | 1.33840668 | 24 | 5.68E-04 |
APC/C:Cdc20 mediated degradation of Securin | 5.610251149 | 5.570576799 | 0.58219255 | 79596 | 11 | pathways | 11 | 0.211569191 | 0.240179525 | 1.487437988 | 37 | 6.57E-04 |
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | 5.638325132 | 5.490138975 | 0.565447287 | 116560 | 15 | pathways | 11 | 0.216269193 | 0.247376331 | 390.0913506 | 37 | 8.60E-04 |
ARL13B-mediated ciliary trafficking of INPP5E | 5.013302245 | 4.886256056 | 0.435927489 | 1483 | 3 | pathways | 15 | 0.130186824 | 0.140754303 | 661 | 37 | 0.001366043 |
Aryl hydrocarbon receptor signalling | 4.612336678 | 4.919360379 | 0.429495668 | 5846 | 6 | pathways | 11 | 0.180824911 | 0.198898295 | 0 | 1 | 5.34E-04 |
Asymmetric localization of PCP proteins | 5.562956258 | 5.499476847 | 0.561651931 | 79620 | 13 | pathways | 11 | 0.211569191 | 0.240179525 | 1.487437988 | 37 | 6.57E-04 |
AUF1 (hnRNP D0) binds and destabilizes mRNA | 5.509874364 | 5.434135079 | 0.546816799 | 84067 | 15 | pathways | 11 | 0.211569191 | 0.240179525 | 1.487437988 | 37 | 6.57E-04 |
AURKA Activation by TPX2 | 4.951487111 | 4.752117992 | 0.443463148 | 226620 | 22 | pathways | 9 | 0.223422207 | 0.258344723 | 1467.388961 | 24 | 0.001131882 |
Autodegradation of Cdh1 by Cdh1:APC/C | 5.603872601 | 5.55581074 | 0.578206334 | 75378 | 11 | pathways | 11 | 0.211569191 | 0.240179525 | 1.487437988 | 37 | 6.57E-04 |
Autodegradation of the E3 ubiquitin ligase COP1 | 5.517602998 | 5.453207182 | 0.541475095 | 132379 | 16 | pathways | 11 | 0.211569191 | 0.240179525 | 1.487437988 | 37 | 6.57E-04 |
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members | 5.844413247 | 4.892633381 | 0.473174984 | 3264 | 5 | pathways | 13 | 0.164227239 | 0.180806299 | 225.345869 | 33 | 9.61E-04 |
Calcitonin-like ligand receptors | 6.031244049 | 4.941595417 | 0.671766717 | 3871 | 11 | pathways | 15 | 0.119775647 | 0.134001384 | 7.5 | 32 | 0.002516624 |
Carboxyterminal post-translational modifications of tubulin | 5.377071842 | 5.676146092 | 0.692004864 | 945566 | 5 | pathways | 11 | 0.185486131 | 0.213739085 | 4.811335117 | 29 | 8.82E-04 |
Cdc20:Phospho-APC/C mediated degradation of Cyclin A | 5.620954869 | 5.443728527 | 0.567726225 | 99960 | 20 | pathways | 11 | 0.226789997 | 0.269139387 | 1113.081153 | 24 | 0.001209662 |
CDK-mediated phosphorylation and removal of Cdc6 | 5.548570685 | 5.485924721 | 0.5613308 | 95730 | 19 | pathways | 9 | 0.226634714 | 0.261720136 | 1135.539508 | 24 | 0.001023884 |
CDT1 association with the CDC6:ORC:origin complex | 5.527443232 | 5.525709443 | 0.562299534 | 207606 | 13 | pathways | 11 | 0.211569191 | 0.240179525 | 1.487437988 | 37 | 6.57E-04 |
Cilium Assembly | 5.429886588 | 5.593970834 | 0.670211884 | 515610 | 6 | pathways | 11 | 0.185486131 | 0.213739085 | 4.811335117 | 29 | 8.82E-04 |
Clathrin derived vesicle budding | 5.3025 | 5.121329683 | 0.75 | 4 | 1 | pathways | 13 | 0.161660562 | 0.178256306 | 0 | 29 | 5.11E-04 |
CLEC7A (Dectin-1) signaling | 5.37420548 | 5.072341255 | 0.473746581 | 129242 | 32 | pathways | 11 | 0.214447684 | 0.246041991 | 624.6671105 | 37 | 9.59E-04 |
Coenzyme A biosynthesis | 5.780705279 | 5.24550675 | 0.727248885 | 73 | 3 | pathways | 1 | 1 | 1 | 1 | 0 | 0.001922529 |
COPI-dependent Golgi-to-ER retrograde traffic | 4.382620548 | 5.126260181 | 0.512096536 | 476618 | 25 | pathways | 11 | 0.197435133 | 0.232425245 | 2689.830311 | 29 | 0.002110593 |
COPI-independent Golgi-to-ER retrograde traffic | 5.084104327 | 5.42479566 | 0.590517225 | 473552 | 8 | pathways | 11 | 0.185486131 | 0.213739085 | 4.811335117 | 29 | 8.82E-04 |
COPI-mediated anterograde transport | 5.080759835 | 5.403694595 | 0.600120383 | 472871 | 9 | pathways | 11 | 0.196380896 | 0.226936826 | 1171.225188 | 29 | 0.001195193 |
Costimulation by the CD28 family | 6.097700971 | 4.930425273 | 0.514683308 | 23428 | 8 | pathways | 13 | 0.190723135 | 0.220114792 | 0.109219858 | 14 | 7.79E-04 |
Cross-presentation of soluble exogenous antigens (endosomes) | 5.415246812 | 5.325767097 | 0.527768783 | 79666 | 14 | pathways | 11 | 0.211569191 | 0.240179525 | 1.487437988 | 37 | 6.57E-04 |
Cyclin A/B1/B2 associated events during G2/M transition | 5.544394229 | 4.740132605 | 0.405937962 | 98880 | 27 | pathways | 9 | 0.207198748 | 0.241374742 | 218.1074274 | 24 | 0.001134664 |
Cyclin A:Cdk2-associated events at S phase entry | 5.385534008 | 4.818644342 | 0.414364723 | 33093 | 24 | pathways | 9 | 0.223120998 | 0.262952573 | 2184.702305 | 24 | 0.001620863 |
Dectin-1 mediated noncanonical NF-kB signaling | 5.51427866 | 5.346851134 | 0.531177397 | 99746 | 18 | pathways | 11 | 0.211569191 | 0.240179525 | 1.487437988 | 37 | 6.57E-04 |
Defective CFTR causes cystic fibrosis | 5.582601828 | 5.512759002 | 0.565912654 | 80686 | 13 | pathways | 11 | 0.211569191 | 0.240179525 | 1.487437988 | 37 | 6.57E-04 |
Defective LFNG causes SCDO3 | 8.122146213 | 4.975438918 | 0.7575 | 47 | 4 | pathways | 13 | 0.138118089 | 0.147603261 | 0 | 41 | 6.63E-04 |
Degradation of AXIN | 5.643520842 | 5.35746271 | 0.523750664 | 80420 | 17 | pathways | 11 | 0.211569191 | 0.240179525 | 1.487437988 | 37 | 6.57E-04 |
Degradation of beta-catenin by the destruction complex | 5.544679313 | 5.247425147 | 0.504027541 | 89252 | 22 | pathways | 11 | 0.211569191 | 0.240179525 | 1.487437988 | 37 | 6.57E-04 |
Degradation of DVL | 5.531561769 | 5.476305323 | 0.551149886 | 79640 | 14 | pathways | 11 | 0.211569191 | 0.240179525 | 1.487437988 | 37 | 6.57E-04 |
Degradation of GLI1 by the proteasome | 5.448529095 | 5.338798374 | 0.526799038 | 89908 | 17 | pathways | 11 | 0.218987761 | 0.251792962 | 890.5519021 | 37 | 9.55E-04 |
Degradation of GLI2 by the proteasome | 5.429184071 | 5.287806434 | 0.516629307 | 98223 | 22 | pathways | 11 | 0.218987761 | 0.251792962 | 890.5519021 | 37 | 9.55E-04 |
Deposition of new CENPA-containing nucleosomes at the centromere | 5.605515085 | 5.029272555 | 0.578510896 | 271 | 6 | pathways | 10 | 0.181918109 | 0.203918501 | 2634.669507 | 41 | 0.001088806 |
Downstream TCR signaling | 5.571327859 | 5.063366056 | 0.478006909 | 156653 | 42 | pathways | 11 | 0.2335097 | 0.27631821 | 14830.34493 | 14 | 0.001540139 |
E2F-enabled inhibition of pre-replication complex formation | 5.390304905 | 4.63353775 | 0.402248115 | 13697 | 6 | pathways | 11 | 0.20152207 | 0.230692281 | 1.33840668 | 24 | 5.68E-04 |
Energy dependent regulation of mTOR by LKB1-AMPK | 4.957992465 | 4.631542928 | 0.479499368 | 36661 | 19 | pathways | 11 | 0.166457128 | 0.185891173 | 3.471187386 | 21 | 0.001177552 |
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression | 5.956544373 | 4.623258145 | 0.428124414 | 178748 | 9 | pathways | 10 | 0.181519057 | 0.201778521 | 2.669507321 | 41 | 6.20E-04 |
ER-Phagosome pathway | 5.417486641 | 5.145557092 | 0.483620446 | 90340 | 24 | pathways | 11 | 0.214447684 | 0.246800875 | 8561.677396 | 38 | 0.001044433 |
Eukaryotic Translation Elongation | 5.666222222 | 4.482028671 | 0.503703704 | 23 | 2 | pathways | 13 | 0.163577959 | 0.177861279 | 0 | 1 | 6.19E-04 |
Extrinsic Pathway of Fibrin Clot Formation | 5.609036862 | 4.857898465 | 0.471962247 | 12178 | 8 | pathways | 15 | 0.132532533 | 0.144085467 | 0.733333333 | 34 | 8.83E-04 |
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis | 5.609569402 | 5.549536328 | 0.578411549 | 85558 | 12 | pathways | 11 | 0.211569191 | 0.240179525 | 1.487437988 | 37 | 6.57E-04 |
FCERI mediated NF-kB activation | 5.448086317 | 5.087077777 | 0.466230698 | 138918 | 32 | pathways | 11 | 0.214447684 | 0.246041991 | 624.6671105 | 37 | 9.59E-04 |
Formation of HIV elongation complex in the absence of HIV Tat | 5.857988167 | 4.831668103 | 0.444100061 | 6678 | 9 | pathways | 13 | 0.144952923 | 0.159551673 | 0.071428571 | 40 | 7.60E-04 |
Formation of HIV-1 elongation complex containing HIV-1 Tat | 5.898159748 | 4.664268993 | 0.400163782 | 12827 | 10 | pathways | 13 | 0.144952923 | 0.159551673 | 0.071428571 | 40 | 7.60E-04 |
Formation of RNA Pol II elongation complex | 5.857988167 | 4.831668103 | 0.444100061 | 6678 | 9 | pathways | 13 | 0.144952923 | 0.159551673 | 0.071428571 | 40 | 7.60E-04 |
Formation of tubulin folding intermediates by CCT/TriC | 5.38430304 | 5.733162533 | 0.70777655 | 439015 | 4 | pathways | 11 | 0.185486131 | 0.213739085 | 4.811335117 | 29 | 8.82E-04 |
G beta:gamma signalling through PI3Kgamma | 5.849961747 | 4.709086729 | 0.447852312 | 103148 | 28 | pathways | 11 | 0.214031684 | 0.250978331 | 1328.231514 | 33 | 0.001362434 |
G0 and Early G1 | 5.746609888 | 4.837113095 | 0.464739265 | 85653 | 20 | pathways | 9 | 0.209958769 | 0.24928008 | 1225.491273 | 24 | 0.001540261 |
G2 Phase | 5.606008757 | 4.895817018 | 0.479923413 | 28007 | 10 | pathways | 9 | 0.206681236 | 0.238605357 | 68.50837667 | 24 | 7.50E-04 |
G2/M Checkpoints | 5.53311438 | 5.481527693 | 0.549085496 | 128851 | 15 | pathways | 11 | 0.211569191 | 0.240179525 | 1.487437988 | 37 | 6.57E-04 |
GAB1 signalosome | 5.626021332 | 4.705546416 | 0.427713378 | 34931 | 14 | pathways | 13 | 0.197082465 | 0.233981502 | 1600.373489 | 14 | 0.001130938 |
Gap junction assembly | 5.373223465 | 5.732342285 | 0.708681478 | 472771 | 4 | pathways | 11 | 0.185486131 | 0.213739085 | 4.811335117 | 29 | 8.82E-04 |
GLI3 is processed to GLI3R by the proteasome | 5.435376239 | 5.313400914 | 0.524081955 | 98210 | 21 | pathways | 11 | 0.218987761 | 0.251792962 | 890.5519021 | 37 | 9.55E-04 |
Glycerophospholipid catabolism | 3.125 | 5.00909272 | 0.470238095 | 25 | 2 | pathways | 1 | 1 | 1 | 0 | 4 | 0.001317523 |
Glycogen storage disease type 0 (muscle GYS1) | 6.372004837 | 5.298839983 | 0.663636364 | 110 | 1 | pathways | 2 | 0.555555556 | 0.6 | 0 | 45 | 8.34E-04 |
Glycogen storage disease type IV (GBE1) | 6.372004837 | 5.298839983 | 0.663636364 | 110 | 1 | pathways | 2 | 0.555555556 | 0.6 | 0 | 45 | 8.34E-04 |
Glycogen storage disease type XV (GYG1) | 6.372004837 | 5.298839983 | 0.663636364 | 110 | 1 | pathways | 2 | 0.555555556 | 0.6 | 0 | 45 | 8.34E-04 |
Glycogen synthesis | 5.15993234 | 4.973072256 | 0.519318182 | 118 | 2 | pathways | 2 | 0.555555556 | 0.6 | 0 | 45 | 8.34E-04 |
GP1b-IX-V activation signalling | 6.041731414 | 4.631642616 | 0.439663696 | 6198 | 8 | pathways | 13 | 0.190723135 | 0.220114792 | 0.109219858 | 14 | 7.79E-04 |
HDL assembly | 4.805450879 | 4.742378414 | 0.462862123 | 9193 | 5 | pathways | 11 | 0.190284565 | 0.210013602 | 0 | 37 | 4.96E-04 |
Hedgehog ligand biogenesis | 5.590424388 | 5.499216393 | 0.563570209 | 80813 | 14 | pathways | 11 | 0.211569191 | 0.240179525 | 1.487437988 | 37 | 6.57E-04 |
Hedgehog 'off' state | 5.072677838 | 4.696485809 | 0.41969501 | 530452 | 21 | pathways | 11 | 0.216127979 | 0.250413065 | 9077.973977 | 29 | 0.00151098 |
Hedgehog 'on' state | 5.507566127 | 5.393730201 | 0.536056172 | 82055 | 18 | pathways | 11 | 0.211569191 | 0.240179525 | 1.487437988 | 37 | 6.57E-04 |
Hh mutants that don't undergo autocatalytic processing are degraded by ERAD | 5.602333068 | 5.528446914 | 0.570745722 | 80412 | 13 | pathways | 11 | 0.211569191 | 0.240179525 | 1.487437988 | 37 | 6.57E-04 |
HIV elongation arrest and recovery | 5.963322559 | 4.749029532 | 0.519316895 | 4063 | 6 | pathways | 13 | 0.144952923 | 0.159551673 | 0.071428571 | 40 | 7.60E-04 |
HSP90 chaperone cycle for steroid hormone receptors (SHR) | 5.317916995 | 5.127516136 | 0.527374575 | 520005 | 19 | pathways | 11 | 0.194648633 | 0.227429561 | 2066.302609 | 29 | 0.001927541 |
IL-6-type cytokine receptor ligand interactions | 5.924163877 | 4.60304312 | 0.433824991 | 23324 | 10 | pathways | 11 | 0.197907324 | 0.22392407 | 3.440938371 | 33 | 7.82E-04 |
Import of palmitoyl-CoA into the mitochondrial matrix | 5.268255811 | 4.598641753 | 0.421550358 | 23826 | 18 | pathways | 10 | 0.173162438 | 0.198285618 | 2022.699488 | 21 | 0.001827504 |
Inositol transporters | 5.433333333 | 5.068526169 | 0.666666667 | 3 | 1 | pathways | 1 | 1 | 1 | 0 | 6 | 0.001317523 |
Interactions of Tat with host cellular proteins | 6.500533816 | 4.794877239 | 0.484662863 | 5086 | 5 | pathways | 13 | 0.144952923 | 0.159551673 | 0.071428571 | 40 | 7.60E-04 |
Interleukin receptor SHC signaling | 5.892460211 | 4.661442889 | 0.443155274 | 62615 | 25 | pathways | 11 | 0.214031684 | 0.250978331 | 1328.231514 | 33 | 0.001362434 |
Interleukin-1 family signaling | 5.404528854 | 5.134572988 | 0.478763328 | 116868 | 35 | pathways | 11 | 0.214447684 | 0.246041991 | 624.6671105 | 37 | 9.59E-04 |
Interleukin-15 signaling | 5.767361761 | 4.45270656 | 0.432387277 | 14773 | 7 | pathways | 11 | 0.197907324 | 0.22392407 | 3.440938371 | 33 | 7.82E-04 |
Interleukin-19,20,22,24,26,28 and 29 signaling | 6.004648228 | 4.709450386 | 0.476097511 | 12029 | 8 | pathways | 11 | 0.197907324 | 0.22392407 | 3.440938371 | 33 | 7.82E-04 |
Interleukin-3, 5 and GM-CSF signaling | 5.905325556 | 4.783274336 | 0.460384288 | 68730 | 22 | pathways | 11 | 0.213893376 | 0.249971282 | 1072.742127 | 14 | 0.001166888 |
Interleukin-35 Signalling | 5.924163877 | 4.60304312 | 0.433824991 | 23324 | 10 | pathways | 11 | 0.197907324 | 0.22392407 | 3.440938371 | 33 | 7.82E-04 |
Interleukin-7 signaling | 5.913205871 | 4.835759922 | 0.484891416 | 87988 | 20 | pathways | 11 | 0.214447684 | 0.252564434 | 3305.231514 | 33 | 0.001749634 |
Intraflagellar transport | 5.082626724 | 5.599846756 | 0.662488549 | 405296 | 7 | pathways | 11 | 0.185590132 | 0.214746134 | 127.3666972 | 29 | 0.00109371 |
Intrinsic Pathway of Fibrin Clot Formation | 5.29823859 | 4.700024184 | 0.433236885 | 21638 | 15 | pathways | 13 | 0.179452426 | 0.202265442 | 4267.228226 | 34 | 0.001979882 |
IRAK2 mediated activation of TAK1 complex | 5.291308399 | 4.79632685 | 0.4379264 | 858 | 4 | pathways | 13 | 0.174808556 | 0.194212644 | 0 | 37 | 5.00E-04 |
IRF3 mediated activation of type 1 IFN | 4.594264906 | 4.850840161 | 0.584716689 | 4566 | 2 | pathways | 15 | 0.118319929 | 0.1281415 | 0 | 38 | 7.32E-04 |
Kinesins | 4.244023499 | 5.15943082 | 0.539834092 | 476690 | 22 | pathways | 11 | 0.186426359 | 0.219227504 | 1020.616384 | 29 | 0.001797486 |
L1CAM interactions | 4.996248905 | 4.659533495 | 0.444009881 | 1062 | 2 | pathways | 1 | 1 | 1 | 0 | 7 | 0.001317523 |
Linoleic acid (LA) metabolism | 4.547130758 | 4.879817053 | 0.533558398 | 368 | 6 | pathways | 15 | 0.094910394 | 0.103649485 | 1 | 8 | 0.001330163 |
Loss of Nlp from mitotic centrosomes | 4.928300437 | 4.759209984 | 0.445046803 | 220658 | 21 | pathways | 9 | 0.223422207 | 0.258344723 | 1467.388961 | 24 | 0.001131882 |
Loss of proteins required for interphase microtubule organization from the centrosome | 4.928300437 | 4.759209984 | 0.445046803 | 220658 | 21 | pathways | 9 | 0.223422207 | 0.258344723 | 1467.388961 | 24 | 0.001131882 |
Macroautophagy | 4.961086053 | 4.627525749 | 0.481945125 | 36749 | 20 | pathways | 11 | 0.166457128 | 0.185891173 | 3.471187386 | 21 | 0.001177552 |
MAPK3 (ERK1) activation | 5.684016204 | 4.597201445 | 0.412011655 | 39808 | 21 | pathways | 11 | 0.225246683 | 0.26408316 | 8265.840145 | 33 | 0.001151502 |
MAPK6/MAPK4 signaling | 5.269630552 | 5.10599165 | 0.485158082 | 110705 | 43 | pathways | 9 | 0.248032971 | 0.293409821 | 8517.307097 | 24 | 0.001776032 |
MET activates PI3K/AKT signaling | 6.406333697 | 4.862426235 | 0.466527112 | 22138 | 8 | pathways | 13 | 0.190723135 | 0.220114792 | 0.109219858 | 14 | 7.79E-04 |
Metabolism of ingested H2SeO4 and H2SeO3 into H2Se | 5.03683257 | 4.530200827 | 0.493484063 | 590 | 2 | pathways | 11 | 0.149065526 | 0.162276575 | 0 | 21 | 5.46E-04 |
Metabolism of ingested MeSeO2H into MeSeH | 5.03683257 | 4.530200827 | 0.493484063 | 590 | 2 | pathways | 11 | 0.149065526 | 0.162276575 | 0 | 21 | 5.46E-04 |
MHC class II antigen presentation | 4.90649583 | 4.949871847 | 0.466262209 | 492372 | 39 | pathways | 11 | 0.199457668 | 0.23814025 | 5668.198101 | 29 | 0.002871593 |
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane | 5.373223465 | 5.732342285 | 0.708681478 | 472771 | 4 | pathways | 11 | 0.185486131 | 0.213739085 | 4.811335117 | 29 | 8.82E-04 |
Mitochondrial Fatty Acid Beta-Oxidation | 4.25 | 5.485995242 | 0.75 | 8 | 2 | pathways | 1 | 1 | 1 | 1 | 36 | 0.001922529 |
Mitotic Prometaphase | 5.492965069 | 5.174052156 | 0.519287308 | 505573 | 18 | pathways | 11 | 0.190943179 | 0.2230453 | 317.7042437 | 29 | 0.001461676 |
Mitotic Prophase | 5.390304905 | 4.63353775 | 0.402248115 | 13697 | 6 | pathways | 11 | 0.20152207 | 0.230692281 | 1.33840668 | 24 | 5.68E-04 |
Myoclonic epilepsy of Lafora | 5.15993234 | 4.973072256 | 0.519318182 | 118 | 2 | pathways | 2 | 0.555555556 | 0.6 | 0 | 45 | 8.34E-04 |
Neddylation | 5.349414867 | 5.106880797 | 0.488463185 | 88518 | 28 | pathways | 9 | 0.221627051 | 0.254645615 | 3079.21335 | 37 | 8.69E-04 |
Negative regulators of DDX58/IFIH1 signaling | 4.644635542 | 4.687614541 | 0.412344355 | 40320 | 5 | pathways | 15 | 0.118319929 | 0.1281415 | 0 | 38 | 7.32E-04 |
Nephrin family interactions | 5.813582444 | 4.789191952 | 0.466219996 | 32647 | 10 | pathways | 13 | 0.190723135 | 0.220114792 | 0.109219858 | 14 | 7.79E-04 |
N-glycan trimming and elongation in the cis-Golgi | 6.173104445 | 5.212964223 | 0.666666667 | 9 | 1 | pathways | 1 | 1 | 1 | 0 | 44 | 0.001317523 |
NIK-->noncanonical NF-kB signaling | 5.537092905 | 5.384409757 | 0.54081763 | 90986 | 17 | pathways | 11 | 0.211569191 | 0.240179525 | 1.487437988 | 37 | 6.57E-04 |
NOTCH2 Activation and Transmission of Signal to the Nucleus | 6.084297883 | 4.77839996 | 0.494077049 | 74564 | 8 | pathways | 11 | 0.14604015 | 0.157957052 | 0 | 41 | 5.97E-04 |
Notch-HLH transcription pathway | 6.508350114 | 4.604547408 | 0.447185672 | 30243 | 8 | pathways | 13 | 0.138118089 | 0.147603261 | 0 | 41 | 6.63E-04 |
Nuclear import of Rev protein | 4.644848628 | 4.579505674 | 0.413747646 | 466 | 3 | pathways | 12 | 0.133602422 | 0.142535465 | 0 | 41 | 6.66E-04 |
Orc1 removal from chromatin | 5.532780576 | 5.379424695 | 0.53495547 | 107671 | 24 | pathways | 9 | 0.232199228 | 0.273779552 | 1626.493117 | 24 | 0.001209324 |
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha | 5.522227118 | 5.209830105 | 0.519769545 | 88129 | 19 | pathways | 11 | 0.211569191 | 0.240179525 | 1.487437988 | 37 | 6.57E-04 |
p53-Dependent G1 DNA Damage Response | 5.67010207 | 4.8743607 | 0.444098444 | 37557 | 15 | pathways | 9 | 0.207069127 | 0.240997099 | 161.4351984 | 24 | 0.001117658 |
Pausing and recovery of HIV elongation | 5.963322559 | 4.749029532 | 0.519316895 | 4063 | 6 | pathways | 13 | 0.144952923 | 0.159551673 | 0.071428571 | 40 | 7.60E-04 |
Pausing and recovery of Tat-mediated HIV elongation | 5.791416781 | 4.5473345 | 0.434219686 | 5118 | 7 | pathways | 13 | 0.144952923 | 0.159551673 | 0.071428571 | 40 | 7.60E-04 |
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes | 5.634579903 | 4.88896557 | 0.42814426 | 25648 | 12 | pathways | 9 | 0.206939669 | 0.239990049 | 88.09814396 | 24 | 9.32E-04 |
Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes | 5.666688948 | 4.901740455 | 0.505915564 | 20364 | 9 | pathways | 11 | 0.202260923 | 0.233587548 | 19.30755746 | 24 | 7.50E-04 |
PI3K events in ERBB2 signaling | 5.491660921 | 4.628642743 | 0.42533764 | 39274 | 13 | pathways | 13 | 0.197082465 | 0.233981502 | 1600.373489 | 14 | 0.001130938 |
PI3K events in ERBB4 signaling | 5.965164307 | 4.639382379 | 0.467323188 | 15168 | 7 | pathways | 13 | 0.190723135 | 0.220114792 | 0.109219858 | 14 | 7.79E-04 |
PI3K/AKT activation | 5.829271281 | 4.7135968 | 0.456995961 | 31538 | 10 | pathways | 13 | 0.190723135 | 0.220114792 | 0.109219858 | 14 | 7.79E-04 |
Post-chaperonin tubulin folding pathway | 5.38430304 | 5.733162533 | 0.70777655 | 439015 | 4 | pathways | 11 | 0.185486131 | 0.213739085 | 4.811335117 | 29 | 8.82E-04 |
Potassium transport channels | 5.82007141 | 5.156015796 | 0.485869565 | 465 | 2 | pathways | 3 | 0.5 | 0.583333333 | 0 | 39 | 7.47E-04 |
PRC2 methylates histones and DNA | 5.747794008 | 4.69126885 | 0.526924301 | 1939 | 10 | pathways | 10 | 0.181818182 | 0.204170263 | 248.3586063 | 41 | 0.001161106 |
Prefoldin mediated transfer of substrate to CCT/TriC | 5.383796542 | 5.654696243 | 0.665206943 | 371513 | 5 | pathways | 11 | 0.185486131 | 0.213739085 | 4.811335117 | 29 | 8.82E-04 |
Pre-NOTCH Processing in Golgi | 7.304646743 | 4.700319955 | 0.551856553 | 660 | 8 | pathways | 13 | 0.138118089 | 0.147603261 | 0 | 41 | 6.63E-04 |
Pre-NOTCH Processing in the Endoplasmic Reticulum | 8.122146213 | 4.975438918 | 0.7575 | 47 | 4 | pathways | 13 | 0.138118089 | 0.147603261 | 0 | 41 | 6.63E-04 |
PTK6 Regulates Cell Cycle | 5.515820423 | 4.870754362 | 0.461958144 | 31348 | 19 | pathways | 9 | 0.217548472 | 0.252882079 | 788.4139813 | 24 | 0.001367883 |
Reactions specific to the hybrid N-glycan synthesis pathway | 6.589125121 | 5.636982641 | 0.870967742 | 31 | 1 | pathways | 1 | 1 | 1 | 0 | 43 | 0.001317523 |
Recruitment of mitotic centrosome proteins and complexes | 4.94694664 | 4.766636213 | 0.445722781 | 220940 | 23 | pathways | 9 | 0.223422207 | 0.258344723 | 1467.388961 | 24 | 0.001131882 |
Recruitment of NuMA to mitotic centrosomes | 5.083469874 | 5.072240427 | 0.528962586 | 558381 | 23 | pathways | 9 | 0.226634714 | 0.26418381 | 4297.290835 | 29 | 0.001814454 |
Recycling pathway of L1 | 4.911440721 | 5.214763113 | 0.540101441 | 987148 | 18 | pathways | 11 | 0.185486131 | 0.213739085 | 4.811335117 | 29 | 8.82E-04 |
Regulation of activated PAK-2p34 by proteasome mediated degradation | 5.580019558 | 5.543016738 | 0.575046276 | 80658 | 12 | pathways | 11 | 0.211569191 | 0.240179525 | 1.487437988 | 37 | 6.57E-04 |
Regulation of APC/C activators between G1/S and early anaphase | 5.59165446 | 4.847451037 | 0.473186319 | 41693 | 14 | pathways | 9 | 0.206939669 | 0.239990049 | 122.510766 | 24 | 9.34E-04 |
Regulation of IFNA signaling | 5.607358608 | 4.626052708 | 0.431041775 | 27409 | 12 | pathways | 11 | 0.197907324 | 0.22392407 | 3.440938371 | 33 | 7.82E-04 |
Regulation of IFNG signaling | 5.756222929 | 4.589517964 | 0.426680757 | 46487 | 12 | pathways | 11 | 0.197907324 | 0.22392407 | 3.440938371 | 33 | 7.82E-04 |
Regulation of innate immune responses to cytosolic DNA | 4.594264906 | 4.850840161 | 0.584716689 | 2283 | 2 | pathways | 15 | 0.118319929 | 0.1281415 | 0 | 38 | 7.32E-04 |
Regulation of necroptotic cell death | 5.1762272 | 4.534373559 | 0.40441792 | 3928 | 7 | pathways | 13 | 0.165541385 | 0.184511402 | 0 | 38 | 5.66E-04 |
Regulation of ornithine decarboxylase (ODC) | 5.59336485 | 5.481001802 | 0.562145778 | 80352 | 13 | pathways | 11 | 0.211569191 | 0.240179525 | 1.487437988 | 37 | 6.57E-04 |
Regulation of PLK1 Activity at G2/M Transition | 4.998507037 | 4.682856842 | 0.421976164 | 235552 | 23 | pathways | 9 | 0.223422207 | 0.258344723 | 1467.388961 | 24 | 0.001131882 |
Regulation of PTEN stability and activity | 5.653071602 | 5.140065517 | 0.462479596 | 121446 | 28 | pathways | 11 | 0.211569191 | 0.240179525 | 1.487437988 | 37 | 6.57E-04 |
Regulation of RAS by GAPs | 5.569187294 | 5.483699157 | 0.554339311 | 79696 | 14 | pathways | 11 | 0.211569191 | 0.240179525 | 1.487437988 | 37 | 6.57E-04 |
Regulation of RUNX3 expression and activity | 5.543247364 | 5.365963741 | 0.530087065 | 104578 | 19 | pathways | 11 | 0.212111503 | 0.242319505 | 604.9797291 | 24 | 9.38E-04 |
Regulation of signaling by CBL | 6.027762978 | 4.863924364 | 0.498427071 | 99232 | 15 | pathways | 13 | 0.190723135 | 0.220114792 | 0.109219858 | 14 | 7.79E-04 |
Removal of aminoterminal propeptides from gamma-carboxylated proteins | 5.413049135 | 4.786073549 | 0.415007513 | 21134 | 10 | pathways | 15 | 0.132532533 | 0.144085467 | 0.733333333 | 34 | 8.83E-04 |
Resolution of Sister Chromatid Cohesion | 5.478203073 | 5.040906332 | 0.489262208 | 523006 | 24 | pathways | 11 | 0.220887554 | 0.260387049 | 2594.035708 | 29 | 0.00183167 |
RHO GTPases activate IQGAPs | 5.222641575 | 5.126563723 | 0.501320588 | 665308 | 14 | pathways | 11 | 0.185486131 | 0.213739085 | 4.811335117 | 29 | 8.82E-04 |
RNA Polymerase II Pre-transcription Events | 5.768284892 | 4.872095237 | 0.481194495 | 6714 | 12 | pathways | 11 | 0.159096371 | 0.182225089 | 1229.415231 | 40 | 0.001304144 |
RNA Polymerase II Transcription Elongation | 5.857988167 | 4.831668103 | 0.444100061 | 6678 | 9 | pathways | 13 | 0.144952923 | 0.159551673 | 0.071428571 | 40 | 7.60E-04 |
RNA Polymerase III Abortive And Retractive Initiation | 3.432857143 | 4.513371542 | 0.511904762 | 17 | 2 | pathways | 13 | 0.161266748 | 0.175402401 | 0 | 40 | 5.55E-04 |
RNA Polymerase III Transcription Initiation From Type 3 Promoter | 3.58 | 4.739810024 | 0.666666667 | 6 | 1 | pathways | 13 | 0.161266748 | 0.175402401 | 0 | 40 | 5.55E-04 |
Role of LAT2/NTAL/LAB on calcium mobilization | 5.659175589 | 4.574870884 | 0.410324074 | 46571 | 13 | pathways | 13 | 0.190723135 | 0.220114792 | 0.109219858 | 14 | 7.79E-04 |
RUNX1 regulates transcription of genes involved in differentiation of HSCs | 5.482697201 | 5.257889863 | 0.491922846 | 380586 | 23 | pathways | 11 | 0.211569191 | 0.240179525 | 1.487437988 | 37 | 6.57E-04 |
RUNX3 regulates BCL2L11 (BIM) transcription | 4.797148559 | 4.35631325 | 0.427380602 | 67997 | 3 | pathways | 13 | 0.143819248 | 0.155561349 | 0 | 33 | 6.14E-04 |
SCF(Skp2)-mediated degradation of p27/p21 | 5.578814672 | 5.240792166 | 0.520947771 | 122869 | 34 | pathways | 9 | 0.238043869 | 0.283393277 | 5097.166652 | 24 | 0.002013014 |
SCF-beta-TrCP mediated degradation of Emi1 | 5.610251149 | 5.570576799 | 0.58219255 | 79596 | 11 | pathways | 11 | 0.211569191 | 0.240179525 | 1.487437988 | 37 | 6.57E-04 |
Separation of Sister Chromatids | 5.562742863 | 5.409959222 | 0.556711946 | 585169 | 29 | pathways | 11 | 0.229303776 | 0.27022736 | 4035.995473 | 29 | 0.001921366 |
Signaling by cytosolic FGFR1 fusion mutants | 5.645575932 | 4.808851012 | 0.430646079 | 19720 | 13 | pathways | 13 | 0.192162554 | 0.223991932 | 518.4074414 | 14 | 0.001286799 |
Signaling by NOTCH3 | 5.80540604 | 4.741348748 | 0.41858347 | 74598 | 7 | pathways | 11 | 0.147078427 | 0.162084156 | 326.0280783 | 41 | 0.001062084 |
Signaling by NOTCH4 | 5.88715604 | 4.800915165 | 0.49358347 | 74560 | 7 | pathways | 11 | 0.14604015 | 0.157957052 | 0 | 41 | 5.97E-04 |
Signalling to ERK5 | 5.441198313 | 4.987600586 | 0.515449915 | 504 | 2 | pathways | 11 | 0.164064436 | 0.178123106 | 0 | 11 | 5.64E-04 |
STAT6-mediated induction of chemokines | 4.876020988 | 4.618874124 | 0.474936574 | 2655 | 3 | pathways | 15 | 0.118319929 | 0.1281415 | 0 | 38 | 7.32E-04 |
Synthesis of PE | 4.703319967 | 5.04183147 | 0.610801097 | 207 | 3 | pathways | 2 | 0.666666667 | 0.75 | 0 | 23 | 0.00101502 |
Synthesis of PG | 6.001822698 | 4.560321061 | 0.545157129 | 759 | 3 | pathways | 13 | 0.173798897 | 0.190202429 | 58.66796455 | 13 | 7.63E-04 |
Synthesis of PI | 5.725371921 | 6.129281356 | 1 | 2 | 1 | pathways | 1 | 1 | 1 | 0 | 19 | 0.001317523 |
Synthesis of PIPs at the plasma membrane | 5.738460022 | 4.685984766 | 0.44587985 | 47162 | 25 | pathways | 13 | 0.202632384 | 0.23582656 | 5294.029994 | 14 | 0.001091662 |
Synthesis of very long-chain fatty acyl-CoAs | 5.336866322 | 4.90323439 | 0.494631212 | 854 | 7 | pathways | 13 | 0.11689917 | 0.129971049 | 3937 | 8 | 0.001738168 |
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) | 6.12647015 | 4.391650342 | 0.471123586 | 9854 | 6 | pathways | 15 | 0.119602529 | 0.129343781 | 0 | 32 | 6.38E-04 |
Tat-mediated HIV elongation arrest and recovery | 5.791416781 | 4.5473345 | 0.434219686 | 5118 | 7 | pathways | 13 | 0.144952923 | 0.159551673 | 0.071428571 | 40 | 7.60E-04 |
TBC/RABGAPs | 4.857112782 | 4.667200524 | 0.447247147 | 930 | 3 | pathways | 15 | 0.120254314 | 0.130169604 | 0 | 14 | 7.44E-04 |
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation | 5.020272272 | 4.531999665 | 0.410043942 | 146 | 3 | pathways | 12 | 0.133602422 | 0.142535465 | 0 | 41 | 6.66E-04 |
The role of GTSE1 in G2/M progression after G2 checkpoint | 5.451823581 | 5.360231083 | 0.544099788 | 656895 | 32 | pathways | 11 | 0.244190336 | 0.292983079 | 11650.48723 | 29 | 0.002048528 |
TNFR2 non-canonical NF-kB pathway | 5.462302187 | 5.260117528 | 0.52481871 | 82721 | 20 | pathways | 11 | 0.211569191 | 0.240179525 | 1.487437988 | 37 | 6.57E-04 |
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 | 5.633076653 | 4.714017113 | 0.442310132 | 59720 | 15 | pathways | 9 | 0.207979893 | 0.242406968 | 765.3077115 | 41 | 9.90E-04 |
Translocation of GLUT4 to the plasma membrane | 5.073727885 | 4.87595529 | 0.47677766 | 514138 | 29 | pathways | 11 | 0.196264453 | 0.233281237 | 4717.013289 | 29 | 0.002110873 |
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus | 5.300635097 | 4.827210006 | 0.447664094 | 20650 | 9 | pathways | 15 | 0.132532533 | 0.144085467 | 0.733333333 | 34 | 8.83E-04 |
Transport of vitamins, nucleosides, and related molecules | 8.709470199 | 5.246358395 | 0.688741722 | 151 | 1 | pathways | 1 | 1 | 1 | 0 | 47 | 0.001317523 |
Triglyceride biosynthesis | 5.475699042 | 4.994901799 | 0.610421595 | 1445 | 4 | pathways | 13 | 0.163577959 | 0.178314452 | 330 | 1 | 0.001058903 |
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A | 5.544670543 | 5.430415482 | 0.548650151 | 96213 | 15 | pathways | 11 | 0.211569191 | 0.240179525 | 1.487437988 | 37 | 6.57E-04 |
Ubiquitin-dependent degradation of Cyclin D1 | 5.546771393 | 5.335998253 | 0.548263534 | 96066 | 19 | pathways | 9 | 0.231387627 | 0.267305663 | 2630.551651 | 24 | 0.001277199 |
UCH proteinases | 5.380333785 | 5.268900541 | 0.499832055 | 86112 | 23 | pathways | 11 | 0.211569191 | 0.240179525 | 1.487437988 | 37 | 6.57E-04 |
Uptake and function of diphtheria toxin | 4.861916407 | 4.459217514 | 0.438853819 | 12017 | 8 | pathways | 9 | 0.189630478 | 0.210753249 | 2422.799812 | 21 | 8.83E-04 |
Vif-mediated degradation of APOBEC3G | 5.558524716 | 5.526305478 | 0.578837752 | 79620 | 12 | pathways | 11 | 0.211569191 | 0.240179525 | 1.487437988 | 37 | 6.57E-04 |
Vpu mediated degradation of CD4 | 5.589165953 | 5.529447677 | 0.570913879 | 79645 | 12 | pathways | 11 | 0.211569191 | 0.240179525 | 1.487437988 | 37 | 6.57E-04 |
Peptide N-myristoyltransferase 1 | 5.955554682 | 4.878210776 | 0.519031142 | 289 | | targets | 16 | 0.115210581 | 0.122244127 | 0 | 37 | 7.78E-04 |
Serine/threonine-protein kinase WEE1 | 6.174809824 | 5.070685293 | 0.541798942 | 945 | | targets | 10 | 0.20109356 | 0.229971107 | 510.6927219 | 24 | 0.001649634 |
LIM domain kinase 2 | 6.272839261 | 5.049754309 | 0.528481013 | 316 | | targets | 14 | 0.137173643 | 0.154269367 | 701.3302368 | 26 | 0.00157063 |
Epithelial discoidin domain-containing receptor 1 | 6.150603077 | 5.061730153 | 0.557312253 | 253 | | targets | 1 | 1 | 1 | 0 | 10 | 0.001317523 |
Mitogen-activated protein kinase 7 | 5.328103747 | 5.089473416 | 0.547368421 | 190 | | targets | 10 | 0.196206283 | 0.222598067 | 2831.836781 | 11 | 0.002582206 |
Receptor-interacting serine/threonine-protein kinase 1 | 5.895124237 | 5.283840135 | 0.632411067 | 253 | | targets | 12 | 0.198322349 | 0.237548064 | 9497.438604 | 38 | 0.007361133 |
Heat shock protein HSP90 | 5.288255918 | 4.950150449 | 0.505646817 | 3896 | | targets | 10 | 0.194591417 | 0.216046252 | 1542.992734 | 26 | 0.001209182 |
Voltage-gated potassium channel subunit Kv1.1 | 7.367596965 | 4.987803586 | 0.54954955 | 111 | | targets | 2 | 0.666666667 | 0.75 | 0 | 12 | 0.00101502 |
Peptidyl-prolyl cis-trans isomerase FKBP5 | 4.898663924 | 5.299735405 | 0.721311475 | 122 | | targets | 12 | 0.162973904 | 0.179820159 | 0 | 29 | 4.32E-04 |
Splicing factor 3B subunit 3 | 5.4830531 | 5.334355662 | 0.537313433 | 67 | | targets | 12 | 0.153382762 | 0.165461913 | 661 | 1 | 0.001293566 |
FK506 binding protein 4 | 4.425355575 | 4.835578779 | 0.524822695 | 141 | | targets | 12 | 0.163054187 | 0.180827208 | 28.12911538 | 1 | 8.04E-04 |
Voltage-gated potassium channel subunit Kv1.3 | 7.39490013 | 5.03733758 | 0.542769857 | 982 | | targets | 2 | 0.666666667 | 0.75 | 0 | 12 | 0.00101502 |
Coagulation factor XI | 6.062501393 | 4.92399866 | 0.529595016 | 642 | | targets | 14 | 0.152183908 | 0.164901966 | 0 | 34 | 5.34E-04 |
Lysosomal Pro-X carboxypeptidase | 7.233270435 | 5.076435199 | 0.589635854 | 714 | | targets | 12 | 0.198322349 | 0.223811431 | 2965.851866 | 34 | 8.29E-04 |
CaM kinase II | 5.1453528 | 4.709446103 | 0.520833333 | 576 | | targets | 12 | 0.188603989 | 0.219292297 | 7209.462958 | 26 | 0.004155108 |
PI3-kinase p85-alpha subunit | 5.571666667 | 4.994974485 | 0.583333333 | 12 | | targets | 12 | 0.235085227 | 0.301092278 | 15261.09251 | 14 | 0.010226283 |
Cathepsin S | 6.875522866 | 5.061229205 | 0.572948328 | 2632 | | targets | 12 | 0.199037883 | 0.23057125 | 8201.69185 | 1 | 0.002435823 |
Renin | 7.356424366 | 5.189347655 | 0.596947195 | 4848 | | targets | 1 | 1 | 1 | 0 | 9 | 0.001317523 |
Tubulin | 5.195950254 | 5.719218319 | 0.723160327 | 33756 | | targets | 10 | 0.227179135 | 0.285743658 | 13556.99764 | 29 | 0.006520354 |
Tubulin beta-1 chain | 5.329488522 | 5.384018276 | 0.603896104 | 154 | | targets | 10 | 0.218050066 | 0.267370402 | 4225.896489 | 29 | 0.004792862 |
Tubulin beta-3 chain | 7.902222222 | 6.742505615 | 0.777777778 | 9 | | targets | 10 | 0.218050066 | 0.267370402 | 4225.896489 | 29 | 0.004792862 |
Nuclear receptor subfamily 2 group C member 2 | 4.954656933 | 5.13367799 | 0.565217391 | 23 | | targets | 12 | 0.132188498 | 0.145348173 | 0 | 21 | 5.78E-04 |
Phospholipase D2 | 6.11905836 | 5.055164875 | 0.557065217 | 368 | | targets | 14 | 0.170005136 | 0.190154818 | 1272.679804 | 13 | 0.001013888 |
Phospholipase D1 | 6.556409733 | 5.117222772 | 0.57840617 | 389 | | targets | 12 | 0.21015873 | 0.23930021 | 7741.525322 | 13 | 0.001309136 |
Apoptosis regulator Bcl-2 | 7.273133156 | 5.558130417 | 0.67490953 | 1658 | | targets | 12 | 0.195050088 | 0.220079354 | 1996.976044 | 33 | 0.001629646 |
Phosphodiesterase 7 | 4.943009886 | 4.7172484 | 0.524590164 | 122 | | targets | 14 | 0.135711357 | 0.14989001 | 0 | 32 | 5.53E-04 |
Histone deacetylase 3/NCoR1 | 6.562121251 | 4.990224063 | 0.55 | 80 | | targets | 10 | 0.193002915 | 0.23385604 | 8625.672905 | 41 | 0.005792516 |
Dipeptidyl peptidase I | 7.521812489 | 4.867804764 | 0.545576408 | 746 | | targets | 10 | 0.201829268 | 0.22905757 | 1140.395959 | 1 | 0.001453668 |
G1/S-specific cyclin D1 | 4.181818182 | 5.329521329 | 0.727272727 | 11 | | targets | 10 | 0.227804542 | 0.261316118 | 6600.803038 | 41 | 0.002740699 |
Epidermal growth factor receptor | 5.776187152 | 5.274367708 | 0.657608696 | 736 | | targets | 12 | 0.187429219 | 0.238398661 | 18441.28728 | 14 | 0.012844805 |
Cannabinoid CB1 receptor/orexin receptor 1 complex | 5.933538486 | 5.808740011 | 0.777777778 | 36 | | targets | 14 | 0.170092497 | 0.194054137 | 1604.832197 | 34 | 0.001705009 |
Brain adenylate cyclase 1 | 6.12115109 | 5.060410299 | 0.547945205 | 219 | | targets | 12 | 0.184503902 | 0.216437192 | 12279.77014 | 37 | 0.004279862 |
p53-binding protein Mdm-2 | 7.043004408 | 4.989967368 | 0.508978328 | 3230 | | targets | 10 | 0.189467659 | 0.213297847 | 709.9204396 | 24 | 0.001321351 |
Carnitine palmitoyltransferase 2 | 4.456271554 | 5.057507282 | 0.55785124 | 968 | | targets | 11 | 0.155107779 | 0.173711271 | 61.16328887 | 21 | 6.97E-04 |
Carnitine O-palmitoyltransferase 1- liver isoform | 6.881037429 | 5.141335846 | 0.586826347 | 501 | | targets | 11 | 0.155326138 | 0.176103013 | 368.2342782 | 21 | 0.001310208 |
Opioid receptors; delta & kappa | 8.263566137 | 5.274745519 | 0.590909091 | 88 | | targets | 12 | 0.197258641 | 0.222796589 | 1746.503154 | 34 | 0.001050006 |
Matrix metalloproteinase 15 | 5.440391999 | 4.705461579 | 0.510638298 | 47 | | targets | 14 | 0.142857143 | 0.154518732 | 0 | 1 | 5.96E-04 |
Matrix metalloproteinase 17 | 5.390024865 | 5.079351806 | 0.535714286 | 28 | | targets | 14 | 0.141091219 | 0.151323748 | 0 | 1 | 6.48E-04 |
Topoisomerase (DNA) II binding protein 1 | 4.301029996 | 6.458783012 | 1 | 18 | | targets | 10 | 0.177100054 | 0.202600345 | 1990.101354 | 40 | 0.001998679 |
Calcitonin-gene-related peptide receptor- CALCRL/RAMP1 | 7.581577841 | 5.603085486 | 0.75210084 | 238 | | targets | 14 | 0.135767022 | 0.150897059 | 109.3333333 | 32 | 9.09E-04 |
Transient receptor potential cation channel subfamily V member 6 | 3.972766481 | 4.838680067 | 0.611764706 | 85 | | targets | 14 | 0.142121082 | 0.153902186 | 0 | 38 | 6.86E-04 |
ORAI 1/2/3 | 4.479092494 | 5.812556124 | 0.780487805 | 246 | | targets | 14 | 0.166081284 | 0.18569323 | 871.0607973 | 26 | 0.001298626 |
Neutral sphingomyelinase | 4.659365847 | 4.677647413 | 0.62745098 | 51 | | targets | 1 | 1 | 1 | 3 | 15 | 0.002527534 |
Group IID secretory phospholipase A2 | 6.121725893 | 4.887311015 | 0.552631579 | 38 | | targets | 14 | 0.149099099 | 0.165765151 | 1312.25 | 13 | 0.001853198 |
RAS guanyl releasing protein 3 | 6.815925926 | 5.052655106 | 0.530864198 | 81 | | targets | 12 | 0.173298429 | 0.19442717 | 661 | 33 | 9.85E-04 |
Phosphodiesterase 6 | 5.798482476 | 5.00565894 | 0.548523207 | 1422 | | targets | 14 | 0.149570718 | 0.165517204 | 3293 | 37 | 0.002384674 |
AMP deaminase 3 | 6.243506087 | 4.969947562 | 0.551020408 | 49 | | targets | 12 | 0.195165094 | 0.219029745 | 661 | 1 | 0.001034581 |
Folate receptor beta | 5.754571875 | 5.186906338 | 0.566037736 | 53 | | targets | 1 | 1 | 1 | 1 | 16 | 0.001922529 |
Histone-lysine N-methyltransferase EZH2 | 6.791897877 | 5.154563422 | 0.61013986 | 572 | | targets | 11 | 0.167510121 | 0.191390382 | 82.2067606 | 41 | 0.001376526 |
Coagulation factor IX | 6.054617914 | 5.018343521 | 0.575980392 | 408 | | targets | 14 | 0.152464302 | 0.168930163 | 962.3550349 | 34 | 0.002034992 |
Vacuolar ATP synthase subunit S1 | 5.226666667 | 4.97722522 | 0.541666667 | 24 | | targets | 1 | 1 | 1 | 3 | 17 | 0.002527534 |
Serine/threonine-protein kinase SMG1 | 7.050937748 | 5.123168881 | 0.564102564 | 39 | | targets | 1 | 1 | 1 | 0 | 18 | 0.001317523 |
Membrane-associated phosphatidylinositol transfer protein 1 | 5.725371921 | 6.129281356 | 1 | 2 | | targets | 1 | 1 | 1 | 0 | 19 | 0.001317523 |
14-3-3 protein sigma | 5.525488303 | 4.992909501 | 0.642857143 | 14 | | targets | 10 | 0.193793911 | 0.218476958 | 1675.488093 | 24 | 0.001755554 |
Amiloride-sensitive cation channel 2- neuronal | 5.09760039 | 4.711949628 | 0.542857143 | 35 | | targets | 2 | 0.666666667 | 0.75 | 0 | 20 | 0.00101502 |
PPAR alpha/gamma | 7.579824313 | 4.416193248 | 0.555555556 | 18 | | targets | 10 | 0.177479893 | 0.211793867 | 11917.06948 | 41 | 0.004134245 |
Pyruvate dehydrogenase kinase isoform 3 | 4.454136082 | 6.864411928 | 1 | 2 | | targets | 12 | 0.130366286 | 0.142106433 | 0.840909091 | 21 | 8.74E-04 |
Matrix metalloproteinase 11 | 6.615906516 | 4.803069241 | 0.531914894 | 47 | | targets | 14 | 0.14316609 | 0.157665761 | 337.1107489 | 1 | 0.001482069 |
Tubulin beta-2 chain | 5.369784594 | 5.254238494 | 0.541666667 | 24 | | targets | 10 | 0.225630539 | 0.282646981 | 10921.73961 | 29 | 0.006241673 |
Carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 | 4.541742977 | 5.152368422 | 0.75 | 4 | | targets | 1 | 1 | 1 | 0 | 22 | 0.001317523 |
26S proteosome | 5.753768482 | 5.902813128 | 0.671882409 | 2109 | | targets | 10 | 0.268016194 | 0.340202249 | 42086.40357 | 37 | 0.015483558 |
Phosphoenolpyruvate carboxykinase cytosolic | 5.757805299 | 5.429483925 | 0.72 | 25 | | targets | 11 | 0.165252122 | 0.184944667 | 1321 | 24 | 0.001537734 |
Elongation factor 1-alpha 1 | 4.973333333 | 4.396340865 | 0.555555556 | 9 | | targets | 12 | 0.195510927 | 0.222050893 | 2086.922664 | 1 | 0.002476051 |
Group IIE secretory phospholipase A2 | 6.904849507 | 5.243000338 | 0.638888889 | 36 | | targets | 14 | 0.149099099 | 0.165765151 | 1312.25 | 13 | 0.001853198 |
Group IIF secretory phospholipase A2 | 6.170082866 | 5.289942032 | 0.714285714 | 28 | | targets | 14 | 0.149099099 | 0.165765151 | 1312.25 | 13 | 0.001853198 |
Choline kinase alpha | 5.083747317 | 5.266152159 | 0.688073394 | 109 | | targets | 1 | 1 | 1 | 1 | 23 | 0.001922529 |
Sulfonylurea receptor 1 | 7.4575 | 5.369721854 | 0.75 | 8 | | targets | 12 | 0.180381471 | 0.200405326 | 1358.930447 | 37 | 0.001941968 |
ATP-binding cassette sub-family B member 5 | 5 | 6.890934648 | 1 | 4 | | targets | 12 | 0.175132275 | 0.190953449 | 0 | 37 | 5.19E-04 |
Transcription intermediary factor 1-alpha | 4.10140056 | 5.049379068 | 0.571428571 | 28 | | targets | 12 | 0.177670424 | 0.199851449 | 136.7575877 | 14 | 8.82E-04 |
Bromodomain and PHD finger-containing protein 3 | 3.025 | 5.579885375 | 1 | 8 | | targets | 10 | 0.182974019 | 0.200885964 | 751.5063794 | 41 | 0.001059942 |
Kinase suppressor of Ras 2 | 3.376603843 | 5.266377038 | 1 | 3 | | targets | 12 | 0.166834677 | 0.187625391 | 593.1312728 | 33 | 0.001715308 |
cAMP-dependent protein kinase- gamma catalytic subunit | 4.504117761 | 5.112565742 | 0.625 | 8 | | targets | 10 | 0.234918382 | 0.278991632 | 15651.02677 | 37 | 0.007709609 |
CDK2/Cyclin A1 | 6.375077591 | 5.965260444 | 1 | 12 | | targets | 10 | 0.232117812 | 0.281847936 | 6213.620881 | 24 | 0.005572693 |
CDK1/Cyclin A | 6.206100468 | 5.782791525 | 0.857142857 | 14 | | targets | 10 | 0.249246988 | 0.316304608 | 21842.78767 | 24 | 0.010026737 |
Serine/threonine-protein kinase A-Raf | 5.476036192 | 5.143249091 | 0.5625 | 16 | | targets | 12 | 0.167003027 | 0.189639489 | 1402.268384 | 33 | 0.002329693 |
CDK1/Cyclin E | 5.524414986 | 5.960846209 | 0.666666667 | 6 | | targets | 10 | 0.242313324 | 0.304917758 | 14185.58244 | 24 | 0.009328002 |
CDK3/Cyclin E | 5.65073994 | 5.746768356 | 0.666666667 | 12 | | targets | 10 | 0.201460743 | 0.233676809 | 240.9634065 | 24 | 0.002156557 |
CDK4/Cyclin D3 | 4.450295589 | 4.964182283 | 0.6 | 10 | | targets | 9 | 0.226247437 | 0.260558433 | 5650.781621 | 24 | 0.002856979 |
Atrial natriuretic peptide receptor | 7.514646458 | 4.764009678 | 0.555555556 | 36 | | targets | 1 | 1 | 1 | 0 | 25 | 0.001317523 |
Tripeptidyl-peptidase 2 | 5.575218252 | 5.448346879 | 0.8 | 5 | | targets | 12 | 0.174762408 | 0.189971576 | 0 | 37 | 5.05E-04 |
Thyroid hormone receptor | 7.818221344 | 5.140023162 | 0.608695652 | 46 | | targets | 12 | 0.132188498 | 0.145348173 | 0 | 21 | 5.78E-04 |
Breakpoint cluster region protein | 4.411873459 | 5.049101684 | 0.534883721 | 172 | | targets | 14 | 0.16138469 | 0.179986617 | 2.569622163 | 14 | 9.11E-04 |
Calcitonin gene-related peptide 1 | 6.171825761 | 4.6376437 | 0.572413793 | 145 | | targets | 14 | 0.135767022 | 0.150897059 | 109.3333333 | 32 | 9.09E-04 |
Cathepsin F | 6.026790139 | 4.76527678 | 0.535714286 | 56 | | targets | 12 | 0.166331658 | 0.185501105 | 0 | 29 | 4.19E-04 |
TLR7 and TLR8 | 5 | 5.289740168 | 0.692307692 | 26 | | targets | 14 | 0.142980562 | 0.157942699 | 2638 | 1 | 0.003145391 |
Adrenomedullin receptor AM1; CALCRL/RAMP2 | 3.349485002 | 5.614880391 | 1 | 4 | | targets | 14 | 0.135767022 | 0.150897059 | 109.3333333 | 32 | 9.09E-04 |
Antigen-presenting glycoprotein CD1d | 4.732142857 | 5.466082208 | 0.767857143 | 56 | | targets | 1 | 1 | 1 | 0 | 5 | 0.001317523 |
Glutamate [NMDA] receptor subunit epsilon 4 | 5.547968069 | 5.242543973 | 0.711864407 | 59 | | targets | 12 | 0.173935891 | 0.19923583 | 1992.718636 | 26 | 0.002132763 |
JAK1/JAK2/TYK2 | 6.497272727 | 4.7086311 | 0.545454545 | 66 | | targets | 10 | 0.246279762 | 0.303759651 | 19610.00345 | 33 | 0.007987774 |
JAK2/JAK1 | 5.690100999 | 4.937744165 | 0.6 | 60 | | targets | 10 | 0.246279762 | 0.303759651 | 19610.00345 | 33 | 0.007987774 |
JAK1/TYK2 | 6.684 | 4.889076579 | 0.6 | 20 | | targets | 12 | 0.229383229 | 0.27567687 | 6611.939778 | 33 | 0.005056595 |
CDK9/Cyclin K | 6.218102378 | 5.659808628 | 0.875 | 8 | | targets | 12 | 0.169396111 | 0.196729596 | 3831.76591 | 40 | 0.00462616 |
Solute carrier organic anion transporter family member 4A1 | 4.91733243 | 4.449948138 | 0.666666667 | 3 | | targets | 1 | 1 | 1 | 0 | 27 | 0.001317523 |
Adenosine receptors; A2b & A3 | 6.47 | 5.08466638 | 1 | 2 | | targets | 14 | 0.154745208 | 0.175844309 | 2328.554486 | 32 | 0.00188044 |
Acyl-CoA desaturase | 7.02586541 | 5.072539414 | 0.548183254 | 633 | | targets | 12 | 0.131819992 | 0.145703038 | 1977 | 8 | 0.001149208 |
HSP90 and hnRNPA2/B1 | 4.727442992 | 5.652747829 | 0.625 | 16 | | targets | 10 | 0.220666667 | 0.258735554 | 15075.80882 | 1 | 0.005544019 |
Kinesin-like protein KIF2C | 5.005542975 | 5.433364062 | 0.588235294 | 17 | | targets | 12 | 0.198084979 | 0.230211589 | 583.9761434 | 29 | 0.001738232 |
Kinesin-like protein KIFC1 | 5.2335 | 4.993360014 | 0.6 | 40 | | targets | 12 | 0.165004985 | 0.183609291 | 2.232653154 | 29 | 5.88E-04 |
Diacylglycerol O-acyltransferase 1 | 6.586402261 | 5.150288037 | 0.612227806 | 1194 | | targets | 12 | 0.195395514 | 0.220414438 | 1977.5 | 1 | 0.001392659 |
Eukaryotic initiation factor 4A-I | 6.472331419 | 5.545781191 | 0.73 | 100 | | targets | 12 | 0.166331658 | 0.186945632 | 3951 | 28 | 0.003863727 |
POU domain- class 2- transcription factor 1 | 3.58 | 4.739810024 | 0.666666667 | 3 | | targets | 12 | 0.192218351 | 0.218020298 | 3303.032355 | 40 | 0.001682339 |
H(+)/Cl(-) exchange transporter 3 | 3.5 | 6.188362889 | 0.863636364 | 22 | | targets | 2 | 0.666666667 | 0.75 | 0 | 20 | 0.00101502 |
Diacylglycerol O-acyltransferase 2 | 4.247296819 | 4.932966728 | 0.517241379 | 29 | | targets | 14 | 0.140671483 | 0.150784257 | 0.5 | 1 | 0.001097411 |
Phosphodiesterase 6D | 7.24142426 | 5.544039171 | 0.759259259 | 54 | | targets | 16 | 0.115210581 | 0.122244127 | 0 | 37 | 7.78E-04 |
ADP-ribosylation factor 1 | 5.3025 | 5.121329683 | 0.75 | 4 | | targets | 12 | 0.192778101 | 0.225633111 | 8829.7921 | 29 | 0.004049928 |
ADP-ribosylation factor 6 | 4 | 5.065112048 | 0.666666667 | 3 | | targets | 14 | 0.136663914 | 0.152586156 | 1321 | 14 | 0.001927994 |
Thioredoxin reductase 1 | 4.821116036 | 4.807731088 | 0.636363636 | 11 | | targets | 10 | 0.175132275 | 0.199816573 | 4169.538365 | 21 | 0.002866673 |
Non-specific lipid-transfer protein | 6.245 | 5.673095236 | 1 | 2 | | targets | 16 | 0.086717317 | 0.092853096 | 0 | 8 | 5.86E-04 |
Sodium/myo-inositol cotransporter 2 | 5.433333333 | 5.068526169 | 0.666666667 | 3 | | targets | 1 | 1 | 1 | 0 | 6 | 0.001317523 |
Tryptophan 5-hydroxylase 2 | 5.104285714 | 5.343966203 | 0.714285714 | 7 | | targets | 1 | 1 | 1 | 0 | 30 | 0.001317523 |
Gastric inhibitory polypeptide | 5.645384615 | 5.302819106 | 1 | 13 | | targets | 14 | 0.135822733 | 0.151904109 | 990 | 32 | 0.001552511 |
Cyclin T1 | 10.75049651 | 5.673121825 | 0.830028329 | 353 | | targets | 12 | 0.169396111 | 0.196729596 | 3831.76591 | 40 | 0.00462616 |
Matrix metalloproteinase-25 | 6.880205999 | 4.843590119 | 0.6 | 10 | | targets | 12 | 0.195626478 | 0.220364085 | 2331.541358 | 1 | 9.43E-04 |
Secreted frizzled-related protein 1 | 6.378074845 | 5.119915943 | 0.54679803 | 203 | | targets | 1 | 1 | 1 | 1 | 31 | 0.001922529 |
Matrix metalloproteinase-24 | 3.720411998 | 4.758891763 | 0.6 | 5 | | targets | 14 | 0.141091219 | 0.151323748 | 0 | 1 | 6.48E-04 |
Elongation of very long chain fatty acids protein 6 | 6.395342466 | 5.084623577 | 0.54109589 | 146 | | targets | 12 | 0.132030315 | 0.146609383 | 4585 | 8 | 9.60E-04 |
Elongation of very long chain fatty acids protein 3 | 6.535 | 5.308405821 | 0.785714286 | 14 | | targets | 14 | 0.104779994 | 0.115220685 | 657.6666667 | 8 | 0.001332442 |
Elongation of very long chain fatty acids protein 2 | 5 | 5.199818713 | 0.666666667 | 3 | | targets | 14 | 0.104779994 | 0.115220685 | 657.6666667 | 8 | 0.001332442 |
Elongation of very long chain fatty acids protein 5 | 5 | 5.199818713 | 0.666666667 | 3 | | targets | 14 | 0.104779994 | 0.115220685 | 657.6666667 | 8 | 0.001332442 |
Pituitary adenylate cyclase-activating polypeptide | 9.76 | 5.800279842 | 1 | 2 | | targets | 14 | 0.135822733 | 0.151904109 | 990 | 32 | 0.001552511 |
Kinesin-1 heavy chain | 5.263234588 | 5.790638208 | 0.769230769 | 13 | | targets | 12 | 0.167340748 | 0.190957155 | 1734.137756 | 29 | 0.001581655 |
Bcl-2-like protein 11 | 5.332851208 | 4.586691635 | 0.75 | 8 | | targets | 12 | 0.167935058 | 0.189083215 | 2720.19582 | 33 | 0.002941209 |
Glutathione transferase omega 1 | 7.025803574 | 5.103000563 | 0.636363636 | 11 | | targets | 12 | 0.160757649 | 0.177325314 | 2637 | 1 | 0.00232595 |
Kinetochore protein NDC80 homolog | 4.307692308 | 5.221002827 | 0.538461538 | 13 | | targets | 12 | 0.193002915 | 0.219517085 | 161.9764171 | 29 | 0.001126485 |
Kallikrein 8 | 3.5 | 5.294000043 | 0.75 | 4 | | targets | 1 | 1 | 1 | 0 | 3 | 0.001317523 |
Acyl-protein thioesterase 2 | 5.552380952 | 4.96361265 | 0.619047619 | 21 | | targets | 1 | 1 | 1 | 0 | 7 | 0.001317523 |
Acyl-protein thioesterase 1 | 5.593869948 | 4.939835276 | 0.583333333 | 24 | | targets | 1 | 1 | 1 | 0 | 2 | 0.001317523 |
Nucleophosmin | 4.161 | 5.02323753 | 0.7 | 10 | | targets | 11 | 0.154168607 | 0.169225923 | 1980 | 41 | 0.002204287 |
Proline-rich AKT1 substrate 1 | 5.75 | 5.435002236 | 0.75 | 4 | | targets | 12 | 0.164349553 | 0.181782107 | 2638 | 26 | 0.002912837 |
Kinesin-like protein KIF3C | 2 | 6.023732924 | 1 | 2 | | targets | 12 | 0.166666667 | 0.188899897 | 19.62451973 | 29 | 9.95E-04 |
PPAR delta/gamma | 5 | 6.233155052 | 1 | 4 | | targets | 10 | 0.175876727 | 0.20528581 | 3562.284172 | 21 | 0.002257288 |
CCR5/mu opioid receptor complex | 5 | 5.39866765 | 1 | 2 | | targets | 12 | 0.197966507 | 0.228209479 | 5588.705601 | 34 | 0.003087565 |
AMPK alpha2/beta1/gamma1 | 5.438702854 | 5.054466178 | 0.625 | 72 | | targets | 10 | 0.199157641 | 0.229887186 | 1573.882379 | 21 | 0.001835276 |
3-beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type II | 5.11 | 5.214286662 | 0.666666667 | 3 | | targets | 1 | 1 | 1 | 3 | 35 | 0.002527534 |
Stearoyl-CoA desaturase 5 | 5.108749549 | 5.008468464 | 0.590909091 | 22 | | targets | 14 | 0.104416404 | 0.111561139 | 0 | 8 | 7.56E-04 |
Ubiquitin carboxyl-terminal hydrolase 14 | 5.366666667 | 4.536590504 | 0.666666667 | 3 | | targets | 12 | 0.194248826 | 0.217960954 | 0 | 24 | 4.48E-04 |
Matrix metalloproteinase-20 | 5.885569583 | 5.340698386 | 0.857142857 | 7 | | targets | 14 | 0.142980562 | 0.15653283 | 356.8229837 | 1 | 0.001434901 |
Neuropathy target esterase | 4.25 | 5.485995242 | 0.75 | 4 | | targets | 1 | 1 | 1 | 0 | 4 | 0.001317523 |
S-formylglutathione hydrolase | 4.25 | 5.485995242 | 0.75 | 4 | | targets | 14 | 0.121735932 | 0.128734181 | 0 | 1 | 7.70E-04 |
Calcium-independent phospholipase A2-gamma | 4.25 | 5.485995242 | 0.75 | 4 | | targets | 16 | 0.1150504 | 0.123523034 | 0.25 | 13 | 7.52E-04 |
Acyl-coenzyme A thioesterase 2- mitochondrial | 4.25 | 5.485995242 | 0.75 | 4 | | targets | 2 | 0.666666667 | 0.75 | 0 | 36 | 0.00101502 |
Acyl-coenzyme A thioesterase 1 | 4.25 | 5.485995242 | 0.75 | 4 | | targets | 2 | 0.666666667 | 0.75 | 0 | 36 | 0.00101502 |
Lysosomal thioesterase PPT2 | 4.25 | 5.485995242 | 0.75 | 4 | | targets | 14 | 0.104416404 | 0.111561139 | 0 | 8 | 7.56E-04 |
Pantothenate kinase 1 | 5.207389702 | 5.016461425 | 0.64516129 | 31 | | targets | 2 | 0.666666667 | 0.75 | 0 | 0 | 0.00101502 |
Pantothenate kinase 3 | 5.094726134 | 4.936296891 | 0.536585366 | 41 | | targets | 2 | 0.666666667 | 0.75 | 0 | 0 | 0.00101502 |
EZH2/SUZ12/EED/RBBP7/RBBP4 | 7.66 | 5.652422263 | 0.8 | 55 | | targets | 9 | 0.221552878 | 0.264191603 | 10365.99526 | 41 | 0.005222536 |
Transcription initiation factor TFIID subunit 1 | 4.805555556 | 5.022197128 | 0.666666667 | 9 | | targets | 10 | 0.179209529 | 0.210300676 | 3038.706436 | 40 | 0.00288027 |
Coagulation factor X/antithrombin III | 4.584288685 | 5.85201298 | 0.961538462 | 52 | | targets | 14 | 0.152675277 | 0.171951312 | 2370.361429 | 34 | 0.003194133 |
ERO1-like protein alpha | 4.61054802 | 4.888205185 | 0.583333333 | 12 | | targets | 12 | 0.139251157 | 0.151484907 | 123.8562439 | 21 | 9.83E-04 |
Receptor-type tyrosine-protein phosphatase S | 5.260522019 | 5.053942105 | 0.576923077 | 26 | | targets | 14 | 0.129549902 | 0.141713293 | 1321 | 26 | 0.001740396 |
PI3K p110 beta/p85 alpha | 6.75166784 | 5.383817356 | 0.727272727 | 44 | | targets | 12 | 0.235085227 | 0.301092278 | 15261.09251 | 14 | 0.010226283 |
Proteasome subunit beta type-9 | 5.436341463 | 4.99523368 | 0.536585366 | 41 | | targets | 10 | 0.245003701 | 0.317102455 | 17613.25659 | 37 | 0.014244876 |
Nuclear receptor subfamily 1 group D member 2 | 5.229230769 | 4.865621476 | 0.615384615 | 13 | | targets | 12 | 0.132188498 | 0.145348173 | 0 | 21 | 5.78E-04 |
Protein-arginine deiminase type-6 | 5.086323335 | 5.053819737 | 0.666666667 | 6 | | targets | 14 | 0.130726698 | 0.138841404 | 0 | 33 | 6.98E-04 |
Ubiquitin carboxyl-terminal hydrolase 4 | 5.273333333 | 5.182067439 | 0.666666667 | 3 | | targets | 12 | 0.194591417 | 0.220982102 | 625.0527433 | 38 | 0.001547166 |
Amylin receptor AMY1- CALCR/RAMP1 | 9.19 | 5.469030971 | 1 | 2 | | targets | 14 | 0.135767022 | 0.150897059 | 109.3333333 | 32 | 9.09E-04 |
Amylin receptor AMY3; CALCR/RAMP3 | 5.96 | 5.751210682 | 1 | 2 | | targets | 14 | 0.135767022 | 0.150897059 | 109.3333333 | 32 | 9.09E-04 |
Adrenomedullin receptor- AM2; CALCRL/RAMP3 | 6.23 | 5.609453598 | 1 | 2 | | targets | 14 | 0.135767022 | 0.150897059 | 109.3333333 | 32 | 9.09E-04 |
ATP-sensitive inward rectifier potassium channel 10 | 5 | 5.429880969 | 0.6 | 5 | | targets | 2 | 0.8 | 0.875 | 3.5 | 39 | 0.00193729 |
Presenilin 2 | 8.255 | 5.422886477 | 0.625 | 8 | | targets | 10 | 0.170971074 | 0.193823431 | 4812.935521 | 41 | 0.004695636 |
Transcription initiation factor TFIID subunit 1-like | 5.763333333 | 5.687167207 | 1 | 3 | | targets | 10 | 0.179209529 | 0.210300676 | 3038.706436 | 40 | 0.00288027 |
E3 ubiquitin-protein ligase TRIM33 | 4.8 | 5.465002171 | 1 | 2 | | targets | 12 | 0.139368421 | 0.151560273 | 0 | 41 | 6.23E-04 |
Bromodomain and WD repeat-containing protein 1 | 4.5 | 5.465002171 | 1 | 2 | | targets | 12 | 0.176816239 | 0.196805125 | 1320 | 33 | 9.11E-04 |
Complement factor D | 6.824793814 | 5.257900093 | 0.636597938 | 776 | | targets | 12 | 0.198084979 | 0.223710726 | 928.0021902 | 41 | 0.001237566 |
EZH1/SUZ12/EED/AEBP2/RBBP4 complex | 5.305 | 4.838889237 | 0.75 | 20 | | targets | 10 | 0.19210679 | 0.231367789 | 3133.998462 | 41 | 0.004465896 |
C-C chemokine receptor-like 2 | 6.890320909 | 5.121754811 | 0.681818182 | 176 | | targets | 14 | 0.14193825 | 0.152034513 | 0 | 34 | 6.59E-04 |
Alpha-1-6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 6.978852155 | 4.971958714 | 0.537313433 | 67 | | targets | 1 | 1 | 1 | 0 | 42 | 0.001317523 |
DNMT3A2/3L complex | 4.417142857 | 4.914333804 | 0.714285714 | 21 | | targets | 10 | 0.179306609 | 0.201849854 | 762.6980752 | 41 | 0.001081903 |
Beta-1-4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase | 6.589125121 | 5.636982641 | 0.870967742 | 31 | | targets | 1 | 1 | 1 | 0 | 43 | 0.001317523 |
Alpha-1-3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 6.173104445 | 5.212964223 | 0.666666667 | 9 | | targets | 1 | 1 | 1 | 0 | 44 | 0.001317523 |
Toll-like receptor 4/MD-2 | 4.903225806 | 5.49171516 | 0.983870968 | 62 | | targets | 12 | 0.181768259 | 0.212680539 | 10330.79256 | 38 | 0.005917277 |
Muscle glycogen synthase | 6.372004837 | 5.298839983 | 0.663636364 | 110 | | targets | 1 | 1 | 1 | 10 | 45 | 0.003737545 |
TAK1/TAB1 | 5.988923097 | 5.220922629 | 0.620689655 | 174 | | targets | 12 | 0.211772233 | 0.25167313 | 11482.47466 | 37 | 0.00532433 |
CDK2/CDK4 | 5 | 7.271944444 | 1 | 12 | | targets | 9 | 0.233757062 | 0.284677265 | 15015.4698 | 24 | 0.006062838 |
AMPK alpha1/beta2/gamma1 | 5 | 5.377626184 | 1 | 3 | | targets | 10 | 0.199157641 | 0.229887186 | 1573.882379 | 21 | 0.001835276 |
AMPK alpha1/beta1/gamma3 | 5 | 5.377626184 | 1 | 3 | | targets | 10 | 0.197494033 | 0.225229583 | 832.3646283 | 21 | 0.001405796 |
AMPK alpha1/beta1/gamma2 | 5 | 5.377626184 | 1 | 3 | | targets | 10 | 0.199157641 | 0.229887186 | 1573.882379 | 21 | 0.001835276 |
G protein-activated inward rectifier potassium channel 2 | 2 | 4.829756694 | 0.666666667 | 12 | | targets | 3 | 0.571428571 | 0.708333333 | 0.5 | 39 | 0.001302761 |
AMPK alpha1/alpha2 | 4.75153332 | 5.477404581 | 0.916666667 | 24 | | targets | 10 | 0.199157641 | 0.229887186 | 1573.882379 | 21 | 0.001835276 |
PI4KA/PI4KAP2 | 4.789738888 | 5.495903149 | 0.916666667 | 24 | | targets | 14 | 0.139368421 | 0.151032913 | 661 | 29 | 0.001271622 |
p38 delta/gamma | 4.779057542 | 5.789162001 | 0.916666667 | 24 | | targets | 12 | 0.18700565 | 0.211887487 | 3311.089957 | 21 | 0.002363932 |
Casein kinase I delta/epsilon | 4.939719454 | 5.469904978 | 0.833333333 | 24 | | targets | 9 | 0.192665891 | 0.221817005 | 4807.736865 | 24 | 0.002839949 |
IKK epsilon/TBK1 | 4.736912671 | 5.477404581 | 0.916666667 | 24 | | targets | 14 | 0.134171058 | 0.151867216 | 4606 | 38 | 0.005025662 |
Ionotropic glutamate receptor NMDA 1/2C | 4.485166916 | 5.30790619 | 1 | 4 | | targets | 12 | 0.174210526 | 0.200821933 | 2931.387588 | 26 | 0.002536772 |
Bromodomain-containing protein 7 | 5.451554654 | 4.94492536 | 0.666666667 | 6 | | targets | 10 | 0.159826171 | 0.171291301 | 0 | 41 | 4.80E-04 |
Nicotinic acetylcholine receptor alpha6/alpha3/beta4 | 7.3425 | 6.669065527 | 1 | 12 | | targets | 12 | 0.195395514 | 0.221043844 | 1980 | 1 | 0.002175749 |
c-Myc/Max | 4.406666667 | 5.305535782 | 0.666666667 | 6 | | targets | 10 | 0.242668622 | 0.281570398 | 20440.84179 | 41 | 0.003792653 |
Polymerase basic protein 2 | 7.158862667 | 4.945076255 | 0.533333333 | 30 | | targets | 1 | 1 | 1 | 105 | 46 | 0.009787599 |
Neurogenic locus notch homolog protein 3 | 8.0295 | 4.816949045 | 0.55 | 20 | | targets | 12 | 0.160212972 | 0.177066958 | 2820.392024 | 41 | 0.003282149 |
Kininogen-1 | 8.066290323 | 6.001328081 | 0.830645161 | 124 | | targets | 12 | 0.192778101 | 0.221541973 | 5860.126062 | 34 | 0.002386282 |
Acetyl-coenzyme A transporter 1 | 8.709470199 | 5.246358395 | 0.688741722 | 151 | | targets | 1 | 1 | 1 | 0 | 47 | 0.001317523 |
Aurora kinase B/Inner centromere protein | 8.040909091 | 5.182064058 | 0.545454545 | 22 | | targets | 10 | 0.204194941 | 0.23610152 | 1957.321945 | 29 | 0.001909925 |
PI3-kinase class I | 6.352121212 | 5.375741631 | 0.697552448 | 3432 | | targets | 12 | 0.23525231 | 0.302099327 | 16010.0907 | 14 | 0.010502416 |