This is a sampling view of the sort of assays selected to configure a cytotox score.
The activity distribution histogram of the chemblScores recorded for the above assays, more than 2.6M records corresponding to 73k compounds.
And this is the activity distribution histogram of the chemblScores of these 73k molecules on non-toxicity assays…
…and the assay types that the 73k molecules have faced to…
Looking at correlation between cytotoxScores and overall chemblScores, we can identify a number of protein targets associated with cytotoxicity. Here is a sample with slopes >0.3 and R squared >0.5.
