drTarget portfolio target-disease associations for hematological disorders DrTarget’s AI-Powered Indication Expansion for Hematological Disorders

AI-Driven Target Discovery for Hematological Disorders

DrTarget’s AI-powered portfolio integrates machine learning, genomics, and bioinformatics to identify novel targets and therapeutic opportunities for hematological diseases. By analyzing data from Open Targets, PubChem, and other public repositories, our models accelerate drug discovery and repurposing in the following areas:

✔ Leukemias & Lymphomas
✔ Anemia & Hemoglobinopathies (e.g., Sickle Cell Disease, Thalassemia)
✔ Coagulation & Platelet Disorders (e.g., Hemophilia, Thrombocytopenia)
✔ Myelodysplastic Syndromes (MDS) & Bone Marrow Failure Syndromes
✔ Rare Blood Disorders & Immune-Mediated Conditions

Target-disease associations for hematological diseases.

Check best scored target-disease associations in table:

BioAssay Name	diseaseName	program	assayType	associationScore	numberOfEvidences	testedCompounds	activeCompounds
Factor XIa 1536 HTS	deep vein thrombosis	F11_modulation	targetBased	0.55243395918738	42	218707	302
Thrombin 1536 HTS	deep vein thrombosis	F2_modulation	targetBased	0.640640436953824	362	217233	557
High Content Assay for Compounds that inhibit the Assembly of the Perinucleolar Compartment	erythrocyte count	PTBP1	targetBased	0.343598716536876	8	139718	4338
qHTS Assay for Activators of Human Muscle isoform 2 Pyruvate Kinase	erythrocyte count	PKM	targetBased	0.175735520140899	8	263662	892
Primary Cell-based High Throughput Screening assay for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA)	erythrocyte count	RORA	pathwayBased	0.310829787620133	5	64908	979
Primary Cell-based High Throughput Screening assay for inhibitors of the Retinoic Acid Receptor-related orphan receptor A (RORA)	erythrocyte count	RORA	pathwayBased	0.310829787620133	5	64908	278
HTS to identify compounds that promote myeloid differentiation with MLPCN compound set	erythrocyte count	HOXA9	pathwayBased	0.427400188188329	9	358556	3721
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	erythrocyte count	JAK2	targetBased	0.397074669638367	18	217959	2390
Identification of CBX7 inhibitors - Primary Alpha Screen	erythrocyte count	Chromobox protein homolog 7 inhibitors	targetBased	0.395732295016599	6	64999	724
qHTS for Inhibitors of Polymerase Iota	erythrocyte count	POLI	targetBased	0.3006210831632	12	386063	3989
High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Primary Screen	erythrocyte count	NFKB1	pathwayBased	0.445691141250529	5	193265	3100
uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay	erythrocyte count	NFKB1	pathwayBased	0.445691141250529	5	359244	3094
uHTS identification of HIF-2a Inhibitors in a luminesence assay	erythrocyte count	HIF-2a_inhibitors	targetBased	0.451337824039821	53	363840	2624
uHTS identification of Caspase-8 TRAIL sensitizers in a luminesence assay	erythrocyte count	TNFRSF10B	targetBased	0.382995094067906	5	363840	3764
Fluorescence-based biochemical high throughput primary assay to identify inhibitors of phospholipase C isozymes (PLC-gamma1).	erythrocyte count	PLCG1	targetBased	0.413111023310293	5	369953	3123
HTS for PAX8 inhibitors using PAX8 luciferase reporter gene assay in RMG-I cells Measured in Cell-Based System Using Plate Reader - 7054-01_Inhibitor_SinglePoint_HTS_Activity	erythrocyte count	PAX8	targetBased	0.423257012742155	9	353950	4145
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	erythrocyte count	PPARG	targetBased	0.494157315172562	14	99314	335
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	erythrocyte count	PPARG	targetBased	0.494157315172562	14	196176	782
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	erythrocyte count	PPARG	targetBased	0.494157315172562	14	99314	390
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	erythrocyte count	PPARG	targetBased	0.494157315172562	14	196177	811
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	erythrocyte count	PPARG	targetBased	0.494157315172562	14	196176	670
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	erythrocyte count	PPARG	targetBased	0.494157315172562	14	196177	519
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of 5-meCpG-binding domain protein 2 (MBD2)-DBD binding to methylated oligonucleotide	erythrocyte count	MBD2	targetBased	0.224016995925638	11	369953	1149
E3 Ligase HTS_1536	erythrocyte count	MDM2	targetBased	0.450464970018618	8	207811	220
uHTS Luminescent assay for identification of inhibitors of Sentrin-specific protease 7 (SENP7)	erythrocyte count	SENP7	targetBased	0.408357866663354	8	331670	4902
Factor XIa 1536 HTS	partial thromboplastin time	F11_modulation	targetBased	0.499930029403081	8	218707	302
Factor XIIa 1536 HTS	partial thromboplastin time	F12_modulation	targetBased	0.248378617807934	5	217430	649
HTS for Estrogen Receptor-beta Coactivator Binding inhibitors	erythrocyte count	ESR2_inhibitors	targetBased	0.538077017074459	11	86095	1114
qHTS assay for re-activators of p53 using a Luc reporter	erythrocyte count	TP53	pathwayBased	0.238462270482408	8	321427	201
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Nonpermissive Temperature	erythrocyte count	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.238462270482408	8	54509	528
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Permissive Temperature	erythrocyte count	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.238462270482408	8	54513	338
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature	erythrocyte count	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.238462270482408	8	125394	1890
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Permissive Temperature	erythrocyte count	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.238462270482408	8	124022	1156
qHTS assay to identify small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway	erythrocyte count	RORCgammaPathwayInhibitors	pathwayBased	0.164356631709751	5	7671	874
VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity	erythrocyte count	RORC	targetBased	0.164356631709751	5	304060	10600
qHTS for inhibitors of ROR gamma transcriptional activity	erythrocyte count	RORCgammaPathwayInhibitors	pathwayBased	0.164356631709751	5	305439	16717
Inhibitors of CDC25B-CDK2/CyclinA interaction	erythrocyte count	Inhibitors of CDC25B-CDK2/CyclinA interaction	targetBased	0.360385907222518	9	93798	679
Fluorescence-based biochemical high throughput primary assay to identify inhibitors of phospholipase C isozymes (PLC-beta3).	erythrocyte count	PLCB3	targetBased	0.231403775724767	8	369953	662
Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2	erythrocyte count	THRB	targetBased	0.512458045532973	12	276265	806
Luminescence Cell-Based Primary HTS to Identify Inhibitors of A1 Apoptosis.	erythrocyte count	BCL2L11_inhibitors	targetBased	0.496921788988629	39	325630	216
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb via a fluorescence resonance energy transfer (FRET) assay.	erythrocyte count	RUNX1	targetBased	0.306956394720916	17	215667	993
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay.	erythrocyte count	RUNX1	targetBased	0.306956394720916	17	218234	1620
Inhibitors of USP1/UAF1: Primary Screen	erythrocyte count	USP1	targetBased	0.257058556464418	6	389569	904
HTS Luminescent assay for identification of inhibitors of Sentrin-specific protease 8 (SENP8)	erythrocyte count	SENP8	targetBased	0.157120560118742	8	330392	4119
uHTS Fluorescent Assay Using Nedd8 Protein Substrate for Identification of Inhibitors of Sentrin-Specific Protease 8 (SENP8)	erythrocyte count	SENP8	targetBased	0.157120560118742	8	363840	2341
HTS of Smad transcription factor inhibitors	erythrocyte count	SMAD3	targetBased	0.258590882274137	8	88033	251
Primary cell-based screen for identification of compounds that inhibit the two-pore domain potassium channel KCNK3	erythrocyte count	KCNK3	targetBased	0.288998038461588	5	339674	2841
Primary biochemical high throughput screening assay to identify inhibitors of BCL2-related protein, long isoform (BCLXL).	erythrocyte count	BCL2L1_modulators	targetBased	0.205572718989908	8	314998	2199
Inhibition of the MLL-AF4-AF9 Interaction in Pediatric Leukemia Measured in Biochemical System Using Plate Reader - 2160-01_Inhibitor_SinglePoint_HTS_Activity	erythrocyte count	MLLT3	targetBased	0.299121080786815	6	344459	1627
Primary qHTS assay for small molecule inhibitors of Inositol hexaphosphate kinase 1 (IP6K1)	erythrocyte count	IP6K1	targetBased	0.103772190490666	8	143229	1157
qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding	erythrocyte count	MAPT	pathwayBased	0.287118305584391	15	267412	5703
qHTS Assay for Tau Filament Binding	erythrocyte count	MAPT	targetBased	0.287118305584391	15	69668	1391
qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization	erythrocyte count	MAPT	pathwayBased	0.287118305584391	15	271402	1048
AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of microphthalmia-associated transcription factor (MITF)	erythrocyte count	MITF inhibitors	targetBased	0.478974649059876	8	642362	5830
MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Inhibitor_SinglePoint_HTS_Activity	erythrocyte count	MITF	targetBased	0.478974649059876	8	331360	2760
Primary qHTS for Inhibitors of ATXN expression	erythrocyte count	ATXN2_repressors	targetBased	0.280846505262666	9	358434	2554
Identification of Small Molecule Correctors of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Delta508 Mutation Function in Human Bronchial Epithelial Cells. Measured in Cell-Based System Using Plate Reader - 7017-01_Other_SinglePoint_HTS_Activity	leukocyte count	cftrCorrectors	targetBased	0.301749485769024	5	343786	1253
Fluorescence Polarization with CAL-PDZ Measured in Biochemical System Using Plate Reader - 2109-02_Inhibitor_SinglePoint_HTS_Activity	leukocyte count	cftrTrafficModulators	targetBased	0.301749485769024	5	296501	2737
HTS for developing T Cell Immune Modulators	leukocyte count	ITGAL	targetBased	0.431322457929625	32	326271	221
Identification of agents that induce E-selectin on human endothelial cells Measured in Cell-Based System Using Imaging - 2152-01_Activator_SinglePoint_HTS_Activity	leukocyte count	SELE	targetBased	0.192305649473507	11	257988	963
Primary HTS assay for chemical inhibitors of TNF alpha stimulated E-Selectin expression	leukocyte count	E-selectinExpression	targetBased	0.192305649473507	11	118096	843
qHTS Assay to Identify Small Molecule Activators of BRCA1 Expression	leukocyte count	BRCA1 activation	pathwayBased	0.148597790038532	8	376029	3978
HTS to identify compounds that promote myeloid differentiation with MLPCN compound set	leukocyte count	HOXA9	pathwayBased	0.358966277440597	15	358556	3721
qHTS assay for MDR1-selective chemotherapeutics: Primary screen using the drug-selected MDR subline cells KB-V1	leukocyte count	MDR1-selectiveÃ‚Â compounds	targetBased	0.151947139053729	6	396029	13426
qHTS assay for MDR1-selective chemotherapeutics: Primary screen using the parental adenocarcinoma cell KB-3-1	leukocyte count	MDR1-selectiveÃ‚Â compounds	targetBased	0.151947139053729	6	395981	5516
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	leukocyte count	JAK2	targetBased	0.478792584343245	26	217959	2390
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of the interaction of the Ras and Rab interactor 1 protein (Rin1) and the c-abl oncogene 1, non-receptor tyrosine kinase (Abl)	leukocyte count	ABL1_interaction	targetBased	0.37012683316935	8	359207	1432
Identification of CBX7 inhibitors - Primary Alpha Screen	leukocyte count	Chromobox protein homolog 7 inhibitors	targetBased	0.44907886381902	19	64999	724
qHTS for Inhibitors of Polymerase Iota	leukocyte count	POLI	targetBased	0.199549567439058	19	386063	3989
qHTS Assay for Inhibitors of the CtBP/E1A Interaction	leukocyte count	RBBP8	targetBased	0.337520242036241	11	335214	1652
uHTS HTRF assay for identification of inhibitors of SUMOylation	leukocyte count	UBE2I	targetBased	0.265680957617967	13	290915	1039
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype	leukocyte count	RAB2A	targetBased	0.42448342804523	13	194628	365
Luminescence Cell-Free Homogenous Primary HTS to Identify Inhibitors of GSK-3 alpha	leukocyte count	GSK3A	targetBased	0.108464099012194	17	315412	318
HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails	leukocyte count	HP1-betaChromodomainInteractionsInhibitors	targetBased	0.112791028973846	7	383363	2142
High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Primary Screen	leukocyte count	NFKB1	pathwayBased	0.410789179556338	34	193265	3100
uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay	leukocyte count	NFKB1	pathwayBased	0.410789179556338	34	359244	3094
Toxoplasma gondii inhibition HTS in the presence of IFN-y	leukocyte count	IFNG	targetBased	0.399050681085795	7	67275	2509
Flow Cytometric HTS Screen for inhibitors of the ABC transporter ABCB6 for MLPCN Compound Set	leukocyte count	ABCB6_inhibitors	targetBased	0.108537345169556	11	362098	692
Antagonist identification of Pyk2 oligomerization: high-throughput screening cellular assay	leukocyte count	Pyk2Ã‚Â	targetBased	0.340061354976903	14	98749	818
qHTS Assay for Inhibitors of BAZ2B	leukocyte count	BAZ2B_modulators	targetBased	0.272713761413137	15	356826	15709
uHTS identification of DNMT1 inhibitors in a Fluorescent Molecular Beacon assay	leukocyte count	DNMT1	targetBased	0.219151923345434	18	359244	2975
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	leukocyte count	PPARG	targetBased	0.428857518932601	36	99314	335
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	leukocyte count	PPARG	targetBased	0.428857518932601	36	196176	782
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	leukocyte count	PPARG	targetBased	0.428857518932601	36	99314	390
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	leukocyte count	PPARG	targetBased	0.428857518932601	36	196177	811
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	leukocyte count	PPARG	targetBased	0.428857518932601	36	196176	670
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	leukocyte count	PPARG	targetBased	0.428857518932601	36	196177	519
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of 5-meCpG-binding domain protein 2 (MBD2)-DBD binding to methylated oligonucleotide	leukocyte count	MBD2	targetBased	0.395337912514739	15	369953	1149
qHTS for Activators of Integrin-Mediated Alleviation for Muscular Dystrophy	leukocyte count	CGA_integrin_activators	targetBased	0.157111787971819	21	345855	222
E3 Ligase HTS_1536	leukocyte count	MDM2	targetBased	0.405158182124266	4	207811	220
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac activated mutant	leukocyte count	RAC1	targetBased	0.113157747762871	5	194629	219
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac wildtype	leukocyte count	RAC1	targetBased	0.113157747762871	5	194628	521
High throughput screening of activators of transient receptor potential cation channel C6 (TRPC6)	leukocyte count	TRPC6	targetBased	0.384047761380901	7	305610	382
High throughput screening of inhibitors of transient receptor potential cation channel C6 (TRPC6)	leukocyte count	TRPC6	targetBased	0.384047761380901	7	305610	3253
Luminescence cell-based high throughput primary assay to identify inhibitors of TEAD-YAP interaction.	leukocyte count	YAP1	targetBased	0.428380266340331	6	639428	9218
QFRET-based biochemical primary high throughput screening assay to identify exosite inhibitors of ADAM10.	leukocyte count	ADAM10_inhibitors	targetBased	0.122395207949565	10	369953	2294
USP8 deubiquitinase inhibition: Primary qHTS	leukocyte count	USP8	targetBased	0.206840373894517	9	47480	2010
Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bfl-1	leukocyte count	BCL2A1_modulators	targetBased	0.482721693659834	38	194826	237
qHTS Assay for NPC1 Promoter Activators	leukocyte count	NPC1	pathwayBased	0.457261117573377	23	320682	7575
HTS Assay for Inhibitors of Akt Phophorylation: Primary Screen	leukocyte count	AKT1_inhibitors	targetBased	0.289177527830088	8	356517	1139
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of myeloid cell leukemia sequence 1 (MCL1) interactions with BIM-BH3 peptide.	leukocyte count	MCL1	targetBased	0.214937188662602	31	314998	2139
uHTS of Mcl-1/Bid interaction inhibitors	leukocyte count	MCL1	targetBased	0.214937188662602	31	218602	2129
uHTS of Mcl-1/Noxa interaction inhibitors	leukocyte count	MCL1	targetBased	0.214937188662602	31	217330	3334
qHTS Assay for Identifying a Potential Treatment of Ataxia-Telangiectasia	leukocyte count	ATM_modulators	targetBased	0.365505027044539	29	322361	619
Luminescence Cell-Based Primary HTS to Identify Inhibitors of A1 Apoptosis.	leukocyte count	BCL2L11_inhibitors	targetBased	0.435723565337047	69	325630	216
uHTS Fluorescent assay for identification of inhibitors of hexokinase domain containing I (HKDC1)	leukocyte count	HKDC1	targetBased	0.362703282541246	10	340696	540
Dyrk1 A HTS Measured in Biochemical System Using Plate Reader - 2124-01_Inhibitor_SinglePoint_HTS_Activity	leukocyte count	DYRK1A_inhibitors	targetBased	0.414617961099815	19	310014	1321
HTS identification of compounds inhibiting the binding of CD11b/CD18 to fibrinogen via a luminescence assay.	leukocyte count	ITGB2	targetBased	0.339383094548391	6	92518	501
qHTS Assay for Inhibitors of 15-hLO (15-human lipoxygenase)	leukocyte count	ALOX15_inhibitors	targetBased	0.266671163078938	30	73174	1034
Primary HTS assay for chemical inhibitors of TNF alpha stimulated VCAM1 expression	leukocyte count	VCAM1_expression	targetBased	0.486973027927605	33	94498	457
uHTS Luminescent assay for identification of inhibitors of NALP3 in yeast	leukocyte count	NLRP3	targetBased	0.494054010925652	34	330392	1295
Fluorescence-based primary biochemical high throughput screening assay to identify inhibitors of human diacylglycerol lipase, beta (DAGLB)	leukocyte count	DAGLB_inhibitors	targetBased	0.212713601362903	27	343468	202
CYP2C19 Assay	leukocyte count	CYP2C19_inhibitors	targetBased	0.14816743618703	4	95857	20295
Luminescence-based cell-based primary high throughput screening assay to identify biased ligands of the melanocortin 4 receptor (MC4R): agonists of MC4R	leukocyte count	MC4R	targetBased	0.332963602419637	6	356160	3470
TRFRET-based cell-based primary high throughput screening assay to identify biased ligands of the melanocortin 4 receptor (MC4R): antagonists of MC4R	leukocyte count	MC4R	targetBased	0.332963602419637	6	356160	1703
HTS for Beta-2AR agonists via FAP method	leukocyte count	ADRB2_activators	targetBased	0.506555108845403	36	339297	1446
Primary HTS and Confirmation Assays for S1P1 Agonists and Agonism Potentiators	leukocyte count	S1PR1	targetBased	0.211294058872413	42	55710	315
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	leukocyte count	FGB_inhibitors	targetBased	0.429115998747175	6	369953	760
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	leukocyte count	FGB_inhibitors	targetBased	0.429115998747175	6	369953	498
qHTS for Inhibitors of TGF-b	anemia (phenotype)	TGFB1	pathwayBased	0.524892488999053	11	403345	4970
Inhibitors of the vitamin D receptor (VDR): qHTS	anemia (phenotype)	VDR	targetBased	0.583287797794901	8	394050	3624
Absorbance-based biochemical primary high throughput screening assay to identify activators of Methionine sulfoxide reductase A (MsrA)	leukocyte count	MSRA	targetBased	0.147003770565825	9	362026	1074
Absorbance-based biochemical primary high throughput screening assay to identify inhibitors of Methionine sulfoxide reductase A (MsrA)	leukocyte count	MSRA	targetBased	0.147003770565825	9	362577	2709
qHTS Assay for the Inhibitors of L3MBTL1	leukocyte count	L3MBTL1	targetBased	0.127222050174717	4	225309	1492
qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding	leukocyte count	MAPT	pathwayBased	0.1192196055555	16	267412	5703
qHTS Assay for Tau Filament Binding	leukocyte count	MAPT	targetBased	0.1192196055555	16	69668	1391
qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization	leukocyte count	MAPT	pathwayBased	0.1192196055555	16	271402	1048
AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of microphthalmia-associated transcription factor (MITF)	leukocyte count	MITF inhibitors	targetBased	0.384700951597661	4	642362	5830
MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Inhibitor_SinglePoint_HTS_Activity	leukocyte count	MITF	targetBased	0.384700951597661	4	331360	2760
Alphascreen assay for small molecules abrogating mHTT-CaM Interaction	leukocyte count	HTT	targetBased	0.404183756146959	12	189882	6790
Primary qHTS for Identification of Small Molecule Inhibitors of Huntingtin Promoter Activity	leukocyte count	HTT	targetBased	0.404183756146959	12	48068	449
qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Aggregate Formation (GFP)	leukocyte count	HTT	targetBased	0.404183756146959	12	220571	2380
qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Cytoprotection (ATP)	leukocyte count	HTT	targetBased	0.404183756146959	12	223611	305
Primary qHTS for Inhibitors of ATXN expression	leukocyte count	ATXN2_repressors	targetBased	0.34521557684426	48	358434	2554
Primary HTS Assay for S1P3 Antagonists	leukocyte count	S1PR3	targetBased	0.516140572346041	39	169141	462
qHTS for Inhibitors of Vif-A3G Interactions: qHTS	leukocyte count	APOBEC3G_inhibitors	targetBased	0.163592713138845	19	402348	311
uHTS identification of APOBEC3G DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay	leukocyte count	APOBEC3G_inhibitors	targetBased	0.163592713138845	19	331753	931
Primary Cell-Based High-Throughput Screening to Identify Agonists of the Sphingosine 1-phosphate receptor 2 (S1P2)	leukocyte count	S1PR2	targetBased	0.540782639544795	27	96879	447
Primary Cell-Based High-Throughput Screening to Identify Antagonists of the Sphingosine 1-phosphate receptor 2 (S1P2)	leukocyte count	S1PR2	targetBased	0.540782639544795	27	96879	207
USP28 deubiquitinase inhibition: Primary qHTS	platelet count	USP28	targetBased	0.313250586102811	6	47480	1413
Primary cell-based high-throughput screening assay for identification of compounds that inhibit KCNQ1 potassium channels	platelet count	KCNQ1	targetBased	0.376485055941741	5	305610	3878
Primary cell-based high-throughput screening assay for identification of compounds that potentiate/activate KCNQ1 potassium channels	platelet count	KCNQ1	targetBased	0.376485055941741	5	305610	1082
High Content Assay for Compounds that inhibit the Assembly of the Perinucleolar Compartment	hematocrit	PTBP1	targetBased	0.410430557226749	12	139718	4338
Primary Cell-based High Throughput Screening assay for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA)	hematocrit	RORA	pathwayBased	0.37936183548857	6	64908	979
Primary Cell-based High Throughput Screening assay for inhibitors of the Retinoic Acid Receptor-related orphan receptor A (RORA)	hematocrit	RORA	pathwayBased	0.37936183548857	6	64908	278
HTS to identify compounds that promote myeloid differentiation with MLPCN compound set	platelet count	HOXA9	pathwayBased	0.328514227267665	8	358556	3721
qHTS for Agonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1): primary screen	platelet count	RAPGEF3	targetBased	0.10269139483973	6	364614	268
qHTS for Antagonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1): primary screen	platelet count	RAPGEF3	targetBased	0.10269139483973	6	364614	517
uHTS identification of small molecule inhibitors of the catalytic domain of the SUMO protease, SENP1 in a FRET assay	platelet count	SENP1	targetBased	0.155616223658663	5	363840	774
qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS	platelet count	GNAS	targetBased	0.173342261990193	5	334825	423
qHTS for Antagonists of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS	platelet count	GNAS	targetBased	0.173342261990193	5	337446	1356
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	platelet count	JAK2	targetBased	0.781132669160644	77	217959	2390
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of the interaction of the Ras and Rab interactor 1 protein (Rin1) and the c-abl oncogene 1, non-receptor tyrosine kinase (Abl)	platelet count	ABL1_interaction	targetBased	0.365052310125582	5	359207	1432
qHTS for Inhibitors of TGF-b	platelet count	TGFB1	pathwayBased	0.321703129646884	9	403345	4970
Toxoplasma gondii inhibition HTS in the presence of IFN-y	platelet count	IFNG	targetBased	0.464969406779466	9	67275	2509
uHTS identification of HIF-2a Inhibitors in a luminesence assay	platelet count	HIF-2a_inhibitors	targetBased	0.119487686061057	6	363840	2624
uHTS for the identification of compounds that potentiate TRAIL-induced apoptosis of cancer cells	platelet count	TNFSF10	targetBased	0.460595698389677	14	217035	883
qHTS for Inhibitors of Polymerase Kappa	platelet count	POLK	targetBased	0.130045194305764	6	395295	2034
qHTS Assay for Inhibitors of BAZ2B	platelet count	BAZ2B_modulators	targetBased	0.364490242201112	6	356826	15709
Luminescence-based cell-based primary high throughput screening assay to identify inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3)	platelet count	NCOA3	targetBased	0.384142714120174	6	359207	620
HTS to identify compounds that promote myeloid differentiation with MLPCN compound set	hematocrit	HOXA9	pathwayBased	0.251479569665018	5	358556	3721
uHTS identification of small molecule inhibitors of the catalytic domain of the SUMO protease, SENP1 in a FRET assay	hematocrit	SENP1	targetBased	0.24098495936812	17	363840	774
Identification of Molecular Probes that Activate MRP-1	hematocrit	ABCC1_activators	targetBased	0.362033856039168	8	138717	842
Toxoplasma gondii inhibition HTS in the presence of IFN-y	hematocrit	IFNG	targetBased	0.103241060160023	122	67275	2509
uHTS identification of HIF-2a Inhibitors in a luminesence assay	hematocrit	HIF-2a_inhibitors	targetBased	0.507214442929743	62	363840	2624
Nrf2 qHTS screen for inhibitors	hematocrit	nrf2Inhibitors	targetBased	0.118282948915954	11	360873	7438
qHTS of Nrf2 Activators	hematocrit	Nrf2 activators	pathwayBased	0.118282948915954	11	403871	1243
uHTS for the identification of compounds that potentiate TRAIL-induced apoptosis of cancer cells	hematocrit	TNFSF10	targetBased	0.389870263072986	8	217035	883
Fluorescence-based biochemical high throughput primary assay to identify inhibitors of phospholipase C isozymes (PLC-gamma1).	hematocrit	PLCG1	targetBased	0.231003994738942	6	369953	3123
HTS for PAX8 inhibitors using PAX8 luciferase reporter gene assay in RMG-I cells Measured in Cell-Based System Using Plate Reader - 7054-01_Inhibitor_SinglePoint_HTS_Activity	hematocrit	PAX8	targetBased	0.262420101884231	8	353950	4145
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	hematocrit	PPARG	targetBased	0.490999255387841	18	99314	335
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	hematocrit	PPARG	targetBased	0.490999255387841	18	196176	782
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	hematocrit	PPARG	targetBased	0.490999255387841	18	99314	390
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	hematocrit	PPARG	targetBased	0.490999255387841	18	196177	811
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	hematocrit	PPARG	targetBased	0.490999255387841	18	196176	670
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	hematocrit	PPARG	targetBased	0.490999255387841	18	196177	519
Fluorescence-based biochemical primary high throughput screening assay to identify activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF)	platelet count	TNNI3	targetBased	0.378895417419146	12	335239	801
Fluorescence-based biochemical primary high throughput screening assay to identify inhibitors of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF)	platelet count	TNNI3	targetBased	0.378895417419146	12	335238	390
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	platelet count	PPARG	targetBased	0.401604230111622	18	99314	335
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	platelet count	PPARG	targetBased	0.401604230111622	18	196176	782
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	platelet count	PPARG	targetBased	0.401604230111622	18	99314	390
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	platelet count	PPARG	targetBased	0.401604230111622	18	196177	811
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	platelet count	PPARG	targetBased	0.401604230111622	18	196176	670
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	platelet count	PPARG	targetBased	0.401604230111622	18	196177	519
USP30 deubiquitinase inhibition: Primary qHTS	platelet count	USP30	targetBased	0.363025971761201	9	47480	2500
SSB-PriA antibiotic resistant target AlphaScreen	platelet count	Klebsiella pneumoniaÃ‚Â SSB-PriAÃ‚Â interaction	targetBased	0.104732938974474	6	431236	2568
uHTS Luminescent assay for identification of inhibitors of Sentrin-specific protease 7 (SENP7)	platelet count	SENP7	targetBased	0.390165816960589	9	331670	4902
Luminescence-based cell-based primary high throughput screening assay to identify inhibitors of the Steroid Receptor Coactivator 2 (SRC2; NCOA2)	platelet count	NCOA2	targetBased	0.352889344907773	5	368927	620
Fluorescence polarization-based biochemical primary high throughput screening assay to identify activators of the Protein Kinase A-R2B (PKA-R2B) complex	platelet count	PRKACB	targetBased	0.284394305082485	6	343468	273
HTS Discovery of Chemical Inhibitors of HePTP, a Leukemia Target	platelet count	PTPN7	targetBased	0.224118162050272	5	112381	724
qHTS Assay for Identifying a Potential Treatment of Ataxia-Telangiectasia	platelet count	ATM_modulators	targetBased	0.219241830968862	14	322361	619
High throughput discovery of novel modulators of ROMK K+ channel activity: Primary Screen	platelet count	KCNJ1	targetBased	0.164361388391418	8	125268	2463
Luminescence Cell-Based Primary HTS to Identify Inhibitors of A1 Apoptosis.	platelet count	BCL2L11_inhibitors	targetBased	0.476803768188648	24	325630	216
uHTS Fluorescent assay for identification of inhibitors of hexokinase domain containing I (HKDC1)	platelet count	HKDC1	targetBased	0.377344066993692	6	340696	540
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb via a fluorescence resonance energy transfer (FRET) assay.	platelet count	RUNX1	targetBased	0.48599177170108	42	215667	993
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay.	platelet count	RUNX1	targetBased	0.48599177170108	42	218234	1620
Inhibitors of USP1/UAF1: Primary Screen	platelet count	USP1	targetBased	0.102280976890784	6	389569	904
uHTS Luminescent assay for identification of inhibitors of NALP3 in yeast	platelet count	NLRP3	targetBased	0.503196509516558	9	330392	1295
HTS for Estrogen Receptor-beta Coactivator Binding inhibitors	hematocrit	ESR2_inhibitors	targetBased	0.539606154049657	12	86095	1114
qHTS assay to identify small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway	hematocrit	RORCgammaPathwayInhibitors	pathwayBased	0.103114813849328	8	7671	874
VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity	hematocrit	RORC	targetBased	0.103114813849328	8	304060	10600
qHTS for inhibitors of ROR gamma transcriptional activity	hematocrit	RORCgammaPathwayInhibitors	pathwayBased	0.103114813849328	8	305439	16717
Fluorescence-based biochemical high throughput primary assay to identify inhibitors of phospholipase C isozymes (PLC-beta3).	hematocrit	PLCB3	targetBased	0.128133931942342	6	369953	662
Luminescence Cell-Based Primary HTS to Identify Inhibitors of A1 Apoptosis.	hematocrit	BCL2L11_inhibitors	targetBased	0.393662605812907	15	325630	216
uHTS Fluorescent assay for identification of inhibitors of hexokinase domain containing I (HKDC1)	hematocrit	HKDC1	targetBased	0.402981247843091	20	340696	540
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb via a fluorescence resonance energy transfer (FRET) assay.	hematocrit	RUNX1	targetBased	0.238060179589518	6	215667	993
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay.	hematocrit	RUNX1	targetBased	0.238060179589518	6	218234	1620
HTS of Smad transcription factor inhibitors	hematocrit	SMAD3	targetBased	0.341595813275946	9	88033	251
MLPCN ERAP1 Measured in Biochemical System Using Plate Reader - 7016-01_Inhibitor_SinglePoint_HTS_Activity	platelet count	ERAP1_inhibitors	targetBased	0.433981650795316	9	335777	499
Primary biochemical high-throughput screening assay to measure P97 ATPase inhibition	platelet count	VCP	targetBased	0.406914312836503	8	217959	923
qHTS Assay for Activators of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease	platelet count	GAA	targetBased	0.401202555703761	9	199169	715
qHTS Assay for Inhibitors and Activators of Human alpha-Glucosidase Cleavage of Glycogen	platelet count	GAA_inhibitors	targetBased	0.401202555703761	9	302297	1165
Primary biochemical high throughput screening assay to identify inhibitors of BCL2-related protein, long isoform (BCLXL).	platelet count	BCL2L1_modulators	targetBased	0.503049386602255	26	314998	2199
Luminescence-based primary cell-based high throughput screening assay to identify activators of the Aryl Hydrocarbon Receptor (AHR)	albuminuria	AHR_activators	targetBased	0.330562688114048	4	324747	7988
uHTS identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay	platelet count	UBE2N	targetBased	0.470604027393644	14	330393	1538
qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding	platelet count	MAPT	pathwayBased	0.378215498418705	5	267412	5703
qHTS Assay for Tau Filament Binding	platelet count	MAPT	targetBased	0.378215498418705	5	69668	1391
qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization	platelet count	MAPT	pathwayBased	0.378215498418705	5	271402	1048
AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of microphthalmia-associated transcription factor (MITF)	platelet count	MITF inhibitors	targetBased	0.513483389362432	9	642362	5830
MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Inhibitor_SinglePoint_HTS_Activity	platelet count	MITF	targetBased	0.513483389362432	9	331360	2760
Alphascreen assay for small molecules abrogating mHTT-CaM Interaction	platelet count	HTT	targetBased	0.291976673271679	6	189882	6790
Primary qHTS for Identification of Small Molecule Inhibitors of Huntingtin Promoter Activity	platelet count	HTT	targetBased	0.291976673271679	6	48068	449
qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Aggregate Formation (GFP)	platelet count	HTT	targetBased	0.291976673271679	6	220571	2380
qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Cytoprotection (ATP)	platelet count	HTT	targetBased	0.291976673271679	6	223611	305
Primary qHTS for Inhibitors of ATXN expression	platelet count	ATXN2_repressors	targetBased	0.411033584612215	59	358434	2554
Primary HTS Assay for S1P3 Antagonists	platelet count	S1PR3	targetBased	0.468786522828054	24	169141	462
Primary Cell-Based High-Throughput Screening to Identify Agonists of the Sphingosine 1-phosphate receptor 2 (S1P2)	platelet count	S1PR2	targetBased	0.161791839489869	5	96879	447
Primary Cell-Based High-Throughput Screening to Identify Antagonists of the Sphingosine 1-phosphate receptor 2 (S1P2)	platelet count	S1PR2	targetBased	0.161791839489869	5	96879	207
HTS for Identification of VLA-4 Allosteric Modulators from MLPCN library	leukocyte count	ITGA4	targetBased	0.560601777458065	76	326888	645
Primary Cell-Based Assay to Identify Agonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	leukocyte count	S1PR4	targetBased	0.720998711707685	68	217959	771
Primary Cell-Based Assay to Identify Antagonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	leukocyte count	S1PR4	targetBased	0.720998711707685	68	217959	569
qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding	hematocrit	MAPT	pathwayBased	0.246227113169751	17	267412	5703
qHTS Assay for Tau Filament Binding	hematocrit	MAPT	targetBased	0.246227113169751	17	69668	1391
qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization	hematocrit	MAPT	pathwayBased	0.246227113169751	17	271402	1048
AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of microphthalmia-associated transcription factor (MITF)	hematocrit	MITF inhibitors	targetBased	0.512591213709501	11	642362	5830
MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Inhibitor_SinglePoint_HTS_Activity	hematocrit	MITF	targetBased	0.512591213709501	11	331360	2760
Primary qHTS for Inhibitors of ATXN expression	hematocrit	ATXN2_repressors	targetBased	0.394260484123987	23	358434	2554
Luminescence-based cell-based high throughput primary screening assay to identify agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3)	hematocrit	NR2E3	targetBased	0.262279059467034	6	362026	1281
TR-FRET-based primary biochemical high throughput screening assay to identify agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3).	hematocrit	NR2E3	targetBased	0.262279059467034	6	314998	380
Identification of CBX7 inhibitors - Primary Alpha Screen	hematocrit	Chromobox protein homolog 7 inhibitors	targetBased	0.33184602051689	5	64999	724
Luminescence-based cell-based primary high throughput screening assay to identify inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2)	hematocrit	NR5A2	targetBased	0.496582443933914	6	363803	458
qHTS Assay to Identify Small Molecule Activators of BRCA1 Expression	complete blood cell count	BRCA1 activation	pathwayBased	0.110237034306894	114	376029	3978
qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS	complete blood cell count	GNAS	targetBased	0.106580045261337	4	334825	423
qHTS for Antagonists of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS	complete blood cell count	GNAS	targetBased	0.106580045261337	4	337446	1356
qHTS of IL-2 Activators	complete blood cell count	IL2	targetBased	0.118980122687084	12	364617	238
Luminescence-based cell-based primary high throughput screening assay to identify inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3)	complete blood cell count	NCOA3	targetBased	0.135079887501143	4	359207	620
E3 Ligase HTS_1536	complete blood cell count	MDM2	targetBased	0.164557594114351	6	207811	220
qHTS Assay for Identifying a Potential Treatment of Ataxia-Telangiectasia	complete blood cell count	ATM_modulators	targetBased	0.213142702699286	58	322361	619
qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding	complete blood cell count	MAPT	pathwayBased	0.155989182838022	23	267412	5703
qHTS Assay for Tau Filament Binding	complete blood cell count	MAPT	targetBased	0.155989182838022	23	69668	1391
qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization	complete blood cell count	MAPT	pathwayBased	0.155989182838022	23	271402	1048
HTS for developing T Cell Immune Modulators	lymphocyte count	ITGAL	targetBased	0.452946733395186	20	326271	221
Fluorescence-based primary biochemical high throughput screening assay to identify inhibitors of Protein Phosphatase 5 (PP5).	lymphocyte count	PPP5C	targetBased	0.36537295818237	6	314999	564
HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Inhibitor_SinglePoint_HTS_Activity	lymphocyte count	SCARB1	targetBased	0.453931817478268	5	319204	3065
HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Activator_SinglePoint_HTS_Activity	lymphocyte count	SCARB1	targetBased	0.453931817478268	5	316970	306
HTS of Estrogen Receptor- alpha Coactivator Binding inhibitors	lymphocyte count	ESR1_inhibitors	targetBased	0.148112612404623	8	86095	1442
HTS of Estrogen Receptor- alpha Coactivator Binding Potentiators	lymphocyte count	ESR1_modulators	targetBased	0.148112612404623	8	86095	1151
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of the interaction of the Ras and Rab interactor 1 protein (Rin1) and the c-abl oncogene 1, non-receptor tyrosine kinase (Abl)	lymphocyte count	ABL1_interaction	targetBased	0.376119457498326	6	359207	1432
Identification of CBX7 inhibitors - Primary Alpha Screen	lymphocyte count	Chromobox protein homolog 7 inhibitors	targetBased	0.462433921575717	12	64999	724
qHTS Assay for Inhibitors of the CtBP/E1A Interaction	lymphocyte count	RBBP8	targetBased	0.369846442019323	7	335214	1652
Identification of Molecular Probes that Activate MRP-1	lymphocyte count	ABCC1_activators	targetBased	0.477649473479832	5	138717	842
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype	lymphocyte count	RAB2A	targetBased	0.365470255721534	5	194628	365
Primary qHTS assay for inhibitors of human arachidonate 12S-lipoxygenase (ALOX12): Round 2	lymphocyte count	ALOX12_inhibitors	targetBased	0.216243774290931	4	564288	6030
High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Primary Screen	lymphocyte count	NFKB1	pathwayBased	0.468569299477128	17	193265	3100
uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay	lymphocyte count	NFKB1	pathwayBased	0.468569299477128	17	359244	3094
Toxoplasma gondii inhibition HTS in the presence of IFN-y	lymphocyte count	IFNG	targetBased	0.466456541402755	6	67275	2509
HTS for Identification of VLA-4 Allosteric Modulators from MLPCN library	lymphocyte count	ITGA4	targetBased	0.552482559460344	41	326888	645
High Content Assay for Compounds that inhibit the Assembly of the Perinucleolar Compartment	C-reactive protein measurement	PTBP1	targetBased	0.330448450993928	5	139718	4338
Primary Cell-based High Throughput Screening assay for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA)	C-reactive protein measurement	RORA	pathwayBased	0.329670899464705	14	64908	979
Primary Cell-based High Throughput Screening assay for inhibitors of the Retinoic Acid Receptor-related orphan receptor A (RORA)	C-reactive protein measurement	RORA	pathwayBased	0.329670899464705	14	64908	278
HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Inhibitor_SinglePoint_HTS_Activity	C-reactive protein measurement	SCARB1	targetBased	0.45695928662431	5	319204	3065
HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Activator_SinglePoint_HTS_Activity	C-reactive protein measurement	SCARB1	targetBased	0.45695928662431	5	316970	306
ROC1-CUL1 CTD Inhibitor di-Ub FRET Primary HTS Screen	C-reactive protein measurement	RBX1	targetBased	0.156213928034159	6	143816	859
Nrf2 qHTS screen for inhibitors	C-reactive protein measurement	nrf2Inhibitors	targetBased	0.426257661351693	5	360873	7438
qHTS of Nrf2 Activators	C-reactive protein measurement	Nrf2 activators	pathwayBased	0.426257661351693	5	403871	1243
Screen for inhibitors of the SWI/SNF chromatin remodeling complex (esBAF) in mouse embryonic stem cells with Luciferase reporter assay Measured in Cell-Based System Using Plate Reader - 2141-01_Inhibitor_SinglePoint_HTS_Activity	C-reactive protein measurement	SMARCA4	targetBased	0.182839864718117	5	344733	7043
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac activated mutant	C-reactive protein measurement	RAC1	targetBased	0.157073057949157	5	194629	219
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac wildtype	C-reactive protein measurement	RAC1	targetBased	0.157073057949157	5	194628	521
MLPCN SirT-5 Measured in Biochemical System Using Imaging - 7044-01_Inhibitor_SinglePoint_HTS_Activity_Set5	lymphocyte count	SIRT5	targetBased	0.326772109946808	9	323507	3752
HTS for PAX8 inhibitors using PAX8 luciferase reporter gene assay in RMG-I cells Measured in Cell-Based System Using Plate Reader - 7054-01_Inhibitor_SinglePoint_HTS_Activity	lymphocyte count	PAX8	targetBased	0.104772998980367	8	353950	4145
Primary Cell-Based Assay to Identify Agonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	lymphocyte count	S1PR4	targetBased	0.498970057580923	7	217959	771
Primary Cell-Based Assay to Identify Antagonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	lymphocyte count	S1PR4	targetBased	0.498970057580923	7	217959	569
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	lymphocyte count	PPARG	targetBased	0.417805158839386	14	99314	335
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	lymphocyte count	PPARG	targetBased	0.417805158839386	14	196176	782
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	lymphocyte count	PPARG	targetBased	0.417805158839386	14	99314	390
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	lymphocyte count	PPARG	targetBased	0.417805158839386	14	196177	811
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	lymphocyte count	PPARG	targetBased	0.417805158839386	14	196176	670
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	lymphocyte count	PPARG	targetBased	0.417805158839386	14	196177	519
Primary biochemical high-throughput screening assay for inhibitors of Rho kinase 2 (Rhok2)	lymphocyte count	ROCK2	targetBased	0.412557613054243	8	59788	212
Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bfl-1	lymphocyte count	BCL2A1_modulators	targetBased	0.402558964917309	5	194826	237
Luminescence-based cell-based primary high throughput screening assay to identify inhibitors of the Steroid Receptor Coactivator 2 (SRC2; NCOA2)	lymphocyte count	NCOA2	targetBased	0.35250837730816	5	368927	620
qHTS Assay for Identifying a Potential Treatment of Ataxia-Telangiectasia	lymphocyte count	ATM_modulators	targetBased	0.510858872706143	13	322361	619
Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2	lymphocyte count	THRB	targetBased	0.413880773347188	6	276265	806
uHTS identification of small molecule inhibitors of Artemis endonuclease activity via a fluorescence intensity assay	lymphocyte count	artemis_inhibitors	targetBased	0.412441851828701	8	30104	235
Luminescence Cell-Based Primary HTS to Identify Inhibitors of A1 Apoptosis.	lymphocyte count	BCL2L11_inhibitors	targetBased	0.493713832083047	33	325630	216
uHTS Fluorescent assay for identification of inhibitors of hexokinase domain containing I (HKDC1)	lymphocyte count	HKDC1	targetBased	0.499930744691461	13	340696	540
HTS identification of compounds inhibiting the binding of CD11b/CD18 to fibrinogen via a luminescence assay.	lymphocyte count	ITGB2	targetBased	0.449679900237226	11	92518	501
Primary HTS assay for chemical inhibitors of TNF alpha stimulated VCAM1 expression	lymphocyte count	VCAM1_expression	targetBased	0.52226432746613	21	94498	457
uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (PABP)	mean corpuscular hemoglobin	PABPC1	targetBased	0.298695498484635	5	290915	2982
uHTS identification of microRNA-mediated mRNA deadenylation inhibitors by fluoresence polarization assay	mean corpuscular hemoglobin	PABPC1	targetBased	0.298695498484635	5	359244	1307
HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Inhibitor_SinglePoint_HTS_Activity	mean corpuscular hemoglobin	SCARB1	targetBased	0.452343353114931	5	319204	3065
HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Activator_SinglePoint_HTS_Activity	mean corpuscular hemoglobin	SCARB1	targetBased	0.452343353114931	5	316970	306
HTS to identify compounds that promote myeloid differentiation with MLPCN compound set	mean corpuscular hemoglobin	HOXA9	pathwayBased	0.357453568887197	6	358556	3721
qHTS for Agonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1): primary screen	mean corpuscular hemoglobin	RAPGEF3	targetBased	0.209994179420903	6	364614	268
qHTS for Antagonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1): primary screen	mean corpuscular hemoglobin	RAPGEF3	targetBased	0.209994179420903	6	364614	517
HTS Assay for Peg3 Promoter Inhibitors	mean corpuscular hemoglobin	PPP1R15A	targetBased	0.37960776007004	5	359244	6145
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	mean corpuscular hemoglobin	JAK2	targetBased	0.372570966042536	21	217959	2390
Identification of Molecular Probes that Activate MRP-1	mean corpuscular hemoglobin	ABCC1_activators	targetBased	0.490286294928167	8	138717	842
High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Primary Screen	mean corpuscular hemoglobin	NFKB1	pathwayBased	0.430368497391276	6	193265	3100
uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay	mean corpuscular hemoglobin	NFKB1	pathwayBased	0.430368497391276	6	359244	3094
uHTS identification of Caspase-8 TRAIL sensitizers in a luminesence assay	mean corpuscular hemoglobin	TNFRSF10B	targetBased	0.318018713053894	5	363840	3764
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of 5-meCpG-binding domain protein 2 (MBD2)-DBD binding to methylated oligonucleotide	mean corpuscular hemoglobin	MBD2	targetBased	0.391941406050785	6	369953	1149
qHTS assay to identify small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway	C-reactive protein measurement	RORCgammaPathwayInhibitors	pathwayBased	0.164688110176193	5	7671	874
VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity	C-reactive protein measurement	RORC	targetBased	0.164688110176193	5	304060	10600
qHTS for inhibitors of ROR gamma transcriptional activity	C-reactive protein measurement	RORCgammaPathwayInhibitors	pathwayBased	0.164688110176193	5	305439	16717
Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2	C-reactive protein measurement	THRB	targetBased	0.475895429341828	5	276265	806
uHTS of small molecular inhibitors for p47phox, a regulatory protein of NADPH oxidases (Noxs)	C-reactive protein measurement	p47phoxInhibitors	targetBased	0.221328667087177	5	217454	1142
uHTS identification of TNAP inhibitors in the absence of phosphate acceptor performed in luminescent assay	C-reactive protein measurement	ALPL_inhibitors	targetBased	0.44677483775825	5	195560	517
uHTS Luminescent assay for identification of inhibitors of NALP3 in yeast	C-reactive protein measurement	NLRP3	targetBased	0.589598524652379	30	330392	1295
Luminescence-based cell-based primary high throughput screening assay to identify biased ligands of the melanocortin 4 receptor (MC4R): agonists of MC4R	C-reactive protein measurement	MC4R	targetBased	0.509064091101982	9	356160	3470
TRFRET-based cell-based primary high throughput screening assay to identify biased ligands of the melanocortin 4 receptor (MC4R): antagonists of MC4R	C-reactive protein measurement	MC4R	targetBased	0.509064091101982	9	356160	1703
uHTS Luminescent assay for identification of inhibitors of Sentrin-specific protease 7 (SENP7)	mean corpuscular hemoglobin	SENP7	targetBased	0.291172065293046	8	331670	4902
qHTS Assay for NPC1 Promoter Activators	mean corpuscular hemoglobin	NPC1	pathwayBased	0.365807610509874	9	320682	7575
qHTS assay for re-activators of p53 using a Luc reporter	mean corpuscular hemoglobin	TP53	pathwayBased	0.245623452736891	5	321427	201
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Nonpermissive Temperature	mean corpuscular hemoglobin	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.245623452736891	5	54509	528
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Permissive Temperature	mean corpuscular hemoglobin	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.245623452736891	5	54513	338
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature	mean corpuscular hemoglobin	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.245623452736891	5	125394	1890
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Permissive Temperature	mean corpuscular hemoglobin	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.245623452736891	5	124022	1156
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of myeloid cell leukemia sequence 1 (MCL1) interactions with BIM-BH3 peptide.	mean corpuscular hemoglobin	MCL1	targetBased	0.206264257716773	5	314998	2139
uHTS of Mcl-1/Bid interaction inhibitors	mean corpuscular hemoglobin	MCL1	targetBased	0.206264257716773	5	218602	2129
uHTS of Mcl-1/Noxa interaction inhibitors	mean corpuscular hemoglobin	MCL1	targetBased	0.206264257716773	5	217330	3334
Inhibitors of CDC25B-CDK2/CyclinA interaction	mean corpuscular hemoglobin	Inhibitors of CDC25B-CDK2/CyclinA interaction	targetBased	0.381873304057332	12	93798	679
qHTS Assay for Identifying a Potential Treatment of Ataxia-Telangiectasia	mean corpuscular hemoglobin	ATM_modulators	targetBased	0.12194008955461	12	322361	619
Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2	mean corpuscular hemoglobin	THRB	targetBased	0.527919870832325	21	276265	806
Luminescence Cell-Based Primary HTS to Identify Inhibitors of A1 Apoptosis.	mean corpuscular hemoglobin	BCL2L11_inhibitors	targetBased	0.441911556758352	38	325630	216
uHTS Fluorescent assay for identification of inhibitors of hexokinase domain containing I (HKDC1)	mean corpuscular hemoglobin	HKDC1	targetBased	0.437520478812388	9	340696	540
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb via a fluorescence resonance energy transfer (FRET) assay.	mean corpuscular hemoglobin	RUNX1	targetBased	0.285244413762737	9	215667	993
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay.	mean corpuscular hemoglobin	RUNX1	targetBased	0.285244413762737	9	218234	1620
Inhibitors of USP1/UAF1: Primary Screen	mean corpuscular hemoglobin	USP1	targetBased	0.284647886399954	8	389569	904
qHTS Assay for Activators of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease	mean corpuscular hemoglobin	GAA	targetBased	0.328296685599632	6	199169	715
qHTS Assay for Inhibitors and Activators of Human alpha-Glucosidase Cleavage of Glycogen	mean corpuscular hemoglobin	GAA_inhibitors	targetBased	0.328296685599632	6	302297	1165
qHTS screen for small molecules that induce genotoxicity in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1	mean corpuscular hemoglobin	ATAD5_inhibitors	targetBased	0.241387583646705	5	330109	4174
qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1	mean corpuscular hemoglobin	ATAD5_inhibitors	targetBased	0.241387583646705	5	330107	7652
Fluorescence-based primary biochemical high throughput screening assay to identify inhibitors of human diacylglycerol lipase, beta (DAGLB)	lymphocyte count	DAGLB_inhibitors	targetBased	0.472640458180406	13	343468	202
CYP2C19 Assay	lymphocyte count	CYP2C19_inhibitors	targetBased	0.370985738057349	5	95857	20295
HTS for Beta-2AR agonists via FAP method	lymphocyte count	ADRB2_activators	targetBased	0.17511806540511	5	339297	1446
uHTS identification of small molecule antagonists of the EBI2 receptor via a luminescent beta-arrestin assay	lymphocyte count	GPR183	targetBased	0.339637152660564	7	363840	2946
Primary HTS and Confirmation Assays for S1P1 Agonists and Agonism Potentiators	lymphocyte count	S1PR1	targetBased	0.583691959694125	53	55710	315
qHTS screen for small molecules that induce genotoxicity in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1	lymphocyte count	ATAD5_inhibitors	targetBased	0.167258509975451	6	330109	4174
qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1	lymphocyte count	ATAD5_inhibitors	targetBased	0.167258509975451	6	330107	7652
qHTS Assay for the Inhibitors of L3MBTL1	lymphocyte count	L3MBTL1	targetBased	0.189013721969915	5	225309	1492
Primary qHTS for Inhibitors of ATXN expression	lymphocyte count	ATXN2_repressors	targetBased	0.389323343097047	23	358434	2554
Primary HTS Assay for S1P3 Antagonists	lymphocyte count	S1PR3	targetBased	0.46250511634025	18	169141	462
uHTS identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay	mean corpuscular hemoglobin	UBE2N	targetBased	0.278090876926247	9	330393	1538
Primary qHTS for Inhibitors of ATXN expression	mean corpuscular hemoglobin	ATXN2_repressors	targetBased	0.280937217471921	6	358434	2554
FRET-based HTS for detection of RAD52 Inhibitors Measured in Biochemical System Using Plate Reader - 7018-01_Inhibitor_SinglePoint_HTS_Activity_Set2	mean corpuscular hemoglobin concentration	RAD52	targetBased	0.414049142800529	5	352074	1608
HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Inhibitor_SinglePoint_HTS_Activity	mean corpuscular hemoglobin concentration	SCARB1	targetBased	0.4579501851685	5	319204	3065
HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Activator_SinglePoint_HTS_Activity	mean corpuscular hemoglobin concentration	SCARB1	targetBased	0.4579501851685	5	316970	306
HTS to identify compounds that promote myeloid differentiation with MLPCN compound set	mean corpuscular hemoglobin concentration	HOXA9	pathwayBased	0.388602681533098	5	358556	3721
qHTS for Agonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1): primary screen	mean corpuscular hemoglobin concentration	RAPGEF3	targetBased	0.207472523662331	6	364614	268
qHTS for Antagonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1): primary screen	mean corpuscular hemoglobin concentration	RAPGEF3	targetBased	0.207472523662331	6	364614	517
uHTS identification of small molecule inhibitors of the catalytic domain of the SUMO protease, SENP1 in a FRET assay	mean corpuscular hemoglobin concentration	SENP1	targetBased	0.156043745565287	9	363840	774
HTS Assay for Peg3 Promoter Inhibitors	mean corpuscular hemoglobin concentration	PPP1R15A	targetBased	0.382151379675624	5	359244	6145
Primary Cell-based High Throughput Screening assay for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA)	serum albumin measurement	RORA	pathwayBased	0.283686778125948	5	64908	979
Primary Cell-based High Throughput Screening assay for inhibitors of the Retinoic Acid Receptor-related orphan receptor A (RORA)	serum albumin measurement	RORA	pathwayBased	0.283686778125948	5	64908	278
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	serum albumin measurement	PPARG	targetBased	0.442604773594403	5	99314	335
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	serum albumin measurement	PPARG	targetBased	0.442604773594403	5	196176	782
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	serum albumin measurement	PPARG	targetBased	0.442604773594403	5	99314	390
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	serum albumin measurement	PPARG	targetBased	0.442604773594403	5	196177	811
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	serum albumin measurement	PPARG	targetBased	0.442604773594403	5	196176	670
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	serum albumin measurement	PPARG	targetBased	0.442604773594403	5	196177	519
qHTS for Inhibitors of Vif-A3G Interactions: qHTS	lymphocyte count	APOBEC3G_inhibitors	targetBased	0.321209645427089	9	402348	311
uHTS identification of APOBEC3G DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay	lymphocyte count	APOBEC3G_inhibitors	targetBased	0.321209645427089	9	331753	931
Primary Cell-Based High-Throughput Screening to Identify Agonists of the Sphingosine 1-phosphate receptor 2 (S1P2)	lymphocyte count	S1PR2	targetBased	0.389563394320064	8	96879	447
Primary Cell-Based High-Throughput Screening to Identify Antagonists of the Sphingosine 1-phosphate receptor 2 (S1P2)	lymphocyte count	S1PR2	targetBased	0.389563394320064	8	96879	207
Identification of Molecular Probes that Activate MRP-1	mean corpuscular hemoglobin concentration	ABCC1_activators	targetBased	0.531552989154815	14	138717	842
High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Primary Screen	mean corpuscular hemoglobin concentration	NFKB1	pathwayBased	0.400185706432509	5	193265	3100
uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay	mean corpuscular hemoglobin concentration	NFKB1	pathwayBased	0.400185706432509	5	359244	3094
uHTS identification of HIF-2a Inhibitors in a luminesence assay	mean corpuscular hemoglobin concentration	HIF-2a_inhibitors	targetBased	0.221089192527785	11	363840	2624
Fluorescence-based biochemical high throughput primary assay to identify inhibitors of phospholipase C isozymes (PLC-gamma1).	mean corpuscular hemoglobin concentration	PLCG1	targetBased	0.284375273167534	5	369953	3123
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	mean corpuscular hemoglobin concentration	PPARG	targetBased	0.430996617021105	11	99314	335
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	mean corpuscular hemoglobin concentration	PPARG	targetBased	0.430996617021105	11	196176	782
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	mean corpuscular hemoglobin concentration	PPARG	targetBased	0.430996617021105	11	99314	390
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	mean corpuscular hemoglobin concentration	PPARG	targetBased	0.430996617021105	11	196177	811
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	mean corpuscular hemoglobin concentration	PPARG	targetBased	0.430996617021105	11	196176	670
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	mean corpuscular hemoglobin concentration	PPARG	targetBased	0.430996617021105	11	196177	519
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of 5-meCpG-binding domain protein 2 (MBD2)-DBD binding to methylated oligonucleotide	mean corpuscular hemoglobin concentration	MBD2	targetBased	0.396132961685247	5	369953	1149
Primary qHTS for Inhibitors of ATXN expression	serum albumin measurement	ATXN2_repressors	targetBased	0.358678377541643	6	358434	2554
HTS of Estrogen Receptor- alpha Coactivator Binding inhibitors	total blood protein measurement	ESR1_inhibitors	targetBased	0.434277490987837	5	86095	1442
HTS of Estrogen Receptor- alpha Coactivator Binding Potentiators	total blood protein measurement	ESR1_modulators	targetBased	0.434277490987837	5	86095	1151
High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Primary Screen	total blood protein measurement	NFKB1	pathwayBased	0.465496619760037	5	193265	3100
uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay	total blood protein measurement	NFKB1	pathwayBased	0.465496619760037	5	359244	3094
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	total blood protein measurement	PPARG	targetBased	0.446100866506194	6	99314	335
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	total blood protein measurement	PPARG	targetBased	0.446100866506194	6	196176	782
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	total blood protein measurement	PPARG	targetBased	0.446100866506194	6	99314	390
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	total blood protein measurement	PPARG	targetBased	0.446100866506194	6	196177	811
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	total blood protein measurement	PPARG	targetBased	0.446100866506194	6	196176	670
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	total blood protein measurement	PPARG	targetBased	0.446100866506194	6	196177	519
qHTS assay for re-activators of p53 using a Luc reporter	mean corpuscular hemoglobin concentration	TP53	pathwayBased	0.22762524462506	5	321427	201
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Nonpermissive Temperature	mean corpuscular hemoglobin concentration	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.22762524462506	5	54509	528
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Permissive Temperature	mean corpuscular hemoglobin concentration	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.22762524462506	5	54513	338
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature	mean corpuscular hemoglobin concentration	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.22762524462506	5	125394	1890
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Permissive Temperature	mean corpuscular hemoglobin concentration	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.22762524462506	5	124022	1156
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of myeloid cell leukemia sequence 1 (MCL1) interactions with BIM-BH3 peptide.	mean corpuscular hemoglobin concentration	MCL1	targetBased	0.163623112197893	5	314998	2139
uHTS of Mcl-1/Bid interaction inhibitors	mean corpuscular hemoglobin concentration	MCL1	targetBased	0.163623112197893	5	218602	2129
uHTS of Mcl-1/Noxa interaction inhibitors	mean corpuscular hemoglobin concentration	MCL1	targetBased	0.163623112197893	5	217330	3334
uHTS Colorimetric assay for identification of inhibitors of Scp-1	mean corpuscular hemoglobin concentration	CTDSP1_inhibitors	targetBased	0.233755114576688	8	340696	2986
Inhibitors of CDC25B-CDK2/CyclinA interaction	mean corpuscular hemoglobin concentration	Inhibitors of CDC25B-CDK2/CyclinA interaction	targetBased	0.405159684046205	6	93798	679
qHTS Assay for Identifying a Potential Treatment of Ataxia-Telangiectasia	mean corpuscular hemoglobin concentration	ATM_modulators	targetBased	0.116168008402556	5	322361	619
Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2	mean corpuscular hemoglobin concentration	THRB	targetBased	0.524565260505853	15	276265	806
Luminescence Cell-Based Primary HTS to Identify Inhibitors of A1 Apoptosis.	mean corpuscular hemoglobin concentration	BCL2L11_inhibitors	targetBased	0.510821888035741	32	325630	216
uHTS Fluorescent assay for identification of inhibitors of hexokinase domain containing I (HKDC1)	mean corpuscular hemoglobin concentration	HKDC1	targetBased	0.489741531716357	17	340696	540
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb via a fluorescence resonance energy transfer (FRET) assay.	mean corpuscular hemoglobin concentration	RUNX1	targetBased	0.27470784506411	6	215667	993
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay.	mean corpuscular hemoglobin concentration	RUNX1	targetBased	0.27470784506411	6	218234	1620
Inhibitors of USP1/UAF1: Primary Screen	mean corpuscular hemoglobin concentration	USP1	targetBased	0.289912631690962	5	389569	904
uHTS Luminescent assay for identification of inhibitors of NALP3 in yeast	mean corpuscular hemoglobin concentration	NLRP3	targetBased	0.402734360887653	6	330392	1295
Primary biochemical high-throughput screening assay to measure P97 ATPase inhibition	mean corpuscular hemoglobin concentration	VCP	targetBased	0.28622713577141	5	217959	923
Primary cell-based high throughput screening assay to measure STAT3 activation	mean corpuscular hemoglobin concentration	STAT3	pathwayBased	0.343492797529548	5	194666	1772
Primary cell-based high throughput screening assay to measure STAT3 inhibition	mean corpuscular hemoglobin concentration	STAT3	pathwayBased	0.343492797529548	5	194666	1722
qHTS Assay for Activators of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease	mean corpuscular hemoglobin concentration	GAA	targetBased	0.327986251796331	14	199169	715
qHTS Assay for Inhibitors and Activators of Human alpha-Glucosidase Cleavage of Glycogen	mean corpuscular hemoglobin concentration	GAA_inhibitors	targetBased	0.327986251796331	14	302297	1165
qHTS Assay for NPC1 Promoter Activators	hematological measurement	NPC1	pathwayBased	0.361933427258779	44	320682	7575
High Content Assay for Compounds that inhibit the Assembly of the Perinucleolar Compartment	hemoglobin measurement	PTBP1	targetBased	0.418305979038838	20	139718	4338
uHTS identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay	mean corpuscular hemoglobin concentration	UBE2N	targetBased	0.412857633425904	12	330393	1538
AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of microphthalmia-associated transcription factor (MITF)	mean corpuscular hemoglobin concentration	MITF inhibitors	targetBased	0.368740643042664	5	642362	5830
MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Inhibitor_SinglePoint_HTS_Activity	mean corpuscular hemoglobin concentration	MITF	targetBased	0.368740643042664	5	331360	2760
Primary qHTS for Inhibitors of ATXN expression	mean corpuscular hemoglobin concentration	ATXN2_repressors	targetBased	0.306927892008109	9	358434	2554
Primary HTS Assay for S1P3 Antagonists	mean corpuscular hemoglobin concentration	S1PR3	targetBased	0.313145055525362	9	169141	462
Fluorescence-based primary biochemical high throughput screening assay to identify inhibitors of Protein Phosphatase 5 (PP5).	hemoglobin measurement	PPP5C	targetBased	0.380474009505075	7	314999	564
Primary cell-based high-throughput screening assay for identification of compounds that inhibit KCNQ1 potassium channels	hemoglobin measurement	KCNQ1	targetBased	0.175993535276479	8	305610	3878
Primary cell-based high-throughput screening assay for identification of compounds that potentiate/activate KCNQ1 potassium channels	hemoglobin measurement	KCNQ1	targetBased	0.175993535276479	8	305610	1082
Primary Cell-based High Throughput Screening assay for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA)	hemoglobin measurement	RORA	pathwayBased	0.405256297337626	8	64908	979
Primary Cell-based High Throughput Screening assay for inhibitors of the Retinoic Acid Receptor-related orphan receptor A (RORA)	hemoglobin measurement	RORA	pathwayBased	0.405256297337626	8	64908	278
Luminescence Cell-Based Primary HTS to Identify Inhibitors of A1 Apoptosis.	total blood protein measurement	BCL2L11_inhibitors	targetBased	0.178170420271841	11	325630	216
qHTS for Agonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1): primary screen	hemoglobin measurement	RAPGEF3	targetBased	0.105177154752737	4	364614	268
qHTS for Antagonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1): primary screen	hemoglobin measurement	RAPGEF3	targetBased	0.105177154752737	4	364614	517
uHTS identification of small molecule inhibitors of the catalytic domain of the SUMO protease, SENP1 in a FRET assay	hemoglobin measurement	SENP1	targetBased	0.185426102807275	18	363840	774
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	hemoglobin measurement	JAK2	targetBased	0.226354422402905	30	217959	2390
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of the interaction of the Ras and Rab interactor 1 protein (Rin1) and the c-abl oncogene 1, non-receptor tyrosine kinase (Abl)	hemoglobin measurement	ABL1_interaction	targetBased	0.150704791317691	5	359207	1432
qHTS Assay for Inhibitors of the ERK Signaling Pathway using a Homogeneous Screening Assay	hemoglobin measurement	MAPK1	pathwayBased	0.171573470794509	4	70898	707
qHTS Assay for Inhibitors of the ERK Signaling Pathway using a Homogeneous Screening Assay; Stimulation with EGF	hemoglobin measurement	MAPK1	pathwayBased	0.171573470794509	4	131324	544
Identification of CBX7 inhibitors - Primary Alpha Screen	hemoglobin measurement	Chromobox protein homolog 7 inhibitors	targetBased	0.377998022841213	7	64999	724
Identification of Molecular Probes that Activate MRP-1	hemoglobin measurement	ABCC1_activators	targetBased	0.204002755840247	12	138717	842
EZH2/PRC2 methyltransferase inhibitors Measured in Biochemical System Using Plate Reader - 2125-01_Inhibitor_SinglePoint_HTS_Activity	hemoglobin measurement	EZH2_inhibitors	targetBased	0.149729037878502	11	57013	201
Cell-based coincidence reporter assay to measure PMP22 gene transcription in S16 Pmp22-F2sN cells - Primary screen	hemoglobin measurement	PMP22	targetBased	0.251292782798315	5	42576	834
High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Primary Screen	hemoglobin measurement	NFKB1	pathwayBased	0.153036405124449	23	193265	3100
uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay	hemoglobin measurement	NFKB1	pathwayBased	0.153036405124449	23	359244	3094
qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode)	hemoglobin measurement	GLP1R	targetBased	0.184927182190094	10	405130	6428
qHTS of GLP-1 Receptor Agonists	hemoglobin measurement	GLP1R agonists	targetBased	0.184927182190094	10	373462	23
qHTS of GLP-1 Receptor Inverse Agonists: (PAM Mode) (Taking the negative queue for PAMs)	hemoglobin measurement	GLP1R PAMs	targetBased	0.184927182190094	10	405130	6428
uHTS identification of HIF-2a Inhibitors in a luminesence assay	hemoglobin measurement	HIF-2a_inhibitors	targetBased	0.528898317686333	73	363840	2624
Nrf2 qHTS screen for inhibitors	hemoglobin measurement	nrf2Inhibitors	targetBased	0.106003059757178	20	360873	7438
qHTS of Nrf2 Activators	hemoglobin measurement	Nrf2 activators	pathwayBased	0.106003059757178	20	403871	1243
Luminescence-based cell-based primary high throughput screening assay to identify inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2)	hemoglobin measurement	NR5A2	targetBased	0.496924154016705	8	363803	458
uHTS for the identification of compounds that potentiate TRAIL-induced apoptosis of cancer cells	hemoglobin measurement	TNFSF10	targetBased	0.368648470983396	6	217035	883
Fluorescence-based biochemical high throughput primary assay to identify inhibitors of phospholipase C isozymes (PLC-gamma1).	hemoglobin measurement	PLCG1	targetBased	0.471152545660037	11	369953	3123
HTS for PAX8 inhibitors using PAX8 luciferase reporter gene assay in RMG-I cells Measured in Cell-Based System Using Plate Reader - 7054-01_Inhibitor_SinglePoint_HTS_Activity	hemoglobin measurement	PAX8	targetBased	0.320425130987108	36	353950	4145
Primary cell-based high-throughput screening assay for identification of compounds that inhibit KCNQ1 potassium channels	HbA1c measurement	KCNQ1	targetBased	0.4826970259039	14	305610	3878
Primary cell-based high-throughput screening assay for identification of compounds that potentiate/activate KCNQ1 potassium channels	HbA1c measurement	KCNQ1	targetBased	0.4826970259039	14	305610	1082
Identification of Molecular Probes that Activate MRP-1	HbA1c measurement	ABCC1_activators	targetBased	0.469785407126004	6	138717	842
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	HbA1c measurement	PPARG	targetBased	0.408599309051904	6	99314	335
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	HbA1c measurement	PPARG	targetBased	0.408599309051904	6	196176	782
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	HbA1c measurement	PPARG	targetBased	0.408599309051904	6	99314	390
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	HbA1c measurement	PPARG	targetBased	0.408599309051904	6	196177	811
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	HbA1c measurement	PPARG	targetBased	0.408599309051904	6	196176	670
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	HbA1c measurement	PPARG	targetBased	0.408599309051904	6	196177	519
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	hemoglobin measurement	PPARG	targetBased	0.5118851697251	28	99314	335
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	hemoglobin measurement	PPARG	targetBased	0.5118851697251	28	196176	782
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	hemoglobin measurement	PPARG	targetBased	0.5118851697251	28	99314	390
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	hemoglobin measurement	PPARG	targetBased	0.5118851697251	28	196177	811
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	hemoglobin measurement	PPARG	targetBased	0.5118851697251	28	196176	670
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	hemoglobin measurement	PPARG	targetBased	0.5118851697251	28	196177	519
E3 Ligase HTS_1536	hemoglobin measurement	MDM2	targetBased	0.127060548414315	5	207811	220
HTS for Estrogen Receptor-beta Coactivator Binding inhibitors	hemoglobin measurement	ESR2_inhibitors	targetBased	0.55712159008365	14	86095	1114
qHTS assay for re-activators of p53 using a Luc reporter	hemoglobin measurement	TP53	pathwayBased	0.127975408110069	66	321427	201
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Nonpermissive Temperature	hemoglobin measurement	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.127975408110069	66	54509	528
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Permissive Temperature	hemoglobin measurement	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.127975408110069	66	54513	338
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature	hemoglobin measurement	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.127975408110069	66	125394	1890
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Permissive Temperature	hemoglobin measurement	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.127975408110069	66	124022	1156
Primary screen for compounds that inhibit Alzheimer's amyloid precursor protein (APP) translation	hemoglobin measurement	APP_inhibitors	pathwayBased	0.161069198956558	4	193714	1590
Primary screen for compounds that activate Alzheimer's amyloid precursor	hemoglobin measurement	APP_inhibitors	pathwayBased	0.161069198956558	4	193400	1987
qHTS for compounds that reverse cellular toxicity of Amyloid beta (A-beta) peptide in yeast: Primary Screen	hemoglobin measurement	APP_inhibitors	targetBased	0.161069198956558	4	404343	257
Inhibitors of CDC25B-CDK2/CyclinA interaction	hemoglobin measurement	Inhibitors of CDC25B-CDK2/CyclinA interaction	targetBased	0.151841566165851	5	93798	679
Fluorescence-based biochemical high throughput primary assay to identify inhibitors of phospholipase C isozymes (PLC-beta3).	hemoglobin measurement	PLCB3	targetBased	0.13007335892678	5	369953	662
Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2	hemoglobin measurement	THRB	targetBased	0.404018660224815	11	276265	806
Luminescence Cell-Based Primary HTS to Identify Inhibitors of A1 Apoptosis.	hemoglobin measurement	BCL2L11_inhibitors	targetBased	0.333221104587618	27	325630	216
uHTS Fluorescent assay for identification of inhibitors of hexokinase domain containing I (HKDC1)	hemoglobin measurement	HKDC1	targetBased	0.489770536132633	42	340696	540
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb via a fluorescence resonance energy transfer (FRET) assay.	hemoglobin measurement	RUNX1	targetBased	0.307128777588598	17	215667	993
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay.	hemoglobin measurement	RUNX1	targetBased	0.307128777588598	17	218234	1620
uHTS Luminescent assay for identification of inhibitors of NALP3 in yeast	hemoglobin measurement	NLRP3	targetBased	0.310604840439728	9	330392	1295
CYP2C19 Assay	hemoglobin measurement	CYP2C19_inhibitors	targetBased	0.101471026445566	4	95857	20295
HTS of Smad transcription factor inhibitors	hemoglobin measurement	SMAD3	targetBased	0.33073460722489	8	88033	251
uHTS Fluorescent assay for identification of inhibitors of hexokinase domain containing I (HKDC1)	HbA1c measurement	HKDC1	targetBased	0.427267072675693	32	340696	540
Primary qHTS for Inhibitors of ATXN expression	HbA1c measurement	ATXN2_repressors	targetBased	0.134066268487385	5	358434	2554
Primary HTS Assay for S1P3 Antagonists	HbA1c measurement	S1PR3	targetBased	0.461961520160537	9	169141	462
Primary screen for compounds that activate Insulin promoter activity in TRM-6 cells	HbA1c measurement	INS	targetBased	0.435333500581763	5	128695	1039
Primary screen for compounds that inhibit Insulin promoter activity in TRM-6 cells	HbA1c measurement	INS	targetBased	0.435333500581763	5	127961	1153
Primary cell-based high throughput screening assay to measure STAT3 activation	hemoglobin measurement	STAT3	pathwayBased	0.126308022410103	10	194666	1772
Primary cell-based high throughput screening assay to measure STAT3 inhibition	hemoglobin measurement	STAT3	pathwayBased	0.126308022410103	10	194666	1722
Primary cell-based screen for identification of compounds that inhibit the two-pore domain potassium channel KCNK3	hemoglobin measurement	KCNK3	targetBased	0.18826029724473	4	339674	2841
Inhibition of the MLL-AF4-AF9 Interaction in Pediatric Leukemia Measured in Biochemical System Using Plate Reader - 2160-01_Inhibitor_SinglePoint_HTS_Activity	hemoglobin measurement	MLLT3	targetBased	0.449948874612741	4	344459	1627
qHTS screen for small molecules that induce genotoxicity in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1	hemoglobin measurement	ATAD5_inhibitors	targetBased	0.217930494015768	6	330109	4174
qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1	hemoglobin measurement	ATAD5_inhibitors	targetBased	0.217930494015768	6	330107	7652
HTS identification of compounds activating phosphomannose isomerase (PMI) via a fluorescence intensity assay using a near- saturating concentration of mannose 6-phosphat	hemoglobin measurement	MPI	targetBased	0.130469065080739	5	194152	656
HTS identification of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay using a high concentration of mannose 6-phosphate	hemoglobin measurement	MPI	targetBased	0.130469065080739	5	194152	1288
HTS identification of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay.	hemoglobin measurement	MPI	targetBased	0.130469065080739	5	194152	814
qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding	hemoglobin measurement	MAPT	pathwayBased	0.259465059910697	19	267412	5703
qHTS Assay for Tau Filament Binding	hemoglobin measurement	MAPT	targetBased	0.259465059910697	19	69668	1391
qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization	hemoglobin measurement	MAPT	pathwayBased	0.259465059910697	19	271402	1048
AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of microphthalmia-associated transcription factor (MITF)	hemoglobin measurement	MITF inhibitors	targetBased	0.570577910064087	16	642362	5830
MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Inhibitor_SinglePoint_HTS_Activity	hemoglobin measurement	MITF	targetBased	0.570577910064087	16	331360	2760
Primary qHTS for Inhibitors of ATXN expression	hemoglobin measurement	ATXN2_repressors	targetBased	0.41635995475247	32	358434	2554
Primary screen for compounds that activate Insulin promoter activity in TRM-6 cells	hemoglobin measurement	INS	targetBased	0.171620107292571	8	128695	1039
Primary screen for compounds that inhibit Insulin promoter activity in TRM-6 cells	hemoglobin measurement	INS	targetBased	0.171620107292571	8	127961	1153
Primary Cell-based High Throughput Screening assay for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA)	bilirubin measurement	RORA	pathwayBased	0.283924615068288	5	64908	979
Primary Cell-based High Throughput Screening assay for inhibitors of the Retinoic Acid Receptor-related orphan receptor A (RORA)	bilirubin measurement	RORA	pathwayBased	0.283924615068288	5	64908	278
HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Inhibitor_SinglePoint_HTS_Activity	bilirubin measurement	SCARB1	targetBased	0.473205943174413	5	319204	3065
HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Activator_SinglePoint_HTS_Activity	bilirubin measurement	SCARB1	targetBased	0.473205943174413	5	316970	306
Luminescence-based primary cell-based high throughput screening assay to identify activators of the Aryl Hydrocarbon Receptor (AHR)	bilirubin measurement	AHR_activators	targetBased	0.355118244817678	6	324747	7988
Luminescence-based cell-based high throughput primary screening assay to identify agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3)	hemoglobin measurement	NR2E3	targetBased	0.262752556078429	10	362026	1281
TR-FRET-based primary biochemical high throughput screening assay to identify agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3).	hemoglobin measurement	NR2E3	targetBased	0.262752556078429	10	314998	380
High Content Assay for Compounds that inhibit the Assembly of the Perinucleolar Compartment	serum gamma-glutamyl transferase measurement	PTBP1	targetBased	0.391746296847476	8	139718	4338
ARNT-TAC3: AlphaScreen HTS to detect disruption of ARNT/TAC3 interactions Measured in Biochemical System Using Plate Reader - 2158-01_Inhibitor_SinglePoint_HTS_Activity	serum gamma-glutamyl transferase measurement	TACC3	targetBased	0.30184297729586	5	391179	2589
Primary Cell-based High Throughput Screening assay for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA)	serum gamma-glutamyl transferase measurement	RORA	pathwayBased	0.413653881191419	20	64908	979
Primary Cell-based High Throughput Screening assay for inhibitors of the Retinoic Acid Receptor-related orphan receptor A (RORA)	serum gamma-glutamyl transferase measurement	RORA	pathwayBased	0.413653881191419	20	64908	278
qHTS for Inhibitors of TGF-b	serum gamma-glutamyl transferase measurement	TGFB1	pathwayBased	0.300503655770074	6	403345	4970
Luminescence-based cell-based primary high throughput screening assay to identify inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2)	serum gamma-glutamyl transferase measurement	NR5A2	targetBased	0.24552458138369	9	363803	458
uHTS identification of Caspase-8 TRAIL sensitizers in a luminesence assay	serum gamma-glutamyl transferase measurement	TNFRSF10B	targetBased	0.351594278959815	14	363840	3764
uHTS for the identification of compounds that potentiate TRAIL-induced apoptosis of cancer cells	serum gamma-glutamyl transferase measurement	TNFSF10	targetBased	0.429554515347021	6	217035	883
Fluorescence-based biochemical high throughput primary assay to identify inhibitors of phospholipase C isozymes (PLC-gamma1).	serum gamma-glutamyl transferase measurement	PLCG1	targetBased	0.230365901791831	6	369953	3123
uHTS identification of DNMT1 inhibitors in a Fluorescent Molecular Beacon assay	serum gamma-glutamyl transferase measurement	DNMT1	targetBased	0.259930107780037	5	359244	2975
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	serum gamma-glutamyl transferase measurement	PPARG	targetBased	0.475911745091515	9	99314	335
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	serum gamma-glutamyl transferase measurement	PPARG	targetBased	0.475911745091515	9	196176	782
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	serum gamma-glutamyl transferase measurement	PPARG	targetBased	0.475911745091515	9	99314	390
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	serum gamma-glutamyl transferase measurement	PPARG	targetBased	0.475911745091515	9	196177	811
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	serum gamma-glutamyl transferase measurement	PPARG	targetBased	0.475911745091515	9	196176	670
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	serum gamma-glutamyl transferase measurement	PPARG	targetBased	0.475911745091515	9	196177	519
Fluorescence-based biochemical high throughput primary assay to identify inhibitors of phospholipase C isozymes (PLC-gamma1).	bilirubin measurement	PLCG1	targetBased	0.312152311604298	8	369953	3123
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	bilirubin measurement	PPARG	targetBased	0.346024715595505	5	99314	335
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	bilirubin measurement	PPARG	targetBased	0.346024715595505	5	196176	782
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	bilirubin measurement	PPARG	targetBased	0.346024715595505	5	99314	390
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	bilirubin measurement	PPARG	targetBased	0.346024715595505	5	196177	811
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	bilirubin measurement	PPARG	targetBased	0.346024715595505	5	196176	670
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	bilirubin measurement	PPARG	targetBased	0.346024715595505	5	196177	519
uHTS Luminescent assay for identification of inhibitors of NALP3 in yeast	bilirubin measurement	NLRP3	targetBased	0.430063805756983	5	330392	1295
uHTS Luminescent assay for identification of inhibitors of human intestinal alkaline phosphatase	bilirubin measurement	ALPI_inhibitors	targetBased	0.148874131971429	5	330392	393
uHTS Luminescent assay for identification of inhibitors of mouse intestinal alkaline phosphatase	bilirubin measurement	ALPI_inhibitors	targetBased	0.148874131971429	5	331670	664
Luminescent assay for identification of activators of bovine intestinal alkaline phosphatase	bilirubin measurement	ALPI_activators	targetBased	0.148874131971429	5	195570	326
uHTS Luminescent assay for identification of activators of human intestinal alkaline phosphatase	bilirubin measurement	ALPI_activators	targetBased	0.148874131971429	5	330392	537
uHTS Luminescent assay for identification of activators of mouse intestinal alkaline phosphatase	bilirubin measurement	ALPI_activators	targetBased	0.148874131971429	5	331670	785
Primary qHTS for Inhibitors of ATXN expression	bilirubin measurement	ATXN2_repressors	targetBased	0.331584587391504	8	358434	2554
Primary HTS Assay for S1P3 Antagonists	bilirubin measurement	S1PR3	targetBased	0.390644697952536	8	169141	462
qHTS assay to identify small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway	serum gamma-glutamyl transferase measurement	RORCgammaPathwayInhibitors	pathwayBased	0.630287012112818	11	7671	874
VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity	serum gamma-glutamyl transferase measurement	RORC	targetBased	0.630287012112818	11	304060	10600
qHTS for inhibitors of ROR gamma transcriptional activity	serum gamma-glutamyl transferase measurement	RORCgammaPathwayInhibitors	pathwayBased	0.630287012112818	11	305439	16717
Luminescence Cell-Based Primary HTS to Identify Inhibitors of A1 Apoptosis.	serum gamma-glutamyl transferase measurement	BCL2L11_inhibitors	targetBased	0.366237826653842	5	325630	216
Primary HTS and Confirmation Assays for S1P1 Agonists and Agonism Potentiators	serum gamma-glutamyl transferase measurement	S1PR1	targetBased	0.415009151934445	5	55710	315
Luminescence-based cell-based primary high throughput screening assay to identify inhibitors of COUP-TFII (NR2F2)	serum gamma-glutamyl transferase measurement	NR2F2	targetBased	0.253500734148187	5	369953	2602
Primary Cell-Based High-Throughput Screening to Identify Agonists of the Sphingosine 1-phosphate receptor 2 (S1P2)	serum gamma-glutamyl transferase measurement	S1PR2	targetBased	0.286573600668818	5	96879	447
Primary Cell-Based High-Throughput Screening to Identify Antagonists of the Sphingosine 1-phosphate receptor 2 (S1P2)	serum gamma-glutamyl transferase measurement	S1PR2	targetBased	0.286573600668818	5	96879	207
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	mean corpuscular hemoglobin concentration	JAK2	targetBased	0.410581037684709	8	217959	2390
FRET-based HTS for detection of RAD52 Inhibitors Measured in Biochemical System Using Plate Reader - 7018-01_Inhibitor_SinglePoint_HTS_Activity_Set2	mean corpuscular volume	RAD52	targetBased	0.298178741539508	6	352074	1608
High Content Assay for Compounds that inhibit the Assembly of the Perinucleolar Compartment	mean corpuscular volume	PTBP1	targetBased	0.197170753886727	5	139718	4338
ARNT-TAC3: AlphaScreen HTS to detect disruption of ARNT/TAC3 interactions Measured in Biochemical System Using Plate Reader - 2158-01_Inhibitor_SinglePoint_HTS_Activity	mean corpuscular volume	TACC3	targetBased	0.200355827615776	6	391179	2589
HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Inhibitor_SinglePoint_HTS_Activity	mean corpuscular volume	SCARB1	targetBased	0.513853241245553	11	319204	3065
HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Activator_SinglePoint_HTS_Activity	mean corpuscular volume	SCARB1	targetBased	0.513853241245553	11	316970	306
HTS to identify compounds that promote myeloid differentiation with MLPCN compound set	mean corpuscular volume	HOXA9	pathwayBased	0.429367104434106	8	358556	3721
qHTS for Agonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1): primary screen	mean corpuscular volume	RAPGEF3	targetBased	0.227967350807441	8	364614	268
qHTS for Antagonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1): primary screen	mean corpuscular volume	RAPGEF3	targetBased	0.227967350807441	8	364614	517
uHTS identification of small molecule inhibitors of the catalytic domain of the SUMO protease, SENP1 in a FRET assay	mean corpuscular volume	SENP1	targetBased	0.218827761281645	11	363840	774
HTS Assay for Peg3 Promoter Inhibitors	mean corpuscular volume	PPP1R15A	targetBased	0.385102605585072	5	359244	6145
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	mean corpuscular volume	JAK2	targetBased	0.495086523069834	35	217959	2390
qHTS for Inhibitors of Polymerase Iota	mean corpuscular volume	POLI	targetBased	0.165678327491817	14	386063	3989
Primary cell-based high throughput screening assay to identify inhibitors of kruppel-like factor 5 (KLF5)	mean corpuscular volume	KLF5	targetBased	0.184503479565994	5	290726	671
Identification of Molecular Probes that Activate MRP-1	mean corpuscular volume	ABCC1_activators	targetBased	0.507486032664877	11	138717	842
uHTS luminescence assay for the identification of compounds that inhibit NOD1	mean corpuscular volume	NOD1	targetBased	0.491493659851193	11	289422	2997
EZH2/PRC2 methyltransferase inhibitors Measured in Biochemical System Using Plate Reader - 2125-01_Inhibitor_SinglePoint_HTS_Activity	mean corpuscular volume	EZH2_inhibitors	targetBased	0.355421073770493	8	57013	201
Fluorescence Biochemical Primary HTS to Identify Inhibitors of GASC-1 Activity	mean corpuscular volume	KDM4C	targetBased	0.448225343771325	14	326066	228
qHTS Assay for Inhibitors of GCN5L2	mean corpuscular volume	KAT2A	targetBased	0.110687201777752	11	381571	792
High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Primary Screen	mean corpuscular volume	NFKB1	pathwayBased	0.514100334861674	12	193265	3100
uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay	mean corpuscular volume	NFKB1	pathwayBased	0.514100334861674	12	359244	3094
HTS for Identification of VLA-4 Allosteric Modulators from MLPCN library	mean corpuscular volume	ITGA4	targetBased	0.494868534529795	11	326888	645
Small-molecule inhibitors of ST2 (IL1RL1)	mean corpuscular volume	IL1RL1	targetBased	0.17563408501836	8	75924	1804
Flow Cytometric HTS Screen for inhibitors of the ABC transporter ABCB6 for MLPCN Compound Set	mean corpuscular volume	ABCB6_inhibitors	targetBased	0.162599022155718	11	362098	692
uHTS identification of Caspase-8 TRAIL sensitizers in a luminesence assay	mean corpuscular volume	TNFRSF10B	targetBased	0.425003211832304	8	363840	3764
uHTS for the identification of compounds that potentiate TRAIL-induced apoptosis of cancer cells	mean corpuscular volume	TNFSF10	targetBased	0.410249718566688	6	217035	883
Primary Cell-Based Assay to Identify Agonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	mean corpuscular volume	S1PR4	targetBased	0.328789668811452	6	217959	771
Primary Cell-Based Assay to Identify Antagonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	mean corpuscular volume	S1PR4	targetBased	0.328789668811452	6	217959	569
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	mean corpuscular volume	PPARG	targetBased	0.397214953460093	15	99314	335
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	mean corpuscular volume	PPARG	targetBased	0.397214953460093	15	196176	782
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	mean corpuscular volume	PPARG	targetBased	0.397214953460093	15	99314	390
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	mean corpuscular volume	PPARG	targetBased	0.397214953460093	15	196177	811
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	mean corpuscular volume	PPARG	targetBased	0.397214953460093	15	196176	670
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	mean corpuscular volume	PPARG	targetBased	0.397214953460093	15	196177	519
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of 5-meCpG-binding domain protein 2 (MBD2)-DBD binding to methylated oligonucleotide	mean corpuscular volume	MBD2	targetBased	0.411762934088018	12	369953	1149
Primary biochemical high-throughput screening assay for inhibitors of Rho kinase 2 (Rhok2)	mean corpuscular volume	ROCK2	targetBased	0.43921499853059	9	59788	212
E3 Ligase HTS_1536	mean corpuscular volume	MDM2	targetBased	0.452431188155701	9	207811	220
uHTS Luminescent assay for identification of inhibitors of Sentrin-specific protease 7 (SENP7)	mean corpuscular volume	SENP7	targetBased	0.396878522095073	11	331670	4902
Primary cell-based high-throughput screening assay for identification of compounds that inhibit KCNQ1 potassium channels	mean platelet volume	KCNQ1	targetBased	0.369442776593038	5	305610	3878
Primary cell-based high-throughput screening assay for identification of compounds that potentiate/activate KCNQ1 potassium channels	mean platelet volume	KCNQ1	targetBased	0.369442776593038	5	305610	1082
uHTS Luminescent assay for identification of inhibitors of NALP3 in yeast	fibrinogen measurement	NLRP3	targetBased	0.42762567249088	8	330392	1295
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	fibrinogen measurement	FGB_inhibitors	targetBased	0.558074033786004	29	369953	760
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	fibrinogen measurement	FGB_inhibitors	targetBased	0.558074033786004	29	369953	498
qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS	mean platelet volume	GNAS	targetBased	0.143298713341642	5	334825	423
qHTS for Antagonists of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS	mean platelet volume	GNAS	targetBased	0.143298713341642	5	337446	1356
qHTS for Agonists of the Human Mucolipin Transient Receptor Potential 1 (TRPML1)	mean platelet volume	MCOLN1	targetBased	0.27953084574565	6	400814	482
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	mean platelet volume	JAK2	targetBased	0.43115176434106	11	217959	2390
qHTS of IL-2 Activators	mean platelet volume	IL2	targetBased	0.104679268934682	11	364617	238
Primary cell-based high throughput screening assay to measure STAT1 activation	mean platelet volume	STAT1 activation	pathwayBased	0.377958403672447	14	195980	5134
Primary cell-based high throughput screening assay to measure STAT1 inhibition	mean platelet volume	STAT1	targetBased	0.377958403672447	14	195980	695
qHTS for Inhibitors of Glutaminase (GLS)	mean platelet volume	GLS	targetBased	0.508735256331516	15	405291	844
qHTS Assay for NPC1 Promoter Activators	mean corpuscular volume	NPC1	pathwayBased	0.482642394660918	20	320682	7575
qHTS assay for re-activators of p53 using a Luc reporter	mean corpuscular volume	TP53	pathwayBased	0.268249432318912	11	321427	201
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Nonpermissive Temperature	mean corpuscular volume	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.268249432318912	11	54509	528
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Permissive Temperature	mean corpuscular volume	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.268249432318912	11	54513	338
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature	mean corpuscular volume	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.268249432318912	11	125394	1890
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Permissive Temperature	mean corpuscular volume	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.268249432318912	11	124022	1156
Inhibitors of CDC25B-CDK2/CyclinA interaction	mean corpuscular volume	Inhibitors of CDC25B-CDK2/CyclinA interaction	targetBased	0.434302998852747	21	93798	679
qHTS Assay for Identifying a Potential Treatment of Ataxia-Telangiectasia	mean corpuscular volume	ATM_modulators	targetBased	0.462347187212411	21	322361	619
Fluorescence-based biochemical high throughput primary assay to identify inhibitors of phospholipase C isozymes (PLC-beta3).	mean corpuscular volume	PLCB3	targetBased	0.381894597957024	9	369953	662
Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2	mean corpuscular volume	THRB	targetBased	0.537191446714195	32	276265	806
High throughput discovery of novel modulators of ROMK K+ channel activity: Primary Screen	mean corpuscular volume	KCNJ1	targetBased	0.188750000587688	5	125268	2463
Luminescence Cell-Based Primary HTS to Identify Inhibitors of A1 Apoptosis.	mean corpuscular volume	BCL2L11_inhibitors	targetBased	0.533529352493559	83	325630	216
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors of ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 (ASAP1)	mean corpuscular volume	ASAP1_inhibitors	targetBased	0.349885589793323	5	362577	680
uHTS Fluorescent assay for identification of inhibitors of hexokinase domain containing I (HKDC1)	mean corpuscular volume	HKDC1	targetBased	0.522587039922814	26	340696	540
Dyrk1 A HTS Measured in Biochemical System Using Plate Reader - 2124-01_Inhibitor_SinglePoint_HTS_Activity	mean corpuscular volume	DYRK1A_inhibitors	targetBased	0.316540561391068	6	310014	1321
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb via a fluorescence resonance energy transfer (FRET) assay.	mean corpuscular volume	RUNX1	targetBased	0.271395347839884	14	215667	993
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay.	mean corpuscular volume	RUNX1	targetBased	0.271395347839884	14	218234	1620
Inhibitors of USP1/UAF1: Primary Screen	mean corpuscular volume	USP1	targetBased	0.362656666345068	12	389569	904
Primary biochemical high-throughput screening assay to measure P97 ATPase inhibition	mean corpuscular volume	VCP	targetBased	0.373099559915259	9	217959	923
Fluorescence polarization assay for PLK1 inhibitors	mean corpuscular volume	PLK1	targetBased	0.483550057715321	6	97099	518
qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen	mean corpuscular volume	PLK1	targetBased	0.483550057715321	6	364065	10181
Primary cell-based high throughput screening assay to measure STAT3 activation	mean corpuscular volume	STAT3	pathwayBased	0.400456367147502	11	194666	1772
Primary cell-based high throughput screening assay to measure STAT3 inhibition	mean corpuscular volume	STAT3	pathwayBased	0.400456367147502	11	194666	1722
Primary biochemical high-throughput screening assay for inhibitors of Focal Adhesion Kinase (FAK)	mean corpuscular volume	PTK2	targetBased	0.374507874913564	6	96879	811
Primary Cell-Based Assay to Identify Agonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	mean platelet volume	S1PR4	targetBased	0.399460854113686	6	217959	771
Primary Cell-Based Assay to Identify Antagonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	mean platelet volume	S1PR4	targetBased	0.399460854113686	6	217959	569
qHTS assay for re-activators of p53 using a Luc reporter	mean platelet volume	TP53	pathwayBased	0.148747455788064	6	321427	201
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Nonpermissive Temperature	mean platelet volume	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.148747455788064	6	54509	528
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Permissive Temperature	mean platelet volume	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.148747455788064	6	54513	338
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature	mean platelet volume	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.148747455788064	6	125394	1890
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Permissive Temperature	mean platelet volume	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.148747455788064	6	124022	1156
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors of ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 (ASAP1)	mean platelet volume	ASAP1_inhibitors	targetBased	0.496928940198969	9	362577	680
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb via a fluorescence resonance energy transfer (FRET) assay.	mean platelet volume	RUNX1	targetBased	0.262548740339143	9	215667	993
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay.	mean platelet volume	RUNX1	targetBased	0.262548740339143	9	218234	1620
Inhibitors of USP1/UAF1: Primary Screen	mean platelet volume	USP1	targetBased	0.154085311659509	6	389569	904
MLPCN ERAP1 Measured in Biochemical System Using Plate Reader - 7016-01_Inhibitor_SinglePoint_HTS_Activity	mean platelet volume	ERAP1_inhibitors	targetBased	0.451494962964393	6	335777	499
Fluorescence-based primary biochemical high throughput screening assay to identify inhibitors of human diacylglycerol lipase, beta (DAGLB)	mean platelet volume	DAGLB_inhibitors	targetBased	0.47560972953071	9	343468	202
uHTS for 14-3-3/Bad interaction inhibitors	mean platelet volume	YWHAZ	targetBased	0.448249876493934	6	217332	1549
Primary biochemical high-throughput screening assay to measure P97 ATPase inhibition	mean platelet volume	VCP	targetBased	0.389451073578214	8	217959	923
Counterscreen for inhibitors of PP5: fluorescence-based biochemical high throughput primary assay to identify inhibitors of Protein Phosphatase 1 (PP1).	mean corpuscular volume	PPP1CA	targetBased	0.117174952891707	9	314999	2841
qHTS screen for small molecules that induce genotoxicity in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1	mean corpuscular volume	ATAD5_inhibitors	targetBased	0.380463043009637	9	330109	4174
qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1	mean corpuscular volume	ATAD5_inhibitors	targetBased	0.380463043009637	9	330107	7652
uHTS identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay	mean corpuscular volume	UBE2N	targetBased	0.222672911374569	14	330393	1538
qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding	mean corpuscular volume	MAPT	pathwayBased	0.145411756676911	20	267412	5703
qHTS Assay for Tau Filament Binding	mean corpuscular volume	MAPT	targetBased	0.145411756676911	20	69668	1391
qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization	mean corpuscular volume	MAPT	pathwayBased	0.145411756676911	20	271402	1048
qHTS Assay for the Inhibitors of L3MBTL1	mean platelet volume	L3MBTL1	targetBased	0.11209969596943	6	225309	1492
AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of microphthalmia-associated transcription factor (MITF)	mean corpuscular volume	MITF inhibitors	targetBased	0.452845081361217	5	642362	5830
MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Inhibitor_SinglePoint_HTS_Activity	mean corpuscular volume	MITF	targetBased	0.452845081361217	5	331360	2760
Alphascreen assay for small molecules abrogating mHTT-CaM Interaction	mean platelet volume	HTT	targetBased	0.486183906440617	18	189882	6790
Primary qHTS for Identification of Small Molecule Inhibitors of Huntingtin Promoter Activity	mean platelet volume	HTT	targetBased	0.486183906440617	18	48068	449
qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Aggregate Formation (GFP)	mean platelet volume	HTT	targetBased	0.486183906440617	18	220571	2380
qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Cytoprotection (ATP)	mean platelet volume	HTT	targetBased	0.486183906440617	18	223611	305
Primary qHTS for Inhibitors of ATXN expression	mean platelet volume	ATXN2_repressors	targetBased	0.282645943223549	6	358434	2554
Primary HTS Assay for S1P3 Antagonists	mean platelet volume	S1PR3	targetBased	0.275373304610341	5	169141	462
Acumen qHTS Assay for Inhibitors of the mTORC1 Signaling Pathway in MEF (Tsc2-/-, p53-/-) Cells: Sytravon	mean corpuscular volume	MTOR	pathwayBased	0.196271316364943	8	43989	342
Primary qHTS for Inhibitors of ATXN expression	mean corpuscular volume	ATXN2_repressors	targetBased	0.313817054003646	9	358434	2554
Luminescence Cell-Based Primary HTS to Identify Inhibitors of A1 Apoptosis.	HbA1c measurement	BCL2L11_inhibitors	targetBased	0.435268381242898	8	325630	216
Primary HTS Assay for S1P3 Antagonists	mean corpuscular volume	S1PR3	targetBased	0.452053764014656	17	169141	462
Factor XIa 1536 HTS	coagulation factor measurement	F11_modulation	targetBased	0.515638045408026	6	218707	302
Factor XIa 1536 HTS	factor XI measurement	F11_modulation	targetBased	0.542242301761855	5	218707	302
HTS for developing T Cell Immune Modulators	neutrophil count	ITGAL	targetBased	0.405452227124094	11	326271	221
qHTS Assay to Identify Small Molecule Activators of BRCA1 Expression	neutrophil count	BRCA1 activation	pathwayBased	0.106631057623902	5	376029	3978
HTS to identify compounds that promote myeloid differentiation with MLPCN compound set	neutrophil count	HOXA9	pathwayBased	0.147132112538932	6	358556	3721
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	neutrophil count	JAK2	targetBased	0.453129596983325	8	217959	2390
Identification of CBX7 inhibitors - Primary Alpha Screen	neutrophil count	Chromobox protein homolog 7 inhibitors	targetBased	0.423235542720295	9	64999	724
qHTS for Inhibitors of Polymerase Iota	neutrophil count	POLI	targetBased	0.216920142469568	14	386063	3989
uHTS HTRF assay for identification of inhibitors of SUMOylation	neutrophil count	UBE2I	targetBased	0.267611212469029	10	290915	1039
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype	neutrophil count	RAB2A	targetBased	0.40069543250009	6	194628	365
HTS for Identification of VLA-4 Allosteric Modulators from MLPCN library	neutrophil count	ITGA4	targetBased	0.517363544154237	15	326888	645
Flow Cytometric HTS Screen for inhibitors of the ABC transporter ABCB6 for MLPCN Compound Set	neutrophil count	ABCB6_inhibitors	targetBased	0.176763618476787	8	362098	692
qHTS Assay for Inhibitors of BAZ2B	neutrophil count	BAZ2B_modulators	targetBased	0.293217145506306	9	356826	15709
Primary Cell-Based Assay to Identify Agonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	neutrophil count	S1PR4	targetBased	0.670237943777037	29	217959	771
Primary Cell-Based Assay to Identify Antagonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	neutrophil count	S1PR4	targetBased	0.670237943777037	29	217959	569
uHTS identification of DNMT1 inhibitors in a Fluorescent Molecular Beacon assay	neutrophil count	DNMT1	targetBased	0.234038439382085	12	359244	2975
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	neutrophil count	PPARG	targetBased	0.350234119924731	7	99314	335
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	neutrophil count	PPARG	targetBased	0.350234119924731	7	196176	782
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	neutrophil count	PPARG	targetBased	0.350234119924731	7	99314	390
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	neutrophil count	PPARG	targetBased	0.350234119924731	7	196177	811
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	neutrophil count	PPARG	targetBased	0.350234119924731	7	196176	670
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	neutrophil count	PPARG	targetBased	0.350234119924731	7	196177	519
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of 5-meCpG-binding domain protein 2 (MBD2)-DBD binding to methylated oligonucleotide	neutrophil count	MBD2	targetBased	0.373210454966113	14	369953	1149
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac activated mutant	neutrophil count	RAC1	targetBased	0.188104446729012	5	194629	219
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac wildtype	neutrophil count	RAC1	targetBased	0.188104446729012	5	194628	521
qHTS Assay for NPC1 Promoter Activators	neutrophil count	NPC1	pathwayBased	0.519531683761622	21	320682	7575
HTS Assay for Inhibitors of Akt Phophorylation: Primary Screen	neutrophil count	AKT1_inhibitors	targetBased	0.27280896552834	5	356517	1139
Luminescence Cell-Based Primary HTS to Identify Inhibitors of A1 Apoptosis.	neutrophil count	BCL2L11_inhibitors	targetBased	0.471834415755603	16	325630	216
Dyrk1 A HTS Measured in Biochemical System Using Plate Reader - 2124-01_Inhibitor_SinglePoint_HTS_Activity	neutrophil count	DYRK1A_inhibitors	targetBased	0.405141891290698	9	310014	1321
uHTS Luminescent assay for identification of inhibitors of NALP3 in yeast	neutrophil count	NLRP3	targetBased	0.517196008031586	27	330392	1295
Fluorescence-based primary biochemical high throughput screening assay to identify inhibitors of human diacylglycerol lipase, beta (DAGLB)	neutrophil count	DAGLB_inhibitors	targetBased	0.459706939617906	17	343468	202
Luminescence-based cell-based primary high throughput screening assay to identify biased ligands of the melanocortin 4 receptor (MC4R): agonists of MC4R	neutrophil count	MC4R	targetBased	0.2861068819237	5	356160	3470
TRFRET-based cell-based primary high throughput screening assay to identify biased ligands of the melanocortin 4 receptor (MC4R): antagonists of MC4R	neutrophil count	MC4R	targetBased	0.2861068819237	5	356160	1703
HTS for Beta-2AR agonists via FAP method	neutrophil count	ADRB2_activators	targetBased	0.493029403178409	14	339297	1446
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	neutrophil count	FGB_inhibitors	targetBased	0.541800422744609	11	369953	760
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	neutrophil count	FGB_inhibitors	targetBased	0.541800422744609	11	369953	498
qHTS screen for small molecules that induce genotoxicity in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1	neutrophil count	ATAD5_inhibitors	targetBased	0.245665851467194	5	330109	4174
qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1	neutrophil count	ATAD5_inhibitors	targetBased	0.245665851467194	5	330107	7652
qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding	neutrophil count	MAPT	pathwayBased	0.26352460116028	8	267412	5703
qHTS Assay for Tau Filament Binding	neutrophil count	MAPT	targetBased	0.26352460116028	8	69668	1391
qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization	neutrophil count	MAPT	pathwayBased	0.26352460116028	8	271402	1048
AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of microphthalmia-associated transcription factor (MITF)	neutrophil count	MITF inhibitors	targetBased	0.468697864270438	6	642362	5830
MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Inhibitor_SinglePoint_HTS_Activity	neutrophil count	MITF	targetBased	0.468697864270438	6	331360	2760
Alphascreen assay for small molecules abrogating mHTT-CaM Interaction	neutrophil count	HTT	targetBased	0.398280617189308	10	189882	6790
Primary qHTS for Identification of Small Molecule Inhibitors of Huntingtin Promoter Activity	neutrophil count	HTT	targetBased	0.398280617189308	10	48068	449
qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Aggregate Formation (GFP)	neutrophil count	HTT	targetBased	0.398280617189308	10	220571	2380
qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Cytoprotection (ATP)	neutrophil count	HTT	targetBased	0.398280617189308	10	223611	305
Primary qHTS for Inhibitors of ATXN expression	neutrophil count	ATXN2_repressors	targetBased	0.279074066267336	14	358434	2554
Primary HTS Assay for S1P3 Antagonists	neutrophil count	S1PR3	targetBased	0.355152574443463	5	169141	462
Primary Cell-Based High-Throughput Screening to Identify Agonists of the Sphingosine 1-phosphate receptor 2 (S1P2)	neutrophil count	S1PR2	targetBased	0.443953834462638	17	96879	447
Primary Cell-Based High-Throughput Screening to Identify Antagonists of the Sphingosine 1-phosphate receptor 2 (S1P2)	neutrophil count	S1PR2	targetBased	0.443953834462638	17	96879	207
FRET-based HTS for detection of RAD52 Inhibitors Measured in Biochemical System Using Plate Reader - 7018-01_Inhibitor_SinglePoint_HTS_Activity_Set2	eosinophil count	RAD52	targetBased	0.324576702498839	4	352074	1608
HTS for developing T Cell Immune Modulators	eosinophil count	ITGAL	targetBased	0.172917873856873	7	326271	221
High Content Assay for Compounds that inhibit the Assembly of the Perinucleolar Compartment	eosinophil count	PTBP1	targetBased	0.307326409510085	7	139718	4338
Fluorescence-based primary biochemical high throughput screening assay to identify inhibitors of Protein Phosphatase 5 (PP5).	eosinophil count	PPP5C	targetBased	0.362850840088223	7	314999	564
Primary Cell-based High Throughput Screening assay for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA)	eosinophil count	RORA	pathwayBased	0.499649094840094	18	64908	979
Primary Cell-based High Throughput Screening assay for inhibitors of the Retinoic Acid Receptor-related orphan receptor A (RORA)	eosinophil count	RORA	pathwayBased	0.499649094840094	18	64908	278
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	eosinophil count	JAK2	targetBased	0.563353850272379	31	217959	2390
ROC1-CUL1 CTD Inhibitor di-Ub FRET Primary HTS Screen	eosinophil count	RBX1	targetBased	0.209134452658494	11	143816	859
qHTS for Inhibitors of Polymerase Iota	eosinophil count	POLI	targetBased	0.292814816776386	4	386063	3989
qHTS Assay for Inhibitors of the CtBP/E1A Interaction	eosinophil count	RBBP8	targetBased	0.317898927319209	11	335214	1652
Luminescence-based primary cell-based high throughput screening assay to identify activators of the Aryl Hydrocarbon Receptor (AHR)	eosinophil count	AHR_activators	targetBased	0.471196502487462	12	324747	7988
Fluorescence Biochemical Primary HTS to Identify Inhibitors of GASC-1 Activity	eosinophil count	KDM4C	targetBased	0.339156144692516	11	326066	228
High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Primary Screen	eosinophil count	NFKB1	pathwayBased	0.513404591520698	15	193265	3100
uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay	eosinophil count	NFKB1	pathwayBased	0.513404591520698	15	359244	3094
qHTS of IL-2 Activators	eosinophil count	IL2	targetBased	0.347575602955471	14	364617	238
Inhibitors of the vitamin D receptor (VDR): qHTS	eosinophil count	VDR	targetBased	0.396721692621007	5	394050	3624
uHTS identification of small molecule antagonists of the CCR6 receptor via a luminescent beta-arrestin assay	eosinophil count	CCR6_antagonists	targetBased	0.455006085257892	7	340696	1654
HTS for Identification of VLA-4 Allosteric Modulators from MLPCN library	eosinophil count	ITGA4	targetBased	0.514078667291535	14	326888	645
Primary cell-based high throughput screening assay to measure STAT1 activation	eosinophil count	STAT1 activation	pathwayBased	0.441066016124972	10	195980	5134
Primary cell-based high throughput screening assay to measure STAT1 inhibition	eosinophil count	STAT1	targetBased	0.441066016124972	10	195980	695
Small-molecule inhibitors of ST2 (IL1RL1)	eosinophil count	IL1RL1	targetBased	0.546168104715194	45	75924	1804
uHTS identification of Caspase-8 TRAIL sensitizers in a luminesence assay	eosinophil count	TNFRSF10B	targetBased	0.355161639026691	9	363840	3764
Antagonist identification of Pyk2 oligomerization: high-throughput screening cellular assay	eosinophil count	Pyk2Ã‚Â	targetBased	0.275540948371089	9	98749	818
Primary cell-based high-throughput screening assay for identification of compounds that inhibit/block inward-rectifying potassium ion channel Kir2.1	eosinophil count	KCNJ2	targetBased	0.442604052037998	12	305610	2592
Primary cell-based high-throughput screening for identification of compounds that inhibit/block calcium-activated chloride channels (TMEM16A)	eosinophil count	ANO1_inhibitors	targetBased	0.391620662177737	11	306502	3633
Primary cell-based high-throughput screening for identification of compounds that activate/potentiate calcium-activated chloride channels (TMEM16A)	eosinophil count	ANO1_activators	targetBased	0.391620662177737	11	335180	1022
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	eosinophil count	PPARG	targetBased	0.529196236886013	22	99314	335
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	eosinophil count	PPARG	targetBased	0.529196236886013	22	196176	782
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	eosinophil count	PPARG	targetBased	0.529196236886013	22	99314	390
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	eosinophil count	PPARG	targetBased	0.529196236886013	22	196177	811
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	eosinophil count	PPARG	targetBased	0.529196236886013	22	196176	670
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	eosinophil count	PPARG	targetBased	0.529196236886013	22	196177	519
qHTS for Activators of Integrin-Mediated Alleviation for Muscular Dystrophy	eosinophil count	CGA_integrin_activators	targetBased	0.373269957040284	11	345855	222
QFRET-based biochemical primary high throughput screening assay to identify exosite inhibitors of ADAM10.	eosinophil count	ADAM10_inhibitors	targetBased	0.285044838019891	6	369953	2294
uHTS Luminescent assay for identification of inhibitors of Sentrin-specific protease 7 (SENP7)	eosinophil count	SENP7	targetBased	0.372957397933451	8	331670	4902
Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bfl-1	eosinophil count	BCL2A1_modulators	targetBased	0.490995693506525	19	194826	237
High Content Assay for Compounds that inhibit the Assembly of the Perinucleolar Compartment	aspartate aminotransferase measurement	PTBP1	targetBased	0.344696636025509	6	139718	4338
Primary Cell-based High Throughput Screening assay for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA)	aspartate aminotransferase measurement	RORA	pathwayBased	0.297859731100656	6	64908	979
Primary Cell-based High Throughput Screening assay for inhibitors of the Retinoic Acid Receptor-related orphan receptor A (RORA)	aspartate aminotransferase measurement	RORA	pathwayBased	0.297859731100656	6	64908	278
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype	aspartate aminotransferase measurement	RAB2A	targetBased	0.327086018996593	5	194628	365
qHTS for Inhibitors of TGF-b	aspartate aminotransferase measurement	TGFB1	pathwayBased	0.288492676323418	5	403345	4970
uHTS for the identification of compounds that potentiate TRAIL-induced apoptosis of cancer cells	aspartate aminotransferase measurement	TNFSF10	targetBased	0.51056837906566	8	217035	883
qHTS Assay for Inhibitors of BAZ2B	aspartate aminotransferase measurement	BAZ2B_modulators	targetBased	0.166157923242819	8	356826	15709
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of myeloid cell leukemia sequence 1 (MCL1) interactions with BIM-BH3 peptide.	eosinophil count	MCL1	targetBased	0.189970230625587	23	314998	2139
uHTS of Mcl-1/Bid interaction inhibitors	eosinophil count	MCL1	targetBased	0.189970230625587	23	218602	2129
uHTS of Mcl-1/Noxa interaction inhibitors	eosinophil count	MCL1	targetBased	0.189970230625587	23	217330	3334
qHTS Assay for Identifying a Potential Treatment of Ataxia-Telangiectasia	eosinophil count	ATM_modulators	targetBased	0.417576790463838	14	322361	619
Fluorescence-based biochemical high throughput primary assay to identify inhibitors of phospholipase C isozymes (PLC-beta3).	eosinophil count	PLCB3	targetBased	0.132253421427145	12	369953	662
Luminescence Cell-Based Primary HTS to Identify Inhibitors of A1 Apoptosis.	eosinophil count	BCL2L11_inhibitors	targetBased	0.467646171587112	27	325630	216
Dyrk1 A HTS Measured in Biochemical System Using Plate Reader - 2124-01_Inhibitor_SinglePoint_HTS_Activity	eosinophil count	DYRK1A_inhibitors	targetBased	0.413798479562926	13	310014	1321
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb via a fluorescence resonance energy transfer (FRET) assay.	eosinophil count	RUNX1	targetBased	0.317215116550536	53	215667	993
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay.	eosinophil count	RUNX1	targetBased	0.317215116550536	53	218234	1620
qHTS Assay for Inhibitors of 15-hLO (15-human lipoxygenase)	eosinophil count	ALOX15_inhibitors	targetBased	0.724336231239081	52	73174	1034
Primary HTS assay for chemical inhibitors of TNF alpha stimulated VCAM1 expression	eosinophil count	VCAM1_expression	targetBased	0.42878930350103	8	94498	457
qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)	eosinophil count	HPGD	targetBased	0.31795351698338	4	148480	6428
HTS of Smad transcription factor inhibitors	eosinophil count	SMAD3	targetBased	0.562408491365278	42	88033	251
HTS for Beta-2AR agonists via FAP method	eosinophil count	ADRB2_activators	targetBased	0.541528896921096	26	339297	1446
uHTS identification of small molecule antagonists of the EBI2 receptor via a luminescent beta-arrestin assay	eosinophil count	GPR183	targetBased	0.239594993132693	22	363840	2946
Primary HTS and Confirmation Assays for S1P1 Agonists and Agonism Potentiators	eosinophil count	S1PR1	targetBased	0.492139451390074	24	55710	315
Primary biochemical high throughput screening assay to identify inhibitors of BCL2-related protein, long isoform (BCLXL).	eosinophil count	BCL2L1_modulators	targetBased	0.417624868110512	8	314998	2199
qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding	eosinophil count	MAPT	pathwayBased	0.168440477134908	8	267412	5703
qHTS Assay for Tau Filament Binding	eosinophil count	MAPT	targetBased	0.168440477134908	8	69668	1391
qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization	eosinophil count	MAPT	pathwayBased	0.168440477134908	8	271402	1048
Inhibitors of Cav3 T-type Calcium Channels: Primary Screen	eosinophil count	CACNA1H_inhibitors	targetBased	0.379883827884797	9	104728	4230
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	aspartate aminotransferase measurement	PPARG	targetBased	0.492254693878048	9	99314	335
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	aspartate aminotransferase measurement	PPARG	targetBased	0.492254693878048	9	196176	782
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	aspartate aminotransferase measurement	PPARG	targetBased	0.492254693878048	9	99314	390
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	aspartate aminotransferase measurement	PPARG	targetBased	0.492254693878048	9	196177	811
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	aspartate aminotransferase measurement	PPARG	targetBased	0.492254693878048	9	196176	670
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	aspartate aminotransferase measurement	PPARG	targetBased	0.492254693878048	9	196177	519
uHTS Fluorescent assay for identification of inhibitors of hexokinase domain containing I (HKDC1)	aspartate aminotransferase measurement	HKDC1	targetBased	0.467343720004769	6	340696	540
uHTS Luminescent assay for identification of inhibitors of NALP3 in yeast	aspartate aminotransferase measurement	NLRP3	targetBased	0.406064748076444	6	330392	1295
Acumen qHTS Assay for Inhibitors of the mTORC1 Signaling Pathway in MEF (Tsc2-/-, p53-/-) Cells: Sytravon	aspartate aminotransferase measurement	MTOR	pathwayBased	0.238026339924844	5	43989	342
Primary qHTS for Inhibitors of ATXN expression	aspartate aminotransferase measurement	ATXN2_repressors	targetBased	0.182073644635135	5	358434	2554
uHTS for identification of Inhibitors of Mdm2/MdmX interaction in luminescent format.	eosinophil count	MDM4	targetBased	0.371267225992662	7	331671	10022
Primary qHTS for Inhibitors of ATXN expression	eosinophil count	ATXN2_repressors	targetBased	0.308730203957558	19	358434	2554
Primary Cell-Based Assay to Identify Agonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	eosinophil count	S1PR4	targetBased	0.669089535404003	25	217959	771
Primary Cell-Based Assay to Identify Antagonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	eosinophil count	S1PR4	targetBased	0.669089535404003	25	217959	569
HTS for developing T Cell Immune Modulators	basophil count	ITGAL	targetBased	0.310961884091902	6	326271	221
ROC1-CUL1 CTD Inhibitor di-Ub FRET Primary HTS Screen	basophil count	RBX1	targetBased	0.196323043971028	7	143816	859
Identification of Molecular Probes that Activate MRP-1	basophil count	ABCC1_activators	targetBased	0.458619852560533	8	138717	842
High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Primary Screen	basophil count	NFKB1	pathwayBased	0.468851296207009	7	193265	3100
uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay	basophil count	NFKB1	pathwayBased	0.468851296207009	7	359244	3094
HTS for Identification of VLA-4 Allosteric Modulators from MLPCN library	basophil count	ITGA4	targetBased	0.495136212351612	11	326888	645
Primary Cell-based High Throughput Screening assay for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA)	blood urea nitrogen measurement	RORA	pathwayBased	0.485862842824816	6	64908	979
Primary Cell-based High Throughput Screening assay for inhibitors of the Retinoic Acid Receptor-related orphan receptor A (RORA)	blood urea nitrogen measurement	RORA	pathwayBased	0.485862842824816	6	64908	278
qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS	blood urea nitrogen measurement	GNAS	targetBased	0.342232287742262	6	334825	423
qHTS for Antagonists of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS	blood urea nitrogen measurement	GNAS	targetBased	0.342232287742262	6	337446	1356
HTS for PAX8 inhibitors using PAX8 luciferase reporter gene assay in RMG-I cells Measured in Cell-Based System Using Plate Reader - 7054-01_Inhibitor_SinglePoint_HTS_Activity	blood urea nitrogen measurement	PAX8	targetBased	0.479173864110967	8	353950	4145
Primary Cell-based High Throughput Screening assay for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA)	protein measurement	RORA	pathwayBased	0.528788155725603	31	64908	979
Primary Cell-based High Throughput Screening assay for inhibitors of the Retinoic Acid Receptor-related orphan receptor A (RORA)	protein measurement	RORA	pathwayBased	0.528788155725603	31	64908	278
Primary cell-based high-throughput screening for identification of compounds that inhibit/block calcium-activated chloride channels (TMEM16A)	basophil count	ANO1_inhibitors	targetBased	0.312809599112641	5	306502	3633
Primary cell-based high-throughput screening for identification of compounds that activate/potentiate calcium-activated chloride channels (TMEM16A)	basophil count	ANO1_activators	targetBased	0.312809599112641	5	335180	1022
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	basophil count	PPARG	targetBased	0.147499456763898	6	99314	335
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	basophil count	PPARG	targetBased	0.147499456763898	6	196176	782
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	basophil count	PPARG	targetBased	0.147499456763898	6	99314	390
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	basophil count	PPARG	targetBased	0.147499456763898	6	196177	811
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	basophil count	PPARG	targetBased	0.147499456763898	6	196176	670
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	basophil count	PPARG	targetBased	0.147499456763898	6	196177	519
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of myeloid cell leukemia sequence 1 (MCL1) interactions with BIM-BH3 peptide.	basophil count	MCL1	targetBased	0.170979404817765	8	314998	2139
uHTS of Mcl-1/Bid interaction inhibitors	basophil count	MCL1	targetBased	0.170979404817765	8	218602	2129
uHTS of Mcl-1/Noxa interaction inhibitors	basophil count	MCL1	targetBased	0.170979404817765	8	217330	3334
Dyrk1 A HTS Measured in Biochemical System Using Plate Reader - 2124-01_Inhibitor_SinglePoint_HTS_Activity	basophil count	DYRK1A_inhibitors	targetBased	0.277007781952663	4	310014	1321
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb via a fluorescence resonance energy transfer (FRET) assay.	basophil count	RUNX1	targetBased	0.218769764145573	6	215667	993
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay.	basophil count	RUNX1	targetBased	0.218769764145573	6	218234	1620
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of Protein Arginine Deiminase 4 (PAD4) (1536 HTS)	basophil count	PADI4	targetBased	0.445671604056542	7	326022	1334
Primary qHTS for Inhibitors of ATXN expression	basophil count	ATXN2_repressors	targetBased	0.261689918232741	12	358434	2554
FRET-based HTS for detection of RAD52 Inhibitors Measured in Biochemical System Using Plate Reader - 7018-01_Inhibitor_SinglePoint_HTS_Activity_Set2	monocyte count	RAD52	targetBased	0.153450071617547	7	352074	1608
HTS for developing T Cell Immune Modulators	monocyte count	ITGAL	targetBased	0.397350940260214	11	326271	221
Identification of agents that induce E-selectin on human endothelial cells Measured in Cell-Based System Using Imaging - 2152-01_Activator_SinglePoint_HTS_Activity	monocyte count	SELE	targetBased	0.282133542098412	6	257988	963
Primary HTS assay for chemical inhibitors of TNF alpha stimulated E-Selectin expression	monocyte count	E-selectinExpression	targetBased	0.282133542098412	6	118096	843
High Content Assay for Compounds that inhibit the Assembly of the Perinucleolar Compartment	monocyte count	PTBP1	targetBased	0.323951311133853	5	139718	4338
HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Inhibitor_SinglePoint_HTS_Activity	monocyte count	SCARB1	targetBased	0.466979250405268	6	319204	3065
HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Activator_SinglePoint_HTS_Activity	monocyte count	SCARB1	targetBased	0.466979250405268	6	316970	306
HTS to identify compounds that promote myeloid differentiation with MLPCN compound set	monocyte count	HOXA9	pathwayBased	0.371155163682581	12	358556	3721
Luminescence-based cell-based primary high throughput screening assay to identify inhibitors of the Steroid Receptor Coactivator 1 (SRC1; NCOA1)	monocyte count	NCOA1	targetBased	0.389801245667997	5	359206	428
Primary cell-based high throughput screening assay to identify inhibitors of kruppel-like factor 5 (KLF5)	monocyte count	KLF5	targetBased	0.413433757281229	8	290726	671
Luminescence-based cell-based primary high throughput screening assay to identify activators of the function of SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 (SMARCA2, BRM)	protein measurement	SMARCA2	targetBased	0.313167775465899	6	368927	3838
Factor XIa 1536 HTS	protein measurement	F11_modulation	targetBased	0.33026632451569	36	218707	302
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	protein measurement	JAK2	targetBased	0.272942621808993	48	217959	2390
Identification of CBX7 inhibitors - Primary Alpha Screen	protein measurement	Chromobox protein homolog 7 inhibitors	targetBased	0.344312548332388	5	64999	724
Luminescence-based cell-based primary high throughput screening assay to identify agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A)	protein measurement	HTR2A	targetBased	0.140073870269378	5	363803	2412
Primary cell-based high throughput screening assay to identify inhibitors of kruppel-like factor 5 (KLF5)	protein measurement	KLF5	targetBased	0.234667103487265	7	290726	671
Fluorescence-based cell-based primary high throughput screening assay to identify inhibitors of the interaction of nucleotide-binding oligomerization domain containing 2 (NOD2) and the receptor-interacting serine-threonine kinase 2 (RIPK2)	protein measurement	RIPK2	targetBased	0.363178995094251	4	363803	1383
Luminescence-based primary cell-based high throughput screening assay to identify activators of the Aryl Hydrocarbon Receptor (AHR)	protein measurement	AHR_activators	targetBased	0.265439065772347	12	324747	7988
Fluorescence Biochemical Primary HTS to Identify Inhibitors of GASC-1 Activity	protein measurement	KDM4C	targetBased	0.237877593481899	15	326066	228
Cell-based coincidence reporter assay to measure PMP22 gene transcription in S16 Pmp22-F2sN cells - Primary screen	protein measurement	PMP22	targetBased	0.210762446742684	4	42576	834
Primary cell-based high throughput screening assay to measure STAT1 activation	protein measurement	STAT1 activation	pathwayBased	0.351534194342969	7	195980	5134
Primary cell-based high throughput screening assay to measure STAT1 inhibition	protein measurement	STAT1	targetBased	0.351534194342969	7	195980	695
Small-molecule inhibitors of ST2 (IL1RL1)	protein measurement	IL1RL1	targetBased	0.313964993706358	23	75924	1804
uHTS identification of HIF-2a Inhibitors in a luminesence assay	protein measurement	HIF-2a_inhibitors	targetBased	0.211647975730091	32	363840	2624
Novel sEH inhibitors for the therapeutic treatment of hypertension and inflammation	protein measurement	sEH_inhibitors	targetBased	0.384519865726853	8	90640	310
qHTS for Inhibitors of Polymerase Kappa	protein measurement	POLK	targetBased	0.113874808939767	22	395295	2034
qHTS Assay for Inhibitors of RGS12 GoLoco Motif Activity (Red Fluorophore)	protein measurement	GNAI1	targetBased	0.346916624225194	4	229888	1007
Factor XIIa 1536 HTS	protein measurement	F12_modulation	targetBased	0.178153692428762	26	217430	649
Primary cell-based high-throughput screening for identification of compounds that inhibit/block calcium-activated chloride channels (TMEM16A)	protein measurement	ANO1_inhibitors	targetBased	0.293010979076048	4	306502	3633
Primary cell-based high-throughput screening for identification of compounds that activate/potentiate calcium-activated chloride channels (TMEM16A)	protein measurement	ANO1_activators	targetBased	0.293010979076048	4	335180	1022
Primary cell-based high-throughput screening assay for identification of compounds that allosterically potentiate transient receptor potential cation channel C4 (TRPC4)	protein measurement	TRPC4	targetBased	0.371185464686355	5	305600	1291
Primary cell-based screen for identification of compounds that activate transient receptor potential cation channel C4 (TRPC4).	protein measurement	TRPC4	targetBased	0.371185464686355	5	305600	1510
Primary cell-based screen for identification of compounds that inhibit transient receptor potential cation channel C4 (TRPC4).	protein measurement	TRPC4	targetBased	0.371185464686355	5	304001	1189
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac activated mutant	protein measurement	RAC1	targetBased	0.133376304407961	17	194629	219
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac wildtype	protein measurement	RAC1	targetBased	0.133376304407961	17	194628	521
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of the prolyl oligopeptidase-like enzyme (PREPL)	protein measurement	PREPL	targetBased	0.372483325365511	8	324747	2221
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype	monocyte count	RAB2A	targetBased	0.417616083612416	8	194628	365
Luminescence-based primary cell-based high throughput screening assay to identify activators of the Aryl Hydrocarbon Receptor (AHR)	monocyte count	AHR_activators	targetBased	0.429082130876573	10	324747	7988
High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Primary Screen	monocyte count	NFKB1	pathwayBased	0.500249908552602	11	193265	3100
uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay	monocyte count	NFKB1	pathwayBased	0.500249908552602	11	359244	3094
HTS for Identification of VLA-4 Allosteric Modulators from MLPCN library	monocyte count	ITGA4	targetBased	0.563653416927251	46	326888	645
uHTS identification of Caspase-8 TRAIL sensitizers in a luminesence assay	monocyte count	TNFRSF10B	targetBased	0.306527183993248	5	363840	3764
Antagonist identification of Pyk2 oligomerization: high-throughput screening cellular assay	monocyte count	Pyk2Ã‚Â	targetBased	0.348652108541954	8	98749	818
uHTS for the identification of compounds that potentiate TRAIL-induced apoptosis of cancer cells	monocyte count	TNFSF10	targetBased	0.464870516017249	11	217035	883
qHTS Assay for Inhibitors of BAZ2B	monocyte count	BAZ2B_modulators	targetBased	0.43865244331566	8	356826	15709
Primary cell-based high-throughput screening assay for identification of compounds that inhibit/block inward-rectifying potassium ion channel Kir2.1	monocyte count	KCNJ2	targetBased	0.475545913097939	6	305610	2592
Primary Cell-Based Assay to Identify Agonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	monocyte count	S1PR4	targetBased	0.665324642173597	28	217959	771
Primary Cell-Based Assay to Identify Antagonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	monocyte count	S1PR4	targetBased	0.665324642173597	28	217959	569
Fluorescence-based biochemical primary high throughput screening assay to identify activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF)	monocyte count	TNNI3	targetBased	0.281742131529481	7	335239	801
Fluorescence-based biochemical primary high throughput screening assay to identify inhibitors of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF)	monocyte count	TNNI3	targetBased	0.281742131529481	7	335238	390
uHTS identification of DNMT1 inhibitors in a Fluorescent Molecular Beacon assay	monocyte count	DNMT1	targetBased	0.194807807935997	6	359244	2975
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	monocyte count	PPARG	targetBased	0.400355899047012	13	99314	335
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	monocyte count	PPARG	targetBased	0.400355899047012	13	196176	782
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	monocyte count	PPARG	targetBased	0.400355899047012	13	99314	390
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	monocyte count	PPARG	targetBased	0.400355899047012	13	196177	811
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	monocyte count	PPARG	targetBased	0.400355899047012	13	196176	670
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	monocyte count	PPARG	targetBased	0.400355899047012	13	196177	519
High throughput screening of activators of transient receptor potential cation channel C6 (TRPC6)	monocyte count	TRPC6	targetBased	0.445060762125922	5	305610	382
High throughput screening of inhibitors of transient receptor potential cation channel C6 (TRPC6)	monocyte count	TRPC6	targetBased	0.445060762125922	5	305610	3253
Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bfl-1	monocyte count	BCL2A1_modulators	targetBased	0.493471306702511	25	194826	237
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of myeloid cell leukemia sequence 1 (MCL1) interactions with BIM-BH3 peptide.	monocyte count	MCL1	targetBased	0.283606592830717	22	314998	2139
uHTS of Mcl-1/Bid interaction inhibitors	monocyte count	MCL1	targetBased	0.283606592830717	22	218602	2129
uHTS of Mcl-1/Noxa interaction inhibitors	monocyte count	MCL1	targetBased	0.283606592830717	22	217330	3334
qHTS Assay for Identifying a Potential Treatment of Ataxia-Telangiectasia	monocyte count	ATM_modulators	targetBased	0.212607922692282	5	322361	619
Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2	monocyte count	THRB	targetBased	0.495423431799353	8	276265	806
Luminescence Cell-Based Primary HTS to Identify Inhibitors of A1 Apoptosis.	monocyte count	BCL2L11_inhibitors	targetBased	0.525053140584303	46	325630	216
Primary screen for compounds that inhibit Alzheimer's amyloid precursor protein (APP) translation	protein measurement	APP_inhibitors	pathwayBased	0.338814451403948	8	193714	1590
Primary screen for compounds that activate Alzheimer's amyloid precursor	protein measurement	APP_inhibitors	pathwayBased	0.338814451403948	8	193400	1987
qHTS for compounds that reverse cellular toxicity of Amyloid beta (A-beta) peptide in yeast: Primary Screen	protein measurement	APP_inhibitors	targetBased	0.338814451403948	8	404343	257
uHTS identification of small molecule inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase, LMPTP, via a fluorescence intensity assay	protein measurement	ACP1_inhibitors	targetBased	0.288862746471843	13	363840	817
Inhibitors of CDC25B-CDK2/CyclinA interaction	protein measurement	Inhibitors of CDC25B-CDK2/CyclinA interaction	targetBased	0.164800915676453	5	93798	679
Primary qHTS for Inhibitors of N-terminal methyltransferase 1 (NTMT1): MTaseGlo Assay	protein measurement	NTMT1	targetBased	0.149315429342369	7	56440	1336
qHTS for Inhibitors of phosphatidylinositol 5-phosphate 4-kinase (PI5P4K)	protein measurement	PIP4K2A	targetBased	0.182652552459702	4	328860	4078
High throughput discovery of novel modulators of ROMK K+ channel activity: Primary Screen	protein measurement	KCNJ1	targetBased	0.383059270898686	23	125268	2463
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb via a fluorescence resonance energy transfer (FRET) assay.	protein measurement	RUNX1	targetBased	0.324820737799212	22	215667	993
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay.	protein measurement	RUNX1	targetBased	0.324820737799212	22	218234	1620
HTS identification of compounds inhibiting the binding of CD11b/CD18 to fibrinogen via a luminescence assay.	protein measurement	ITGB2	targetBased	0.326834356860367	16	92518	501
uHTS identification of TNAP inhibitors in the absence of phosphate acceptor performed in luminescent assay	protein measurement	ALPL_inhibitors	targetBased	0.279322153377645	36	195560	517
MLPCN ERAP1 Measured in Biochemical System Using Plate Reader - 7016-01_Inhibitor_SinglePoint_HTS_Activity	protein measurement	ERAP1_inhibitors	targetBased	0.438162281302377	11	335777	499
Luminescence-based cell-based primary high throughput screening assay to identify biased ligands of the melanocortin 4 receptor (MC4R): agonists of MC4R	protein measurement	MC4R	targetBased	0.347356027368734	19	356160	3470
TRFRET-based cell-based primary high throughput screening assay to identify biased ligands of the melanocortin 4 receptor (MC4R): antagonists of MC4R	protein measurement	MC4R	targetBased	0.347356027368734	19	356160	1703
High Throughput Imaging Assay for Beta-Catenin	protein measurement	betaCateninTranslocation	targetBased	0.249170000656941	35	193542	587
Primary cell-based screen for identification of compounds that inhibit the two-pore domain potassium channel KCNK9	protein measurement	KCNK9_blockers	targetBased	0.557707909379901	37	305610	3794
Inhibition of the MLL-AF4-AF9 Interaction in Pediatric Leukemia Measured in Biochemical System Using Plate Reader - 2160-01_Inhibitor_SinglePoint_HTS_Activity	protein measurement	MLLT3	targetBased	0.437620926942274	8	344459	1627
TRFRET-based cell-based primary high throughput screening assay to identify inhibitors of cell surface Prion Protein (PRPC)	protein measurement	PRNP	targetBased	0.159560247876443	8	369953	1596
Primary HTS assay for 5-Hydroxytryptamine (Serotonin) Receptor Subtype 1a (5HT1a) agonists	protein measurement	HTR1A	targetBased	0.188901172468044	5	64908	366
Primary HTS assay for 5-Hydroxytryptamine (Serotonin) Receptor Subtype 1a (5HT1a) antagonists	protein measurement	HTR1A	targetBased	0.188901172468044	5	61606	416
Assay for HTS of Gi/Go-linked GPCRs using mGluR8: Primary Screening	protein measurement	GRM8	targetBased	0.321937235385062	4	105151	2166
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb via a fluorescence resonance energy transfer (FRET) assay.	monocyte count	RUNX1	targetBased	0.321114124819052	19	215667	993
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay.	monocyte count	RUNX1	targetBased	0.321114124819052	19	218234	1620
Primary HTS assay for chemical inhibitors of TNF alpha stimulated VCAM1 expression	monocyte count	VCAM1_expression	targetBased	0.458602028607504	14	94498	457
Fluorescence-based primary biochemical high throughput screening assay to identify inhibitors of human diacylglycerol lipase, beta (DAGLB)	monocyte count	DAGLB_inhibitors	targetBased	0.499609959899103	18	343468	202
Primary biochemical high-throughput screening assay to measure P97 ATPase inhibition	monocyte count	VCP	targetBased	0.343814132877469	6	217959	923
Primary biochemical high throughput screening assay to identify inhibitors of BCL2-related protein, long isoform (BCLXL).	monocyte count	BCL2L1_modulators	targetBased	0.245727104799484	9	314998	2199
Thrombin 1536 HTS	monocyte count	F2_modulation	targetBased	0.442817433795985	8	217233	557
Primary qHTS for Inhibitors of ATXN expression	monocyte count	ATXN2_repressors	targetBased	0.317236780727411	14	358434	2554
Primary HTS Assay for S1P3 Antagonists	monocyte count	S1PR3	targetBased	0.583242928597541	38	169141	462
Primary Cell-Based High-Throughput Screening to Identify Agonists of the Sphingosine 1-phosphate receptor 2 (S1P2)	monocyte count	S1PR2	targetBased	0.56162009245327	10	96879	447
Primary Cell-Based High-Throughput Screening to Identify Antagonists of the Sphingosine 1-phosphate receptor 2 (S1P2)	monocyte count	S1PR2	targetBased	0.56162009245327	10	96879	207
Luminescence Cell-Based Primary HTS to Identify Inhibitors of A1 Apoptosis.	basophil count	BCL2L11_inhibitors	targetBased	0.256823338920726	6	325630	216
qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding	protein measurement	MAPT	pathwayBased	0.290867389031879	31	267412	5703
qHTS Assay for Tau Filament Binding	protein measurement	MAPT	targetBased	0.290867389031879	31	69668	1391
qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization	protein measurement	MAPT	pathwayBased	0.290867389031879	31	271402	1048
Alphascreen assay for small molecules abrogating mHTT-CaM Interaction	protein measurement	HTT	targetBased	0.372654369245121	12	189882	6790
Primary qHTS for Identification of Small Molecule Inhibitors of Huntingtin Promoter Activity	protein measurement	HTT	targetBased	0.372654369245121	12	48068	449
qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Aggregate Formation (GFP)	protein measurement	HTT	targetBased	0.372654369245121	12	220571	2380
qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Cytoprotection (ATP)	protein measurement	HTT	targetBased	0.372654369245121	12	223611	305
uHTS identification of small molecule modulators of NR3A	protein measurement	GRIN3A	targetBased	0.242352072198315	6	339772	8480
MLPCN SirT-5 Measured in Biochemical System Using Imaging - 7044-01_Inhibitor_SinglePoint_HTS_Activity_Set5	aspartate aminotransferase measurement	SIRT5	targetBased	0.119078969559867	5	323507	3752
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of human platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (PAFAH1B2)	protein measurement	PAFAH1B2	targetBased	0.284714518989568	14	335239	4158
Factor XIa 1536 HTS	serum metabolite measurement	F11_modulation	targetBased	0.213597507574112	9	218707	302
Fluorescence Biochemical Primary HTS to Identify Inhibitors of GASC-1 Activity	serum metabolite measurement	KDM4C	targetBased	0.302814255814136	6	326066	228
Factor XIIa 1536 HTS	serum metabolite measurement	F12_modulation	targetBased	0.241670881067179	9	217430	649
HTS Assay for Activators of Cytochrome P450 2A9	serum metabolite measurement	CYP2C9_activators	targetBased	0.36742161700666	8	95858	1368
CYP2C9 Assay	serum metabolite measurement	CYP2C9_inhibitors	targetBased	0.36742161700666	8	95858	18730
Inhibitors of USP1/UAF1: Primary Screen	serum metabolite measurement	USP1	targetBased	0.172164370483049	48	389569	904
CYP2C19 Assay	serum metabolite measurement	CYP2C19_inhibitors	targetBased	0.352575248695856	8	95857	20295
qHTS Assay for the Inhibitors of Human Flap endonuclease 1 (FEN1).	serum metabolite measurement	FEN1_inhibitors	targetBased	0.107388474037863	336	386270	1331
Factor XIa 1536 HTS	blood metabolite measurement	F11_modulation	targetBased	0.192239664089508	5	218707	302
Identification of Molecular Probes that Activate MRP-1	blood metabolite measurement	ABCC1_activators	targetBased	0.463195219311354	6	138717	842
HTS Assay for Activators of Cytochrome P450 2A9	blood metabolite measurement	CYP2C9_activators	targetBased	0.416173256743795	5	95858	1368
CYP2C9 Assay	blood metabolite measurement	CYP2C9_inhibitors	targetBased	0.416173256743795	5	95858	18730
Identification of Small Molecule Correctors of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Delta508 Mutation Function in Human Bronchial Epithelial Cells. Measured in Cell-Based System Using Plate Reader - 7017-01_Other_SinglePoint_HTS_Activity	hematologic disease	cftrCorrectors	targetBased	0.137929141221939	78	343786	1253
Fluorescence Polarization with CAL-PDZ Measured in Biochemical System Using Plate Reader - 2109-02_Inhibitor_SinglePoint_HTS_Activity	hematologic disease	cftrTrafficModulators	targetBased	0.137929141221939	78	296501	2737
HTS to identify compounds that promote myeloid differentiation with MLPCN compound set	hematologic disease	HOXA9	pathwayBased	0.153845439130832	339	358556	3721
HTS for Tumor Hsp90 Inhibitors	hematologic disease	HSP90 known inhibitor displacement	targetBased	0.150439381940727	100	63696	220
Luminescence-based primary biochemical high throughput screening assay to identify inhibitors of the Heat Shock Protein 90 (HSP90)	hematologic disease	HSP90AA1	targetBased	0.150439381940727	100	290726	2649
qHTS assay for MDR1-selective chemotherapeutics: Primary screen using the drug-selected MDR subline cells KB-V1	hematologic disease	MDR1-selectiveÃ‚Â compounds	targetBased	0.170775721024682	656	396029	13426
qHTS assay for MDR1-selective chemotherapeutics: Primary screen using the parental adenocarcinoma cell KB-3-1	hematologic disease	MDR1-selectiveÃ‚Â compounds	targetBased	0.170775721024682	656	395981	5516
Factor XIa 1536 HTS	hematologic disease	F11_modulation	targetBased	0.416941715352259	284	218707	302
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	hematologic disease	JAK2	targetBased	0.756268849901468	5543	217959	2390
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of the interaction of the Ras and Rab interactor 1 protein (Rin1) and the c-abl oncogene 1, non-receptor tyrosine kinase (Abl)	hematologic disease	ABL1_interaction	targetBased	0.327033266899264	4591	359207	1432
Dicer-mediated maturation of pre-microRNA	hematologic disease	Dicer_inhibitors	targetBased	0.16642846891562	99	46715	2829
qHTS for Inhibitors of TGF-b	hematologic disease	TGFB1	pathwayBased	0.228946936481526	1224	403345	4970
EZH2/PRC2 methyltransferase inhibitors Measured in Biochemical System Using Plate Reader - 2125-01_Inhibitor_SinglePoint_HTS_Activity	hematologic disease	EZH2_inhibitors	targetBased	0.307822983381966	1120	57013	201
Luminescence-based primary cell-based high throughput screening assay to identify activators of the Aryl Hydrocarbon Receptor (AHR)	hematologic disease	AHR_activators	targetBased	0.162299508011869	148	324747	7988
High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Primary Screen	hematologic disease	NFKB1	pathwayBased	0.289149117260233	2557	193265	3100
uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay	hematologic disease	NFKB1	pathwayBased	0.289149117260233	2557	359244	3094
qHTS of IL-2 Activators	hematologic disease	IL2	targetBased	0.159308978229881	1510	364617	238
Development of Small Molecule Probes of the Histone Methyltransferase, NSD2 Measured in Biochemical System Using Plate Reader - 7053-01_Inhibitor_SinglePoint_HTS_Activity_Set2	hematologic disease	NSD2	targetBased	0.220863537463409	140	309684	1662
Inhibitors of the vitamin D receptor (VDR): qHTS	hematologic disease	VDR	targetBased	0.204819319033451	188	394050	3624
Toxoplasma gondii inhibition HTS in the presence of IFN-y	hematologic disease	IFNG	targetBased	0.175399996654986	2703	67275	2509
qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide	hematologic disease	Menin-MLL_inhibitors	targetBased	0.174661923632929	154	263421	615
qHTS Assay for NPC1 Promoter Activators	hematologic disease	NPC1	pathwayBased	0.305859664489525	1323	320682	7575
qHTS assay for re-activators of p53 using a Luc reporter	hematologic disease	TP53	pathwayBased	0.321643309276836	5102	321427	201
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Nonpermissive Temperature	hematologic disease	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.321643309276836	5102	54509	528
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Permissive Temperature	hematologic disease	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.321643309276836	5102	54513	338
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature	hematologic disease	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.321643309276836	5102	125394	1890
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Permissive Temperature	hematologic disease	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.321643309276836	5102	124022	1156
HTS Assay for Inhibitors of Akt Phophorylation: Primary Screen	hematologic disease	AKT1_inhibitors	targetBased	0.18411929476338	2013	356517	1139
qHTS Assay for Identifying a Potential Treatment of Ataxia-Telangiectasia	hematologic disease	ATM_modulators	targetBased	0.302107789202345	654	322361	619
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb via a fluorescence resonance energy transfer (FRET) assay.	hematologic disease	RUNX1	targetBased	0.340847332310171	4451	215667	993
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay.	hematologic disease	RUNX1	targetBased	0.340847332310171	4451	218234	1620
uHTS identification of TNAP inhibitors in the absence of phosphate acceptor performed in luminescent assay	hematologic disease	ALPL_inhibitors	targetBased	0.105859628078433	15	195560	517
Absorbance-based primary biochemical high throughput screening assay to identify activators of procaspase-3	hematologic disease	procaspase3Activators	targetBased	0.17602412017664	545	326024	350
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of HIV-1 LEDGF/p75 DNA Integration	hematologic disease	PSIP1	targetBased	0.168092336825364	29	369953	2353
High Throughput Imaging Assay for Beta-Catenin	hematologic disease	betaCateninTranslocation	targetBased	0.203797706605134	155	193542	587
Primary cell-based high throughput screening assay to measure STAT3 activation	hematologic disease	STAT3	pathwayBased	0.324185774456495	1884	194666	1772
Primary cell-based high throughput screening assay to measure STAT3 inhibition	hematologic disease	STAT3	pathwayBased	0.324185774456495	1884	194666	1722
Primary biochemical high throughput screening assay to identify inhibitors of BCL2-related protein, long isoform (BCLXL).	hematologic disease	BCL2L1_modulators	targetBased	0.145994802798864	718	314998	2199
Thrombin 1536 HTS	hematologic disease	F2_modulation	targetBased	0.321108383014022	1138	217233	557
Acumen qHTS Assay for Inhibitors of the mTORC1 Signaling Pathway in MEF (Tsc2-/-, p53-/-) Cells: Sytravon	hematologic disease	MTOR	pathwayBased	0.239593218807539	1343	43989	342
Identification of agents that induce E-selectin on human endothelial cells Measured in Cell-Based System Using Imaging - 2152-01_Activator_SinglePoint_HTS_Activity	blood protein measurement	SELE	targetBased	0.273258200289619	7	257988	963
Primary HTS assay for chemical inhibitors of TNF alpha stimulated E-Selectin expression	blood protein measurement	E-selectinExpression	targetBased	0.273258200289619	7	118096	843
Primary cell-based high-throughput screening assay for identification of compounds that inhibit KCNQ1 potassium channels	blood protein measurement	KCNQ1	targetBased	0.237882003885762	5	305610	3878
Primary cell-based high-throughput screening assay for identification of compounds that potentiate/activate KCNQ1 potassium channels	blood protein measurement	KCNQ1	targetBased	0.237882003885762	5	305610	1082
HTS for developing T Cell Immune Modulators	granulocyte count	ITGAL	targetBased	0.270659534983167	12	326271	221
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	granulocyte count	JAK2	targetBased	0.326957546638083	20	217959	2390
qHTS assay for MDR1-selective chemotherapeutics: Primary screen using the drug-selected MDR subline cells KB-V1	blood protein measurement	MDR1-selectiveÃ‚Â compounds	targetBased	0.293188860615053	5	396029	13426
qHTS assay for MDR1-selective chemotherapeutics: Primary screen using the parental adenocarcinoma cell KB-3-1	blood protein measurement	MDR1-selectiveÃ‚Â compounds	targetBased	0.293188860615053	5	395981	5516
HTS for Identification of VLA-4 Allosteric Modulators from MLPCN library	granulocyte count	ITGA4	targetBased	0.405516003721241	19	326888	645
qHTS Assay for Inhibitors of BAZ2B	granulocyte count	BAZ2B_modulators	targetBased	0.278168182754235	8	356826	15709
Primary Cell-Based Assay to Identify Agonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	granulocyte count	S1PR4	targetBased	0.441063490199147	30	217959	771
Primary Cell-Based Assay to Identify Antagonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	granulocyte count	S1PR4	targetBased	0.441063490199147	30	217959	569
uHTS identification of DNMT1 inhibitors in a Fluorescent Molecular Beacon assay	granulocyte count	DNMT1	targetBased	0.101371893146475	7	359244	2975
qHTS for Activators of Integrin-Mediated Alleviation for Muscular Dystrophy	granulocyte count	CGA_integrin_activators	targetBased	0.148873284445156	12	345855	222
USP8 deubiquitinase inhibition: Primary qHTS	granulocyte count	USP8	targetBased	0.115176133721693	4	47480	2010
qHTS Assay for NPC1 Promoter Activators	granulocyte count	NPC1	pathwayBased	0.350949558495311	12	320682	7575
qHTS Assay for Identifying a Potential Treatment of Ataxia-Telangiectasia	granulocyte count	ATM_modulators	targetBased	0.18309257687256	12	322361	619
Dyrk1 A HTS Measured in Biochemical System Using Plate Reader - 2124-01_Inhibitor_SinglePoint_HTS_Activity	granulocyte count	DYRK1A_inhibitors	targetBased	0.291166997806341	12	310014	1321
uHTS Luminescent assay for identification of inhibitors of NALP3 in yeast	granulocyte count	NLRP3	targetBased	0.370468859626566	14	330392	1295
Fluorescence-based primary biochemical high throughput screening assay to identify inhibitors of human diacylglycerol lipase, beta (DAGLB)	granulocyte count	DAGLB_inhibitors	targetBased	0.197624445455587	10	343468	202
HTS for Beta-2AR agonists via FAP method	granulocyte count	ADRB2_activators	targetBased	0.382445239658882	20	339297	1446
qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding	granulocyte count	MAPT	pathwayBased	0.178589586960066	11	267412	5703
qHTS Assay for Tau Filament Binding	granulocyte count	MAPT	targetBased	0.178589586960066	11	69668	1391
qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization	granulocyte count	MAPT	pathwayBased	0.178589586960066	11	271402	1048
Primary qHTS for Inhibitors of ATXN expression	granulocyte count	ATXN2_repressors	targetBased	0.195309413634631	21	358434	2554
Primary Cell-Based High-Throughput Screening to Identify Agonists of the Sphingosine 1-phosphate receptor 2 (S1P2)	granulocyte count	S1PR2	targetBased	0.231623920301967	9	96879	447
Primary Cell-Based High-Throughput Screening to Identify Antagonists of the Sphingosine 1-phosphate receptor 2 (S1P2)	granulocyte count	S1PR2	targetBased	0.231623920301967	9	96879	207
HTS for developing T Cell Immune Modulators	myeloid white cell count	ITGAL	targetBased	0.340657582404193	15	326271	221
Fluorescence-based primary biochemical high throughput screening assay to identify inhibitors of Protein Phosphatase 5 (PP5).	myeloid white cell count	PPP5C	targetBased	0.144341372665047	5	314999	564
HTS to identify compounds that promote myeloid differentiation with MLPCN compound set	myeloid white cell count	HOXA9	pathwayBased	0.222238691705537	5	358556	3721
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	myeloid white cell count	JAK2	targetBased	0.414883868508618	21	217959	2390
Identification of CBX7 inhibitors - Primary Alpha Screen	myeloid white cell count	Chromobox protein homolog 7 inhibitors	targetBased	0.360661190987611	8	64999	724
qHTS for Inhibitors of Polymerase Iota	myeloid white cell count	POLI	targetBased	0.218353093628445	15	386063	3989
qHTS Assay for Inhibitors of the CtBP/E1A Interaction	myeloid white cell count	RBBP8	targetBased	0.240971962545909	6	335214	1652
Primary cell-based high throughput screening assay to identify inhibitors of kruppel-like factor 5 (KLF5)	myeloid white cell count	KLF5	targetBased	0.325636334660595	4	290726	671
uHTS HTRF assay for identification of inhibitors of SUMOylation	myeloid white cell count	UBE2I	targetBased	0.223453561798624	7	290915	1039
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype	myeloid white cell count	RAB2A	targetBased	0.303141235162497	4	194628	365
Factor XIa 1536 HTS	blood protein measurement	F11_modulation	targetBased	0.555401607966835	76	218707	302
uHTS identification of modulators of interaction between CendR and NRP-1 using Fluorescence Polarization assay	blood protein measurement	NRP1	targetBased	0.493600092553911	7	363840	3086
qHTS for Inhibitors of TGF-b	blood protein measurement	TGFB1	pathwayBased	0.318226903871379	13	403345	4970
Small-molecule inhibitors of ST2 (IL1RL1)	blood protein measurement	IL1RL1	targetBased	0.512519522163457	23	75924	1804
uHTS identification of Caspase-8 TRAIL sensitizers in a luminesence assay	blood protein measurement	TNFRSF10B	targetBased	0.353397681777742	8	363840	3764
uHTS for the identification of compounds that potentiate TRAIL-induced apoptosis of cancer cells	blood protein measurement	TNFSF10	targetBased	0.40799437293213	7	217035	883
qHTS for Inhibitors of Cell Surface uPA Generation	blood protein measurement	PLAU	targetBased	0.465140620523197	7	325247	1021
Identification of Novel Modulators of Cl- dependent Transport Process via HTS: Primary Screen	blood protein measurement	SLC12A5	targetBased	0.169368745621088	5	189132	4127
uHTS identification of APOBEC3A DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay	blood protein measurement	APOBEC3A_inhibitors	targetBased	0.189122963542744	6	331753	1372
Factor XIIa 1536 HTS	blood protein measurement	F12_modulation	targetBased	0.257256543444349	67	217430	649
HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails	myeloid white cell count	HP1-betaChromodomainInteractionsInhibitors	targetBased	0.128847471034709	4	383363	2142
High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Primary Screen	myeloid white cell count	NFKB1	pathwayBased	0.42777082231263	17	193265	3100
uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay	myeloid white cell count	NFKB1	pathwayBased	0.42777082231263	17	359244	3094
Inhibitors of USP1/UAF1: Primary Screen	blood protein measurement	USP1	targetBased	0.183670609391733	6	389569	904
Luminescent assay for HTS discovery of chemical activators of placental alkaline phosphatase	blood protein measurement	ALPG_activators	targetBased	0.373949375145727	6	95729	1178
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb via a fluorescence resonance energy transfer (FRET) assay.	myeloid white cell count	RUNX1	targetBased	0.167095817493607	30	215667	993
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay.	myeloid white cell count	RUNX1	targetBased	0.167095817493607	30	218234	1620
qHTS Assay for Inhibitors of 15-hLO (15-human lipoxygenase)	myeloid white cell count	ALOX15_inhibitors	targetBased	0.274355720400272	28	73174	1034
Primary HTS assay for chemical inhibitors of TNF alpha stimulated VCAM1 expression	myeloid white cell count	VCAM1_expression	targetBased	0.394343990268558	9	94498	457
uHTS Luminescent assay for identification of inhibitors of NALP3 in yeast	myeloid white cell count	NLRP3	targetBased	0.47609407724236	22	330392	1295
Luminescence-based cell-based primary high throughput screening assay to identify biased ligands of the melanocortin 4 receptor (MC4R): agonists of MC4R	myeloid white cell count	MC4R	targetBased	0.141939975624121	4	356160	3470
TRFRET-based cell-based primary high throughput screening assay to identify biased ligands of the melanocortin 4 receptor (MC4R): antagonists of MC4R	myeloid white cell count	MC4R	targetBased	0.141939975624121	4	356160	1703
HTS for Beta-2AR agonists via FAP method	myeloid white cell count	ADRB2_activators	targetBased	0.453204063129725	25	339297	1446
Primary HTS and Confirmation Assays for S1P1 Agonists and Agonism Potentiators	myeloid white cell count	S1PR1	targetBased	0.42182085833492	20	55710	315
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	myeloid white cell count	FGB_inhibitors	targetBased	0.425525891254569	5	369953	760
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	myeloid white cell count	FGB_inhibitors	targetBased	0.425525891254569	5	369953	498
Absorbance-based biochemical primary high throughput screening assay to identify activators of Methionine sulfoxide reductase A (MsrA)	myeloid white cell count	MSRA	targetBased	0.192335900515786	6	362026	1074
Absorbance-based biochemical primary high throughput screening assay to identify inhibitors of Methionine sulfoxide reductase A (MsrA)	myeloid white cell count	MSRA	targetBased	0.192335900515786	6	362577	2709
MLPCN ERAP1 Measured in Biochemical System Using Plate Reader - 7016-01_Inhibitor_SinglePoint_HTS_Activity	blood protein measurement	ERAP1_inhibitors	targetBased	0.453619999467399	9	335777	499
Fluorescence-based primary biochemical high throughput screening assay to identify inhibitors of human diacylglycerol lipase, beta (DAGLB)	blood protein measurement	DAGLB_inhibitors	targetBased	0.404197956035884	5	343468	202
qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding	myeloid white cell count	MAPT	pathwayBased	0.204225669664004	12	267412	5703
qHTS Assay for Tau Filament Binding	myeloid white cell count	MAPT	targetBased	0.204225669664004	12	69668	1391
qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization	myeloid white cell count	MAPT	pathwayBased	0.204225669664004	12	271402	1048
Inhibitors of Cav3 T-type Calcium Channels: Primary Screen	myeloid white cell count	CACNA1H_inhibitors	targetBased	0.281852515878191	5	104728	4230
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of human platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (PAFAH1B2)	blood protein measurement	PAFAH1B2	targetBased	0.331541037239403	14	335239	4158
Alphascreen assay for small molecules abrogating mHTT-CaM Interaction	myeloid white cell count	HTT	targetBased	0.396219718678395	7	189882	6790
Primary qHTS for Identification of Small Molecule Inhibitors of Huntingtin Promoter Activity	myeloid white cell count	HTT	targetBased	0.396219718678395	7	48068	449
qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Aggregate Formation (GFP)	myeloid white cell count	HTT	targetBased	0.396219718678395	7	220571	2380
qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Cytoprotection (ATP)	myeloid white cell count	HTT	targetBased	0.396219718678395	7	223611	305
Fluorescence Intensity-based biochemical primary high throughput screening assay to identify activators of kallikrein-7 (K7) zymogen	blood protein measurement	KLK7	targetBased	0.40947793586846	13	368927	3325
Primary qHTS for Inhibitors of ATXN expression	myeloid white cell count	ATXN2_repressors	targetBased	0.192290405530971	25	358434	2554
Primary HTS Assay for S1P3 Antagonists	myeloid white cell count	S1PR3	targetBased	0.431111878591683	8	169141	462
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	blood protein measurement	FGB_inhibitors	targetBased	0.42272855644257	7	369953	760
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	blood protein measurement	FGB_inhibitors	targetBased	0.42272855644257	7	369953	498
Primary Cell-Based High-Throughput Screening to Identify Agonists of the Sphingosine 1-phosphate receptor 2 (S1P2)	myeloid white cell count	S1PR2	targetBased	0.407947334765787	12	96879	447
Primary Cell-Based High-Throughput Screening to Identify Antagonists of the Sphingosine 1-phosphate receptor 2 (S1P2)	myeloid white cell count	S1PR2	targetBased	0.407947334765787	12	96879	207
Thrombin 1536 HTS	blood protein measurement	F2_modulation	targetBased	0.408693708942221	11	217233	557
qHTS assay for re-activators of p53 using a Luc reporter	blood protein measurement	TP53	pathwayBased	0.203036806344934	4	321427	201
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Nonpermissive Temperature	blood protein measurement	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.203036806344934	4	54509	528
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Permissive Temperature	blood protein measurement	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.203036806344934	4	54513	338
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature	blood protein measurement	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.203036806344934	4	125394	1890
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Permissive Temperature	blood protein measurement	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.203036806344934	4	124022	1156
uHTS identification of small molecule inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase, LMPTP, via a fluorescence intensity assay	blood protein measurement	ACP1_inhibitors	targetBased	0.27960425022305	4	363840	817
Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression	blood protein measurement	SNCA	pathwayBased	0.500923769056078	6	140118	236
qHTS of alpha-syn Inhibitors	blood protein measurement	SNCA	pathwayBased	0.500923769056078	6	368791	501
Luminescence Cell-Based Primary HTS to Identify Inhibitors of A1 Apoptosis.	blood protein measurement	BCL2L11_inhibitors	targetBased	0.156938205863186	5	325630	216
HTS identification of compounds inhibiting the binding of CD11b/CD18 to fibrinogen via a luminescence assay.	blood protein measurement	ITGB2	targetBased	0.423816045964026	6	92518	501
S100A4: HTS Measured in Biochemical System Using Plate Reader - 7045-01_Inhibitor_SinglePoint_HTS_Activity	blood protein measurement	S100A4	targetBased	0.186968484765333	5	352235	501
Inhibitors of Cav3 T-type Calcium Channels: Primary Screen	blood protein measurement	CACNA1H_inhibitors	targetBased	0.259088156408848	6	104728	4230
qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a	blood protein measurement	EHMT2_inhibitors	targetBased	0.267315498254587	7	348338	30875
Primary qHTS for Inhibitors of ATXN expression	blood protein measurement	ATXN2_repressors	targetBased	0.220942187790452	16	358434	2554
Toxoplasma gondii inhibition HTS in the presence of IFN-y	myeloid white cell count	IFNG	targetBased	0.417022894284745	4	67275	2509
HTS for Identification of VLA-4 Allosteric Modulators from MLPCN library	myeloid white cell count	ITGA4	targetBased	0.513455010475936	27	326888	645
Antagonist identification of Pyk2 oligomerization: high-throughput screening cellular assay	myeloid white cell count	Pyk2Ã‚Â	targetBased	0.309064559123776	7	98749	818
qHTS Assay for Inhibitors of BAZ2B	myeloid white cell count	BAZ2B_modulators	targetBased	0.173313660183939	12	356826	15709
Primary Cell-Based Assay to Identify Agonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	myeloid white cell count	S1PR4	targetBased	0.470707832213289	32	217959	771
Primary Cell-Based Assay to Identify Antagonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	myeloid white cell count	S1PR4	targetBased	0.470707832213289	32	217959	569
uHTS identification of DNMT1 inhibitors in a Fluorescent Molecular Beacon assay	myeloid white cell count	DNMT1	targetBased	0.19362972364953	10	359244	2975
Primary cell-based high-throughput screening for identification of compounds that inhibit/block calcium-activated chloride channels (TMEM16A)	myeloid white cell count	ANO1_inhibitors	targetBased	0.150050941942907	7	306502	3633
Primary cell-based high-throughput screening for identification of compounds that activate/potentiate calcium-activated chloride channels (TMEM16A)	myeloid white cell count	ANO1_activators	targetBased	0.150050941942907	7	335180	1022
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	myeloid white cell count	PPARG	targetBased	0.38232839518734	19	99314	335
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	myeloid white cell count	PPARG	targetBased	0.38232839518734	19	196176	782
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	myeloid white cell count	PPARG	targetBased	0.38232839518734	19	99314	390
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	myeloid white cell count	PPARG	targetBased	0.38232839518734	19	196177	811
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	myeloid white cell count	PPARG	targetBased	0.38232839518734	19	196176	670
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	myeloid white cell count	PPARG	targetBased	0.38232839518734	19	196177	519
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of 5-meCpG-binding domain protein 2 (MBD2)-DBD binding to methylated oligonucleotide	myeloid white cell count	MBD2	targetBased	0.336762281251965	12	369953	1149
qHTS for Activators of Integrin-Mediated Alleviation for Muscular Dystrophy	myeloid white cell count	CGA_integrin_activators	targetBased	0.155722171843008	15	345855	222
QFRET-based biochemical primary high throughput screening assay to identify exosite inhibitors of ADAM10.	myeloid white cell count	ADAM10_inhibitors	targetBased	0.119377360250795	5	369953	2294
USP8 deubiquitinase inhibition: Primary qHTS	myeloid white cell count	USP8	targetBased	0.140957201473846	6	47480	2010
Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bfl-1	myeloid white cell count	BCL2A1_modulators	targetBased	0.470735292072277	22	194826	237
qHTS Assay for NPC1 Promoter Activators	myeloid white cell count	NPC1	pathwayBased	0.423491976770774	15	320682	7575
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of myeloid cell leukemia sequence 1 (MCL1) interactions with BIM-BH3 peptide.	myeloid white cell count	MCL1	targetBased	0.128622951103645	16	314998	2139
uHTS of Mcl-1/Bid interaction inhibitors	myeloid white cell count	MCL1	targetBased	0.128622951103645	16	218602	2129
uHTS of Mcl-1/Noxa interaction inhibitors	myeloid white cell count	MCL1	targetBased	0.128622951103645	16	217330	3334
qHTS Assay for Identifying a Potential Treatment of Ataxia-Telangiectasia	myeloid white cell count	ATM_modulators	targetBased	0.362737392644818	17	322361	619
Luminescence Cell-Based Primary HTS to Identify Inhibitors of A1 Apoptosis.	myeloid white cell count	BCL2L11_inhibitors	targetBased	0.209814480454269	29	325630	216
uHTS Fluorescent assay for identification of inhibitors of hexokinase domain containing I (HKDC1)	myeloid white cell count	HKDC1	targetBased	0.284485695535569	4	340696	540
Dyrk1 A HTS Measured in Biochemical System Using Plate Reader - 2124-01_Inhibitor_SinglePoint_HTS_Activity	myeloid white cell count	DYRK1A_inhibitors	targetBased	0.342112292049403	16	310014	1321
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	red blood cell density measurement	JAK2	targetBased	0.29304991748481	6	217959	2390
qHTS for Inhibitors of Polymerase Iota	red blood cell density measurement	POLI	targetBased	0.191687474180577	8	386063	3989
HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Inhibitor_SinglePoint_HTS_Activity	monocyte percentage of leukocytes	SCARB1	targetBased	0.431834411395037	5	319204	3065
HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Activator_SinglePoint_HTS_Activity	monocyte percentage of leukocytes	SCARB1	targetBased	0.431834411395037	5	316970	306
High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Primary Screen	monocyte percentage of leukocytes	NFKB1	pathwayBased	0.380492740191407	6	193265	3100
uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay	monocyte percentage of leukocytes	NFKB1	pathwayBased	0.380492740191407	6	359244	3094
HTS for Identification of VLA-4 Allosteric Modulators from MLPCN library	monocyte percentage of leukocytes	ITGA4	targetBased	0.500311638356786	12	326888	645
uHTS identification of Caspase-8 TRAIL sensitizers in a luminesence assay	monocyte percentage of leukocytes	TNFRSF10B	targetBased	0.310134601338484	6	363840	3764
uHTS for the identification of compounds that potentiate TRAIL-induced apoptosis of cancer cells	monocyte percentage of leukocytes	TNFSF10	targetBased	0.447580580862079	6	217035	883
qHTS Assay for Inhibitors of BAZ2B	monocyte percentage of leukocytes	BAZ2B_modulators	targetBased	0.366332215291218	5	356826	15709
Primary Cell-Based Assay to Identify Agonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	monocyte percentage of leukocytes	S1PR4	targetBased	0.423822535133245	8	217959	771
Primary Cell-Based Assay to Identify Antagonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	monocyte percentage of leukocytes	S1PR4	targetBased	0.423822535133245	8	217959	569
Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bfl-1	monocyte percentage of leukocytes	BCL2A1_modulators	targetBased	0.430959565611598	8	194826	237
Fluorescence-based primary biochemical high throughput screening assay to identify inhibitors of human diacylglycerol lipase, beta (DAGLB)	monocyte percentage of leukocytes	DAGLB_inhibitors	targetBased	0.434803643681786	5	343468	202
qHTS Assay for NPC1 Promoter Activators	monocyte percentage of leukocytes	NPC1	pathwayBased	0.40509314006181	11	320682	7575
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of myeloid cell leukemia sequence 1 (MCL1) interactions with BIM-BH3 peptide.	monocyte percentage of leukocytes	MCL1	targetBased	0.237529099095621	11	314998	2139
uHTS of Mcl-1/Bid interaction inhibitors	monocyte percentage of leukocytes	MCL1	targetBased	0.237529099095621	11	218602	2129
uHTS of Mcl-1/Noxa interaction inhibitors	monocyte percentage of leukocytes	MCL1	targetBased	0.237529099095621	11	217330	3334
Luminescence Cell-Based Primary HTS to Identify Inhibitors of A1 Apoptosis.	monocyte percentage of leukocytes	BCL2L11_inhibitors	targetBased	0.499905842324506	24	325630	216
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb via a fluorescence resonance energy transfer (FRET) assay.	monocyte percentage of leukocytes	RUNX1	targetBased	0.307215862228229	6	215667	993
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay.	monocyte percentage of leukocytes	RUNX1	targetBased	0.307215862228229	6	218234	1620
Primary HTS assay for chemical inhibitors of TNF alpha stimulated VCAM1 expression	monocyte percentage of leukocytes	VCAM1_expression	targetBased	0.215744694417904	5	94498	457
uHTS identification of HIF-2a Inhibitors in a luminesence assay	red blood cell density measurement	HIF-2a_inhibitors	targetBased	0.209822267961349	18	363840	2624
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	red blood cell density measurement	PPARG	targetBased	0.414869431694671	5	99314	335
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	red blood cell density measurement	PPARG	targetBased	0.414869431694671	5	196176	782
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	red blood cell density measurement	PPARG	targetBased	0.414869431694671	5	99314	390
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	red blood cell density measurement	PPARG	targetBased	0.414869431694671	5	196177	811
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	red blood cell density measurement	PPARG	targetBased	0.414869431694671	5	196176	670
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	red blood cell density measurement	PPARG	targetBased	0.414869431694671	5	196177	519
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of 5-meCpG-binding domain protein 2 (MBD2)-DBD binding to methylated oligonucleotide	red blood cell density measurement	MBD2	targetBased	0.208417795180601	8	369953	1149
HTS for Estrogen Receptor-beta Coactivator Binding inhibitors	red blood cell density measurement	ESR2_inhibitors	targetBased	0.480867467058156	5	86095	1114
Primary Cell-based High Throughput Screening assay for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA)	balding measurement	RORA	pathwayBased	0.374419466043923	6	64908	979
Primary Cell-based High Throughput Screening assay for inhibitors of the Retinoic Acid Receptor-related orphan receptor A (RORA)	balding measurement	RORA	pathwayBased	0.374419466043923	6	64908	278
Fluorescence-based biochemical high throughput primary assay to identify inhibitors of phospholipase C isozymes (PLC-beta3).	red blood cell density measurement	PLCB3	targetBased	0.318870760947023	5	369953	662
Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2	red blood cell density measurement	THRB	targetBased	0.458490879112183	5	276265	806
Luminescence Cell-Based Primary HTS to Identify Inhibitors of A1 Apoptosis.	red blood cell density measurement	BCL2L11_inhibitors	targetBased	0.478623297831101	17	325630	216
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb via a fluorescence resonance energy transfer (FRET) assay.	red blood cell density measurement	RUNX1	targetBased	0.268708332228818	6	215667	993
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay.	red blood cell density measurement	RUNX1	targetBased	0.268708332228818	6	218234	1620
HTS for Beta-2AR agonists via FAP method	monocyte percentage of leukocytes	ADRB2_activators	targetBased	0.397105106917609	5	339297	1446
Primary biochemical high throughput screening assay to identify inhibitors of BCL2-related protein, long isoform (BCLXL).	monocyte percentage of leukocytes	BCL2L1_modulators	targetBased	0.157260602402543	5	314998	2199
Primary HTS Assay for S1P3 Antagonists	monocyte percentage of leukocytes	S1PR3	targetBased	0.534418257486305	9	169141	462
HTS for developing T Cell Immune Modulators	neutrophil percentage of leukocytes	ITGAL	targetBased	0.281784872344502	5	326271	221
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	neutrophil percentage of leukocytes	JAK2	targetBased	0.288864232600226	5	217959	2390
Nrf2 qHTS screen for inhibitors	balding measurement	nrf2Inhibitors	targetBased	0.124451982942166	6	360873	7438
qHTS of Nrf2 Activators	balding measurement	Nrf2 activators	pathwayBased	0.124451982942166	6	403871	1243
Fluorescence-based biochemical high throughput primary assay to identify inhibitors of phospholipase C isozymes (PLC-gamma1).	balding measurement	PLCG1	targetBased	0.160513178822174	5	369953	3123
High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Primary Screen	neutrophil percentage of leukocytes	NFKB1	pathwayBased	0.309230250141393	5	193265	3100
uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay	neutrophil percentage of leukocytes	NFKB1	pathwayBased	0.309230250141393	5	359244	3094
HTS for Identification of VLA-4 Allosteric Modulators from MLPCN library	neutrophil percentage of leukocytes	ITGA4	targetBased	0.421460582910698	9	326888	645
Small-molecule inhibitors of ST2 (IL1RL1)	neutrophil percentage of leukocytes	IL1RL1	targetBased	0.379730569205608	5	75924	1804
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb via a fluorescence resonance energy transfer (FRET) assay.	balding measurement	RUNX1	targetBased	0.237489113709782	6	215667	993
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay.	balding measurement	RUNX1	targetBased	0.237489113709782	6	218234	1620
qHTS Assay for Inhibitors of BAZ2B	neutrophil percentage of leukocytes	BAZ2B_modulators	targetBased	0.363567744215653	6	356826	15709
Primary Cell-Based Assay to Identify Agonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	neutrophil percentage of leukocytes	S1PR4	targetBased	0.424616236713182	12	217959	771
Primary Cell-Based Assay to Identify Antagonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	neutrophil percentage of leukocytes	S1PR4	targetBased	0.424616236713182	12	217959	569
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	neutrophil percentage of leukocytes	PPARG	targetBased	0.368393972310217	5	99314	335
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	neutrophil percentage of leukocytes	PPARG	targetBased	0.368393972310217	5	196176	782
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	neutrophil percentage of leukocytes	PPARG	targetBased	0.368393972310217	5	99314	390
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	neutrophil percentage of leukocytes	PPARG	targetBased	0.368393972310217	5	196177	811
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	neutrophil percentage of leukocytes	PPARG	targetBased	0.368393972310217	5	196176	670
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	neutrophil percentage of leukocytes	PPARG	targetBased	0.368393972310217	5	196177	519
qHTS Assay for NPC1 Promoter Activators	neutrophil percentage of leukocytes	NPC1	pathwayBased	0.40086331634606	9	320682	7575
Primary HTS assay for chemical inhibitors of TNF alpha stimulated VCAM1 expression	neutrophil percentage of leukocytes	VCAM1_expression	targetBased	0.160222253979685	8	94498	457
uHTS Luminescent assay for identification of inhibitors of NALP3 in yeast	neutrophil percentage of leukocytes	NLRP3	targetBased	0.395698536607623	8	330392	1295
Fluorescence-based primary biochemical high throughput screening assay to identify inhibitors of human diacylglycerol lipase, beta (DAGLB)	neutrophil percentage of leukocytes	DAGLB_inhibitors	targetBased	0.432953640509353	6	343468	202
HTS for Beta-2AR agonists via FAP method	neutrophil percentage of leukocytes	ADRB2_activators	targetBased	0.40806365188716	5	339297	1446
Primary HTS and Confirmation Assays for S1P1 Agonists and Agonism Potentiators	neutrophil percentage of leukocytes	S1PR1	targetBased	0.49065160042818	14	55710	315
qHTS screen for small molecules that induce genotoxicity in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1	neutrophil percentage of leukocytes	ATAD5_inhibitors	targetBased	0.231841453719236	5	330109	4174
qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1	neutrophil percentage of leukocytes	ATAD5_inhibitors	targetBased	0.231841453719236	5	330107	7652
Primary qHTS for Inhibitors of ATXN expression	neutrophil percentage of leukocytes	ATXN2_repressors	targetBased	0.322492867161035	5	358434	2554
Primary HTS Assay for S1P3 Antagonists	neutrophil percentage of leukocytes	S1PR3	targetBased	0.316614582142193	5	169141	462
Primary Cell-based High Throughput Screening assay for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA)	eosinophil percentage of leukocytes	RORA	pathwayBased	0.374173315086675	5	64908	979
Primary Cell-based High Throughput Screening assay for inhibitors of the Retinoic Acid Receptor-related orphan receptor A (RORA)	eosinophil percentage of leukocytes	RORA	pathwayBased	0.374173315086675	5	64908	278
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	eosinophil percentage of leukocytes	JAK2	targetBased	0.35677628523487	14	217959	2390
ROC1-CUL1 CTD Inhibitor di-Ub FRET Primary HTS Screen	eosinophil percentage of leukocytes	RBX1	targetBased	0.189409326138702	5	143816	859
qHTS Assay for Inhibitors of the CtBP/E1A Interaction	eosinophil percentage of leukocytes	RBBP8	targetBased	0.324451961876228	5	335214	1652
Luminescence-based primary cell-based high throughput screening assay to identify activators of the Aryl Hydrocarbon Receptor (AHR)	eosinophil percentage of leukocytes	AHR_activators	targetBased	0.404619797616114	5	324747	7988
High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Primary Screen	eosinophil percentage of leukocytes	NFKB1	pathwayBased	0.448536617495554	6	193265	3100
uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay	eosinophil percentage of leukocytes	NFKB1	pathwayBased	0.448536617495554	6	359244	3094
qHTS of IL-2 Activators	eosinophil percentage of leukocytes	IL2	targetBased	0.173671246819433	5	364617	238
Small-molecule inhibitors of ST2 (IL1RL1)	eosinophil percentage of leukocytes	IL1RL1	targetBased	0.42400044645187	12	75924	1804
Primary Cell-Based Assay to Identify Agonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	eosinophil percentage of leukocytes	S1PR4	targetBased	0.57119427655971	11	217959	771
Primary Cell-Based Assay to Identify Antagonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	eosinophil percentage of leukocytes	S1PR4	targetBased	0.57119427655971	11	217959	569
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	eosinophil percentage of leukocytes	PPARG	targetBased	0.484736040400107	9	99314	335
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	eosinophil percentage of leukocytes	PPARG	targetBased	0.484736040400107	9	196176	782
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	eosinophil percentage of leukocytes	PPARG	targetBased	0.484736040400107	9	99314	390
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	eosinophil percentage of leukocytes	PPARG	targetBased	0.484736040400107	9	196177	811
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	eosinophil percentage of leukocytes	PPARG	targetBased	0.484736040400107	9	196176	670
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	eosinophil percentage of leukocytes	PPARG	targetBased	0.484736040400107	9	196177	519
uHTS Luminescent assay for identification of inhibitors of Sentrin-specific protease 7 (SENP7)	eosinophil percentage of leukocytes	SENP7	targetBased	0.324468481031365	5	331670	4902
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of myeloid cell leukemia sequence 1 (MCL1) interactions with BIM-BH3 peptide.	eosinophil percentage of leukocytes	MCL1	targetBased	0.168868339250173	8	314998	2139
uHTS of Mcl-1/Bid interaction inhibitors	eosinophil percentage of leukocytes	MCL1	targetBased	0.168868339250173	8	218602	2129
uHTS of Mcl-1/Noxa interaction inhibitors	eosinophil percentage of leukocytes	MCL1	targetBased	0.168868339250173	8	217330	3334
qHTS Assay for Identifying a Potential Treatment of Ataxia-Telangiectasia	eosinophil percentage of leukocytes	ATM_modulators	targetBased	0.267573595388993	5	322361	619
Luminescence Cell-Based Primary HTS to Identify Inhibitors of A1 Apoptosis.	eosinophil percentage of leukocytes	BCL2L11_inhibitors	targetBased	0.424163628986218	11	325630	216
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb via a fluorescence resonance energy transfer (FRET) assay.	eosinophil percentage of leukocytes	RUNX1	targetBased	0.282427965780755	20	215667	993
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay.	eosinophil percentage of leukocytes	RUNX1	targetBased	0.282427965780755	20	218234	1620
qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS	platelet component distribution width	GNAS	targetBased	0.353959753600252	9	334825	423
qHTS for Antagonists of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS	platelet component distribution width	GNAS	targetBased	0.353959753600252	9	337446	1356
HTS for Identification of VLA-4 Allosteric Modulators from MLPCN library	neutrophil-to-lymphocyte ratio	ITGA4	targetBased	0.415022410184308	5	326888	645
qHTS Assay for Inhibitors of 15-hLO (15-human lipoxygenase)	eosinophil percentage of leukocytes	ALOX15_inhibitors	targetBased	0.706952569843882	27	73174	1034
HTS of Smad transcription factor inhibitors	eosinophil percentage of leukocytes	SMAD3	targetBased	0.5357359281835	15	88033	251
HTS for Beta-2AR agonists via FAP method	eosinophil percentage of leukocytes	ADRB2_activators	targetBased	0.494501963361436	8	339297	1446
uHTS identification of small molecule antagonists of the EBI2 receptor via a luminescent beta-arrestin assay	eosinophil percentage of leukocytes	GPR183	targetBased	0.170904905793816	6	363840	2946
Primary HTS and Confirmation Assays for S1P1 Agonists and Agonism Potentiators	eosinophil percentage of leukocytes	S1PR1	targetBased	0.451202977659147	9	55710	315
Primary biochemical high throughput screening assay to identify inhibitors of BCL2-related protein, long isoform (BCLXL).	eosinophil percentage of leukocytes	BCL2L1_modulators	targetBased	0.360241586731447	5	314998	2199
qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding	eosinophil percentage of leukocytes	MAPT	pathwayBased	0.13434270978835	6	267412	5703
qHTS Assay for Tau Filament Binding	eosinophil percentage of leukocytes	MAPT	targetBased	0.13434270978835	6	69668	1391
qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization	eosinophil percentage of leukocytes	MAPT	pathwayBased	0.13434270978835	6	271402	1048
Primary qHTS for Inhibitors of ATXN expression	eosinophil percentage of leukocytes	ATXN2_repressors	targetBased	0.299903344456949	6	358434	2554
Primary Cell-Based Assay to Identify Agonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	basophil percentage of leukocytes	S1PR4	targetBased	0.577947261613922	5	217959	771
Primary Cell-Based Assay to Identify Antagonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	basophil percentage of leukocytes	S1PR4	targetBased	0.577947261613922	5	217959	569
qHTS Assay for NPC1 Promoter Activators	platelet component distribution width	NPC1	pathwayBased	0.438780883933169	18	320682	7575
qHTS for Inhibitors of phosphatidylinositol 5-phosphate 4-kinase (PI5P4K)	platelet component distribution width	PIP4K2A	targetBased	0.126968955386687	5	328860	4078
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors of ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 (ASAP1)	platelet component distribution width	ASAP1_inhibitors	targetBased	0.41431583522813	5	362577	680
Inhibitors of USP1/UAF1: Primary Screen	platelet component distribution width	USP1	targetBased	0.180711390052525	5	389569	904
Primary Cell-based High Throughput Screening Assay for Inhibitors of Wee1 Degradation	platelet component distribution width	WEE1	targetBased	0.39076374331581	8	217959	2616
HTS for Beta-2AR agonists via FAP method	platelet component distribution width	ADRB2_activators	targetBased	0.117422174476362	5	339297	1446
Primary cell-based high-throughput screening assay for identification of compounds that inhibit KCNQ1 potassium channels	platelet crit	KCNQ1	targetBased	0.371576197872454	12	305610	3878
Primary cell-based high-throughput screening assay for identification of compounds that potentiate/activate KCNQ1 potassium channels	platelet crit	KCNQ1	targetBased	0.371576197872454	12	305610	1082
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	platelet crit	JAK2	targetBased	0.768707774378392	50	217959	2390
Toxoplasma gondii inhibition HTS in the presence of IFN-y	platelet crit	IFNG	targetBased	0.373641669983215	21	67275	2509
uHTS for the identification of compounds that potentiate TRAIL-induced apoptosis of cancer cells	platelet crit	TNFSF10	targetBased	0.39141356399193	6	217035	883
qHTS Assay for Inhibitors of BAZ2B	platelet crit	BAZ2B_modulators	targetBased	0.34300300432673	9	356826	15709
Primary Cell-Based Assay to Identify Agonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	platelet crit	S1PR4	targetBased	0.454071924575338	6	217959	771
Primary Cell-Based Assay to Identify Antagonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	platelet crit	S1PR4	targetBased	0.454071924575338	6	217959	569
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	platelet crit	PPARG	targetBased	0.425536410978553	8	99314	335
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	platelet crit	PPARG	targetBased	0.425536410978553	8	196176	782
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	platelet crit	PPARG	targetBased	0.425536410978553	8	99314	390
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	platelet crit	PPARG	targetBased	0.425536410978553	8	196177	811
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	platelet crit	PPARG	targetBased	0.425536410978553	8	196176	670
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	platelet crit	PPARG	targetBased	0.425536410978553	8	196177	519
Luminescence Cell-Based Primary HTS to Identify Inhibitors of A1 Apoptosis.	lymphocyte percentage of leukocytes	BCL2L11_inhibitors	targetBased	0.365701269096281	9	325630	216
Primary HTS assay for chemical inhibitors of TNF alpha stimulated VCAM1 expression	lymphocyte percentage of leukocytes	VCAM1_expression	targetBased	0.275029602196039	5	94498	457
uHTS Luminescent assay for identification of inhibitors of NALP3 in yeast	lymphocyte percentage of leukocytes	NLRP3	targetBased	0.31957250886957	5	330392	1295
Fluorescence-based primary biochemical high throughput screening assay to identify inhibitors of human diacylglycerol lipase, beta (DAGLB)	lymphocyte percentage of leukocytes	DAGLB_inhibitors	targetBased	0.405488675052795	8	343468	202
HTS for Beta-2AR agonists via FAP method	lymphocyte percentage of leukocytes	ADRB2_activators	targetBased	0.400600115359476	5	339297	1446
Primary HTS and Confirmation Assays for S1P1 Agonists and Agonism Potentiators	lymphocyte percentage of leukocytes	S1PR1	targetBased	0.512208341739393	15	55710	315
Primary qHTS for Inhibitors of ATXN expression	lymphocyte percentage of leukocytes	ATXN2_repressors	targetBased	0.302406341040936	5	358434	2554
Absorbance-based biochemical primary high throughput screening assay to identify activators of Methionine sulfoxide reductase A (MsrA)	platelet component distribution width	MSRA	targetBased	0.203620000773484	8	362026	1074
Absorbance-based biochemical primary high throughput screening assay to identify inhibitors of Methionine sulfoxide reductase A (MsrA)	platelet component distribution width	MSRA	targetBased	0.203620000773484	8	362577	2709
Primary HTS Assay for S1P3 Antagonists	lymphocyte percentage of leukocytes	S1PR3	targetBased	0.350359016811302	5	169141	462
HTS for developing T Cell Immune Modulators	lymphocyte percentage of leukocytes	ITGAL	targetBased	0.284476584622016	5	326271	221
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	lymphocyte percentage of leukocytes	JAK2	targetBased	0.524444660668715	9	217959	2390
High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Primary Screen	lymphocyte percentage of leukocytes	NFKB1	pathwayBased	0.193990607526064	5	193265	3100
uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay	lymphocyte percentage of leukocytes	NFKB1	pathwayBased	0.193990607526064	5	359244	3094
Primary qHTS for Inhibitors of ATXN expression	platelet component distribution width	ATXN2_repressors	targetBased	0.157841069454943	5	358434	2554
HTS for Identification of VLA-4 Allosteric Modulators from MLPCN library	lymphocyte percentage of leukocytes	ITGA4	targetBased	0.490984327154495	14	326888	645
Primary Cell-Based Assay to Identify Agonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	lymphocyte percentage of leukocytes	S1PR4	targetBased	0.370183002081494	6	217959	771
Primary Cell-Based Assay to Identify Antagonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	lymphocyte percentage of leukocytes	S1PR4	targetBased	0.370183002081494	6	217959	569
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	lymphocyte percentage of leukocytes	PPARG	targetBased	0.330277991145737	5	99314	335
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	lymphocyte percentage of leukocytes	PPARG	targetBased	0.330277991145737	5	196176	782
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	lymphocyte percentage of leukocytes	PPARG	targetBased	0.330277991145737	5	99314	390
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	lymphocyte percentage of leukocytes	PPARG	targetBased	0.330277991145737	5	196177	811
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	lymphocyte percentage of leukocytes	PPARG	targetBased	0.330277991145737	5	196176	670
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	lymphocyte percentage of leukocytes	PPARG	targetBased	0.330277991145737	5	196177	519
qHTS Assay for Identifying a Potential Treatment of Ataxia-Telangiectasia	platelet crit	ATM_modulators	targetBased	0.25764574598176	8	322361	619
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb via a fluorescence resonance energy transfer (FRET) assay.	platelet crit	RUNX1	targetBased	0.457057641620109	21	215667	993
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay.	platelet crit	RUNX1	targetBased	0.457057641620109	21	218234	1620
Primary HTS assay for chemical inhibitors of TNF alpha stimulated VCAM1 expression	platelet crit	VCAM1_expression	targetBased	0.125764517814589	5	94498	457
uHTS Luminescent assay for identification of inhibitors of NALP3 in yeast	platelet crit	NLRP3	targetBased	0.346663679053195	9	330392	1295
qHTS Assay for Activators of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease	platelet crit	GAA	targetBased	0.305685649650671	5	199169	715
qHTS Assay for Inhibitors and Activators of Human alpha-Glucosidase Cleavage of Glycogen	platelet crit	GAA_inhibitors	targetBased	0.305685649650671	5	302297	1165
Primary biochemical high throughput screening assay to identify inhibitors of BCL2-related protein, long isoform (BCLXL).	platelet crit	BCL2L1_modulators	targetBased	0.465197918028226	21	314998	2199
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb via a fluorescence resonance energy transfer (FRET) assay.	eosinophil percentage of granulocytes	RUNX1	targetBased	0.202788589566499	5	215667	993
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay.	eosinophil percentage of granulocytes	RUNX1	targetBased	0.202788589566499	5	218234	1620
Luminescence Cell-Based Primary HTS to Identify Inhibitors of A1 Apoptosis.	granulocyte percentage of myeloid white cells	BCL2L11_inhibitors	targetBased	0.36447964809066	8	325630	216
Primary qHTS for Inhibitors of ATXN expression	platelet crit	ATXN2_repressors	targetBased	0.303261525099176	27	358434	2554
Primary HTS Assay for S1P3 Antagonists	platelet crit	S1PR3	targetBased	0.284984455547675	8	169141	462
High Content Assay for Compounds that inhibit the Assembly of the Perinucleolar Compartment	reticulocyte count	PTBP1	targetBased	0.357132233723536	6	139718	4338
uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (PABP)	reticulocyte count	PABPC1	targetBased	0.259312584959967	6	290915	2982
uHTS identification of microRNA-mediated mRNA deadenylation inhibitors by fluoresence polarization assay	reticulocyte count	PABPC1	targetBased	0.259312584959967	6	359244	1307
uHTS identification of small molecule inhibitors of the catalytic domain of the SUMO protease, SENP1 in a FRET assay	reticulocyte count	SENP1	targetBased	0.234964090830633	6	363840	774
HTS for Tumor Hsp90 Inhibitors	reticulocyte count	HSP90 known inhibitor displacement	targetBased	0.297856609981261	6	63696	220
Luminescence-based primary biochemical high throughput screening assay to identify inhibitors of the Heat Shock Protein 90 (HSP90)	reticulocyte count	HSP90AA1	targetBased	0.297856609981261	6	290726	2649
HTS Assay for Peg3 Promoter Inhibitors	reticulocyte count	PPP1R15A	targetBased	0.433814758731472	30	359244	6145
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	reticulocyte count	JAK2	targetBased	0.433064037215451	8	217959	2390
USP10 deubiquitinase inhibition: Primary qHTS	reticulocyte count	USP10	targetBased	0.41770124886614	18	47480	509
uHTS luminescence assay for the identification of compounds that inhibit NOD1	reticulocyte count	NOD1	targetBased	0.472943994248901	9	289422	2997
High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Primary Screen	reticulocyte count	NFKB1	pathwayBased	0.414094763667537	8	193265	3100
uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay	reticulocyte count	NFKB1	pathwayBased	0.414094763667537	8	359244	3094
HTS for Identification of VLA-4 Allosteric Modulators from MLPCN library	reticulocyte count	ITGA4	targetBased	0.518931501685393	11	326888	645
qHTS for Inhibitors of Glutaminase (GLS)	reticulocyte count	GLS	targetBased	0.47446702034779	14	405291	844
Flow Cytometric HTS Screen for inhibitors of the ABC transporter ABCB6 for MLPCN Compound Set	reticulocyte count	ABCB6_inhibitors	targetBased	0.672855333065367	30	362098	692
uHTS identification of HIF-2a Inhibitors in a luminesence assay	reticulocyte count	HIF-2a_inhibitors	targetBased	0.131062770913988	9	363840	2624
Fluorescence-based biochemical high throughput primary assay to identify inhibitors of phospholipase C isozymes (PLC-gamma1).	reticulocyte count	PLCG1	targetBased	0.321062284476218	5	369953	3123
uHTS identification of DNMT1 inhibitors in a Fluorescent Molecular Beacon assay	reticulocyte count	DNMT1	targetBased	0.226056688173626	29	359244	2975
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	reticulocyte count	PPARG	targetBased	0.407339533721477	14	99314	335
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	reticulocyte count	PPARG	targetBased	0.407339533721477	14	196176	782
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	reticulocyte count	PPARG	targetBased	0.407339533721477	14	99314	390
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	reticulocyte count	PPARG	targetBased	0.407339533721477	14	196177	811
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	reticulocyte count	PPARG	targetBased	0.407339533721477	14	196176	670
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	reticulocyte count	PPARG	targetBased	0.407339533721477	14	196177	519
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac activated mutant	reticulocyte count	RAC1	targetBased	0.205537776608727	5	194629	219
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac wildtype	reticulocyte count	RAC1	targetBased	0.205537776608727	5	194628	521
Luminescence cell-based high throughput primary assay to identify inhibitors of TEAD-YAP interaction.	reticulocyte count	YAP1	targetBased	0.420633481225064	6	639428	9218
qHTS Assay for NPC1 Promoter Activators	reticulocyte count	NPC1	pathwayBased	0.169885340350302	8	320682	7575
Fluorescence-based biochemical high throughput primary assay to identify inhibitors of phospholipase C isozymes (PLC-beta3).	reticulocyte count	PLCB3	targetBased	0.198885095183988	12	369953	662
uHTS Fluorescent assay for identification of inhibitors of hexokinase domain containing I (HKDC1)	reticulocyte count	HKDC1	targetBased	0.347973683337417	18	340696	540
Fluorescence-based primary biochemical high throughput screening assay to identify inhibitors of human diacylglycerol lipase, beta (DAGLB)	reticulocyte count	DAGLB_inhibitors	targetBased	0.344183834240912	8	343468	202
uHTS for 14-3-3/Bad interaction inhibitors	reticulocyte count	YWHAZ	targetBased	0.479856810825538	12	217332	1549
qHTS Assay for Activators of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease	reticulocyte count	GAA	targetBased	0.437507575811623	21	199169	715
qHTS Assay for Inhibitors and Activators of Human alpha-Glucosidase Cleavage of Glycogen	reticulocyte count	GAA_inhibitors	targetBased	0.437507575811623	21	302297	1165
qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding	reticulocyte count	MAPT	pathwayBased	0.233454212070012	14	267412	5703
qHTS Assay for Tau Filament Binding	reticulocyte count	MAPT	targetBased	0.233454212070012	14	69668	1391
qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization	reticulocyte count	MAPT	pathwayBased	0.233454212070012	14	271402	1048
Primary qHTS for Inhibitors of ATXN expression	reticulocyte count	ATXN2_repressors	targetBased	0.396416457369395	27	358434	2554
Primary HTS Assay for S1P3 Antagonists	reticulocyte count	S1PR3	targetBased	0.437424027965407	20	169141	462
Primary Cell-Based High-Throughput Screening to Identify Agonists of the Sphingosine 1-phosphate receptor 2 (S1P2)	reticulocyte count	S1PR2	targetBased	0.603933460546532	39	96879	447
Primary Cell-Based High-Throughput Screening to Identify Antagonists of the Sphingosine 1-phosphate receptor 2 (S1P2)	reticulocyte count	S1PR2	targetBased	0.603933460546532	39	96879	207
Luminescence Cell-Based Primary HTS to Identify Inhibitors of A1 Apoptosis.	platelet crit	BCL2L11_inhibitors	targetBased	0.283032521077649	12	325630	216
Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2	reticulocyte count	THRB	targetBased	0.520785206171264	20	276265	806
Luminescence Cell-Based Primary HTS to Identify Inhibitors of A1 Apoptosis.	reticulocyte count	BCL2L11_inhibitors	targetBased	0.510475068680431	24	325630	216
Luminescence Cell-Based Primary HTS to Identify Inhibitors of A1 Apoptosis.	neutrophil percentage of leukocytes	BCL2L11_inhibitors	targetBased	0.436618510572201	14	325630	216
Small-molecule inhibitors of ST2 (IL1RL1)	sum of eosinophil and basophil counts	IL1RL1	targetBased	0.400177736389708	5	75924	1804
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb via a fluorescence resonance energy transfer (FRET) assay.	sum of eosinophil and basophil counts	RUNX1	targetBased	0.204671730566904	5	215667	993
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay.	sum of eosinophil and basophil counts	RUNX1	targetBased	0.204671730566904	5	218234	1620
qHTS for Inhibitors of Inflammasome Signaling: IL-1-beta AlphaLISA Primary Screen	Corpuscular Hemoglobin Content	IL-1b Inflammasome	pathwayBased	0.114016954191093	90	362051	17187
Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign	Corpuscular Hemoglobin Content	TSHR	targetBased	0.105752402880205	138	329153	670
Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign	Corpuscular Hemoglobin Content	TSHR	targetBased	0.105752402880205	138	329153	670
qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor	Corpuscular Hemoglobin Content	TSHR	targetBased	0.105752402880205	138	72026	352
qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor: Activators of Intracellular cAMP Concentrations in Parental HEK 293	Corpuscular Hemoglobin Content	TSHR	targetBased	0.105752402880205	138	72026	1794
HTS Assay for Peg3 Promoter Inhibitors	Immature Reticulocyte Fraction Measurement	PPP1R15A	targetBased	0.296103445890004	5	359244	6145
HTS for Identification of VLA-4 Allosteric Modulators from MLPCN library	Immature Reticulocyte Fraction Measurement	ITGA4	targetBased	0.477288261470931	6	326888	645
Flow Cytometric HTS Screen for inhibitors of the ABC transporter ABCB6 for MLPCN Compound Set	Immature Reticulocyte Fraction Measurement	ABCB6_inhibitors	targetBased	0.227538908285503	5	362098	692
uHTS identification of DNMT1 inhibitors in a Fluorescent Molecular Beacon assay	Immature Reticulocyte Fraction Measurement	DNMT1	targetBased	0.187549550271498	6	359244	2975
Luminescence Cell-Based Primary HTS to Identify Inhibitors of A1 Apoptosis.	Immature Reticulocyte Fraction Measurement	BCL2L11_inhibitors	targetBased	0.386117968656606	9	325630	216
uHTS for 14-3-3/Bad interaction inhibitors	Immature Reticulocyte Fraction Measurement	YWHAZ	targetBased	0.400079866188981	5	217332	1549
Primary Cell-Based High-Throughput Screening to Identify Agonists of the Sphingosine 1-phosphate receptor 2 (S1P2)	Immature Reticulocyte Fraction Measurement	S1PR2	targetBased	0.414998088574612	9	96879	447
Primary Cell-Based High-Throughput Screening to Identify Antagonists of the Sphingosine 1-phosphate receptor 2 (S1P2)	Immature Reticulocyte Fraction Measurement	S1PR2	targetBased	0.414998088574612	9	96879	207
Factor XIa 1536 HTS	blood coagulation disease	F11_modulation	targetBased	0.405057393873445	254	218707	302
HTS of Estrogen Receptor- alpha Coactivator Binding inhibitors	blood coagulation disease	ESR1_inhibitors	targetBased	0.190059787713429	16	86095	1442
HTS of Estrogen Receptor- alpha Coactivator Binding Potentiators	blood coagulation disease	ESR1_modulators	targetBased	0.190059787713429	16	86095	1151
Inhibitors of the vitamin D receptor (VDR): qHTS	blood coagulation disease	VDR	targetBased	0.199157521816973	6	394050	3624
Factor XIIa 1536 HTS	blood coagulation disease	F12_modulation	targetBased	0.300346628526255	44	217430	649
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	blood coagulation disease	FGB_inhibitors	targetBased	0.57927882376402	97	369953	760
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	blood coagulation disease	FGB_inhibitors	targetBased	0.57927882376402	97	369953	498
Thrombin 1536 HTS	blood coagulation disease	F2_modulation	targetBased	0.338759163395046	1156	217233	557
HTS of Estrogen Receptor- alpha Coactivator Binding inhibitors	thrombophilia	ESR1_inhibitors	targetBased	0.507615061227162	11	86095	1442
HTS of Estrogen Receptor- alpha Coactivator Binding Potentiators	thrombophilia	ESR1_modulators	targetBased	0.507615061227162	11	86095	1151
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	thrombophilia	FGB_inhibitors	targetBased	0.407166483204466	9	369953	760
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	thrombophilia	FGB_inhibitors	targetBased	0.407166483204466	9	369953	498
Thrombin 1536 HTS	thrombophilia	F2_modulation	targetBased	0.293465503482633	718	217233	557
qHTS for Inhibitors of TGF-b	immature platelet fraction	TGFB1	pathwayBased	0.123443682404158	1559	403345	4970
uHTS for the identification of compounds that potentiate TRAIL-induced apoptosis of cancer cells	immature platelet fraction	TNFSF10	targetBased	0.100555808588668	18	217035	883
HTS Assay for Inhibitors of Akt Phophorylation: Primary Screen	immature platelet fraction	AKT1_inhibitors	targetBased	0.116529857829124	189	356517	1139
Acumen qHTS Assay for Inhibitors of the mTORC1 Signaling Pathway in MEF (Tsc2-/-, p53-/-) Cells: Sytravon	immature platelet fraction	MTOR	pathwayBased	0.10340449728277	116	43989	342
HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Inhibitor_SinglePoint_HTS_Activity	Red cell distribution width	SCARB1	targetBased	0.508248795307349	14	319204	3065
HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Activator_SinglePoint_HTS_Activity	Red cell distribution width	SCARB1	targetBased	0.508248795307349	14	316970	306
HTS for Tumor Hsp90 Inhibitors	Red cell distribution width	HSP90 known inhibitor displacement	targetBased	0.226912517554113	9	63696	220
Luminescence-based primary biochemical high throughput screening assay to identify inhibitors of the Heat Shock Protein 90 (HSP90)	Red cell distribution width	HSP90AA1	targetBased	0.226912517554113	9	290726	2649
HTS Assay for Peg3 Promoter Inhibitors	Red cell distribution width	PPP1R15A	targetBased	0.443771922703151	17	359244	6145
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of the interaction of the Ras and Rab interactor 1 protein (Rin1) and the c-abl oncogene 1, non-receptor tyrosine kinase (Abl)	Red cell distribution width	ABL1_interaction	targetBased	0.378969582174646	8	359207	1432
Identification of Molecular Probes that Activate MRP-1	Red cell distribution width	ABCC1_activators	targetBased	0.479187869730178	6	138717	842
EZH2/PRC2 methyltransferase inhibitors Measured in Biochemical System Using Plate Reader - 2125-01_Inhibitor_SinglePoint_HTS_Activity	Red cell distribution width	EZH2_inhibitors	targetBased	0.371494700162111	6	57013	201
Flow Cytometric HTS Screen for inhibitors of the ABC transporter ABCB6 for MLPCN Compound Set	Red cell distribution width	ABCB6_inhibitors	targetBased	0.406539176382971	14	362098	692
uHTS identification of SUMO1-mediated protein-protein interactions	Red cell distribution width	SUMO1	targetBased	0.143195147905874	5	363840	1202
HTS-Luminescent assay for inhibitors of ALR by detection of hydrogen peroxide production Measured in Biochemical System Using Plate Reader - 2036-02_Inhibitor_SinglePoint_HTS	Red cell distribution width	ALR inhibitors	targetBased	0.192728993511032	6	288728	10857
HTS-Luminescent assay for inhibitors of ALR by detection of hydrogen peroxide production Measured in Biochemical System Using Plate Reader - 2036-02_Inhibitor_SinglePoint_HTS	Red cell distribution width	ALR activators	targetBased	0.192728993511032	6	288728	10857
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	Red cell distribution width	PPARG	targetBased	0.491873612372521	14	99314	335
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	Red cell distribution width	PPARG	targetBased	0.491873612372521	14	196176	782
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	Red cell distribution width	PPARG	targetBased	0.491873612372521	14	99314	390
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	Red cell distribution width	PPARG	targetBased	0.491873612372521	14	196177	811
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	Red cell distribution width	PPARG	targetBased	0.491873612372521	14	196176	670
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	Red cell distribution width	PPARG	targetBased	0.491873612372521	14	196177	519
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac activated mutant	Red cell distribution width	RAC1	targetBased	0.229644138363209	6	194629	219
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac wildtype	Red cell distribution width	RAC1	targetBased	0.229644138363209	6	194628	521
Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2	Red cell distribution width	THRB	targetBased	0.507420205788685	11	276265	806
Luminescence Cell-Based Primary HTS to Identify Inhibitors of A1 Apoptosis.	Red cell distribution width	BCL2L11_inhibitors	targetBased	0.165802688022622	8	325630	216
uHTS of small molecular inhibitors for p47phox, a regulatory protein of NADPH oxidases (Noxs)	Red cell distribution width	p47phoxInhibitors	targetBased	0.202260038309932	9	217454	1142
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb via a fluorescence resonance energy transfer (FRET) assay.	Red cell distribution width	RUNX1	targetBased	0.243226101743465	8	215667	993
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay.	Red cell distribution width	RUNX1	targetBased	0.243226101743465	8	218234	1620
Fluorescence-based primary biochemical high throughput screening assay to identify inhibitors of human diacylglycerol lipase, beta (DAGLB)	Red cell distribution width	DAGLB_inhibitors	targetBased	0.448332509745191	17	343468	202
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of human platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (PAFAH1B2)	Red cell distribution width	PAFAH1B2	targetBased	0.137507989763162	9	335239	4158
qHTS Assay for the Inhibitors of Human Flap endonuclease 1 (FEN1).	Red cell distribution width	FEN1_inhibitors	targetBased	0.110905941046679	15	386270	1331
Absorbance-based biochemical primary high throughput screening assay to identify activators of Methionine sulfoxide reductase A (MsrA)	Red cell distribution width	MSRA	targetBased	0.142837228001106	6	362026	1074
Absorbance-based biochemical primary high throughput screening assay to identify inhibitors of Methionine sulfoxide reductase A (MsrA)	Red cell distribution width	MSRA	targetBased	0.142837228001106	6	362577	2709
uHTS identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay	Red cell distribution width	UBE2N	targetBased	0.437058560819275	8	330393	1538
HTS identification of compounds activating phosphomannose isomerase (PMI) via a fluorescence intensity assay using a near- saturating concentration of mannose 6-phosphat	Red cell distribution width	MPI	targetBased	0.215850373473771	8	194152	656
HTS identification of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay using a high concentration of mannose 6-phosphate	Red cell distribution width	MPI	targetBased	0.215850373473771	8	194152	1288
HTS identification of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay.	Red cell distribution width	MPI	targetBased	0.215850373473771	8	194152	814
qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding	Red cell distribution width	MAPT	pathwayBased	0.165580382021032	8	267412	5703
qHTS Assay for Tau Filament Binding	Red cell distribution width	MAPT	targetBased	0.165580382021032	8	69668	1391
qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization	Red cell distribution width	MAPT	pathwayBased	0.165580382021032	8	271402	1048
Primary HTS Assay for S1P3 Antagonists	Red cell distribution width	S1PR3	targetBased	0.460969963106275	15	169141	462
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	Red cell distribution width	JAK2	targetBased	0.558888079392516	14	217959	2390
FRET-based HTS for detection of RAD52 Inhibitors Measured in Biochemical System Using Plate Reader - 7018-01_Inhibitor_SinglePoint_HTS_Activity_Set2	reticulocyte measurement	RAD52	targetBased	0.169253900528092	5	352074	1608
High Content Assay for Compounds that inhibit the Assembly of the Perinucleolar Compartment	reticulocyte measurement	PTBP1	targetBased	0.214277195332374	7	139718	4338
uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (PABP)	reticulocyte measurement	PABPC1	targetBased	0.26211514057418	5	290915	2982
uHTS identification of microRNA-mediated mRNA deadenylation inhibitors by fluoresence polarization assay	reticulocyte measurement	PABPC1	targetBased	0.26211514057418	5	359244	1307
qHTS for Agonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1): primary screen	reticulocyte measurement	RAPGEF3	targetBased	0.187657626954475	7	364614	268
qHTS for Antagonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1): primary screen	reticulocyte measurement	RAPGEF3	targetBased	0.187657626954475	7	364614	517
uHTS identification of small molecule inhibitors of the catalytic domain of the SUMO protease, SENP1 in a FRET assay	reticulocyte measurement	SENP1	targetBased	0.240032736601894	7	363840	774
HTS for Tumor Hsp90 Inhibitors	reticulocyte measurement	HSP90 known inhibitor displacement	targetBased	0.31241266962158	5	63696	220
Luminescence-based primary biochemical high throughput screening assay to identify inhibitors of the Heat Shock Protein 90 (HSP90)	reticulocyte measurement	HSP90AA1	targetBased	0.31241266962158	5	290726	2649
HTS Assay for Peg3 Promoter Inhibitors	reticulocyte measurement	PPP1R15A	targetBased	0.291919272047615	21	359244	6145
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	reticulocyte measurement	JAK2	targetBased	0.592574836962001	16	217959	2390
USP10 deubiquitinase inhibition: Primary qHTS	reticulocyte measurement	USP10	targetBased	0.375300854347039	12	47480	509
Identification of Molecular Probes that Activate MRP-1	reticulocyte measurement	ABCC1_activators	targetBased	0.318487994996415	4	138717	842
uHTS luminescence assay for the identification of compounds that inhibit NOD1	reticulocyte measurement	NOD1	targetBased	0.447644866475735	8	289422	2997
High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Primary Screen	reticulocyte measurement	NFKB1	pathwayBased	0.419624952961124	8	193265	3100
uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay	reticulocyte measurement	NFKB1	pathwayBased	0.419624952961124	8	359244	3094
HTS for Identification of VLA-4 Allosteric Modulators from MLPCN library	reticulocyte measurement	ITGA4	targetBased	0.492793872411107	11	326888	645
HTS of Estrogen Receptor- alpha Coactivator Binding inhibitors	blood phosphate measurement	ESR1_inhibitors	targetBased	0.38380894459827	5	86095	1442
HTS of Estrogen Receptor- alpha Coactivator Binding Potentiators	blood phosphate measurement	ESR1_modulators	targetBased	0.38380894459827	5	86095	1151
uHTS identification of TNAP inhibitors in the absence of phosphate acceptor performed in luminescent assay	blood phosphate measurement	ALPL_inhibitors	targetBased	0.515354604839092	23	195560	517
Primary cell-based high throughput screening assay to measure STAT1 activation	reticulocyte measurement	STAT1 activation	pathwayBased	0.296149745585337	7	195980	5134
Primary cell-based high throughput screening assay to measure STAT1 inhibition	reticulocyte measurement	STAT1	targetBased	0.296149745585337	7	195980	695
qHTS for Inhibitors of Glutaminase (GLS)	reticulocyte measurement	GLS	targetBased	0.440164804858874	9	405291	844
Flow Cytometric HTS Screen for inhibitors of the ABC transporter ABCB6 for MLPCN Compound Set	reticulocyte measurement	ABCB6_inhibitors	targetBased	0.680245557576501	30	362098	692
Primary Cell-Based Assay to Identify Agonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	reticulocyte measurement	S1PR4	targetBased	0.155725252939162	5	217959	771
Primary Cell-Based Assay to Identify Antagonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	reticulocyte measurement	S1PR4	targetBased	0.155725252939162	5	217959	569
uHTS identification of DNMT1 inhibitors in a Fluorescent Molecular Beacon assay	reticulocyte measurement	DNMT1	targetBased	0.312385929611907	19	359244	2975
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	reticulocyte measurement	PPARG	targetBased	0.336613256118835	9	99314	335
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	reticulocyte measurement	PPARG	targetBased	0.336613256118835	9	196176	782
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	reticulocyte measurement	PPARG	targetBased	0.336613256118835	9	99314	390
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	reticulocyte measurement	PPARG	targetBased	0.336613256118835	9	196177	811
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	reticulocyte measurement	PPARG	targetBased	0.336613256118835	9	196176	670
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	reticulocyte measurement	PPARG	targetBased	0.336613256118835	9	196177	519
Luminescence cell-based high throughput primary assay to identify inhibitors of TEAD-YAP interaction.	reticulocyte measurement	YAP1	targetBased	0.340649748043366	4	639428	9218
Inhibitors of CDC25B-CDK2/CyclinA interaction	reticulocyte measurement	Inhibitors of CDC25B-CDK2/CyclinA interaction	targetBased	0.284585556249228	4	93798	679
Fluorescence-based biochemical high throughput primary assay to identify inhibitors of phospholipase C isozymes (PLC-beta3).	reticulocyte measurement	PLCB3	targetBased	0.18954198357306	9	369953	662
Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2	reticulocyte measurement	THRB	targetBased	0.495281884241082	15	276265	806
Luminescence Cell-Based Primary HTS to Identify Inhibitors of A1 Apoptosis.	reticulocyte measurement	BCL2L11_inhibitors	targetBased	0.479743171313257	32	325630	216
uHTS Fluorescent assay for identification of inhibitors of hexokinase domain containing I (HKDC1)	reticulocyte measurement	HKDC1	targetBased	0.36279648490008	13	340696	540
Fluorescence-based primary biochemical high throughput screening assay to identify inhibitors of human diacylglycerol lipase, beta (DAGLB)	reticulocyte measurement	DAGLB_inhibitors	targetBased	0.138059707094405	4	343468	202
uHTS for 14-3-3/Bad interaction inhibitors	reticulocyte measurement	YWHAZ	targetBased	0.465139362675452	13	217332	1549
qHTS Assay for Activators of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease	reticulocyte measurement	GAA	targetBased	0.218287624174214	15	199169	715
qHTS Assay for Inhibitors and Activators of Human alpha-Glucosidase Cleavage of Glycogen	reticulocyte measurement	GAA_inhibitors	targetBased	0.218287624174214	15	302297	1165
Primary cell-based screen for identification of compounds that inhibit the two-pore domain potassium channel KCNK3	reticulocyte measurement	KCNK3	targetBased	0.112444858106985	4	339674	2841
Primary biochemical high throughput screening assay to identify inhibitors of BCL2-related protein, long isoform (BCLXL).	reticulocyte measurement	BCL2L1_modulators	targetBased	0.114415902929479	4	314998	2199
uHTS identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay	reticulocyte measurement	UBE2N	targetBased	0.147784850146855	8	330393	1538
qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding	reticulocyte measurement	MAPT	pathwayBased	0.18938217650541	10	267412	5703
qHTS Assay for Tau Filament Binding	reticulocyte measurement	MAPT	targetBased	0.18938217650541	10	69668	1391
qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization	reticulocyte measurement	MAPT	pathwayBased	0.18938217650541	10	271402	1048
Primary qHTS for Inhibitors of ATXN expression	reticulocyte measurement	ATXN2_repressors	targetBased	0.309036158303271	17	358434	2554
Primary HTS Assay for S1P3 Antagonists	reticulocyte measurement	S1PR3	targetBased	0.330064392182103	11	169141	462
Primary Cell-Based High-Throughput Screening to Identify Agonists of the Sphingosine 1-phosphate receptor 2 (S1P2)	reticulocyte measurement	S1PR2	targetBased	0.601816911607638	34	96879	447
Primary Cell-Based High-Throughput Screening to Identify Antagonists of the Sphingosine 1-phosphate receptor 2 (S1P2)	reticulocyte measurement	S1PR2	targetBased	0.601816911607638	34	96879	207
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	mean reticulocyte volume	JAK2	targetBased	0.604514256128834	8	217959	2390
Identification of Molecular Probes that Activate MRP-1	mean reticulocyte volume	ABCC1_activators	targetBased	0.491167971125891	6	138717	842
HTS for Identification of VLA-4 Allosteric Modulators from MLPCN library	mean reticulocyte volume	ITGA4	targetBased	0.448550901858669	5	326888	645
Flow Cytometric HTS Screen for inhibitors of the ABC transporter ABCB6 for MLPCN Compound Set	mean reticulocyte volume	ABCB6_inhibitors	targetBased	0.25978144799111	9	362098	692
qHTS Assay for NPC1 Promoter Activators	mean reticulocyte volume	NPC1	pathwayBased	0.199433632219593	5	320682	7575
qHTS Assay for Identifying a Potential Treatment of Ataxia-Telangiectasia	mean reticulocyte volume	ATM_modulators	targetBased	0.386988129883748	5	322361	619
Luminescence Cell-Based Primary HTS to Identify Inhibitors of A1 Apoptosis.	mean reticulocyte volume	BCL2L11_inhibitors	targetBased	0.469079571778124	18	325630	216
qHTS Assay for Activators of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease	mean reticulocyte volume	GAA	targetBased	0.282030128483475	6	199169	715
qHTS Assay for Inhibitors and Activators of Human alpha-Glucosidase Cleavage of Glycogen	mean reticulocyte volume	GAA_inhibitors	targetBased	0.282030128483475	6	302297	1165
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	blood disease	JAK2	targetBased	0.102877385792731	24	217959	2390
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	perivascular space measurement	JAK2	targetBased	0.123558356713029	1485	217959	2390
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb via a fluorescence resonance energy transfer (FRET) assay.	platelet storage pool deficiency	RUNX1	targetBased	0.374397805904501	5	215667	993
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay.	platelet storage pool deficiency	RUNX1	targetBased	0.374397805904501	5	218234	1620
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	Thalassemia	JAK2	targetBased	0.152452385728232	32	217959	2390
ROC1-CUL1 CTD Inhibitor di-Ub FRET Primary HTS Screen	Thalassemia	RBX1	targetBased	0.46063880714899	10	143816	859
qHTS for Inhibitors of TGF-b	Thalassemia	TGFB1	pathwayBased	0.476808515418042	20	403345	4970
Fluorescence-based cell-based primary high throughput screening assay to identify agonists of the human cholinergic receptor, muscarinic 1 (CHRM1)	blood coagulation	CHRM1_agonists	targetBased	0.386146281732799	5	359207	1189
Discovery of Novel Allosteric Modulators of the M1 Muscarinic Receptor: Agonist Primary Screen	blood coagulation	CHRM1_allosteric_activators	targetBased	0.386146281732799	5	63676	1938
Fluorescence-based cell-based primary high throughput screening assay to identify positive allosteric modulators (PAMs) of the human M1 muscarinic receptor (CHRM1).	blood coagulation	CHRM1_PAMs	targetBased	0.386146281732799	5	359207	316
Discovery of novel allosteric modulators of the M1 muscarinic receptor: Antagonist Primary Screen	blood coagulation	CHRM1_allosteric_antagonists	targetBased	0.386146281732799	5	63656	2179
Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the human M1 muscarinic receptor (CHRM1)	blood coagulation	CHRM1_antgonists	targetBased	0.386146281732799	5	359207	4555
HTS Assay for Activators of Cytochrome P450 2A9	response to anticoagulant	CYP2C9_activators	targetBased	0.472882309408068	8	95858	1368
CYP2C9 Assay	response to anticoagulant	CYP2C9_inhibitors	targetBased	0.472882309408068	8	95858	18730
CYP2C19 Assay	response to anticoagulant	CYP2C19_inhibitors	targetBased	0.364324340170422	8	95857	20295
qHTS for Inhibitors of TGF-b	Hematuria	TGFB1	pathwayBased	0.289978967398266	8	403345	4970
Inhibitors of the vitamin D receptor (VDR): qHTS	Proteinuria	VDR	targetBased	0.488851155094294	5	394050	3624
HTS for Inhibition of CaV1.3 ICDI/IQ interaction using a live-cell FRET assay Measured in Cell-Based System Using Plate Reader - 7081-01_Inhibitor_SinglePoint_HTS_Activity	Proteinuria	CACNA1D_inhibitors	targetBased	0.413381480411323	5	335531	328
Thrombin 1536 HTS	Abnormality of coagulation	F2_modulation	targetBased	0.136657223112875	27	217233	557
uHTS identification of DNMT1 inhibitors in a Fluorescent Molecular Beacon assay	Abnormality of blood and blood-forming tissues	DNMT1	targetBased	0.366720541489147	6	359244	2975
Counterscreen for Oxytocin Receptor (OXTR) agonists: Fluorescence-based primary cell-based high throughput assay to identify agonists of the vasopressin 1 receptor (V1R)	Abnormality of blood and blood-forming tissues	AVPR1A_agonists	targetBased	0.486648798846447	15	324747	813
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	Abnormality of blood and blood-forming tissues	FGB_inhibitors	targetBased	0.302332864098068	39	369953	760
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	Abnormality of blood and blood-forming tissues	FGB_inhibitors	targetBased	0.302332864098068	39	369953	498
Thrombin 1536 HTS	Abnormality of blood and blood-forming tissues	F2_modulation	targetBased	0.461638545782991	696	217233	557
HCS assay for microtubule stabilizers	Abnormality of blood and blood-forming tissues	TUBB	targetBased	0.134261151163692	7	195821	1625
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	Thrombocytopenia	JAK2	targetBased	0.510664605818772	117	217959	2390
uHTS identification of DNMT1 inhibitors in a Fluorescent Molecular Beacon assay	Thrombocytopenia	DNMT1	targetBased	0.515889133368594	11	359244	2975
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb via a fluorescence resonance energy transfer (FRET) assay.	Thrombocytopenia	RUNX1	targetBased	0.718968650475424	230	215667	993
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay.	Thrombocytopenia	RUNX1	targetBased	0.718968650475424	230	218234	1620
Glucocerebrosidase	Thrombocytopenia	GBA1	targetBased	0.508225184903392	29	48118	549
Thrombin 1536 HTS	Thrombocytopenia	F2_modulation	targetBased	0.653647579537218	492	217233	557
Fluorescence-based cell-based primary high throughput screening assay to identify inhibitors of TLR9-MyD88 binding.	Thrombocytopenia	TLR9	targetBased	0.290290989923939	12	343468	734
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of the interaction of the Ras and Rab interactor 1 protein (Rin1) and the c-abl oncogene 1, non-receptor tyrosine kinase (Abl)	Eosinophilia	ABL1_interaction	targetBased	0.104520972788475	26	359207	1432
Factor XIa 1536 HTS	Abnormal thrombosis	F11_modulation	targetBased	0.425425676424278	50	218707	302
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	Abnormal thrombosis	FGB_inhibitors	targetBased	0.203835231940983	18	369953	760
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	Abnormal thrombosis	FGB_inhibitors	targetBased	0.203835231940983	18	369953	498
Primary cell-based high-throughput screening assay for identification of compounds that inhibit KCNQ1 potassium channels	Iron deficiency anemia	KCNQ1	targetBased	0.238395708392935	6	305610	3878
Primary cell-based high-throughput screening assay for identification of compounds that potentiate/activate KCNQ1 potassium channels	Iron deficiency anemia	KCNQ1	targetBased	0.238395708392935	6	305610	1082
Factor XIa 1536 HTS	Abnormal bleeding	F11_modulation	targetBased	0.536543143506856	12	218707	302
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb via a fluorescence resonance energy transfer (FRET) assay.	Abnormal bleeding	RUNX1	targetBased	0.558431392235399	18	215667	993
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay.	Abnormal bleeding	RUNX1	targetBased	0.558431392235399	18	218234	1620
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	Abnormal bleeding	FGB_inhibitors	targetBased	0.346195062705751	6	369953	760
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	Abnormal bleeding	FGB_inhibitors	targetBased	0.346195062705751	6	369953	498
Glucocerebrosidase	Abnormal bleeding	GBA1	targetBased	0.495180990925095	6	48118	549
Factor XIa 1536 HTS	Thromboembolism	F11_modulation	targetBased	0.315441046304139	29	218707	302
Thrombin 1536 HTS	Thromboembolism	F2_modulation	targetBased	0.563364509169008	126	217233	557
Toxoplasma gondii inhibition HTS in the presence of IFN-y	Aplastic anemia	IFNG	targetBased	0.458482748531067	57	67275	2509
HTS of Estrogen Receptor- alpha Coactivator Binding inhibitors	Microscopic hematuria	ESR1_inhibitors	targetBased	0.507746748108497	5	86095	1442
HTS of Estrogen Receptor- alpha Coactivator Binding Potentiators	Microscopic hematuria	ESR1_modulators	targetBased	0.507746748108497	5	86095	1151
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	Thrombophlebitis	FGB_inhibitors	targetBased	0.187409231417647	4	369953	760
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	Thrombophlebitis	FGB_inhibitors	targetBased	0.187409231417647	4	369953	498
Thrombin 1536 HTS	Thrombophlebitis	F2_modulation	targetBased	0.298201484570625	9	217233	557
Thrombin 1536 HTS	Recurrent thrombophlebitis	F2_modulation	targetBased	0.619285523949174	12	217233	557
Factor XIIa 1536 HTS	Reduced factor XII activity	F12_modulation	targetBased	0.577168330395272	6	217430	649
Factor XIa 1536 HTS	Venous thrombosis	F11_modulation	targetBased	0.221057788012073	64	218707	302
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	Venous thrombosis	JAK2	targetBased	0.309407667002734	81	217959	2390
qHTS for Inhibitors of Cell Surface uPA Generation	Venous thrombosis	PLAU	targetBased	0.156500191664652	17	325247	1021
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	Venous thrombosis	FGB_inhibitors	targetBased	0.416951124692093	24	369953	760
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	Venous thrombosis	FGB_inhibitors	targetBased	0.416951124692093	24	369953	498
Thrombin 1536 HTS	Venous thrombosis	F2_modulation	targetBased	0.656248273264026	522	217233	557
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	Hypofibrinogenemia	FGB_inhibitors	targetBased	0.586030436486814	33	369953	760
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	Hypofibrinogenemia	FGB_inhibitors	targetBased	0.586030436486814	33	369953	498
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of the plasma platelet activating factor acetylhydrolase (pPAFAH)	Platelet-activating factor acetylhydrolase deficiency	PLA2G7	targetBased	0.520209973681166	12	326024	4934
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb via a fluorescence resonance energy transfer (FRET) assay.	inherited bleeding disorder, platelet-type	RUNX1	targetBased	0.380386988995985	25	215667	993
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay.	inherited bleeding disorder, platelet-type	RUNX1	targetBased	0.380386988995985	25	218234	1620
Factor XIa 1536 HTS	coagulation protein disease	F11_modulation	targetBased	0.321328940351622	227	218707	302
Thrombin 1536 HTS	coagulation protein disease	F2_modulation	targetBased	0.295570522045597	245	217233	557
Factor XIa 1536 HTS	hemorrhagic disease	F11_modulation	targetBased	0.314601322438994	263	218707	302
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	hemorrhagic disease	JAK2	targetBased	0.519130401904105	26	217959	2390
qHTS for Inhibitors of Cell Surface uPA Generation	hemorrhagic disease	PLAU	targetBased	0.24534630025438	56	325247	1021
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb via a fluorescence resonance energy transfer (FRET) assay.	hemorrhagic disease	RUNX1	targetBased	0.140123427441867	84	215667	993
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay.	hemorrhagic disease	RUNX1	targetBased	0.140123427441867	84	218234	1620
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	hemorrhagic disease	FGB_inhibitors	targetBased	0.308889011724181	91	369953	760
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	hemorrhagic disease	FGB_inhibitors	targetBased	0.308889011724181	91	369953	498
Thrombin 1536 HTS	hemorrhagic disease	F2_modulation	targetBased	0.356221457011522	454	217233	557
qHTS for Inhibitors of Cell Surface uPA Generation	blood platelet disease	PLAU	targetBased	0.248853628287363	59	325247	1021
qHTS assay for re-activators of p53 using a Luc reporter	blood platelet disease	TP53	pathwayBased	0.132911756518298	36	321427	201
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Nonpermissive Temperature	blood platelet disease	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.132911756518298	36	54509	528
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Permissive Temperature	blood platelet disease	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.132911756518298	36	54513	338
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature	blood platelet disease	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.132911756518298	36	125394	1890
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Permissive Temperature	blood platelet disease	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.132911756518298	36	124022	1156
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb via a fluorescence resonance energy transfer (FRET) assay.	blood platelet disease	RUNX1	targetBased	0.210994215467028	170	215667	993
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay.	blood platelet disease	RUNX1	targetBased	0.210994215467028	170	218234	1620
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	thrombocytosis disease	JAK2	targetBased	0.460273286063998	629	217959	2390
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of the interaction of the Ras and Rab interactor 1 protein (Rin1) and the c-abl oncogene 1, non-receptor tyrosine kinase (Abl)	thrombocytosis disease	ABL1_interaction	targetBased	0.104931214753295	88	359207	1432
EZH2/PRC2 methyltransferase inhibitors Measured in Biochemical System Using Plate Reader - 2125-01_Inhibitor_SinglePoint_HTS_Activity	thrombocytosis disease	EZH2_inhibitors	targetBased	0.331255867471516	12	57013	201
qHTS assay for re-activators of p53 using a Luc reporter	thrombocytosis disease	TP53	pathwayBased	0.262786368759243	20	321427	201
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Nonpermissive Temperature	thrombocytosis disease	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.262786368759243	20	54509	528
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Permissive Temperature	thrombocytosis disease	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.262786368759243	20	54513	338
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature	thrombocytosis disease	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.262786368759243	20	125394	1890
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Permissive Temperature	thrombocytosis disease	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.262786368759243	20	124022	1156
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb via a fluorescence resonance energy transfer (FRET) assay.	thrombocytosis disease	RUNX1	targetBased	0.335165353704902	10	215667	993
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay.	thrombocytosis disease	RUNX1	targetBased	0.335165353704902	10	218234	1620
ROC1-CUL1 CTD Inhibitor di-Ub FRET Primary HTS Screen	anemia	RBX1	targetBased	0.435086994613324	4	143816	859
qHTS for Inhibitors of TGF-b	anemia	TGFB1	pathwayBased	0.41063891878959	58	403345	4970
uHTS identification of DNMT1 inhibitors in a Fluorescent Molecular Beacon assay	anemia	DNMT1	targetBased	0.55367092794918	6	359244	2975
qHTS assay for re-activators of p53 using a Luc reporter	anemia	TP53	pathwayBased	0.194872513693798	215	321427	201
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Nonpermissive Temperature	anemia	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.194872513693798	215	54509	528
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Permissive Temperature	anemia	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.194872513693798	215	54513	338
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature	anemia	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.194872513693798	215	125394	1890
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Permissive Temperature	anemia	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.194872513693798	215	124022	1156
Thrombin 1536 HTS	thrombophilia due to thrombin defect	F2_modulation	targetBased	0.805005841741523	84	217233	557
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	congenital afibrinogenemia	FGB_inhibitors	targetBased	0.876312075943651	206	369953	760
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	congenital afibrinogenemia	FGB_inhibitors	targetBased	0.876312075943651	206	369953	498
Factor XIIa 1536 HTS	congenital factor XII deficiency	F12_modulation	targetBased	0.885973348043109	105	217430	649
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	hypoplasminogenemia	FGB_inhibitors	targetBased	0.105529820865805	5	369953	760
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	hypoplasminogenemia	FGB_inhibitors	targetBased	0.105529820865805	5	369953	498
Counterscreen for Oxytocin Receptor (OXTR) agonists: Fluorescence-based primary cell-based high throughput assay to identify agonists of the vasopressin 1 receptor (V1R)	hemophilia A	AVPR1A_agonists	targetBased	0.577168330395272	6	324747	813
qHTS for Inhibitors of Cell Surface uPA Generation	Quebec platelet disorder	PLAU	targetBased	0.720412492694258	131	325247	1021
Flow Cytometric HTS Screen for inhibitors of the ABC transporter ABCB6 for MLPCN Compound Set	familial pseudohyperkalemia	ABCB6_inhibitors	targetBased	0.751304181752444	20	362098	692
Factor XIa 1536 HTS	congenital factor XI deficiency	F11_modulation	targetBased	0.928341461537528	543	218707	302
Thrombin 1536 HTS	congenital prothrombin deficiency	F2_modulation	targetBased	0.877708103951809	440	217233	557
qHTS Assay for Identification of Novel General Anesthetics	L-ferritin deficiency	FTL	targetBased	0.67761879609898	14	341499	255
qHTS assay for re-activators of p53 using a Luc reporter	Diamond-Blackfan anemia	TP53	pathwayBased	0.468404054702342	134	321427	201
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Nonpermissive Temperature	Diamond-Blackfan anemia	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.468404054702342	134	54509	528
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Permissive Temperature	Diamond-Blackfan anemia	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.468404054702342	134	54513	338
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature	Diamond-Blackfan anemia	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.468404054702342	134	125394	1890
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Permissive Temperature	Diamond-Blackfan anemia	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.468404054702342	134	124022	1156
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	aplastic anemia	JAK2	targetBased	0.278002873100202	229	217959	2390
Toxoplasma gondii inhibition HTS in the presence of IFN-y	aplastic anemia	IFNG	targetBased	0.163228611834967	137	67275	2509
qHTS assay for re-activators of p53 using a Luc reporter	aplastic anemia	TP53	pathwayBased	0.193116196880461	165	321427	201
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Nonpermissive Temperature	aplastic anemia	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.193116196880461	165	54509	528
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Permissive Temperature	aplastic anemia	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.193116196880461	165	54513	338
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature	aplastic anemia	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.193116196880461	165	125394	1890
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Permissive Temperature	aplastic anemia	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.193116196880461	165	124022	1156
Primary biochemical high throughput screening assay to identify inhibitors of BCL2-related protein, long isoform (BCLXL).	aplastic anemia	BCL2L1_modulators	targetBased	0.133318583514122	9	314998	2199
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	familial dysfibrinogenemia	FGB_inhibitors	targetBased	0.817497971692264	115	369953	760
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	familial dysfibrinogenemia	FGB_inhibitors	targetBased	0.817497971692264	115	369953	498
Primary biochemical high throughput screening assay to identify inhibitors of BCL2-related protein, long isoform (BCLXL).	autosomal dominant macrothrombocytopenia	BCL2L1_modulators	targetBased	0.106748935809879	15	314998	2199
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	familial hypodysfibrinogenemia	FGB_inhibitors	targetBased	0.594921821134701	17	369953	760
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	familial hypodysfibrinogenemia	FGB_inhibitors	targetBased	0.594921821134701	17	369953	498
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	congenital fibrinogen deficiency	FGB_inhibitors	targetBased	0.589911108501056	90	369953	760
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	congenital fibrinogen deficiency	FGB_inhibitors	targetBased	0.589911108501056	90	369953	498
Factor XIa 1536 HTS	hemophilia	F11_modulation	targetBased	0.322301174710457	220	218707	302
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	familial thrombocytosis	JAK2	targetBased	0.420462164606461	22	217959	2390
Thrombin 1536 HTS	prothrombin deficiency	F2_modulation	targetBased	0.764218597299019	588	217233	557
Factor XIa 1536 HTS	factor XI deficiency	F11_modulation	targetBased	0.855157966549838	264	218707	302
Thrombin 1536 HTS	inherited thrombophilia	F2_modulation	targetBased	0.278763968488388	77	217233	557
HTS of Estrogen Receptor- alpha Coactivator Binding inhibitors	hemorrhage	ESR1_inhibitors	targetBased	0.618589591189615	43	86095	1442
HTS of Estrogen Receptor- alpha Coactivator Binding Potentiators	hemorrhage	ESR1_modulators	targetBased	0.618589591189615	43	86095	1151
Counterscreen for Oxytocin Receptor (OXTR) agonists: Fluorescence-based primary cell-based high throughput assay to identify agonists of the vasopressin 1 receptor (V1R)	hemorrhage	AVPR1A_agonists	targetBased	0.648280443805337	36	324747	813
HTS for Beta-2AR agonists via FAP method	hemorrhage	ADRB2_activators	targetBased	0.621256851051645	22	339297	1446
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	hemorrhage	FGB_inhibitors	targetBased	0.612062449884587	18	369953	760
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	hemorrhage	FGB_inhibitors	targetBased	0.612062449884587	18	369953	498
Thrombin 1536 HTS	hemorrhage	F2_modulation	targetBased	0.377468552790413	91	217233	557
Fluorescence-based primary cell-based high throughput screening assay to identify agonists of the Oxytocin Receptor (OXTR).	hemorrhage	OXTR	targetBased	0.638135094889748	55	324747	1043
Allosteric Agonists of the Human D1 Dopamine Receptor: qHTS	hemorrhage	D1_activators	targetBased	0.655846725244634	54	361330	3713
Allosteric Modulators of D1 Receptors: Primary Screen	hemorrhage	D1	targetBased	0.655846725244634	54	57705	3413
Antagonist of Human D 1 Dopamine Receptor: qHTS	hemorrhage	D1_inhibitors	targetBased	0.655846725244634	54	355805	11440
HTS Assay for Compounds that Act as Agonists of the Vanilloid Receptor 1	hemorrhage	TRPV1	targetBased	0.543561973515538	7	316642	617
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb via a fluorescence resonance energy transfer (FRET) assay.	Rare hemorrhagic disorder due to a constitutional platelet anomaly	RUNX1	targetBased	0.177405670039851	18	215667	993
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay.	Rare hemorrhagic disorder due to a constitutional platelet anomaly	RUNX1	targetBased	0.177405670039851	18	218234	1620
Thrombin 1536 HTS	Von Willebrand disease	F2_modulation	targetBased	0.106166078322928	19	217233	557
Thrombin 1536 HTS	Congenital factor II deficiency	F2_modulation	targetBased	0.848343511620626	104	217233	557
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb via a fluorescence resonance energy transfer (FRET) assay.	Platelet storage pool disease	RUNX1	targetBased	0.379869224113787	10	215667	993
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay.	Platelet storage pool disease	RUNX1	targetBased	0.379869224113787	10	218234	1620
Discovery of small molecule inhibitors of the oncogenic and cytokinetic protein MgcRacGAP - Primary and Confirmatory Screens	Congenital dyserythropoietic anemia type III	RACGAP1	targetBased	0.408246236743248	5	342059	2057
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	Familial afibrinogenemia	FGB_inhibitors	targetBased	0.849937604123244	24	369953	760
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	Familial afibrinogenemia	FGB_inhibitors	targetBased	0.849937604123244	24	369953	498
Toxoplasma gondii inhibition HTS in the presence of IFN-y	anemia (phenotype)	IFNG	targetBased	0.154963003559386	31	67275	2509
Identification of Small Molecule Correctors of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Delta508 Mutation Function in Human Bronchial Epithelial Cells. Measured in Cell-Based System Using Plate Reader - 7017-01_Other_SinglePoint_HTS_Activity	hematological measurement	cftrCorrectors	targetBased	0.109384852035677	8	343786	1253
Fluorescence Polarization with CAL-PDZ Measured in Biochemical System Using Plate Reader - 2109-02_Inhibitor_SinglePoint_HTS_Activity	hematological measurement	cftrTrafficModulators	targetBased	0.109384852035677	8	296501	2737
FRET-based HTS for detection of RAD52 Inhibitors Measured in Biochemical System Using Plate Reader - 7018-01_Inhibitor_SinglePoint_HTS_Activity_Set2	hematological measurement	RAD52	targetBased	0.156488704784529	15	352074	1608
HTS for developing T Cell Immune Modulators	hematological measurement	ITGAL	targetBased	0.168578258352626	31	326271	221
Identification of agents that induce E-selectin on human endothelial cells Measured in Cell-Based System Using Imaging - 2152-01_Activator_SinglePoint_HTS_Activity	hematological measurement	SELE	targetBased	0.10824457624726	17	257988	963
Primary HTS assay for chemical inhibitors of TNF alpha stimulated E-Selectin expression	hematological measurement	E-selectinExpression	targetBased	0.10824457624726	17	118096	843
High Content Assay for Compounds that inhibit the Assembly of the Perinucleolar Compartment	hematological measurement	PTBP1	targetBased	0.155335618669448	27	139718	4338
Fluorescence-based primary biochemical high throughput screening assay to identify inhibitors of Protein Phosphatase 5 (PP5).	hematological measurement	PPP5C	targetBased	0.151722535520938	13	314999	564
ARNT-TAC3: AlphaScreen HTS to detect disruption of ARNT/TAC3 interactions Measured in Biochemical System Using Plate Reader - 2158-01_Inhibitor_SinglePoint_HTS_Activity	hematological measurement	TACC3	targetBased	0.108534152309881	5	391179	2589
USP28 deubiquitinase inhibition: Primary qHTS	hematological measurement	USP28	targetBased	0.131041619327977	5	47480	1413
Primary cell-based high-throughput screening assay for identification of compounds that inhibit KCNQ1 potassium channels	hematological measurement	KCNQ1	targetBased	0.174654970028923	16	305610	3878
Primary cell-based high-throughput screening assay for identification of compounds that potentiate/activate KCNQ1 potassium channels	hematological measurement	KCNQ1	targetBased	0.174654970028923	16	305610	1082
Primary Cell-based High Throughput Screening assay for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA)	hematological measurement	RORA	pathwayBased	0.174033092183465	20	64908	979
Primary Cell-based High Throughput Screening assay for inhibitors of the Retinoic Acid Receptor-related orphan receptor A (RORA)	hematological measurement	RORA	pathwayBased	0.174033092183465	20	64908	278
uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (PABP)	hematological measurement	PABPC1	targetBased	0.112718756573722	7	290915	2982
uHTS identification of microRNA-mediated mRNA deadenylation inhibitors by fluoresence polarization assay	hematological measurement	PABPC1	targetBased	0.112718756573722	7	359244	1307
HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Inhibitor_SinglePoint_HTS_Activity	hematological measurement	SCARB1	targetBased	0.215892018414903	19	319204	3065
HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Activator_SinglePoint_HTS_Activity	hematological measurement	SCARB1	targetBased	0.215892018414903	19	316970	306
HTS to identify compounds that promote myeloid differentiation with MLPCN compound set	hematological measurement	HOXA9	pathwayBased	0.158764246046626	27	358556	3721
qHTS for Agonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1): primary screen	hematological measurement	RAPGEF3	targetBased	0.119221494716323	22	364614	268
qHTS for Antagonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1): primary screen	hematological measurement	RAPGEF3	targetBased	0.119221494716323	22	364614	517
Luminescence-based cell-based primary high throughput screening assay to identify activators of the function of SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 (SMARCA2, BRM)	hematological measurement	SMARCA2	targetBased	0.129330241139257	7	368927	3838
HTS for Tumor Hsp90 Inhibitors	hematological measurement	HSP90 known inhibitor displacement	targetBased	0.129938002807169	17	63696	220
Luminescence-based primary biochemical high throughput screening assay to identify inhibitors of the Heat Shock Protein 90 (HSP90)	hematological measurement	HSP90AA1	targetBased	0.129938002807169	17	290726	2649
Luminescence-based cell-based primary high throughput screening assay to identify inhibitors of the Steroid Receptor Coactivator 1 (SRC1; NCOA1)	hematological measurement	NCOA1	targetBased	0.1346285043786	4	359206	428
HTS Assay for Peg3 Promoter Inhibitors	hematological measurement	PPP1R15A	targetBased	0.158676800900732	27	359244	6145
qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS	hematological measurement	GNAS	targetBased	0.132775112499544	14	334825	423
qHTS for Antagonists of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS	hematological measurement	GNAS	targetBased	0.132775112499544	14	337446	1356
Factor XIa 1536 HTS	hematological measurement	F11_modulation	targetBased	0.208602804589592	4	218707	302
HTS of Estrogen Receptor- alpha Coactivator Binding inhibitors	hematological measurement	ESR1_inhibitors	targetBased	0.15649580132436	40	86095	1442
HTS of Estrogen Receptor- alpha Coactivator Binding Potentiators	hematological measurement	ESR1_modulators	targetBased	0.15649580132436	40	86095	1151
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	hematological measurement	JAK2	targetBased	0.268450856077669	149	217959	2390
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of the interaction of the Ras and Rab interactor 1 protein (Rin1) and the c-abl oncogene 1, non-receptor tyrosine kinase (Abl)	hematological measurement	ABL1_interaction	targetBased	0.149755226070365	14	359207	1432
uHTS identification of modulators of interaction between CendR and NRP-1 using Fluorescence Polarization assay	hematological measurement	NRP1	targetBased	0.156278190984974	4	363840	3086
Identification of CBX7 inhibitors - Primary Alpha Screen	hematological measurement	Chromobox protein homolog 7 inhibitors	targetBased	0.166951406142546	20	64999	724
qHTS for Inhibitors of Polymerase Iota	hematological measurement	POLI	targetBased	0.123915057946601	30	386063	3989
qHTS Assay for Inhibitors of the CtBP/E1A Interaction	hematological measurement	RBBP8	targetBased	0.138209365020396	10	335214	1652
USP10 deubiquitinase inhibition: Primary qHTS	hematological measurement	USP10	targetBased	0.141852739808323	9	47480	509
Identification of Molecular Probes that Activate MRP-1	hematological measurement	ABCC1_activators	targetBased	0.190469284376082	27	138717	842
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype	hematological measurement	RAB2A	targetBased	0.15724795673302	11	194628	365
qHTS for Inhibitors of TGF-b	hematological measurement	TGFB1	pathwayBased	0.118298222809687	556	403345	4970
uHTS luminescence assay for the identification of compounds that inhibit NOD1	hematological measurement	NOD1	targetBased	0.172466742916534	10	289422	2997
EZH2/PRC2 methyltransferase inhibitors Measured in Biochemical System Using Plate Reader - 2125-01_Inhibitor_SinglePoint_HTS_Activity	hematological measurement	EZH2_inhibitors	targetBased	0.150472794584119	17	57013	201
Luminescence-based primary cell-based high throughput screening assay to identify activators of the Aryl Hydrocarbon Receptor (AHR)	hematological measurement	AHR_activators	targetBased	0.164770447980392	14	324747	7988
Fluorescence Biochemical Primary HTS to Identify Inhibitors of GASC-1 Activity	hematological measurement	KDM4C	targetBased	0.159850065990817	12	326066	228
Primary qHTS assay for inhibitors of human arachidonate 12S-lipoxygenase (ALOX12): Round 2	hematological measurement	ALOX12_inhibitors	targetBased	0.106373154574424	6	564288	6030
High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Primary Screen	hematological measurement	NFKB1	pathwayBased	0.195782410830686	109	193265	3100
uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay	hematological measurement	NFKB1	pathwayBased	0.195782410830686	109	359244	3094
qHTS of IL-2 Activators	hematological measurement	IL2	targetBased	0.124201244270411	50	364617	238
Inhibitors of the vitamin D receptor (VDR): qHTS	hematological measurement	VDR	targetBased	0.144640203839611	25	394050	3624
Toxoplasma gondii inhibition HTS in the presence of IFN-y	hematological measurement	IFNG	targetBased	0.182357695218167	139	67275	2509
qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode)	hematological measurement	GLP1R	targetBased	0.153358206298802	12	405130	6428
qHTS of GLP-1 Receptor Agonists	hematological measurement	GLP1R agonists	targetBased	0.153358206298802	12	373462	23
qHTS of GLP-1 Receptor Inverse Agonists: (PAM Mode) (Taking the negative queue for PAMs)	hematological measurement	GLP1R PAMs	targetBased	0.153358206298802	12	405130	6428
uHTS identification of small molecule antagonists of the CCR6 receptor via a luminescent beta-arrestin assay	hematological measurement	CCR6_antagonists	targetBased	0.164714130412727	5	340696	1654
HTS for Identification of VLA-4 Allosteric Modulators from MLPCN library	hematological measurement	ITGA4	targetBased	0.207002829314092	83	326888	645
Primary cell-based high throughput screening assay to measure STAT1 activation	hematological measurement	STAT1 activation	pathwayBased	0.173474023037444	27	195980	5134
Primary cell-based high throughput screening assay to measure STAT1 inhibition	hematological measurement	STAT1	targetBased	0.173474023037444	27	195980	695
qHTS for Inhibitors of Glutaminase (GLS)	hematological measurement	GLS	targetBased	0.183026426456845	19	405291	844
Small-molecule inhibitors of ST2 (IL1RL1)	hematological measurement	IL1RL1	targetBased	0.184266923914793	29	75924	1804
Flow Cytometric HTS Screen for inhibitors of the ABC transporter ABCB6 for MLPCN Compound Set	hematological measurement	ABCB6_inhibitors	targetBased	0.241771175271245	45	362098	692
uHTS identification of HIF-2a Inhibitors in a luminesence assay	hematological measurement	HIF-2a_inhibitors	targetBased	0.184248716902906	83	363840	2624
Luminescence-based cell-based primary high throughput screening assay to identify inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2)	hematological measurement	NR5A2	targetBased	0.182542540728361	9	363803	458
Fluorescence polarization-based cell-based primary high throughput screening assay to identify activators of insulin-degrading enzyme (IDE)	hematological measurement	IDE	targetBased	0.113790739106224	11	335239	245
Fluorescence polarization-based cell-based primary high throughput screening assay to identify inhibitors of insulin-degrading enzyme (IDE)	hematological measurement	IDE	targetBased	0.113790739106224	11	324747	1316
uHTS identification of Caspase-8 TRAIL sensitizers in a luminesence assay	hematological measurement	TNFRSF10B	targetBased	0.163404243464917	18	363840	3764
Antagonist identification of Pyk2 oligomerization: high-throughput screening cellular assay	hematological measurement	Pyk2Ã‚Â	targetBased	0.127557590968756	12	98749	818
uHTS for the identification of compounds that potentiate TRAIL-induced apoptosis of cancer cells	hematological measurement	TNFSF10	targetBased	0.187342462898805	26	217035	883
qHTS Assay for Inhibitors of BAZ2B	hematological measurement	BAZ2B_modulators	targetBased	0.166686236378446	19	356826	15709
Primary cell-based high-throughput screening assay for identification of compounds that inhibit/block inward-rectifying potassium ion channel Kir2.1	hematological measurement	KCNJ2	targetBased	0.179399289081565	9	305610	2592
Fluorescence-based biochemical high throughput primary assay to identify inhibitors of phospholipase C isozymes (PLC-gamma1).	hematological measurement	PLCG1	targetBased	0.174337022662958	14	369953	3123
MLPCN SirT-5 Measured in Biochemical System Using Imaging - 7044-01_Inhibitor_SinglePoint_HTS_Activity_Set5	hematological measurement	SIRT5	targetBased	0.131422538495515	12	323507	3752
HTS for PAX8 inhibitors using PAX8 luciferase reporter gene assay in RMG-I cells Measured in Cell-Based System Using Plate Reader - 7054-01_Inhibitor_SinglePoint_HTS_Activity	hematological measurement	PAX8	targetBased	0.15820261574423	44	353950	4145
Primary Cell-Based Assay to Identify Agonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	hematological measurement	S1PR4	targetBased	0.256545540986611	64	217959	771
Primary Cell-Based Assay to Identify Antagonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	hematological measurement	S1PR4	targetBased	0.256545540986611	64	217959	569
uHTS identification of APOBEC3A DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay	hematological measurement	APOBEC3A_inhibitors	targetBased	0.122853471636628	5	331753	1372
Fluorescence-based biochemical primary high throughput screening assay to identify activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF)	hematological measurement	TNNI3	targetBased	0.134977293407528	11	335239	801
Fluorescence-based biochemical primary high throughput screening assay to identify inhibitors of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF)	hematological measurement	TNNI3	targetBased	0.134977293407528	11	335238	390
uHTS identification of DNMT1 inhibitors in a Fluorescent Molecular Beacon assay	hematological measurement	DNMT1	targetBased	0.114851450367204	37	359244	2975
Primary cell-based high-throughput screening for identification of compounds that inhibit/block calcium-activated chloride channels (TMEM16A)	hematological measurement	ANO1_inhibitors	targetBased	0.134743495851305	11	306502	3633
Primary cell-based high-throughput screening for identification of compounds that activate/potentiate calcium-activated chloride channels (TMEM16A)	hematological measurement	ANO1_activators	targetBased	0.134743495851305	11	335180	1022
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	hematological measurement	PPARG	targetBased	0.187799631936044	98	99314	335
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	hematological measurement	PPARG	targetBased	0.187799631936044	98	196176	782
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	hematological measurement	PPARG	targetBased	0.187799631936044	98	99314	390
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	hematological measurement	PPARG	targetBased	0.187799631936044	98	196177	811
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	hematological measurement	PPARG	targetBased	0.187799631936044	98	196176	670
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	hematological measurement	PPARG	targetBased	0.187799631936044	98	196177	519
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of 5-meCpG-binding domain protein 2 (MBD2)-DBD binding to methylated oligonucleotide	hematological measurement	MBD2	targetBased	0.158936731667981	26	369953	1149
USP30 deubiquitinase inhibition: Primary qHTS	hematological measurement	USP30	targetBased	0.133974119198368	7	47480	2500
qHTS for Activators of Integrin-Mediated Alleviation for Muscular Dystrophy	hematological measurement	CGA_integrin_activators	targetBased	0.127112293017039	21	345855	222
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac activated mutant	hematological measurement	RAC1	targetBased	0.111232471792223	8	194629	219
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac wildtype	hematological measurement	RAC1	targetBased	0.111232471792223	8	194628	521
High throughput screening of activators of transient receptor potential cation channel C6 (TRPC6)	hematological measurement	TRPC6	targetBased	0.184714836343293	12	305610	382
High throughput screening of inhibitors of transient receptor potential cation channel C6 (TRPC6)	hematological measurement	TRPC6	targetBased	0.184714836343293	12	305610	3253
QFRET-based biochemical primary high throughput screening assay to identify exosite inhibitors of ADAM10.	hematological measurement	ADAM10_inhibitors	targetBased	0.100332346572728	10	369953	2294
HTS Assay for Activators of Cytochrome P450 2A9	hematological measurement	CYP2C9_activators	targetBased	0.136629724212791	5	95858	1368
CYP2C9 Assay	hematological measurement	CYP2C9_inhibitors	targetBased	0.136629724212791	5	95858	18730
uHTS Luminescent assay for identification of inhibitors of Sentrin-specific protease 7 (SENP7)	hematological measurement	SENP7	targetBased	0.155694902785629	20	331670	4902
HTS for Estrogen Receptor-beta Coactivator Binding inhibitors	hematological measurement	ESR2_inhibitors	targetBased	0.197063736225472	17	86095	1114
Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bfl-1	hematological measurement	BCL2A1_modulators	targetBased	0.171236685712178	32	194826	237
Luminescence-based cell-based primary high throughput screening assay to identify inhibitors of the Steroid Receptor Coactivator 2 (SRC2; NCOA2)	hematological measurement	NCOA2	targetBased	0.150810514610509	6	368927	620
qHTS assay for re-activators of p53 using a Luc reporter	hematological measurement	TP53	pathwayBased	0.108432777367689	139	321427	201
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Nonpermissive Temperature	hematological measurement	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.108432777367689	139	54509	528
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Permissive Temperature	hematological measurement	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.108432777367689	139	54513	338
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature	hematological measurement	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.108432777367689	139	125394	1890
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Permissive Temperature	hematological measurement	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.108432777367689	139	124022	1156
HTS Assay for Inhibitors of Akt Phophorylation: Primary Screen	hematological measurement	AKT1_inhibitors	targetBased	0.114465047383652	98	356517	1139
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of myeloid cell leukemia sequence 1 (MCL1) interactions with BIM-BH3 peptide.	hematological measurement	MCL1	targetBased	0.110014180103689	39	314998	2139
uHTS of Mcl-1/Bid interaction inhibitors	hematological measurement	MCL1	targetBased	0.110014180103689	39	218602	2129
uHTS of Mcl-1/Noxa interaction inhibitors	hematological measurement	MCL1	targetBased	0.110014180103689	39	217330	3334
HTS Discovery of Chemical Inhibitors of HePTP, a Leukemia Target	hematological measurement	PTPN7	targetBased	0.161016276860681	5	112381	724
Inhibitors of CDC25B-CDK2/CyclinA interaction	hematological measurement	Inhibitors of CDC25B-CDK2/CyclinA interaction	targetBased	0.16912531069505	28	93798	679
qHTS Assay for Identifying a Potential Treatment of Ataxia-Telangiectasia	hematological measurement	ATM_modulators	targetBased	0.212862068673016	67	322361	619
Fluorescence-based biochemical high throughput primary assay to identify inhibitors of phospholipase C isozymes (PLC-beta3).	hematological measurement	PLCB3	targetBased	0.149036143642968	27	369953	662
qHTS for Inhibitors of phosphatidylinositol 5-phosphate 4-kinase (PI5P4K)	hematological measurement	PIP4K2A	targetBased	0.133656870180507	5	328860	4078
Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2	hematological measurement	THRB	targetBased	0.18473520554782	51	276265	806
uHTS identification of small molecule inhibitors of Artemis endonuclease activity via a fluorescence intensity assay	hematological measurement	artemis_inhibitors	targetBased	0.140678568091937	4	30104	235
Luminescence Cell-Based Primary HTS to Identify Inhibitors of A1 Apoptosis.	hematological measurement	BCL2L11_inhibitors	targetBased	0.188603387926108	190	325630	216
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors of ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 (ASAP1)	hematological measurement	ASAP1_inhibitors	targetBased	0.176757737804786	9	362577	680
uHTS Fluorescent assay for identification of inhibitors of hexokinase domain containing I (HKDC1)	hematological measurement	HKDC1	targetBased	0.185643883581296	70	340696	540
Dyrk1 A HTS Measured in Biochemical System Using Plate Reader - 2124-01_Inhibitor_SinglePoint_HTS_Activity	hematological measurement	DYRK1A_inhibitors	targetBased	0.15727413899872	21	310014	1321
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb via a fluorescence resonance energy transfer (FRET) assay.	hematological measurement	RUNX1	targetBased	0.199962825916887	92	215667	993
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay.	hematological measurement	RUNX1	targetBased	0.199962825916887	92	218234	1620
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of Protein Arginine Deiminase 4 (PAD4) (1536 HTS)	hematological measurement	PADI4	targetBased	0.167796524459931	8	326022	1334
HTS identification of compounds inhibiting the binding of CD11b/CD18 to fibrinogen via a luminescence assay.	hematological measurement	ITGB2	targetBased	0.167398483164232	8	92518	501
qHTS for PTHR1 Agonists: Primary Screen	hematological measurement	PTH1R	targetBased	0.115742319816214	8	405685	308
qHTS Assay for Inhibitors of 15-hLO (15-human lipoxygenase)	hematological measurement	ALOX15_inhibitors	targetBased	0.249107373413852	30	73174	1034
Inhibitors of USP1/UAF1: Primary Screen	hematological measurement	USP1	targetBased	0.129251885364037	19	389569	904
uHTS Luminescent assay for identification of inhibitors of NALP3 in yeast	hematological measurement	NLRP3	targetBased	0.234492925114746	69	330392	1295
High Content Assay for Compounds that inhibit the Assembly of the Perinucleolar Compartment	erythrocyte indices	PTBP1	targetBased	0.126510743024722	5	139718	4338
HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Inhibitor_SinglePoint_HTS_Activity	erythrocyte indices	SCARB1	targetBased	0.178436333330801	7	319204	3065
HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Activator_SinglePoint_HTS_Activity	erythrocyte indices	SCARB1	targetBased	0.178436333330801	7	316970	306
HTS to identify compounds that promote myeloid differentiation with MLPCN compound set	erythrocyte indices	HOXA9	pathwayBased	0.155766157604449	9	358556	3721
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	erythrocyte indices	JAK2	targetBased	0.173013817997149	27	217959	2390
qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)	hematological measurement	HPGD	targetBased	0.132223769895154	4	148480	6428
Fluorescence-based primary biochemical high throughput screening assay to identify inhibitors of human diacylglycerol lipase, beta (DAGLB)	hematological measurement	DAGLB_inhibitors	targetBased	0.173229153653124	38	343468	202
uHTS for 14-3-3/Bad interaction inhibitors	hematological measurement	YWHAZ	targetBased	0.17290005067094	11	217332	1549
Primary biochemical high-throughput screening assay to measure P97 ATPase inhibition	hematological measurement	VCP	targetBased	0.154025077592593	18	217959	923
CYP2C19 Assay	hematological measurement	CYP2C19_inhibitors	targetBased	0.145222031934587	8	95857	20295
Primary Cell-based High Throughput Screening Assay for Inhibitors of Wee1 Degradation	hematological measurement	WEE1	targetBased	0.133111643487394	25	217959	2616
Luminescence-based cell-based primary high throughput screening assay to identify biased ligands of the melanocortin 4 receptor (MC4R): agonists of MC4R	hematological measurement	MC4R	targetBased	0.132745257269043	6	356160	3470
TRFRET-based cell-based primary high throughput screening assay to identify biased ligands of the melanocortin 4 receptor (MC4R): antagonists of MC4R	hematological measurement	MC4R	targetBased	0.132745257269043	6	356160	1703
Fluorescence polarization assay for PLK1 inhibitors	hematological measurement	PLK1	targetBased	0.166126704542982	6	97099	518
qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen	hematological measurement	PLK1	targetBased	0.166126704542982	6	364065	10181
HTS of Smad transcription factor inhibitors	hematological measurement	SMAD3	targetBased	0.1935418470155	56	88033	251
Primary cell-based high throughput screening assay to measure STAT3 activation	hematological measurement	STAT3	pathwayBased	0.144903545734767	64	194666	1772
Primary cell-based high throughput screening assay to measure STAT3 inhibition	hematological measurement	STAT3	pathwayBased	0.144903545734767	64	194666	1722
HTS for Beta-2AR agonists via FAP method	hematological measurement	ADRB2_activators	targetBased	0.187129065461212	34	339297	1446
Primary biochemical high-throughput screening assay for inhibitors of Focal Adhesion Kinase (FAK)	hematological measurement	PTK2	targetBased	0.154075418045664	17	96879	811
qHTS for Inhibitors of Polymerase Iota	erythrocyte indices	POLI	targetBased	0.102539872150895	12	386063	3989
uHTS luminescence assay for the identification of compounds that inhibit NOD1	erythrocyte indices	NOD1	targetBased	0.163560746253176	4	289422	2997
EZH2/PRC2 methyltransferase inhibitors Measured in Biochemical System Using Plate Reader - 2125-01_Inhibitor_SinglePoint_HTS_Activity	erythrocyte indices	EZH2_inhibitors	targetBased	0.137409930776384	5	57013	201
Fluorescence Biochemical Primary HTS to Identify Inhibitors of GASC-1 Activity	erythrocyte indices	KDM4C	targetBased	0.149405206600185	6	326066	228
High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Primary Screen	erythrocyte indices	NFKB1	pathwayBased	0.180470960689835	9	193265	3100
uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay	erythrocyte indices	NFKB1	pathwayBased	0.180470960689835	9	359244	3094
HTS for Identification of VLA-4 Allosteric Modulators from MLPCN library	erythrocyte indices	ITGA4	targetBased	0.165007304365153	6	326888	645
uHTS identification of HIF-2a Inhibitors in a luminesence assay	erythrocyte indices	HIF-2a_inhibitors	targetBased	0.151520389556966	21	363840	2624
uHTS identification of Caspase-8 TRAIL sensitizers in a luminesence assay	erythrocyte indices	TNFRSF10B	targetBased	0.157104868237044	7	363840	3764
Fluorescence-based biochemical high throughput primary assay to identify inhibitors of phospholipase C isozymes (PLC-gamma1).	erythrocyte indices	PLCG1	targetBased	0.151192815658594	4	369953	3123
HTS for PAX8 inhibitors using PAX8 luciferase reporter gene assay in RMG-I cells Measured in Cell-Based System Using Plate Reader - 7054-01_Inhibitor_SinglePoint_HTS_Activity	erythrocyte indices	PAX8	targetBased	0.142014999984523	4	353950	4145
Primary Cell-Based Assay to Identify Agonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	erythrocyte indices	S1PR4	targetBased	0.117979848288467	4	217959	771
Primary Cell-Based Assay to Identify Antagonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	erythrocyte indices	S1PR4	targetBased	0.117979848288467	4	217959	569
uHTS identification of small molecule antagonists of the EBI2 receptor via a luminescent beta-arrestin assay	hematological measurement	GPR183	targetBased	0.121830949173039	13	363840	2946
Primary HTS and Confirmation Assays for S1P1 Agonists and Agonism Potentiators	hematological measurement	S1PR1	targetBased	0.198148884027195	46	55710	315
qHTS Assay for Activators of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease	hematological measurement	GAA	targetBased	0.157240662704849	26	199169	715
qHTS Assay for Inhibitors and Activators of Human alpha-Glucosidase Cleavage of Glycogen	hematological measurement	GAA_inhibitors	targetBased	0.157240662704849	26	302297	1165
Primary cell-based screen for identification of compounds that inhibit the two-pore domain potassium channel KCNK3	hematological measurement	KCNK3	targetBased	0.135609825535155	7	339674	2841
Primary biochemical high throughput screening assay to identify inhibitors of BCL2-related protein, long isoform (BCLXL).	hematological measurement	BCL2L1_modulators	targetBased	0.182423413576256	41	314998	2199
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	hematological measurement	FGB_inhibitors	targetBased	0.201934473667419	17	369953	760
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	hematological measurement	FGB_inhibitors	targetBased	0.201934473667419	17	369953	498
Inhibition of the MLL-AF4-AF9 Interaction in Pediatric Leukemia Measured in Biochemical System Using Plate Reader - 2160-01_Inhibitor_SinglePoint_HTS_Activity	hematological measurement	MLLT3	targetBased	0.183070748519513	14	344459	1627
qHTS for Small Molecule Agonists and Allosteric Enhancers of Human TRH Receptor: Primary Screen for Agonists.	hematological measurement	TRHR	targetBased	0.125716357354088	4	361330	651
qHTS for Small Molecule Agonists and Allosteric Enhancers of Human TRH Receptor: Primary Screen for Enhancers	hematological measurement	TRHR	targetBased	0.125716357354088	4	361330	2424
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	erythrocyte indices	PPARG	targetBased	0.173135371715778	13	99314	335
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	erythrocyte indices	PPARG	targetBased	0.173135371715778	13	196176	782
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	erythrocyte indices	PPARG	targetBased	0.173135371715778	13	99314	390
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	erythrocyte indices	PPARG	targetBased	0.173135371715778	13	196177	811
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	erythrocyte indices	PPARG	targetBased	0.173135371715778	13	196176	670
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	erythrocyte indices	PPARG	targetBased	0.173135371715778	13	196177	519
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of 5-meCpG-binding domain protein 2 (MBD2)-DBD binding to methylated oligonucleotide	erythrocyte indices	MBD2	targetBased	0.155039196518194	11	369953	1149
E3 Ligase HTS_1536	erythrocyte indices	MDM2	targetBased	0.163113198045062	8	207811	220
uHTS Luminescent assay for identification of inhibitors of Sentrin-specific protease 7 (SENP7)	erythrocyte indices	SENP7	targetBased	0.15153501619351	10	331670	4902
HTS for Estrogen Receptor-beta Coactivator Binding inhibitors	erythrocyte indices	ESR2_inhibitors	targetBased	0.18264407510342	4	86095	1114
qHTS Assay for Identifying a Potential Treatment of Ataxia-Telangiectasia	erythrocyte indices	ATM_modulators	targetBased	0.156253843487605	16	322361	619
Fluorescence-based biochemical high throughput primary assay to identify inhibitors of phospholipase C isozymes (PLC-beta3).	erythrocyte indices	PLCB3	targetBased	0.133259531457079	8	369953	662
Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2	erythrocyte indices	THRB	targetBased	0.183291513434387	27	276265	806
uHTS identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay	hematological measurement	UBE2N	targetBased	0.177557838681355	27	330393	1538
Thrombin 1536 HTS	hematological measurement	F2_modulation	targetBased	0.153298490638028	13	217233	557
qHTS Assay for the Inhibitors of L3MBTL1	hematological measurement	L3MBTL1	targetBased	0.115085061377337	5	225309	1492
qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding	hematological measurement	MAPT	pathwayBased	0.160576521347521	62	267412	5703
qHTS Assay for Tau Filament Binding	hematological measurement	MAPT	targetBased	0.160576521347521	62	69668	1391
qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization	hematological measurement	MAPT	pathwayBased	0.160576521347521	62	271402	1048
AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of microphthalmia-associated transcription factor (MITF)	hematological measurement	MITF inhibitors	targetBased	0.204895436284748	24	642362	5830
MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Inhibitor_SinglePoint_HTS_Activity	hematological measurement	MITF	targetBased	0.204895436284748	24	331360	2760
uHTS Fluorescent assay for identification of inhibitors of hexokinase domain containing I (HKDC1)	erythrocyte indices	HKDC1	targetBased	0.180814522547264	20	340696	540
Dyrk1 A HTS Measured in Biochemical System Using Plate Reader - 2124-01_Inhibitor_SinglePoint_HTS_Activity	erythrocyte indices	DYRK1A_inhibitors	targetBased	0.11310793032075	4	310014	1321
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb via a fluorescence resonance energy transfer (FRET) assay.	erythrocyte indices	RUNX1	targetBased	0.107539227435466	15	215667	993
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay.	erythrocyte indices	RUNX1	targetBased	0.107539227435466	15	218234	1620
Inhibitors of USP1/UAF1: Primary Screen	erythrocyte indices	USP1	targetBased	0.126012446199164	10	389569	904
Primary biochemical high-throughput screening assay to measure P97 ATPase inhibition	erythrocyte indices	VCP	targetBased	0.134802034350887	6	217959	923
Primary cell-based high throughput screening assay to measure STAT3 activation	erythrocyte indices	STAT3	pathwayBased	0.139682355782146	6	194666	1772
Primary cell-based high throughput screening assay to measure STAT3 inhibition	erythrocyte indices	STAT3	pathwayBased	0.139682355782146	6	194666	1722
qHTS Assay for Activators of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease	erythrocyte indices	GAA	targetBased	0.120014820841895	8	199169	715
qHTS Assay for Inhibitors and Activators of Human alpha-Glucosidase Cleavage of Glycogen	erythrocyte indices	GAA_inhibitors	targetBased	0.120014820841895	8	302297	1165
Inhibition of the MLL-AF4-AF9 Interaction in Pediatric Leukemia Measured in Biochemical System Using Plate Reader - 2160-01_Inhibitor_SinglePoint_HTS_Activity	erythrocyte indices	MLLT3	targetBased	0.105201461802422	8	344459	1627
Inhibitors of Cav3 T-type Calcium Channels: Primary Screen	hematological measurement	CACNA1H_inhibitors	targetBased	0.128335057063608	4	104728	4230
Alphascreen assay for small molecules abrogating mHTT-CaM Interaction	hematological measurement	HTT	targetBased	0.169420779783663	17	189882	6790
Primary qHTS for Identification of Small Molecule Inhibitors of Huntingtin Promoter Activity	hematological measurement	HTT	targetBased	0.169420779783663	17	48068	449
qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Aggregate Formation (GFP)	hematological measurement	HTT	targetBased	0.169420779783663	17	220571	2380
qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Cytoprotection (ATP)	hematological measurement	HTT	targetBased	0.169420779783663	17	223611	305
uHTS for identification of Inhibitors of Mdm2/MdmX interaction in luminescent format.	hematological measurement	MDM4	targetBased	0.129009951299108	7	331671	10022
Primary qHTS for Inhibitors of ATXN expression	hematological measurement	ATXN2_repressors	targetBased	0.160640208741895	118	358434	2554
qHTS screen for small molecules that induce genotoxicity in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1	erythrocyte indices	ATAD5_inhibitors	targetBased	0.141229800613081	6	330109	4174
qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1	erythrocyte indices	ATAD5_inhibitors	targetBased	0.141229800613081	6	330107	7652
uHTS identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay	erythrocyte indices	UBE2N	targetBased	0.149939193019733	12	330393	1538
AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of microphthalmia-associated transcription factor (MITF)	erythrocyte indices	MITF inhibitors	targetBased	0.186053397357697	6	642362	5830
MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Inhibitor_SinglePoint_HTS_Activity	erythrocyte indices	MITF	targetBased	0.186053397357697	6	331360	2760
Primary qHTS for Inhibitors of ATXN expression	erythrocyte indices	ATXN2_repressors	targetBased	0.124406782408209	11	358434	2554
Primary HTS Assay for S1P3 Antagonists	hematological measurement	S1PR3	targetBased	0.203193039985341	72	169141	462
qHTS for Inhibitors of Vif-A3G Interactions: qHTS	hematological measurement	APOBEC3G_inhibitors	targetBased	0.111904110807494	20	402348	311
uHTS identification of APOBEC3G DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay	hematological measurement	APOBEC3G_inhibitors	targetBased	0.111904110807494	20	331753	931
Primary screen for compounds that activate Insulin promoter activity in TRM-6 cells	hematological measurement	INS	targetBased	0.149666397299191	9	128695	1039
Primary screen for compounds that inhibit Insulin promoter activity in TRM-6 cells	hematological measurement	INS	targetBased	0.149666397299191	9	127961	1153
Primary Cell-Based High-Throughput Screening to Identify Agonists of the Sphingosine 1-phosphate receptor 2 (S1P2)	hematological measurement	S1PR2	targetBased	0.230924765830876	47	96879	447
Primary Cell-Based High-Throughput Screening to Identify Antagonists of the Sphingosine 1-phosphate receptor 2 (S1P2)	hematological measurement	S1PR2	targetBased	0.230924765830876	47	96879	207
Primary HTS Assay for S1P3 Antagonists	erythrocyte indices	S1PR3	targetBased	0.154034292111585	10	169141	462
FRET-based HTS for detection of RAD52 Inhibitors Measured in Biochemical System Using Plate Reader - 7018-01_Inhibitor_SinglePoint_HTS_Activity_Set2	leukocyte count	RAD52	targetBased	0.127210183593114	7	352074	1608
High Content Assay for Compounds that inhibit the Assembly of the Perinucleolar Compartment	leukocyte count	PTBP1	targetBased	0.140014669732189	6	139718	4338
Fluorescence-based primary biochemical high throughput screening assay to identify inhibitors of Protein Phosphatase 5 (PP5).	leukocyte count	PPP5C	targetBased	0.135024026514046	7	314999	564
Primary Cell-based High Throughput Screening assay for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA)	leukocyte count	RORA	pathwayBased	0.167661383357954	7	64908	979
Primary Cell-based High Throughput Screening assay for inhibitors of the Retinoic Acid Receptor-related orphan receptor A (RORA)	leukocyte count	RORA	pathwayBased	0.167661383357954	7	64908	278
HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Inhibitor_SinglePoint_HTS_Activity	leukocyte count	SCARB1	targetBased	0.171308118090153	5	319204	3065
HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Activator_SinglePoint_HTS_Activity	leukocyte count	SCARB1	targetBased	0.171308118090153	5	316970	306
Primary cell-based high throughput screening assay to identify inhibitors of kruppel-like factor 5 (KLF5)	leukocyte count	KLF5	targetBased	0.148154548846255	6	290726	671
Identification of Molecular Probes that Activate MRP-1	leukocyte count	ABCC1_activators	targetBased	0.17846999350391	5	138717	842
Luminescence-based primary cell-based high throughput screening assay to identify activators of the Aryl Hydrocarbon Receptor (AHR)	leukocyte count	AHR_activators	targetBased	0.162669297878254	9	324747	7988
Fluorescence Biochemical Primary HTS to Identify Inhibitors of GASC-1 Activity	leukocyte count	KDM4C	targetBased	0.112867260193194	4	326066	228
qHTS of IL-2 Activators	leukocyte count	IL2	targetBased	0.117691976627195	9	364617	238
uHTS identification of small molecule antagonists of the CCR6 receptor via a luminescent beta-arrestin assay	leukocyte count	CCR6_antagonists	targetBased	0.159824719646003	4	340696	1654
Small-molecule inhibitors of ST2 (IL1RL1)	leukocyte count	IL1RL1	targetBased	0.183219425227019	24	75924	1804
Luminescence-based cell-based high throughput primary screening assay to identify agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3)	hematological measurement	NR2E3	targetBased	0.100968271653302	8	362026	1281
TR-FRET-based primary biochemical high throughput screening assay to identify agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3).	hematological measurement	NR2E3	targetBased	0.100968271653302	8	314998	380
HTS Assay for Peg3 Promoter Inhibitors	hemoglobin measurement	PPP1R15A	targetBased	0.150134111895518	7	359244	6145
uHTS identification of Caspase-8 TRAIL sensitizers in a luminesence assay	leukocyte count	TNFRSF10B	targetBased	0.138819471902896	8	363840	3764
uHTS for the identification of compounds that potentiate TRAIL-induced apoptosis of cancer cells	leukocyte count	TNFSF10	targetBased	0.17039072154522	6	217035	883
Primary cell-based high-throughput screening assay for identification of compounds that inhibit/block inward-rectifying potassium ion channel Kir2.1	leukocyte count	KCNJ2	targetBased	0.172498000749499	7	305610	2592
MLPCN SirT-5 Measured in Biochemical System Using Imaging - 7044-01_Inhibitor_SinglePoint_HTS_Activity_Set5	leukocyte count	SIRT5	targetBased	0.113529629551725	5	323507	3752
Primary cell-based high-throughput screening for identification of compounds that inhibit/block calcium-activated chloride channels (TMEM16A)	leukocyte count	ANO1_inhibitors	targetBased	0.133363177956471	6	306502	3633
Primary cell-based high-throughput screening for identification of compounds that activate/potentiate calcium-activated chloride channels (TMEM16A)	leukocyte count	ANO1_activators	targetBased	0.133363177956471	6	335180	1022
Flow Cytometric HTS Screen for inhibitors of the ABC transporter ABCB6 for MLPCN Compound Set	hemoglobin measurement	ABCB6_inhibitors	targetBased	0.13568904451674	6	362098	692
uHTS Luminescent assay for identification of inhibitors of Sentrin-specific protease 7 (SENP7)	leukocyte count	SENP7	targetBased	0.136527472426125	5	331670	4902
Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2	leukocyte count	THRB	targetBased	0.172559456679052	5	276265	806
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb via a fluorescence resonance energy transfer (FRET) assay.	leukocyte count	RUNX1	targetBased	0.117129394030097	36	215667	993
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay.	leukocyte count	RUNX1	targetBased	0.117129394030097	36	218234	1620
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of Protein Arginine Deiminase 4 (PAD4) (1536 HTS)	leukocyte count	PADI4	targetBased	0.163222401016216	5	326022	1334
Primary cell-based high-throughput screening assay for identification of compounds that inhibit KCNQ1 potassium channels	glycoprotein measurement	KCNQ1	targetBased	0.160628534937412	5	305610	3878
Primary cell-based high-throughput screening assay for identification of compounds that potentiate/activate KCNQ1 potassium channels	glycoprotein measurement	KCNQ1	targetBased	0.160628534937412	5	305610	1082
Primary Cell-based High Throughput Screening assay for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA)	glycoprotein measurement	RORA	pathwayBased	0.115100631884613	4	64908	979
Primary Cell-based High Throughput Screening assay for inhibitors of the Retinoic Acid Receptor-related orphan receptor A (RORA)	glycoprotein measurement	RORA	pathwayBased	0.115100631884613	4	64908	278
Nrf2 qHTS screen for inhibitors	glycoprotein measurement	nrf2Inhibitors	targetBased	0.167680652324781	4	360873	7438
qHTS of Nrf2 Activators	glycoprotein measurement	Nrf2 activators	pathwayBased	0.167680652324781	4	403871	1243
uHTS for the identification of compounds that potentiate TRAIL-induced apoptosis of cancer cells	glycoprotein measurement	TNFSF10	targetBased	0.175582563529933	10	217035	883
Fluorescence-based biochemical high throughput primary assay to identify inhibitors of phospholipase C isozymes (PLC-gamma1).	glycoprotein measurement	PLCG1	targetBased	0.111189690965076	4	369953	3123
Primary biochemical high-throughput screening assay to measure P97 ATPase inhibition	leukocyte count	VCP	targetBased	0.11763715998554	5	217959	923
Primary biochemical high throughput screening assay to identify inhibitors of BCL2-related protein, long isoform (BCLXL).	leukocyte count	BCL2L1_modulators	targetBased	0.149082293367432	9	314998	2199
qHTS screen for small molecules that induce genotoxicity in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1	leukocyte count	ATAD5_inhibitors	targetBased	0.125809387475244	6	330109	4174
qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1	leukocyte count	ATAD5_inhibitors	targetBased	0.125809387475244	6	330107	7652
Fluorescence-based primary biochemical high throughput screening assay to identify inhibitors of human diacylglycerol lipase, beta (DAGLB)	hemoglobin measurement	DAGLB_inhibitors	targetBased	0.149352547643408	7	343468	202
qHTS Assay for Activators of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease	hemoglobin measurement	GAA	targetBased	0.109058276901556	5	199169	715
qHTS Assay for Inhibitors and Activators of Human alpha-Glucosidase Cleavage of Glycogen	hemoglobin measurement	GAA_inhibitors	targetBased	0.109058276901556	5	302297	1165
Inhibitors of Cav3 T-type Calcium Channels: Primary Screen	leukocyte count	CACNA1H_inhibitors	targetBased	0.127929346517776	4	104728	4230
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	glycoprotein measurement	PPARG	targetBased	0.17313032691313	13	99314	335
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	glycoprotein measurement	PPARG	targetBased	0.17313032691313	13	196176	782
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	glycoprotein measurement	PPARG	targetBased	0.17313032691313	13	99314	390
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	glycoprotein measurement	PPARG	targetBased	0.17313032691313	13	196177	811
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	glycoprotein measurement	PPARG	targetBased	0.17313032691313	13	196176	670
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	glycoprotein measurement	PPARG	targetBased	0.17313032691313	13	196177	519
Luminescence cell-based high throughput primary assay to identify inhibitors of TEAD-YAP interaction.	glycoprotein measurement	YAP1	targetBased	0.170662009515076	4	639428	9218
qHTS assay for re-activators of p53 using a Luc reporter	glycoprotein measurement	TP53	pathwayBased	0.102164716219836	64	321427	201
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Nonpermissive Temperature	glycoprotein measurement	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.102164716219836	64	54509	528
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Permissive Temperature	glycoprotein measurement	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.102164716219836	64	54513	338
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature	glycoprotein measurement	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.102164716219836	64	125394	1890
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Permissive Temperature	glycoprotein measurement	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.102164716219836	64	124022	1156
HTS Assay for Inhibitors of Akt Phophorylation: Primary Screen	glycoprotein measurement	AKT1_inhibitors	targetBased	0.10953182332247	4	356517	1139
Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2	glycoprotein measurement	THRB	targetBased	0.177770135701417	4	276265	806
Luminescence Cell-Based Primary HTS to Identify Inhibitors of A1 Apoptosis.	glycoprotein measurement	BCL2L11_inhibitors	targetBased	0.169208744945454	10	325630	216
uHTS Fluorescent assay for identification of inhibitors of hexokinase domain containing I (HKDC1)	glycoprotein measurement	HKDC1	targetBased	0.158294526306224	12	340696	540
uHTS identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay	hemoglobin measurement	UBE2N	targetBased	0.160965592657621	7	330393	1538
uHTS absorbance assay for the identification of compounds that inhibit PHOSPHO1	glycoprotein measurement	PHOSPHO1	targetBased	0.152555700871901	13	288321	3164
Luminescence-based cell-based primary high throughput screening assay to identify inhibitors of COUP-TFII (NR2F2)	glycoprotein measurement	NR2F2	targetBased	0.154850748366129	9	369953	2602
Primary HTS Assay for S1P3 Antagonists	hemoglobin measurement	S1PR3	targetBased	0.166464234646689	12	169141	462
Primary screen for compounds that activate Insulin promoter activity in TRM-6 cells	glycoprotein measurement	INS	targetBased	0.146240867267761	5	128695	1039
Primary screen for compounds that inhibit Insulin promoter activity in TRM-6 cells	glycoprotein measurement	INS	targetBased	0.146240867267761	5	127961	1153
FRET-based HTS for detection of RAD52 Inhibitors Measured in Biochemical System Using Plate Reader - 7018-01_Inhibitor_SinglePoint_HTS_Activity_Set2	erythrocyte indices	RAD52	targetBased	0.14863617976312	5	352074	1608
HTS Assay for Peg3 Promoter Inhibitors	erythrocyte indices	PPP1R15A	targetBased	0.144881433709427	5	359244	6145
Identification of Molecular Probes that Activate MRP-1	erythrocyte indices	ABCC1_activators	targetBased	0.184341075875016	11	138717	842
qHTS Assay for NPC1 Promoter Activators	erythrocyte indices	NPC1	pathwayBased	0.165269916985511	11	320682	7575
Inhibitors of CDC25B-CDK2/CyclinA interaction	erythrocyte indices	Inhibitors of CDC25B-CDK2/CyclinA interaction	targetBased	0.167057912944654	16	93798	679
Luminescence Cell-Based Primary HTS to Identify Inhibitors of A1 Apoptosis.	erythrocyte indices	BCL2L11_inhibitors	targetBased	0.18131963739853	64	325630	216
uHTS Luminescent assay for identification of inhibitors of NALP3 in yeast	erythrocyte indices	NLRP3	targetBased	0.151524390547044	4	330392	1295
Primary biochemical high-throughput screening assay for inhibitors of Focal Adhesion Kinase (FAK)	erythrocyte indices	PTK2	targetBased	0.142586695487658	4	96879	811
Inhibitors of the vitamin D receptor (VDR): qHTS	leukocyte count	VDR	targetBased	0.140256122866946	5	394050	3624
Primary cell-based high throughput screening assay to measure STAT1 activation	leukocyte count	STAT1 activation	pathwayBased	0.165597230755596	5	195980	5134
Primary cell-based high throughput screening assay to measure STAT1 inhibition	leukocyte count	STAT1	targetBased	0.165597230755596	5	195980	695
HTS of Smad transcription factor inhibitors	leukocyte count	SMAD3	targetBased	0.188713301145527	19	88033	251
uHTS identification of small molecule antagonists of the EBI2 receptor via a luminescent beta-arrestin assay	leukocyte count	GPR183	targetBased	0.121492857051512	13	363840	2946
Primary cell-based high throughput screening assay to identify inhibitors of kruppel-like factor 5 (KLF5)	hematological measurement	KLF5	targetBased	0.149044136662509	7	290726	671
Luminescence-based cell-based primary high throughput screening assay to identify inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3)	hematological measurement	NCOA3	targetBased	0.143139253667258	5	359207	620
Primary biochemical high-throughput screening assay for inhibitors of Rho kinase 2 (Rhok2)	hematological measurement	ROCK2	targetBased	0.156242465026251	10	59788	212
E3 Ligase HTS_1536	hematological measurement	MDM2	targetBased	0.168499632298348	19	207811	220
Luminescence cell-based high throughput primary assay to identify inhibitors of TEAD-YAP interaction.	hematological measurement	YAP1	targetBased	0.177981758287764	19	639428	9218
USP8 deubiquitinase inhibition: Primary qHTS	hematological measurement	USP8	targetBased	0.146681495473618	9	47480	2010
Primary HTS assay for chemical inhibitors of TNF alpha stimulated VCAM1 expression	hematological measurement	VCAM1_expression	targetBased	0.185008168739799	45	94498	457
MLPCN ERAP1 Measured in Biochemical System Using Plate Reader - 7016-01_Inhibitor_SinglePoint_HTS_Activity	hematological measurement	ERAP1_inhibitors	targetBased	0.165187437675653	10	335777	499
qHTS screen for small molecules that induce genotoxicity in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1	hematological measurement	ATAD5_inhibitors	targetBased	0.14971384536316	22	330109	4174
qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1	hematological measurement	ATAD5_inhibitors	targetBased	0.14971384536316	22	330107	7652
HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Inhibitor_SinglePoint_HTS_Activity	hemoglobin measurement	SCARB1	targetBased	0.197228074557595	6	319204	3065
HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Activator_SinglePoint_HTS_Activity	hemoglobin measurement	SCARB1	targetBased	0.197228074557595	6	316970	306
Primary HTS and Confirmation Assays for S1P1 Agonists and Agonism Potentiators	neutrophil count	S1PR1	targetBased	0.165448354599344	5	55710	315
FRET-based HTS for detection of RAD52 Inhibitors Measured in Biochemical System Using Plate Reader - 7018-01_Inhibitor_SinglePoint_HTS_Activity_Set2	complete blood cell count	RAD52	targetBased	0.128083975201518	8	352074	1608
HTS for developing T Cell Immune Modulators	complete blood cell count	ITGAL	targetBased	0.167859877040972	27	326271	221
Identification of agents that induce E-selectin on human endothelial cells Measured in Cell-Based System Using Imaging - 2152-01_Activator_SinglePoint_HTS_Activity	complete blood cell count	SELE	targetBased	0.106686147852546	6	257988	963
Primary HTS assay for chemical inhibitors of TNF alpha stimulated E-Selectin expression	complete blood cell count	E-selectinExpression	targetBased	0.106686147852546	6	118096	843
High Content Assay for Compounds that inhibit the Assembly of the Perinucleolar Compartment	complete blood cell count	PTBP1	targetBased	0.145407733645207	9	139718	4338
Fluorescence-based primary biochemical high throughput screening assay to identify inhibitors of Protein Phosphatase 5 (PP5).	complete blood cell count	PPP5C	targetBased	0.135818879224181	8	314999	564
Primary Cell-based High Throughput Screening assay for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA)	complete blood cell count	RORA	pathwayBased	0.169010231120403	9	64908	979
Primary Cell-based High Throughput Screening assay for inhibitors of the Retinoic Acid Receptor-related orphan receptor A (RORA)	complete blood cell count	RORA	pathwayBased	0.169010231120403	9	64908	278
HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Inhibitor_SinglePoint_HTS_Activity	complete blood cell count	SCARB1	targetBased	0.171308118090153	5	319204	3065
HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Activator_SinglePoint_HTS_Activity	complete blood cell count	SCARB1	targetBased	0.171308118090153	5	316970	306
HTS to identify compounds that promote myeloid differentiation with MLPCN compound set	complete blood cell count	HOXA9	pathwayBased	0.15270080983704	17	358556	3721
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	complete blood cell count	JAK2	targetBased	0.262808576915833	57	217959	2390
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of the interaction of the Ras and Rab interactor 1 protein (Rin1) and the c-abl oncogene 1, non-receptor tyrosine kinase (Abl)	complete blood cell count	ABL1_interaction	targetBased	0.140407631861701	7	359207	1432
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	coagulation factor measurement	FGB_inhibitors	targetBased	0.185754204231447	10	369953	760
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	coagulation factor measurement	FGB_inhibitors	targetBased	0.185754204231447	10	369953	498
Identification of CBX7 inhibitors - Primary Alpha Screen	complete blood cell count	Chromobox protein homolog 7 inhibitors	targetBased	0.165216462100591	15	64999	724
qHTS for Inhibitors of Polymerase Iota	complete blood cell count	POLI	targetBased	0.12334414459832	18	386063	3989
qHTS Assay for Inhibitors of the CtBP/E1A Interaction	complete blood cell count	RBBP8	targetBased	0.13818395374801	9	335214	1652
Primary cell-based high throughput screening assay to identify inhibitors of kruppel-like factor 5 (KLF5)	complete blood cell count	KLF5	targetBased	0.148154548846255	6	290726	671
Identification of Molecular Probes that Activate MRP-1	complete blood cell count	ABCC1_activators	targetBased	0.17846999350391	5	138717	842
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype	complete blood cell count	RAB2A	targetBased	0.156257439695257	9	194628	365
qHTS for Inhibitors of TGF-b	complete blood cell count	TGFB1	pathwayBased	0.107099139700351	4	403345	4970
Luminescence-based primary cell-based high throughput screening assay to identify activators of the Aryl Hydrocarbon Receptor (AHR)	complete blood cell count	AHR_activators	targetBased	0.16269470052564	9	324747	7988
Fluorescence Biochemical Primary HTS to Identify Inhibitors of GASC-1 Activity	complete blood cell count	KDM4C	targetBased	0.125281357277486	5	326066	228
High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Primary Screen	complete blood cell count	NFKB1	pathwayBased	0.188877493803406	30	193265	3100
uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay	complete blood cell count	NFKB1	pathwayBased	0.188877493803406	30	359244	3094
Fluorescence-based biochemical primary high throughput screening assay to identify activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF)	complete blood cell count	TNNI3	targetBased	0.13181073626143	7	335239	801
Fluorescence-based biochemical primary high throughput screening assay to identify inhibitors of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF)	complete blood cell count	TNNI3	targetBased	0.13181073626143	7	335238	390
Primary cell-based high-throughput screening for identification of compounds that inhibit/block calcium-activated chloride channels (TMEM16A)	complete blood cell count	ANO1_inhibitors	targetBased	0.133363177956471	6	306502	3633
Primary cell-based high-throughput screening for identification of compounds that activate/potentiate calcium-activated chloride channels (TMEM16A)	complete blood cell count	ANO1_activators	targetBased	0.133363177956471	6	335180	1022
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	complete blood cell count	PPARG	targetBased	0.183379707206353	41	99314	335
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	complete blood cell count	PPARG	targetBased	0.183379707206353	41	196176	782
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	complete blood cell count	PPARG	targetBased	0.183379707206353	41	99314	390
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	complete blood cell count	PPARG	targetBased	0.183379707206353	41	196177	811
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	complete blood cell count	PPARG	targetBased	0.183379707206353	41	196176	670
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	complete blood cell count	PPARG	targetBased	0.183379707206353	41	196177	519
High throughput screening of activators of transient receptor potential cation channel C6 (TRPC6)	complete blood cell count	TRPC6	targetBased	0.182041801829643	6	305610	382
High throughput screening of inhibitors of transient receptor potential cation channel C6 (TRPC6)	complete blood cell count	TRPC6	targetBased	0.182041801829643	6	305610	3253
Luminescence cell-based high throughput primary assay to identify inhibitors of TEAD-YAP interaction.	complete blood cell count	YAP1	targetBased	0.151981521996798	4	639428	9218
uHTS Luminescent assay for identification of inhibitors of Sentrin-specific protease 7 (SENP7)	complete blood cell count	SENP7	targetBased	0.149180005002839	10	331670	4902
USP8 deubiquitinase inhibition: Primary qHTS	complete blood cell count	USP8	targetBased	0.135108462788375	8	47480	2010
HTS for Estrogen Receptor-beta Coactivator Binding inhibitors	complete blood cell count	ESR2_inhibitors	targetBased	0.179656555593616	5	86095	1114
Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bfl-1	complete blood cell count	BCL2A1_modulators	targetBased	0.170484079946485	30	194826	237
Luminescence-based cell-based primary high throughput screening assay to identify inhibitors of the Steroid Receptor Coactivator 2 (SRC2; NCOA2)	complete blood cell count	NCOA2	targetBased	0.135541058690664	4	368927	620
qHTS Assay for NPC1 Promoter Activators	complete blood cell count	NPC1	pathwayBased	0.190693067500584	20	320682	7575
uHTS identification of small molecule antagonists of the CCR6 receptor via a luminescent beta-arrestin assay	complete blood cell count	CCR6_antagonists	targetBased	0.159824719646003	4	340696	1654
HTS for Identification of VLA-4 Allosteric Modulators from MLPCN library	complete blood cell count	ITGA4	targetBased	0.206549382942402	66	326888	645
Primary cell-based high throughput screening assay to measure STAT1 activation	complete blood cell count	STAT1 activation	pathwayBased	0.16577060694288	6	195980	5134
Primary cell-based high throughput screening assay to measure STAT1 inhibition	complete blood cell count	STAT1	targetBased	0.16577060694288	6	195980	695
Small-molecule inhibitors of ST2 (IL1RL1)	complete blood cell count	IL1RL1	targetBased	0.183219425227019	24	75924	1804
uHTS identification of HIF-2a Inhibitors in a luminesence assay	complete blood cell count	HIF-2a_inhibitors	targetBased	0.150290668487629	20	363840	2624
uHTS identification of Caspase-8 TRAIL sensitizers in a luminesence assay	complete blood cell count	TNFRSF10B	targetBased	0.152412650298517	10	363840	3764
Antagonist identification of Pyk2 oligomerization: high-throughput screening cellular assay	complete blood cell count	Pyk2Ã‚Â	targetBased	0.127044817917774	10	98749	818
uHTS for the identification of compounds that potentiate TRAIL-induced apoptosis of cancer cells	complete blood cell count	TNFSF10	targetBased	0.175006213820944	10	217035	883
qHTS Assay for Inhibitors of BAZ2B	complete blood cell count	BAZ2B_modulators	targetBased	0.162246816689748	15	356826	15709
Primary cell-based high-throughput screening assay for identification of compounds that inhibit/block inward-rectifying potassium ion channel Kir2.1	complete blood cell count	KCNJ2	targetBased	0.172498000749499	7	305610	2592
MLPCN SirT-5 Measured in Biochemical System Using Imaging - 7044-01_Inhibitor_SinglePoint_HTS_Activity_Set5	complete blood cell count	SIRT5	targetBased	0.130162703891683	5	323507	3752
HTS for PAX8 inhibitors using PAX8 luciferase reporter gene assay in RMG-I cells Measured in Cell-Based System Using Plate Reader - 7054-01_Inhibitor_SinglePoint_HTS_Activity	complete blood cell count	PAX8	targetBased	0.143612269113485	9	353950	4145
Primary Cell-Based Assay to Identify Agonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	complete blood cell count	S1PR4	targetBased	0.256184169311542	53	217959	771
Primary Cell-Based Assay to Identify Antagonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	complete blood cell count	S1PR4	targetBased	0.256184169311542	53	217959	569
HTS Assay for Inhibitors of Akt Phophorylation: Primary Screen	complete blood cell count	AKT1_inhibitors	targetBased	0.104613474474831	5	356517	1139
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of myeloid cell leukemia sequence 1 (MCL1) interactions with BIM-BH3 peptide.	complete blood cell count	MCL1	targetBased	0.105281299353101	27	314998	2139
uHTS of Mcl-1/Bid interaction inhibitors	complete blood cell count	MCL1	targetBased	0.105281299353101	27	218602	2129
uHTS of Mcl-1/Noxa interaction inhibitors	complete blood cell count	MCL1	targetBased	0.105281299353101	27	217330	3334
Inhibitors of CDC25B-CDK2/CyclinA interaction	complete blood cell count	Inhibitors of CDC25B-CDK2/CyclinA interaction	targetBased	0.121551031414743	5	93798	679
Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2	complete blood cell count	THRB	targetBased	0.178499145957374	10	276265	806
uHTS Fluorescent assay for identification of inhibitors of hexokinase domain containing I (HKDC1)	complete blood cell count	HKDC1	targetBased	0.171579086038117	15	340696	540
Dyrk1 A HTS Measured in Biochemical System Using Plate Reader - 2124-01_Inhibitor_SinglePoint_HTS_Activity	complete blood cell count	DYRK1A_inhibitors	targetBased	0.153952503015751	15	310014	1321
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb via a fluorescence resonance energy transfer (FRET) assay.	complete blood cell count	RUNX1	targetBased	0.163643800231703	55	215667	993
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay.	complete blood cell count	RUNX1	targetBased	0.163643800231703	55	218234	1620
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of Protein Arginine Deiminase 4 (PAD4) (1536 HTS)	complete blood cell count	PADI4	targetBased	0.163222401016216	5	326022	1334
Primary HTS assay for chemical inhibitors of TNF alpha stimulated VCAM1 expression	complete blood cell count	VCAM1_expression	targetBased	0.181778481449906	25	94498	457
uHTS Luminescent assay for identification of inhibitors of NALP3 in yeast	complete blood cell count	NLRP3	targetBased	0.20348002413496	27	330392	1295
MLPCN ERAP1 Measured in Biochemical System Using Plate Reader - 7016-01_Inhibitor_SinglePoint_HTS_Activity	complete blood cell count	ERAP1_inhibitors	targetBased	0.145458674345435	6	335777	499
Fluorescence-based primary biochemical high throughput screening assay to identify inhibitors of human diacylglycerol lipase, beta (DAGLB)	complete blood cell count	DAGLB_inhibitors	targetBased	0.172089477499121	25	343468	202
Primary biochemical high-throughput screening assay to measure P97 ATPase inhibition	complete blood cell count	VCP	targetBased	0.143907503497986	8	217959	923
HTS for Beta-2AR agonists via FAP method	complete blood cell count	ADRB2_activators	targetBased	0.185009599074487	29	339297	1446
uHTS identification of small molecule antagonists of the EBI2 receptor via a luminescent beta-arrestin assay	complete blood cell count	GPR183	targetBased	0.121492857051512	13	363840	2946
Primary HTS and Confirmation Assays for S1P1 Agonists and Agonism Potentiators	complete blood cell count	S1PR1	targetBased	0.196345255376437	41	55710	315
Primary biochemical high throughput screening assay to identify inhibitors of BCL2-related protein, long isoform (BCLXL).	complete blood cell count	BCL2L1_modulators	targetBased	0.176713890222121	21	314998	2199
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	complete blood cell count	FGB_inhibitors	targetBased	0.189061503167718	5	369953	760
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	complete blood cell count	FGB_inhibitors	targetBased	0.189061503167718	5	369953	498
qHTS screen for small molecules that induce genotoxicity in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1	complete blood cell count	ATAD5_inhibitors	targetBased	0.128197735000048	7	330109	4174
qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1	complete blood cell count	ATAD5_inhibitors	targetBased	0.128197735000048	7	330107	7652
uHTS identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay	complete blood cell count	UBE2N	targetBased	0.156897794087403	6	330393	1538
AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of microphthalmia-associated transcription factor (MITF)	complete blood cell count	MITF inhibitors	targetBased	0.181561752979958	8	642362	5830
MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Inhibitor_SinglePoint_HTS_Activity	complete blood cell count	MITF	targetBased	0.181561752979958	8	331360	2760
Inhibitors of Cav3 T-type Calcium Channels: Primary Screen	complete blood cell count	CACNA1H_inhibitors	targetBased	0.127929346517776	4	104728	4230
Alphascreen assay for small molecules abrogating mHTT-CaM Interaction	complete blood cell count	HTT	targetBased	0.155182555688012	10	189882	6790
Primary qHTS for Identification of Small Molecule Inhibitors of Huntingtin Promoter Activity	complete blood cell count	HTT	targetBased	0.155182555688012	10	48068	449
qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Aggregate Formation (GFP)	complete blood cell count	HTT	targetBased	0.155182555688012	10	220571	2380
qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Cytoprotection (ATP)	complete blood cell count	HTT	targetBased	0.155182555688012	10	223611	305
Primary qHTS for Inhibitors of ATXN expression	complete blood cell count	ATXN2_repressors	targetBased	0.152965248085757	63	358434	2554
Primary HTS Assay for S1P3 Antagonists	complete blood cell count	S1PR3	targetBased	0.202169376470243	40	169141	462
qHTS for Inhibitors of Vif-A3G Interactions: qHTS	complete blood cell count	APOBEC3G_inhibitors	targetBased	0.111561354682285	13	402348	311
uHTS identification of APOBEC3G DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay	complete blood cell count	APOBEC3G_inhibitors	targetBased	0.111561354682285	13	331753	931
Primary Cell-Based High-Throughput Screening to Identify Agonists of the Sphingosine 1-phosphate receptor 2 (S1P2)	complete blood cell count	S1PR2	targetBased	0.211783072982781	24	96879	447
Primary Cell-Based High-Throughput Screening to Identify Antagonists of the Sphingosine 1-phosphate receptor 2 (S1P2)	complete blood cell count	S1PR2	targetBased	0.211783072982781	24	96879	207
Inhibitors of the vitamin D receptor (VDR): qHTS	complete blood cell count	VDR	targetBased	0.14065950062086	7	394050	3624
Toxoplasma gondii inhibition HTS in the presence of IFN-y	complete blood cell count	IFNG	targetBased	0.171818445404274	8	67275	2509
qHTS for Inhibitors of Glutaminase (GLS)	complete blood cell count	GLS	targetBased	0.151240903300174	4	405291	844
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of 5-meCpG-binding domain protein 2 (MBD2)-DBD binding to methylated oligonucleotide	complete blood cell count	MBD2	targetBased	0.140137880985615	14	369953	1149
qHTS for Activators of Integrin-Mediated Alleviation for Muscular Dystrophy	complete blood cell count	CGA_integrin_activators	targetBased	0.127009403052068	16	345855	222
Luminescence Cell-Based Primary HTS to Identify Inhibitors of A1 Apoptosis.	complete blood cell count	BCL2L11_inhibitors	targetBased	0.18438616773519	88	325630	216
HTS identification of compounds inhibiting the binding of CD11b/CD18 to fibrinogen via a luminescence assay.	complete blood cell count	ITGB2	targetBased	0.154704961285135	5	92518	501
qHTS Assay for Inhibitors of 15-hLO (15-human lipoxygenase)	complete blood cell count	ALOX15_inhibitors	targetBased	0.248942083932216	29	73174	1034
Luminescence-based cell-based primary high throughput screening assay to identify biased ligands of the melanocortin 4 receptor (MC4R): agonists of MC4R	complete blood cell count	MC4R	targetBased	0.129684813965177	4	356160	3470
TRFRET-based cell-based primary high throughput screening assay to identify biased ligands of the melanocortin 4 receptor (MC4R): antagonists of MC4R	complete blood cell count	MC4R	targetBased	0.129684813965177	4	356160	1703
HTS of Smad transcription factor inhibitors	complete blood cell count	SMAD3	targetBased	0.188818064036502	22	88033	251
qHTS Assay for Activators of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease	complete blood cell count	GAA	targetBased	0.134580130682997	4	199169	715
qHTS Assay for Inhibitors and Activators of Human alpha-Glucosidase Cleavage of Glycogen	complete blood cell count	GAA_inhibitors	targetBased	0.134580130682997	4	302297	1165
Thrombin 1536 HTS	complete blood cell count	F2_modulation	targetBased	0.150125959161881	4	217233	557
Primary cell-based high-throughput screening assay for identification of compounds that inhibit KCNQ1 potassium channels	platelet measurement	KCNQ1	targetBased	0.146009129882972	7	305610	3878
Primary cell-based high-throughput screening assay for identification of compounds that potentiate/activate KCNQ1 potassium channels	platelet measurement	KCNQ1	targetBased	0.146009129882972	7	305610	1082
HTS to identify compounds that promote myeloid differentiation with MLPCN compound set	platelet measurement	HOXA9	pathwayBased	0.11546743277679	4	358556	3721
qHTS for Agonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1): primary screen	platelet measurement	RAPGEF3	targetBased	0.101857873114495	6	364614	268
qHTS for Antagonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1): primary screen	platelet measurement	RAPGEF3	targetBased	0.101857873114495	6	364614	517
qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS	platelet measurement	GNAS	targetBased	0.123616930936479	6	334825	423
qHTS for Antagonists of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS	platelet measurement	GNAS	targetBased	0.123616930936479	6	337446	1356
Toxoplasma gondii inhibition HTS in the presence of IFN-y	platelet measurement	IFNG	targetBased	0.168333724336481	59	67275	2509
Primary cell-based high throughput screening assay to measure STAT1 activation	platelet measurement	STAT1 activation	pathwayBased	0.127418836195698	12	195980	5134
Primary cell-based high throughput screening assay to measure STAT1 inhibition	platelet measurement	STAT1	targetBased	0.127418836195698	12	195980	695
qHTS for Inhibitors of Glutaminase (GLS)	platelet measurement	GLS	targetBased	0.177130490855318	8	405291	844
uHTS for the identification of compounds that potentiate TRAIL-induced apoptosis of cancer cells	platelet measurement	TNFSF10	targetBased	0.165277784933948	13	217035	883
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	platelet measurement	JAK2	targetBased	0.266325931867185	61	217959	2390
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of the interaction of the Ras and Rab interactor 1 protein (Rin1) and the c-abl oncogene 1, non-receptor tyrosine kinase (Abl)	platelet measurement	ABL1_interaction	targetBased	0.134861797520465	5	359207	1432
qHTS for Inhibitors of TGF-b	platelet measurement	TGFB1	pathwayBased	0.117472159025654	525	403345	4970
qHTS Assay for Inhibitors of BAZ2B	platelet measurement	BAZ2B_modulators	targetBased	0.146291233550169	5	356826	15709
Primary Cell-Based Assay to Identify Agonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	platelet measurement	S1PR4	targetBased	0.169496537993601	4	217959	771
Primary Cell-Based Assay to Identify Antagonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	platelet measurement	S1PR4	targetBased	0.169496537993601	4	217959	569
Fluorescence-based biochemical primary high throughput screening assay to identify activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF)	platelet measurement	TNNI3	targetBased	0.126483436314043	5	335239	801
Fluorescence-based biochemical primary high throughput screening assay to identify inhibitors of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF)	platelet measurement	TNNI3	targetBased	0.126483436314043	5	335238	390
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	platelet measurement	PPARG	targetBased	0.161838730234839	23	99314	335
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	platelet measurement	PPARG	targetBased	0.161838730234839	23	196176	782
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	platelet measurement	PPARG	targetBased	0.161838730234839	23	99314	390
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	platelet measurement	PPARG	targetBased	0.161838730234839	23	196177	811
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	platelet measurement	PPARG	targetBased	0.161838730234839	23	196176	670
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	platelet measurement	PPARG	targetBased	0.161838730234839	23	196177	519
USP30 deubiquitinase inhibition: Primary qHTS	platelet measurement	USP30	targetBased	0.129359049263018	6	47480	2500
uHTS Luminescent assay for identification of inhibitors of Sentrin-specific protease 7 (SENP7)	platelet measurement	SENP7	targetBased	0.131996979185201	5	331670	4902
qHTS Assay for NPC1 Promoter Activators	platelet measurement	NPC1	pathwayBased	0.148845301897143	8	320682	7575
HTS Discovery of Chemical Inhibitors of HePTP, a Leukemia Target	platelet measurement	PTPN7	targetBased	0.145128039380624	4	112381	724
Luminescence Cell-Based Primary HTS to Identify Inhibitors of A1 Apoptosis.	platelet measurement	BCL2L11_inhibitors	targetBased	0.161970878909033	16	325630	216
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors of ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 (ASAP1)	platelet measurement	ASAP1_inhibitors	targetBased	0.17218159989381	6	362577	680
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb via a fluorescence resonance energy transfer (FRET) assay.	platelet measurement	RUNX1	targetBased	0.171701176779572	26	215667	993
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay.	platelet measurement	RUNX1	targetBased	0.171701176779572	26	218234	1620
uHTS Luminescent assay for identification of inhibitors of NALP3 in yeast	platelet measurement	NLRP3	targetBased	0.222517419805386	24	330392	1295
MLPCN ERAP1 Measured in Biochemical System Using Plate Reader - 7016-01_Inhibitor_SinglePoint_HTS_Activity	platelet measurement	ERAP1_inhibitors	targetBased	0.164716790199056	6	335777	499
Fluorescence-based primary biochemical high throughput screening assay to identify inhibitors of human diacylglycerol lipase, beta (DAGLB)	platelet measurement	DAGLB_inhibitors	targetBased	0.160438740237439	4	343468	202
Primary biochemical high-throughput screening assay to measure P97 ATPase inhibition	platelet measurement	VCP	targetBased	0.146927540553294	7	217959	923
Primary Cell-based High Throughput Screening Assay for Inhibitors of Wee1 Degradation	platelet measurement	WEE1	targetBased	0.130847462316877	6	217959	2616
qHTS Assay for Activators of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease	platelet measurement	GAA	targetBased	0.141246425980472	6	199169	715
qHTS Assay for Inhibitors and Activators of Human alpha-Glucosidase Cleavage of Glycogen	platelet measurement	GAA_inhibitors	targetBased	0.141246425980472	6	302297	1165
Primary biochemical high throughput screening assay to identify inhibitors of BCL2-related protein, long isoform (BCLXL).	platelet measurement	BCL2L1_modulators	targetBased	0.176240813183896	18	314998	2199
qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding	platelet measurement	MAPT	pathwayBased	0.127891106580163	4	267412	5703
qHTS Assay for Tau Filament Binding	platelet measurement	MAPT	targetBased	0.127891106580163	4	69668	1391
qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization	platelet measurement	MAPT	pathwayBased	0.127891106580163	4	271402	1048
AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of microphthalmia-associated transcription factor (MITF)	platelet measurement	MITF inhibitors	targetBased	0.176561313972995	6	642362	5830
MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Inhibitor_SinglePoint_HTS_Activity	platelet measurement	MITF	targetBased	0.176561313972995	6	331360	2760
Alphascreen assay for small molecules abrogating mHTT-CaM Interaction	platelet measurement	HTT	targetBased	0.163343730246752	8	189882	6790
Primary qHTS for Identification of Small Molecule Inhibitors of Huntingtin Promoter Activity	platelet measurement	HTT	targetBased	0.163343730246752	8	48068	449
qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Aggregate Formation (GFP)	platelet measurement	HTT	targetBased	0.163343730246752	8	220571	2380
qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Cytoprotection (ATP)	platelet measurement	HTT	targetBased	0.163343730246752	8	223611	305
Primary qHTS for Inhibitors of ATXN expression	platelet measurement	ATXN2_repressors	targetBased	0.14230403247518	32	358434	2554
Primary HTS Assay for S1P3 Antagonists	platelet measurement	S1PR3	targetBased	0.15803751274313	14	169141	462
FRET-based HTS for detection of RAD52 Inhibitors Measured in Biochemical System Using Plate Reader - 7018-01_Inhibitor_SinglePoint_HTS_Activity_Set2	erythrocyte measurement	RAD52	targetBased	0.149258278453076	5	352074	1608
High Content Assay for Compounds that inhibit the Assembly of the Perinucleolar Compartment	erythrocyte measurement	PTBP1	targetBased	0.128010420467233	6	139718	4338
Primary Cell-based High Throughput Screening assay for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA)	erythrocyte measurement	RORA	pathwayBased	0.118462246789193	4	64908	979
Primary Cell-based High Throughput Screening assay for inhibitors of the Retinoic Acid Receptor-related orphan receptor A (RORA)	erythrocyte measurement	RORA	pathwayBased	0.118462246789193	4	64908	278
HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Inhibitor_SinglePoint_HTS_Activity	erythrocyte measurement	SCARB1	targetBased	0.178436333330801	7	319204	3065
HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Activator_SinglePoint_HTS_Activity	erythrocyte measurement	SCARB1	targetBased	0.178436333330801	7	316970	306
HTS to identify compounds that promote myeloid differentiation with MLPCN compound set	erythrocyte measurement	HOXA9	pathwayBased	0.156282049774808	10	358556	3721
HTS Assay for Peg3 Promoter Inhibitors	erythrocyte measurement	PPP1R15A	targetBased	0.144881433709427	5	359244	6145
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	erythrocyte measurement	JAK2	targetBased	0.173381290291104	29	217959	2390
Identification of CBX7 inhibitors - Primary Alpha Screen	erythrocyte measurement	Chromobox protein homolog 7 inhibitors	targetBased	0.145163145603542	4	64999	724
qHTS for Inhibitors of Polymerase Iota	erythrocyte measurement	POLI	targetBased	0.104522513586388	15	386063	3989
Identification of Molecular Probes that Activate MRP-1	erythrocyte measurement	ABCC1_activators	targetBased	0.184360993816007	11	138717	842
uHTS luminescence assay for the identification of compounds that inhibit NOD1	erythrocyte measurement	NOD1	targetBased	0.163560746253176	4	289422	2997
EZH2/PRC2 methyltransferase inhibitors Measured in Biochemical System Using Plate Reader - 2125-01_Inhibitor_SinglePoint_HTS_Activity	erythrocyte measurement	EZH2_inhibitors	targetBased	0.137409930776384	5	57013	201
Fluorescence Biochemical Primary HTS to Identify Inhibitors of GASC-1 Activity	erythrocyte measurement	KDM4C	targetBased	0.149405206600185	6	326066	228
High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Primary Screen	erythrocyte measurement	NFKB1	pathwayBased	0.180695327336313	10	193265	3100
uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay	erythrocyte measurement	NFKB1	pathwayBased	0.180695327336313	10	359244	3094
HTS for Identification of VLA-4 Allosteric Modulators from MLPCN library	erythrocyte measurement	ITGA4	targetBased	0.165057756891608	6	326888	645
uHTS identification of Caspase-8 TRAIL sensitizers in a luminesence assay	erythrocyte measurement	TNFRSF10B	targetBased	0.157996914415155	7	363840	3764
Fluorescence-based biochemical high throughput primary assay to identify inhibitors of phospholipase C isozymes (PLC-gamma1).	erythrocyte measurement	PLCG1	targetBased	0.16250682867285	5	369953	3123
HTS for PAX8 inhibitors using PAX8 luciferase reporter gene assay in RMG-I cells Measured in Cell-Based System Using Plate Reader - 7054-01_Inhibitor_SinglePoint_HTS_Activity	erythrocyte measurement	PAX8	targetBased	0.145553287572739	5	353950	4145
Primary Cell-Based Assay to Identify Agonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	erythrocyte measurement	S1PR4	targetBased	0.117979848288467	4	217959	771
Primary Cell-Based Assay to Identify Antagonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	erythrocyte measurement	S1PR4	targetBased	0.117979848288467	4	217959	569
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	erythrocyte measurement	PPARG	targetBased	0.174465946777247	15	99314	335
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	erythrocyte measurement	PPARG	targetBased	0.174465946777247	15	196176	782
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	erythrocyte measurement	PPARG	targetBased	0.174465946777247	15	99314	390
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	erythrocyte measurement	PPARG	targetBased	0.174465946777247	15	196177	811
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	erythrocyte measurement	PPARG	targetBased	0.174465946777247	15	196176	670
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	erythrocyte measurement	PPARG	targetBased	0.174465946777247	15	196177	519
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of 5-meCpG-binding domain protein 2 (MBD2)-DBD binding to methylated oligonucleotide	erythrocyte measurement	MBD2	targetBased	0.1553513228794	14	369953	1149
E3 Ligase HTS_1536	erythrocyte measurement	MDM2	targetBased	0.163947498391108	9	207811	220
uHTS Luminescent assay for identification of inhibitors of Sentrin-specific protease 7 (SENP7)	erythrocyte measurement	SENP7	targetBased	0.152333737646456	11	331670	4902
HTS for Estrogen Receptor-beta Coactivator Binding inhibitors	erythrocyte measurement	ESR2_inhibitors	targetBased	0.187156029435192	6	86095	1114
qHTS Assay for NPC1 Promoter Activators	erythrocyte measurement	NPC1	pathwayBased	0.165269916985511	11	320682	7575
Inhibitors of CDC25B-CDK2/CyclinA interaction	erythrocyte measurement	Inhibitors of CDC25B-CDK2/CyclinA interaction	targetBased	0.16785739706934	17	93798	679
qHTS Assay for Identifying a Potential Treatment of Ataxia-Telangiectasia	erythrocyte measurement	ATM_modulators	targetBased	0.156476387170661	17	322361	619
Fluorescence-based biochemical high throughput primary assay to identify inhibitors of phospholipase C isozymes (PLC-beta3).	erythrocyte measurement	PLCB3	targetBased	0.141374594372333	9	369953	662
Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2	erythrocyte measurement	THRB	targetBased	0.183437542238677	28	276265	806
Luminescence Cell-Based Primary HTS to Identify Inhibitors of A1 Apoptosis.	erythrocyte measurement	BCL2L11_inhibitors	targetBased	0.184049300491122	69	325630	216
uHTS Fluorescent assay for identification of inhibitors of hexokinase domain containing I (HKDC1)	erythrocyte measurement	HKDC1	targetBased	0.180825362055404	21	340696	540
Dyrk1 A HTS Measured in Biochemical System Using Plate Reader - 2124-01_Inhibitor_SinglePoint_HTS_Activity	erythrocyte measurement	DYRK1A_inhibitors	targetBased	0.11310793032075	4	310014	1321
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb via a fluorescence resonance energy transfer (FRET) assay.	erythrocyte measurement	RUNX1	targetBased	0.10821154359046	17	215667	993
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay.	erythrocyte measurement	RUNX1	targetBased	0.10821154359046	17	218234	1620
Inhibitors of USP1/UAF1: Primary Screen	erythrocyte measurement	USP1	targetBased	0.126890686335308	11	389569	904
uHTS Luminescent assay for identification of inhibitors of NALP3 in yeast	erythrocyte measurement	NLRP3	targetBased	0.151524390547044	4	330392	1295
Primary biochemical high-throughput screening assay to measure P97 ATPase inhibition	erythrocyte measurement	VCP	targetBased	0.134802034350887	6	217959	923
HTS of Smad transcription factor inhibitors	erythrocyte measurement	SMAD3	targetBased	0.102602889315947	4	88033	251
Primary cell-based high throughput screening assay to measure STAT3 activation	erythrocyte measurement	STAT3	pathwayBased	0.139682355782146	6	194666	1772
Primary cell-based high throughput screening assay to measure STAT3 inhibition	erythrocyte measurement	STAT3	pathwayBased	0.139682355782146	6	194666	1722
Primary biochemical high-throughput screening assay for inhibitors of Focal Adhesion Kinase (FAK)	erythrocyte measurement	PTK2	targetBased	0.142586695487658	4	96879	811
qHTS Assay for Activators of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease	erythrocyte measurement	GAA	targetBased	0.120014820841895	8	199169	715
qHTS Assay for Inhibitors and Activators of Human alpha-Glucosidase Cleavage of Glycogen	erythrocyte measurement	GAA_inhibitors	targetBased	0.120014820841895	8	302297	1165
Inhibition of the MLL-AF4-AF9 Interaction in Pediatric Leukemia Measured in Biochemical System Using Plate Reader - 2160-01_Inhibitor_SinglePoint_HTS_Activity	erythrocyte measurement	MLLT3	targetBased	0.105303794929264	9	344459	1627
qHTS screen for small molecules that induce genotoxicity in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1	erythrocyte measurement	ATAD5_inhibitors	targetBased	0.141418793413229	7	330109	4174
qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1	erythrocyte measurement	ATAD5_inhibitors	targetBased	0.141418793413229	7	330107	7652
Primary qHTS for Inhibitors of ATXN expression	erythrocyte measurement	ATXN2_repressors	targetBased	0.124551309277167	12	358434	2554
Identification of agents that induce E-selectin on human endothelial cells Measured in Cell-Based System Using Imaging - 2152-01_Activator_SinglePoint_HTS_Activity	protein measurement	SELE	targetBased	0.105967622480289	21	257988	963
Primary HTS assay for chemical inhibitors of TNF alpha stimulated E-Selectin expression	protein measurement	E-selectinExpression	targetBased	0.105967622480289	21	118096	843
High Content Assay for Compounds that inhibit the Assembly of the Perinucleolar Compartment	protein measurement	PTBP1	targetBased	0.146500072165132	16	139718	4338
Fluorescence-based primary biochemical high throughput screening assay to identify inhibitors of Protein Phosphatase 5 (PP5).	protein measurement	PPP5C	targetBased	0.141019132498672	5	314999	564
Primary cell-based high-throughput screening assay for identification of compounds that inhibit KCNQ1 potassium channels	protein measurement	KCNQ1	targetBased	0.165881078342401	10	305610	3878
Primary cell-based high-throughput screening assay for identification of compounds that potentiate/activate KCNQ1 potassium channels	protein measurement	KCNQ1	targetBased	0.165881078342401	10	305610	1082
HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Inhibitor_SinglePoint_HTS_Activity	protein measurement	SCARB1	targetBased	0.267701468232528	86	319204	3065
HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Activator_SinglePoint_HTS_Activity	protein measurement	SCARB1	targetBased	0.267701468232528	86	316970	306
HTS Assay for Peg3 Promoter Inhibitors	protein measurement	PPP1R15A	targetBased	0.150134111895518	7	359244	6145
qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS	protein measurement	GNAS	targetBased	0.1113252705426	7	334825	423
qHTS for Antagonists of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS	protein measurement	GNAS	targetBased	0.1113252705426	7	337446	1356
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of the interaction of the Ras and Rab interactor 1 protein (Rin1) and the c-abl oncogene 1, non-receptor tyrosine kinase (Abl)	protein measurement	ABL1_interaction	targetBased	0.127565991689681	16	359207	1432
uHTS identification of modulators of interaction between CendR and NRP-1 using Fluorescence Polarization assay	protein measurement	NRP1	targetBased	0.183705636615831	11	363840	3086
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype	protein measurement	RAB2A	targetBased	0.145803990765175	6	194628	365
qHTS for Inhibitors of TGF-b	protein measurement	TGFB1	pathwayBased	0.121976565186817	45	403345	4970
uHTS identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay	erythrocyte measurement	UBE2N	targetBased	0.149939193019733	12	330393	1538
Primary HTS Assay for S1P3 Antagonists	erythrocyte measurement	S1PR3	targetBased	0.154034292111585	10	169141	462
qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding	erythrocyte measurement	MAPT	pathwayBased	0.102195779855895	18	267412	5703
qHTS Assay for Tau Filament Binding	erythrocyte measurement	MAPT	targetBased	0.102195779855895	18	69668	1391
qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization	erythrocyte measurement	MAPT	pathwayBased	0.102195779855895	18	271402	1048
AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of microphthalmia-associated transcription factor (MITF)	erythrocyte measurement	MITF inhibitors	targetBased	0.188770989432462	7	642362	5830
MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Inhibitor_SinglePoint_HTS_Activity	erythrocyte measurement	MITF	targetBased	0.188770989432462	7	331360	2760
EZH2/PRC2 methyltransferase inhibitors Measured in Biochemical System Using Plate Reader - 2125-01_Inhibitor_SinglePoint_HTS_Activity	protein measurement	EZH2_inhibitors	targetBased	0.138271830446647	8	57013	201
High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Primary Screen	protein measurement	NFKB1	pathwayBased	0.162312524085441	150	193265	3100
uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay	protein measurement	NFKB1	pathwayBased	0.162312524085441	150	359244	3094
Inhibitors of the vitamin D receptor (VDR): qHTS	protein measurement	VDR	targetBased	0.122096777583143	11	394050	3624
Flow Cytometric HTS Screen for inhibitors of the ABC transporter ABCB6 for MLPCN Compound Set	protein measurement	ABCB6_inhibitors	targetBased	0.139723124673437	8	362098	692
Nrf2 qHTS screen for inhibitors	protein measurement	nrf2Inhibitors	targetBased	0.179407332332791	16	360873	7438
qHTS of Nrf2 Activators	protein measurement	Nrf2 activators	pathwayBased	0.179407332332791	16	403871	1243
Luminescence-based cell-based primary high throughput screening assay to identify inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2)	protein measurement	NR5A2	targetBased	0.181432568923652	7	363803	458
uHTS identification of Caspase-8 TRAIL sensitizers in a luminesence assay	protein measurement	TNFRSF10B	targetBased	0.162382446704469	9	363840	3764
uHTS for the identification of compounds that potentiate TRAIL-induced apoptosis of cancer cells	protein measurement	TNFSF10	targetBased	0.201872228032074	28	217035	883
qHTS for Inhibitors of Cell Surface uPA Generation	protein measurement	PLAU	targetBased	0.15929637770055	4	325247	1021
Primary cell-based high-throughput screening assay for identification of compounds that inhibit/block inward-rectifying potassium ion channel Kir2.1	protein measurement	KCNJ2	targetBased	0.142925772381362	9	305610	2592
Identification of Novel Modulators of Cl- dependent Transport Process via HTS: Primary Screen	protein measurement	SLC12A5	targetBased	0.100935182033576	5	189132	4127
Luminescence-based cell-based primary high throughput screening assay to identify inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3)	protein measurement	NCOA3	targetBased	0.13990303661846	5	359207	620
HTS for PAX8 inhibitors using PAX8 luciferase reporter gene assay in RMG-I cells Measured in Cell-Based System Using Plate Reader - 7054-01_Inhibitor_SinglePoint_HTS_Activity	protein measurement	PAX8	targetBased	0.171242157107197	34	353950	4145
Luminescence Cell-Based Primary HTS to Identify Inhibitors of STK33	protein measurement	STK33	targetBased	0.109065523030079	4	37341	2812
Luminescence Cell-Free Homogenous Primary HTS to Identify Inhibitors of Serine/Threonine Kinase 33 Activity	protein measurement	STK33	targetBased	0.109065523030079	4	321808	235
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	protein measurement	PPARG	targetBased	0.242501320546101	89	99314	335
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	protein measurement	PPARG	targetBased	0.242501320546101	89	196176	782
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	protein measurement	PPARG	targetBased	0.242501320546101	89	99314	390
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	protein measurement	PPARG	targetBased	0.242501320546101	89	196177	811
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	protein measurement	PPARG	targetBased	0.242501320546101	89	196176	670
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	protein measurement	PPARG	targetBased	0.242501320546101	89	196177	519
qHTS assay for inhibitors of human lactate dehydrogenase	protein measurement	lactateDehydrogenaseInhibitors	targetBased	0.114966738956896	11	476056	732
E3 Ligase HTS_1536	protein measurement	MDM2	targetBased	0.122876320318303	4	207811	220
Luminescence cell-based high throughput primary assay to identify inhibitors of TEAD-YAP interaction.	protein measurement	YAP1	targetBased	0.188459559374173	16	639428	9218
uHTS Luminescent assay for identification of inhibitors of Sentrin-specific protease 7 (SENP7)	protein measurement	SENP7	targetBased	0.15185196430511	9	331670	4902
HTS for Estrogen Receptor-beta Coactivator Binding inhibitors	protein measurement	ESR2_inhibitors	targetBased	0.188278440455693	7	86095	1114
Luminescence-based cell-based primary high throughput screening assay to identify inhibitors of the Steroid Receptor Coactivator 2 (SRC2; NCOA2)	protein measurement	NCOA2	targetBased	0.166236571590858	13	368927	620
qHTS assay for re-activators of p53 using a Luc reporter	protein measurement	TP53	pathwayBased	0.108778347525279	128	321427	201
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Nonpermissive Temperature	protein measurement	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.108778347525279	128	54509	528
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Permissive Temperature	protein measurement	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.108778347525279	128	54513	338
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature	protein measurement	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.108778347525279	128	125394	1890
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Permissive Temperature	protein measurement	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.108778347525279	128	124022	1156
HTS Assay for Inhibitors of Akt Phophorylation: Primary Screen	protein measurement	AKT1_inhibitors	targetBased	0.123486358620187	51	356517	1139
qHTS assay to identify small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway	protein measurement	RORCgammaPathwayInhibitors	pathwayBased	0.101899038161156	4	7671	874
VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity	protein measurement	RORC	targetBased	0.101899038161156	4	304060	10600
qHTS for inhibitors of ROR gamma transcriptional activity	protein measurement	RORCgammaPathwayInhibitors	pathwayBased	0.101899038161156	4	305439	16717
qHTS Assay for NPC1 Promoter Activators	monocyte count	NPC1	pathwayBased	0.134760572990049	4	320682	7575
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of the plasma platelet activating factor acetylhydrolase (pPAFAH)	protein measurement	PLA2G7	targetBased	0.150380714737586	4	326024	4934
Beta-Arrestin HTS for Positive Allosteric Modulators of the Human D2 Dopamine Receptor: Agonists	protein measurement	D2_agonists	targetBased	0.134428227948703	9	359518	300
HTS Assay for Allosteric Agonists of the Human D2 Dopamine Receptor: Primary Screen for Agonists	protein measurement	D2_agonists	targetBased	0.134428227948703	9	335652	1779
Beta-Arrestin HTS for Positive Allosteric Modulators of the Human D2 Dopamine Receptor: Potentiators	protein measurement	D2_PAMs	targetBased	0.134428227948703	9	357537	806
HTS Assay for Positive Allosteric Modulators of the Human D2 Dopamine Receptor: Primary Screen for Potentiators	protein measurement	D2_PAMs	targetBased	0.134428227948703	9	339887	1178
Beta-Arrestin HTS for Positive Allosteric Modulators of the Human D2 Dopamine Receptor: Antagonists	protein measurement	D2_antagonists	targetBased	0.134428227948703	9	362274	1056
HTS Assay for Allosteric Antagonists of the Human D2 Dopamine Receptor: Primary Screen for Antagonists	protein measurement	D2_antagonists	targetBased	0.134428227948703	9	336308	6862
qHTS Assay for Identifying a Potential Treatment of Ataxia-Telangiectasia	protein measurement	ATM_modulators	targetBased	0.126722220627287	9	322361	619
Fluorescence-based biochemical high throughput primary assay to identify inhibitors of phospholipase C isozymes (PLC-beta3).	protein measurement	PLCB3	targetBased	0.123650907837128	9	369953	662
Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2	protein measurement	THRB	targetBased	0.188359016130503	19	276265	806
Luminescence Cell-Based Primary HTS to Identify Inhibitors of A1 Apoptosis.	protein measurement	BCL2L11_inhibitors	targetBased	0.180494528698707	39	325630	216
uHTS Fluorescent assay for identification of inhibitors of hexokinase domain containing I (HKDC1)	protein measurement	HKDC1	targetBased	0.182791348564474	40	340696	540
Inhibitors of USP1/UAF1: Primary Screen	protein measurement	USP1	targetBased	0.110271629074225	25	389569	904
uHTS Luminescent assay for identification of inhibitors of NALP3 in yeast	protein measurement	NLRP3	targetBased	0.206003768550924	74	330392	1295
HTS of Smad transcription factor inhibitors	protein measurement	SMAD3	targetBased	0.172188009619519	11	88033	251
Primary cell-based high throughput screening assay to measure STAT3 activation	protein measurement	STAT3	pathwayBased	0.129955440087406	35	194666	1772
Primary cell-based high throughput screening assay to measure STAT3 inhibition	protein measurement	STAT3	pathwayBased	0.129955440087406	35	194666	1722
Primary biochemical high-throughput screening assay for inhibitors of Focal Adhesion Kinase (FAK)	protein measurement	PTK2	targetBased	0.146103635646066	9	96879	811
Primary HTS and Confirmation Assays for S1P1 Agonists and Agonism Potentiators	protein measurement	S1PR1	targetBased	0.162715301061526	7	55710	315
qHTS Assay for Activators of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease	protein measurement	GAA	targetBased	0.14578633293814	6	199169	715
qHTS Assay for Inhibitors and Activators of Human alpha-Glucosidase Cleavage of Glycogen	protein measurement	GAA_inhibitors	targetBased	0.14578633293814	6	302297	1165
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	protein measurement	FGB_inhibitors	targetBased	0.219993390455688	24	369953	760
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	protein measurement	FGB_inhibitors	targetBased	0.219993390455688	24	369953	498
Identification of agents that induce E-selectin on human endothelial cells Measured in Cell-Based System Using Imaging - 2152-01_Activator_SinglePoint_HTS_Activity	hematologic disease	SELE	targetBased	0.145722728195302	136	257988	963
Primary HTS assay for chemical inhibitors of TNF alpha stimulated E-Selectin expression	hematologic disease	E-selectinExpression	targetBased	0.145722728195302	136	118096	843
uHTS absorbance assay for the identification of compounds that inhibit PHOSPHO1	protein measurement	PHOSPHO1	targetBased	0.152637709080996	14	288321	3164
qHTS Assay to Identify Small Molecule Activators of BRCA1 Expression	hematologic disease	BRCA1 activation	pathwayBased	0.310265658070919	347	376029	3978
Absorbance-based biochemical primary high throughput screening assay to identify activators of Methionine sulfoxide reductase A (MsrA)	protein measurement	MSRA	targetBased	0.128207116883365	5	362026	1074
Absorbance-based biochemical primary high throughput screening assay to identify inhibitors of Methionine sulfoxide reductase A (MsrA)	protein measurement	MSRA	targetBased	0.128207116883365	5	362577	2709
qHTS screen for small molecules that induce genotoxicity in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1	protein measurement	ATAD5_inhibitors	targetBased	0.119423272277985	4	330109	4174
qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1	protein measurement	ATAD5_inhibitors	targetBased	0.119423272277985	4	330107	7652
uHTS identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay	protein measurement	UBE2N	targetBased	0.16461218653353	11	330393	1538
Primary Cell-based High Throughput Screening assay for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA)	hematologic disease	RORA	pathwayBased	0.12775148895431	11	64908	979
Primary Cell-based High Throughput Screening assay for inhibitors of the Retinoic Acid Receptor-related orphan receptor A (RORA)	hematologic disease	RORA	pathwayBased	0.12775148895431	11	64908	278
uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (PABP)	hematologic disease	PABPC1	targetBased	0.18446933312392	17	290915	2982
uHTS identification of microRNA-mediated mRNA deadenylation inhibitors by fluoresence polarization assay	hematologic disease	PABPC1	targetBased	0.18446933312392	17	359244	1307
Fluorescence polarization to screen for inhibitors that disrupt the protein-protein interaction between Keap1 and Nrf2 Measured in Biochemical System Using Plate Reader - 2119-01_Inhibitor_SinglePoint_HTS_Activity	hematologic disease	KEAP1	targetBased	0.164314709782037	44	336894	489
uHTS identification of small molecule antagonists of the kappa opioid receptor via a luminescent beta-arrestin assay	hematologic disease	OPRK1	targetBased	0.204252632316027	17	290355	265
Luminescence-based cell-based primary high throughput screening assay to identify inhibitors of the Steroid Receptor Coactivator 1 (SRC1; NCOA1)	hematologic disease	NCOA1	targetBased	0.125935071006915	14	359206	428
qHTS Assay for Identification of Novel General Anesthetics	hematologic disease	FTL	targetBased	0.227016759686415	21	341499	255
Luminescence-based cell-based primary high throughput screening assay to identify inhibitors of COUP-TFII (NR2F2)	protein measurement	NR2F2	targetBased	0.158312800549451	14	369953	2602
AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of microphthalmia-associated transcription factor (MITF)	protein measurement	MITF inhibitors	targetBased	0.217568071572442	13	642362	5830
MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Inhibitor_SinglePoint_HTS_Activity	protein measurement	MITF	targetBased	0.217568071572442	13	331360	2760
qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS	hematologic disease	GNAS	targetBased	0.171441050375321	48	334825	423
qHTS for Antagonists of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS	hematologic disease	GNAS	targetBased	0.171441050375321	48	337446	1356
qHTS for Suppressors of FUS Proteinopathy: Primary screen using FUS-linked yeast assay	hematologic disease	FUS_asupressors	targetBased	0.163333006423631	75	385746	932
HTS of Estrogen Receptor- alpha Coactivator Binding inhibitors	hematologic disease	ESR1_inhibitors	targetBased	0.240303472626445	385	86095	1442
HTS of Estrogen Receptor- alpha Coactivator Binding Potentiators	hematologic disease	ESR1_modulators	targetBased	0.240303472626445	385	86095	1151
qHTS Assay for Inhibitors of the ERK Signaling Pathway using a Homogeneous Screening Assay	hematologic disease	MAPK1	pathwayBased	0.272020239690185	119	70898	707
qHTS Assay for Inhibitors of the ERK Signaling Pathway using a Homogeneous Screening Assay; Stimulation with EGF	hematologic disease	MAPK1	pathwayBased	0.272020239690185	119	131324	544
Identification of CBX7 inhibitors - Primary Alpha Screen	hematologic disease	Chromobox protein homolog 7 inhibitors	targetBased	0.121446119712274	15	64999	724
ROC1-CUL1 CTD Inhibitor di-Ub FRET Primary HTS Screen	hematologic disease	RBX1	targetBased	0.226963918498602	635	143816	859
Luminescence-based cell-based primary high throughput screening assay to identify agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A)	hematologic disease	HTR2A	targetBased	0.14331557792472	13	363803	2412
Primary qHTS for Inhibitors of ATXN expression	protein measurement	ATXN2_repressors	targetBased	0.14846226871553	54	358434	2554
Primary HTS Assay for S1P3 Antagonists	protein measurement	S1PR3	targetBased	0.16671851203049	12	169141	462
Luminescence Cell-Free Homogenous Primary HTS to Identify Inhibitors of GSK-3 alpha	hematologic disease	GSK3A	targetBased	0.110169310138314	25	315412	318
Fluorescence polarization-based biochemical primary high throughput screening assay to identify activators of the Protein Kinase A-R1A (PKA-R1A) complex	hematologic disease	PRKAR1A	targetBased	0.154198318408052	12	343468	285
uHTS identification of Gli-Sufu Antagonists in a luminescence reporter assay	hematologic disease	GLI1	targetBased	0.112401274654112	134	338328	2501
Primary qHTS assay for inhibitors of Activation Induced Cytidine Deaminase (AID): AID signal	hematologic disease	AICDA_inhibitors	targetBased	0.29389767362962	495	90878	289
Luminescence-based cell-based primary high throughput screening assay to identify agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors	hematologic disease	OPRM1	targetBased	0.262589496411515	30	335239	991
Luminescence-based cell-based primary high throughput screening assay to identify inverse agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors	hematologic disease	OPRM1	targetBased	0.262589496411515	30	335239	695
Primary screen for compounds that activate Insulin promoter activity in TRM-6 cells	protein measurement	INS	targetBased	0.16158127906823	13	128695	1039
Primary screen for compounds that inhibit Insulin promoter activity in TRM-6 cells	protein measurement	INS	targetBased	0.16158127906823	13	127961	1153
Flow Cytometric HTS Screen for inhibitors of the ABC transporter ABCB6 for MLPCN Compound Set	hematologic disease	ABCB6_inhibitors	targetBased	0.250793839583365	74	362098	692
uHTS identification of HIF-2a Inhibitors in a luminesence assay	hematologic disease	HIF-2a_inhibitors	targetBased	0.28000788404909	254	363840	2624
Nrf2 qHTS screen for inhibitors	hematologic disease	nrf2Inhibitors	targetBased	0.202709891262469	148	360873	7438
qHTS of Nrf2 Activators	hematologic disease	Nrf2 activators	pathwayBased	0.202709891262469	148	403871	1243
qHTS for Inhibitors of Cell Surface uPA Generation	hematologic disease	PLAU	targetBased	0.240699632061758	109	325247	1021
Fluorescence-based biochemical high throughput primary assay to identify inhibitors of phospholipase C isozymes (PLC-gamma1).	hematologic disease	PLCG1	targetBased	0.209832168962647	62	369953	3123
HTS for PAX8 inhibitors using PAX8 luciferase reporter gene assay in RMG-I cells Measured in Cell-Based System Using Plate Reader - 7054-01_Inhibitor_SinglePoint_HTS_Activity	hematologic disease	PAX8	targetBased	0.108826957123296	64	353950	4145
qHTS Assay for Inhibitors of the Six1/Eya2 Interaction	hematologic disease	SIX1	targetBased	0.159673150443151	25	364053	2026
Screen for inhibitors of the SWI/SNF chromatin remodeling complex (esBAF) in mouse embryonic stem cells with Luciferase reporter assay Measured in Cell-Based System Using Plate Reader - 2141-01_Inhibitor_SinglePoint_HTS_Activity	hematologic disease	SMARCA4	targetBased	0.250479936208494	92	344733	7043
uHTS identification of DNMT1 inhibitors in a Fluorescent Molecular Beacon assay	hematologic disease	DNMT1	targetBased	0.251756640346989	806	359244	2975
Factor XIIa 1536 HTS	hematologic disease	F12_modulation	targetBased	0.29572516568838	48	217430	649
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	hematologic disease	PPARG	targetBased	0.202853393226659	225	99314	335
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	hematologic disease	PPARG	targetBased	0.202853393226659	225	196176	782
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	hematologic disease	PPARG	targetBased	0.202853393226659	225	99314	390
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	hematologic disease	PPARG	targetBased	0.202853393226659	225	196177	811
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	hematologic disease	PPARG	targetBased	0.202853393226659	225	196176	670
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	hematologic disease	PPARG	targetBased	0.202853393226659	225	196177	519
E3 Ligase HTS_1536	hematologic disease	MDM2	targetBased	0.227009918917606	455	207811	220
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac activated mutant	hematologic disease	RAC1	targetBased	0.148687014698745	13	194629	219
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac wildtype	hematologic disease	RAC1	targetBased	0.148687014698745	13	194628	521
Assay for Inhibitors of the beta-Arrestin-Adaptor Protein 2 Interaction That Mediate GPCR Degradation and Recycling	hematologic disease	ARRB1_inhibitors	targetBased	0.199916084618716	23	338373	1061
Luminescence cell-based high throughput primary assay to identify inhibitors of TEAD-YAP interaction.	hematologic disease	YAP1	targetBased	0.103235416669997	67	639428	9218
USP8 deubiquitinase inhibition: Primary qHTS	hematologic disease	USP8	targetBased	0.164205434553081	8	47480	2010
Luminescence-based cell-based primary high throughput screening assay to identify inhibitors of the Steroid Receptor Coactivator 2 (SRC2; NCOA2)	hematologic disease	NCOA2	targetBased	0.198388166432614	40	368927	620
High Throughput Screening for Cocaine Antagonists: Primary Screen	hematologic disease	SLC6A3	targetBased	0.123714170514315	56	108286	1415
Beta-Arrestin HTS for Positive Allosteric Modulators of the Human D2 Dopamine Receptor: Agonists	hematologic disease	D2_agonists	targetBased	0.214163454390645	25	359518	300
HTS Assay for Allosteric Agonists of the Human D2 Dopamine Receptor: Primary Screen for Agonists	hematologic disease	D2_agonists	targetBased	0.214163454390645	25	335652	1779
Beta-Arrestin HTS for Positive Allosteric Modulators of the Human D2 Dopamine Receptor: Potentiators	hematologic disease	D2_PAMs	targetBased	0.214163454390645	25	357537	806
HTS Assay for Positive Allosteric Modulators of the Human D2 Dopamine Receptor: Primary Screen for Potentiators	hematologic disease	D2_PAMs	targetBased	0.214163454390645	25	339887	1178
Beta-Arrestin HTS for Positive Allosteric Modulators of the Human D2 Dopamine Receptor: Antagonists	hematologic disease	D2_antagonists	targetBased	0.214163454390645	25	362274	1056
HTS Assay for Allosteric Antagonists of the Human D2 Dopamine Receptor: Primary Screen for Antagonists	hematologic disease	D2_antagonists	targetBased	0.214163454390645	25	336308	6862
qHTS of D3 Dopamine Receptor Antagonist: qHTS	hematologic disease	D3_antagonists	targetBased	0.203769574269982	22	364051	9106
qHTS of D3 Dopamine Receptor Agonist: qHTS	hematologic disease	D3_agonists	targetBased	0.203769574269982	22	407539	2380
qHTS of D3 Dopamine Receptor Potentiators: qHTS	hematologic disease	D3_PAMs	targetBased	0.203769574269982	22	407539	2380
Luminescence Cell-Based Primary HTS to Identify Inhibitors of A1 Apoptosis.	hematologic disease	BCL2L11_inhibitors	targetBased	0.180770886692703	457	325630	216
HTS for Inhibition of CaV1.3 ICDI/IQ interaction using a live-cell FRET assay Measured in Cell-Based System Using Plate Reader - 7081-01_Inhibitor_SinglePoint_HTS_Activity	hematologic disease	CACNA1D_inhibitors	targetBased	0.204968294939809	14	335531	328
uHTS of small molecular inhibitors for p47phox, a regulatory protein of NADPH oxidases (Noxs)	hematologic disease	p47phoxInhibitors	targetBased	0.238860816349537	127	217454	1142
HTS identification of compounds inhibiting the binding of CD11b/CD18 to fibrinogen via a luminescence assay.	hematologic disease	ITGB2	targetBased	0.297796297319023	657	92518	501
Discovery of small molecule inhibitors of the oncogenic and cytokinetic protein MgcRacGAP - Primary and Confirmatory Screens	hematologic disease	RACGAP1	targetBased	0.200937210596584	11	342059	2057
HTS for BAP1 Enzyme inhibitors	hematologic disease	BAP1_inhibitors	targetBased	0.18283149009844	12	71016	346
HTS of Estrogen Receptor- alpha Coactivator Binding inhibitors	protein measurement	ESR1_inhibitors	targetBased	0.177554609118309	17	86095	1442
HTS of Estrogen Receptor- alpha Coactivator Binding Potentiators	protein measurement	ESR1_modulators	targetBased	0.177554609118309	17	86095	1151
Identification of Molecular Probes that Activate MRP-1	protein measurement	ABCC1_activators	targetBased	0.184325867327738	11	138717	842
qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode)	protein measurement	GLP1R	targetBased	0.152554458663335	10	405130	6428
qHTS of GLP-1 Receptor Agonists	protein measurement	GLP1R agonists	targetBased	0.152554458663335	10	373462	23
qHTS of GLP-1 Receptor Inverse Agonists: (PAM Mode) (Taking the negative queue for PAMs)	protein measurement	GLP1R PAMs	targetBased	0.152554458663335	10	405130	6428
qHTS for Inhibitors of WRN Helicase	hematologic disease	WRN	targetBased	0.214970443678748	75	364011	1678
Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign	hematologic disease	TSHR	targetBased	0.115811074822284	69	329153	670
Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign	hematologic disease	TSHR	targetBased	0.115811074822284	69	329153	670
qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor	hematologic disease	TSHR	targetBased	0.115811074822284	69	72026	352
qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor: Activators of Intracellular cAMP Concentrations in Parental HEK 293	hematologic disease	TSHR	targetBased	0.115811074822284	69	72026	1794
Counterscreen for Oxytocin Receptor (OXTR) agonists: Fluorescence-based primary cell-based high throughput assay to identify agonists of the vasopressin 1 receptor (V1R)	hematologic disease	AVPR1A_agonists	targetBased	0.209767075025438	20	324747	813
Fluorescence polarization assay for PLK1 inhibitors	hematologic disease	PLK1	targetBased	0.134595460396245	149	97099	518
qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen	hematologic disease	PLK1	targetBased	0.134595460396245	149	364065	10181
HTS of Smad transcription factor inhibitors	hematologic disease	SMAD3	targetBased	0.22120918808814	77	88033	251
HTS for Beta-2AR agonists via FAP method	hematologic disease	ADRB2_activators	targetBased	0.149656915471975	29	339297	1446
Fluorescence-based biochemical high throughput primary assay to identify inhibitors of phospholipase C isozymes (PLC-gamma1).	protein measurement	PLCG1	targetBased	0.169430768535239	27	369953	3123
uHTS identification of APOBEC3A DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay	protein measurement	APOBEC3A_inhibitors	targetBased	0.111026623828136	4	331753	1372
qHTS Assay for NPC1 Promoter Activators	protein measurement	NPC1	pathwayBased	0.178600598674493	7	320682	7575
Fluorescence Cell-Free Homogeneous Primary HTS to Identify Inhibitors of Histone Deacetylase 3	hematologic disease	HDAC3	targetBased	0.240062958259791	289	318291	483
Fluorescence-based primary biochemical high throughput screening assay to identify inhibitors of human diacylglycerol lipase, beta (DAGLB)	protein measurement	DAGLB_inhibitors	targetBased	0.159195091716152	20	343468	202
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras wildtype	hematologic disease	HRAS	targetBased	0.284612218012725	110	194628	267
HTS for small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress	hematologic disease	DDIT3_inhibitors	targetBased	0.14249512211033	506	218654	8241
Fluorescence Intensity-based biochemical primary high throughput screening assay to identify activators of kallikrein-7 (K7) zymogen	protein measurement	KLK7	targetBased	0.139261675483	5	368927	3325
Primary cell-based screen for identification of compounds that inhibit the two-pore domain potassium channel KCNK3	protein measurement	KCNK3	targetBased	0.160949290708011	7	339674	2841
Primary HTS assay for 5-Hydroxytryptamine (Serotonin) Receptor Subtype 1a (5HT1a) agonists	hematologic disease	HTR1A	targetBased	0.136765862447888	9	64908	366
Primary HTS assay for 5-Hydroxytryptamine (Serotonin) Receptor Subtype 1a (5HT1a) antagonists	hematologic disease	HTR1A	targetBased	0.136765862447888	9	61606	416
HTS identification of compounds activating phosphomannose isomerase (PMI) via a fluorescence intensity assay using a near- saturating concentration of mannose 6-phosphat	hematologic disease	MPI	targetBased	0.307443154517656	259	194152	656
HTS identification of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay using a high concentration of mannose 6-phosphate	hematologic disease	MPI	targetBased	0.307443154517656	259	194152	1288
HTS identification of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay.	hematologic disease	MPI	targetBased	0.307443154517656	259	194152	814
Thrombin 1536 HTS	protein measurement	F2_modulation	targetBased	0.159999765704155	114	217233	557
AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of microphthalmia-associated transcription factor (MITF)	hematologic disease	MITF inhibitors	targetBased	0.222309169675994	75	642362	5830
MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Inhibitor_SinglePoint_HTS_Activity	hematologic disease	MITF	targetBased	0.222309169675994	75	331360	2760
Primary Cell-Based High-Throughput Screening to Identify Agonists of the Sphingosine 1-phosphate receptor 2 (S1P2)	protein measurement	S1PR2	targetBased	0.148639024241682	11	96879	447
Primary Cell-Based High-Throughput Screening to Identify Antagonists of the Sphingosine 1-phosphate receptor 2 (S1P2)	protein measurement	S1PR2	targetBased	0.148639024241682	11	96879	207
HCS assay for microtubule stabilizers	hematologic disease	TUBB	targetBased	0.224464684829917	899	195821	1625
HTS Assay for Compounds that Act as Agonists of the Vanilloid Receptor 1	hematologic disease	TRPV1	targetBased	0.205295646346043	53	316642	617
qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS	hematologic disease	TXNRD1	targetBased	0.212485647703202	70	386663	3977
uHTS for identification of Inhibitors of Mdm2/MdmX interaction in luminescent format.	hematologic disease	MDM4	targetBased	0.245345377985341	76	331671	10022
uHTS identification of small molecule modulators of NR3A	hematologic disease	GRIN3A	targetBased	0.19950347937188	7	339772	8480
Fluorescence-based cell-based primary high throughput screening assay to identify inhibitors of TLR9-MyD88 binding.	hematologic disease	TLR9	targetBased	0.224935464066758	299	343468	734
qHTS for Inhibitors of phosphatidylinositol 5-phosphate 4-kinase (PI5P4K)	hematologic disease	PIP4K2A	targetBased	0.153026818626855	15	328860	4078
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	hematologic disease	FGB_inhibitors	targetBased	0.321312955977006	137	369953	760
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	hematologic disease	FGB_inhibitors	targetBased	0.321312955977006	137	369953	498
Inhibition of the MLL-AF4-AF9 Interaction in Pediatric Leukemia Measured in Biochemical System Using Plate Reader - 2160-01_Inhibitor_SinglePoint_HTS_Activity	hematologic disease	MLLT3	targetBased	0.197143285120338	484	344459	1627
qHTS Assay for Inhibitors of Bloom's syndrome helicase (BLM)	hematologic disease	BLM_inhibitors	targetBased	0.318045691512211	2060	347933	673
uHTS identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay	platelet measurement	UBE2N	targetBased	0.162663386504292	6	330393	1538
uHTS identification of HIF-2a Inhibitors in a luminesence assay	erythrocyte measurement	HIF-2a_inhibitors	targetBased	0.152238130805393	27	363840	2624
Fluorescence-based primary biochemical high throughput screening assay to identify inhibitors of Protein Phosphatase 5 (PP5).	granulocyte count	PPP5C	targetBased	0.127635723633485	4	314999	564
Primary Cell-based High Throughput Screening assay for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA)	granulocyte count	RORA	pathwayBased	0.167661383357954	7	64908	979
Primary Cell-based High Throughput Screening assay for inhibitors of the Retinoic Acid Receptor-related orphan receptor A (RORA)	granulocyte count	RORA	pathwayBased	0.167661383357954	7	64908	278
qHTS for Inhibitors of Polymerase Iota	granulocyte count	POLI	targetBased	0.120098180411027	8	386063	3989
qHTS Assay for Inhibitors of the CtBP/E1A Interaction	granulocyte count	RBBP8	targetBased	0.119325357776129	5	335214	1652
Identification of Molecular Probes that Activate MRP-1	granulocyte count	ABCC1_activators	targetBased	0.158697424312905	4	138717	842
Luminescence-based primary cell-based high throughput screening assay to identify activators of the Aryl Hydrocarbon Receptor (AHR)	granulocyte count	AHR_activators	targetBased	0.159119770880158	5	324747	7988
Fluorescence Biochemical Primary HTS to Identify Inhibitors of GASC-1 Activity	granulocyte count	KDM4C	targetBased	0.112867260193194	4	326066	228
High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Primary Screen	granulocyte count	NFKB1	pathwayBased	0.18513174381754	12	193265	3100
uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay	granulocyte count	NFKB1	pathwayBased	0.18513174381754	12	359244	3094
qHTS of IL-2 Activators	granulocyte count	IL2	targetBased	0.117223347216307	6	364617	238
Inhibitors of the vitamin D receptor (VDR): qHTS	granulocyte count	VDR	targetBased	0.138290176998254	4	394050	3624
Primary cell-based high throughput screening assay to measure STAT1 activation	granulocyte count	STAT1 activation	pathwayBased	0.165597230755596	5	195980	5134
Primary cell-based high throughput screening assay to measure STAT1 inhibition	granulocyte count	STAT1	targetBased	0.165597230755596	5	195980	695
Small-molecule inhibitors of ST2 (IL1RL1)	granulocyte count	IL1RL1	targetBased	0.183196119439026	22	75924	1804
uHTS identification of Caspase-8 TRAIL sensitizers in a luminesence assay	granulocyte count	TNFRSF10B	targetBased	0.123597286560415	5	363840	3764
Primary cell-based high-throughput screening assay for identification of compounds that inhibit/block inward-rectifying potassium ion channel Kir2.1	granulocyte count	KCNJ2	targetBased	0.149192224479104	5	305610	2592
Primary cell-based high-throughput screening for identification of compounds that inhibit/block calcium-activated chloride channels (TMEM16A)	granulocyte count	ANO1_inhibitors	targetBased	0.133305234331518	6	306502	3633
Primary cell-based high-throughput screening for identification of compounds that activate/potentiate calcium-activated chloride channels (TMEM16A)	granulocyte count	ANO1_activators	targetBased	0.133305234331518	6	335180	1022
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	granulocyte count	PPARG	targetBased	0.180663597073388	16	99314	335
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	granulocyte count	PPARG	targetBased	0.180663597073388	16	196176	782
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	granulocyte count	PPARG	targetBased	0.180663597073388	16	99314	390
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	granulocyte count	PPARG	targetBased	0.180663597073388	16	196177	811
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	granulocyte count	PPARG	targetBased	0.180663597073388	16	196176	670
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	granulocyte count	PPARG	targetBased	0.180663597073388	16	196177	519
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of 5-meCpG-binding domain protein 2 (MBD2)-DBD binding to methylated oligonucleotide	granulocyte count	MBD2	targetBased	0.124133011291483	5	369953	1149
uHTS Luminescent assay for identification of inhibitors of Sentrin-specific protease 7 (SENP7)	granulocyte count	SENP7	targetBased	0.136527472426125	5	331670	4902
Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bfl-1	granulocyte count	BCL2A1_modulators	targetBased	0.166569265062523	11	194826	237
Luminescence Cell-Based Primary HTS to Identify Inhibitors of A1 Apoptosis.	granulocyte count	BCL2L11_inhibitors	targetBased	0.167542422167747	27	325630	216
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb via a fluorescence resonance energy transfer (FRET) assay.	granulocyte count	RUNX1	targetBased	0.106330648581902	27	215667	993
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay.	granulocyte count	RUNX1	targetBased	0.106330648581902	27	218234	1620
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of Protein Arginine Deiminase 4 (PAD4) (1536 HTS)	granulocyte count	PADI4	targetBased	0.163063979580053	4	326022	1334
qHTS Assay for Inhibitors of 15-hLO (15-human lipoxygenase)	granulocyte count	ALOX15_inhibitors	targetBased	0.248934591889753	26	73174	1034
HTS of Smad transcription factor inhibitors	granulocyte count	SMAD3	targetBased	0.188635730173878	19	88033	251
Primary HTS and Confirmation Assays for S1P1 Agonists and Agonism Potentiators	granulocyte count	S1PR1	targetBased	0.175191211772109	17	55710	315
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	granulocyte count	FGB_inhibitors	targetBased	0.180329667217648	4	369953	760
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	granulocyte count	FGB_inhibitors	targetBased	0.180329667217648	4	369953	498
Alphascreen assay for small molecules abrogating mHTT-CaM Interaction	granulocyte count	HTT	targetBased	0.133816872252241	4	189882	6790
Primary qHTS for Identification of Small Molecule Inhibitors of Huntingtin Promoter Activity	granulocyte count	HTT	targetBased	0.133816872252241	4	48068	449
qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Aggregate Formation (GFP)	granulocyte count	HTT	targetBased	0.133816872252241	4	220571	2380
qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Cytoprotection (ATP)	granulocyte count	HTT	targetBased	0.133816872252241	4	223611	305
Primary HTS Assay for S1P3 Antagonists	granulocyte count	S1PR3	targetBased	0.173505163157913	4	169141	462
Primary Cell-based High Throughput Screening assay for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA)	myeloid white cell count	RORA	pathwayBased	0.167661383357954	7	64908	979
Primary Cell-based High Throughput Screening assay for inhibitors of the Retinoic Acid Receptor-related orphan receptor A (RORA)	myeloid white cell count	RORA	pathwayBased	0.167661383357954	7	64908	278
Identification of Molecular Probes that Activate MRP-1	myeloid white cell count	ABCC1_activators	targetBased	0.158697424312905	4	138717	842
Luminescence-based primary cell-based high throughput screening assay to identify activators of the Aryl Hydrocarbon Receptor (AHR)	myeloid white cell count	AHR_activators	targetBased	0.159119770880158	5	324747	7988
Fluorescence Biochemical Primary HTS to Identify Inhibitors of GASC-1 Activity	myeloid white cell count	KDM4C	targetBased	0.112867260193194	4	326066	228
qHTS of IL-2 Activators	myeloid white cell count	IL2	targetBased	0.117223347216307	6	364617	238
Inhibitors of the vitamin D receptor (VDR): qHTS	myeloid white cell count	VDR	targetBased	0.138290176998254	4	394050	3624
Primary cell-based high throughput screening assay to measure STAT1 activation	myeloid white cell count	STAT1 activation	pathwayBased	0.165597230755596	5	195980	5134
Primary cell-based high throughput screening assay to measure STAT1 inhibition	myeloid white cell count	STAT1	targetBased	0.165597230755596	5	195980	695
Small-molecule inhibitors of ST2 (IL1RL1)	myeloid white cell count	IL1RL1	targetBased	0.183196119439026	22	75924	1804
uHTS identification of Caspase-8 TRAIL sensitizers in a luminesence assay	myeloid white cell count	TNFRSF10B	targetBased	0.123597286560415	5	363840	3764
Primary cell-based high-throughput screening assay for identification of compounds that inhibit/block inward-rectifying potassium ion channel Kir2.1	myeloid white cell count	KCNJ2	targetBased	0.149192224479104	5	305610	2592
uHTS Luminescent assay for identification of inhibitors of Sentrin-specific protease 7 (SENP7)	myeloid white cell count	SENP7	targetBased	0.136527472426125	5	331670	4902
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of Protein Arginine Deiminase 4 (PAD4) (1536 HTS)	myeloid white cell count	PADI4	targetBased	0.163063979580053	4	326022	1334
Fluorescence-based primary biochemical high throughput screening assay to identify inhibitors of human diacylglycerol lipase, beta (DAGLB)	myeloid white cell count	DAGLB_inhibitors	targetBased	0.162368990672268	9	343468	202
HTS of Smad transcription factor inhibitors	myeloid white cell count	SMAD3	targetBased	0.188635730173878	19	88033	251
Primary biochemical high throughput screening assay to identify inhibitors of BCL2-related protein, long isoform (BCLXL).	myeloid white cell count	BCL2L1_modulators	targetBased	0.146186549278231	5	314998	2199
uHTS identification of DNMT1 inhibitors in a Fluorescent Molecular Beacon assay	blood coagulation disease	DNMT1	targetBased	0.101916123224869	4	359244	2975
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb via a fluorescence resonance energy transfer (FRET) assay.	blood coagulation disease	RUNX1	targetBased	0.299139628488467	1588	215667	993
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay.	blood coagulation disease	RUNX1	targetBased	0.299139628488467	1588	218234	1620
Fluorescence-based cell-based primary high throughput screening assay to identify inhibitors of TLR9-MyD88 binding.	blood coagulation disease	TLR9	targetBased	0.140372238367863	5	343468	734
Primary HTS assay for chemical inhibitors of TNF alpha stimulated VCAM1 expression	granulocyte count	VCAM1_expression	targetBased	0.149444803936653	6	94498	457
Primary biochemical high throughput screening assay to identify inhibitors of BCL2-related protein, long isoform (BCLXL).	granulocyte count	BCL2L1_modulators	targetBased	0.146186549278231	5	314998	2199
HTS for developing T Cell Immune Modulators	neutrophil measurement	ITGAL	targetBased	0.137099289796612	5	326271	221
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	neutrophil measurement	JAK2	targetBased	0.169008493652309	4	217959	2390
HTS for Identification of VLA-4 Allosteric Modulators from MLPCN library	neutrophil measurement	ITGA4	targetBased	0.17432377214718	7	326888	645
qHTS Assay for Inhibitors of BAZ2B	neutrophil measurement	BAZ2B_modulators	targetBased	0.129935488315067	5	356826	15709
Primary Cell-Based Assay to Identify Agonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	neutrophil measurement	S1PR4	targetBased	0.22640684393981	13	217959	771
Primary Cell-Based Assay to Identify Antagonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	neutrophil measurement	S1PR4	targetBased	0.22640684393981	13	217959	569
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	neutrophil measurement	PPARG	targetBased	0.139978196356173	4	99314	335
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	neutrophil measurement	PPARG	targetBased	0.139978196356173	4	196176	782
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	neutrophil measurement	PPARG	targetBased	0.139978196356173	4	99314	390
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	neutrophil measurement	PPARG	targetBased	0.139978196356173	4	196177	811
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	neutrophil measurement	PPARG	targetBased	0.139978196356173	4	196176	670
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	neutrophil measurement	PPARG	targetBased	0.139978196356173	4	196177	519
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of 5-meCpG-binding domain protein 2 (MBD2)-DBD binding to methylated oligonucleotide	neutrophil measurement	MBD2	targetBased	0.124133011291483	5	369953	1149
qHTS Assay for NPC1 Promoter Activators	neutrophil measurement	NPC1	pathwayBased	0.177226831690445	9	320682	7575
Luminescence Cell-Based Primary HTS to Identify Inhibitors of A1 Apoptosis.	neutrophil measurement	BCL2L11_inhibitors	targetBased	0.16214467730286	9	325630	216
uHTS Luminescent assay for identification of inhibitors of NALP3 in yeast	neutrophil measurement	NLRP3	targetBased	0.17306526960857	11	330392	1295
Fluorescence-based primary biochemical high throughput screening assay to identify inhibitors of human diacylglycerol lipase, beta (DAGLB)	neutrophil measurement	DAGLB_inhibitors	targetBased	0.161046748266783	7	343468	202
HTS for Beta-2AR agonists via FAP method	neutrophil measurement	ADRB2_activators	targetBased	0.16680065824892	6	339297	1446
Primary HTS and Confirmation Assays for S1P1 Agonists and Agonism Potentiators	neutrophil measurement	S1PR1	targetBased	0.165448354599344	5	55710	315
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	neutrophil measurement	FGB_inhibitors	targetBased	0.180329667217648	4	369953	760
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	neutrophil measurement	FGB_inhibitors	targetBased	0.180329667217648	4	369953	498
Alphascreen assay for small molecules abrogating mHTT-CaM Interaction	neutrophil measurement	HTT	targetBased	0.133816872252241	4	189882	6790
Primary qHTS for Identification of Small Molecule Inhibitors of Huntingtin Promoter Activity	neutrophil measurement	HTT	targetBased	0.133816872252241	4	48068	449
qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Aggregate Formation (GFP)	neutrophil measurement	HTT	targetBased	0.133816872252241	4	220571	2380
qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Cytoprotection (ATP)	neutrophil measurement	HTT	targetBased	0.133816872252241	4	223611	305
Primary qHTS for Inhibitors of ATXN expression	neutrophil measurement	ATXN2_repressors	targetBased	0.120098235300211	6	358434	2554
Primary Cell-Based High-Throughput Screening to Identify Agonists of the Sphingosine 1-phosphate receptor 2 (S1P2)	neutrophil measurement	S1PR2	targetBased	0.147827188160112	6	96879	447
Primary Cell-Based High-Throughput Screening to Identify Antagonists of the Sphingosine 1-phosphate receptor 2 (S1P2)	neutrophil measurement	S1PR2	targetBased	0.147827188160112	6	96879	207
qHTS assay for re-activators of p53 using a Luc reporter	blood disease	TP53	pathwayBased	0.135869037210461	59	321427	201
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Nonpermissive Temperature	blood disease	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.135869037210461	59	54509	528
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Permissive Temperature	blood disease	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.135869037210461	59	54513	338
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature	blood disease	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.135869037210461	59	125394	1890
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Permissive Temperature	blood disease	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.135869037210461	59	124022	1156
Beta-Arrestin HTS for Positive Allosteric Modulators of the Human D2 Dopamine Receptor: Agonists	blood disease	D2_agonists	targetBased	0.207331243165371	6	359518	300
HTS Assay for Allosteric Agonists of the Human D2 Dopamine Receptor: Primary Screen for Agonists	blood disease	D2_agonists	targetBased	0.207331243165371	6	335652	1779
Beta-Arrestin HTS for Positive Allosteric Modulators of the Human D2 Dopamine Receptor: Potentiators	blood disease	D2_PAMs	targetBased	0.207331243165371	6	357537	806
HTS Assay for Positive Allosteric Modulators of the Human D2 Dopamine Receptor: Primary Screen for Potentiators	blood disease	D2_PAMs	targetBased	0.207331243165371	6	339887	1178
Beta-Arrestin HTS for Positive Allosteric Modulators of the Human D2 Dopamine Receptor: Antagonists	blood disease	D2_antagonists	targetBased	0.207331243165371	6	362274	1056
HTS Assay for Allosteric Antagonists of the Human D2 Dopamine Receptor: Primary Screen for Antagonists	blood disease	D2_antagonists	targetBased	0.207331243165371	6	336308	6862
qHTS of D3 Dopamine Receptor Antagonist: qHTS	blood disease	D3_antagonists	targetBased	0.201763871681875	4	364051	9106
qHTS of D3 Dopamine Receptor Agonist: qHTS	blood disease	D3_agonists	targetBased	0.201763871681875	4	407539	2380
qHTS of D3 Dopamine Receptor Potentiators: qHTS	blood disease	D3_PAMs	targetBased	0.201763871681875	4	407539	2380
HCS assay for microtubule stabilizers	blood disease	TUBB	targetBased	0.150095833992046	14	195821	1625
Identification of Molecular Probes that Activate MRP-1	basophil measurement	ABCC1_activators	targetBased	0.158697424312905	4	138717	842
HTS for Identification of VLA-4 Allosteric Modulators from MLPCN library	basophil measurement	ITGA4	targetBased	0.164774930419983	4	326888	645
Primary Cell-based High Throughput Screening assay for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA)	eosinophil measurement	RORA	pathwayBased	0.167661383357954	7	64908	979
Primary Cell-based High Throughput Screening assay for inhibitors of the Retinoic Acid Receptor-related orphan receptor A (RORA)	eosinophil measurement	RORA	pathwayBased	0.167661383357954	7	64908	278
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	eosinophil measurement	JAK2	targetBased	0.190886822514232	14	217959	2390
qHTS Assay for Inhibitors of the CtBP/E1A Interaction	eosinophil measurement	RBBP8	targetBased	0.119325357776129	5	335214	1652
Luminescence-based primary cell-based high throughput screening assay to identify activators of the Aryl Hydrocarbon Receptor (AHR)	eosinophil measurement	AHR_activators	targetBased	0.159119770880158	5	324747	7988
Fluorescence Biochemical Primary HTS to Identify Inhibitors of GASC-1 Activity	eosinophil measurement	KDM4C	targetBased	0.112867260193194	4	326066	228
High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Primary Screen	eosinophil measurement	NFKB1	pathwayBased	0.177871557840208	7	193265	3100
uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay	eosinophil measurement	NFKB1	pathwayBased	0.177871557840208	7	359244	3094
qHTS of IL-2 Activators	eosinophil measurement	IL2	targetBased	0.117157552473684	6	364617	238
HTS for Identification of VLA-4 Allosteric Modulators from MLPCN library	eosinophil measurement	ITGA4	targetBased	0.171365747000569	5	326888	645
Primary cell-based high throughput screening assay to measure STAT1 activation	eosinophil measurement	STAT1 activation	pathwayBased	0.158761644918857	4	195980	5134
Primary cell-based high throughput screening assay to measure STAT1 inhibition	eosinophil measurement	STAT1	targetBased	0.158761644918857	4	195980	695
uHTS identification of Caspase-8 TRAIL sensitizers in a luminesence assay	eosinophil measurement	TNFRSF10B	targetBased	0.121029549319942	4	363840	3764
Primary cell-based high-throughput screening assay for identification of compounds that inhibit/block inward-rectifying potassium ion channel Kir2.1	eosinophil measurement	KCNJ2	targetBased	0.149192224479104	5	305610	2592
Primary cell-based high-throughput screening for identification of compounds that inhibit/block calcium-activated chloride channels (TMEM16A)	eosinophil measurement	ANO1_inhibitors	targetBased	0.131152130740626	4	306502	3633
Primary cell-based high-throughput screening for identification of compounds that activate/potentiate calcium-activated chloride channels (TMEM16A)	eosinophil measurement	ANO1_activators	targetBased	0.131152130740626	4	335180	1022
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	eosinophil measurement	PPARG	targetBased	0.178730897009174	10	99314	335
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	eosinophil measurement	PPARG	targetBased	0.178730897009174	10	196176	782
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	eosinophil measurement	PPARG	targetBased	0.178730897009174	10	99314	390
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	eosinophil measurement	PPARG	targetBased	0.178730897009174	10	196177	811
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	eosinophil measurement	PPARG	targetBased	0.178730897009174	10	196176	670
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	eosinophil measurement	PPARG	targetBased	0.178730897009174	10	196177	519
qHTS for Activators of Integrin-Mediated Alleviation for Muscular Dystrophy	eosinophil measurement	CGA_integrin_activators	targetBased	0.124737016890887	5	345855	222
Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bfl-1	eosinophil measurement	BCL2A1_modulators	targetBased	0.164861729498291	8	194826	237
qHTS Assay for Identifying a Potential Treatment of Ataxia-Telangiectasia	eosinophil measurement	ATM_modulators	targetBased	0.140654979314363	6	322361	619
Luminescence Cell-Based Primary HTS to Identify Inhibitors of A1 Apoptosis.	eosinophil measurement	BCL2L11_inhibitors	targetBased	0.160290392272045	12	325630	216
Dyrk1 A HTS Measured in Biochemical System Using Plate Reader - 2124-01_Inhibitor_SinglePoint_HTS_Activity	eosinophil measurement	DYRK1A_inhibitors	targetBased	0.138391616063032	5	310014	1321
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb via a fluorescence resonance energy transfer (FRET) assay.	eosinophil measurement	RUNX1	targetBased	0.106156144505052	23	215667	993
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay.	eosinophil measurement	RUNX1	targetBased	0.106156144505052	23	218234	1620
qHTS Assay for Inhibitors of 15-hLO (15-human lipoxygenase)	eosinophil measurement	ALOX15_inhibitors	targetBased	0.248779523055908	24	73174	1034
HTS of Smad transcription factor inhibitors	eosinophil measurement	SMAD3	targetBased	0.188428786858302	18	88033	251
HTS for Beta-2AR agonists via FAP method	eosinophil measurement	ADRB2_activators	targetBased	0.181941714677825	11	339297	1446
Primary HTS and Confirmation Assays for S1P1 Agonists and Agonism Potentiators	eosinophil measurement	S1PR1	targetBased	0.165805298989825	11	55710	315
Primary biochemical high throughput screening assay to identify inhibitors of BCL2-related protein, long isoform (BCLXL).	eosinophil measurement	BCL2L1_modulators	targetBased	0.145307152089899	4	314998	2199
Primary qHTS for Inhibitors of ATXN expression	eosinophil measurement	ATXN2_repressors	targetBased	0.113789268938625	8	358434	2554
HTS for developing T Cell Immune Modulators	lymphocyte measurement	ITGAL	targetBased	0.152099927759827	8	326271	221
Identification of CBX7 inhibitors - Primary Alpha Screen	lymphocyte measurement	Chromobox protein homolog 7 inhibitors	targetBased	0.153874166828018	4	64999	724
High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Primary Screen	lymphocyte measurement	NFKB1	pathwayBased	0.158604541963189	7	193265	3100
uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay	lymphocyte measurement	NFKB1	pathwayBased	0.158604541963189	7	359244	3094
HTS for Identification of VLA-4 Allosteric Modulators from MLPCN library	lymphocyte measurement	ITGA4	targetBased	0.189787954251333	17	326888	645
MLPCN SirT-5 Measured in Biochemical System Using Imaging - 7044-01_Inhibitor_SinglePoint_HTS_Activity_Set5	lymphocyte measurement	SIRT5	targetBased	0.111750951816382	4	323507	3752
Primary Cell-Based Assay to Identify Agonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	lymphocyte measurement	S1PR4	targetBased	0.176540311822946	4	217959	771
Primary Cell-Based Assay to Identify Antagonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	lymphocyte measurement	S1PR4	targetBased	0.176540311822946	4	217959	569
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	lymphocyte measurement	PPARG	targetBased	0.141575358736432	6	99314	335
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	lymphocyte measurement	PPARG	targetBased	0.141575358736432	6	196176	782
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	lymphocyte measurement	PPARG	targetBased	0.141575358736432	6	99314	390
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	lymphocyte measurement	PPARG	targetBased	0.141575358736432	6	196177	811
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	lymphocyte measurement	PPARG	targetBased	0.141575358736432	6	196176	670
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	lymphocyte measurement	PPARG	targetBased	0.141575358736432	6	196177	519
qHTS Assay for Identifying a Potential Treatment of Ataxia-Telangiectasia	lymphocyte measurement	ATM_modulators	targetBased	0.171184636915294	5	322361	619
Luminescence Cell-Based Primary HTS to Identify Inhibitors of A1 Apoptosis.	monocyte measurement	BCL2L11_inhibitors	targetBased	0.178424351360473	21	325630	216
Luminescence Cell-Based Primary HTS to Identify Inhibitors of A1 Apoptosis.	lymphocyte measurement	BCL2L11_inhibitors	targetBased	0.166765881229284	13	325630	216
uHTS Fluorescent assay for identification of inhibitors of hexokinase domain containing I (HKDC1)	lymphocyte measurement	HKDC1	targetBased	0.167541764889662	5	340696	540
HTS identification of compounds inhibiting the binding of CD11b/CD18 to fibrinogen via a luminescence assay.	lymphocyte measurement	ITGB2	targetBased	0.149622826381854	4	92518	501
Primary HTS assay for chemical inhibitors of TNF alpha stimulated VCAM1 expression	lymphocyte measurement	VCAM1_expression	targetBased	0.174661330679796	8	94498	457
Fluorescence-based primary biochemical high throughput screening assay to identify inhibitors of human diacylglycerol lipase, beta (DAGLB)	lymphocyte measurement	DAGLB_inhibitors	targetBased	0.160574325168838	6	343468	202
Primary HTS and Confirmation Assays for S1P1 Agonists and Agonism Potentiators	lymphocyte measurement	S1PR1	targetBased	0.195045563695402	21	55710	315
Luminescence-based primary cell-based high throughput screening assay to identify activators of the Aryl Hydrocarbon Receptor (AHR)	monocyte measurement	AHR_activators	targetBased	0.145114887722151	4	324747	7988
High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Primary Screen	monocyte measurement	NFKB1	pathwayBased	0.169555563158379	5	193265	3100
uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay	monocyte measurement	NFKB1	pathwayBased	0.169555563158379	5	359244	3094
HTS for Identification of VLA-4 Allosteric Modulators from MLPCN library	monocyte measurement	ITGA4	targetBased	0.188106360178515	18	326888	645
uHTS for the identification of compounds that potentiate TRAIL-induced apoptosis of cancer cells	monocyte measurement	TNFSF10	targetBased	0.16590631999203	5	217035	883
qHTS Assay for Inhibitors of BAZ2B	monocyte measurement	BAZ2B_modulators	targetBased	0.153572330372376	4	356826	15709
Primary Cell-Based Assay to Identify Agonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	monocyte measurement	S1PR4	targetBased	0.221935267932537	11	217959	771
Primary Cell-Based Assay to Identify Antagonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	monocyte measurement	S1PR4	targetBased	0.221935267932537	11	217959	569
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	monocyte measurement	PPARG	targetBased	0.133796104188645	5	99314	335
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	monocyte measurement	PPARG	targetBased	0.133796104188645	5	196176	782
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	monocyte measurement	PPARG	targetBased	0.133796104188645	5	99314	390
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	monocyte measurement	PPARG	targetBased	0.133796104188645	5	196177	811
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	monocyte measurement	PPARG	targetBased	0.133796104188645	5	196176	670
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma)	monocyte measurement	PPARG	targetBased	0.133796104188645	5	196177	519
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb via a fluorescence resonance energy transfer (FRET) assay.	monocyte measurement	RUNX1	targetBased	0.113236775921982	8	215667	993
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay.	monocyte measurement	RUNX1	targetBased	0.113236775921982	8	218234	1620
Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bfl-1	monocyte measurement	BCL2A1_modulators	targetBased	0.165499710092157	10	194826	237
qHTS Assay for NPC1 Promoter Activators	monocyte measurement	NPC1	pathwayBased	0.134760572990049	4	320682	7575
Fluorescence-based primary biochemical high throughput screening assay to identify inhibitors of human diacylglycerol lipase, beta (DAGLB)	monocyte measurement	DAGLB_inhibitors	targetBased	0.16777295623607	7	343468	202
Primary qHTS for Inhibitors of ATXN expression	lymphocyte measurement	ATXN2_repressors	targetBased	0.132756964548693	9	358434	2554
Primary HTS Assay for S1P3 Antagonists	lymphocyte measurement	S1PR3	targetBased	0.155328574703874	7	169141	462
HTS for developing T Cell Immune Modulators	monocyte measurement	ITGAL	targetBased	0.13217983972285	4	326271	221
Primary qHTS for Inhibitors of ATXN expression	monocyte measurement	ATXN2_repressors	targetBased	0.105475119878582	5	358434	2554
Primary Cell-Based High-Throughput Screening to Identify Agonists of the Sphingosine 1-phosphate receptor 2 (S1P2)	monocyte measurement	S1PR2	targetBased	0.187007574479859	4	96879	447
Primary Cell-Based High-Throughput Screening to Identify Antagonists of the Sphingosine 1-phosphate receptor 2 (S1P2)	monocyte measurement	S1PR2	targetBased	0.187007574479859	4	96879	207
HTS to identify compounds that promote myeloid differentiation with MLPCN compound set	monocyte measurement	HOXA9	pathwayBased	0.124872814902845	5	358556	3721
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of myeloid cell leukemia sequence 1 (MCL1) interactions with BIM-BH3 peptide.	monocyte measurement	MCL1	targetBased	0.100410764729757	10	314998	2139
uHTS of Mcl-1/Bid interaction inhibitors	monocyte measurement	MCL1	targetBased	0.100410764729757	10	218602	2129
uHTS of Mcl-1/Noxa interaction inhibitors	monocyte measurement	MCL1	targetBased	0.100410764729757	10	217330	3334
Primary HTS assay for chemical inhibitors of TNF alpha stimulated VCAM1 expression	monocyte measurement	VCAM1_expression	targetBased	0.15331081627866	6	94498	457
Small-molecule inhibitors of ST2 (IL1RL1)	eosinophil measurement	IL1RL1	targetBased	0.182419843595803	18	75924	1804
Primary Cell-Based Assay to Identify Agonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	eosinophil measurement	S1PR4	targetBased	0.233389293294673	11	217959	771
Primary Cell-Based Assay to Identify Antagonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4)	eosinophil measurement	S1PR4	targetBased	0.233389293294673	11	217959	569
uHTS Luminescent assay for identification of inhibitors of Sentrin-specific protease 7 (SENP7)	eosinophil measurement	SENP7	targetBased	0.134522187669021	4	331670	4902
Primary HTS Assay for S1P3 Antagonists	monocyte measurement	S1PR3	targetBased	0.197882138766867	15	169141	462
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	Abnormal thrombosis	JAK2	targetBased	0.103063295079171	54	217959	2390
qHTS for Inhibitors of Cell Surface uPA Generation	Abnormal thrombosis	PLAU	targetBased	0.137451343549571	13	325247	1021
Thrombin 1536 HTS	Abnormal thrombosis	F2_modulation	targetBased	0.261803318634528	391	217233	557
Factor XIa 1536 HTS	Abnormality of blood and blood-forming tissues	F11_modulation	targetBased	0.233005818582927	59	218707	302
HTS of Estrogen Receptor- alpha Coactivator Binding inhibitors	Abnormality of blood and blood-forming tissues	ESR1_inhibitors	targetBased	0.212115879028621	74	86095	1442
HTS of Estrogen Receptor- alpha Coactivator Binding Potentiators	Abnormality of blood and blood-forming tissues	ESR1_modulators	targetBased	0.212115879028621	74	86095	1151
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	Abnormality of blood and blood-forming tissues	JAK2	targetBased	0.2537900371911	601	217959	2390
qHTS for Inhibitors of TGF-b	Abnormality of blood and blood-forming tissues	TGFB1	pathwayBased	0.182432642967463	136	403345	4970
Toxoplasma gondii inhibition HTS in the presence of IFN-y	Abnormality of blood and blood-forming tissues	IFNG	targetBased	0.155618676199325	240	67275	2509
qHTS for Inhibitors of Cell Surface uPA Generation	Abnormality of blood and blood-forming tissues	PLAU	targetBased	0.137508469480126	18	325247	1021
Factor XIIa 1536 HTS	Abnormality of blood and blood-forming tissues	F12_modulation	targetBased	0.192934012799045	8	217430	649
qHTS assay for re-activators of p53 using a Luc reporter	Abnormality of blood and blood-forming tissues	TP53	pathwayBased	0.130250014236272	72	321427	201
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Nonpermissive Temperature	Abnormality of blood and blood-forming tissues	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.130250014236272	72	54509	528
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Permissive Temperature	Abnormality of blood and blood-forming tissues	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.130250014236272	72	54513	338
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature	Abnormality of blood and blood-forming tissues	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.130250014236272	72	125394	1890
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Permissive Temperature	Abnormality of blood and blood-forming tissues	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.130250014236272	72	124022	1156
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb via a fluorescence resonance energy transfer (FRET) assay.	Abnormality of blood and blood-forming tissues	RUNX1	targetBased	0.244202675967087	116	215667	993
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay.	Abnormality of blood and blood-forming tissues	RUNX1	targetBased	0.244202675967087	116	218234	1620
HTS for Beta-2AR agonists via FAP method	Abnormality of blood and blood-forming tissues	ADRB2_activators	targetBased	0.210163242859303	11	339297	1446
Glucocerebrosidase	Abnormality of blood and blood-forming tissues	GBA1	targetBased	0.186341628989345	20	48118	549
Fluorescence-based primary cell-based high throughput screening assay to identify agonists of the Oxytocin Receptor (OXTR).	Abnormality of blood and blood-forming tissues	OXTR	targetBased	0.219732953078622	38	324747	1043
Allosteric Agonists of the Human D1 Dopamine Receptor: qHTS	Abnormality of blood and blood-forming tissues	D1_activators	targetBased	0.218345101384324	18	361330	3713
Allosteric Modulators of D1 Receptors: Primary Screen	Abnormality of blood and blood-forming tissues	D1	targetBased	0.218345101384324	18	57705	3413
Antagonist of Human D 1 Dopamine Receptor: qHTS	Abnormality of blood and blood-forming tissues	D1_inhibitors	targetBased	0.218345101384324	18	355805	11440
HTS Assay for Compounds that Act as Agonists of the Vanilloid Receptor 1	Abnormality of blood and blood-forming tissues	TRPV1	targetBased	0.181374683889192	4	316642	617
qHTS for Inhibitors of TGF-b	Abnormal erythrocyte morphology	TGFB1	pathwayBased	0.176338676413271	8	403345	4970
Inhibitors of the vitamin D receptor (VDR): qHTS	Abnormal erythrocyte morphology	VDR	targetBased	0.198238437167499	4	394050	3624
Toxoplasma gondii inhibition HTS in the presence of IFN-y	Abnormal erythrocyte morphology	IFNG	targetBased	0.155168040901913	48	67275	2509
HTS of Estrogen Receptor- alpha Coactivator Binding inhibitors	Abnormal bleeding	ESR1_inhibitors	targetBased	0.171873631556554	4	86095	1442
HTS of Estrogen Receptor- alpha Coactivator Binding Potentiators	Abnormal bleeding	ESR1_modulators	targetBased	0.171873631556554	4	86095	1151
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	Abnormality of coagulation	FGB_inhibitors	targetBased	0.195073005131717	11	369953	760
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	Abnormality of coagulation	FGB_inhibitors	targetBased	0.195073005131717	11	369953	498
Inhibitors of the vitamin D receptor (VDR): qHTS	Abnormality of blood and blood-forming tissues	VDR	targetBased	0.200086038386424	10	394050	3624
Counterscreen for Oxytocin Receptor (OXTR) agonists: Fluorescence-based primary cell-based high throughput assay to identify agonists of the vasopressin 1 receptor (V1R)	Abnormal blood sodium concentration	AVPR1A_agonists	targetBased	0.199404944071193	8	324747	813
qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide	Abnormal blood ion concentration	Menin-MLL_inhibitors	targetBased	0.125420660011957	6	263421	615
qHTS for PTHR1 Agonists: Primary Screen	Abnormal blood ion concentration	PTH1R	targetBased	0.142503255966717	4	405685	308
Counterscreen for Oxytocin Receptor (OXTR) agonists: Fluorescence-based primary cell-based high throughput assay to identify agonists of the vasopressin 1 receptor (V1R)	Abnormal blood ion concentration	AVPR1A_agonists	targetBased	0.199404944071193	8	324747	813
HTS for Beta-2AR agonists via FAP method	Abnormal blood ion concentration	ADRB2_activators	targetBased	0.184534067004865	6	339297	1446
qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS	Abnormal blood ion concentration	GNAS	targetBased	0.124885591367969	10	334825	423
qHTS for Antagonists of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS	Abnormal blood ion concentration	GNAS	targetBased	0.124885591367969	10	337446	1356
Inhibitors of the vitamin D receptor (VDR): qHTS	Abnormal blood ion concentration	VDR	targetBased	0.217674093979415	28	394050	3624
Inhibitors of the vitamin D receptor (VDR): qHTS	Abnormal blood phosphate concentration	VDR	targetBased	0.135235601324715	10	394050	3624
qHTS Assay to Identify Small Molecule Activators of BRCA1 Expression	congenital anemia	BRCA1 activation	pathwayBased	0.302802832580705	198	376029	3978
uHTS identification of DNMT1 inhibitors in a Fluorescent Molecular Beacon assay	inherited bleeding disorder, platelet-type	DNMT1	targetBased	0.101916123224869	4	359244	2975
qHTS for Inhibitors of Cell Surface uPA Generation	inherited bleeding disorder, platelet-type	PLAU	targetBased	0.240289252620454	46	325247	1021
qHTS assay for re-activators of p53 using a Luc reporter	pure red-cell aplasia	TP53	pathwayBased	0.15586421120356	45	321427	201
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Nonpermissive Temperature	pure red-cell aplasia	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.15586421120356	45	54509	528
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Permissive Temperature	pure red-cell aplasia	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.15586421120356	45	54513	338
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature	pure red-cell aplasia	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.15586421120356	45	125394	1890
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Permissive Temperature	pure red-cell aplasia	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.15586421120356	45	124022	1156
qHTS Assay to Identify Small Molecule Activators of BRCA1 Expression	inherited aplastic anemia	BRCA1 activation	pathwayBased	0.302802832580705	198	376029	3978
qHTS assay for re-activators of p53 using a Luc reporter	inherited aplastic anemia	TP53	pathwayBased	0.158572907624369	119	321427	201
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Nonpermissive Temperature	inherited aplastic anemia	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.158572907624369	119	54509	528
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Permissive Temperature	inherited aplastic anemia	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.158572907624369	119	54513	338
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature	inherited aplastic anemia	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.158572907624369	119	125394	1890
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Permissive Temperature	inherited aplastic anemia	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.158572907624369	119	124022	1156
Factor XIIa 1536 HTS	coagulation protein disease	F12_modulation	targetBased	0.295492038584081	38	217430	649
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	coagulation protein disease	FGB_inhibitors	targetBased	0.305997633725781	90	369953	760
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	coagulation protein disease	FGB_inhibitors	targetBased	0.305997633725781	90	369953	498
uHTS identification of DNMT1 inhibitors in a Fluorescent Molecular Beacon assay	hemorrhagic disease	DNMT1	targetBased	0.101916123224869	4	359244	2975
Factor XIIa 1536 HTS	hemorrhagic disease	F12_modulation	targetBased	0.295608687955891	41	217430	649
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	blood platelet disease	JAK2	targetBased	0.256237864274756	666	217959	2390
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of the interaction of the Ras and Rab interactor 1 protein (Rin1) and the c-abl oncogene 1, non-receptor tyrosine kinase (Abl)	blood platelet disease	ABL1_interaction	targetBased	0.103308372569967	87	359207	1432
EZH2/PRC2 methyltransferase inhibitors Measured in Biochemical System Using Plate Reader - 2125-01_Inhibitor_SinglePoint_HTS_Activity	blood platelet disease	EZH2_inhibitors	targetBased	0.128407632407164	13	57013	201
Inhibitors of the vitamin D receptor (VDR): qHTS	blood platelet disease	VDR	targetBased	0.138074493352363	4	394050	3624
uHTS identification of DNMT1 inhibitors in a Fluorescent Molecular Beacon assay	blood platelet disease	DNMT1	targetBased	0.101916123224869	4	359244	2975
qHTS Assay to Identify Small Molecule Activators of BRCA1 Expression	anemia	BRCA1 activation	pathwayBased	0.302850233678261	205	376029	3978
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	anemia	JAK2	targetBased	0.276954558225098	362	217959	2390
Toxoplasma gondii inhibition HTS in the presence of IFN-y	anemia	IFNG	targetBased	0.145570005143111	138	67275	2509
Flow Cytometric HTS Screen for inhibitors of the ABC transporter ABCB6 for MLPCN Compound Set	anemia	ABCB6_inhibitors	targetBased	0.250231571451569	8	362098	692
Primary biochemical high throughput screening assay to identify inhibitors of BCL2-related protein, long isoform (BCLXL).	anemia	BCL2L1_modulators	targetBased	0.130745975497781	22	314998	2199
Fluorescence Cell-Free Homogeneous Primary HTS to Identify Inhibitors of Histone Deacetylase 3	anemia	HDAC3	targetBased	0.148117552783609	17	318291	483
uHTS identification of DNMT1 inhibitors in a Fluorescent Molecular Beacon assay	purpura	DNMT1	targetBased	0.101916123224869	4	359244	2975
Flow Cytometric HTS Screen for inhibitors of the ABC transporter ABCB6 for MLPCN Compound Set	familial hemolytic anemia	ABCB6_inhibitors	targetBased	0.250164253553594	7	362098	692
Flow Cytometric HTS Screen for inhibitors of the ABC transporter ABCB6 for MLPCN Compound Set	normocytic anemia	ABCB6_inhibitors	targetBased	0.250164253553594	7	362098	692
qHTS Assay to Identify Small Molecule Activators of BRCA1 Expression	congenital hematological disorder	BRCA1 activation	pathwayBased	0.302802832580705	198	376029	3978
Factor XIa 1536 HTS	congenital hematological disorder	F11_modulation	targetBased	0.30945853000873	183	218707	302
uHTS identification of HIF-2a Inhibitors in a luminesence assay	congenital hematological disorder	HIF-2a_inhibitors	targetBased	0.14066046046453	6	363840	2624
Factor XIIa 1536 HTS	congenital hematological disorder	F12_modulation	targetBased	0.295294207352424	36	217430	649
Thrombin 1536 HTS	congenital hematological disorder	F2_modulation	targetBased	0.29296089563512	153	217233	557
Thrombin 1536 HTS	congenital vitamin K-dependent coagulation factors deficiency	F2_modulation	targetBased	0.292872806915199	149	217233	557
qHTS Assay to Identify Small Molecule Activators of BRCA1 Expression	aplastic anemia	BRCA1 activation	pathwayBased	0.302802832580705	198	376029	3978
Fluorescence Cell-Free Homogeneous Primary HTS to Identify Inhibitors of Histone Deacetylase 3	aplastic anemia	HDAC3	targetBased	0.146485558543147	4	318291	483
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	beta-thalassemia and related diseases	JAK2	targetBased	0.148925004270033	24	217959	2390
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb via a fluorescence resonance energy transfer (FRET) assay.	syndromic constitutional thrombocytopenia	RUNX1	targetBased	0.127032549019444	6	215667	993
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay.	syndromic constitutional thrombocytopenia	RUNX1	targetBased	0.127032549019444	6	218234	1620
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	inherited hemoglobinopathy	JAK2	targetBased	0.149728488513643	62	217959	2390
ROC1-CUL1 CTD Inhibitor di-Ub FRET Primary HTS Screen	inherited hemoglobinopathy	RBX1	targetBased	0.166303319306276	5	143816	859
Inhibitors of the vitamin D receptor (VDR): qHTS	inherited hemoglobinopathy	VDR	targetBased	0.104776545816967	10	394050	3624
Luminescence-based cell-based primary high throughput screening assay to identify agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors	inherited hemoglobinopathy	OPRM1	targetBased	0.210237856346993	8	335239	991
Luminescence-based cell-based primary high throughput screening assay to identify inverse agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors	inherited hemoglobinopathy	OPRM1	targetBased	0.210237856346993	8	335239	695
qHTS for Inhibitors of TGF-b	inherited hemoglobinopathy	TGFB1	pathwayBased	0.189884931661064	14	403345	4970
Flow Cytometric HTS Screen for inhibitors of the ABC transporter ABCB6 for MLPCN Compound Set	hereditary stomatocytosis	ABCB6_inhibitors	targetBased	0.250164253553594	7	362098	692
qHTS for Inhibitors of Cell Surface uPA Generation	alpha granule disease	PLAU	targetBased	0.239880610836013	45	325247	1021
Factor XIa 1536 HTS	inherited blood coagulation disorder	F11_modulation	targetBased	0.309817469351117	195	218707	302
uHTS identification of DNMT1 inhibitors in a Fluorescent Molecular Beacon assay	inherited blood coagulation disorder	DNMT1	targetBased	0.101916123224869	4	359244	2975
Factor XIIa 1536 HTS	inherited blood coagulation disorder	F12_modulation	targetBased	0.295602432867867	40	217430	649
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb via a fluorescence resonance energy transfer (FRET) assay.	inherited blood coagulation disorder	RUNX1	targetBased	0.299126719634149	1568	215667	993
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay.	inherited blood coagulation disorder	RUNX1	targetBased	0.299126719634149	1568	218234	1620
Thrombin 1536 HTS	inherited blood coagulation disorder	F2_modulation	targetBased	0.302328483279102	264	217233	557
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	erythrocyte disorder	JAK2	targetBased	0.15207670612115	64	217959	2390
ROC1-CUL1 CTD Inhibitor di-Ub FRET Primary HTS Screen	erythrocyte disorder	RBX1	targetBased	0.166438556154887	6	143816	859
qHTS for Inhibitors of TGF-b	erythrocyte disorder	TGFB1	pathwayBased	0.197702455854079	99	403345	4970
Inhibitors of the vitamin D receptor (VDR): qHTS	erythrocyte disorder	VDR	targetBased	0.104853443317412	13	394050	3624
Luminescence-based cell-based primary high throughput screening assay to identify agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors	erythrocyte disorder	OPRM1	targetBased	0.210812612953588	9	335239	991
Luminescence-based cell-based primary high throughput screening assay to identify inverse agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors	erythrocyte disorder	OPRM1	targetBased	0.210812612953588	9	335239	695
HTS Assay for Compounds that Act as Agonists of the Vanilloid Receptor 1	erythrocyte disorder	TRPV1	targetBased	0.196808373542366	8	316642	617
Fluorescence-based cell-based primary high throughput screening assay to identify inhibitors of TLR9-MyD88 binding.	erythrocyte disorder	TLR9	targetBased	0.214048065522134	72	343468	734
ROC1-CUL1 CTD Inhibitor di-Ub FRET Primary HTS Screen	hemoglobinopathy	RBX1	targetBased	0.166303319306276	5	143816	859
qHTS for Inhibitors of TGF-b	hemoglobinopathy	TGFB1	pathwayBased	0.189884931661064	14	403345	4970
Inhibitors of the vitamin D receptor (VDR): qHTS	hemoglobinopathy	VDR	targetBased	0.104776545816967	10	394050	3624
Luminescence-based cell-based primary high throughput screening assay to identify agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors	hemoglobinopathy	OPRM1	targetBased	0.210237856346993	8	335239	991
Luminescence-based cell-based primary high throughput screening assay to identify inverse agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors	hemoglobinopathy	OPRM1	targetBased	0.210237856346993	8	335239	695
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	hemoglobinopathy	JAK2	targetBased	0.149728488513643	62	217959	2390
qHTS for Inhibitors of Cell Surface uPA Generation	inherited thrombocytopenia	PLAU	targetBased	0.239880610836013	45	325247	1021
uHTS identification of DNMT1 inhibitors in a Fluorescent Molecular Beacon assay	inherited thrombocytopenia	DNMT1	targetBased	0.101916123224869	4	359244	2975
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb via a fluorescence resonance energy transfer (FRET) assay.	inherited thrombocytopenia	RUNX1	targetBased	0.129075629581349	35	215667	993
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay.	inherited thrombocytopenia	RUNX1	targetBased	0.129075629581349	35	218234	1620
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	disease related to hematopoietic stem cell transplant	JAK2	targetBased	0.208045754409034	53	217959	2390
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of the interaction of the Ras and Rab interactor 1 protein (Rin1) and the c-abl oncogene 1, non-receptor tyrosine kinase (Abl)	disease related to hematopoietic stem cell transplant	ABL1_interaction	targetBased	0.110127263782583	21	359207	1432
Primary biochemical high-throughput screening assay for inhibitors of Rho kinase 2 (Rhok2)	disease related to hematopoietic stem cell transplant	ROCK2	targetBased	0.18535902535822	16	59788	212
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	Rare genetic hematologic disease	JAK2	targetBased	0.154410140150091	79	217959	2390
ROC1-CUL1 CTD Inhibitor di-Ub FRET Primary HTS Screen	Rare genetic hematologic disease	RBX1	targetBased	0.166168082457666	5	143816	859
qHTS for Inhibitors of TGF-b	Rare genetic hematologic disease	TGFB1	pathwayBased	0.194162384029073	31	403345	4970
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb via a fluorescence resonance energy transfer (FRET) assay.	Rare genetic hematologic disease	RUNX1	targetBased	0.131697505450641	54	215667	993
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay.	Rare genetic hematologic disease	RUNX1	targetBased	0.131697505450641	54	218234	1620
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	Rare genetic hematologic disease	FGB_inhibitors	targetBased	0.283456235742453	10	369953	760
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	Rare genetic hematologic disease	FGB_inhibitors	targetBased	0.283456235742453	10	369953	498
Thrombin 1536 HTS	Rare genetic hematologic disease	F2_modulation	targetBased	0.283145242961231	59	217233	557
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	Rare constitutional anemia	JAK2	targetBased	0.149648857556893	51	217959	2390
ROC1-CUL1 CTD Inhibitor di-Ub FRET Primary HTS Screen	Rare constitutional anemia	RBX1	targetBased	0.166168082457666	5	143816	859
qHTS for Inhibitors of TGF-b	Rare constitutional anemia	TGFB1	pathwayBased	0.192185173505536	13	403345	4970
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb via a fluorescence resonance energy transfer (FRET) assay.	Rare genetic coagulation disorder	RUNX1	targetBased	0.131339412407508	26	215667	993
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay.	Rare genetic coagulation disorder	RUNX1	targetBased	0.131339412407508	26	218234	1620
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	Rare genetic coagulation disorder	FGB_inhibitors	targetBased	0.283042061010527	8	369953	760
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	Rare genetic coagulation disorder	FGB_inhibitors	targetBased	0.283042061010527	8	369953	498
Thrombin 1536 HTS	Rare genetic coagulation disorder	F2_modulation	targetBased	0.283144223778482	52	217233	557
qHTS assay for re-activators of p53 using a Luc reporter	Rare constitutional medullar aplasia	TP53	pathwayBased	0.156054892279715	19	321427	201
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Nonpermissive Temperature	Rare constitutional medullar aplasia	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.156054892279715	19	54509	528
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53 Null Cells at the Permissive Temperature	Rare constitutional medullar aplasia	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.156054892279715	19	54513	338
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature	Rare constitutional medullar aplasia	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.156054892279715	19	125394	1890
qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Permissive Temperature	Rare constitutional medullar aplasia	nonSmallCellLungCarcinomaWithP53Mutations	targetBased	0.156054892279715	19	124022	1156
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb via a fluorescence resonance energy transfer (FRET) assay.	Rare hemorrhagic disorder due to a constitutional thrombocytopenia	RUNX1	targetBased	0.130926799981329	9	215667	993
uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay.	Rare hemorrhagic disorder due to a constitutional thrombocytopenia	RUNX1	targetBased	0.130926799981329	9	218234	1620
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	Rare hemorrhagic disorder due to a constitutional coagulation factors defect	FGB_inhibitors	targetBased	0.283042061010527	8	369953	760
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	Rare hemorrhagic disorder due to a constitutional coagulation factors defect	FGB_inhibitors	targetBased	0.283042061010527	8	369953	498
Thrombin 1536 HTS	Rare hemorrhagic disorder due to a constitutional coagulation factors defect	F2_modulation	targetBased	0.283106497702718	43	217233	557

Some of these associations have also gone through clinical trials, as those in the graph below.

Find clinical trials details in table. Use scroll bar or search funtion to select specific drugs, molecular targets or diseases.

BioAssay Name	program	gene	protName	diseaseName	molname	assayMode	clinicalPhase	clinicalStatus	studyStartDate	url	score	variantEffect	directionOnTrait	studyStopReason
ROC1-CUL1 CTD Inhibitor di-Ub FRET Primary HTS Screen	RBX1	RBX1	E3 ubiquitin-protein ligase RBX1	Thalassemia	THALIDOMIDE	targetBased	2	Unknown status	02/05/2017	https://clinicaltrials.gov/study/NCT03184844	0.2	LoF	protect
ROC1-CUL1 CTD Inhibitor di-Ub FRET Primary HTS Screen	RBX1	RBX1	E3 ubiquitin-protein ligase RBX1	Thalassemia	THALIDOMIDE	targetBased	4	Recruiting	01/11/2023	https://clinicaltrials.gov/study/NCT06299670	1	LoF	protect
ROC1-CUL1 CTD Inhibitor di-Ub FRET Primary HTS Screen	RBX1	RBX1	E3 ubiquitin-protein ligase RBX1	Thalassemia	THALIDOMIDE	targetBased	2	Completed	01/01/2018	https://clinicaltrials.gov/study/NCT03651102	0.2	LoF	protect
ROC1-CUL1 CTD Inhibitor di-Ub FRET Primary HTS Screen	RBX1	RBX1	E3 ubiquitin-protein ligase RBX1	Thalassemia	THALIDOMIDE	targetBased	2	Unknown status	01/09/2016	https://clinicaltrials.gov/study/NCT02995707	0.2	LoF	protect
Luminescence-based cell-based primary high throughput screening assay to identify agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors	OPRM1	OPRM1	Mu-type opioid receptor	blood coagulation disease	MORPHINE	targetBased	2	Completed	01/01/2016	https://clinicaltrials.gov/study/NCT02622126	0.2	GoF	protect
Luminescence-based cell-based primary high throughput screening assay to identify inverse agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors	OPRM1	OPRM1	Mu-type opioid receptor	blood coagulation disease	MORPHINE	targetBased	2	Completed	01/01/2016	https://clinicaltrials.gov/study/NCT02622126	0.2	GoF	protect
Luminescence-based cell-based primary high throughput screening assay to identify agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors	OPRM1	OPRM1	Mu-type opioid receptor	hemorrhage	MORPHINE	targetBased	2	Completed	01/01/2016	https://clinicaltrials.gov/study/NCT02622126	0.2	GoF	protect
Luminescence-based cell-based primary high throughput screening assay to identify inverse agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors	OPRM1	OPRM1	Mu-type opioid receptor	hemorrhage	MORPHINE	targetBased	2	Completed	01/01/2016	https://clinicaltrials.gov/study/NCT02622126	0.2	GoF	protect
HTS of Estrogen Receptor- alpha Coactivator Binding inhibitors	ESR1_inhibitors	ESR1	Estrogen receptor, Estrogen receptor	hemorrhage	TAMOXIFEN	targetBased	4	Withdrawn	01/05/2022	https://clinicaltrials.gov/study/NCT04933240	1		protect	Anticipated funding was not received
HTS of Estrogen Receptor- alpha Coactivator Binding Potentiators	ESR1_modulators	ESR1	Estrogen receptor, Estrogen receptor	hemorrhage	TAMOXIFEN	targetBased	4	Withdrawn	01/05/2022	https://clinicaltrials.gov/study/NCT04933240	1		protect	Anticipated funding was not received
HTS of Estrogen Receptor- alpha Coactivator Binding inhibitors	ESR1_inhibitors	ESR1	Estrogen receptor, Estrogen receptor	hemorrhage	TAMOXIFEN	targetBased	4	Completed	20/01/2017	https://clinicaltrials.gov/study/NCT02903121	1		protect
HTS of Estrogen Receptor- alpha Coactivator Binding Potentiators	ESR1_modulators	ESR1	Estrogen receptor, Estrogen receptor	hemorrhage	TAMOXIFEN	targetBased	4	Completed	20/01/2017	https://clinicaltrials.gov/study/NCT02903121	1		protect
HCS assay for microtubule stabilizers	TUBB	TUBB	Tubulin beta chain	anemia (phenotype)	PACLITAXEL	targetBased	3	Terminated	01/02/2004	https://clinicaltrials.gov/study/NCT00189371	0.7	LoF	protect
HTS Assay for Compounds that Act as Agonists of the Vanilloid Receptor 1	TRPV1	TRPV1	Transient receptor potential cation channel subfamily V member 1	hemorrhage	ACETAMINOPHEN	targetBased	3	Unknown status	01/10/2016	https://clinicaltrials.gov/study/NCT03024814	0.7		protect
HTS Assay for Compounds that Act as Agonists of the Vanilloid Receptor 1	TRPV1	TRPV1	Transient receptor potential cation channel subfamily V member 1	hemorrhage	ACETAMINOPHEN	targetBased	4	Unknown status	01/12/2013	https://clinicaltrials.gov/study/NCT02238288	1		protect
HTS Assay for Compounds that Act as Agonists of the Vanilloid Receptor 1	TRPV1	TRPV1	Transient receptor potential cation channel subfamily V member 1	hemorrhage	ACETAMINOPHEN	targetBased	2	Completed	03/05/2012	https://clinicaltrials.gov/study/NCT01605903	0.2		protect
HTS Assay for Compounds that Act as Agonists of the Vanilloid Receptor 1	TRPV1	TRPV1	Transient receptor potential cation channel subfamily V member 1	hemorrhage	ACETAMINOPHEN	targetBased	4	Completed	01/08/2000	https://clinicaltrials.gov/study/NCT01073670	1		protect
HTS of Estrogen Receptor- alpha Coactivator Binding inhibitors	ESR1_inhibitors	ESR1	Estrogen receptor, Estrogen receptor	hemorrhage	ESTRADIOL	targetBased	4	Withdrawn	01/05/2022	https://clinicaltrials.gov/study/NCT04933240	1	GoF	protect	Anticipated funding was not received
HTS of Estrogen Receptor- alpha Coactivator Binding Potentiators	ESR1_modulators	ESR1	Estrogen receptor, Estrogen receptor	hemorrhage	ESTRADIOL	targetBased	4	Withdrawn	01/05/2022	https://clinicaltrials.gov/study/NCT04933240	1	GoF	protect	Anticipated funding was not received
HTS of Estrogen Receptor- alpha Coactivator Binding inhibitors	ESR1_inhibitors	ESR1	Estrogen receptor, Estrogen receptor	thrombophilia	ESTRADIOL	targetBased	4	Terminated	01/03/2016	https://clinicaltrials.gov/study/NCT03531437	1	GoF	protect	problem with recruiting participants
HTS of Estrogen Receptor- alpha Coactivator Binding Potentiators	ESR1_modulators	ESR1	Estrogen receptor, Estrogen receptor	thrombophilia	ESTRADIOL	targetBased	4	Terminated	01/03/2016	https://clinicaltrials.gov/study/NCT03531437	1	GoF	protect	problem with recruiting participants
HTS of Estrogen Receptor- alpha Coactivator Binding inhibitors	ESR1_inhibitors	ESR1	Estrogen receptor, Estrogen receptor	Microscopic hematuria	ESTRADIOL	targetBased	4	Unknown status	01/12/2016	https://clinicaltrials.gov/study/NCT03033160	1	GoF	protect
HTS of Estrogen Receptor- alpha Coactivator Binding Potentiators	ESR1_modulators	ESR1	Estrogen receptor, Estrogen receptor	Microscopic hematuria	ESTRADIOL	targetBased	4	Unknown status	01/12/2016	https://clinicaltrials.gov/study/NCT03033160	1	GoF	protect
HTS for Beta-2AR agonists via FAP method	ADRB2_activators	ADRB2	Beta-2 adrenergic receptor	Hemoptysis	EPINEPHRINE	targetBased	2	Completed	01/07/2017	https://clinicaltrials.gov/study/NCT03126968	0.2	GoF	protect
HTS for Beta-2AR agonists via FAP method	ADRB2_activators	ADRB2	Beta-2 adrenergic receptor	hemorrhage	EPINEPHRINE	targetBased	2	Unknown status	01/04/2017	https://clinicaltrials.gov/study/NCT03112135	0.2	GoF	protect
HTS for Beta-2AR agonists via FAP method	ADRB2_activators	ADRB2	Beta-2 adrenergic receptor	hemorrhage	EPINEPHRINE	targetBased	3	Completed	01/11/2012	https://clinicaltrials.gov/study/NCT01708642	0.7	GoF	protect
HTS for Beta-2AR agonists via FAP method	ADRB2_activators	ADRB2	Beta-2 adrenergic receptor	hemorrhage	EPINEPHRINE	targetBased	3	Not yet recruiting	01/04/2024	https://clinicaltrials.gov/study/NCT06264596	0.7	GoF	protect
HTS for Beta-2AR agonists via FAP method	ADRB2_activators	ADRB2	Beta-2 adrenergic receptor	hemorrhage	EPINEPHRINE	targetBased	4	Completed	12/05/2017	https://clinicaltrials.gov/study/NCT05867342	1	GoF	protect
HTS for Beta-2AR agonists via FAP method	ADRB2_activators	ADRB2	Beta-2 adrenergic receptor	hemorrhage	EPINEPHRINE	targetBased	2	Completed	01/07/2017	https://clinicaltrials.gov/study/NCT03126968	0.2	GoF	protect
HTS for Beta-2AR agonists via FAP method	ADRB2_activators	ADRB2	Beta-2 adrenergic receptor	hemorrhage	EPINEPHRINE	targetBased	4			https://www.whocc.no/atc_ddd_index/?code=B02BC09	1	GoF	protect
HTS for Beta-2AR agonists via FAP method	ADRB2_activators	ADRB2	Beta-2 adrenergic receptor	hemorrhage	EPINEPHRINE	targetBased	4	Unknown status	01/12/2013	https://clinicaltrials.gov/study/NCT02238288	1	GoF	protect
HTS of Estrogen Receptor- alpha Coactivator Binding inhibitors	ESR1_inhibitors	ESR1	Estrogen receptor, Estrogen receptor	hemorrhage	ETHINYL ESTRADIOL	targetBased	2	Completed	01/10/2006	https://clinicaltrials.gov/study/NCT00394771	0.2	GoF	protect
HTS of Estrogen Receptor- alpha Coactivator Binding Potentiators	ESR1_modulators	ESR1	Estrogen receptor, Estrogen receptor	hemorrhage	ETHINYL ESTRADIOL	targetBased	2	Completed	01/10/2006	https://clinicaltrials.gov/study/NCT00394771	0.2	GoF	protect
HTS of Estrogen Receptor- alpha Coactivator Binding inhibitors	ESR1_inhibitors	ESR1	Estrogen receptor, Estrogen receptor	thrombophilia	ETHINYL ESTRADIOL	targetBased	4	Terminated	01/03/2016	https://clinicaltrials.gov/study/NCT03531437	1	GoF	protect	problem with recruiting participants
HTS of Estrogen Receptor- alpha Coactivator Binding Potentiators	ESR1_modulators	ESR1	Estrogen receptor, Estrogen receptor	thrombophilia	ETHINYL ESTRADIOL	targetBased	4	Terminated	01/03/2016	https://clinicaltrials.gov/study/NCT03531437	1	GoF	protect	problem with recruiting participants
HTS for Beta-2AR agonists via FAP method	ADRB2_activators	ADRB2	Beta-2 adrenergic receptor	hemorrhage	CARVEDILOL	targetBased	4	Terminated	08/07/2011	https://clinicaltrials.gov/study/NCT01383044	1	LoF	protect	slow enrollment
HTS for Beta-2AR agonists via FAP method	ADRB2_activators	ADRB2	Beta-2 adrenergic receptor	hemorrhage	CARVEDILOL	targetBased	4	Completed	01/03/2005	https://clinicaltrials.gov/study/NCT01103154	1	LoF	protect
uHTS identification of small molecule modulators of NR3A	GRIN3A	GRIN3A		Strabismus	KETAMINE	targetBased	2	Completed	01/03/2004	https://clinicaltrials.gov/study/NCT00478907	0.2	LoF	protect
uHTS identification of small molecule modulators of NR3A	GRIN3A	GRIN3A		hemorrhage	KETAMINE	targetBased	4	Completed	01/06/2018	https://clinicaltrials.gov/study/NCT03621085	1	LoF	protect
HTS of Estrogen Receptor- alpha Coactivator Binding inhibitors	ESR1_inhibitors	ESR1	Estrogen receptor, Estrogen receptor	hemorrhage	TAMOXIFEN CITRATE	targetBased	4	Withdrawn	01/05/2022	https://clinicaltrials.gov/study/NCT04933240	1		protect	Anticipated funding was not received
HTS of Estrogen Receptor- alpha Coactivator Binding Potentiators	ESR1_modulators	ESR1	Estrogen receptor, Estrogen receptor	hemorrhage	TAMOXIFEN CITRATE	targetBased	4	Withdrawn	01/05/2022	https://clinicaltrials.gov/study/NCT04933240	1		protect	Anticipated funding was not received
HTS of Estrogen Receptor- alpha Coactivator Binding inhibitors	ESR1_inhibitors	ESR1	Estrogen receptor, Estrogen receptor	hemorrhage	TAMOXIFEN CITRATE	targetBased	4	Completed	20/01/2017	https://clinicaltrials.gov/study/NCT02903121	1		protect
HTS of Estrogen Receptor- alpha Coactivator Binding Potentiators	ESR1_modulators	ESR1	Estrogen receptor, Estrogen receptor	hemorrhage	TAMOXIFEN CITRATE	targetBased	4	Completed	20/01/2017	https://clinicaltrials.gov/study/NCT02903121	1		protect
Inhibitors of the vitamin D receptor (VDR): qHTS	VDR	VDR	Vitamin D3 receptor	Proteinuria	CALCITRIOL	targetBased	4	Unknown status	01/01/2012	https://clinicaltrials.gov/study/NCT01512862	1	GoF	protect
ROC1-CUL1 CTD Inhibitor di-Ub FRET Primary HTS Screen	RBX1	RBX1	E3 ubiquitin-protein ligase RBX1	anemia	LENALIDOMIDE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5fa97bf5-28a2-48f1-8955-f56012d296be	1	LoF	protect
ROC1-CUL1 CTD Inhibitor di-Ub FRET Primary HTS Screen	RBX1	RBX1	E3 ubiquitin-protein ligase RBX1	anemia (phenotype)	LENALIDOMIDE	targetBased	3	Completed	26/01/2010	https://clinicaltrials.gov/study/NCT01029262	0.7	LoF	protect
ROC1-CUL1 CTD Inhibitor di-Ub FRET Primary HTS Screen	RBX1	RBX1	E3 ubiquitin-protein ligase RBX1	Abnormality of blood and blood-forming tissues	LENALIDOMIDE	targetBased	2	Terminated	24/11/2014	https://clinicaltrials.gov/study/NCT01924169	0.2	LoF	protect	Slow Accrual
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	hemorrhage	DABIGATRAN	targetBased	2	Withdrawn	09/03/2022	https://clinicaltrials.gov/study/NCT04002011	0.2	LoF	protect	Submission process abandoned. No patient enrolled.
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	Thromboembolism	DABIGATRAN	targetBased	3	Completed	01/11/2004	https://clinicaltrials.gov/study/NCT00152971	0.7	LoF	protect
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	Thromboembolism	DABIGATRAN	targetBased	3	Completed	01/05/2006	https://clinicaltrials.gov/study/NCT00329238	0.7	LoF	protect
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of the interaction of the Ras and Rab interactor 1 protein (Rin1) and the c-abl oncogene 1, non-receptor tyrosine kinase (Abl)	ABL1_interaction	ABL1	Tyrosine-protein kinase ABL1	Eosinophilia	IMATINIB	targetBased	2	Terminated	12/06/2003	https://clinicaltrials.gov/study/NCT00230334	0.2	LoF	protect	terminated by PI due to insufficient accrual
Inhibitors of the vitamin D receptor (VDR): qHTS	VDR	VDR	Vitamin D3 receptor	Iron deficiency anemia	CHOLECALCIFEROL	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=bf9624d8-b2ef-45a4-9ad6-a3b8701e76b7	1	GoF	protect
Inhibitors of the vitamin D receptor (VDR): qHTS	VDR	VDR	Vitamin D3 receptor	anemia (phenotype)	CHOLECALCIFEROL	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=3c2df670-f894-48e5-b08a-6ad5d293429b	1	GoF	protect
Inhibitors of the vitamin D receptor (VDR): qHTS	VDR	VDR	Vitamin D3 receptor	anemia (phenotype)	CHOLECALCIFEROL	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5e273c62-e582-4a40-90aa-c7c723cbcdf1	1	GoF	protect
Inhibitors of the vitamin D receptor (VDR): qHTS	VDR	VDR	Vitamin D3 receptor	anemia (phenotype)	CHOLECALCIFEROL	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=d68362a4-05ca-4062-8863-62c5a2d8177a	1	GoF	protect
uHTS identification of small molecule modulators of NR3A	GRIN3A	GRIN3A		anemia	FELBAMATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2f522701-397a-11de-8a39-0800200c9a66	1	LoF	protect
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	Recurrent thrombophlebitis	ARGATROBAN	targetBased	4			https://www.whocc.no/atc_ddd_index/?code=B01AE03	1	LoF	protect
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	Thrombocytopenia	ARGATROBAN	targetBased	3	Terminated	16/05/2019	https://clinicaltrials.gov/study/NCT03809481	0.7	LoF	protect	Prolonged delay as a result of impact of Covid19 pandemic
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	Thrombocytopenia	ARGATROBAN	targetBased	3	Completed	01/06/2005	https://clinicaltrials.gov/study/NCT00198588	0.7	LoF	protect
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	Thrombocytopenia	ARGATROBAN	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=cea3f6aa-cd1c-4152-98bb-bbb7b977497a	1	LoF	protect
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	Thrombocytopenia	ARGATROBAN	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=641c4c2b-87a3-44ca-a126-f83a4d58e988	1	LoF	protect
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	Thrombocytopenia	ARGATROBAN	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=35db0a86-76af-4f5e-a5c6-0a664f53f6da	1	LoF	protect
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	Thrombocytopenia	ARGATROBAN	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0cdf3f67-5bf3-4d58-b330-03febdc652bf	1	LoF	protect
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	Thrombocytopenia	ARGATROBAN	targetBased	4	Terminated	01/09/2008	https://clinicaltrials.gov/study/NCT00787332	1	LoF	protect	Low enrollment
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	Thrombocytopenia	ARGATROBAN	targetBased	4	Completed	01/09/2003	https://clinicaltrials.gov/study/NCT00039858	1	LoF	protect
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	Thrombocytopenia	ARGATROBAN	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b0dedf95-8395-46bf-b94a-dcf2dd085942	1	LoF	protect
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	Thrombocytopenia	ARGATROBAN	targetBased	2	Completed	01/04/2009	https://clinicaltrials.gov/study/NCT00861692	0.2	LoF	protect
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	Thrombocytopenia	ARGATROBAN	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=34fb6cda-e236-4803-b599-a9b048d33513	1	LoF	protect
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	Thrombocytopenia	ARGATROBAN	targetBased	4	Withdrawn	01/01/2008	https://clinicaltrials.gov/study/NCT00603824	1	LoF	protect	PI relocated
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	Thrombocytopenia	ARGATROBAN	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=9c9616c0-a299-4fd5-c8ae-79e6db453595	1	LoF	protect
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	Thrombocytopenia	ARGATROBAN	targetBased	4	Terminated	01/01/2009	https://clinicaltrials.gov/study/NCT00798525	1	LoF	protect	Supply of Lepirudin ended on 01. April 2012, thus trial terminated on 31. March 2012
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	Thrombocytopenia	ARGATROBAN	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ad7a4516-210f-4ad9-af75-dc11b1376d50	1	LoF	protect
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	hemorrhagic disease	ARGATROBAN	targetBased	2	Recruiting	01/12/2021	https://clinicaltrials.gov/study/NCT05226442	0.2	LoF	protect
HTS for Beta-2AR agonists via FAP method	ADRB2_activators	ADRB2	Beta-2 adrenergic receptor	hemorrhage	EPHEDRINE	targetBased	2	Completed	01/01/2016	https://clinicaltrials.gov/study/NCT02622126	0.2	GoF	protect
HTS for Beta-2AR agonists via FAP method	ADRB2_activators	ADRB2	Beta-2 adrenergic receptor	blood coagulation disease	EPHEDRINE	targetBased	2	Completed	01/01/2016	https://clinicaltrials.gov/study/NCT02622126	0.2	GoF	protect
Counterscreen for Oxytocin Receptor (OXTR) agonists: Fluorescence-based primary cell-based high throughput assay to identify agonists of the vasopressin 1 receptor (V1R)	AVPR1A_agonists	AVPR1A	Vasopressin V1a receptor	hemorrhage	VASOPRESSIN	targetBased	4	Completed	01/01/2004	https://clinicaltrials.gov/study/NCT00799292	1	GoF	protect
Counterscreen for Oxytocin Receptor (OXTR) agonists: Fluorescence-based primary cell-based high throughput assay to identify agonists of the vasopressin 1 receptor (V1R)	AVPR1A_agonists	AVPR1A	Vasopressin V1a receptor	hemorrhage	VASOPRESSIN	targetBased	4	Completed	01/02/2005	https://clinicaltrials.gov/study/NCT01700478	1	GoF	protect
Counterscreen for Oxytocin Receptor (OXTR) agonists: Fluorescence-based primary cell-based high throughput assay to identify agonists of the vasopressin 1 receptor (V1R)	AVPR1A_agonists	AVPR1A	Vasopressin V1a receptor	Abnormality of blood and blood-forming tissues	DESMOPRESSIN	targetBased	4	Unknown status	01/02/2015	https://clinicaltrials.gov/study/NCT03343418	1	GoF	protect
Counterscreen for Oxytocin Receptor (OXTR) agonists: Fluorescence-based primary cell-based high throughput assay to identify agonists of the vasopressin 1 receptor (V1R)	AVPR1A_agonists	AVPR1A	Vasopressin V1a receptor	hemorrhage	DESMOPRESSIN	targetBased	4	Completed	01/06/2006	https://clinicaltrials.gov/study/NCT00337766	1	GoF	protect
Counterscreen for Oxytocin Receptor (OXTR) agonists: Fluorescence-based primary cell-based high throughput assay to identify agonists of the vasopressin 1 receptor (V1R)	AVPR1A_agonists	AVPR1A	Vasopressin V1a receptor	hemorrhage	DESMOPRESSIN	targetBased	2	Completed	01/07/2022	https://clinicaltrials.gov/study/NCT05430048	0.2	GoF	protect
Counterscreen for Oxytocin Receptor (OXTR) agonists: Fluorescence-based primary cell-based high throughput assay to identify agonists of the vasopressin 1 receptor (V1R)	AVPR1A_agonists	AVPR1A	Vasopressin V1a receptor	hemorrhage	DESMOPRESSIN	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c7c7ee28-c820-44a2-a441-234c2e43cd18	1	GoF	protect
Counterscreen for Oxytocin Receptor (OXTR) agonists: Fluorescence-based primary cell-based high throughput assay to identify agonists of the vasopressin 1 receptor (V1R)	AVPR1A_agonists	AVPR1A	Vasopressin V1a receptor	hemorrhage	DESMOPRESSIN	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=9fd48eec-aa24-4888-b99f-d409ada958a7	1	GoF	protect
Counterscreen for Oxytocin Receptor (OXTR) agonists: Fluorescence-based primary cell-based high throughput assay to identify agonists of the vasopressin 1 receptor (V1R)	AVPR1A_agonists	AVPR1A	Vasopressin V1a receptor	hemorrhage	DESMOPRESSIN	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5fe83452-1670-487d-feb4-27d4bd75a147	1	GoF	protect
Counterscreen for Oxytocin Receptor (OXTR) agonists: Fluorescence-based primary cell-based high throughput assay to identify agonists of the vasopressin 1 receptor (V1R)	AVPR1A_agonists	AVPR1A	Vasopressin V1a receptor	hemorrhage	DESMOPRESSIN	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=30d4c387-b99c-49f8-a8bd-de23fdafb739	1	GoF	protect
Counterscreen for Oxytocin Receptor (OXTR) agonists: Fluorescence-based primary cell-based high throughput assay to identify agonists of the vasopressin 1 receptor (V1R)	AVPR1A_agonists	AVPR1A	Vasopressin V1a receptor	hemorrhage	DESMOPRESSIN	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=651f6fee-a2c7-431b-8d5d-58b156c72244	1	GoF	protect
Counterscreen for Oxytocin Receptor (OXTR) agonists: Fluorescence-based primary cell-based high throughput assay to identify agonists of the vasopressin 1 receptor (V1R)	AVPR1A_agonists	AVPR1A	Vasopressin V1a receptor	hemorrhage	DESMOPRESSIN	targetBased	4	Terminated	01/03/2009	https://clinicaltrials.gov/study/NCT00885924	1	GoF	protect	to include required number of patients took too much time
Counterscreen for Oxytocin Receptor (OXTR) agonists: Fluorescence-based primary cell-based high throughput assay to identify agonists of the vasopressin 1 receptor (V1R)	AVPR1A_agonists	AVPR1A	Vasopressin V1a receptor	hemorrhage	DESMOPRESSIN	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2dc2cec8-6953-4a33-9356-11534fba1fb8	1	GoF	protect
Counterscreen for Oxytocin Receptor (OXTR) agonists: Fluorescence-based primary cell-based high throughput assay to identify agonists of the vasopressin 1 receptor (V1R)	AVPR1A_agonists	AVPR1A	Vasopressin V1a receptor	von Willebrand disease (hereditary or acquired)	DESMOPRESSIN	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=651f6fee-a2c7-431b-8d5d-58b156c72244	1	GoF	protect
Counterscreen for Oxytocin Receptor (OXTR) agonists: Fluorescence-based primary cell-based high throughput assay to identify agonists of the vasopressin 1 receptor (V1R)	AVPR1A_agonists	AVPR1A	Vasopressin V1a receptor	hemophilia A	DESMOPRESSIN	targetBased	4	Completed	31/07/2018	https://clinicaltrials.gov/study/NCT03379974	1	GoF	protect
Counterscreen for Oxytocin Receptor (OXTR) agonists: Fluorescence-based primary cell-based high throughput assay to identify agonists of the vasopressin 1 receptor (V1R)	AVPR1A_agonists	AVPR1A	Vasopressin V1a receptor	hemophilia A	DESMOPRESSIN	targetBased	4	Unknown status	04/07/2017	https://clinicaltrials.gov/study/NCT03136003	1	GoF	protect
Fluorescence-based primary cell-based high throughput screening assay to identify agonists of the Oxytocin Receptor (OXTR).	OXTR	OXTR	Oxytocin receptor	hemorrhage	OXYTOCIN	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c7fd585a-99b7-4309-b003-a6cbef05372c	1	GoF	protect
Fluorescence-based primary cell-based high throughput screening assay to identify agonists of the Oxytocin Receptor (OXTR).	OXTR	OXTR	Oxytocin receptor	hemorrhage	OXYTOCIN	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=6d7d1280-f286-4f39-89f3-2b96571810e6	1	GoF	protect
Fluorescence-based primary cell-based high throughput screening assay to identify agonists of the Oxytocin Receptor (OXTR).	OXTR	OXTR	Oxytocin receptor	hemorrhage	OXYTOCIN	targetBased	3	Not yet recruiting	01/06/2016	https://clinicaltrials.gov/study/NCT02453568	0.7	GoF	protect
Fluorescence-based primary cell-based high throughput screening assay to identify agonists of the Oxytocin Receptor (OXTR).	OXTR	OXTR	Oxytocin receptor	hemorrhage	OXYTOCIN	targetBased	2	Not yet recruiting	20/11/2023	https://clinicaltrials.gov/study/NCT06141447	0.2	GoF	protect
Fluorescence-based primary cell-based high throughput screening assay to identify agonists of the Oxytocin Receptor (OXTR).	OXTR	OXTR	Oxytocin receptor	hemorrhage	OXYTOCIN	targetBased	4	Completed	01/05/2014	https://clinicaltrials.gov/study/NCT02101567	1	GoF	protect
Fluorescence-based primary cell-based high throughput screening assay to identify agonists of the Oxytocin Receptor (OXTR).	OXTR	OXTR	Oxytocin receptor	hemorrhage	OXYTOCIN	targetBased	4	Not yet recruiting	01/11/2020	https://clinicaltrials.gov/study/NCT04595812	1	GoF	protect
Fluorescence-based primary cell-based high throughput screening assay to identify agonists of the Oxytocin Receptor (OXTR).	OXTR	OXTR	Oxytocin receptor	hemorrhage	OXYTOCIN	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=18fe8365-86e3-414e-84dc-c98e097a2f36	1	GoF	protect
Fluorescence-based primary cell-based high throughput screening assay to identify agonists of the Oxytocin Receptor (OXTR).	OXTR	OXTR	Oxytocin receptor	hemorrhage	OXYTOCIN	targetBased	2	Not yet recruiting	01/07/2024	https://clinicaltrials.gov/study/NCT05488457	0.2	GoF	protect
uHTS identification of DNMT1 inhibitors in a Fluorescent Molecular Beacon assay	DNMT1	DNMT1	DNA methyltransferase-1	anemia	AZACITIDINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=3495a71a-cc04-4776-851f-f185956f32af	1	LoF	protect
uHTS identification of DNMT1 inhibitors in a Fluorescent Molecular Beacon assay	DNMT1	DNMT1	DNA methyltransferase-1	Thrombocytopenia	AZACITIDINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=3495a71a-cc04-4776-851f-f185956f32af	1	LoF	protect
uHTS identification of DNMT1 inhibitors in a Fluorescent Molecular Beacon assay	DNMT1	DNMT1	DNA methyltransferase-1	Thrombocytopenia	AZACITIDINE	targetBased	2	Not yet recruiting	01/12/2021	https://clinicaltrials.gov/study/NCT05126004	0.2	LoF	protect
uHTS identification of DNMT1 inhibitors in a Fluorescent Molecular Beacon assay	DNMT1	DNMT1	DNA methyltransferase-1	Thrombocytopenia	AZACITIDINE	targetBased	3	Terminated	10/06/2014	https://clinicaltrials.gov/study/NCT02158936	0.7	LoF	protect
HTS for Inhibition of CaV1.3 ICDI/IQ interaction using a live-cell FRET assay Measured in Cell-Based System Using Plate Reader - 7081-01_Inhibitor_SinglePoint_HTS_Activity	CACNA1D_inhibitors	CACNA1D	Voltage-dependent N-type calcium channel subunit alpha-1B	Proteinuria	AMLODIPINE	targetBased	3	Completed	01/06/2007	https://clinicaltrials.gov/study/NCT00568178	0.7	LoF	protect
HTS for Inhibition of CaV1.3 ICDI/IQ interaction using a live-cell FRET assay Measured in Cell-Based System Using Plate Reader - 7081-01_Inhibitor_SinglePoint_HTS_Activity	CACNA1D_inhibitors	CACNA1D	Voltage-dependent N-type calcium channel subunit alpha-1B	albuminuria	AMLODIPINE	targetBased	4	Completed	01/04/2003	https://clinicaltrials.gov/study/NCT00136773	1	LoF	protect
HTS for Inhibition of CaV1.3 ICDI/IQ interaction using a live-cell FRET assay Measured in Cell-Based System Using Plate Reader - 7081-01_Inhibitor_SinglePoint_HTS_Activity	CACNA1D_inhibitors	CACNA1D	Voltage-dependent N-type calcium channel subunit alpha-1B	Thalassemia	AMLODIPINE	targetBased	2	Completed	01/02/2014	https://clinicaltrials.gov/study/NCT02065492	0.2	LoF	protect
HTS for Inhibition of CaV1.3 ICDI/IQ interaction using a live-cell FRET assay Measured in Cell-Based System Using Plate Reader - 7081-01_Inhibitor_SinglePoint_HTS_Activity	CACNA1D_inhibitors	CACNA1D	Voltage-dependent N-type calcium channel subunit alpha-1B	Proteinuria	NIFEDIPINE	targetBased	2	Unknown status	01/05/2007	https://clinicaltrials.gov/study/NCT00817037	0.2	LoF	protect
Fluorescence-based cell-based primary high throughput screening assay to identify inhibitors of TLR9-MyD88 binding.	TLR9	TLR9	Toll-like receptor 9	Thrombocytopenia	HYDROXYCHLOROQUINE	targetBased	3	Terminated	01/07/2015	https://clinicaltrials.gov/study/NCT02444728	0.7	LoF	protect	Because of insufficient enrollement
Inhibitors of the vitamin D receptor (VDR): qHTS	VDR	VDR	Vitamin D3 receptor	blood coagulation disease	ERGOCALCIFEROL	targetBased	2	Withdrawn	01/05/2020	https://clinicaltrials.gov/study/NCT04363840	0.2	GoF	protect	lack of funding
Fluorescence-based cell-based primary high throughput screening assay to identify agonists of the human cholinergic receptor, muscarinic 1 (CHRM1)	CHRM1_agonists	CHRM1	Muscarinic acetylcholine receptor M1	Strabismus	ATROPINE	targetBased	3	Completed	01/05/1999	https://clinicaltrials.gov/study/NCT00001864	0.7	LoF	protect
Discovery of Novel Allosteric Modulators of the M1 Muscarinic Receptor: Agonist Primary Screen	CHRM1_allosteric_activators	CHRM1	Muscarinic acetylcholine receptor M1	Strabismus	ATROPINE	targetBased	3	Completed	01/05/1999	https://clinicaltrials.gov/study/NCT00001864	0.7	LoF	protect
Fluorescence-based cell-based primary high throughput screening assay to identify positive allosteric modulators (PAMs) of the human M1 muscarinic receptor (CHRM1).	CHRM1_PAMs	CHRM1	Muscarinic acetylcholine receptor M1	Strabismus	ATROPINE	targetBased	3	Completed	01/05/1999	https://clinicaltrials.gov/study/NCT00001864	0.7	LoF	protect
Discovery of novel allosteric modulators of the M1 muscarinic receptor: Antagonist Primary Screen	CHRM1_allosteric_antagonists	CHRM1	Muscarinic acetylcholine receptor M1	Strabismus	ATROPINE	targetBased	3	Completed	01/05/1999	https://clinicaltrials.gov/study/NCT00001864	0.7	LoF	protect
Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the human M1 muscarinic receptor (CHRM1)	CHRM1_antgonists	CHRM1	Muscarinic acetylcholine receptor M1	Strabismus	ATROPINE	targetBased	3	Completed	01/05/1999	https://clinicaltrials.gov/study/NCT00001864	0.7	LoF	protect
Fluorescence-based cell-based primary high throughput screening assay to identify agonists of the human cholinergic receptor, muscarinic 1 (CHRM1)	CHRM1_agonists	CHRM1	Muscarinic acetylcholine receptor M1	blood coagulation	ATROPINE	targetBased	3	Completed	12/10/2011	https://clinicaltrials.gov/study/NCT01422304	0.7	LoF	protect
Discovery of Novel Allosteric Modulators of the M1 Muscarinic Receptor: Agonist Primary Screen	CHRM1_allosteric_activators	CHRM1	Muscarinic acetylcholine receptor M1	blood coagulation	ATROPINE	targetBased	3	Completed	12/10/2011	https://clinicaltrials.gov/study/NCT01422304	0.7	LoF	protect
Fluorescence-based cell-based primary high throughput screening assay to identify positive allosteric modulators (PAMs) of the human M1 muscarinic receptor (CHRM1).	CHRM1_PAMs	CHRM1	Muscarinic acetylcholine receptor M1	blood coagulation	ATROPINE	targetBased	3	Completed	12/10/2011	https://clinicaltrials.gov/study/NCT01422304	0.7	LoF	protect
Discovery of novel allosteric modulators of the M1 muscarinic receptor: Antagonist Primary Screen	CHRM1_allosteric_antagonists	CHRM1	Muscarinic acetylcholine receptor M1	blood coagulation	ATROPINE	targetBased	3	Completed	12/10/2011	https://clinicaltrials.gov/study/NCT01422304	0.7	LoF	protect
Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the human M1 muscarinic receptor (CHRM1)	CHRM1_antgonists	CHRM1	Muscarinic acetylcholine receptor M1	blood coagulation	ATROPINE	targetBased	3	Completed	12/10/2011	https://clinicaltrials.gov/study/NCT01422304	0.7	LoF	protect
Fluorescence-based cell-based primary high throughput screening assay to identify agonists of the human cholinergic receptor, muscarinic 1 (CHRM1)	CHRM1_agonists	CHRM1	Muscarinic acetylcholine receptor M1	hemorrhage	ATROPINE	targetBased	2	Completed	01/01/2016	https://clinicaltrials.gov/study/NCT02622126	0.2	LoF	protect
Discovery of Novel Allosteric Modulators of the M1 Muscarinic Receptor: Agonist Primary Screen	CHRM1_allosteric_activators	CHRM1	Muscarinic acetylcholine receptor M1	hemorrhage	ATROPINE	targetBased	2	Completed	01/01/2016	https://clinicaltrials.gov/study/NCT02622126	0.2	LoF	protect
Fluorescence-based cell-based primary high throughput screening assay to identify positive allosteric modulators (PAMs) of the human M1 muscarinic receptor (CHRM1).	CHRM1_PAMs	CHRM1	Muscarinic acetylcholine receptor M1	hemorrhage	ATROPINE	targetBased	2	Completed	01/01/2016	https://clinicaltrials.gov/study/NCT02622126	0.2	LoF	protect
Discovery of novel allosteric modulators of the M1 muscarinic receptor: Antagonist Primary Screen	CHRM1_allosteric_antagonists	CHRM1	Muscarinic acetylcholine receptor M1	hemorrhage	ATROPINE	targetBased	2	Completed	01/01/2016	https://clinicaltrials.gov/study/NCT02622126	0.2	LoF	protect
Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the human M1 muscarinic receptor (CHRM1)	CHRM1_antgonists	CHRM1	Muscarinic acetylcholine receptor M1	hemorrhage	ATROPINE	targetBased	2	Completed	01/01/2016	https://clinicaltrials.gov/study/NCT02622126	0.2	LoF	protect
Fluorescence-based cell-based primary high throughput screening assay to identify agonists of the human cholinergic receptor, muscarinic 1 (CHRM1)	CHRM1_agonists	CHRM1	Muscarinic acetylcholine receptor M1	blood coagulation disease	ATROPINE	targetBased	2	Completed	01/01/2016	https://clinicaltrials.gov/study/NCT02622126	0.2	LoF	protect
Discovery of Novel Allosteric Modulators of the M1 Muscarinic Receptor: Agonist Primary Screen	CHRM1_allosteric_activators	CHRM1	Muscarinic acetylcholine receptor M1	blood coagulation disease	ATROPINE	targetBased	2	Completed	01/01/2016	https://clinicaltrials.gov/study/NCT02622126	0.2	LoF	protect
Fluorescence-based cell-based primary high throughput screening assay to identify positive allosteric modulators (PAMs) of the human M1 muscarinic receptor (CHRM1).	CHRM1_PAMs	CHRM1	Muscarinic acetylcholine receptor M1	blood coagulation disease	ATROPINE	targetBased	2	Completed	01/01/2016	https://clinicaltrials.gov/study/NCT02622126	0.2	LoF	protect
Discovery of novel allosteric modulators of the M1 muscarinic receptor: Antagonist Primary Screen	CHRM1_allosteric_antagonists	CHRM1	Muscarinic acetylcholine receptor M1	blood coagulation disease	ATROPINE	targetBased	2	Completed	01/01/2016	https://clinicaltrials.gov/study/NCT02622126	0.2	LoF	protect
Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the human M1 muscarinic receptor (CHRM1)	CHRM1_antgonists	CHRM1	Muscarinic acetylcholine receptor M1	blood coagulation disease	ATROPINE	targetBased	2	Completed	01/01/2016	https://clinicaltrials.gov/study/NCT02622126	0.2	LoF	protect
HTS for Beta-2AR agonists via FAP method	ADRB2_activators	ADRB2	Beta-2 adrenergic receptor	hemorrhage	nadolol	targetBased	4	Completed	01/03/2005	https://clinicaltrials.gov/study/NCT01103154	1	LoF	protect
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	Thromboembolism	XIMELAGATRAN	targetBased	3	Terminated	01/09/2005	https://clinicaltrials.gov/study/NCT00206089	0.35	LoF	protect	Melagatran/ximelagatran was withdrawn from the market and clinical development in February 2006 in the interest of patient safety.
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	Recurrent thrombophlebitis	XIMELAGATRAN	targetBased	4			https://www.whocc.no/atc_ddd_index/?code=B01AE05	1	LoF	protect
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of the interaction of the Ras and Rab interactor 1 protein (Rin1) and the c-abl oncogene 1, non-receptor tyrosine kinase (Abl)	ABL1_interaction	ABL1	Tyrosine-protein kinase ABL1	Eosinophilia	IMATINIB MESYLATE	targetBased	2	Terminated	12/06/2003	https://clinicaltrials.gov/study/NCT00230334	0.2	LoF	protect	terminated by PI due to insufficient accrual
uHTS identification of small molecule modulators of NR3A	GRIN3A	GRIN3A		hemorrhage	KETAMINE HYDROCHLORIDE	targetBased	4	Completed	01/06/2018	https://clinicaltrials.gov/study/NCT03621085	1	LoF	protect
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	deep vein thrombosis	DABIGATRAN ETEXILATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ba74e3cd-b06f-4145-b284-5fd6b84ff3c9	1	LoF	protect
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	Venous thrombosis	DABIGATRAN ETEXILATE	targetBased	3	Unknown status	01/08/2017	https://clinicaltrials.gov/study/NCT03217448	0.7	LoF	protect
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	Venous thrombosis	DABIGATRAN ETEXILATE	targetBased	2	Terminated	01/07/2014	https://clinicaltrials.gov/study/NCT02256683	0.2	LoF	protect	Recruiting problems
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	Venous thrombosis	DABIGATRAN ETEXILATE	targetBased	2	Completed	01/10/2005	https://clinicaltrials.gov/study/NCT00246025	0.2	LoF	protect
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	Thromboembolism	DABIGATRAN ETEXILATE	targetBased	3	Completed	01/11/2004	https://clinicaltrials.gov/study/NCT00168818	0.7	LoF	protect
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	Thromboembolism	DABIGATRAN ETEXILATE	targetBased	3	Completed	13/12/2016	https://clinicaltrials.gov/study/NCT02913326	0.7	LoF	protect
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	Thromboembolism	DABIGATRAN ETEXILATE	targetBased	3	Completed	01/04/2008	https://clinicaltrials.gov/study/NCT00680186	0.7	LoF	protect
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	Thromboembolism	DABIGATRAN ETEXILATE	targetBased	3	Completed	01/11/2004	https://clinicaltrials.gov/study/NCT00168805	0.7	LoF	protect
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	Thromboembolism	DABIGATRAN ETEXILATE	targetBased	3	Completed	01/02/2006	https://clinicaltrials.gov/study/NCT00291330	0.7	LoF	protect
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	Thromboembolism	DABIGATRAN ETEXILATE	targetBased	2	Terminated	01/12/2011	https://clinicaltrials.gov/study/NCT01505881	0.2	LoF	protect
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	Recurrent thrombophlebitis	DABIGATRAN ETEXILATE	targetBased	4			https://www.whocc.no/atc_ddd_index/?code=B01AE07	1	LoF	protect
HTS for Inhibition of CaV1.3 ICDI/IQ interaction using a live-cell FRET assay Measured in Cell-Based System Using Plate Reader - 7081-01_Inhibitor_SinglePoint_HTS_Activity	CACNA1D_inhibitors	CACNA1D	Voltage-dependent N-type calcium channel subunit alpha-1B	Proteinuria	AMLODIPINE BESYLATE	targetBased	3	Completed	01/06/2007	https://clinicaltrials.gov/study/NCT00568178	0.7	LoF	protect
Counterscreen for Oxytocin Receptor (OXTR) agonists: Fluorescence-based primary cell-based high throughput assay to identify agonists of the vasopressin 1 receptor (V1R)	AVPR1A_agonists	AVPR1A	Vasopressin V1a receptor	hemorrhage	DESMOPRESSIN ACETATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=651f6fee-a2c7-431b-8d5d-58b156c72244	1	GoF	protect
Counterscreen for Oxytocin Receptor (OXTR) agonists: Fluorescence-based primary cell-based high throughput assay to identify agonists of the vasopressin 1 receptor (V1R)	AVPR1A_agonists	AVPR1A	Vasopressin V1a receptor	hemorrhage	DESMOPRESSIN ACETATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5fe83452-1670-487d-feb4-27d4bd75a147	1	GoF	protect
Counterscreen for Oxytocin Receptor (OXTR) agonists: Fluorescence-based primary cell-based high throughput assay to identify agonists of the vasopressin 1 receptor (V1R)	AVPR1A_agonists	AVPR1A	Vasopressin V1a receptor	hemorrhage	DESMOPRESSIN ACETATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c7c7ee28-c820-44a2-a441-234c2e43cd18	1	GoF	protect
Counterscreen for Oxytocin Receptor (OXTR) agonists: Fluorescence-based primary cell-based high throughput assay to identify agonists of the vasopressin 1 receptor (V1R)	AVPR1A_agonists	AVPR1A	Vasopressin V1a receptor	hemorrhage	DESMOPRESSIN ACETATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=30d4c387-b99c-49f8-a8bd-de23fdafb739	1	GoF	protect
Counterscreen for Oxytocin Receptor (OXTR) agonists: Fluorescence-based primary cell-based high throughput assay to identify agonists of the vasopressin 1 receptor (V1R)	AVPR1A_agonists	AVPR1A	Vasopressin V1a receptor	hemorrhage	DESMOPRESSIN ACETATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2dc2cec8-6953-4a33-9356-11534fba1fb8	1	GoF	protect
Counterscreen for Oxytocin Receptor (OXTR) agonists: Fluorescence-based primary cell-based high throughput assay to identify agonists of the vasopressin 1 receptor (V1R)	AVPR1A_agonists	AVPR1A	Vasopressin V1a receptor	hemorrhage	DESMOPRESSIN ACETATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=9fd48eec-aa24-4888-b99f-d409ada958a7	1	GoF	protect
Counterscreen for Oxytocin Receptor (OXTR) agonists: Fluorescence-based primary cell-based high throughput assay to identify agonists of the vasopressin 1 receptor (V1R)	AVPR1A_agonists	AVPR1A	Vasopressin V1a receptor	hemorrhage	DESMOPRESSIN ACETATE	targetBased	4	Completed	01/06/2006	https://clinicaltrials.gov/study/NCT00337766	1	GoF	protect
Counterscreen for Oxytocin Receptor (OXTR) agonists: Fluorescence-based primary cell-based high throughput assay to identify agonists of the vasopressin 1 receptor (V1R)	AVPR1A_agonists	AVPR1A	Vasopressin V1a receptor	von Willebrand disease (hereditary or acquired)	DESMOPRESSIN ACETATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=651f6fee-a2c7-431b-8d5d-58b156c72244	1	GoF	protect
Counterscreen for Oxytocin Receptor (OXTR) agonists: Fluorescence-based primary cell-based high throughput assay to identify agonists of the vasopressin 1 receptor (V1R)	AVPR1A_agonists	AVPR1A	Vasopressin V1a receptor	hemophilia A	DESMOPRESSIN ACETATE	targetBased	4	Completed	31/07/2018	https://clinicaltrials.gov/study/NCT03379974	1	GoF	protect
Counterscreen for Oxytocin Receptor (OXTR) agonists: Fluorescence-based primary cell-based high throughput assay to identify agonists of the vasopressin 1 receptor (V1R)	AVPR1A_agonists	AVPR1A	Vasopressin V1a receptor	hemophilia A	DESMOPRESSIN ACETATE	targetBased	4	Unknown status	04/07/2017	https://clinicaltrials.gov/study/NCT03136003	1	GoF	protect
Inhibitors of the vitamin D receptor (VDR): qHTS	VDR	VDR	Vitamin D3 receptor	albuminuria	PARICALCITOL	targetBased	3	Completed	01/07/2012	https://clinicaltrials.gov/study/NCT01436747	0.7	GoF	protect
Inhibitors of the vitamin D receptor (VDR): qHTS	VDR	VDR	Vitamin D3 receptor	Proteinuria	PARICALCITOL	targetBased	3	Completed	01/01/2013	https://clinicaltrials.gov/study/NCT01694160	0.7	GoF	protect
Inhibitors of the vitamin D receptor (VDR): qHTS	VDR	VDR	Vitamin D3 receptor	anemia (phenotype)	PARICALCITOL	targetBased	4	Recruiting	01/12/2014	https://clinicaltrials.gov/study/NCT02876211	1	GoF	protect
Primary cell-based screen for identification of compounds that inhibit the two-pore domain potassium channel KCNK3	KCNK3	KCNK3	Potassium channel subfamily K member 3	hemorrhage	SEVOFLURANE	targetBased	4	Completed	01/09/2009	https://clinicaltrials.gov/study/NCT01048658	1		protect
Primary cell-based screen for identification of compounds that inhibit the two-pore domain potassium channel KCNK9	KCNK9_blockers	KCNK9	two-pore domain potassium channel	hemorrhage	SEVOFLURANE	targetBased	4	Completed	01/09/2009	https://clinicaltrials.gov/study/NCT01048658	1		protect
Allosteric Agonists of the Human D1 Dopamine Receptor: qHTS	D1_activators	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=53179d26-7dda-4770-a312-37e28f2dc375	1	LoF	protect
Allosteric Modulators of D1 Receptors: Primary Screen	D1	DRD1	Dopamine receptor D1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=53179d26-7dda-4770-a312-37e28f2dc375	1	LoF	protect
Antagonist of Human D 1 Dopamine Receptor: qHTS	D1_inhibitors	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=53179d26-7dda-4770-a312-37e28f2dc375	1	LoF	protect
Allosteric Agonists of the Human D1 Dopamine Receptor: qHTS	D1_activators	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b91d1729-2e8e-4398-9a0d-02763bcfe284	1	LoF	protect
Allosteric Modulators of D1 Receptors: Primary Screen	D1	DRD1	Dopamine receptor D1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b91d1729-2e8e-4398-9a0d-02763bcfe284	1	LoF	protect
Antagonist of Human D 1 Dopamine Receptor: qHTS	D1_inhibitors	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b91d1729-2e8e-4398-9a0d-02763bcfe284	1	LoF	protect
Allosteric Agonists of the Human D1 Dopamine Receptor: qHTS	D1_activators	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=94c9b1cf-ae12-45f3-8fcb-708a922cbc10	1	LoF	protect
Allosteric Modulators of D1 Receptors: Primary Screen	D1	DRD1	Dopamine receptor D1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=94c9b1cf-ae12-45f3-8fcb-708a922cbc10	1	LoF	protect
Antagonist of Human D 1 Dopamine Receptor: qHTS	D1_inhibitors	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=94c9b1cf-ae12-45f3-8fcb-708a922cbc10	1	LoF	protect
Allosteric Agonists of the Human D1 Dopamine Receptor: qHTS	D1_activators	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b4c5f70e-da62-4d1d-a3e0-6fe5e45bb65b	1	LoF	protect
Allosteric Modulators of D1 Receptors: Primary Screen	D1	DRD1	Dopamine receptor D1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b4c5f70e-da62-4d1d-a3e0-6fe5e45bb65b	1	LoF	protect
Antagonist of Human D 1 Dopamine Receptor: qHTS	D1_inhibitors	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b4c5f70e-da62-4d1d-a3e0-6fe5e45bb65b	1	LoF	protect
Allosteric Agonists of the Human D1 Dopamine Receptor: qHTS	D1_activators	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2233bd51-ca5a-415a-99b6-b294e55d2847	1	LoF	protect
Allosteric Modulators of D1 Receptors: Primary Screen	D1	DRD1	Dopamine receptor D1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2233bd51-ca5a-415a-99b6-b294e55d2847	1	LoF	protect
Antagonist of Human D 1 Dopamine Receptor: qHTS	D1_inhibitors	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2233bd51-ca5a-415a-99b6-b294e55d2847	1	LoF	protect
Allosteric Agonists of the Human D1 Dopamine Receptor: qHTS	D1_activators	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4	Completed	01/03/2015	https://clinicaltrials.gov/study/NCT02408965	1	LoF	protect
Allosteric Modulators of D1 Receptors: Primary Screen	D1	DRD1	Dopamine receptor D1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4	Completed	01/03/2015	https://clinicaltrials.gov/study/NCT02408965	1	LoF	protect
Antagonist of Human D 1 Dopamine Receptor: qHTS	D1_inhibitors	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4	Completed	01/03/2015	https://clinicaltrials.gov/study/NCT02408965	1	LoF	protect
Allosteric Agonists of the Human D1 Dopamine Receptor: qHTS	D1_activators	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a9a3079e-b62b-4858-920e-d8f5cb38481e	1	LoF	protect
Allosteric Modulators of D1 Receptors: Primary Screen	D1	DRD1	Dopamine receptor D1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a9a3079e-b62b-4858-920e-d8f5cb38481e	1	LoF	protect
Antagonist of Human D 1 Dopamine Receptor: qHTS	D1_inhibitors	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a9a3079e-b62b-4858-920e-d8f5cb38481e	1	LoF	protect
Allosteric Agonists of the Human D1 Dopamine Receptor: qHTS	D1_activators	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=f617b954-71b9-4bef-aeb2-f87eb9f04ef6	1	LoF	protect
Allosteric Modulators of D1 Receptors: Primary Screen	D1	DRD1	Dopamine receptor D1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=f617b954-71b9-4bef-aeb2-f87eb9f04ef6	1	LoF	protect
Antagonist of Human D 1 Dopamine Receptor: qHTS	D1_inhibitors	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=f617b954-71b9-4bef-aeb2-f87eb9f04ef6	1	LoF	protect
Allosteric Agonists of the Human D1 Dopamine Receptor: qHTS	D1_activators	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=17ee0c79-ac98-4400-ae77-985978fca07e	1	LoF	protect
Allosteric Modulators of D1 Receptors: Primary Screen	D1	DRD1	Dopamine receptor D1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=17ee0c79-ac98-4400-ae77-985978fca07e	1	LoF	protect
Antagonist of Human D 1 Dopamine Receptor: qHTS	D1_inhibitors	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=17ee0c79-ac98-4400-ae77-985978fca07e	1	LoF	protect
Allosteric Agonists of the Human D1 Dopamine Receptor: qHTS	D1_activators	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=047d3ab6-1f93-4080-95c1-f938ce8d5532	1	LoF	protect
Allosteric Modulators of D1 Receptors: Primary Screen	D1	DRD1	Dopamine receptor D1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=047d3ab6-1f93-4080-95c1-f938ce8d5532	1	LoF	protect
Antagonist of Human D 1 Dopamine Receptor: qHTS	D1_inhibitors	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=047d3ab6-1f93-4080-95c1-f938ce8d5532	1	LoF	protect
Allosteric Agonists of the Human D1 Dopamine Receptor: qHTS	D1_activators	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=70106231-37f5-3e64-e053-2991aa0ab9af	1	LoF	protect
Allosteric Modulators of D1 Receptors: Primary Screen	D1	DRD1	Dopamine receptor D1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=70106231-37f5-3e64-e053-2991aa0ab9af	1	LoF	protect
Antagonist of Human D 1 Dopamine Receptor: qHTS	D1_inhibitors	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=70106231-37f5-3e64-e053-2991aa0ab9af	1	LoF	protect
Allosteric Agonists of the Human D1 Dopamine Receptor: qHTS	D1_activators	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4	Completed	01/05/2014	https://clinicaltrials.gov/study/NCT02101567	1	LoF	protect
Allosteric Modulators of D1 Receptors: Primary Screen	D1	DRD1	Dopamine receptor D1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4	Completed	01/05/2014	https://clinicaltrials.gov/study/NCT02101567	1	LoF	protect
Antagonist of Human D 1 Dopamine Receptor: qHTS	D1_inhibitors	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4	Completed	01/05/2014	https://clinicaltrials.gov/study/NCT02101567	1	LoF	protect
Allosteric Agonists of the Human D1 Dopamine Receptor: qHTS	D1_activators	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=fa75ef56-dcf4-4c3e-bea4-161893e09685	1	LoF	protect
Allosteric Modulators of D1 Receptors: Primary Screen	D1	DRD1	Dopamine receptor D1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=fa75ef56-dcf4-4c3e-bea4-161893e09685	1	LoF	protect
Antagonist of Human D 1 Dopamine Receptor: qHTS	D1_inhibitors	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=fa75ef56-dcf4-4c3e-bea4-161893e09685	1	LoF	protect
Allosteric Agonists of the Human D1 Dopamine Receptor: qHTS	D1_activators	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=fde7483c-1c37-43f0-b905-c68fcc05a6fd	1	LoF	protect
Allosteric Modulators of D1 Receptors: Primary Screen	D1	DRD1	Dopamine receptor D1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=fde7483c-1c37-43f0-b905-c68fcc05a6fd	1	LoF	protect
Antagonist of Human D 1 Dopamine Receptor: qHTS	D1_inhibitors	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=fde7483c-1c37-43f0-b905-c68fcc05a6fd	1	LoF	protect
Allosteric Agonists of the Human D1 Dopamine Receptor: qHTS	D1_activators	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b1552d48-86f5-4184-810a-001e57e96c02	1	LoF	protect
Allosteric Modulators of D1 Receptors: Primary Screen	D1	DRD1	Dopamine receptor D1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b1552d48-86f5-4184-810a-001e57e96c02	1	LoF	protect
Antagonist of Human D 1 Dopamine Receptor: qHTS	D1_inhibitors	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b1552d48-86f5-4184-810a-001e57e96c02	1	LoF	protect
Allosteric Agonists of the Human D1 Dopamine Receptor: qHTS	D1_activators	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7929b3cf-2902-438a-954f-c5c950e0e402	1	LoF	protect
Allosteric Modulators of D1 Receptors: Primary Screen	D1	DRD1	Dopamine receptor D1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7929b3cf-2902-438a-954f-c5c950e0e402	1	LoF	protect
Antagonist of Human D 1 Dopamine Receptor: qHTS	D1_inhibitors	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7929b3cf-2902-438a-954f-c5c950e0e402	1	LoF	protect
Allosteric Agonists of the Human D1 Dopamine Receptor: qHTS	D1_activators	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=47fd2922-5b1e-4995-8324-ecd495a160e1	1	LoF	protect
Allosteric Modulators of D1 Receptors: Primary Screen	D1	DRD1	Dopamine receptor D1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=47fd2922-5b1e-4995-8324-ecd495a160e1	1	LoF	protect
Antagonist of Human D 1 Dopamine Receptor: qHTS	D1_inhibitors	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=47fd2922-5b1e-4995-8324-ecd495a160e1	1	LoF	protect
Allosteric Agonists of the Human D1 Dopamine Receptor: qHTS	D1_activators	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=83e4cc2a-a0df-41e4-955d-ee51f29c68cc	1	LoF	protect
Allosteric Modulators of D1 Receptors: Primary Screen	D1	DRD1	Dopamine receptor D1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=83e4cc2a-a0df-41e4-955d-ee51f29c68cc	1	LoF	protect
Antagonist of Human D 1 Dopamine Receptor: qHTS	D1_inhibitors	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE MALEATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=83e4cc2a-a0df-41e4-955d-ee51f29c68cc	1	LoF	protect
Fluorescence-based cell-based primary high throughput screening assay to identify agonists of the human cholinergic receptor, muscarinic 1 (CHRM1)	CHRM1_agonists	CHRM1	Muscarinic acetylcholine receptor M1	blood coagulation	GLYCOPYRROLATE	targetBased	3	Completed	12/10/2011	https://clinicaltrials.gov/study/NCT01422304	0.7	LoF	protect
Discovery of Novel Allosteric Modulators of the M1 Muscarinic Receptor: Agonist Primary Screen	CHRM1_allosteric_activators	CHRM1	Muscarinic acetylcholine receptor M1	blood coagulation	GLYCOPYRROLATE	targetBased	3	Completed	12/10/2011	https://clinicaltrials.gov/study/NCT01422304	0.7	LoF	protect
Fluorescence-based cell-based primary high throughput screening assay to identify positive allosteric modulators (PAMs) of the human M1 muscarinic receptor (CHRM1).	CHRM1_PAMs	CHRM1	Muscarinic acetylcholine receptor M1	blood coagulation	GLYCOPYRROLATE	targetBased	3	Completed	12/10/2011	https://clinicaltrials.gov/study/NCT01422304	0.7	LoF	protect
Discovery of novel allosteric modulators of the M1 muscarinic receptor: Antagonist Primary Screen	CHRM1_allosteric_antagonists	CHRM1	Muscarinic acetylcholine receptor M1	blood coagulation	GLYCOPYRROLATE	targetBased	3	Completed	12/10/2011	https://clinicaltrials.gov/study/NCT01422304	0.7	LoF	protect
Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the human M1 muscarinic receptor (CHRM1)	CHRM1_antgonists	CHRM1	Muscarinic acetylcholine receptor M1	blood coagulation	GLYCOPYRROLATE	targetBased	3	Completed	12/10/2011	https://clinicaltrials.gov/study/NCT01422304	0.7	LoF	protect
uHTS identification of DNMT1 inhibitors in a Fluorescent Molecular Beacon assay	DNMT1	DNMT1	DNA methyltransferase-1	Abnormality of blood and blood-forming tissues	DECITABINE	targetBased	3	Completed	01/10/2015	https://clinicaltrials.gov/study/NCT02487563	0.7	LoF	protect
uHTS identification of DNMT1 inhibitors in a Fluorescent Molecular Beacon assay	DNMT1	DNMT1	DNA methyltransferase-1	anemia	DECITABINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=91a0f80b-f865-4d06-a40d-4d148d99ee71	1	LoF	protect
uHTS identification of DNMT1 inhibitors in a Fluorescent Molecular Beacon assay	DNMT1	DNMT1	DNA methyltransferase-1	anemia	DECITABINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=deb4a13c-855b-4372-9778-6e81da598df6	1	LoF	protect
uHTS identification of DNMT1 inhibitors in a Fluorescent Molecular Beacon assay	DNMT1	DNMT1	DNA methyltransferase-1	Thrombocytopenia	DECITABINE	targetBased	3	Completed	01/10/2015	https://clinicaltrials.gov/study/NCT02487563	0.7	LoF	protect
uHTS identification of DNMT1 inhibitors in a Fluorescent Molecular Beacon assay	DNMT1	DNMT1	DNA methyltransferase-1	Thalassemia	DECITABINE	targetBased	2	Completed	01/01/2008	https://clinicaltrials.gov/study/NCT00661726	0.2	LoF	protect
Fluorescence-based cell-based primary high throughput screening assay to identify positive allosteric modulators (PAMs) of the human cholinergic receptor, muscarinic 4 (CHRM4)	CHRM4_PAMs	CHRM4	Muscarinic acetylcholine receptor M4	blood coagulation	GLYCOPYRRONIUM	targetBased	3	Completed	12/10/2011	https://clinicaltrials.gov/study/NCT01422304	0.7	LoF	protect
Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the human cholinergic receptor, muscarinic 4 (CHRM4)	CHRM4_antgonists	CHRM4	Muscarinic acetylcholine receptor M4	blood coagulation	GLYCOPYRRONIUM	targetBased	3	Completed	12/10/2011	https://clinicaltrials.gov/study/NCT01422304	0.7	LoF	protect
Fluorescence-based cell-based primary high throughput screening assay to identify agonists of the human cholinergic receptor, muscarinic 4 (CHRM4)	CHRM4_agonists	CHRM4	Muscarinic acetylcholine receptor M4	blood coagulation	GLYCOPYRRONIUM	targetBased	3	Completed	12/10/2011	https://clinicaltrials.gov/study/NCT01422304	0.7	LoF	protect
Fluorescence-based cell-based primary high throughput screening assay to identify agonists of the human cholinergic receptor, muscarinic 1 (CHRM1)	CHRM1_agonists	CHRM1	Muscarinic acetylcholine receptor M1	blood coagulation	GLYCOPYRRONIUM	targetBased	3	Completed	12/10/2011	https://clinicaltrials.gov/study/NCT01422304	0.7	LoF	protect
Discovery of Novel Allosteric Modulators of the M1 Muscarinic Receptor: Agonist Primary Screen	CHRM1_allosteric_activators	CHRM1	Muscarinic acetylcholine receptor M1	blood coagulation	GLYCOPYRRONIUM	targetBased	3	Completed	12/10/2011	https://clinicaltrials.gov/study/NCT01422304	0.7	LoF	protect
Fluorescence-based cell-based primary high throughput screening assay to identify positive allosteric modulators (PAMs) of the human M1 muscarinic receptor (CHRM1).	CHRM1_PAMs	CHRM1	Muscarinic acetylcholine receptor M1	blood coagulation	GLYCOPYRRONIUM	targetBased	3	Completed	12/10/2011	https://clinicaltrials.gov/study/NCT01422304	0.7	LoF	protect
Discovery of novel allosteric modulators of the M1 muscarinic receptor: Antagonist Primary Screen	CHRM1_allosteric_antagonists	CHRM1	Muscarinic acetylcholine receptor M1	blood coagulation	GLYCOPYRRONIUM	targetBased	3	Completed	12/10/2011	https://clinicaltrials.gov/study/NCT01422304	0.7	LoF	protect
Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the human M1 muscarinic receptor (CHRM1)	CHRM1_antgonists	CHRM1	Muscarinic acetylcholine receptor M1	blood coagulation	GLYCOPYRRONIUM	targetBased	3	Completed	12/10/2011	https://clinicaltrials.gov/study/NCT01422304	0.7	LoF	protect
Fluorescence-based cell-based primary high throughput screening assay to identify agonists of the human cholinergic receptor, muscarinic 5 (CHRM5)	CHRM5	CHRM5	Muscarinic acetylcholine receptor M5	blood coagulation	GLYCOPYRRONIUM	targetBased	3	Completed	12/10/2011	https://clinicaltrials.gov/study/NCT01422304	0.7	LoF	protect
Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the human cholinergic receptor, muscarinic 5 (CHRM5)	CHRM5	CHRM5	Muscarinic acetylcholine receptor M5	blood coagulation	GLYCOPYRRONIUM	targetBased	3	Completed	12/10/2011	https://clinicaltrials.gov/study/NCT01422304	0.7	LoF	protect
Fluorescence-based cell-based primary high throughput screening assay to identify positive allosteric modulators (PAMs) of the human cholinergic receptor, muscarinic 5 (CHRM5)	CHRM5	CHRM5	Muscarinic acetylcholine receptor M5	blood coagulation	GLYCOPYRRONIUM	targetBased	3	Completed	12/10/2011	https://clinicaltrials.gov/study/NCT01422304	0.7	LoF	protect
Allosteric Agonists of the Human D1 Dopamine Receptor: qHTS	D1_activators	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b1552d48-86f5-4184-810a-001e57e96c02	1	LoF	protect
Allosteric Modulators of D1 Receptors: Primary Screen	D1	DRD1	Dopamine receptor D1	hemorrhage	METHYLERGONOVINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b1552d48-86f5-4184-810a-001e57e96c02	1	LoF	protect
Antagonist of Human D 1 Dopamine Receptor: qHTS	D1_inhibitors	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b1552d48-86f5-4184-810a-001e57e96c02	1	LoF	protect
Allosteric Agonists of the Human D1 Dopamine Receptor: qHTS	D1_activators	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=f617b954-71b9-4bef-aeb2-f87eb9f04ef6	1	LoF	protect
Allosteric Modulators of D1 Receptors: Primary Screen	D1	DRD1	Dopamine receptor D1	hemorrhage	METHYLERGONOVINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=f617b954-71b9-4bef-aeb2-f87eb9f04ef6	1	LoF	protect
Antagonist of Human D 1 Dopamine Receptor: qHTS	D1_inhibitors	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=f617b954-71b9-4bef-aeb2-f87eb9f04ef6	1	LoF	protect
Allosteric Agonists of the Human D1 Dopamine Receptor: qHTS	D1_activators	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE	targetBased	4	Completed	01/03/2015	https://clinicaltrials.gov/study/NCT02408965	1	LoF	protect
Allosteric Modulators of D1 Receptors: Primary Screen	D1	DRD1	Dopamine receptor D1	hemorrhage	METHYLERGONOVINE	targetBased	4	Completed	01/03/2015	https://clinicaltrials.gov/study/NCT02408965	1	LoF	protect
Antagonist of Human D 1 Dopamine Receptor: qHTS	D1_inhibitors	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE	targetBased	4	Completed	01/03/2015	https://clinicaltrials.gov/study/NCT02408965	1	LoF	protect
Allosteric Agonists of the Human D1 Dopamine Receptor: qHTS	D1_activators	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b91d1729-2e8e-4398-9a0d-02763bcfe284	1	LoF	protect
Allosteric Modulators of D1 Receptors: Primary Screen	D1	DRD1	Dopamine receptor D1	hemorrhage	METHYLERGONOVINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b91d1729-2e8e-4398-9a0d-02763bcfe284	1	LoF	protect
Antagonist of Human D 1 Dopamine Receptor: qHTS	D1_inhibitors	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b91d1729-2e8e-4398-9a0d-02763bcfe284	1	LoF	protect
Allosteric Agonists of the Human D1 Dopamine Receptor: qHTS	D1_activators	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=17ee0c79-ac98-4400-ae77-985978fca07e	1	LoF	protect
Allosteric Modulators of D1 Receptors: Primary Screen	D1	DRD1	Dopamine receptor D1	hemorrhage	METHYLERGONOVINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=17ee0c79-ac98-4400-ae77-985978fca07e	1	LoF	protect
Antagonist of Human D 1 Dopamine Receptor: qHTS	D1_inhibitors	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=17ee0c79-ac98-4400-ae77-985978fca07e	1	LoF	protect
Allosteric Agonists of the Human D1 Dopamine Receptor: qHTS	D1_activators	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=fde7483c-1c37-43f0-b905-c68fcc05a6fd	1	LoF	protect
Allosteric Modulators of D1 Receptors: Primary Screen	D1	DRD1	Dopamine receptor D1	hemorrhage	METHYLERGONOVINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=fde7483c-1c37-43f0-b905-c68fcc05a6fd	1	LoF	protect
Antagonist of Human D 1 Dopamine Receptor: qHTS	D1_inhibitors	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=fde7483c-1c37-43f0-b905-c68fcc05a6fd	1	LoF	protect
Allosteric Agonists of the Human D1 Dopamine Receptor: qHTS	D1_activators	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2233bd51-ca5a-415a-99b6-b294e55d2847	1	LoF	protect
Allosteric Modulators of D1 Receptors: Primary Screen	D1	DRD1	Dopamine receptor D1	hemorrhage	METHYLERGONOVINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2233bd51-ca5a-415a-99b6-b294e55d2847	1	LoF	protect
Antagonist of Human D 1 Dopamine Receptor: qHTS	D1_inhibitors	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2233bd51-ca5a-415a-99b6-b294e55d2847	1	LoF	protect
Allosteric Agonists of the Human D1 Dopamine Receptor: qHTS	D1_activators	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=047d3ab6-1f93-4080-95c1-f938ce8d5532	1	LoF	protect
Allosteric Modulators of D1 Receptors: Primary Screen	D1	DRD1	Dopamine receptor D1	hemorrhage	METHYLERGONOVINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=047d3ab6-1f93-4080-95c1-f938ce8d5532	1	LoF	protect
Antagonist of Human D 1 Dopamine Receptor: qHTS	D1_inhibitors	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=047d3ab6-1f93-4080-95c1-f938ce8d5532	1	LoF	protect
Allosteric Agonists of the Human D1 Dopamine Receptor: qHTS	D1_activators	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=47fd2922-5b1e-4995-8324-ecd495a160e1	1	LoF	protect
Allosteric Modulators of D1 Receptors: Primary Screen	D1	DRD1	Dopamine receptor D1	hemorrhage	METHYLERGONOVINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=47fd2922-5b1e-4995-8324-ecd495a160e1	1	LoF	protect
Antagonist of Human D 1 Dopamine Receptor: qHTS	D1_inhibitors	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=47fd2922-5b1e-4995-8324-ecd495a160e1	1	LoF	protect
Allosteric Agonists of the Human D1 Dopamine Receptor: qHTS	D1_activators	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b4c5f70e-da62-4d1d-a3e0-6fe5e45bb65b	1	LoF	protect
Allosteric Modulators of D1 Receptors: Primary Screen	D1	DRD1	Dopamine receptor D1	hemorrhage	METHYLERGONOVINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b4c5f70e-da62-4d1d-a3e0-6fe5e45bb65b	1	LoF	protect
Antagonist of Human D 1 Dopamine Receptor: qHTS	D1_inhibitors	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b4c5f70e-da62-4d1d-a3e0-6fe5e45bb65b	1	LoF	protect
Allosteric Agonists of the Human D1 Dopamine Receptor: qHTS	D1_activators	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=53179d26-7dda-4770-a312-37e28f2dc375	1	LoF	protect
Allosteric Modulators of D1 Receptors: Primary Screen	D1	DRD1	Dopamine receptor D1	hemorrhage	METHYLERGONOVINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=53179d26-7dda-4770-a312-37e28f2dc375	1	LoF	protect
Antagonist of Human D 1 Dopamine Receptor: qHTS	D1_inhibitors	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=53179d26-7dda-4770-a312-37e28f2dc375	1	LoF	protect
Allosteric Agonists of the Human D1 Dopamine Receptor: qHTS	D1_activators	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=83e4cc2a-a0df-41e4-955d-ee51f29c68cc	1	LoF	protect
Allosteric Modulators of D1 Receptors: Primary Screen	D1	DRD1	Dopamine receptor D1	hemorrhage	METHYLERGONOVINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=83e4cc2a-a0df-41e4-955d-ee51f29c68cc	1	LoF	protect
Antagonist of Human D 1 Dopamine Receptor: qHTS	D1_inhibitors	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=83e4cc2a-a0df-41e4-955d-ee51f29c68cc	1	LoF	protect
Allosteric Agonists of the Human D1 Dopamine Receptor: qHTS	D1_activators	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=70106231-37f5-3e64-e053-2991aa0ab9af	1	LoF	protect
Allosteric Modulators of D1 Receptors: Primary Screen	D1	DRD1	Dopamine receptor D1	hemorrhage	METHYLERGONOVINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=70106231-37f5-3e64-e053-2991aa0ab9af	1	LoF	protect
Antagonist of Human D 1 Dopamine Receptor: qHTS	D1_inhibitors	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=70106231-37f5-3e64-e053-2991aa0ab9af	1	LoF	protect
Allosteric Agonists of the Human D1 Dopamine Receptor: qHTS	D1_activators	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a9a3079e-b62b-4858-920e-d8f5cb38481e	1	LoF	protect
Allosteric Modulators of D1 Receptors: Primary Screen	D1	DRD1	Dopamine receptor D1	hemorrhage	METHYLERGONOVINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a9a3079e-b62b-4858-920e-d8f5cb38481e	1	LoF	protect
Antagonist of Human D 1 Dopamine Receptor: qHTS	D1_inhibitors	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a9a3079e-b62b-4858-920e-d8f5cb38481e	1	LoF	protect
Allosteric Agonists of the Human D1 Dopamine Receptor: qHTS	D1_activators	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE	targetBased	4	Completed	01/05/2014	https://clinicaltrials.gov/study/NCT02101567	1	LoF	protect
Allosteric Modulators of D1 Receptors: Primary Screen	D1	DRD1	Dopamine receptor D1	hemorrhage	METHYLERGONOVINE	targetBased	4	Completed	01/05/2014	https://clinicaltrials.gov/study/NCT02101567	1	LoF	protect
Antagonist of Human D 1 Dopamine Receptor: qHTS	D1_inhibitors	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE	targetBased	4	Completed	01/05/2014	https://clinicaltrials.gov/study/NCT02101567	1	LoF	protect
Allosteric Agonists of the Human D1 Dopamine Receptor: qHTS	D1_activators	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=94c9b1cf-ae12-45f3-8fcb-708a922cbc10	1	LoF	protect
Allosteric Modulators of D1 Receptors: Primary Screen	D1	DRD1	Dopamine receptor D1	hemorrhage	METHYLERGONOVINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=94c9b1cf-ae12-45f3-8fcb-708a922cbc10	1	LoF	protect
Antagonist of Human D 1 Dopamine Receptor: qHTS	D1_inhibitors	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=94c9b1cf-ae12-45f3-8fcb-708a922cbc10	1	LoF	protect
Allosteric Agonists of the Human D1 Dopamine Receptor: qHTS	D1_activators	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7929b3cf-2902-438a-954f-c5c950e0e402	1	LoF	protect
Allosteric Modulators of D1 Receptors: Primary Screen	D1	DRD1	Dopamine receptor D1	hemorrhage	METHYLERGONOVINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7929b3cf-2902-438a-954f-c5c950e0e402	1	LoF	protect
Antagonist of Human D 1 Dopamine Receptor: qHTS	D1_inhibitors	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7929b3cf-2902-438a-954f-c5c950e0e402	1	LoF	protect
Allosteric Agonists of the Human D1 Dopamine Receptor: qHTS	D1_activators	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=fa75ef56-dcf4-4c3e-bea4-161893e09685	1	LoF	protect
Allosteric Modulators of D1 Receptors: Primary Screen	D1	DRD1	Dopamine receptor D1	hemorrhage	METHYLERGONOVINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=fa75ef56-dcf4-4c3e-bea4-161893e09685	1	LoF	protect
Antagonist of Human D 1 Dopamine Receptor: qHTS	D1_inhibitors	DRD1	Dopaminereceptor1	hemorrhage	METHYLERGONOVINE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=fa75ef56-dcf4-4c3e-bea4-161893e09685	1	LoF	protect
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	Thromboembolism	LEPIRUDIN	targetBased	4			https://www.ema.europa.eu/en/medicines/human/EPAR/refludan	1	LoF	protect
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	Recurrent thrombophlebitis	LEPIRUDIN	targetBased	4			https://www.whocc.no/atc_ddd_index/?code=B01AE02	1	LoF	protect
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	Thrombocytopenia	LEPIRUDIN	targetBased	4			https://www.ema.europa.eu/en/medicines/human/EPAR/refludan	1	LoF	protect
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	Thrombocytopenia	LEPIRUDIN	targetBased	4	Withdrawn	01/01/2008	https://clinicaltrials.gov/study/NCT00603824	1	LoF	protect	PI relocated
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	Thrombocytopenia	LEPIRUDIN	targetBased	4	Terminated	01/01/2009	https://clinicaltrials.gov/study/NCT00798525	1	LoF	protect	Supply of Lepirudin ended on 01. April 2012, thus trial terminated on 31. March 2012
qHTS for Inhibitors of Cell Surface uPA Generation	PLAU	PLAU	Urokinase-type plasminogen activator	Recurrent thrombophlebitis	UROKINASE	targetBased	4			https://www.whocc.no/atc_ddd_index/?code=B01AD04	1		protect
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	FGB_inhibitors	FGB	Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]	Recurrent thrombophlebitis	FIBRINOLYSIN, HUMAN	targetBased	4			https://www.whocc.no/atc_ddd_index/?code=B01AD05	1	LoF	protect
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	FGB_inhibitors	FGB	Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]	Recurrent thrombophlebitis	FIBRINOLYSIN, HUMAN	targetBased	4			https://www.whocc.no/atc_ddd_index/?code=B01AD05	1	LoF	protect
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	deep vein thrombosis	DESIRUDIN	targetBased	2	Completed	01/05/2006	https://clinicaltrials.gov/study/NCT00329433	0.2	LoF	protect
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	deep vein thrombosis	DESIRUDIN	targetBased	4			https://www.accessdata.fda.gov/drugsatfda_docs/label/2003/021271lbl.pdf	1	LoF	protect
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	Venous thrombosis	DESIRUDIN	targetBased	4			https://www.ema.europa.eu/en/medicines/human/EPAR/revasc	1	LoF	protect
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	Recurrent thrombophlebitis	DESIRUDIN	targetBased	4			https://www.whocc.no/atc_ddd_index/?code=B01AE01	1	LoF	protect
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	Thrombocytopenia	DESIRUDIN	targetBased	4	Terminated	01/09/2008	https://clinicaltrials.gov/study/NCT00787332	1	LoF	protect	Low enrollment
HTS for Estrogen Receptor-beta Coactivator Binding inhibitors	ESR2_inhibitors	ESR2	Estrogen receptor beta	Microscopic hematuria	ESTROGENS, CONJUGATED	targetBased	4	Terminated	01/08/2014	https://clinicaltrials.gov/study/NCT02213757	1	GoF	protect	Low Enrollment
HTS of Estrogen Receptor- alpha Coactivator Binding inhibitors	ESR1_inhibitors	ESR1	Estrogen receptor, Estrogen receptor	Microscopic hematuria	ESTROGENS, CONJUGATED	targetBased	4	Terminated	01/08/2014	https://clinicaltrials.gov/study/NCT02213757	1	GoF	protect	Low Enrollment
HTS of Estrogen Receptor- alpha Coactivator Binding Potentiators	ESR1_modulators	ESR1	Estrogen receptor, Estrogen receptor	Microscopic hematuria	ESTROGENS, CONJUGATED	targetBased	4	Terminated	01/08/2014	https://clinicaltrials.gov/study/NCT02213757	1	GoF	protect	Low Enrollment
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	deep vein thrombosis	DABIGATRAN ETEXILATE MESYLATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ba74e3cd-b06f-4145-b284-5fd6b84ff3c9	1	LoF	protect
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F	JAK2	JAK2	Tyrosine-protein kinase , Tyrosine-protein kinase JAK2	anemia (phenotype)	RUXOLITINIB	targetBased	2	Completed	21/02/2013	https://clinicaltrials.gov/study/NCT01712308	0.2	LoF	protect
Fluorescence-based biochemical primary high throughput screening assay to identify activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF)	TNNI3	TNNI3	Troponin I, cardiac muscle	hemorrhage	LEVOSIMENDAN	targetBased	2	Recruiting	13/10/2023	https://clinicaltrials.gov/study/NCT05664191	0.2	GoF	protect
Fluorescence-based biochemical primary high throughput screening assay to identify inhibitors of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF)	TNNI3	TNNI3	Troponin I, cardiac muscle	hemorrhage	LEVOSIMENDAN	targetBased	2	Recruiting	13/10/2023	https://clinicaltrials.gov/study/NCT05664191	0.2	GoF	protect
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	FGB_inhibitors	FGB	Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]	hypoplasminogenemia	PLASMINOGEN	targetBased	2	Completed	22/05/2013	https://clinicaltrials.gov/study/NCT01554956	0.2		protect
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	FGB_inhibitors	FGB	Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]	hypoplasminogenemia	PLASMINOGEN	targetBased	2	Completed	22/05/2013	https://clinicaltrials.gov/study/NCT01554956	0.2		protect
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	FGB_inhibitors	FGB	Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]	hypoplasminogenemia	PLASMINOGEN	targetBased	2	Completed	04/05/2016	https://clinicaltrials.gov/study/NCT02690714	0.2		protect
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	FGB_inhibitors	FGB	Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]	hypoplasminogenemia	PLASMINOGEN	targetBased	2	Completed	04/05/2016	https://clinicaltrials.gov/study/NCT02690714	0.2		protect
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	FGB_inhibitors	FGB	Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]	Recurrent thrombophlebitis	ANCROD	targetBased	3			https://www.whocc.no/atc_ddd_index/?code=B01AD09	0.7		protect
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	FGB_inhibitors	FGB	Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]	Recurrent thrombophlebitis	ANCROD	targetBased	3			https://www.whocc.no/atc_ddd_index/?code=B01AD09	0.7		protect
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	FGB_inhibitors	FGB	Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]	Venous thrombosis	ALFIMEPRASE	targetBased	3	Completed	01/09/2005	https://clinicaltrials.gov/study/NCT00346424	0.7		protect
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	FGB_inhibitors	FGB	Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]	Venous thrombosis	ALFIMEPRASE	targetBased	3	Completed	01/09/2005	https://clinicaltrials.gov/study/NCT00346424	0.7		protect
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	FGB_inhibitors	FGB	Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]	Venous thrombosis	ALFIMEPRASE	targetBased	2	Completed		https://clinicaltrials.gov/study/NCT00073515	0.2		protect
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	FGB_inhibitors	FGB	Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]	Venous thrombosis	ALFIMEPRASE	targetBased	2	Completed		https://clinicaltrials.gov/study/NCT00073515	0.2		protect
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	FGB_inhibitors	FGB	Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]	congenital afibrinogenemia	FIBRINOGEN, HUMAN	targetBased	3	Completed	01/03/2013	https://clinicaltrials.gov/study/NCT02065882	0.7		protect
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	FGB_inhibitors	FGB	Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]	congenital afibrinogenemia	FIBRINOGEN, HUMAN	targetBased	3	Completed	01/03/2013	https://clinicaltrials.gov/study/NCT02065882	0.7		protect
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	FGB_inhibitors	FGB	Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]	Abnormality of blood and blood-forming tissues	FIBRINOGEN, HUMAN	targetBased	2	Completed	01/08/2010	https://clinicaltrials.gov/study/NCT01187225	0.2		protect
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	FGB_inhibitors	FGB	Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]	Abnormality of blood and blood-forming tissues	FIBRINOGEN, HUMAN	targetBased	2	Completed	01/08/2010	https://clinicaltrials.gov/study/NCT01187225	0.2		protect
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	FGB_inhibitors	FGB	Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]	congenital fibrinogen deficiency	FIBRINOGEN, HUMAN	targetBased	2	Completed	01/07/2007	https://clinicaltrials.gov/study/NCT00496262	0.2		protect
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	FGB_inhibitors	FGB	Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]	congenital fibrinogen deficiency	FIBRINOGEN, HUMAN	targetBased	2	Completed	01/07/2007	https://clinicaltrials.gov/study/NCT00496262	0.2		protect
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	FGB_inhibitors	FGB	Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]	Hypofibrinogenemia	FIBRINOGEN, HUMAN	targetBased	4	Unknown status	01/03/2019	https://clinicaltrials.gov/study/NCT03884725	1		protect
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	FGB_inhibitors	FGB	Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]	Hypofibrinogenemia	FIBRINOGEN, HUMAN	targetBased	4	Unknown status	01/03/2019	https://clinicaltrials.gov/study/NCT03884725	1		protect
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	FGB_inhibitors	FGB	Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]	Hypofibrinogenemia	FIBRINOGEN, HUMAN	targetBased	2	Completed	01/01/2014	https://clinicaltrials.gov/study/NCT02094430	0.2		protect
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	FGB_inhibitors	FGB	Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]	Hypofibrinogenemia	FIBRINOGEN, HUMAN	targetBased	2	Completed	01/01/2014	https://clinicaltrials.gov/study/NCT02094430	0.2		protect
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	FGB_inhibitors	FGB	Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]	Hypofibrinogenemia	FIBRINOGEN, HUMAN	targetBased	3	Completed	01/03/2013	https://clinicaltrials.gov/study/NCT02065882	0.7		protect
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	FGB_inhibitors	FGB	Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]	Hypofibrinogenemia	FIBRINOGEN, HUMAN	targetBased	3	Completed	01/03/2013	https://clinicaltrials.gov/study/NCT02065882	0.7		protect
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	FGB_inhibitors	FGB	Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]	hemorrhage	FIBRINOGEN, HUMAN	targetBased	4	Terminated	01/08/2014	https://clinicaltrials.gov/study/NCT02299947	1		protect	Slow inclusion
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	FGB_inhibitors	FGB	Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]	hemorrhage	FIBRINOGEN, HUMAN	targetBased	4	Terminated	01/08/2014	https://clinicaltrials.gov/study/NCT02299947	1		protect	Slow inclusion
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	FGB_inhibitors	FGB	Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]	hemorrhage	FIBRINOGEN, HUMAN	targetBased	4	Completed	01/01/2012	https://clinicaltrials.gov/study/NCT01487837	1		protect
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	FGB_inhibitors	FGB	Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]	hemorrhage	FIBRINOGEN, HUMAN	targetBased	4	Completed	01/01/2012	https://clinicaltrials.gov/study/NCT01487837	1		protect
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	FGB_inhibitors	FGB	Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]	hemorrhage	FIBRINOGEN, HUMAN	targetBased	3	Completed	01/07/2014	https://clinicaltrials.gov/study/NCT02227992	0.7		protect
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	FGB_inhibitors	FGB	Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]	hemorrhage	FIBRINOGEN, HUMAN	targetBased	3	Completed	01/07/2014	https://clinicaltrials.gov/study/NCT02227992	0.7		protect
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	FGB_inhibitors	FGB	Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]	hemorrhage	FIBRINOGEN, HUMAN	targetBased	3	Unknown status	01/07/2012	https://clinicaltrials.gov/study/NCT01539057	0.7		protect
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	FGB_inhibitors	FGB	Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]	hemorrhage	FIBRINOGEN, HUMAN	targetBased	3	Unknown status	01/07/2012	https://clinicaltrials.gov/study/NCT01539057	0.7		protect
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	FGB_inhibitors	FGB	Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]	hemorrhage	FIBRINOGEN, HUMAN	targetBased	3	Completed	01/01/2012	https://clinicaltrials.gov/study/NCT01475669	0.7		protect
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	FGB_inhibitors	FGB	Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]	hemorrhage	FIBRINOGEN, HUMAN	targetBased	3	Completed	01/01/2012	https://clinicaltrials.gov/study/NCT01475669	0.7		protect
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	FGB_inhibitors	FGB	Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]	hemorrhage	FIBRINOGEN, HUMAN	targetBased	4	Completed	01/02/2007	https://clinicaltrials.gov/study/NCT00440401	1		protect
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	FGB_inhibitors	FGB	Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]	hemorrhage	FIBRINOGEN, HUMAN	targetBased	4	Completed	01/02/2007	https://clinicaltrials.gov/study/NCT00440401	1		protect
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	FGB_inhibitors	FGB	Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]	hemorrhage	FIBRINOGEN, HUMAN	targetBased	2	Recruiting	10/02/2022	https://clinicaltrials.gov/study/NCT05091684	0.2		protect
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	FGB_inhibitors	FGB	Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]	hemorrhage	FIBRINOGEN, HUMAN	targetBased	2	Recruiting	10/02/2022	https://clinicaltrials.gov/study/NCT05091684	0.2		protect
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	FGB_inhibitors	FGB	Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]	hemorrhage	FIBRINOGEN, HUMAN	targetBased	3			https://www.whocc.no/atc_ddd_index/?code=B02BB01	0.7		protect
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	FGB_inhibitors	FGB	Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]	hemorrhage	FIBRINOGEN, HUMAN	targetBased	3			https://www.whocc.no/atc_ddd_index/?code=B02BB01	0.7		protect
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	FGB_inhibitors	FGB	Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]	hemorrhage	FIBRINOGEN, HUMAN	targetBased	4	Completed	26/10/2021	https://clinicaltrials.gov/study/NCT04376762	1		protect
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	FGB_inhibitors	FGB	Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]	hemorrhage	FIBRINOGEN, HUMAN	targetBased	4	Completed	26/10/2021	https://clinicaltrials.gov/study/NCT04376762	1		protect
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	FGB_inhibitors	FGB	Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]	blood coagulation disease	FIBRINOGEN, HUMAN	targetBased	4	Completed	01/06/2010	https://clinicaltrials.gov/study/NCT00994045	1		protect
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )]	FGB_inhibitors	FGB	Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]	blood coagulation disease	FIBRINOGEN, HUMAN	targetBased	4	Completed	01/06/2010	https://clinicaltrials.gov/study/NCT00994045	1		protect
Counterscreen for Oxytocin Receptor (OXTR) agonists: Fluorescence-based primary cell-based high throughput assay to identify agonists of the vasopressin 1 receptor (V1R)	AVPR1A_agonists	AVPR1A	Vasopressin V1a receptor	hemorrhage	TERLIPRESSIN	targetBased	2	Completed	01/09/2015	https://clinicaltrials.gov/study/NCT02588716	0.2		protect
Counterscreen for Oxytocin Receptor (OXTR) agonists: Fluorescence-based primary cell-based high throughput assay to identify agonists of the vasopressin 1 receptor (V1R)	AVPR1A_agonists	AVPR1A	Vasopressin V1a receptor	hemorrhage	TERLIPRESSIN	targetBased	4	Unknown status	01/12/2006	https://clinicaltrials.gov/study/NCT00863837	1		protect
Counterscreen for Oxytocin Receptor (OXTR) agonists: Fluorescence-based primary cell-based high throughput assay to identify agonists of the vasopressin 1 receptor (V1R)	AVPR1A_agonists	AVPR1A	Vasopressin V1a receptor	hemorrhage	TERLIPRESSIN	targetBased	2	Completed	01/05/2016	https://clinicaltrials.gov/study/NCT03572088	0.2		protect
Counterscreen for Oxytocin Receptor (OXTR) agonists: Fluorescence-based primary cell-based high throughput assay to identify agonists of the vasopressin 1 receptor (V1R)	AVPR1A_agonists	AVPR1A	Vasopressin V1a receptor	hemorrhage	TERLIPRESSIN	targetBased	4	Completed	01/05/2010	https://clinicaltrials.gov/study/NCT02757703	1		protect
Counterscreen for Oxytocin Receptor (OXTR) agonists: Fluorescence-based primary cell-based high throughput assay to identify agonists of the vasopressin 1 receptor (V1R)	AVPR1A_agonists	AVPR1A	Vasopressin V1a receptor	hemorrhage	TERLIPRESSIN	targetBased	3	Not yet recruiting	01/09/2023	https://clinicaltrials.gov/study/NCT06027970	0.7		protect
Counterscreen for Oxytocin Receptor (OXTR) agonists: Fluorescence-based primary cell-based high throughput assay to identify agonists of the vasopressin 1 receptor (V1R)	AVPR1A_agonists	AVPR1A	Vasopressin V1a receptor	hemorrhage	TERLIPRESSIN	targetBased	4	Completed	07/05/2018	https://clinicaltrials.gov/study/NCT03584087	1		protect
Counterscreen for Oxytocin Receptor (OXTR) agonists: Fluorescence-based primary cell-based high throughput assay to identify agonists of the vasopressin 1 receptor (V1R)	AVPR1A_agonists	AVPR1A	Vasopressin V1a receptor	Hemoptysis	TERLIPRESSIN	targetBased	3	Recruiting	27/03/2022	https://clinicaltrials.gov/study/NCT04961528	0.7		protect
HTS of Estrogen Receptor- alpha Coactivator Binding inhibitors	ESR1_inhibitors	ESR1	Estrogen receptor, Estrogen receptor	hemorrhage	CLOMIPHENE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=834802c8-911f-55e7-e053-2a91aa0a5c7d	1		protect
HTS of Estrogen Receptor- alpha Coactivator Binding Potentiators	ESR1_modulators	ESR1	Estrogen receptor, Estrogen receptor	hemorrhage	CLOMIPHENE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=834802c8-911f-55e7-e053-2a91aa0a5c7d	1		protect
qHTS for Inhibitors of TGF-b	TGFB1	TGFB1	HSPC193, Mothers against decapentaplegic homolog 3	anemia	LUSPATERCEPT	pathwayBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=82f4d266-3f52-41eb-86ba-0abf3cf468e8	1	LoF	protect
qHTS for Inhibitors of TGF-b	TGFB1	TGFB1	HSPC193, Mothers against decapentaplegic homolog 3	anemia (phenotype)	LUSPATERCEPT	pathwayBased	4			https://www.ema.europa.eu/en/medicines/human/EPAR/reblozyl	1	LoF	protect
qHTS for Inhibitors of TGF-b	TGFB1	TGFB1	HSPC193, Mothers against decapentaplegic homolog 3	anemia (phenotype)	LUSPATERCEPT	pathwayBased	2	Completed	01/01/2013	https://clinicaltrials.gov/study/NCT01749514	0.2	LoF	protect
qHTS for Inhibitors of TGF-b	TGFB1	TGFB1	HSPC193, Mothers against decapentaplegic homolog 3	anemia (phenotype)	LUSPATERCEPT	pathwayBased	4			https://www.whocc.no/atc_ddd_index/?code=B03XA06	1	LoF	protect
qHTS for Inhibitors of TGF-b	TGFB1	TGFB1	HSPC193, Mothers against decapentaplegic homolog 3	anemia (phenotype)	LUSPATERCEPT	pathwayBased	2	Recruiting	09/12/2022	https://clinicaltrials.gov/study/NCT05664737	0.2	LoF	protect
qHTS for Inhibitors of TGF-b	TGFB1	TGFB1	HSPC193, Mothers against decapentaplegic homolog 3	Thalassemia	LUSPATERCEPT	pathwayBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=82f4d266-3f52-41eb-86ba-0abf3cf468e8	1	LoF	protect
qHTS for Inhibitors of TGF-b	TGFB1	TGFB1	HSPC193, Mothers against decapentaplegic homolog 3	Thalassemia	LUSPATERCEPT	pathwayBased	2	Completed	05/02/2018	https://clinicaltrials.gov/study/NCT03342404	0.2	LoF	protect
qHTS for Inhibitors of TGF-b	TGFB1	TGFB1	HSPC193, Mothers against decapentaplegic homolog 3	Aplastic anemia	LUSPATERCEPT	pathwayBased	2	Not yet recruiting	01/07/2022	https://clinicaltrials.gov/study/NCT05399732	0.2	LoF	protect
HTS of Estrogen Receptor- alpha Coactivator Binding inhibitors	ESR1_inhibitors	ESR1	Estrogen receptor, Estrogen receptor	hemorrhage	CLOMIPHENE CITRATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=834802c8-911f-55e7-e053-2a91aa0a5c7d	1		protect
HTS of Estrogen Receptor- alpha Coactivator Binding Potentiators	ESR1_modulators	ESR1	Estrogen receptor, Estrogen receptor	hemorrhage	CLOMIPHENE CITRATE	targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=834802c8-911f-55e7-e053-2a91aa0a5c7d	1		protect
Fluorescence-based primary cell-based high throughput screening assay to identify agonists of the Oxytocin Receptor (OXTR).	OXTR	OXTR	Oxytocin receptor	hemorrhage	CARBETOCIN	targetBased	4	Completed	01/05/2014	https://clinicaltrials.gov/study/NCT02101567	1	GoF	protect
Fluorescence-based primary cell-based high throughput screening assay to identify agonists of the Oxytocin Receptor (OXTR).	OXTR	OXTR	Oxytocin receptor	hemorrhage	CARBETOCIN	targetBased	4	Completed	01/06/2014	https://clinicaltrials.gov/study/NCT02044549	1	GoF	protect
Fluorescence-based primary cell-based high throughput screening assay to identify agonists of the Oxytocin Receptor (OXTR).	OXTR	OXTR	Oxytocin receptor	hemorrhage	CARBETOCIN	targetBased	4	Not yet recruiting	01/11/2020	https://clinicaltrials.gov/study/NCT04595812	1	GoF	protect
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	hemorrhage		targetBased	3	Terminated	24/09/2013	https://clinicaltrials.gov/study/NCT01913483	0.7	LoF	protect
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	hemorrhage		targetBased	3	Completed	01/01/2008	https://clinicaltrials.gov/study/NCT01465503	0.7	LoF	protect
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	Recurrent thrombophlebitis		targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=911cd48f-01ea-4dec-b30c-95e7e0ea9d2a	1	LoF	protect
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	Recurrent thrombophlebitis		targetBased	4			https://www.whocc.no/atc_ddd_index/?code=B01AE06	1	LoF	protect
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	Recurrent thrombophlebitis		targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=799d3b00-809b-4abc-989c-05faccec49f8	1	LoF	protect
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	Thrombocytopenia		targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=799d3b00-809b-4abc-989c-05faccec49f8	1	LoF	protect
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	Thrombocytopenia		targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=50975be1-6d1f-497c-b989-1825a0fae1a7	1	LoF	protect
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	Thrombocytopenia		targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=911cd48f-01ea-4dec-b30c-95e7e0ea9d2a	1	LoF	protect
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	Thrombocytopenia		targetBased	3	Completed	01/10/2003	https://clinicaltrials.gov/study/NCT00073580	0.7	LoF	protect
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	Thrombocytopenia		targetBased	3	Completed	01/04/1999	https://clinicaltrials.gov/study/NCT00043940	0.7	LoF	protect
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	Thrombocytopenia		targetBased	4			https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5f133813-f74e-4508-bc64-debbf104ff1e	1	LoF	protect
Thrombin 1536 HTS	F2_modulation	F2	Prothrombin	Abnormality of blood and blood-forming tissues		targetBased	3	Completed	01/02/2008	https://clinicaltrials.gov/study/NCT00616460	0.7	LoF	protect

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