| Apolipoprotein A-I | ABC transporters in lipid homeostasis | 1 | 5 | 5.9178191800746 | 1 | 1 | 1 | 5 | 5.9178191800746 | 1 |
| Non-specific lipid-transfer protein | alpha-linolenic acid (ALA) metabolism | 1 | 6.245 | 5.6730952357059 | 2 | 1 | 0.51167574824291 | 4.5017401475727 | 4.8162408414733 | 624 |
| Elongation of very long chain fatty acids protein 3 | alpha-linolenic acid (ALA) metabolism | 0.78571428571429 | 6.535 | 5.3084058210886 | 14 | 10 | 0.51167574824291 | 4.5017401475727 | 4.8162408414733 | 624 |
| Elongation of very long chain fatty acids protein 2 | alpha-linolenic acid (ALA) metabolism | 0.66666666666667 | 5 | 5.1998187132522 | 3 | 3 | 0.51167574824291 | 4.5017401475727 | 4.8162408414733 | 624 |
| AMPK alpha1/beta2/gamma1 | AMPK inhibits chREBP transcriptional activation activity | 1 | 5 | 5.377626183921 | 3 | 1 | 0.54568534691047 | 5.1171844879696 | 4.7108581414292 | 18809 |
| AMPK alpha1/alpha2 | AMPK inhibits chREBP transcriptional activation activity | 0.91666666666667 | 4.7515333198674 | 5.4774045809888 | 24 | 12 | 0.54568534691047 | 5.1171844879696 | 4.7108581414292 | 18809 |
| AMPK alpha2/beta1/gamma1 | AMPK inhibits chREBP transcriptional activation activity | 0.625 | 5.438702854259 | 5.0544661779205 | 72 | 17 | 0.54568534691047 | 5.1171844879696 | 4.7108581414292 | 18809 |
| Adiponectin receptor protein 2 | AMPK inhibits chREBP transcriptional activation activity | 1 | 5.51 | 5.1364239305289 | 1 | 1 | 0.54568534691047 | 5.1171844879696 | 4.7108581414292 | 18809 |
| Adiponectin receptor protein 1 | AMPK inhibits chREBP transcriptional activation activity | 1 | 5.74 | 5.1364239305289 | 1 | 1 | 0.54568534691047 | 5.1171844879696 | 4.7108581414292 | 18809 |
| AMPK alpha1/beta1/gamma2 | AMPK inhibits chREBP transcriptional activation activity | 1 | 5 | 5.377626183921 | 3 | 1 | 0.54568534691047 | 5.1171844879696 | 4.7108581414292 | 18809 |
| 26S proteosome | APC/C:Cdc20 mediated degradation of Securin | 0.67188240872451 | 5.7537684819849 | 5.902813128367 | 2109 | 58 | 0.58219255042243 | 5.6102511489448 | 5.5705767988487 | 79596 |
| Proteasome subunit beta type-9 | APC/C:Cdc20 mediated degradation of Securin | 0.53658536585366 | 5.4363414634146 | 4.9952336804744 | 41 | 23 | 0.58219255042243 | 5.6102511489448 | 5.5705767988487 | 79596 |
| 26S proteosome | APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | 0.67188240872451 | 5.7537684819849 | 5.902813128367 | 2109 | 58 | 0.56544728669534 | 5.6383251322085 | 5.4901389752586 | 116560 |
| Proteasome subunit beta type-9 | APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | 0.53658536585366 | 5.4363414634146 | 4.9952336804744 | 41 | 23 | 0.56544728669534 | 5.6383251322085 | 5.4901389752586 | 116560 |
| Aurora kinase B/Inner centromere protein | APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | 0.54545454545454 | 8.0409090909091 | 5.1820640577436 | 22 | 10 | 0.56544728669534 | 5.6383251322085 | 5.4901389752586 | 116560 |
| 26S proteosome | Asymmetric localization of PCP proteins | 0.67188240872451 | 5.7537684819849 | 5.902813128367 | 2109 | 58 | 0.5616519307489 | 5.5629562577956 | 5.499476846754 | 79620 |
| Proteasome subunit beta type-9 | Asymmetric localization of PCP proteins | 0.53658536585366 | 5.4363414634146 | 4.9952336804744 | 41 | 23 | 0.5616519307489 | 5.5629562577956 | 5.499476846754 | 79620 |
| 26S proteosome | AUF1 (hnRNP D0) binds and destabilizes mRNA | 0.67188240872451 | 5.7537684819849 | 5.902813128367 | 2109 | 58 | 0.5468167991935 | 5.5098743637718 | 5.4341350788331 | 84067 |
| Proteasome subunit beta type-9 | AUF1 (hnRNP D0) binds and destabilizes mRNA | 0.53658536585366 | 5.4363414634146 | 4.9952336804744 | 41 | 23 | 0.5468167991935 | 5.5098743637718 | 5.4341350788331 | 84067 |
| 26S proteosome | Autodegradation of Cdh1 by Cdh1:APC/C | 0.67188240872451 | 5.7537684819849 | 5.902813128367 | 2109 | 58 | 0.57820633449789 | 5.6038726008096 | 5.555810739759 | 75378 |
| Proteasome subunit beta type-9 | Autodegradation of Cdh1 by Cdh1:APC/C | 0.53658536585366 | 5.4363414634146 | 4.9952336804744 | 41 | 23 | 0.57820633449789 | 5.6038726008096 | 5.555810739759 | 75378 |
| 26S proteosome | Autodegradation of the E3 ubiquitin ligase COP1 | 0.67188240872451 | 5.7537684819849 | 5.902813128367 | 2109 | 58 | 0.54147509539101 | 5.5176029982376 | 5.453207182257 | 132379 |
| Proteasome subunit beta type-9 | Autodegradation of the E3 ubiquitin ligase COP1 | 0.53658536585366 | 5.4363414634146 | 4.9952336804744 | 41 | 23 | 0.54147509539101 | 5.5176029982376 | 5.453207182257 | 132379 |
| Amylin receptor AMY1- CALCR/RAMP1 | Calcitonin-like ligand receptors | 1 | 9.19 | 5.4690309706589 | 2 | 1 | 0.67176671693661 | 6.0312440488392 | 4.9415954173055 | 3871 |
| Calcitonin-gene-related peptide receptor- CALCRL/RAMP1 | Calcitonin-like ligand receptors | 0.75210084033613 | 7.5815778412324 | 5.6030854863775 | 238 | 79 | 0.67176671693661 | 6.0312440488392 | 4.9415954173055 | 3871 |
| Adrenomedullin receptor AM1; CALCRL/RAMP2 | Calcitonin-like ligand receptors | 1 | 3.349485002168 | 5.614880391294 | 4 | 2 | 0.67176671693661 | 6.0312440488392 | 4.9415954173055 | 3871 |
| Amylin receptor AMY3; CALCR/RAMP3 | Calcitonin-like ligand receptors | 1 | 5.96 | 5.7512106817086 | 2 | 1 | 0.67176671693661 | 6.0312440488392 | 4.9415954173055 | 3871 |
| Adrenomedullin receptor- AM2; CALCRL/RAMP3 | Calcitonin-like ligand receptors | 1 | 6.23 | 5.6094535984695 | 2 | 1 | 0.67176671693661 | 6.0312440488392 | 4.9415954173055 | 3871 |
| Calcitonin gene-related peptide 1 | Calcitonin-like ligand receptors | 0.57241379310345 | 6.1718257610381 | 4.6376436999715 | 145 | 77 | 0.67176671693661 | 6.0312440488392 | 4.9415954173055 | 3871 |
| Tubulin | Carboxyterminal post-translational modifications of tubulin | 0.72316032705297 | 5.1959502543901 | 5.7192183186131 | 33756 | 2146 | 0.69200486440469 | 5.3770718418628 | 5.6761460918886 | 945566 |
| Tubulin beta-2 chain | Carboxyterminal post-translational modifications of tubulin | 0.54166666666667 | 5.3697845939063 | 5.2542384943368 | 24 | 17 | 0.69200486440469 | 5.3770718418628 | 5.6761460918886 | 945566 |
| Tubulin beta-3 chain | Carboxyterminal post-translational modifications of tubulin | 0.77777777777778 | 7.9022222222222 | 6.7425056150832 | 9 | 7 | 0.69200486440469 | 5.3770718418628 | 5.6761460918886 | 945566 |
| Tubulin beta-1 chain | Carboxyterminal post-translational modifications of tubulin | 0.6038961038961 | 5.3294885216762 | 5.3840182759259 | 154 | 143 | 0.69200486440469 | 5.3770718418628 | 5.6761460918886 | 945566 |
| 26S proteosome | Cdc20:Phospho-APC/C mediated degradation of Cyclin A | 0.67188240872451 | 5.7537684819849 | 5.902813128367 | 2109 | 58 | 0.56772622536244 | 5.6209548694022 | 5.4437285267733 | 99960 |
| CDK1/Cyclin A | Cdc20:Phospho-APC/C mediated degradation of Cyclin A | 0.85714285714286 | 6.2061004678591 | 5.7827915249492 | 14 | 6 | 0.56772622536244 | 5.6209548694022 | 5.4437285267733 | 99960 |
| CDK1/Cyclin E | Cdc20:Phospho-APC/C mediated degradation of Cyclin A | 0.66666666666667 | 5.5244149856255 | 5.9608462091247 | 6 | 3 | 0.56772622536244 | 5.6209548694022 | 5.4437285267733 | 99960 |
| Proteasome subunit beta type-9 | Cdc20:Phospho-APC/C mediated degradation of Cyclin A | 0.53658536585366 | 5.4363414634146 | 4.9952336804744 | 41 | 23 | 0.56772622536244 | 5.6209548694022 | 5.4437285267733 | 99960 |
| CDK2/Cyclin A1 | Cdc20:Phospho-APC/C mediated degradation of Cyclin A | 1 | 6.3750775913315 | 5.9652604435778 | 12 | 5 | 0.56772622536244 | 5.6209548694022 | 5.4437285267733 | 99960 |
| 26S proteosome | CDK-mediated phosphorylation and removal of Cdc6 | 0.67188240872451 | 5.7537684819849 | 5.902813128367 | 2109 | 58 | 0.5613307999749 | 5.5485706853836 | 5.485924720812 | 95730 |
| CDK2/Cyclin A1 | CDK-mediated phosphorylation and removal of Cdc6 | 1 | 6.3750775913315 | 5.9652604435778 | 12 | 5 | 0.5613307999749 | 5.5485706853836 | 5.485924720812 | 95730 |
| CDK2/CDK4 | CDK-mediated phosphorylation and removal of Cdc6 | 1 | 5 | 7.2719444444444 | 12 | 6 | 0.5613307999749 | 5.5485706853836 | 5.485924720812 | 95730 |
| Proteasome subunit beta type-9 | CDK-mediated phosphorylation and removal of Cdc6 | 0.53658536585366 | 5.4363414634146 | 4.9952336804744 | 41 | 23 | 0.5613307999749 | 5.5485706853836 | 5.485924720812 | 95730 |
| 26S proteosome | CDT1 association with the CDC6:ORC:origin complex | 0.67188240872451 | 5.7537684819849 | 5.902813128367 | 2109 | 58 | 0.56229953391194 | 5.5274432318558 | 5.5257094430321 | 207606 |
| Proteasome subunit beta type-9 | CDT1 association with the CDC6:ORC:origin complex | 0.53658536585366 | 5.4363414634146 | 4.9952336804744 | 41 | 23 | 0.56229953391194 | 5.5274432318558 | 5.5257094430321 | 207606 |
| Tubulin | Cilium Assembly | 0.72316032705297 | 5.1959502543901 | 5.7192183186131 | 33756 | 2146 | 0.6702118836517 | 5.4298865879633 | 5.5939708344286 | 515610 |
| Tubulin beta-2 chain | Cilium Assembly | 0.54166666666667 | 5.3697845939063 | 5.2542384943368 | 24 | 17 | 0.6702118836517 | 5.4298865879633 | 5.5939708344286 | 515610 |
| Tubulin beta-3 chain | Cilium Assembly | 0.77777777777778 | 7.9022222222222 | 6.7425056150832 | 9 | 7 | 0.6702118836517 | 5.4298865879633 | 5.5939708344286 | 515610 |
| Tubulin beta-1 chain | Cilium Assembly | 0.6038961038961 | 5.3294885216762 | 5.3840182759259 | 154 | 143 | 0.6702118836517 | 5.4298865879633 | 5.5939708344286 | 515610 |
| Succinate dehydrogenase [ubiquinone] flavoprotein subunit- mitochondrial | Citric acid cycle (TCA cycle) | 1 | 5 | 5.6760349523221 | 1 | 1 | 0.54954954954955 | 5.0352735752528 | 4.6813845969403 | 112 |
| ADP-ribosylation factor 1 | Clathrin derived vesicle budding | 0.75 | 5.3025 | 5.1213296827909 | 4 | 2 | 0.75 | 5.3025 | 5.1213296827909 | 4 |
| Pantothenate kinase 1 | Coenzyme A biosynthesis | 0.64516129032258 | 5.2073897022681 | 5.0164614254804 | 31 | 30 | 0.72724888539208 | 5.780705278712 | 5.2455067498676 | 73 |
| Pantothenate kinase 2- mitochondrial | Coenzyme A biosynthesis | 1 | 7.04 | 5.7837619333982 | 1 | 1 | 0.72724888539208 | 5.780705278712 | 5.2455067498676 | 73 |
| Pantothenate kinase 3 | Coenzyme A biosynthesis | 0.53658536585366 | 5.0947261338679 | 4.9362968907243 | 41 | 37 | 0.72724888539208 | 5.780705278712 | 5.2455067498676 | 73 |
| Kinesin-like protein KIF3C | COPI-dependent Golgi-to-ER retrograde traffic | 1 | 2 | 6.0237329237034 | 2 | 1 | 0.51209653574644 | 4.3826205477984 | 5.1262601807862 | 476618 |
| Tubulin | COPI-dependent Golgi-to-ER retrograde traffic | 0.72316032705297 | 5.1959502543901 | 5.7192183186131 | 33756 | 2146 | 0.51209653574644 | 4.3826205477984 | 5.1262601807862 | 476618 |
| Kinesin-1 heavy chain | COPI-dependent Golgi-to-ER retrograde traffic | 0.76923076923077 | 5.263234588108 | 5.7906382081001 | 13 | 12 | 0.51209653574644 | 4.3826205477984 | 5.1262601807862 | 476618 |
| Tubulin beta-2 chain | COPI-dependent Golgi-to-ER retrograde traffic | 0.54166666666667 | 5.3697845939063 | 5.2542384943368 | 24 | 17 | 0.51209653574644 | 4.3826205477984 | 5.1262601807862 | 476618 |
| ADP-ribosylation factor 1 | COPI-dependent Golgi-to-ER retrograde traffic | 0.75 | 5.3025 | 5.1213296827909 | 4 | 2 | 0.51209653574644 | 4.3826205477984 | 5.1262601807862 | 476618 |
| Tubulin beta-3 chain | COPI-dependent Golgi-to-ER retrograde traffic | 0.77777777777778 | 7.9022222222222 | 6.7425056150832 | 9 | 7 | 0.51209653574644 | 4.3826205477984 | 5.1262601807862 | 476618 |
| Kinesin-like protein KIF2C | COPI-dependent Golgi-to-ER retrograde traffic | 0.58823529411765 | 5.0055429749974 | 5.4333640617631 | 17 | 15 | 0.51209653574644 | 4.3826205477984 | 5.1262601807862 | 476618 |
| Tubulin beta-1 chain | COPI-dependent Golgi-to-ER retrograde traffic | 0.6038961038961 | 5.3294885216762 | 5.3840182759259 | 154 | 143 | 0.51209653574644 | 4.3826205477984 | 5.1262601807862 | 476618 |
| Kinesin-like protein KIF9 | COPI-dependent Golgi-to-ER retrograde traffic | 1 | 2 | 5.576930706625 | 1 | 1 | 0.51209653574644 | 4.3826205477984 | 5.1262601807862 | 476618 |
| Tubulin | COPI-independent Golgi-to-ER retrograde traffic | 0.72316032705297 | 5.1959502543901 | 5.7192183186131 | 33756 | 2146 | 0.59051722467106 | 5.0841043267243 | 5.4247956598705 | 473552 |
| Tubulin beta-2 chain | COPI-independent Golgi-to-ER retrograde traffic | 0.54166666666667 | 5.3697845939063 | 5.2542384943368 | 24 | 17 | 0.59051722467106 | 5.0841043267243 | 5.4247956598705 | 473552 |
| Tubulin beta-3 chain | COPI-independent Golgi-to-ER retrograde traffic | 0.77777777777778 | 7.9022222222222 | 6.7425056150832 | 9 | 7 | 0.59051722467106 | 5.0841043267243 | 5.4247956598705 | 473552 |
| Tubulin beta-1 chain | COPI-independent Golgi-to-ER retrograde traffic | 0.6038961038961 | 5.3294885216762 | 5.3840182759259 | 154 | 143 | 0.59051722467106 | 5.0841043267243 | 5.4247956598705 | 473552 |
| Tubulin | COPI-mediated anterograde transport | 0.72316032705297 | 5.1959502543901 | 5.7192183186131 | 33756 | 2146 | 0.60012038264642 | 5.080759834506 | 5.4036945946742 | 472871 |
| Tubulin beta-2 chain | COPI-mediated anterograde transport | 0.54166666666667 | 5.3697845939063 | 5.2542384943368 | 24 | 17 | 0.60012038264642 | 5.080759834506 | 5.4036945946742 | 472871 |
| ADP-ribosylation factor 1 | COPI-mediated anterograde transport | 0.75 | 5.3025 | 5.1213296827909 | 4 | 2 | 0.60012038264642 | 5.080759834506 | 5.4036945946742 | 472871 |
| Tubulin beta-3 chain | COPI-mediated anterograde transport | 0.77777777777778 | 7.9022222222222 | 6.7425056150832 | 9 | 7 | 0.60012038264642 | 5.080759834506 | 5.4036945946742 | 472871 |
| Tubulin beta-1 chain | COPI-mediated anterograde transport | 0.6038961038961 | 5.3294885216762 | 5.3840182759259 | 154 | 143 | 0.60012038264642 | 5.080759834506 | 5.4036945946742 | 472871 |
| PI3-kinase class I | Costimulation by the CD28 family | 0.69755244755245 | 6.3521212121212 | 5.3757416305446 | 3432 | 427 | 0.51468330774287 | 6.0977009709964 | 4.9304252729197 | 23428 |
| PI3-kinase p85-alpha subunit | Costimulation by the CD28 family | 0.58333333333333 | 5.5716666666667 | 4.9949744849658 | 12 | 11 | 0.51468330774287 | 6.0977009709964 | 4.9304252729197 | 23428 |
| PI3K p110 beta/p85 alpha | Costimulation by the CD28 family | 0.72727272727273 | 6.7516678401512 | 5.383817355816 | 44 | 22 | 0.51468330774287 | 6.0977009709964 | 4.9304252729197 | 23428 |
| 26S proteosome | Cross-presentation of soluble exogenous antigens (endosomes) | 0.67188240872451 | 5.7537684819849 | 5.902813128367 | 2109 | 58 | 0.52776878343449 | 5.4152468122832 | 5.3257670966931 | 79666 |
| Proteasome subunit beta type-9 | Cross-presentation of soluble exogenous antigens (endosomes) | 0.53658536585366 | 5.4363414634146 | 4.9952336804744 | 41 | 23 | 0.52776878343449 | 5.4152468122832 | 5.3257670966931 | 79666 |
| 26S proteosome | Dectin-1 mediated noncanonical NF-kB signaling | 0.67188240872451 | 5.7537684819849 | 5.902813128367 | 2109 | 58 | 0.5311773970215 | 5.5142786603303 | 5.3468511342935 | 99746 |
| Proteasome subunit beta type-9 | Dectin-1 mediated noncanonical NF-kB signaling | 0.53658536585366 | 5.4363414634146 | 4.9952336804744 | 41 | 23 | 0.5311773970215 | 5.5142786603303 | 5.3468511342935 | 99746 |
| 26S proteosome | Defective CFTR causes cystic fibrosis | 0.67188240872451 | 5.7537684819849 | 5.902813128367 | 2109 | 58 | 0.56591265408076 | 5.5826018278693 | 5.5127590022105 | 80686 |
| Proteasome subunit beta type-9 | Defective CFTR causes cystic fibrosis | 0.53658536585366 | 5.4363414634146 | 4.9952336804744 | 41 | 23 | 0.56591265408076 | 5.5826018278693 | 5.5127590022105 | 80686 |
| Neurogenic locus notch homolog protein 2 | Defective LFNG causes SCDO3 | 1 | 9 | 5.1743475439684 | 1 | 1 | 0.7575 | 8.1221462125472 | 4.975438917953 | 47 |
| Neurogenic locus notch homolog protein 4 | Defective LFNG causes SCDO3 | 1 | 8.52 | 5.1743475439684 | 1 | 1 | 0.7575 | 8.1221462125472 | 4.975438917953 | 47 |
| Neurogenic locus notch homolog protein 3 | Defective LFNG causes SCDO3 | 0.55 | 8.0295 | 4.8169490448885 | 20 | 20 | 0.7575 | 8.1221462125472 | 4.975438917953 | 47 |
| 26S proteosome | Degradation of AXIN | 0.67188240872451 | 5.7537684819849 | 5.902813128367 | 2109 | 58 | 0.52375066439822 | 5.6435208416624 | 5.3574627101998 | 80420 |
| Proteasome subunit beta type-9 | Degradation of AXIN | 0.53658536585366 | 5.4363414634146 | 4.9952336804744 | 41 | 23 | 0.52375066439822 | 5.6435208416624 | 5.3574627101998 | 80420 |
| 26S proteosome | Degradation of DVL | 0.67188240872451 | 5.7537684819849 | 5.902813128367 | 2109 | 58 | 0.55114988628597 | 5.5315617690247 | 5.4763053229506 | 79640 |
| Proteasome subunit beta type-9 | Degradation of DVL | 0.53658536585366 | 5.4363414634146 | 4.9952336804744 | 41 | 23 | 0.55114988628597 | 5.5315617690247 | 5.4763053229506 | 79640 |
| 26S proteosome | Degradation of GLI1 by the proteasome | 0.67188240872451 | 5.7537684819849 | 5.902813128367 | 2109 | 58 | 0.52679903787794 | 5.4485290950052 | 5.3387983737111 | 89908 |
| cAMP-dependent protein kinase- gamma catalytic subunit | Degradation of GLI1 by the proteasome | 0.625 | 4.5041177610417 | 5.11256574157 | 8 | 8 | 0.52679903787794 | 5.4485290950052 | 5.3387983737111 | 89908 |
| Proteasome subunit beta type-9 | Degradation of GLI1 by the proteasome | 0.53658536585366 | 5.4363414634146 | 4.9952336804744 | 41 | 23 | 0.52679903787794 | 5.4485290950052 | 5.3387983737111 | 89908 |
| 26S proteosome | Degradation of GLI2 by the proteasome | 0.67188240872451 | 5.7537684819849 | 5.902813128367 | 2109 | 58 | 0.51662930701804 | 5.4291840708018 | 5.2878064335127 | 98223 |
| Proteasome subunit beta type-9 | Degradation of GLI2 by the proteasome | 0.53658536585366 | 5.4363414634146 | 4.9952336804744 | 41 | 23 | 0.51662930701804 | 5.4291840708018 | 5.2878064335127 | 98223 |
| Nucleophosmin | Deposition of new CENPA-containing nucleosomes at the centromere | 0.7 | 4.161 | 5.0232375304688 | 10 | 4 | 0.57851089588378 | 5.6055150851227 | 5.0292725552566 | 271 |
| EZH2/SUZ12/EED/RBBP7/RBBP4 | Deposition of new CENPA-containing nucleosomes at the centromere | 0.8 | 7.66 | 5.6524222632749 | 55 | 7 | 0.57851089588378 | 5.6055150851227 | 5.0292725552566 | 271 |
| EZH1/SUZ12/EED/AEBP2/RBBP4 complex | Deposition of new CENPA-containing nucleosomes at the centromere | 0.75 | 5.305 | 4.8388892371782 | 20 | 4 | 0.57851089588378 | 5.6055150851227 | 5.0292725552566 | 271 |
| 26S proteosome | FBXL7 down-regulates AURKA during mitotic entry and in early mitosis | 0.67188240872451 | 5.7537684819849 | 5.902813128367 | 2109 | 58 | 0.57841154857175 | 5.6095694018368 | 5.5495363281361 | 85558 |
| Proteasome subunit beta type-9 | FBXL7 down-regulates AURKA during mitotic entry and in early mitosis | 0.53658536585366 | 5.4363414634146 | 4.9952336804744 | 41 | 23 | 0.57841154857175 | 5.6095694018368 | 5.5495363281361 | 85558 |
| Tubulin | Formation of tubulin folding intermediates by CCT/TriC | 0.72316032705297 | 5.1959502543901 | 5.7192183186131 | 33756 | 2146 | 0.70777655000182 | 5.3843030403047 | 5.7331625329572 | 439015 |
| Tubulin beta-2 chain | Formation of tubulin folding intermediates by CCT/TriC | 0.54166666666667 | 5.3697845939063 | 5.2542384943368 | 24 | 17 | 0.70777655000182 | 5.3843030403047 | 5.7331625329572 | 439015 |
| Tubulin beta-3 chain | Formation of tubulin folding intermediates by CCT/TriC | 0.77777777777778 | 7.9022222222222 | 6.7425056150832 | 9 | 7 | 0.70777655000182 | 5.3843030403047 | 5.7331625329572 | 439015 |
| Tubulin beta-1 chain | Formation of tubulin folding intermediates by CCT/TriC | 0.6038961038961 | 5.3294885216762 | 5.3840182759259 | 154 | 143 | 0.70777655000182 | 5.3843030403047 | 5.7331625329572 | 439015 |
| 26S proteosome | G2/M Checkpoints | 0.67188240872451 | 5.7537684819849 | 5.902813128367 | 2109 | 58 | 0.54908549586531 | 5.5331143798414 | 5.4815276930654 | 128851 |
| Proteasome subunit beta type-9 | G2/M Checkpoints | 0.53658536585366 | 5.4363414634146 | 4.9952336804744 | 41 | 23 | 0.54908549586531 | 5.5331143798414 | 5.4815276930654 | 128851 |
| Tubulin | Gap junction assembly | 0.72316032705297 | 5.1959502543901 | 5.7192183186131 | 33756 | 2146 | 0.70868147806365 | 5.3732234646627 | 5.7323422850546 | 472771 |
| Tubulin beta-2 chain | Gap junction assembly | 0.54166666666667 | 5.3697845939063 | 5.2542384943368 | 24 | 17 | 0.70868147806365 | 5.3732234646627 | 5.7323422850546 | 472771 |
| Tubulin beta-3 chain | Gap junction assembly | 0.77777777777778 | 7.9022222222222 | 6.7425056150832 | 9 | 7 | 0.70868147806365 | 5.3732234646627 | 5.7323422850546 | 472771 |
| Tubulin beta-1 chain | Gap junction assembly | 0.6038961038961 | 5.3294885216762 | 5.3840182759259 | 154 | 143 | 0.70868147806365 | 5.3732234646627 | 5.7323422850546 | 472771 |
| Vitamin D3 receptor-interacting protein | Generic Transcription Pathway | 1 | 5.74 | 6.5552828645286 | 1 | 1 | 0.54222972972973 | 4.4962032253592 | 5.0063350323078 | 619 |
| 26S proteosome | GLI3 is processed to GLI3R by the proteasome | 0.67188240872451 | 5.7537684819849 | 5.902813128367 | 2109 | 58 | 0.52408195498575 | 5.4353762388858 | 5.3134009136152 | 98210 |
| cAMP-dependent protein kinase- gamma catalytic subunit | GLI3 is processed to GLI3R by the proteasome | 0.625 | 4.5041177610417 | 5.11256574157 | 8 | 8 | 0.52408195498575 | 5.4353762388858 | 5.3134009136152 | 98210 |
| Proteasome subunit beta type-9 | GLI3 is processed to GLI3R by the proteasome | 0.53658536585366 | 5.4363414634146 | 4.9952336804744 | 41 | 23 | 0.52408195498575 | 5.4353762388858 | 5.3134009136152 | 98210 |
| Muscle glycogen synthase | Glycogen storage disease type 0 (muscle GYS1) | 0.66363636363636 | 6.3720048371326 | 5.298839983388 | 110 | 46 | 0.66363636363636 | 6.3720048371326 | 5.298839983388 | 110 |
| Muscle glycogen synthase | Glycogen storage disease type IV (GBE1) | 0.66363636363636 | 6.3720048371326 | 5.298839983388 | 110 | 46 | 0.66363636363636 | 6.3720048371326 | 5.298839983388 | 110 |
| Muscle glycogen synthase | Glycogen storage disease type XV (GYG1) | 0.66363636363636 | 6.3720048371326 | 5.298839983388 | 110 | 46 | 0.66363636363636 | 6.3720048371326 | 5.298839983388 | 110 |
| Muscle glycogen synthase | Glycogen synthesis | 0.66363636363636 | 6.3720048371326 | 5.298839983388 | 110 | 46 | 0.51931818181818 | 5.1599323401463 | 4.9730722560886 | 118 |
| Apolipoprotein A-I | HDL clearance | 1 | 5 | 5.9178191800746 | 1 | 1 | 1 | 5 | 5.9178191800746 | 1 |
| 26S proteosome | Hedgehog ligand biogenesis | 0.67188240872451 | 5.7537684819849 | 5.902813128367 | 2109 | 58 | 0.56357020932731 | 5.5904243877833 | 5.4992163929793 | 80813 |
| Proteasome subunit beta type-9 | Hedgehog ligand biogenesis | 0.53658536585366 | 5.4363414634146 | 4.9952336804744 | 41 | 23 | 0.56357020932731 | 5.5904243877833 | 5.4992163929793 | 80813 |
| 26S proteosome | Hedgehog 'on' state | 0.67188240872451 | 5.7537684819849 | 5.902813128367 | 2109 | 58 | 0.53605617214167 | 5.5075661266209 | 5.3937302014277 | 82055 |
| Proteasome subunit beta type-9 | Hedgehog 'on' state | 0.53658536585366 | 5.4363414634146 | 4.9952336804744 | 41 | 23 | 0.53605617214167 | 5.5075661266209 | 5.3937302014277 | 82055 |
| 26S proteosome | Hh mutants that don't undergo autocatalytic processing are degraded by ERAD | 0.67188240872451 | 5.7537684819849 | 5.902813128367 | 2109 | 58 | 0.57074572227658 | 5.6023330684792 | 5.5284469144647 | 80412 |
| Proteasome subunit beta type-9 | Hh mutants that don't undergo autocatalytic processing are degraded by ERAD | 0.53658536585366 | 5.4363414634146 | 4.9952336804744 | 41 | 23 | 0.57074572227658 | 5.6023330684792 | 5.5284469144647 | 80412 |
| Cyclin T1 | HIV elongation arrest and recovery | 0.8300283286119 | 10.750496508514 | 5.6731218252674 | 353 | 349 | 0.51931689535494 | 5.9633225594594 | 4.7490295318788 | 4063 |
| CDK9/Cyclin K | HIV elongation arrest and recovery | 0.875 | 6.2181023779453 | 5.6598086280743 | 8 | 3 | 0.51931689535494 | 5.9633225594594 | 4.7490295318788 | 4063 |
| Tubulin | HSP90 chaperone cycle for steroid hormone receptors (SHR) | 0.72316032705297 | 5.1959502543901 | 5.7192183186131 | 33756 | 2146 | 0.52737457499618 | 5.3179169946462 | 5.1275161362286 | 520005 |
| HSP90 and hnRNPA2/B1 | HSP90 chaperone cycle for steroid hormone receptors (SHR) | 0.625 | 4.7274429919427 | 5.6527478293481 | 16 | 2 | 0.52737457499618 | 5.3179169946462 | 5.1275161362286 | 520005 |
| Tubulin beta-2 chain | HSP90 chaperone cycle for steroid hormone receptors (SHR) | 0.54166666666667 | 5.3697845939063 | 5.2542384943368 | 24 | 17 | 0.52737457499618 | 5.3179169946462 | 5.1275161362286 | 520005 |
| Peptidyl-prolyl cis-trans isomerase FKBP5 | HSP90 chaperone cycle for steroid hormone receptors (SHR) | 0.72131147540984 | 4.8986639239995 | 5.2997354054325 | 122 | 115 | 0.52737457499618 | 5.3179169946462 | 5.1275161362286 | 520005 |
| Tubulin beta-3 chain | HSP90 chaperone cycle for steroid hormone receptors (SHR) | 0.77777777777778 | 7.9022222222222 | 6.7425056150832 | 9 | 7 | 0.52737457499618 | 5.3179169946462 | 5.1275161362286 | 520005 |
| Tubulin beta-1 chain | HSP90 chaperone cycle for steroid hormone receptors (SHR) | 0.6038961038961 | 5.3294885216762 | 5.3840182759259 | 154 | 143 | 0.52737457499618 | 5.3179169946462 | 5.1275161362286 | 520005 |
| Sodium/myo-inositol cotransporter 2 | Inositol transporters | 0.66666666666667 | 5.4333333333333 | 5.0685261689129 | 3 | 3 | 0.66666666666667 | 5.4333333333333 | 5.0685261689129 | 3 |
| Kinesin-like protein KIF3C | Intraflagellar transport | 1 | 2 | 6.0237329237034 | 2 | 1 | 0.66248854915227 | 5.0826267238333 | 5.5998467555843 | 405296 |
| Tubulin | Intraflagellar transport | 0.72316032705297 | 5.1959502543901 | 5.7192183186131 | 33756 | 2146 | 0.66248854915227 | 5.0826267238333 | 5.5998467555843 | 405296 |
| Tubulin beta-2 chain | Intraflagellar transport | 0.54166666666667 | 5.3697845939063 | 5.2542384943368 | 24 | 17 | 0.66248854915227 | 5.0826267238333 | 5.5998467555843 | 405296 |
| Tubulin beta-3 chain | Intraflagellar transport | 0.77777777777778 | 7.9022222222222 | 6.7425056150832 | 9 | 7 | 0.66248854915227 | 5.0826267238333 | 5.5998467555843 | 405296 |
| Tubulin beta-1 chain | Intraflagellar transport | 0.6038961038961 | 5.3294885216762 | 5.3840182759259 | 154 | 143 | 0.66248854915227 | 5.0826267238333 | 5.5998467555843 | 405296 |
| IKK epsilon/TBK1 | IRF3 mediated activation of type 1 IFN | 0.91666666666667 | 4.7369126712735 | 5.4774045809888 | 24 | 12 | 0.58471668880035 | 4.5942649060293 | 4.8508401613298 | 4566 |
| Kinesin-like protein KIF3C | Kinesins | 1 | 2 | 6.0237329237034 | 2 | 1 | 0.53983409195438 | 4.2440234988988 | 5.159430820056 | 476690 |
| Tubulin | Kinesins | 0.72316032705297 | 5.1959502543901 | 5.7192183186131 | 33756 | 2146 | 0.53983409195438 | 4.2440234988988 | 5.159430820056 | 476690 |
| Kinesin-1 heavy chain | Kinesins | 0.76923076923077 | 5.263234588108 | 5.7906382081001 | 13 | 12 | 0.53983409195438 | 4.2440234988988 | 5.159430820056 | 476690 |
| Tubulin beta-2 chain | Kinesins | 0.54166666666667 | 5.3697845939063 | 5.2542384943368 | 24 | 17 | 0.53983409195438 | 4.2440234988988 | 5.159430820056 | 476690 |
| Tubulin beta-3 chain | Kinesins | 0.77777777777778 | 7.9022222222222 | 6.7425056150832 | 9 | 7 | 0.53983409195438 | 4.2440234988988 | 5.159430820056 | 476690 |
| Kinesin-like protein KIF2C | Kinesins | 0.58823529411765 | 5.0055429749974 | 5.4333640617631 | 17 | 15 | 0.53983409195438 | 4.2440234988988 | 5.159430820056 | 476690 |
| Kinesin-like protein KIFC1 | Kinesins | 0.6 | 5.2335 | 4.9933600135009 | 40 | 37 | 0.53983409195438 | 4.2440234988988 | 5.159430820056 | 476690 |
| Tubulin beta-1 chain | Kinesins | 0.6038961038961 | 5.3294885216762 | 5.3840182759259 | 154 | 143 | 0.53983409195438 | 4.2440234988988 | 5.159430820056 | 476690 |
| Kinesin-like protein KIF9 | Kinesins | 1 | 2 | 5.576930706625 | 1 | 1 | 0.53983409195438 | 4.2440234988988 | 5.159430820056 | 476690 |
| Elongation of very long chain fatty acids protein 1 | Linoleic acid (LA) metabolism | 0.5 | 5.0375 | 4.9531495180637 | 4 | 4 | 0.53355839848377 | 4.5471307579675 | 4.8798170534148 | 368 |
| Elongation of very long chain fatty acids protein 3 | Linoleic acid (LA) metabolism | 0.78571428571429 | 6.535 | 5.3084058210886 | 14 | 10 | 0.53355839848377 | 4.5471307579675 | 4.8798170534148 | 368 |
| Elongation of very long chain fatty acids protein 2 | Linoleic acid (LA) metabolism | 0.66666666666667 | 5 | 5.1998187132522 | 3 | 3 | 0.53355839848377 | 4.5471307579675 | 4.8798170534148 | 368 |
| Elongation of very long chain fatty acids protein 5 | Linoleic acid (LA) metabolism | 0.66666666666667 | 5 | 5.1998187132522 | 3 | 3 | 0.53355839848377 | 4.5471307579675 | 4.8798170534148 | 368 |
| Tubulin | Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane | 0.72316032705297 | 5.1959502543901 | 5.7192183186131 | 33756 | 2146 | 0.70868147806365 | 5.3732234646627 | 5.7323422850546 | 472771 |
| Tubulin beta-2 chain | Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane | 0.54166666666667 | 5.3697845939063 | 5.2542384943368 | 24 | 17 | 0.70868147806365 | 5.3732234646627 | 5.7323422850546 | 472771 |
| Tubulin beta-3 chain | Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane | 0.77777777777778 | 7.9022222222222 | 6.7425056150832 | 9 | 7 | 0.70868147806365 | 5.3732234646627 | 5.7323422850546 | 472771 |
| Tubulin beta-1 chain | Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane | 0.6038961038961 | 5.3294885216762 | 5.3840182759259 | 154 | 143 | 0.70868147806365 | 5.3732234646627 | 5.7323422850546 | 472771 |
| Kappa-casein | Miscellaneous transport and binding events | 1 | 5.9542425094393 | 5.6005167576607 | 1 | 1 | 1 | 5.9542425094393 | 5.6005167576607 | 1 |
| Acyl-coenzyme A thioesterase 2- mitochondrial | Mitochondrial Fatty Acid Beta-Oxidation | 0.75 | 4.25 | 5.4859952422297 | 4 | 4 | 0.75 | 4.25 | 5.4859952422297 | 8 |
| Acyl-coenzyme A thioesterase 1 | Mitochondrial Fatty Acid Beta-Oxidation | 0.75 | 4.25 | 5.4859952422297 | 4 | 4 | 0.75 | 4.25 | 5.4859952422297 | 8 |
| Kinetochore protein NDC80 homolog | Mitotic Prometaphase | 0.53846153846154 | 4.3076923076923 | 5.221002826705 | 13 | 5 | 0.51928730824178 | 5.4929650689925 | 5.1740521560171 | 505573 |
| Tubulin | Mitotic Prometaphase | 0.72316032705297 | 5.1959502543901 | 5.7192183186131 | 33756 | 2146 | 0.51928730824178 | 5.4929650689925 | 5.1740521560171 | 505573 |
| Tubulin beta-2 chain | Mitotic Prometaphase | 0.54166666666667 | 5.3697845939063 | 5.2542384943368 | 24 | 17 | 0.51928730824178 | 5.4929650689925 | 5.1740521560171 | 505573 |
| Tubulin beta-3 chain | Mitotic Prometaphase | 0.77777777777778 | 7.9022222222222 | 6.7425056150832 | 9 | 7 | 0.51928730824178 | 5.4929650689925 | 5.1740521560171 | 505573 |
| Aurora kinase B/Inner centromere protein | Mitotic Prometaphase | 0.54545454545454 | 8.0409090909091 | 5.1820640577436 | 22 | 10 | 0.51928730824178 | 5.4929650689925 | 5.1740521560171 | 505573 |
| Kinesin-like protein KIF2C | Mitotic Prometaphase | 0.58823529411765 | 5.0055429749974 | 5.4333640617631 | 17 | 15 | 0.51928730824178 | 5.4929650689925 | 5.1740521560171 | 505573 |
| Tubulin beta-1 chain | Mitotic Prometaphase | 0.6038961038961 | 5.3294885216762 | 5.3840182759259 | 154 | 143 | 0.51928730824178 | 5.4929650689925 | 5.1740521560171 | 505573 |
| Muscle glycogen synthase | Myoclonic epilepsy of Lafora | 0.66363636363636 | 6.3720048371326 | 5.298839983388 | 110 | 46 | 0.51931818181818 | 5.1599323401463 | 4.9730722560886 | 118 |
| Alpha-1-3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | N-glycan trimming and elongation in the cis-Golgi | 0.66666666666667 | 6.173104445408 | 5.212964223201 | 9 | 8 | 0.66666666666667 | 6.173104445408 | 5.212964223201 | 9 |
| 26S proteosome | NIK-->noncanonical NF-kB signaling | 0.67188240872451 | 5.7537684819849 | 5.902813128367 | 2109 | 58 | 0.54081763031596 | 5.5370929048977 | 5.3844097568501 | 90986 |
| Proteasome subunit beta type-9 | NIK-->noncanonical NF-kB signaling | 0.53658536585366 | 5.4363414634146 | 4.9952336804744 | 41 | 23 | 0.54081763031596 | 5.5370929048977 | 5.3844097568501 | 90986 |
| 26S proteosome | Orc1 removal from chromatin | 0.67188240872451 | 5.7537684819849 | 5.902813128367 | 2109 | 58 | 0.53495546970603 | 5.5327805760218 | 5.3794246948855 | 107671 |
| CDK1/Cyclin A | Orc1 removal from chromatin | 0.85714285714286 | 6.2061004678591 | 5.7827915249492 | 14 | 6 | 0.53495546970603 | 5.5327805760218 | 5.3794246948855 | 107671 |
| CDK2/Cyclin A1 | Orc1 removal from chromatin | 1 | 6.3750775913315 | 5.9652604435778 | 12 | 5 | 0.53495546970603 | 5.5327805760218 | 5.3794246948855 | 107671 |
| CDK2/CDK4 | Orc1 removal from chromatin | 1 | 5 | 7.2719444444444 | 12 | 6 | 0.53495546970603 | 5.5327805760218 | 5.3794246948855 | 107671 |
| Proteasome subunit beta type-9 | Orc1 removal from chromatin | 0.53658536585366 | 5.4363414634146 | 4.9952336804744 | 41 | 23 | 0.53495546970603 | 5.5327805760218 | 5.3794246948855 | 107671 |
| 26S proteosome | Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha | 0.67188240872451 | 5.7537684819849 | 5.902813128367 | 2109 | 58 | 0.51976954513589 | 5.5222271183091 | 5.209830105345 | 88129 |
| Proteasome subunit beta type-9 | Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha | 0.53658536585366 | 5.4363414634146 | 4.9952336804744 | 41 | 23 | 0.51976954513589 | 5.5222271183091 | 5.209830105345 | 88129 |
| Cyclin T1 | Pausing and recovery of HIV elongation | 0.8300283286119 | 10.750496508514 | 5.6731218252674 | 353 | 349 | 0.51931689535494 | 5.9633225594594 | 4.7490295318788 | 4063 |
| CDK9/Cyclin K | Pausing and recovery of HIV elongation | 0.875 | 6.2181023779453 | 5.6598086280743 | 8 | 3 | 0.51931689535494 | 5.9633225594594 | 4.7490295318788 | 4063 |
| CDK1/Cyclin A | Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes | 0.85714285714286 | 6.2061004678591 | 5.7827915249492 | 14 | 6 | 0.50591556374249 | 5.6666889477204 | 4.9017404551781 | 20364 |
| CDK2/Cyclin A1 | Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes | 1 | 6.3750775913315 | 5.9652604435778 | 12 | 5 | 0.50591556374249 | 5.6666889477204 | 4.9017404551781 | 20364 |
| Tubulin | Post-chaperonin tubulin folding pathway | 0.72316032705297 | 5.1959502543901 | 5.7192183186131 | 33756 | 2146 | 0.70777655000182 | 5.3843030403047 | 5.7331625329572 | 439015 |
| Tubulin beta-2 chain | Post-chaperonin tubulin folding pathway | 0.54166666666667 | 5.3697845939063 | 5.2542384943368 | 24 | 17 | 0.70777655000182 | 5.3843030403047 | 5.7331625329572 | 439015 |
| Tubulin beta-3 chain | Post-chaperonin tubulin folding pathway | 0.77777777777778 | 7.9022222222222 | 6.7425056150832 | 9 | 7 | 0.70777655000182 | 5.3843030403047 | 5.7331625329572 | 439015 |
| Tubulin beta-1 chain | Post-chaperonin tubulin folding pathway | 0.6038961038961 | 5.3294885216762 | 5.3840182759259 | 154 | 143 | 0.70777655000182 | 5.3843030403047 | 5.7331625329572 | 439015 |
| EZH2/SUZ12/EED/RBBP7/RBBP4 | PRC2 methylates histones and DNA | 0.8 | 7.66 | 5.6524222632749 | 55 | 7 | 0.52692430074463 | 5.7477940082908 | 4.691268849989 | 1939 |
| EZH1/SUZ12/EED/AEBP2/RBBP4 complex | PRC2 methylates histones and DNA | 0.75 | 5.305 | 4.8388892371782 | 20 | 4 | 0.52692430074463 | 5.7477940082908 | 4.691268849989 | 1939 |
| Histone-lysine N-methyltransferase EZH2 | PRC2 methylates histones and DNA | 0.61013986013986 | 6.7918978772026 | 5.1545634215876 | 572 | 334 | 0.52692430074463 | 5.7477940082908 | 4.691268849989 | 1939 |
| DNMT3A2/3L complex | PRC2 methylates histones and DNA | 0.71428571428571 | 4.4171428571429 | 4.9143338037472 | 21 | 7 | 0.52692430074463 | 5.7477940082908 | 4.691268849989 | 1939 |
| Tubulin | Prefoldin mediated transfer of substrate to CCT/TriC | 0.72316032705297 | 5.1959502543901 | 5.7192183186131 | 33756 | 2146 | 0.66520694306155 | 5.3837965424064 | 5.6546962428552 | 371513 |
| Tubulin beta-2 chain | Prefoldin mediated transfer of substrate to CCT/TriC | 0.54166666666667 | 5.3697845939063 | 5.2542384943368 | 24 | 17 | 0.66520694306155 | 5.3837965424064 | 5.6546962428552 | 371513 |
| Tubulin beta-3 chain | Prefoldin mediated transfer of substrate to CCT/TriC | 0.77777777777778 | 7.9022222222222 | 6.7425056150832 | 9 | 7 | 0.66520694306155 | 5.3837965424064 | 5.6546962428552 | 371513 |
| Tubulin beta-1 chain | Prefoldin mediated transfer of substrate to CCT/TriC | 0.6038961038961 | 5.3294885216762 | 5.3840182759259 | 154 | 143 | 0.66520694306155 | 5.3837965424064 | 5.6546962428552 | 371513 |
| Neurogenic locus notch homolog protein 2 | Pre-NOTCH Processing in Golgi | 1 | 9 | 5.1743475439684 | 1 | 1 | 0.55185655253837 | 7.3046467432854 | 4.7003199546323 | 660 |
| Neurogenic locus notch homolog protein 4 | Pre-NOTCH Processing in Golgi | 1 | 8.52 | 5.1743475439684 | 1 | 1 | 0.55185655253837 | 7.3046467432854 | 4.7003199546323 | 660 |
| Neurogenic locus notch homolog protein 3 | Pre-NOTCH Processing in Golgi | 0.55 | 8.0295 | 4.8169490448885 | 20 | 20 | 0.55185655253837 | 7.3046467432854 | 4.7003199546323 | 660 |
| Neurogenic locus notch homolog protein 2 | Pre-NOTCH Processing in the Endoplasmic Reticulum | 1 | 9 | 5.1743475439684 | 1 | 1 | 0.7575 | 8.1221462125472 | 4.975438917953 | 47 |
| Neurogenic locus notch homolog protein 4 | Pre-NOTCH Processing in the Endoplasmic Reticulum | 1 | 8.52 | 5.1743475439684 | 1 | 1 | 0.7575 | 8.1221462125472 | 4.975438917953 | 47 |
| Neurogenic locus notch homolog protein 3 | Pre-NOTCH Processing in the Endoplasmic Reticulum | 0.55 | 8.0295 | 4.8169490448885 | 20 | 20 | 0.7575 | 8.1221462125472 | 4.975438917953 | 47 |
| Beta-1-4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase | Reactions specific to the hybrid N-glycan synthesis pathway | 0.87096774193548 | 6.5891251208155 | 5.6369826414321 | 31 | 15 | 0.87096774193548 | 6.5891251208155 | 5.6369826414321 | 31 |
| Tubulin | Recruitment of NuMA to mitotic centrosomes | 0.72316032705297 | 5.1959502543901 | 5.7192183186131 | 33756 | 2146 | 0.52896258574145 | 5.0834698743195 | 5.0722404268186 | 558381 |
| CDK1/Cyclin A | Recruitment of NuMA to mitotic centrosomes | 0.85714285714286 | 6.2061004678591 | 5.7827915249492 | 14 | 6 | 0.52896258574145 | 5.0834698743195 | 5.0722404268186 | 558381 |
| CDK1/Cyclin E | Recruitment of NuMA to mitotic centrosomes | 0.66666666666667 | 5.5244149856255 | 5.9608462091247 | 6 | 3 | 0.52896258574145 | 5.0834698743195 | 5.0722404268186 | 558381 |
| Casein kinase I delta/epsilon | Recruitment of NuMA to mitotic centrosomes | 0.83333333333333 | 4.9397194536922 | 5.4699049781188 | 24 | 12 | 0.52896258574145 | 5.0834698743195 | 5.0722404268186 | 558381 |
| Tubulin beta-2 chain | Recruitment of NuMA to mitotic centrosomes | 0.54166666666667 | 5.3697845939063 | 5.2542384943368 | 24 | 17 | 0.52896258574145 | 5.0834698743195 | 5.0722404268186 | 558381 |
| Tubulin beta-3 chain | Recruitment of NuMA to mitotic centrosomes | 0.77777777777778 | 7.9022222222222 | 6.7425056150832 | 9 | 7 | 0.52896258574145 | 5.0834698743195 | 5.0722404268186 | 558381 |
| Tubulin beta-1 chain | Recruitment of NuMA to mitotic centrosomes | 0.6038961038961 | 5.3294885216762 | 5.3840182759259 | 154 | 143 | 0.52896258574145 | 5.0834698743195 | 5.0722404268186 | 558381 |
| Tubulin | Recycling pathway of L1 | 0.72316032705297 | 5.1959502543901 | 5.7192183186131 | 33756 | 2146 | 0.54010144071829 | 4.9114407210223 | 5.2147631128259 | 987148 |
| Tubulin beta-2 chain | Recycling pathway of L1 | 0.54166666666667 | 5.3697845939063 | 5.2542384943368 | 24 | 17 | 0.54010144071829 | 4.9114407210223 | 5.2147631128259 | 987148 |
| Tubulin beta-3 chain | Recycling pathway of L1 | 0.77777777777778 | 7.9022222222222 | 6.7425056150832 | 9 | 7 | 0.54010144071829 | 4.9114407210223 | 5.2147631128259 | 987148 |
| Tubulin beta-1 chain | Recycling pathway of L1 | 0.6038961038961 | 5.3294885216762 | 5.3840182759259 | 154 | 143 | 0.54010144071829 | 4.9114407210223 | 5.2147631128259 | 987148 |
| 26S proteosome | Regulation of activated PAK-2p34 by proteasome mediated degradation | 0.67188240872451 | 5.7537684819849 | 5.902813128367 | 2109 | 58 | 0.57504627592956 | 5.5800195579209 | 5.5430167384163 | 80658 |
| Proteasome subunit beta type-9 | Regulation of activated PAK-2p34 by proteasome mediated degradation | 0.53658536585366 | 5.4363414634146 | 4.9952336804744 | 41 | 23 | 0.57504627592956 | 5.5800195579209 | 5.5430167384163 | 80658 |
| IKK epsilon/TBK1 | Regulation of innate immune responses to cytosolic DNA | 0.91666666666667 | 4.7369126712735 | 5.4774045809888 | 24 | 12 | 0.58471668880035 | 4.5942649060293 | 4.8508401613298 | 2283 |
| 26S proteosome | Regulation of ornithine decarboxylase (ODC) | 0.67188240872451 | 5.7537684819849 | 5.902813128367 | 2109 | 58 | 0.56214577758344 | 5.5933648495781 | 5.481001802083 | 80352 |
| Proteasome subunit beta type-9 | Regulation of ornithine decarboxylase (ODC) | 0.53658536585366 | 5.4363414634146 | 4.9952336804744 | 41 | 23 | 0.56214577758344 | 5.5933648495781 | 5.481001802083 | 80352 |
| 26S proteosome | Regulation of RAS by GAPs | 0.67188240872451 | 5.7537684819849 | 5.902813128367 | 2109 | 58 | 0.55433931065009 | 5.5691872936401 | 5.4836991565992 | 79696 |
| Proteasome subunit beta type-9 | Regulation of RAS by GAPs | 0.53658536585366 | 5.4363414634146 | 4.9952336804744 | 41 | 23 | 0.55433931065009 | 5.5691872936401 | 5.4836991565992 | 79696 |
| 26S proteosome | Regulation of RUNX3 expression and activity | 0.67188240872451 | 5.7537684819849 | 5.902813128367 | 2109 | 58 | 0.53008706469001 | 5.5432473635129 | 5.3659637413481 | 104578 |
| Proteasome subunit beta type-9 | Regulation of RUNX3 expression and activity | 0.53658536585366 | 5.4363414634146 | 4.9952336804744 | 41 | 23 | 0.53008706469001 | 5.5432473635129 | 5.3659637413481 | 104578 |
| Proto-oncogene vav | Regulation of signaling by CBL | 1 | 8.98 | 6.1701802945981 | 1 | 1 | 0.49842707135258 | 6.0277629783303 | 4.8639243637111 | 99232 |
| PI3-kinase p85-alpha subunit | Regulation of signaling by CBL | 0.58333333333333 | 5.5716666666667 | 4.9949744849658 | 12 | 11 | 0.49842707135258 | 6.0277629783303 | 4.8639243637111 | 99232 |
| Tubulin | RHO GTPases activate IQGAPs | 0.72316032705297 | 5.1959502543901 | 5.7192183186131 | 33756 | 2146 | 0.50132058777774 | 5.2226415753745 | 5.1265637233279 | 665308 |
| POU domain- class 2- transcription factor 1 | RNA Polymerase III Abortive And Retractive Initiation | 0.66666666666667 | 3.58 | 4.7398100242315 | 3 | 1 | 0.51190476190476 | 3.4328571428571 | 4.5133715420983 | 17 |
| POU domain- class 2- transcription factor 1 | RNA Polymerase III Transcription Initiation From Type 3 Promoter | 0.66666666666667 | 3.58 | 4.7398100242315 | 3 | 1 | 0.66666666666667 | 3.58 | 4.7398100242315 | 6 |
| Apolipoprotein A-I | Scavenging by Class A Receptors | 1 | 5 | 5.9178191800746 | 1 | 1 | 0.51625 | 5.7568026633261 | 4.6253515895551 | 506 |
| Apolipoprotein A-I | Scavenging by Class B Receptors | 1 | 5 | 5.9178191800746 | 1 | 1 | 0.51368421052632 | 6.0401287426626 | 4.8772855866207 | 292 |
| 26S proteosome | SCF(Skp2)-mediated degradation of p27/p21 | 0.67188240872451 | 5.7537684819849 | 5.902813128367 | 2109 | 58 | 0.52094777115906 | 5.5788146721856 | 5.2407921656875 | 122869 |
| CDK4/Cyclin D3 | SCF(Skp2)-mediated degradation of p27/p21 | 0.6 | 4.450295589406 | 4.9641822833462 | 10 | 5 | 0.52094777115906 | 5.5788146721856 | 5.2407921656875 | 122869 |
| CDK2/CDK4 | SCF(Skp2)-mediated degradation of p27/p21 | 1 | 5 | 7.2719444444444 | 12 | 6 | 0.52094777115906 | 5.5788146721856 | 5.2407921656875 | 122869 |
| CDK1/Cyclin A | SCF(Skp2)-mediated degradation of p27/p21 | 0.85714285714286 | 6.2061004678591 | 5.7827915249492 | 14 | 6 | 0.52094777115906 | 5.5788146721856 | 5.2407921656875 | 122869 |
| G1/S-specific cyclin D1 | SCF(Skp2)-mediated degradation of p27/p21 | 0.72727272727273 | 4.1818181818182 | 5.3295213285972 | 11 | 9 | 0.52094777115906 | 5.5788146721856 | 5.2407921656875 | 122869 |
| CDK1/Cyclin E | SCF(Skp2)-mediated degradation of p27/p21 | 0.66666666666667 | 5.5244149856255 | 5.9608462091247 | 6 | 3 | 0.52094777115906 | 5.5788146721856 | 5.2407921656875 | 122869 |
| CDK3/Cyclin E | SCF(Skp2)-mediated degradation of p27/p21 | 0.66666666666667 | 5.6507399404421 | 5.7467683563357 | 12 | 6 | 0.52094777115906 | 5.5788146721856 | 5.2407921656875 | 122869 |
| CDK2/Cyclin A1 | SCF(Skp2)-mediated degradation of p27/p21 | 1 | 6.3750775913315 | 5.9652604435778 | 12 | 5 | 0.52094777115906 | 5.5788146721856 | 5.2407921656875 | 122869 |
| Proteasome subunit beta type-9 | SCF(Skp2)-mediated degradation of p27/p21 | 0.53658536585366 | 5.4363414634146 | 4.9952336804744 | 41 | 23 | 0.52094777115906 | 5.5788146721856 | 5.2407921656875 | 122869 |
| 26S proteosome | SCF-beta-TrCP mediated degradation of Emi1 | 0.67188240872451 | 5.7537684819849 | 5.902813128367 | 2109 | 58 | 0.58219255042243 | 5.6102511489448 | 5.5705767988487 | 79596 |
| Proteasome subunit beta type-9 | SCF-beta-TrCP mediated degradation of Emi1 | 0.53658536585366 | 5.4363414634146 | 4.9952336804744 | 41 | 23 | 0.58219255042243 | 5.6102511489448 | 5.5705767988487 | 79596 |
| 26S proteosome | Separation of Sister Chromatids | 0.67188240872451 | 5.7537684819849 | 5.902813128367 | 2109 | 58 | 0.55671194599482 | 5.5627428633945 | 5.4099592220055 | 585169 |
| Kinetochore protein NDC80 homolog | Separation of Sister Chromatids | 0.53846153846154 | 4.3076923076923 | 5.221002826705 | 13 | 5 | 0.55671194599482 | 5.5627428633945 | 5.4099592220055 | 585169 |
| Tubulin | Separation of Sister Chromatids | 0.72316032705297 | 5.1959502543901 | 5.7192183186131 | 33756 | 2146 | 0.55671194599482 | 5.5627428633945 | 5.4099592220055 | 585169 |
| Proteasome subunit beta type-9 | Separation of Sister Chromatids | 0.53658536585366 | 5.4363414634146 | 4.9952336804744 | 41 | 23 | 0.55671194599482 | 5.5627428633945 | 5.4099592220055 | 585169 |
| Tubulin beta-2 chain | Separation of Sister Chromatids | 0.54166666666667 | 5.3697845939063 | 5.2542384943368 | 24 | 17 | 0.55671194599482 | 5.5627428633945 | 5.4099592220055 | 585169 |
| Tubulin beta-3 chain | Separation of Sister Chromatids | 0.77777777777778 | 7.9022222222222 | 6.7425056150832 | 9 | 7 | 0.55671194599482 | 5.5627428633945 | 5.4099592220055 | 585169 |
| Aurora kinase B/Inner centromere protein | Separation of Sister Chromatids | 0.54545454545454 | 8.0409090909091 | 5.1820640577436 | 22 | 10 | 0.55671194599482 | 5.5627428633945 | 5.4099592220055 | 585169 |
| Kinesin-like protein KIF2C | Separation of Sister Chromatids | 0.58823529411765 | 5.0055429749974 | 5.4333640617631 | 17 | 15 | 0.55671194599482 | 5.5627428633945 | 5.4099592220055 | 585169 |
| Tubulin beta-1 chain | Separation of Sister Chromatids | 0.6038961038961 | 5.3294885216762 | 5.3840182759259 | 154 | 143 | 0.55671194599482 | 5.5627428633945 | 5.4099592220055 | 585169 |
| D-3-phosphoglycerate dehydrogenase | Serine biosynthesis | 1 | 5 | 7.0892890590442 | 1 | 1 | 1 | 5 | 7.0892890590442 | 1 |
| Mitogen-activated protein kinase 7 | Signalling to ERK5 | 0.54736842105263 | 5.3281037474288 | 5.0894734159103 | 190 | 128 | 0.51544991511036 | 5.4411983125915 | 4.9876005860339 | 504 |
| Choline kinase alpha | Synthesis of PE | 0.68807339449541 | 5.0837473168955 | 5.2661521590979 | 109 | 104 | 0.61080109713421 | 4.7033199672574 | 5.0418314703065 | 207 |
| Choline/ethanolamine kinase | Synthesis of PE | 1 | 4.66 | 5.8856897980017 | 1 | 1 | 0.61080109713421 | 4.7033199672574 | 5.0418314703065 | 207 |
| Phospholipase D2 | Synthesis of PG | 0.5570652173913 | 6.1190583596343 | 5.0551648754195 | 368 | 261 | 0.54515712901904 | 6.0018226976227 | 4.5603210611356 | 759 |
| Phospholipase D1 | Synthesis of PG | 0.57840616966581 | 6.5564097332337 | 5.1172227723543 | 389 | 277 | 0.54515712901904 | 6.0018226976227 | 4.5603210611356 | 759 |
| Membrane-associated phosphatidylinositol transfer protein 1 | Synthesis of PI | 1 | 5.725371921463 | 6.1292813556889 | 2 | 2 | 1 | 5.725371921463 | 6.1292813556889 | 2 |
| 26S proteosome | The role of GTSE1 in G2/M progression after G2 checkpoint | 0.67188240872451 | 5.7537684819849 | 5.902813128367 | 2109 | 58 | 0.54409978814084 | 5.4518235813618 | 5.3602310833789 | 656895 |
| Tubulin | The role of GTSE1 in G2/M progression after G2 checkpoint | 0.72316032705297 | 5.1959502543901 | 5.7192183186131 | 33756 | 2146 | 0.54409978814084 | 5.4518235813618 | 5.3602310833789 | 656895 |
| CDK1/Cyclin A | The role of GTSE1 in G2/M progression after G2 checkpoint | 0.85714285714286 | 6.2061004678591 | 5.7827915249492 | 14 | 6 | 0.54409978814084 | 5.4518235813618 | 5.3602310833789 | 656895 |
| CDK1/Cyclin E | The role of GTSE1 in G2/M progression after G2 checkpoint | 0.66666666666667 | 5.5244149856255 | 5.9608462091247 | 6 | 3 | 0.54409978814084 | 5.4518235813618 | 5.3602310833789 | 656895 |
| HSP90 and hnRNPA2/B1 | The role of GTSE1 in G2/M progression after G2 checkpoint | 0.625 | 4.7274429919427 | 5.6527478293481 | 16 | 2 | 0.54409978814084 | 5.4518235813618 | 5.3602310833789 | 656895 |
| Proteasome subunit beta type-9 | The role of GTSE1 in G2/M progression after G2 checkpoint | 0.53658536585366 | 5.4363414634146 | 4.9952336804744 | 41 | 23 | 0.54409978814084 | 5.4518235813618 | 5.3602310833789 | 656895 |
| Tubulin beta-2 chain | The role of GTSE1 in G2/M progression after G2 checkpoint | 0.54166666666667 | 5.3697845939063 | 5.2542384943368 | 24 | 17 | 0.54409978814084 | 5.4518235813618 | 5.3602310833789 | 656895 |
| Tubulin beta-3 chain | The role of GTSE1 in G2/M progression after G2 checkpoint | 0.77777777777778 | 7.9022222222222 | 6.7425056150832 | 9 | 7 | 0.54409978814084 | 5.4518235813618 | 5.3602310833789 | 656895 |
| Tubulin beta-1 chain | The role of GTSE1 in G2/M progression after G2 checkpoint | 0.6038961038961 | 5.3294885216762 | 5.3840182759259 | 154 | 143 | 0.54409978814084 | 5.4518235813618 | 5.3602310833789 | 656895 |
| 26S proteosome | TNFR2 non-canonical NF-kB pathway | 0.67188240872451 | 5.7537684819849 | 5.902813128367 | 2109 | 58 | 0.52481870973723 | 5.4623021867095 | 5.2601175283766 | 82721 |
| Proteasome subunit beta type-9 | TNFR2 non-canonical NF-kB pathway | 0.53658536585366 | 5.4363414634146 | 4.9952336804744 | 41 | 23 | 0.52481870973723 | 5.4623021867095 | 5.2601175283766 | 82721 |
| Acetyl-coenzyme A transporter 1 | Transport of vitamins, nucleosides, and related molecules | 0.68874172185431 | 8.7094701986755 | 5.2463583945705 | 151 | 144 | 0.68874172185431 | 8.7094701986755 | 5.2463583945705 | 151 |
| Diacylglycerol O-acyltransferase 1 | Triglyceride biosynthesis | 0.61222780569514 | 6.5864022611869 | 5.1502880369796 | 1194 | 783 | 0.61042159489391 | 5.475699041569 | 4.9949017990275 | 1445 |
| Glycerol kinase | Triglyceride biosynthesis | 1 | 4.1 | 5.2262721390948 | 1 | 1 | 0.61042159489391 | 5.475699041569 | 4.9949017990275 | 1445 |
| Diacylglycerol O-acyltransferase 2 | Triglyceride biosynthesis | 0.51724137931034 | 4.2472968188246 | 4.9329667278673 | 29 | 25 | 0.61042159489391 | 5.475699041569 | 4.9949017990275 | 1445 |
| 26S proteosome | Ubiquitin Mediated Degradation of Phosphorylated Cdc25A | 0.67188240872451 | 5.7537684819849 | 5.902813128367 | 2109 | 58 | 0.54865015131574 | 5.5446705431102 | 5.4304154818732 | 96213 |
| Proteasome subunit beta type-9 | Ubiquitin Mediated Degradation of Phosphorylated Cdc25A | 0.53658536585366 | 5.4363414634146 | 4.9952336804744 | 41 | 23 | 0.54865015131574 | 5.5446705431102 | 5.4304154818732 | 96213 |
| 26S proteosome | Ubiquitin-dependent degradation of Cyclin D1 | 0.67188240872451 | 5.7537684819849 | 5.902813128367 | 2109 | 58 | 0.54826353428171 | 5.5467713928774 | 5.335998253058 | 96066 |
| CDK4/Cyclin D3 | Ubiquitin-dependent degradation of Cyclin D1 | 0.6 | 4.450295589406 | 4.9641822833462 | 10 | 5 | 0.54826353428171 | 5.5467713928774 | 5.335998253058 | 96066 |
| CDK2/CDK4 | Ubiquitin-dependent degradation of Cyclin D1 | 1 | 5 | 7.2719444444444 | 12 | 6 | 0.54826353428171 | 5.5467713928774 | 5.335998253058 | 96066 |
| G1/S-specific cyclin D1 | Ubiquitin-dependent degradation of Cyclin D1 | 0.72727272727273 | 4.1818181818182 | 5.3295213285972 | 11 | 9 | 0.54826353428171 | 5.5467713928774 | 5.335998253058 | 96066 |
| Proteasome subunit beta type-9 | Ubiquitin-dependent degradation of Cyclin D1 | 0.53658536585366 | 5.4363414634146 | 4.9952336804744 | 41 | 23 | 0.54826353428171 | 5.5467713928774 | 5.335998253058 | 96066 |
| 26S proteosome | Vif-mediated degradation of APOBEC3G | 0.67188240872451 | 5.7537684819849 | 5.902813128367 | 2109 | 58 | 0.578837752446 | 5.5585247157047 | 5.5263054783935 | 79620 |
| Proteasome subunit beta type-9 | Vif-mediated degradation of APOBEC3G | 0.53658536585366 | 5.4363414634146 | 4.9952336804744 | 41 | 23 | 0.578837752446 | 5.5585247157047 | 5.5263054783935 | 79620 |
| 26S proteosome | Vpu mediated degradation of CD4 | 0.67188240872451 | 5.7537684819849 | 5.902813128367 | 2109 | 58 | 0.57091387909135 | 5.5891659529278 | 5.5294476767644 | 79645 |
| Proteasome subunit beta type-9 | Vpu mediated degradation of CD4 | 0.53658536585366 | 5.4363414634146 | 4.9952336804744 | 41 | 23 | 0.57091387909135 | 5.5891659529278 | 5.5294476767644 | 79645 |
| Tyrosine-protein kinase transmembrane receptor ROR2 | WNT5A-dependent internalization of FZD2, FZD5 and ROR2 | 1 | 5 | 5.04015625 | 1 | 1 | 0.64516129032258 | 4.1764648186121 | 4.7512467570713 | 32 |
