| 1272966 | Carbonic anhydrase | 2.042866 | 4 | actual&Predicted | Anopheles gambiae (African malaria mosquito) | arthropoda | Enzyme |
| 1MB.92 | Histone deacetylase | 4.430808 | 16 | actual&Predicted | Cryptosporidium parvum | protozoan | HDAC class I |
| 56k.08 | Histone deacetylase | 4.546984 | 18 | actual&Predicted | Cryptosporidium parvum | protozoan | HDAC class I |
| A6YCJ1 | Astrosclerin-3 | 1.980114 | 4 | actual&Predicted | Astrosclera willeyana | notRecorded | Unclassified protein |
| Abat | 4-aminobutyrate aminotransferase, mitochondrial | 1.868148 | 1 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) - Sus scrofa (Pig) | mammals | Transferase |
| ABCB1 | ATP-dependent translocase ABCB1 - Multidrug resistance protein 1 | 3.132702 | 284 | actual&Predicted | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) - Homo sapiens (Human) - Rattus norvegicus (Rat) | widespread | ABCB subfamily |
| Abcb11 | Bile salt export pump | 3.236667 | 57 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | ABCB subfamily |
| Abcc1 | Multidrug resistance-associated protein 1 | 3.322827 | 227 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | ABCC subfamily |
| Abcc2 | Canalicular multispecific organic anion transporter 1 | 2.843115 | 50 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | ABCC subfamily |
| ABCC4 | Multidrug resistance-associated protein 4 | 2.810116 | 21 | actual&Predicted | Homo sapiens (Human) | mammals | ABCC subfamily |
| Abcg2 | Broad substrate specificity ATP-binding cassette transporter ABCG2 | 2.442336 | 40 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | ABCG subfamily |
| ACAT | Acyl-CoA:cholesterol acyltransferase | 2.907442 | 56 | actual&Predicted | Oryctolagus cuniculus (Rabbit) | mammals | Enzyme |
| ache | Acetylcholinesterase | 2.515178 | 454 | actual&Predicted | Anopheles gambiae (African malaria mosquito) - Bos taurus (Bovine) - Danio rerio (Zebrafish) (Brachydanio rerio) - Drosophila melanogaster (Fruit fly) - Electrophorus electricus (Electric eel) (Gymnotus electricus) - Gallus gallus (Chicken) - Homo sapiens (Human) - Leptinotarsa decemlineata (Colorado potato beetle) (Doryphora decemlineata) - Mus musculus (Mouse) - Rattus norvegicus (Rat) - Tetronarce californica (Pacific electric ray) (Torpedo californica) | widespread | Hydrolase |
| ADCY1 | Adenylate cyclase type 1 | 3.151987 | 11 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) | mammals | Enzyme |
| Adcy2 | Adenylate cyclase type 2 | 3.34193 | 12 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Lyase |
| Adora1 | Adenosine receptor A1 | 2.204065 | 110 | actual&Predicted | Bos taurus (Bovine) - Cavia porcellus (Guinea pig) - Gallus gallus (Chicken) - Homo sapiens (Human) - Mus musculus (Mouse) - Oryctolagus cuniculus (Rabbit) - Rattus norvegicus (Rat) | mammals | Adenosine receptor, Unclassified protein |
| ADORA3 | Adenosine receptor A3 | 2.27828 | 67 | actual&Predicted | Bos taurus (Bovine) - Canis lupus familiaris (Dog) (Canis familiaris) - Homo sapiens (Human) - Mus musculus (Mouse) - Oryctolagus cuniculus (Rabbit) - Ovis aries (Sheep) - Rattus norvegicus (Rat) | mammals | Adenosine receptor |
| ADRA2B | Alpha-2B adrenergic receptor | 2.377486 | 140 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Adrenergic receptor |
| ADRB2 | Beta-2 adrenergic receptor | 2.211181 | 76 | actual&Predicted | Bos taurus (Bovine) - Canis lupus familiaris (Dog) (Canis familiaris) - Cavia porcellus (Guinea pig) - Homo sapiens (Human) - Mesocricetus auratus (Golden hamster) - Mus musculus (Mouse) - Rattus norvegicus (Rat) - Sus scrofa (Pig) | mammals | Adrenergic receptor |
| ADRB3 | Beta-3 adrenergic receptor | 2.269872 | 60 | actual&Predicted | Canis lupus familiaris (Dog) (Canis familiaris) - Homo sapiens (Human) - Macaca mulatta (Rhesus macaque) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Adrenergic receptor |
| AHR | Aryl hydrocarbon receptor | 2.190074 | 12 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Oryctolagus cuniculus (Rabbit) - Rattus norvegicus (Rat) | mammals | Transcription factor |
| AKT1 | RAC-alpha serine/threonine-protein kinase | 2.622901 | 263 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | AGC protein kinase AKT family |
| ALB | Serum albumin | 2.651308 | 53 | actual&Predicted | Bos taurus (Bovine) - Equus caballus (Horse) - Homo sapiens (Human) - Mus musculus (Mouse) - Oryctolagus cuniculus (Rabbit) - Rattus norvegicus (Rat) | mammals | Secreted protein |
| ald | Putative fructose-1,6-bisphosphate aldolase | 2.358602 | 119 | actual&Predicted | Giardia intestinalis (Giardia lamblia) | notApplicabe | Enzyme |
| ALDH1A1 | Retinal dehydrogenase 1 | 2.371464 | 209 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Oxidoreductase |
| ALDH5A1 | Succinate-semialdehyde dehydrogenase, mitochondrial | 3.338075 | 1 | actual&Predicted | Homo sapiens (Human) | mammals | Oxidoreductase |
| Alk | ALK tyrosine kinase receptor | 2.650127 | 124 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | TKL protein kinase STKR Type 1 subfamily, Tyrosine protein kinase Alk family |
| ALOX12 | Arachidonate 12-lipoxygenase, 12S-type | 2.47017 | 57 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Enzyme |
| ALOX15 | Arachidonate 15-lipoxygenase - Probable linoleate 9S-lipoxygenase 5 | 2.217103 | 111 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Oryctolagus cuniculus (Rabbit) - Rattus norvegicus (Rat) - Solanum tuberosum (Potato) - Sus scrofa (Pig) | widespread | Oxidoreductase |
| ALOX15B | Arachidonate 15-lipoxygenase B | 2.376985 | 141 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Oxidoreductase |
| ALOX5 | Arachidonate 5-lipoxygenase | 2.343246 | 101 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Oxidoreductase |
| ALPI | Intestinal-type alkaline phosphatase | 2.08119 | 7 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Phosphatase |
| APEX1 | DNA-(apurinic or apyrimidinic site) lyase | 2.294566 | 174 | actual&Predicted | Homo sapiens (Human) | mammals | Enzyme |
| APOBEC3G | DNA dC->dU-editing enzyme APOBEC-3G | 2.124315 | 57 | actual&Predicted | Homo sapiens (Human) | mammals | Hydrolase |
| APP | Amyloid-beta A4 protein - Amyloid-beta precursor protein | 2.485581 | 104 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Membrane receptor |
| AR | Androgen receptor | 2.336664 | 140 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Nuclear hormone receptor subfamily 3 group C member 4 |
| aroQ | 3-dehydroquinate dehydratase | 1.641851 | 1 | actual&Predicted | Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) - Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) - Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) | bacteria | Lyase |
| ATAD5 | ATPase family AAA domain-containing protein 5 | 2.348577 | 323 | actual&Predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| ATM | Serine-protein kinase ATM | 2.288104 | 12 | actual&Predicted | Homo sapiens (Human) | mammals | Atypical protein kinase PIKK family |
| ATXN2 | Ataxin-2 | 2.123454 | 211 | actual&Predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| AXL | Tyrosine-protein kinase receptor UFO | 2.344726 | 73 | actual&Predicted | Homo sapiens (Human) | mammals | Tyrosine protein kinase Axl family |
| BACE1 | Beta-secretase 1 | 2.557365 | 226 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Aspartic protease A1A subfamily |
| BCHE | Cholinesterase | 2.58102 | 269 | actual&Predicted | Equus caballus (Horse) - Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Hydrolase |
| BCL2 | Apoptosis regulator Bcl-2 | 4.553418 | 1397 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Bcl-2 family |
| bla(tem-2) | Beta-lactamase | 2.354857 | 8 | actual&Predicted | Pseudomonas aeruginosa | bacteria | Hydrolase |
| BLM | Bloom syndrome protein | 2.358842 | 97 | actual&Predicted | Homo sapiens (Human) | mammals | Enzyme |
| BRCA1 | Breast cancer type 1 susceptibility protein | 2.275611 | 43 | actual&Predicted | Homo sapiens (Human) | mammals | Enzyme |
| BRD2 | Bromodomain-containing protein 2 | 2.773361 | 22 | actual&Predicted | Homo sapiens (Human) | mammals | Bromodomain |
| BRD3 | Bromodomain-containing protein 3 | 2.850419 | 24 | actual&Predicted | Homo sapiens (Human) | mammals | Bromodomain |
| BRD4 | Bromodomain-containing protein 4 | 2.729343 | 130 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Bromodomain |
| BRDT | Bromodomain testis-specific protein | 2.703399 | 5 | actual&Predicted | Homo sapiens (Human) | mammals | Bromodomain |
| BS1330_II0781 | Carbonic anhydrase | 1.901844 | 3 | actual&Predicted | Brucella suis biovar 1 (strain 1330) | bacteria | Lyase |
| CA | Alpha carbonic anhydrase | 2.017725 | 4 | actual&Predicted | Stylophora pistillata (Smooth cauliflower coral) | notRecorded | Enzyme |
| ca1 | Delta carbonic anhydrase | 2.040921 | 4 | actual&Predicted | Thalassiosira weissflogii (Marine diatom) | notRecorded | Enzyme |
| CA1 | Carbonic anhydrase 1 | 1.998478 | 59 | actual&Predicted | Equus caballus (Horse) - Homo sapiens (Human) - Macaca mulatta (Rhesus macaque) | mammals | Lyase |
| CA12 | Carbonic anhydrase 12 | 1.941722 | 35 | actual&Predicted | Homo sapiens (Human) | mammals | Lyase |
| CA13 | Carbonic anhydrase 13 | 2.024151 | 10 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Lyase |
| CA14 | Carbonic anhydrase 14 | 2.033324 | 16 | actual&Predicted | Homo sapiens (Human) | mammals | Lyase |
| Ca15 | Carbonic anhydrase 15 | 2.065059 | 7 | actual&Predicted | Mus musculus (Mouse) | mammals | Lyase |
| CA2 | Carbonic anhydrase 2 | 1.996717 | 66 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Lyase |
| CA2 | Carbonic anhydrase | 2.072819 | 4 | actual&Predicted | Stylophora pistillata (Smooth cauliflower coral) | notRecorded | Enzyme, Lyase |
| CA3 | Carbonic anhydrase 3 | 2.031243 | 8 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) | mammals | Lyase |
| CA4 | Carbonic anhydrase 4 | 2.108032 | 37 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) | mammals | Lyase |
| CA5A | Carbonic anhydrase 5A, mitochondrial | 2.098097 | 13 | actual&Predicted | Homo sapiens (Human) | mammals | Lyase |
| CA5B | Carbonic anhydrase 5B, mitochondrial | 2.119679 | 14 | actual&Predicted | Homo sapiens (Human) | mammals | Lyase |
| CA6 | Carbonic anhydrase 6 | 2.029925 | 14 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) | mammals | Lyase |
| CA7 | Carbonic anhydrase 7 | 2.095747 | 24 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Lyase |
| CA9 | Carbonic anhydrase 9 | 1.960813 | 40 | actual&Predicted | Homo sapiens (Human) | mammals | Lyase |
| CACNA1C | Voltage-dependent L-type calcium channel subunit alpha-1C | 3.191334 | 135 | actual&Predicted | Cavia porcellus (Guinea pig) - Homo sapiens (Human) - Mus musculus (Mouse) - Oryctolagus cuniculus (Rabbit) - Rattus norvegicus (Rat) | mammals | Voltage-gated calcium channel |
| CAH | Carbonic anhydrase | 2.086593 | 4 | actual&Predicted | Methanosarcina thermophila | notRecorded | Lyase |
| Camk2a | Calcium/calmodulin-dependent protein kinase type II subunit alpha | 2.276196 | 38 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | CAMK protein kinase CAMK2 family |
| CAN2 | Carbonic anhydrase | 2.09589 | 3 | actual&Predicted | Cryptococcus neoformans var. grubii (Filobasidiella neoformans var. grubii) | fungi | Enzyme, Lyase |
| CBFB | Core-binding factor subunit beta | 2.366161 | 66 | actual&Predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| CCND3 | G1/S-specific cyclin-D3 | 2.69785 | 54 | actual&Predicted | Homo sapiens (Human) | mammals | Other cytosolic protein |
| CCNE1 | G1/S-specific cyclin-E1 | 2.409014 | 76 | actual&Predicted | Homo sapiens (Human) | mammals | Other cytosolic protein |
| CDK2 | Cyclin-dependent kinase 2 | 2.321131 | 159 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | CMGC protein kinase CDC2 subfamily, Transferase |
| CDK6 | Cyclin-dependent kinase 6 | 2.369239 | 55 | actual&Predicted | Homo sapiens (Human) | mammals | CMGC protein kinase group |
| CDR1 | Multidrug resistance protein CDR1 | 2.336279 | 1 | actual&Predicted | Candida albicans (Yeast) | fungi | ABCB subfamily |
| CHEK1 | Serine/threonine-protein kinase Chk1 | 2.127701 | 77 | actual&Predicted | Homo sapiens (Human) | mammals | CAMK protein kinase CHK1 subfamily |
| CHEK2 | Serine/threonine-protein kinase Chk2 | 2.216357 | 55 | actual&Predicted | Homo sapiens (Human) | mammals | CAMK protein kinase RAD53 family |
| CRBN | Protein cereblon | 4.397967 | 16 | actual&Predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| CREBBP | CREB-binding protein | 2.42561 | 24 | actual&Predicted | Homo sapiens (Human) | mammals | Bromodomain, p300/CBP family |
| Cyp1a2 | Cytochrome P450 1A2 | 2.108485 | 194 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Cytochrome P450 1A1, Cytochrome P450 1A2 |
| CYP2B6 | Cytochrome P450 2B6 | 2.531639 | 16 | actual&Predicted | Homo sapiens (Human) | mammals | Cytochrome P450 2B6 |
| CYP2C19 | Cytochrome P450 2C19 | 2.172638 | 199 | actual&Predicted | Homo sapiens (Human) | mammals | Cytochrome P450 2C19 |
| CYP2C9 | Cytochrome P450 2C9 | 2.239767 | 228 | actual&Predicted | Homo sapiens (Human) | mammals | Cytochrome P450 2C9 |
| CYP2D6 | Cytochrome P450 2D6 | 2.197044 | 290 | actual&Predicted | Homo sapiens (Human) | mammals | Cytochrome P450 2D6 |
| CYP2J2 | Cytochrome P450 2J2 | 3.151481 | 16 | actual&Predicted | Homo sapiens (Human) | mammals | Enzyme |
| CYP3A4 | Cytochrome P450 3A4 | 2.11263 | 423 | actual&Predicted | Homo sapiens (Human) | mammals | Cytochrome P450 3A4 |
| DDB1 | DNA damage-binding protein 1 | 4.920914 | 7 | actual&Predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| Dnmt1 | DNA | 2.228844 | 2 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | DNA methyltransferase |
| Dnmt3b | DNA | 1.819942 | 1 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | DNA methyltransferase, PWWP domain |
| Drd1 | D(1) dopamine receptor - D(1A) dopamine receptor | 2.513053 | 256 | actual&Predicted | Bos taurus (Bovine) - Carassius auratus (Goldfish) - Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) - Sus scrofa (Pig) | mammals | Dopamine receptor |
| DRD2 | D(2) dopamine receptor | 2.641715 | 992 | actual&Predicted | Bos taurus (Bovine) - Canis lupus familiaris (Dog) (Canis familiaris) - Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops) - Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Dopamine receptor |
| EGFR | Epidermal growth factor receptor | 2.835479 | 582 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Tyrosine protein kinase EGFR family |
| EHMT2 | Histone-lysine N-methyltransferase EHMT2 | 2.21372 | 321 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Protein methyltransferase |
| ELOB | Elongin-B | 4.270065 | 14 | actual&Predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| ELOC | Elongin-C | 4.270065 | 14 | actual&Predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| EP300 | Histone acetyltransferase p300 | 2.305373 | 12 | actual&Predicted | Homo sapiens (Human) | mammals | Bromodomain, p300/CBP family |
| EPHX2 | Bifunctional epoxide hydrolase 2 [Includes: Cytosolic epoxide hydrolase 2 | 2.150597 | 26 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Enzyme, Serine protease S33 family |
| ERBB2 | Receptor tyrosine-protein kinase erbB-2 | 2.849024 | 317 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Tyrosine protein kinase EGFR family |
| ERBB3 | Receptor tyrosine-protein kinase erbB-3 | 2.910237 | 54 | actual&Predicted | Homo sapiens (Human) | mammals | Tyrosine protein kinase EGFR family |
| ERBB4 | Receptor tyrosine-protein kinase erbB-4 | 2.765008 | 105 | actual&Predicted | Homo sapiens (Human) | mammals | Tyrosine protein kinase EGFR family |
| ERG | Transcriptional regulator ERG | 2.211139 | 20 | actual&Predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| ESR1 | Estrogen receptor | 3.060952 | 350 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Mus musculus (Mouse) - Ovis aries (Sheep) - Rattus norvegicus (Rat) | mammals | Nuclear hormone receptor subfamily 3 group A member 1 |
| Esr2 | Estrogen receptor beta | 3.020173 | 238 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Mus musculus (Mouse) - Ovis aries (Sheep) - Rattus norvegicus (Rat) | mammals | Nuclear hormone receptor subfamily 3 group A member 2, Unclassified protein |
| F3 | Tissue factor | 2.441211 | 23 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Membrane receptor, Surface antigen |
| fabI | Enoyl-[acyl-carrier-protein] reductase [NADH] FabI - Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI | 1.798376 | 2 | actual&Predicted | Bacillus subtilis (strain 168) - Escherichia coli (strain K12) - Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) - Staphylococcus aureus (strain MRSA252) - Staphylococcus aureus (strain NCTC 8325) | bacteria | Oxidoreductase |
| ffp | 4'-phosphopantetheinyl transferase ffp | 2.379891 | 75 | actual&Predicted | Bacillus subtilis | bacteria | Transferase |
| FLT3 | Receptor-type tyrosine-protein kinase FLT3 | 2.392331 | 148 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Tyrosine protein kinase PDGFR family |
| FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | 3.079804 | 335 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) - Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | widespread | Transferase |
| FOS | Proto-oncogene c-Fos | 2.266923 | 3 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Transcription factor, Unclassified protein |
| FTL | Ferritin light chain | 2.153695 | 73 | actual&Predicted | Equus caballus (Horse) | mammals | Unclassified protein |
| GAA | Lysosomal alpha-glucosidase | 2.338624 | 46 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Hydrolase |
| GBA | Lysosomal acid glucosylceramidase | 2.301891 | 102 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Enzyme |
| GLO1 | Lactoylglutathione lyase | 2.10772 | 5 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) - Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | widespread | Lyase |
| Glp1r | Glucagon-like peptide 1 receptor | 2.213005 | 545 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Glucagon-like peptide receptor |
| GMNN | Geminin | 2.299658 | 517 | actual&Predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| Gpbar1 | G-protein coupled bile acid receptor 1 | 2.65868 | 39 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Steroid-like ligand receptor |
| Gsk3b | Glycogen synthase kinase-3 beta | 2.03489 | 109 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | CMGC protein kinase GSK family |
| hda106 | HD2 type histone deacetylase HDA106 | 2.160829 | 3 | actual&Predicted | Zea mays (Maize) | plants | Enzyme |
| Hdac1 | Histone deacetylase 1 | 2.348416 | 184 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | HDAC class I |
| HDAC1 | Histone deacetylase | 2.687827 | 2 | actual&Predicted | Plasmodium falciparum | protozoan | HDAC class I |
| Hdac10 | Polyamine deacetylase HDAC10 | 2.368357 | 94 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | HDAC class IIb |
| Hdac11 | Histone deacetylase 11 | 2.366831 | 91 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | HDAC class IV |
| Hdac2 | Hdac2 protein | 1.825219 | 1 | actual&Predicted | Rattus norvegicus (Rat) | mammals | HDAC class I |
| Hdac2 | Histone deacetylase 2 | 2.364637 | 116 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | HDAC class I |
| HDAC3 | Histone deacetylase 3 | 2.345275 | 112 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | HDAC class I |
| HDAC4 | Histone deacetylase 4 | 2.348844 | 102 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Enzyme, HDAC class IIa |
| Hdac5 | Hdac5 protein | 1.825219 | 1 | actual&Predicted | Rattus norvegicus (Rat) | mammals | HDAC class IIa |
| HDAC5 | Histone deacetylase 5 | 2.368846 | 92 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | HDAC class IIa |
| HDAC6 | Histone deacetylase 6 | 2.35819 | 162 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | HDAC class IIb |
| Hdac7 | Histone deacetylase 7 | 2.351183 | 94 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | HDAC class IIa |
| Hdac8 | Histone deacetylase 8 | 2.365042 | 137 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | HDAC class I, HDAC class IIa |
| Hdac9 | Histone deacetylase 9 | 2.367801 | 93 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | HDAC class IIa |
| hdaH | Histone deacetylase-like amidohydrolase | 2.628686 | 1 | actual&Predicted | Alcaligenes sp. (strain DSM 11172) (Bordetella sp. (strain FB188)) | bacteria | Hydrolase |
| HIF1A | Hypoxia-inducible factor 1-alpha | 2.199057 | 125 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Transcription factor |
| HMGB1 | High mobility group protein B1 | 2.327518 | 1 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Unclassified protein |
| HMGCR | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 2.502603 | 20 | actual&Predicted | Homo sapiens (Human) - Mesocricetus auratus (Golden hamster) - Mus musculus (Mouse) - Rattus norvegicus (Rat) - Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) - Sus scrofa (Pig) | mammals | Oxidoreductase |
| HPGD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 2.344878 | 111 | actual&Predicted | Homo sapiens (Human) | mammals | Enzyme |
| Hsd11b1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 2.099718 | 26 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Oxidoreductase |
| Hsd11b2 | Corticosteroid 11-beta-dehydrogenase isozyme 2 | 2.354772 | 11 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Enzyme, Oxidoreductase |
| Hsd17b3 | Testosterone 17-beta-dehydrogenase 3 | 2.715628 | 12 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Oxidoreductase |
| HSP90AA1 | Heat shock protein HSP 90-alpha | 2.998097 | 330 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Other cytosolic protein |
| HTR1A | 5-hydroxytryptamine receptor 1A | 2.528921 | 745 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Serotonin receptor |
| HTT | Huntingtin | 2.414459 | 110 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Unclassified protein |
| IAPP | Islet amyloid polypeptide | 3.477501 | 1 | actual&Predicted | Homo sapiens (Human) | mammals | Secreted protein |
| ICAM1 | Intercellular adhesion molecule 1 | 2.988026 | 71 | actual&Predicted | Homo sapiens (Human) | mammals | Adhesion |
| IDH1 | Isocitrate dehydrogenase [NADP] cytoplasmic | 2.269525 | 285 | actual&Predicted | Homo sapiens (Human) | mammals | Oxidoreductase |
| IMPA1 | Inositol monophosphatase 1 | 2.322061 | 84 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Hydrolase |
| ITGAL | Integrin alpha-L | 3.020499 | 69 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Adhesion, Membrane receptor |
| ITGB2 | Integrin beta-2 | 3.062896 | 70 | actual&Predicted | Homo sapiens (Human) | mammals | Membrane receptor |
| JAK2 | Tyrosine-protein kinase JAK2 | 2.36432 | 220 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Tyrosine protein kinase JakA family, Tyrosine protein kinase JakB family |
| JUN | Transcription factor AP-1 | 2.558329 | 14 | actual&Predicted | Gallus gallus (Chicken) - Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Transcription factor |
| KAT2A | Histone acetyltransferase KAT2A | 2.342264 | 90 | actual&Predicted | Homo sapiens (Human) | mammals | Bromodomain, GNAT family |
| KCNH2 | Potassium voltage-gated channel subfamily H member 2 | 2.621166 | 505 | actual&Predicted | Canis lupus familiaris (Dog) (Canis familiaris) - Cavia porcellus (Guinea pig) - Homo sapiens (Human) - Oryctolagus cuniculus (Rabbit) | mammals | Voltage-gated potassium channel |
| KCNK2 | Potassium channel subfamily K member 2 | 5.02624 | 5 | actual&Predicted | Bos taurus (Bovine) | mammals | Two-pore domain potassium channel |
| KDM4E | Lysine-specific demethylase 4E | 2.321448 | 106 | actual&Predicted | Homo sapiens (Human) | mammals | Jumonji domain-containing |
| Kdr | Vascular endothelial growth factor receptor 2 | 2.587206 | 446 | actual&Predicted | Danio rerio (Zebrafish) (Brachydanio rerio) - Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Tyrosine protein kinase VEGFR family |
| Kit | Mast/stem cell growth factor receptor Kit | 2.616483 | 143 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Tyrosine protein kinase PDGFR family |
| Kmt2a | Histone-lysine N-methyltransferase 2A | 2.389978 | 290 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Bromodomain, Plant homeodomain, Protein methyltransferase |
| KPNB1 | Importin subunit beta-1 | 2.251485 | 47 | actual&Predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| LMNA | Prelamin-A/C [Cleaved into: Lamin-A/C | 2.299744 | 286 | actual&Predicted | Homo sapiens (Human) | mammals | Other nuclear protein, Structural protein |
| LUCI | Coelenterazine h 2-monooxygenase - Luciferin 4-monooxygenase | 2.263174 | 117 | actual&Predicted | Aquatica lateralis (Heike firefly) (Luciola lateralis) - Photinus pyralis (Common eastern firefly) (Lampyris pyralis) - Photuris pensylvanica (Pennsylania firefly) - Renilla reniformis (Sea pansy) | arthropoda | Enzyme, Oxidoreductase |
| MAPK1 | Mitogen-activated protein kinase 1 | 2.347294 | 291 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | CMGC protein kinase ERK subfamily, CMGC protein kinase ERK1 |
| Mapk14 | Mitogen-activated protein kinase 14 | 2.73706 | 338 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | CMGC protein kinase p38 subfamily |
| MAPT | Microtubule-associated protein tau | 2.167214 | 304 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Other cytosolic protein |
| MEN1 | Menin | 2.394322 | 272 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Unclassified protein |
| MET | Hepatocyte growth factor receptor | 2.522218 | 248 | actual&Predicted | Canis lupus familiaris (Dog) (Canis familiaris) - Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Tyrosine protein kinase Met family |
| MMP13 | Collagenase 3 | 2.269832 | 28 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Hydrolase, Metallo protease M10A subfamily |
| MMP2 | 72 kDa type IV collagenase | 2.260986 | 64 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Metallo protease M10A subfamily |
| MMP9 | Matrix metalloproteinase-9 | 2.258819 | 58 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Metallo protease M10A subfamily |
| MT-CO1 | Cytochrome c oxidase subunit 1 | 2.148665 | 1 | actual&Predicted | Homo sapiens (Human) - Ovis aries (Sheep) | mammals | Oxidoreduction-driven transporters |
| MT-CO2 | Cytochrome c oxidase subunit 2 | 2.682367 | 3 | actual&Predicted | Homo sapiens (Human) - Ovis aries (Sheep) | mammals | Enzyme, Oxidoreduction-driven transporters |
| MT-ND4 | NADH-ubiquinone oxidoreductase chain 4 | 1.952029 | 2 | actual&Predicted | Homo sapiens (Human) | mammals | Oxidoreductase |
| mtcA1 | Beta-carbonic anhydrase 1 | 1.890014 | 4 | actual&Predicted | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | bacteria | Lyase |
| mtcA2 | Carbonic anhydrase 2 | 2.008713 | 3 | actual&Predicted | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | bacteria | Lyase |
| NAMPT | Nicotinamide phosphoribosyltransferase | 2.14852 | 23 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Enzyme |
| nanH | Sialidase | 2.230197 | 4 | actual&Predicted | Clostridium perfringens - Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) | bacteria | Hydrolase |
| NCE103 | Carbonic anhydrase | 2.176695 | 5 | actual&Predicted | Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata) | fungi | Lyase |
| NCE103 | Carbonic anhydrase | 2.002934 | 4 | actual&Predicted | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) - Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | fungi | Lyase |
| NCOR2 | Nuclear receptor corepressor 2 | 2.438198 | 12 | actual&Predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| Nfe2l2 | Nuclear factor erythroid 2-related factor 2 | 2.210433 | 331 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Unclassified protein |
| NFKB1 | Nuclear factor NF-kappa-B p105 subunit | 2.314825 | 68 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Other cytosolic protein, Transcription factor |
| NFKB2 | Nuclear factor NF-kappa-B p100 subunit | 2.33562 | 16 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Other cytosolic protein, Transcription factor |
| norA | Quinolone resistance protein NorA | 2.974028 | 58 | actual&Predicted | Staphylococcus aureus | bacteria | Unclassified protein |
| Nos2 | Nitric oxide synthase, inducible | 2.113841 | 21 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Enzyme |
| Npsr1 | Neuropeptide S receptor | 2.431556 | 108 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Neuropeptide receptor |
| NR0B1 | Nuclear receptor subfamily 0 group B member 1 | 2.345073 | 4 | actual&Predicted | Homo sapiens (Human) | mammals | Nuclear hormone receptor subfamily 0 group B member 1 |
| Nr1h4 | Bile acid receptor | 2.58515 | 50 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Nuclear hormone receptor subfamily 1 group H member 4, Unclassified protein |
| NR1I2 | Nuclear receptor subfamily 1 group I member 2 | 2.528286 | 31 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Nuclear hormone receptor subfamily 1 group I member 2 |
| NR3C1 | Glucocorticoid receptor | 2.841754 | 244 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Nuclear hormone receptor subfamily 3 group C member 1 |
| NRAM | Neuraminidase | 2.26094 | 7 | actual&Predicted | Influenza A virus (strain A/Aichi/2/1968 H3N2) - Influenza A virus (strain A/Brevig Mission/1/1918 H1N1) (Influenza A virus (strain A/South Carolina/1/1918 H1N1)) - Influenza A virus (strain A/Memphis/1/1971 H3N2) - Influenza A virus (strain A/Puerto Rico/8/1934 H1N1) - Influenza A virus (strain A/Udorn/1972 H3N2) - Influenza A virus (strain A/USSR/90/1977 H1N1) - Influenza A virus (strain A/Wilson-Smith/1933 H1N1) (Influenza A virus (strain A/WS/1933 H1N1)) - Influenza B virus (strain B/Lee/1940) | virus | Enzyme, Hydrolase |
| Pde5a | cGMP-specific 3',5'-cyclic phosphodiesterase | 2.225093 | 21 | actual&Predicted | Bos taurus (Bovine) - Canis lupus familiaris (Dog) (Canis familiaris) - Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Phosphodiesterase 5A |
| Pdgfrb | Platelet-derived growth factor receptor beta | 2.531389 | 163 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Tyrosine protein kinase PDGFR family |
| pepN | Aminopeptidase N | 2.04096 | 6 | actual&Predicted | Bos taurus (Bovine) - Escherichia coli (strain K12) - Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) - Sus scrofa (Pig) | widespread | Metallo protease M1 family |
| pfk | ATP-dependent 6-phosphofructokinase | 2.331775 | 82 | actual&Predicted | Trypanosoma brucei brucei - Trypanosoma cruzi (strain CL Brener) | protozoan | Enzyme |
| PGR | Progesterone receptor | 2.830062 | 5 | actual&Predicted | Bos taurus (Bovine) | mammals | Nuclear hormone receptor subfamily 3 group C member 3 |
| PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | 2.840114 | 541 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Transferase |
| PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | 2.705941 | 182 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Transferase |
| PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | 2.761182 | 241 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Transferase |
| PIK3CG | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.626965 | 155 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Transferase |
| Pik3r1 | Phosphatidylinositol 3-kinase regulatory subunit alpha | 2.93551 | 196 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Enzyme |
| PIN1 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | 2.23377 | 90 | actual&Predicted | Homo sapiens (Human) | mammals | Isomerase |
| PLIN1 | Perilipin-1 | 2.254732 | 8 | actual&Predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| PLK1 | Serine/threonine-protein kinase PLK1 | 2.361027 | 205 | actual&Predicted | Homo sapiens (Human) - Xenopus laevis (African clawed frog) | mammals | Other protein kinase PLK family |
| Pmp22 | Peripheral myelin protein 22 | 2.610618 | 136 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Unclassified protein |
| POLB | DNA polymerase beta | 2.260187 | 49 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Enzyme |
| Poli | DNA polymerase iota | 2.226193 | 133 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Transferase |
| POLK | DNA polymerase kappa | 2.190928 | 95 | actual&Predicted | Homo sapiens (Human) | mammals | Enzyme |
| Ppard | Peroxisome proliferator-activated receptor delta | 2.286322 | 34 | actual&Predicted | Canis lupus familiaris (Dog) (Canis familiaris) - Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Nuclear hormone receptor subfamily 1 group C member 2 |
| Pparg | Peroxisome proliferator-activated receptor gamma | 2.381361 | 72 | actual&Predicted | Canis lupus familiaris (Dog) (Canis familiaris) - Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Nuclear hormone receptor subfamily 1 group C member 3 |
| PPARGC1A | Peroxisome proliferator-activated receptor gamma coactivator 1-alpha | 3.814768 | 2 | actual&Predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| PPO2 | Polyphenol oxidase 2 | 2.041032 | 25 | actual&Predicted | Agaricus bisporus (White button mushroom) | fungi | Oxidoreductase |
| PRKCA | Protein kinase C alpha type | 2.724637 | 127 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | AGC protein kinase PKC alpha subfamily |
| Prkcd | Protein kinase C delta type | 2.749074 | 123 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | AGC protein kinase PKC delta subfamily |
| Prkce | Protein kinase C epsilon type | 2.784238 | 101 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | AGC protein kinase PKC eta subfamily |
| Prkcq | Protein kinase C theta type | 2.764168 | 133 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | AGC protein kinase PKC delta subfamily, AGC protein kinase PKC family, AGC protein kinase PKC theta |
| Prss2 | Anionic trypsin - Anionic trypsin-2 - Trypsin-2 | 2.449594 | 39 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Serine protease S1A subfamily |
| PRSS3 | Trypsin-3 | 2.476699 | 42 | actual&Predicted | Homo sapiens (Human) | mammals | Serine protease S1A subfamily |
| PTGES | Prostaglandin E synthase | 2.66251 | 82 | actual&Predicted | Bos taurus (Bovine) - Canis lupus familiaris (Dog) (Canis familiaris) - Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Isomerase |
| PTGS1 | Prostaglandin G/H synthase 1 | 2.362554 | 44 | actual&Predicted | Bos taurus (Bovine) - Canis lupus familiaris (Dog) (Canis familiaris) - Homo sapiens (Human) - Mus musculus (Mouse) - Oryctolagus cuniculus (Rabbit) - Ovis aries (Sheep) - Rattus norvegicus (Rat) | mammals | Oxidoreductase |
| PTGS2 | Cyclooxygenase 2 | 2.13589 | 1 | actual&Predicted | Canis lupus familiaris (Dog) (Canis familiaris) | mammals | Enzyme |
| PTGS2 | Prostaglandin G/H synthase 2 | 2.317366 | 61 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Mus musculus (Mouse) - Oryctolagus cuniculus (Rabbit) - Ovis aries (Sheep) - Rattus norvegicus (Rat) | mammals | Oxidoreductase |
| PTPN1 | Tyrosine-protein phosphatase non-receptor type 1 | 2.461789 | 152 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Tyrosine protein phosphatase |
| Q39829 | Lipoxygenase | 2.476985 | 2 | actual&Predicted | Glycine max (Soybean) (Glycine hispida) | plants | Enzyme |
| Q99P97 | Histone deacetylase 6 | 1.824955 | 1 | actual&Predicted | Rattus norvegicus (Rat) | mammals | HDAC class IIb |
| RAM1 | Protein farnesyltransferase subunit beta | 3.075043 | 334 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) - Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | widespread | Transferase |
| RAPGEF4 | Rap guanine nucleotide exchange factor 4 | 2.198795 | 48 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Unclassified protein |
| RARA | Retinoic acid receptor alpha | 2.532171 | 32 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Nuclear hormone receptor subfamily 1 group B member 1 |
| RARB | Retinoic acid receptor beta | 2.37578 | 30 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Nuclear hormone receptor subfamily 1 group B member 2 |
| RARG | Retinoic acid receptor gamma | 2.457694 | 24 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Nuclear hormone receptor subfamily 1 group B member 3 |
| RELA | Transcription factor p65 | 2.314388 | 19 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Transcription factor |
| rep | Replicase polyprotein 1ab | 5.239832 | 147 | actual | Human SARS coronavirus (SARS-CoV) (Severe acute respiratory syndrome coronavirus) | virus | Enzyme |
| RET | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.322084 | 90 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Tyrosine protein kinase Ret family |
| RGS4 | Regulator of G-protein signaling 4 | 2.279574 | 77 | actual&Predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| RORC | Nuclear receptor ROR-gamma | 2.430667 | 486 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Nuclear hormone receptor subfamily 1 group F member 3 |
| RUNX1 | Runt-related transcription factor 1 | 2.370204 | 66 | actual&Predicted | Homo sapiens (Human) | mammals | Transcription factor |
| Rv3273 | Probable transmembrane carbonic anhydrase | 1.905268 | 3 | actual&Predicted | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | bacteria | Enzyme |
| Rxfp1 | Relaxin receptor 1 | 2.098675 | 8 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Relaxin receptor |
| RXFP2 | Relaxin receptor 2 | 2.400943 | 5 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Relaxin receptor |
| RXRA | Retinoic acid receptor RXR-alpha | 2.483413 | 67 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Nuclear hormone receptor subfamily 2 group B member 1 |
| RXRB | Retinoic acid receptor RXR-beta | 2.138673 | 6 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Nuclear hormone receptor subfamily 2 group B member 2 |
| Rxrg | Retinoic acid receptor RXR-gamma | 2.103265 | 6 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Nuclear hormone receptor subfamily 2 group B member 3 |
| Scn1a | Sodium channel protein type 1 subunit alpha | 2.779881 | 37 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Voltage-gated sodium channel |
| Scn2a | Sodium channel protein type 2 subunit alpha | 2.83494 | 78 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Voltage-gated sodium channel |
| Scn3a | Sodium channel protein type 3 subunit alpha | 2.787236 | 42 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Voltage-gated sodium channel |
| SIRT1 | NAD-dependent protein deacetylase sirtuin-1 | 2.361083 | 22 | actual&Predicted | Homo sapiens (Human) | mammals | HDAC class III |
| ska | Streptokinase A | 2.448515 | 50 | actual&Predicted | Streptococcus pyogenes serotype M1 | bacteria | Kinase |
| Slc22a19 | Solute carrier family 22 member 19 | 3.484609 | 1 | actual&Predicted | Mus musculus (Mouse) | mammals | Unclassified protein |
| Slc22a5 | Solute carrier family 22 member 5 | 2.012476 | 2 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | SLC22 family of organic cation and anion transporters |
| Slc22a6 | Solute carrier family 22 member 6 | 2.749917 | 9 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | SLC22 family of organic cation and anion transporters |
| SLC2A1 | Solute carrier family 2, facilitated glucose transporter member 1 | 2.262285 | 51 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | SLC02 family of hexose and sugar alcohol transporters |
| Slc6a2 | Sodium-dependent noradrenaline transporter | 2.893414 | 319 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | SLC06 neurotransmitter transporter family |
| Slc6a3 | Sodium-dependent dopamine transporter | 3.088051 | 754 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | SLC06 neurotransmitter transporter family |
| SLC6A4 | Sodium-dependent serotonin transporter | 3.162982 | 1182 | actual&Predicted | Homo sapiens (Human) - Macaca mulatta (Rhesus macaque) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | SLC06 neurotransmitter transporter family |
| SLCO1A2 | Solute carrier organic anion transporter family member 1A2 | 2.891157 | 9 | actual&Predicted | Homo sapiens (Human) | mammals | SLC21/SLCO family of organic anion transporting polypeptides |
| SLCO1B1 | Solute carrier organic anion transporter family member 1B1 | 2.63446 | 212 | actual&Predicted | Homo sapiens (Human) | mammals | SLC21/SLCO family of organic anion transporting polypeptides |
| SLCO1B3 | Solute carrier organic anion transporter family member 1B3 | 2.592582 | 198 | actual&Predicted | Homo sapiens (Human) | mammals | SLC21/SLCO family of organic anion transporting polypeptides |
| SLCO2B1 | Solute carrier organic anion transporter family member 2B1 | 2.957937 | 24 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | SLC21/SLCO family of organic anion transporting polypeptides |
| SMAD2 | Mothers against decapentaplegic homolog 2 | 3.098359 | 2 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Unclassified protein |
| SMAD3 | Mothers against decapentaplegic homolog 3 | 2.070766 | 237 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Unclassified protein |
| SMN1 | Survival motor neuron protein | 2.345972 | 219 | actual&Predicted | Homo sapiens (Human) | mammals | Tudor domain |
| SNCA | Alpha-synuclein | 2.192041 | 86 | actual&Predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| SNUPN | Snurportin-1 | 2.25145 | 47 | actual&Predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| SRC | Neuronal proto-oncogene tyrosine-protein kinase Src - Proto-oncogene tyrosine-protein kinase Src | 2.624883 | 329 | actual&Predicted | Gallus gallus (Chicken) - Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Tyrosine protein kinase Src family |
| sssIM | CPG DNA methylase | 2.032803 | 1 | actual&Predicted | Spiroplasma monobiae (strain ATCC 33825 / MQ-1) | bacteria | Enzyme |
| STAT3 | Signal transducer and activator of transcription 3 | 2.464249 | 22 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Transcription factor |
| SYO3AOP1_0578 | Carbonate dehydratase | 1.970541 | 4 | actual&Predicted | Sulfurihydrogenibium sp. (strain YO3AOP1) | bacteria | Enzyme |
| TACR2 | Substance-K receptor | 3.076857 | 208 | actual&Predicted | Bos taurus (Bovine) - Cavia porcellus (Guinea pig) - Homo sapiens (Human) - Mesocricetus auratus (Golden hamster) - Mus musculus (Mouse) - Oryctolagus cuniculus (Rabbit) - Rattus norvegicus (Rat) | mammals | Neurokinin receptor, Unclassified protein |
| TARDBP | TAR DNA-binding protein 43 | 2.15341 | 136 | actual&Predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| Tcr_1545 | Carbonic anhydrase, alpha family | 1.951527 | 4 | actual&Predicted | Hydrogenovibrio crunogenus (strain XCL-2) (Thiomicrospira crunogena) | bacteria | Lyase |
| TDP1 | Tyrosyl-DNA phosphodiesterase 1 | 2.0542 | 803 | actual&Predicted | Homo sapiens (Human) | mammals | Phosphodiesterase |
| TERT | Telomerase reverse transcriptase | 2.362076 | 38 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Transferase |
| TGR | Thioredoxin glutathione reductase | 2.303613 | 67 | actual&Predicted | Schistosoma mansoni (Blood fluke) | worms | Enzyme |
| THRB | Thyroid hormone receptor beta | 1.938632 | 69 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Nuclear hormone receptor subfamily 1 group A member 2 |
| TLR4 | Toll-like receptor 4 | 3.045283 | 23 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Toll-like and Il-1 receptors |
| Tlr9 | Toll-like receptor 9 | 2.470252 | 11 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Toll-like and Il-1 receptors |
| TOP1 | DNA topoisomerase 1 | 2.656888 | 69 | actual&Predicted | Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops) - Escherichia coli (strain K12) - Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) - Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | widespread | Isomerase |
| TOP2A | DNA topoisomerase 2-alpha | 2.324672 | 63 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) | mammals | Isomerase |
| Tp53 | Cellular tumor antigen p53 | 1.983193 | 243 | actual&Predicted | Homo sapiens (Human) - Mus musculus (Mouse) | mammals | Transcription factor |
| TRY1 | Anionic trypsin-1 - Cationic trypsin - Trypsin-1 | 2.465278 | 100 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Hydrolase, Serine protease S1A subfamily |
| TSHR | Thyrotropin receptor | 2.179486 | 114 | actual&Predicted | Homo sapiens (Human) | mammals | Glycohormone receptor |
| TUBA1A | Tubulin alpha-1A chain | 2.873113 | 75 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) - Sus scrofa (Pig) | mammals | Structural protein |
| TUBA1B | Tubulin alpha-1B chain | 2.880089 | 60 | actual&Predicted | Homo sapiens (Human) | mammals | Structural protein |
| TUBA1C | Tubulin alpha-1C chain | 2.880089 | 60 | actual&Predicted | Homo sapiens (Human) | mammals | Structural protein |
| TUBA3C | Tubulin alpha-3C chain | 2.880084 | 60 | actual&Predicted | Homo sapiens (Human) | mammals | Structural protein |
| TUBA3E | Tubulin alpha-3E chain | 2.880084 | 60 | actual&Predicted | Homo sapiens (Human) | mammals | Structural protein |
| TUBA4A | Tubulin alpha-4A chain | 2.880119 | 60 | actual&Predicted | Homo sapiens (Human) | mammals | Structural protein |
| TUBB | Tubulin beta chain | 2.879798 | 60 | actual&Predicted | Homo sapiens (Human) | mammals | Structural protein |
| TUBB1 | Tubulin beta-1 chain | 2.880198 | 71 | actual&Predicted | Homo sapiens (Human) | mammals | Structural protein |
| TUBB2A | Tubulin beta-2A chain | 2.880089 | 60 | actual&Predicted | Homo sapiens (Human) | mammals | Structural protein |
| TUBB2B | Tubulin beta-2B chain | 2.851914 | 82 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) | mammals | Structural protein |
| TUBB3 | Tubulin beta-3 chain | 2.879997 | 60 | actual&Predicted | Homo sapiens (Human) | mammals | Structural protein |
| TUBB4A | Tubulin beta-4A chain | 2.880054 | 60 | actual&Predicted | Homo sapiens (Human) | mammals | Structural protein |
| TUBB4B | Tubulin beta-4B chain | 2.880621 | 64 | actual&Predicted | Homo sapiens (Human) | mammals | Structural protein |
| TUBB6 | Tubulin beta-6 chain | 2.879998 | 60 | actual&Predicted | Arabidopsis thaliana (Mouse-ear cress) - Homo sapiens (Human) | widespread | Structural protein |
| TUBB8 | Tubulin beta-8 chain | 2.880049 | 60 | actual&Predicted | Homo sapiens (Human) | mammals | Structural protein |
| Txnrd1 | Thioredoxin reductase 1, cytoplasmic | 2.267945 | 155 | actual&Predicted | Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Oxidoreductase |
| UGT1A9 | UDP-glucuronosyltransferase 1-9 | 2.961072 | 4 | actual&Predicted | Homo sapiens (Human) | mammals | Transferase |
| UGT2B15 | UDP-glucuronosyltransferase 2B15 | 3.008983 | 1 | actual&Predicted | Homo sapiens (Human) | mammals | Transferase |
| USP1 | Ubiquitin carboxyl-terminal hydrolase 1 | 1.928067 | 93 | actual&Predicted | Homo sapiens (Human) | mammals | Cysteine protease C19 family |
| USP2 | Ubiquitin carboxyl-terminal hydrolase 2 | 2.165701 | 113 | actual&Predicted | Homo sapiens (Human) | mammals | Cysteine protease C19 family |
| VDR | Vitamin D3 receptor | 2.480289 | 115 | actual&Predicted | Bos taurus (Bovine) - Gallus gallus (Chicken) - Homo sapiens (Human) - Mus musculus (Mouse) - Rattus norvegicus (Rat) - Sus scrofa (Pig) | mammals | Nuclear hormone receptor subfamily 1 group I member 1 |
| VHL | von Hippel-Lindau disease tumor suppressor | 4.412667 | 42 | actual&Predicted | Homo sapiens (Human) | mammals | Unclassified protein |
| Xdh | Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase | 1.876407 | 15 | actual&Predicted | Bos taurus (Bovine) - Homo sapiens (Human) - Rattus norvegicus (Rat) | mammals | Oxidoreductase |
